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Preprint ARTICLE | doi:10.20944/preprints202403.0740.v1

Automated Non-Sterile Pharmacy Compounding: A Multi-Site Study in European Hospital and Community Pharmacies with Pediatric Immediate Release Propranolol Hydrochloride Tablets

Niklas Sandler, Farnaz Shokraneh, Mahsa Bahman, Julius Lahtinen, Niko Hassinen, Sari Airaksinen, Soumya Verma, Ludmila Hrizanovska, Jana Lass, Jyrki Heinämäki, Urve Paaver, Anssi Karlstedt, Janika Tähnas, Christoph Klaas, Catharina Kern, Adeline Bienfait, Frédéric Lagarce, Dominic Fenske, Katrin Muehlenfeld, Julia Malik, Holger Scherliess, Samuli Ojala, Sara P Cruz, Mattias Paulsson, Katja Kammonen, Maria Rautamo, Hendrik Lueck, Herwig Heindl, Laurent Carrez, Antoine Pierrot, Ralf Harnish, Stephanie Stareprawo, Marija Tubic-Grozdanii, Stefanie Zibolka, Uli Loesch, Martina Jeske, Ulrich Griesser, Karin Hummer, Andreas Thalmeier, Marianne Leitner, Susan Bischoff, Ralph Heimke-Brinck, Janine Paulus-Rohmer, Karim Khouckh, Fabien Bruno, Anna Harjans, Torsten Hoppe-Tichy

Subject: Medicine And Pharmacology, Pharmacy Keywords: automated compounding; hospital and community pharmcies; pharm inks; integrated quality control

Online: 13 March 2024 (12:02:20 CET)

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Preprint ARTICLE | doi:10.20944/preprints202311.0630.v1

Optimal Planning of Urban Building-type Integrated Energy Systems Considering Indoor Somatosensory Comfort and PV Consumption

Guangzeng You, Peng Sun, Yi Lei, Donghuizhang Zhang, Haibo Li

Subject: Engineering, Energy And Fuel Technology Keywords: Integrated energy systems (IES); Buildings, Optimization; Indoor somatosensory comfort; PV consumption

Online: 9 November 2023 (11:04:47 CET)

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Preprint ARTICLE | doi:10.20944/preprints202309.1315.v1

Polymer-Embedding Germanium Nanostrip Waveguide of High Polarization Extinction

Jinyuan Liu, Ziyang Zhang

Subject: Physical Sciences, Optics And Photonics Keywords: polymer waveguide technology; integrated optics; germanium waveguide; spectroscopic ellipsometry; hybrid integration

Online: 20 September 2023 (07:43:13 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202304.0572.v1

The Michigan Clinical Consultation and Care model (MC3 Perinatal): A Novel Approach to Perinatal Mental Health Care

Maria Muzik, Rena A. Menke, Meriam Issa, Chelsea Fisk, Jordan Charles, Jennifer M. Jester

Subject: Medicine And Pharmacology, Psychiatry And Mental Health Keywords: perinatal mental health, integrated care, psychiatry consultation, collaborative care, implementation science

Online: 19 April 2023 (08:35:06 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202303.0177.v1

High Precision Information Data Acquisition Method for Mobile Equipment Based on Fractional Partial Differential Equations

Yanhong Zuo, Hua Cheng

Subject: Computer Science And Mathematics, Applied Mathematics Keywords: Integrated Manufacturing; Mobile Equipment; Production Information; Data Accuracy; Fractional Partial Differential

Online: 9 March 2023 (11:38:36 CET)

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Preprint ARTICLE | doi:10.20944/preprints202302.0257.v1

The Design of Piecewise Integrated Composite Bumper Beam With Machine Learning Algorithm

Seokwoo Ham, Seong S. Cheon

Subject: Engineering, Automotive Engineering Keywords: Composite material; Bumper beam; Machine learning; Stacking sequence; Piecewise integrated composite

Online: 15 February 2023 (10:08:12 CET)

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Preprint ARTICLE | doi:10.20944/preprints202301.0038.v1

Health Psychology Services for People in Disadvantaged Regions of Hungary: Experiences from the Primary Care Development Model Program

Viola Sallay, Tamás Martos, Lilla Lucza, Orsolya Papp-Zipernovszky, Márta Csabai

Subject: Social Sciences, Psychology Keywords: community health psychology; primary care; disadvantaged populations; well-being; integrated care

Online: 4 January 2023 (02:13:58 CET)

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Preprint REVIEW | doi:10.20944/preprints202204.0226.v2

Paleomagnetic-Radiometric Mapping of the Transition Zone from Ocean to the Continent: A Review

Lev V. Eppelbaum, Youri I. Katz

Subject: Environmental And Earth Sciences, Geophysics And Geology Keywords: paleomagnetic mapping; paleomagnetic profiling; radiometric dating; tectonic-structural interpretation; integrated study

Online: 5 May 2022 (05:00:57 CEST)

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Preprint REVIEW | doi:10.20944/preprints202012.0260.v1

The Role of Community Radio for Integrated and Sustainable Development in Ethiopia: A Critical Review on the Holistic Approach

Destaw Bayable

Subject: Social Sciences, Anthropology Keywords: Community Radio; Holistic Development; Integrated Development; Sustainable Development; Community Radio Practices

Online: 10 December 2020 (12:59:05 CET)

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Working Paper REVIEW

Review of Photonic Microwave and Radio Frequency Channelizers based on Optical Kerr Micro-combs

mengxi tan, xingyuan xu, David Moss

Subject: Physical Sciences, Optics And Photonics Keywords: Kerr micro-combs; microwave photonics; signal channelization; integrated optical frequency combs

Online: 12 November 2020 (08:53:59 CET)

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Preprint REVIEW | doi:10.20944/preprints202007.0190.v1

Emerging Role of the Integrated Stress Response upon Viral Infection

Yongshu Wu, Xiaodong Qin, Meera Prajapati, Yijing Li, Zhidong Zhang, Yanmin Li

Subject: Biology And Life Sciences, Animal Science, Veterinary Science And Zoology Keywords: integrated stress response; eIF2α phosphorylation; unfolded protein response; viral replication; host

Online: 9 July 2020 (12:22:42 CEST)

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Preprint ARTICLE | doi:10.20944/preprints201907.0253.v1

High-Precision Measurement of a Propagation Loss of Single-Mode Optical Waveguides on Lithium Niobate On Insulator

Jintian Lin, Junxia Zhou, Rongbo Wu, Min Wang, Zhiwei Fang, Wei Chu, Jianhao Zhang, Lingling Qiao, Ya Cheng

Subject: Physical Sciences, Optics And Photonics Keywords: lithium niobate; waveguide; photonic integrated circuit; optical lithography; chemo-mechanical polish

Online: 23 July 2019 (10:03:57 CEST)

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Working Paper ARTICLE

Fabrication of a Multifunctional Photonic Integrated Chip on Lithium Niobate on Insulator Using Femtosecond LaserAssisted Chemo-Mechanical Polish

Rongbo Wu, Jintian Lin, Min Wang, Zhiwei Fang, Wei Chu, Jianhao Zhang, Junxia Zhou, Ya Cheng

Subject: Physical Sciences, Optics And Photonics Keywords: lithium niobate; waveguide; photonic integrated circuit; optical lithography; chemo-mechanical polish

Online: 8 July 2019 (04:09:54 CEST)

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Preprint ARTICLE | doi:10.20944/preprints201906.0191.v1

Utility Value of Water Data for Strategic Planning of Metropolitan Water Supplies

Kyle Wang, Steven Kenway, Matthew Hardy, Christian Urich

Subject: Computer Science And Mathematics, Information Systems Keywords: water data management; urban water system; strategic planning; integrated water management

Online: 20 June 2019 (04:02:14 CEST)

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Preprint CONCEPT PAPER | doi:10.20944/preprints201904.0034.v2

Enhancing Food Safety through Adoption of Long-Term Technical Advisory, Financial and Storage Support Services in Maize Growing Areas of East Africa

Samuel Mutiga, Arnold Mushongi, Erastus Kang'ethe

Subject: Biology And Life Sciences, Agricultural Science And Agronomy Keywords: Maize, Food Safety, Community-based Support systems, Integrated Mycotoxin Control Strategies

Online: 8 April 2019 (13:21:53 CEST)

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Grain production and storage are major components in food security. In the ancient times, food security was achieved through gathering of fruits, grains, herbs, tubers, and roots from the forests by individual households. Advancements in human civilization led to domestication of crops and a need to save food for not only a household, but the nation. This extended need for food security led to establishment of national reservoirs for major produces and this practice varies greatly in different states. Each of the applied food production, handling and storage approaches has got its benefits and challenges. In sub-Saharan Africa, several countries have a public funded budget to subsidize production costs, to buy grains from farmers and to store the produce for a specific period and/or until the next harvests. During the times of famine, the stored grains are later given free to the citizens. If there is no famine, the grain is sold to retailers and/or processors (e.g., millers) who later sell it to the consumers. This approach works well if the produce (mainly grain) is stored under conditions that do not favor growth of molds, as some of these could contaminate the grain with toxic and carcinogenic metabolites called mycotoxins. Conditions that alleviate contamination of grains are required during production, handling and storage. Most of the grain is produced by smallholder farmers under sub-optimal conditions, which make vulnerable to colonization and contamination by toxigenic fungi. Further, the grain is stored in silos at large masses, where it is hard to monitor the conditions at different points of these facilities, and hence it becomes vulnerable to additional contamination. Production and storage of grain under conditions that favor mycotoxins poses major food health and safety risks to humans and livestock who consume the grain. This concept paper focuses on how establishment of local grain production and banking system (LGPBS) could enhance food security and safety in East Africa. The concept of LGPBS provides an extension of advisory and finance support within warehouse receipting system to enhance grain production under optimal conditions. The major practices at the LGPBS, and how each could contribute to food security and safety are discussed. While the concept paper gives more strength on maize production and safety, similar practices could be applied to enhance safety of other grains in the same LGPBS.

Preprint ARTICLE | doi:10.20944/preprints201811.0348.v1

Poisson-Gamma Mixture Spatially Varying Coefficient Modeling of Small-Area Intestinal Parasites Infection

Frank Badu Osei, Alfred Stein, Anthony Ofosu

Subject: Biology And Life Sciences, Parasitology Keywords: intestinal parasites; spatio-temporal; Poisson-gamma; Bayesian; Integrated Nested Laplace Approximations

Online: 15 November 2018 (06:10:13 CET)

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Preprint ARTICLE | doi:10.20944/preprints201809.0381.v1

Integrated Energy Micro-Grid Planning Using Electricity, Heating and Cooling Demands

He HUANG, DaPeng Liang, Zhen Tong

Subject: Engineering, Electrical And Electronic Engineering Keywords: energy internet; multi-energy complementary; integrated energy systems; distribution network planning

Online: 19 September 2018 (10:22:42 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202307.0412.v1

Facile Preparation of SrZr_1-xTi_xO₃ and SrTi_1-xZr_xO₃ Fine Particles Assisted by Dehydration of Zr⁴⁺ and Ti⁴⁺ Gels under Hydrothermal Conditions

J. R. Quiñones-Gurrola, J. C. Rendón-Angeles, Z. Matamoros-Veloza, J. López-Cuevas, R. Pérez-Garibay, K. Yanagisawa

Subject: Chemistry And Materials Science, Chemical Engineering Keywords: hydrothermal synthesis; gel dehydration; SrZrO3–SrTiO3; solid solution; crystallisation; cubic structure; orthorhombic structure

Online: 6 July 2023 (09:11:05 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202305.0681.v1

Atomic Arrangement, Hydrogen Bonding and Structural Com-Plexity of Alunogen, Al2(SO4)3·17H2O, From Kamchatka Geo-Thermal Field

Elena S Zhitova, Rezeda M Sheveleva, Andrey A Zolotarev, Anton A Nuzhdaev

Subject: Environmental And Earth Sciences, Other Keywords: alunogen; sulfate; geothermal field; Kamchatka; hydrated; crystal structure; hydrogen bonding; structure complexity; volcano

Online: 10 May 2023 (04:08:11 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202102.0467.v1

Vegetation Structure Index (VSI): Retrieving Vegetation Structural Information from Multi-angular Satellite Remote Sensing

Ram C. Sharma

Subject: Environmental And Earth Sciences, Atmospheric Science And Meteorology Keywords: Forests; Structure; Biomass; BRDF; MODIS; Multi-angular; NDVI (Fore-Back); Vegetation structure index

Online: 22 February 2021 (12:40:14 CET)

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Utilization of Bidirectional Reflectance Distribution Function (BRDF) model parameters obtained from the multi-angular remote sensing is one of the approaches for the retrieval of vegetation structural information. In this research, the potential of multi-angular vegetation indices, formulated by the combination of multi-spectral reflectance from different view angles, for the retrieval of forest above ground biomass was assessed. This research was implemented in the New England region with the availability of a high quality forest inventory database. The multi-angular vegetation indices were generated by the simulation of the Moderate Resolution Imaging Spectroradiometer (MODIS) BRDF/Albedo Model Parameters Product (MCD43A1 Version 6) based BRDF parameters. The effects of seasonal (spring, summer, autumn, and winter) composites of the multi-angular vegetation indices on above ground biomass, angular relationship of the spectral reflectance with above ground biomass, and the interrelationships between the multi-angular vegetation indices were analyzed. Among the existing multi-angular vegetation indices, only the Nadir BRDF-adjusted NDVI ( and Hot-spot incorporated NDVI ( showed significant relationship (more than 50%) with the above ground biomass. This research proposed two more sensitive vegetation structural indices, Fore-scattering Back-scattering NDVI and Vegetation Structure Index (VSI). The Fore-scattering Back-scattering NDVI showed higher sensitivity (R²= 0.62, RMSE = 52.46) towards the above ground biomass than existing multi-angular vegetation indices. Furthermore, the VSI performed in the most efficient way explaining 64% variation of the above ground biomass, suggesting that the right choice of the spectral channel and observation geometry should be considered for improving the estimates of the above ground biomass. In addition, the right choice of seasonal data (summer) was found to be important for estimating the forest biomass while other seasonal data were either insensitive or pointless. The promising results shown by the VSI suggest that it could be an appropriate candidate for monitoring vegetation structure from the multi-angular satellite remote sensing.

Preprint REVIEW | doi:10.20944/preprints202403.1439.v1

Hepatitis C Virus E1E2 Structure, Diversity, and Implications for Vaccine Development

Brian G. Pierce, Nathaniel Felbinger, Mathew Metcalf, Eric A. Toth, Gilad Ofek, Thomas R. Fuerst

Subject: Biology And Life Sciences, Virology Keywords: HCV E1E2; structure; nanoparticles; vaccine

Online: 25 March 2024 (08:32:56 CET)

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Hepatitis C virus (HCV) is a major medical health burden and leading cause of chronic liver disease and cancer worldwide. More than 58 million people are chronically infected with HCV, with 1.5 million new infections occurring each year. An effective HCV vaccine is a major public health and medical need as recognized by the World Health Organization. However, due to the high variability of the virus and its ability to escape the immune response, HCV rapidly accumulates mutations making a vaccine a formidable challenge. An effective vaccine must elicit broadly neutralizing antibodies (bnAbs) in a consistent fashion. After decades of studies from basic research through clinical development, the antigen of choice is considered to be the E1E2 envelope glycoprotein due to conserved, broadly neutralizing antigenic domains located in the constituent subunits of E1, E2, and the E1E2 heterodimeric complex itself. The challenge has been elicitation of robust humoral and cellular responses leading to broad virus neutralization due to the relatively low immunogenicity of this antigen. In view of this challenge, structure-based vaccine design approaches to stabilize key antigenic domains have been hampered due to the lack of E1E2 atomic-level resolution structures to guide them. Another challenge has been development of a delivery platform in which a multivalent form of the antigen can be presented in order to elicit a more robust anti-HCV immune response. Recent nanoparticle vaccines are gaining prominence in the field due to their ability to facilitate a controlled multivalent presentation and trafficking to lymph nodes, where they can interact with both the cellular and humoral components of the immune system. This review focuses on recent advances in understanding the E1E2 heterodimeric structure to facilitate a rational design approach and the potential for development of a multivalent nanoparticle-based HCV E1E2 vaccine. Both aspects are considered important in the development of an effective HCV vaccine that can effectively address viral diversity and escape.

Preprint ARTICLE | doi:10.20944/preprints202307.1887.v1

Unearthing Soil Structure Dynamics under Long-Term No-Tillage System in Clayey Soils

Kopano Conferance Phefadu, Lawrence Munjonji

Subject: Environmental And Earth Sciences, Soil Science Keywords: Tillage,; texture; structure; VESS; SubVESS

Online: 27 July 2023 (09:35:29 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202305.1525.v1

Modeling Investigation of Groove Effect on the Multipactor of Dielectric-loaded Coaxial Low-pass Filters

Jincheng Shi, Yuchao Zhao, Weixiang Zhou, Bochang Sun, Jinbo Zhang, Dongliang Wang, Ying Liu, Teng Sun, Xiangtian Zhang, Weihao Tie

Subject: Physical Sciences, Applied Physics Keywords: multipactor; groove structure; secondary electron

Online: 22 May 2023 (12:28:36 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202302.0196.v1

SFRRG: A Graph Neural Network Recommendation Model based on Feature and Structure Information

Devon Patterson, John Wilson, Michael Forrow, Tereza Wald

Subject: Computer Science And Mathematics, Information Systems Keywords: Recommendation; GNN; Information; Feature; Structure

Online: 13 February 2023 (03:28:02 CET)

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Preprint ARTICLE | doi:10.20944/preprints202107.0196.v1

Macrocyclic Tetramers – Structural Investigation of Peptide-Peptoid Hybrids

Claudine Herlan, Anna Sonnefeld, Thomas Gloge, Julian Brückel, Luisa Schlee, Claudia Muhle-Goll, Martin Nieger, Stefan Bräse

Subject: Chemistry And Materials Science, Analytical Chemistry Keywords: peptidomimetics; tetramers; macrocycles; spatial structure.

Online: 8 July 2021 (10:59:08 CEST)

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Preprint REVIEW | doi:10.20944/preprints202310.1041.v2

Integration of Plasmonics Structures in Photonics Waveguides: Enabling Novel Electromagnetic Functionalities in Photonic Circuits

Giovanni Magno, Vy Yam, Béatrice Dagens

Subject: Physical Sciences, Optics And Photonics Keywords: plasmonics; photonic integrated circuits; surface plasmon; nanotweezers; couplers; strong coupling; magnetoplasmonics; nanoantennas

Online: 7 November 2023 (12:53:17 CET)

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Preprint REVIEW | doi:10.20944/preprints202208.0213.v2

Towards a Truly General Intermolecular Binding Affinity Calculator for Drug Discovery & Design

Wei Li, Gary Vottevor

Subject: Biology And Life Sciences, Biophysics Keywords: GIBAC; Biophysics; Structural Biology; Drug discovery \& design; Artificial intelligence-integrated drug discovery

Online: 19 October 2023 (13:38:05 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202308.0164.v1

Consciousness as a special case of emergent information

Daniel Boyd

Subject: Social Sciences, Cognitive Science Keywords: Emergence; Information; Consciousness; Integrated Information Theory; Emergent Information Theory; Connectome; Artificial Intelligence

Online: 2 August 2023 (08:36:05 CEST)

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Preprint REVIEW | doi:10.20944/preprints202306.1463.v1

Application of Intelligent Medical Sensing Technology

Jie Fu, Qiya Gao, Shuang Li

Subject: Engineering, Electrical And Electronic Engineering Keywords: Intelligent medical sensing technology; Integrated circuits; Artificial intelligence; Cloud medicine; Health monitoring

Online: 27 June 2023 (12:30:11 CEST)

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Preprint REVIEW | doi:10.20944/preprints202211.0567.v1

Valorization of Lignocellulosic Biomass into Biofuels and Value-Added Products for Sustainable Environment: A Comprehensive Review

Surbhi Sharma, Mei-Ling Tsai, Vishal Sharma, Pei-Pei Sun, Parushi Nargotra, Bijender Kumar Bajaj, Chiu-Wen Chen, Cheng-Di Dong

Subject: Biology And Life Sciences, Biology And Biotechnology Keywords: Keywords: Integrated biorefinery; Circular economy; Lignocellulosic biomass; Pretreatment; Valorization; Enzymes; Biofuels; Biochemicals

Online: 30 November 2022 (08:50:21 CET)

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Preprint ARTICLE | doi:10.20944/preprints202209.0344.v1

International Production and Trade in the IC Industry Based on Complex Network SNA under COVID-19

Chunnan Teng, Yungchih Lien, Homin Chen

Subject: Business, Economics And Management, Business And Management Keywords: SNA; Foreign Trade; Social network analysis; Electronic integrated circuits; UCINET; COVID-19

Online: 22 September 2022 (11:26:03 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202108.0342.v1

On the Operational Utility of Measures of EEG Integrated Information

David Darmon, Tomas Watanabe, Christopher Cellucci, Paul E Rapp

Subject: Social Sciences, Behavior Sciences Keywords: integrated information theory; Lempel-Ziv complexity; multichannel EEGs; Electroencephalography; measures of consciousness

Online: 16 August 2021 (13:52:06 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202106.0084.v1

Disease Susceptibility of Interspecific Cold-hardy Grape Cultivars in Northeastern U.S.A.

Ann L Hazelrigg, Terence L Bradshaw, Gabriella S. Maia

Subject: Biology And Life Sciences, Anatomy And Physiology Keywords: Vitis spp.; interspecific hybrid grapes; cultivar evaluation; Integrated Pest Management; disease resistance.

Online: 2 June 2021 (15:01:26 CEST)

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Preprint REVIEW | doi:10.20944/preprints202010.0053.v1

Building a High Customer Experience Management Organization: Towards Customer-Centricity

Lamin B. Ceesay

Subject: Business, Economics And Management, Accounting And Taxation Keywords: customer experience; customer-centricity; customer experience design; and integrated customer experience strategy

Online: 5 October 2020 (08:14:04 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202007.0170.v1

Spanish Validation of the User Reported Measure of Care Coordination Questionnaire for Older People with Complex, Chronic Conditions

Ester Risco, Gloria Sauch Valmaña, Anna Albero, Nihan Acar-Denizli, Adela Zabalegui, Belchin Adriyanov kostov, Paloma Amil, Albert Alonso, Núria Fabrellas

Subject: Public Health And Healthcare, Nursing Keywords: Integrated Care; Social Care; Health Care; Older People; Comorbidity: Person Centered Care

Online: 9 July 2020 (06:23:49 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202005.0437.v1

International Undergraduate Medical Student in China and the Potentiality of Using PBL Method in the Integrated Organ/System Curriculum

S.Fakhruddin Masse, Huibing Tan

Subject: Social Sciences, Education Keywords: medical education; pedagogy; international student; problem-based learning; integrated organ/system; China

Online: 27 May 2020 (04:35:20 CEST)

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Preprint ARTICLE | doi:10.20944/preprints201808.0419.v1

Corporate Board Characteristics and Environmental Disclosure Quantity: A Comparative Analysis of Traditional and Integrated Reporting Evidence

Ndubuisi Odoemelam, Grace Ofoegbu

Subject: Business, Economics And Management, Accounting And Taxation Keywords: Corporate board characteristics; environmental disclosure; Traditional and integrated frameworks; South Africa; Nigeria

Online: 23 August 2018 (15:51:10 CEST)

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Abstract: The aim of this study was to compare the influence of corporate board characteristics on the extent of environmental disclosure quantity of listed firms in two leading emerging economies in Africa, South Africa (integrated reporting framework) and Nigeria (traditional reporting framework). Methods: The sample was comprised of 303 firms including environmentally sensitive companies purposively selected for content analysis study in South Africa (213) and Nigeria (90). We used both descriptive, multivariate and regression models to comparatively analyze the differences about corporate board characteristics as determinants of the extent of their environmental disclosure quantity. Results: The results reveal a more significant positive association between board characteristics and environmental disclosure in South Africa and less relevant association in Nigeria. Also, the results support that board independence arrangement may serve as bonding mechanisms in weak reporting environments, suggesting a substitutive relationship between board independence and the regulatory framework. Quiet revealing a board with environmental committee show a higher tendency to be ecologic transparent in both countries. However, in a traditional reporting framework, the environmental committee is not enough; its effect was insignificant and highly significant in the integrated reporting framework. Further revealed is the significant positive effect of industry membership influence on environmental disclosure. In all estimated models of South Africa sample show that 45% of environmentally sensitive industries significantly influence environmental disclosure, while 51% is environmentally polluting industries in Nigeria show less concern on environmental disclosure. Interestingly, Audit firm size (Big4) positively and statistically significantly associated with overall environmental reporting in both countries. The results are consistent with stakeholder theory, agency theory, institutional and legitimacy theory suggesting that a strong board size, independent members of the board with auditing experience, the active environmental committee in conjunction with solid audit reputation may reduce information asymmetry. Our findings will be helpful for policymakers and other regulators who are interested in environmental impact reporting.

Preprint ARTICLE | doi:10.20944/preprints201803.0086.v1

IWRM as a System Approach to Water Security: Evidence from the Awash River Basin of Ethiopia

Reta Hailu, Degefa Tolossa, Getnet Alemu

Subject: Environmental And Earth Sciences, Water Science And Technology Keywords: Integrated Water Resources Management (IWRM); system thinking; water security; Awash basin; Ethiopia

Online: 12 March 2018 (07:18:33 CET)

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Preprint ARTICLE | doi:10.20944/preprints201710.0132.v1

Accelerated Benders’ Decomposition for Integrated Forward/Reverse Logistics Network Design under Uncertainty

Vahab Vahdat, Mohammad Ali vahdatzad

Subject: Engineering, Industrial And Manufacturing Engineering Keywords: integrated forward/reverse logistics network; accelerated benders’ decomposition; two-stage stochastic programming

Online: 20 October 2017 (03:07:28 CEST)

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Preprint ARTICLE | doi:10.20944/preprints201710.0028.v1

Security-Constrained Optimal Dispatch of Combined Natural Gas and Electricity Networks Using Genetic Algorithms

Denis C. L. Costa, João Paulo Vieira, Marcus V. A. Nunes

Subject: Engineering, Energy And Fuel Technology Keywords: Integrated Electric Power and Natural Gas Network, Optimal Power Flow, Genetic Algorithm.

Online: 5 October 2017 (09:41:12 CEST)

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Preprint ARTICLE | doi:10.20944/preprints201709.0021.v1

Comparing Markov Chain Samplers for Molecular Simulation

Robert D. Skeel, Youhan Fang

Subject: Physical Sciences, Atomic And Molecular Physics Keywords: Markov chain Monte Carlo; stochastic dynamics integrators; decorrelation time; integrated autocorrelation time

Online: 7 September 2017 (03:43:35 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202404.0576.v1

A Reversible Spherical Geometric Conversion of Protein Backbone Structure Coordinate Matrix to Three Independent Vectors of ρ, θ and φ

Wei Li

Subject: Biology And Life Sciences, Biophysics Keywords: Protein structure predicting; Cartesian coordinate system; Spherical coordinate system; Protein backbone structure coordinate matrix

Online: 8 April 2024 (15:00:25 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202402.0328.v1

A Coupled Finite-Boundary Element Method for Efficient Dynamic Structure-Soil-Structure Interaction Modeling

Parham Azhir, Jafar Asgari Marnani, Mehdi Panji, Mohammad Sadegh Rohanimanesh

Subject: Engineering, Civil Engineering Keywords: Structure-Soil-Structure Interaction; Boundary Element Method; Finite Element Method; Numerical Modeling; Computational Efficiency

Online: 6 February 2024 (05:15:38 CET)

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Preprint ARTICLE | doi:10.20944/preprints202310.0047.v1

Three Dimensional Hydroelasticity of Multi-connected Modular Offshore Floating Solar Photovoltaic Farm

Zhi Yung Tay

Subject: Engineering, Civil Engineering Keywords: hydroelastic response; offshore floating solar photovoltaic farm; very large floating structure; modular floating structure

Online: 2 October 2023 (06:35:30 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202309.1544.v1

Graded Triply Periodic Minimal Surface Structures with Lightweight, High-Strength and Sound Absorption Produced by Laser Powder Bed Fusion

Mingkang Zhang, Chang Liu, Mingjian Deng, Yuhao Li, Jinwei Li, Di Wang

Subject: Physical Sciences, Acoustics Keywords: triply periodic minimal surface; porous structure; laser powder bed fusion; graded structure; sound absorption

Online: 25 September 2023 (04:47:37 CEST)

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Working Paper ARTICLE

Towards Room-Temperature Superconductivity

Jacob Szeftel, Nicolas Sandeau, Michel Abou Ghantous, Muhammad El Saba

Subject: Physical Sciences, Acoustics Keywords: room-temperature superconductivity; thermodynamics; Electronic structure; Effects of material synthesis; crystal structure; chemical composition

Online: 4 February 2021 (11:20:12 CET)

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Working Paper ARTICLE

Period Doubling Phenomenon as the Origin of Electron Properties

Ari Lehto

Subject: Physical Sciences, Atomic And Molecular Physics Keywords: period doubling; electron structure; elementary charge; electron magnetic moment; fine structure constant; Planck scale; Standard Model

Online: 20 August 2020 (04:08:27 CEST)

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Preprint ARTICLE | doi:10.20944/preprints201901.0160.v2

Flow-Induced Stresses and Displacements in Jointed Concrete Pipes, Installed by Pipe Jacking Method

Moses Karakouzian, Mehrdad Karami, Mohammad Nazari-Sharabian, Sajjad Ahmad

Subject: Engineering, Civil Engineering Keywords: fluid-structure interaction; soil-structure interaction; transient flow; pipe jacking; numerical modeling; abaqus FEA

Online: 17 January 2019 (05:02:55 CET)

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Preprint ARTICLE | doi:10.20944/preprints201904.0154.v1

Structural Change Analysis of Cerianite in Weathered Residual Rare Earth Ore by Mechanochemical Reduction Using X-ray Absorption Fine Structure

Tatsuya Kato, Yuki Tsunazawa, Wenying Liu, Chiharu Tokoro

Subject: Engineering, Chemical Engineering Keywords: oxygen vacancy; extended x-ray absorption fine structure; high-intensity grinding; local structure; quantum effect

Online: 13 April 2019 (05:18:11 CEST)

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Preprint ARTICLE | doi:10.20944/preprints201904.0016.v1

Machine Learning Approaches for Designing Meso-scale Structure of Li-ion battery Electrode

Yoichi Takagishi, Takumi Yamanaka, Tatsuya Yamaue

Subject: Chemistry And Materials Science, Electrochemistry Keywords: Li-ion battery; electrode; porous structure; virtual structure; machine learning; simulation; physico-chemical model; optimization

Online: 1 April 2019 (13:35:13 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202403.1710.v1

Beyond Multidimensional Vulnerability Approach: A Triple Network Notion for Urban Cohesion in At-Risk Neighborhoods of Jaen’s Historic Center

Juan L. Rivas-Navarro, Belén Bravo-Rodríguez

Subject: Social Sciences, Urban Studies And Planning Keywords: urban vulnerability; integrated urban regeneration; social cohesion; public space; sustainable planning; urban environment

Online: 28 March 2024 (06:56:42 CET)

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Preprint ARTICLE | doi:10.20944/preprints202310.0138.v1

Multi-Frequency Differential Absorption LIDAR (DIAL) System for Aerosol and Cloud Retrievals of CO2/H2O and CH4/H2O

Jasper R Stroud, Gerd A Wagner, David F Plusquellic

Subject: Environmental And Earth Sciences, Atmospheric Science And Meteorology Keywords: DIAL; differential absorption lidar; IPDA; integrated path differential absorption LIDAR; cloud aerosol retrievals

Online: 3 October 2023 (09:35:01 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202307.0897.v1

Investigation on the Power Consumption of Digital-Based Analog Amplifiers

Anna Richelli, Paolo Faustini, Andrea Rosa, Luigi Colalongo

Subject: Engineering, Electrical And Electronic Engineering Keywords: Digital-based amplifiers; analog integrated circuits; amplifiers; ultra low voltage; ultra low power

Online: 13 July 2023 (10:57:54 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202307.0579.v1

A Richness Estimator Based on Integrated Data

Chun-Huo Chiu

Subject: Environmental And Earth Sciences, Ecology Keywords: Chao’s lower bound estimator; Good-Turing frequency formula; Integrated data; singleton; doubleton; tripleton

Online: 10 July 2023 (09:05:09 CEST)

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Preprint REVIEW | doi:10.20944/preprints202306.0726.v1

Water Resources Management under Climate Change: A Review

Marzia Ciampittiello, Aldo Marchetto, Angela Boggero

Subject: Environmental And Earth Sciences, Waste Management And Disposal Keywords: Climate change; integrated water research management; water resources; nature based solutions; groundwater management

Online: 9 June 2023 (13:17:32 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202305.0277.v1

Upconversion Nanoparticle-Based Fluorescent Film for Distributed Temperature Monitoring of Mobile Phone Integrated Chips

Hanyang Li, Miao Yu, Jichun Dai, Gaoqian Zhou, Jiapeng Sun

Subject: Physical Sciences, Optics And Photonics Keywords: upconversion nanomaterials; ratiometric thermometry; Temperature sensing; Polymer composite film; Integrated chip temperature measurement

Online: 5 May 2023 (02:43:29 CEST)

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Preprint REVIEW | doi:10.20944/preprints202301.0016.v1

Integrated Optical Frequency Microcomb Applications

David Moss

Subject: Physical Sciences, Optics And Photonics Keywords: Integrated photonics; microcombs; microwave photonics; optical communications; precision measurements; neuromorphic computing; quantum optics

Online: 3 January 2023 (08:00:03 CET)

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Preprint ARTICLE | doi:10.20944/preprints202212.0094.v1

Gut Microbial Perturbation and Host Response Induces Redox Pathway Upregulation along the Gut-liver Axis during Giardiasis in C57BL/6J Mouse Model

Avinash V Karpe, Melanie L Hutton, Steven J Mileto, Meagan L James, Chris Evans, Amol B Ghodke, Rohan M Shah, Suzanne S Metcalfe, Jian-Wei Liu, Tom Walsh, Dena Lyras, Enzo A Palombo, David J Beale

Subject: Chemistry And Materials Science, Analytical Chemistry Keywords: host-parasite interactions; systems biology; giardiasis; gut-liver axis; integrated multiomics; metabolic pathways

Online: 6 December 2022 (07:39:57 CET)

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Apicomplexan infections, such as giardiasis and cryptosporidiosis, negatively impact a considerable proportion of human and commercial livestock populations. Despite this, the molecular mecha-nisms of disease, particularly the effect on the body beyond the gastrointestinal tract, are still poorly understood. To highlight host-parasite-microbiome biochemical interactions, we utilised integrated metabolomics-16S rRNA genomics and metabolomics-proteomics approaches in a C57BL/6J mouse model of giardiasis and compared these to Cryptosporidium and uropathogenic Escherichia coli (UPEC) infections. Comprehensive samples (faeces, blood, liver, and luminal contents from duo-denum, jejunum, ileum, caecum and colon) were collected 10 days post infection and subjected to proteome and metabolome analysis by liquid and gas chromatographic mass-spectrometry, re-spectively. Microbial populations in faeces and luminal washes were examined using 16S rRNA metagenomics. Proteome-metabolome analyses indicated that 12 and 16 key pathways were sig-nificantly altered in the gut and liver, respectively, during giardiasis with respect to other infections. Energy pathways including glycolysis and supporting pathways of glyoxylate and dicarboxylate metabolism, and redox pathway of glutathione metabolism, were upregulated in small intestinal luminal contents and the liver during giardiasis. Metabolomics-16S rRNA genetics integration in-dicated that populations of three bacterial families –Autopobiaceae (Up), Desulfovibrionaceae (Up) and Akkermanasiaceae (Down) – were most significantly affected across the gut during giardiasis, causing upregulated glycolysis and short-chained fatty acid (SCFA) metabolism. In particular, the perturbed Akkermanasiaceae population seemed to cause oxidative stress responses along the gut-liver axis. Overall, the systems biology approach applied in this study highlighted that the effects of host-parasite-microbiome biochemical interactions extended beyond the gut ecosystem to the gut-liver axis. These findings form the first steps in a comprehensive comparison to ascertain the major molecular and biochemical contributors of host-parasite interactions and contribute towards the development of biomarker discovery and precision health solutions for apicomplexan infections.

Preprint REVIEW | doi:10.20944/preprints202205.0074.v1

A Review of Future Household Waste Management for Sustainable Environment in Malaysian Cities

Kin Meng Cheng, Jia Yue Tan, Shen Yuong Wong, Ah Choo Koo, Elyna Amir Sharji

Subject: Environmental And Earth Sciences, Waste Management And Disposal Keywords: Household waste; household waste management; sustainable city; integrated waste management model; Malaysia cities

Online: 6 May 2022 (10:27:56 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202205.0063.v1

Determinants for Deployment of Climate-Smart Integrated Pest Management Practices: A Meta-Analysis Approach

Haruna Sekabira, Ghislain T. Tepa-Yotto, Rousseau Djouaka, Victor Clottey, Christopher Gaitu, Manuele Tamò, Yusuf Kaweesa, Stanley Peter Ddungu

Subject: Environmental And Earth Sciences, Environmental Science Keywords: socio-economic determinants; agricultural technologies; climate-smart; integrated pest management technologies (CS-IPM)

Online: 6 May 2022 (08:41:24 CEST)

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Following the development and dissemination of new climate-smart agricultural technologies to farmers globally, there has been an increase in the number of socio-economic studies on the adoption of climate-smart integrated pests’ management (CS-IPM) technologies over the years. In this study, we review empirical evidence on adoption determinants of CS-IPM technologies and identify possible science-policy interfaces. Generally, our review shows that socioeconomic and institutional factors are influential in shaping CS-IPM adoption decisions of farmers. More specifically, income was found to positively influence the adoption of CS-IPM technologies while land size owned influences CS-IPM adoption negatively. Registered land tenure (registered secure rights) positively influences CS-IPM technologies’ adoption, implying that efficient land markets that enable competitive and fair distribution and access to land, more so by the vulnerable but efficient smallholder producers do indeed increase the adoption of CS-IPMs technologies. Social capital, achieved via farmers’ organizations is also central in fostering CS-IPM technologies’ adoption, just as markets reforms that minimize market failures regarding access to credit, labor, and agricultural information, which could indirectly hinder farmers’ use of CS-IPM practices. Functional extension systems that improve farmers’ awareness of CS-IPM do also improve CS-IPM technologies’ adoption. However, the adoption of CS-IPM technologies in Ghana and Benin is slow-paced because of factors like lack of access to farm inputs that facilitate uptake of these technologies, lack of credit facilities, and limited extension services among others. Interestingly, our review confirms that CS-IPM technologies do indeed reduce and minimize the intensity of pesticide usage and foster ecosystem (environmental and human) health. Therefore, this review unearths strategic determinants of CS-IPM adoption and makes fundamental guidance around climate-smart innovations transfer and environmental policies that should be prioritized to curb environmental pollution and ensure agricultural ecosystems’ sustainability.

Preprint REVIEW | doi:10.20944/preprints202009.0276.v1

Biosynthesis of Lemongrass Essential Oil and the Underlying Mechanism for Its Insecticidal Activity

Mohammad Mukarram, M. Masroor A. Khan, Andleeb Zehra, Sadaf Choudhary, Tariq Aftab, M. Naeem

Subject: Biology And Life Sciences, Plant Sciences Keywords: Citral; essential oil; integrated pest management; insect-repellent; lemongrass; MEP pathway; mevalonate pathway

Online: 13 September 2020 (11:30:41 CEST)

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Preprint ARTICLE | doi:10.20944/preprints201905.0331.v1

On the Role of Electric Vehicles towards Low-Carbon Energy Systems: Italy and Germany in Comparison

Sara Bellocchi, Kai Klöckner, Michele Manno, Michel Noussan, Michela Vellini

Subject: Engineering, Energy And Fuel Technology Keywords: large-scale RES; curtailments; electric vehicles; EnergyPLAN; integrated energy systems analysis; CO2 emissions

Online: 28 May 2019 (10:33:27 CEST)

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Preprint ARTICLE | doi:10.20944/preprints201810.0119.v1

Low-Loss Lithium Niobate on Insulator (LNOI) Waveguides of a 10 cm-Length and a Sub-Nanometer Surface Roughness

Rongbo Wu, Min Wang, Jian Xu, Jia Qi, Wei Chu, Zhiwei Fang, Jianhao Zhang, Junxia Zhou, Lingling Qiao, Zhifang Chai, Jintian Lin, Ya Cheng

Subject: Physical Sciences, Optics And Photonics Keywords: lithium niobate; waveguide; photonic integrated circuit; propagation loss; optical lithography; chemo-mechanical polishing

Online: 7 October 2018 (10:34:27 CEST)

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Preprint ARTICLE | doi:10.20944/preprints201809.0581.v1

Chemical and Non-Chemical Solutions for Managing Twospotted Spider Mite, Western Tarnished Plant Bug, and Other Arthropod Pests in Strawberries

Surendra K. Dara, David Peck, Dave Murray

Subject: Biology And Life Sciences, Insect Science Keywords: Frankliniella occidentalis; Lygus hesperus; Trialeurodes vaporariorum; Tetranychus urticae; entomopathogenic fungi; integrated pest management

Online: 29 September 2018 (05:33:45 CEST)

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Preprint ARTICLE | doi:10.20944/preprints201803.0274.v1

What’s Conventional and what’s Special in a Reservoir Study for Underground Gas Storage

Francesca Verga

Subject: Engineering, Energy And Fuel Technology Keywords: underground gas storage; delta-pressuring; integrated analysis; UGS characterization; UGS management; UGS monitoring

Online: 5 April 2018 (15:12:09 CEST)

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Preprint COMMUNICATION | doi:10.20944/preprints201804.0045.v1

Evidence Decision-Making Policy Practice in Emerging Pandemics and Epidemics Threats Preparedness and Response Operations in Africa

Ernest Tambo, Ghislaine Madjou, Christopher Khayeka−Wandabwa, Pascal DJ Chuisseu, Oluwasogo A. Olalubi, Jeanne Y. Ngogang

Subject: Medicine And Pharmacology, Other Keywords: evidence; poverty; health, financing; allocation; integrated; participation partnership; responsibility; infectious diseases; pandemics; Africa

Online: 4 April 2018 (05:33:16 CEST)

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Quality evidence-based decisions and strategies are critical and valuable tools in strengthening health systems policies, strategic priorities action plans and comprehensive care delivery management. Our finding showed that there is scarcity of local/national and internal effective evidence-based and management strategies for informed decision making based on the disease or health epidemics nature, extend, ecological and geo-location of pandemics and epidemics crises burden and impacts. Evidence-based programs or projects are crucial in evolving pandemics and/or (Ebola, meningitis, Cholera and influenza) epidemics persistent morbidity and mortality/ case fatality reduction or prevention; as well as on poverty and inequity alleviation within the vulnerable population and citizenry over time. This paper assesses implications of evidence-based on health systems surveillance and monitoring systems, preparedness and emergency response gaps and needs in improving care delivery uptake and usefulness, coverage and effectiveness in Africa. Furthermore, the article advocates for quality, access to and uptake of knowledge-based policy-decision making and practice improvements in building efficient and standardized surveillance, preparedness and response approaches. Also, in enriching data sharing and inclusiveness through understanding the links between poverty, poor health and inequited related emerging infectious diseases epidemics in Africa. Leveraging on cumulative lessons learnt experiences and innovations in integrating participatory knowledge-based policies and approaches is paramount in fostering vulnerable population awareness and engagement, skills empowerment collaborative productivity and sustainable healthy solutions and measures. Strengthening new partnerships, alliances, and networks requires collaborative and quality evidence policy decisions, appropriate and reliable monitoring and evaluation systems approaches and strategies in improving local preparedness and emergency response capabilities against future emerging infectious diseases epidemics and fast-tracking poverty alleviation knowledge-based livelihoods and health solutions for impact. Furthermore, integrated, participative partnerships and collaborative responsibilities, cost effective and reliable evidence health financing and budget allocation, and targeted capacity development aiming at reducing and averting the burden of poverty related emerging threats and epidemics preparedness and response programs in African countries.

Preprint ARTICLE | doi:10.20944/preprints202403.0642.v1

Microstructural Approach Application for Morphological Changes Determination of Grape during Drying

Wijitha Senadeera, Jasmine Banks, Giuseppina Adiletta, Kate Brewer

Subject: Engineering, Other Keywords: Grape; drying; Micro-structure; SEM; Algorithm

Online: 11 March 2024 (17:58:37 CET)

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Preprint ARTICLE | doi:10.20944/preprints202402.0939.v1

Structure and Luminescent Properties of Niobium Modified ZnO-B2O3:Eu3+ Glass

Reni Iordanova, Margarita Milanova, Aneliya Yordanova, Lyubomir Aleksandrov, Nikolay Nedylkov, Rosica Kukeva, Petia Petrova

Subject: Chemistry And Materials Science, Materials Science And Technology Keywords: glass structure; europium; IR; photoluminescence; density

Online: 19 February 2024 (11:48:45 CET)

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Preprint ARTICLE | doi:10.20944/preprints202311.0445.v1

Enhanced Electrochemical Performance of LaMnO₃ Nanoparticles by Ca/Sr Doping

Jun-han Zheng, Hong-Quan Zhao, Xu Guo, Xiao-Yun Jin, Lei Wang, Songtao Dong, Jian Chen

Subject: Chemistry And Materials Science, Materials Science And Technology Keywords: perovskite; crystal structure; electrochemical performance; LaMnO3

Online: 8 November 2023 (01:31:22 CET)

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Preprint REVIEW | doi:10.20944/preprints202311.0147.v1

Structure Overview of Herpesvirus Tegument Proteins

Hui-Ping He, Song Gao

Subject: Biology And Life Sciences, Virology Keywords: Herpesviruses; Tegument proteins; Structure; Viral pathogenesis

Online: 2 November 2023 (10:13:22 CET)

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Preprint COMMUNICATION | doi:10.20944/preprints202309.1634.v1

Super Typhoon Saola (2309) affecting Hong Kong in September 2023–Forecasting Aspect

P.W. Chan, Y.H. He, Y.S. Lui

Subject: Environmental And Earth Sciences, Atmospheric Science And Meteorology Keywords: tropical cyclone; track; intensity; wind structure

Online: 25 September 2023 (09:32:43 CEST)

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Preprint REVIEW | doi:10.20944/preprints202308.1015.v1

Heterologous Interactions with Galectins and Chemokines and Their Functional Consequences

Kevin H. Henry Mayo

Subject: Biology And Life Sciences, Biochemistry And Molecular Biology Keywords: galectin; chemokine; structure; function; NMR; modeling

Online: 14 August 2023 (10:51:46 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202307.0713.v1

Al-Doped Octahedral Cu2O Nanocrystal for Electrocatalytic CO2 Reduction to Produce Ethylene

Sanxiu LI, Xuelan Sha, Xiafei Gao, Juan Peng

Subject: Chemistry And Materials Science, Electrochemistry Keywords: electrocatalysis; electronic structure; Faradaic efficiency; ethylene

Online: 11 July 2023 (11:33:37 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202306.1496.v1

The Composition, Structure and Functionalities of Prolamins from Highland Barley

Jinjin Xing, Wenhui Zhang, Zhaomin Li, Pengjie Wang

Subject: Chemistry And Materials Science, Food Chemistry Keywords: prolamins; highland barley; composition; structure; functionalities

Online: 21 June 2023 (07:43:07 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202305.1234.v1

Butterflies of the Neotropical Seasonally Dry Forest of Montes de María (Sucre, Colombia): What do they Tell us about the Intermediate Disturbance Hypothesis?

Yarlenis L Mercado-Gómez, Jorge D Mercado-Gómez, Carlos E Giraldo-Sánchez

Subject: Biology And Life Sciences, Ecology, Evolution, Behavior And Systematics Keywords: structure; diversity; anthropic disturbance; conservation; Lepidoptera

Online: 17 May 2023 (10:38:26 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202305.0163.v1

The Interaction of Ribosomal Protein L22 with Epstein-Barr Virus-Encoded RNA-1 in Intracellular Transport

Zubaida Hassan, Pretty S. Philip, Bincy Baby, M. Kalim Akhtar, Anatoliy Shmygol, Gulfaraz Khan

Subject: Biology And Life Sciences, Immunology And Microbiology Keywords: EBER1; Intracellular transport; RPL22; Secretion; Structure

Online: 4 May 2023 (02:48:03 CEST)

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Preprint REVIEW | doi:10.20944/preprints202209.0050.v1

An Overview of the Infectious Cycle of Bunyaviruses

Hani Boshra

Subject: Biology And Life Sciences, Virology Keywords: bunyavirus; structure; genomics; immune response; review

Online: 5 September 2022 (07:49:30 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202207.0123.v1

Discontinuity in the Electronic Structure and Magnetic Order of β-Co_1+xGa₁-_x

Gerhard H. Fecher

Subject: Chemistry And Materials Science, Materials Science And Technology Keywords: CoGa; electronic structure; magnetism; binary alloys

Online: 7 July 2022 (09:44:18 CEST)

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Preprint COMMUNICATION | doi:10.20944/preprints202112.0492.v1

Secondary Structure and X-Ray Crystallographic Analysis of the Glideosome-Associated Connector (GAC) from Toxoplasma gondii

Amit Kumar, Xu Zhang, Oscar Vadas, Fisentzos Stylianou, Nicolas Dos Santos Pacheco, Sarah Rouse, Marc Morgan, Dominique Soldati-Favre, Stephen Matthews

Subject: Biology And Life Sciences, Biochemistry And Molecular Biology Keywords: glideosome-associated connector; protein; crystallography; structure

Online: 30 December 2021 (17:13:26 CET)

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Preprint ARTICLE | doi:10.20944/preprints202008.0325.v1

Structural Characterization of Graphite Nanoplatelets Synthesized from Graphite Flakes

HANI MANSSOR ALBETRAN

Subject: Chemistry And Materials Science, Nanotechnology Keywords: Carbon; Crystal structure; Graphene; Graphite; Nanoplatelet.

Online: 14 August 2020 (11:58:53 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202006.0184.v1

Single Amino Acid Variant (SAV) Percentage and Monomer Modeling of Spike Protein of SARS-CoV-2 in Jordan

Walid Al-Zyoud, Hazem Haddad, Ramzi Foudeh

Subject: Biology And Life Sciences, Biochemistry And Molecular Biology Keywords: COVID-19; SARS; spike; variants; structure

Online: 14 June 2020 (16:00:35 CEST)

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Spike protein is the surface glycoprotein of the severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2) necessary for the entry of the virus via the transmembrane receptors of the human endothelial cells of the respiratoty system for the virus to be engulfed causing COVID-19 disease after priming by type II transmembrane protease TMPRSS2 and then binding with the angiotensin-converting enzyme 2 (ACE2). Therefore, mutations and amino acid variants analysis are essential in understanding the mechanism of binding of spike protein with its receptor to have an insights on possibilities to design a peptide or nucleotide-based vaccine for COVID-19. Here, we employed Iterative Threading Assembly Refinement (I-TASSER) and Multiple Alignment using Fast Fourier Transform (MAFFT) to predict the three-dimensional monomer structure of spike protein of SARS-CoV-2 and to analyze the amino acid variants for protein sequences from GISAID database for samples collected from Jordan in a try to find an explanation for the low confirmed number of COVID-19 in Jordan. Our Protein Homology/analogY Recognition Engine V 2.0 (Phyre2) findings showed four single amino acid variants (SAV) found in 20 samples of SARS-CoV-2. What is equal to 5% of samples showed tyrosine deletion at Y144 located in the SARS-CoV-like_Spike_S1_NTD (N terminal domain), 62% showed aspartate substitution to glycine at D614G located in the SARS-CoV-2_Spike_S1_RBD (spike recognition binding site), 5% showed aspartate substitution to tyrosine at D1139Y and 5% showed glycine substitution to serine at G1167S both located in the Corona_S2 domain. The findings have shown lower mutational sensitivity in all variants that might not affect the function of spike glycoprotein except for D614G, which has the highest mutational sensitivity score (5 out of 9) indicating a higher likelihood to affect the function of the spike protein. This might suggest, in general, a reduced transmitability of SARS-CoV-2 in Jordan.

Preprint ARTICLE | doi:10.20944/preprints201907.0257.v2

The Zero Energy Idea in District. Application of a Methodological Approach in the Case Study of Epinlieu (Mons)

Sesil KOUTRA, Claire Pagnoule, Fivos Nikolaos Galatoulas, Ali Bagheri, Thomas Waroux, Vincent Becue, Christos S. Ioakimidis

Subject: Social Sciences, Sociology Keywords: Case study; District; Energy; Structure; Zero

Online: 24 July 2019 (11:53:34 CEST)

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Preprint ARTICLE | doi:10.20944/preprints201903.0041.v1

Functional RNA Structures in the 3'UTR of Tick-Borne, Insect-Specific and No-Known-Vector Flaviviruses

Roman Ochsenreiter, Ivo L. Hofacker, Michael T. Wolfinger

Subject: Biology And Life Sciences, Virology Keywords: Flavivirus; non-coding RNA; secondary structure

Online: 4 March 2019 (10:37:46 CET)

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Preprint ARTICLE | doi:10.20944/preprints201901.0198.v1

Dark Proteome Database: Studies on Dark Proteins

Nelson Perdigão

Subject: Computer Science And Mathematics, Information Systems Keywords: Dark Proteome, Molecular Structure, Homology Modelling

Online: 21 January 2019 (08:50:48 CET)

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Preprint ARTICLE | doi:10.20944/preprints201811.0238.v1

Victimization and Social Structure: The Case of Spain in 1999 and 2016

Gonzalo Herranz de Rafael, Juan Sebastián Fernández-Prados

Subject: Social Sciences, Sociology Keywords: victimization; lifestyles; crime; social structure; Spain

Online: 9 November 2018 (04:11:19 CET)

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Preprint ARTICLE | doi:10.20944/preprints201807.0479.v1

CEO's Traits, Dynamic Compensation and Capital Structure

Wei Ye, Yong Zhang

Subject: Business, Economics And Management, Finance Keywords: Managerial triats; Dynamic compensation; capital structure

Online: 25 July 2018 (11:45:27 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202402.0960.v1

Bridging the Gap: Exploring Interpretability in Deep Learning Models for Brain Tumor Classification from MRI Images

Wandile Nhlapho, Marcellin Atemkeng, Yusuf Brima, Jean-Claude Ndogmo

Subject: Computer Science And Mathematics, Artificial Intelligence And Machine Learning Keywords: transfer learning; deep learning; brain tumor classification; explanability and interpretability; Grad-Cam++; integrated gradients

Online: 19 February 2024 (10:21:08 CET)

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Preprint ARTICLE | doi:10.20944/preprints202309.0187.v1

Inhibition of GCN2 Reveals Synergy with Cell-Cycle Regulation and Proteostasis

Gregory Gauthier-Coles, Farid Rahimi, Angelika Bröer, Stefan Bröer

Subject: Medicine And Pharmacology, Pharmacology And Toxicology Keywords: integrated stress response; amino acid; PERK; cyclin-dependent kinases; cell cycle; amino acid transport

Online: 5 September 2023 (05:00:11 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202308.0147.v1

Comparison of Conventional and Organic Wines Produced in Kutnohorsk Region (Czech Republic)

Dani Dordevic, Ludmila Kalcakova, Anna Zackova, Sanja Ćavar-Zeljković, Simona Dordevic, Bohuslava Tremlová

Subject: Chemistry And Materials Science, Food Chemistry Keywords: antioxidant capacity; integrated viticulture; organic viticulture; polyphenols; Pinot Noir; Riesling; sacharides; sulfur dioxide; vitamins

Online: 2 August 2023 (10:29:00 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202303.0425.v1

Conditions for the Broad Application of Prospective Life Cycle Inventory Databases

Bernhard Steubing, Angelica Mendoza Beltran, Romain Sacchi

Subject: Medicine And Pharmacology, Epidemiology And Infectious Diseases Keywords: prospective life cycle assessment; scenarios; future background system; ex-ante LCA; integrated assessment models

Online: 24 March 2023 (04:11:41 CET)

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Preprint ARTICLE | doi:10.20944/preprints202302.0288.v1

Design and Fabrication of a Fully-Integrated, Miniaturised Fluidic System for the Analysis of Enzyme Kinetics

Andreas Tsiamis, Anthony Buchoux, Stephen T. Mahon, Anthony J. Walton, Stewart Smith, David J. Clarke, Adam A. Stokes

Subject: Engineering, Control And Systems Engineering Keywords: sensors; fluidics; integration; lab-on-a-chip; integrated devices; miniaturised total analysis system; optofluidics.

Online: 17 February 2023 (02:00:15 CET)

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Preprint ARTICLE | doi:10.20944/preprints202301.0422.v1

Effects of Herbicide Glyphosate on Fitness Attributes of Zygogramma bicolorata Pallister

Shalini Aryan, R. K. Gupta, R. S. Bandral, S. K. Singh, Susheel Sharma, S. K. Gupta, Umer Basu, Shafat Ahamad Ahanger

Subject: Biology And Life Sciences, Plant Sciences Keywords: Biological control; fitness attributes; glyphosate; Herbicide; insect; integrated weed management; Parthenium; Zygogramma bicolorata; weed

Online: 24 January 2023 (03:31:54 CET)

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Preprint ARTICLE | doi:10.20944/preprints202211.0054.v1

Nature-Based Solutions Are Critical for Putting Brazil on Track Towards Net Zero

Aline Soterroni, Mariana Império, Marluce Scarabello, Nathalie Seddon, Michael Obersteiner, Pedro Rochedo, Roberto Schaeffer, Pedro Andrade, Fernando Ramos, Tasso Azevedo, Jean Ometto, Petr Havlik, Ane Alencar

Subject: Environmental And Earth Sciences, Environmental Science Keywords: Brazil's climate pledges; net-zero emissions; nature-based solutions; mitigation potentials; integrated assessment modelling

Online: 2 November 2022 (10:55:25 CET)

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Preprint ARTICLE | doi:10.20944/preprints202202.0148.v1

Defining the Challenges - Identifying the Key Poisoning Elements to be Separated in a Future Integrated Molten Salt Fast Reactor Clean-up System for iMAGINE

Bruno Merk, Anna Detkina, Dzianis Litskevich, Michael Drury, Omid Noorikalkhoran, Gregory Cartland-Glover, Leon Petit, Stefano Rolfo, Justin P Elliott, Andrew R Mount

Subject: Engineering, Energy And Fuel Technology Keywords: nuclear; nuclaer reactors; nucaler chemistry; molten salt; molten salt reactors; integrated fuel cycle; reporcessing

Online: 10 February 2022 (10:47:09 CET)

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Preprint ARTICLE | doi:10.20944/preprints202201.0455.v1

Impact of Biomass Transformation Efficiency on the Energy Consumption Pattern of the Building Sector

Joseph Ebako

Subject: Engineering, Energy And Fuel Technology Keywords: energy modeling; biomass transformation efficiency; global change assessment model; integrated assessment model; cooking fuel

Online: 31 January 2022 (12:45:00 CET)

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Preprint ARTICLE | doi:10.20944/preprints202105.0466.v1

Dye-Sensitized Solar Cell for Building-Integrated Photovoltaic (BIPV) Applications

Marek Szindler, Magdalena M Szindler, Aleksandra Drygała, Krzysztof Lukaszkowicz, Paulina Kaim, Pietruszka R.

Subject: Engineering, Automotive Engineering Keywords: Keywords: Renewable energy; Nanotechnology; Building-integrated photovoltaics (BIV); Thin films; Dye-sensitized solar cells

Online: 20 May 2021 (09:50:22 CEST)

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Working Paper ARTICLE

Enhancing Third Order Nonlinear Optics in Integrated Ring Resonators with 2D Material Films

Jiayang Wu, Yunyi Yang, Yang Qu, Linnan Jia, Yuning Zhang, Xingyuan Xu, Sai T. Chu, Brent E. Little, Roberto Morandotti, Baohua Jia, David J. Moss

Subject: Physical Sciences, Optics And Photonics Keywords: 2D materials; micro-ring resonator; graphene oxide; Kerr nonlinearity; four-wave mixing; integrated optics

Online: 6 March 2020 (05:33:51 CET)

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Preprint ARTICLE | doi:10.20944/preprints202003.0018.v1

Robust Visual-Inertial Integrated Navigation System Aided by Online Sensor Model Adaption for Autonomous Ground Vehicles in Urban Areas

Xiwei Bai, Weisong Wen, Li-Ta Hsu

Subject: Engineering, Electrical And Electronic Engineering Keywords: visual-inertial integrated navigation system (VINS); visual odometry; autonomous driving; adaptive tuning; urban canyons

Online: 2 March 2020 (00:38:17 CET)

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Working Paper REVIEW

Multi-Resource Watershed Research in the Southwestern USA and the Four Forests Restoration Initiative: A Review

Gerald J. Gottfried, Daniel G. Neary

Subject: Environmental And Earth Sciences, Environmental Science Keywords: watershed; forest restoration; integrated resource management; Southwest USA; Beaver Creek; Thomas Creek; Castle Creek

Online: 11 September 2019 (05:11:42 CEST)

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Working Paper ARTICLE

Novel S-Bend Resonator Based on a Multi-Mode Waveguide with Mode Discrimination for a Refractive Index Sensor

Do-Hyun Kim, Su-Jin Jeon, Jae-Sang Lee, Seok-Ho Hong, Young-Wan Choi

Subject: Physical Sciences, Optics And Photonics Keywords: mode discrimination; multi-mode waveguide; S-bend resonator; refractive index sensor; integrated optical sensor

Online: 18 July 2019 (09:19:20 CEST)

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