Preprint Review Version 1 NOT YET PEER-REVIEWED

Synergy Effects in the Chemical Synthesis and Extensions of Multicomponent Reactions (MCRs)The Low Energy Way to Ultra-Short Syntheses of Tailor-Made Molecules

Version 1 : Received: 26 January 2017 / Approved: 26 January 2017 / Online: 26 January 2017 (10:04:55 CET)

A peer-reviewed article of this Preprint also exists.

Eckert, H. Synergy Effects in the Chemical Synthesis and Extensions of Multicomponent Reactions (MCRs)—The Low Energy Way to Ultra-Short Syntheses of Tailor-Made Molecules. Molecules 2017, 22, 349. Eckert, H. Synergy Effects in the Chemical Synthesis and Extensions of Multicomponent Reactions (MCRs)—The Low Energy Way to Ultra-Short Syntheses of Tailor-Made Molecules. Molecules 2017, 22, 349.

Journal reference: Molecules 2017, 22, 349
DOI: 10.3390/molecules22030349

Abstract

Synergistic effects between reactions, reagents and catalysts can lead to minor heats of reaction and occur as an inherent result of multi-component reactions (MCRs) and their extensions. They enable syntheses to be performed at a low energy level and the number of synthesis steps to be drastically reduced in comparison with ‘classical’ two-component reactions. The very high potential for variability, diversity and complexity of MCRs additionally generates an extremely diverse range of products, thus bringing us closer to the aim of being able to produce tailor-made and extremely low-priced materials, drugs and libraries.

Subject Areas

multicomponent reaction; MCR; post condensation modification PCM; post condensation cyclisation PCC; MFCR; multifunction catalysis; variability; diversity; complexity; efficiency of synthesis

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