REVIEW
|
doi:10.20944/preprints202109.0287.v1
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
drug screening; monodrug or combinatorial drug screening; anti-cancer
Online: 16 September 2021 (13:46:49 CEST)
ARTICLE
|
doi:10.20944/preprints201806.0192.v1
Subject:
Biology And Life Sciences,
Biology And Biotechnology
Keywords:
β4-galactosyltransferase 4; transcriptional mechanism; sensor cells; colon cancer; drug screening
Online: 12 June 2018 (12:51:07 CEST)
REVIEW
|
doi:10.20944/preprints202104.0574.v1
Subject:
Chemistry And Materials Science,
Analytical Chemistry
Keywords:
smart materials; drug delivery systems; flame retardant; industrial coatings; filtration membranes; antifouling coatings.
Online: 21 April 2021 (11:47:42 CEST)
ARTICLE
|
doi:10.20944/preprints202010.0196.v2
Subject:
Medicine And Pharmacology,
Immunology And Allergy
Keywords:
drug discovery; artificial intelligence; protein discovery; binding prediction; synthetic molecule generation; synthetic drug
Online: 20 November 2020 (11:30:03 CET)
REVIEW
|
doi:10.20944/preprints202211.0032.v1
Subject:
Medicine And Pharmacology,
Neuroscience And Neurology
Keywords:
Alzheimer’s disease; Quantum Dot Nanoparticles; PINK1; Theranostic; mitochondria; drug delivery
Online: 1 November 2022 (14:29:26 CET)
ARTICLE
|
doi:10.20944/preprints201905.0370.v1
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
Targeted drug delivery, VX2 tumor, breast cancer, cryoablation, cryo-assisted injection, cryo-assisted resection, blue dye, epirubicin.
Online: 30 May 2019 (13:44:41 CEST)
ARTICLE
|
doi:10.20944/preprints202104.0311.v1
Subject:
Chemistry And Materials Science,
Biomaterials
Keywords:
Chitosan; Silver nanoparticles; Graphene oxide; Nanocomposites; Antibacterial property; Drug delivery
Online: 12 April 2021 (13:59:44 CEST)
ARTICLE
|
doi:10.20944/preprints202204.0224.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
COVID-19; SARS-CoV-2; drug discovery; multitargeting; computational drug repurposing
Online: 26 April 2022 (03:39:06 CEST)
ARTICLE
|
doi:10.20944/preprints201901.0250.v1
Subject:
Medicine And Pharmacology,
Pharmacology And Toxicology
Keywords:
drug delivery system, muscle atrophy, nanoparticle, prostaglandin E1, sciatic nerve injury
Online: 24 January 2019 (08:51:02 CET)
REVIEW
|
doi:10.20944/preprints202109.0496.v1
Subject:
Chemistry And Materials Science,
Polymers And Plastics
Keywords:
Nanomedicine; molecularly imprinted polymer; drug delivery; targeting; hybrid material
Online: 29 September 2021 (14:16:32 CEST)
COMMUNICATION
|
doi:10.20944/preprints202011.0441.v1
Subject:
Biology And Life Sciences,
Anatomy And Physiology
Keywords:
Sars-Cov-2; Proteomic,; Ghost proteome,; Alternative proteins,; AltOrf.; interactomic; drug repurposing
Online: 16 November 2020 (17:50:19 CET)
REVIEW
|
doi:10.20944/preprints202211.0070.v1
Subject:
Biology And Life Sciences,
Food Science And Technology
Keywords:
Nutraceuticals; Personalized Medicine; Precision Medicine; Probiotics; Vitamins; Covid; Dietary Supplements; Adverse Drug Effects
Online: 3 November 2022 (06:27:25 CET)
ARTICLE
|
doi:10.20944/preprints201909.0063.v1
Subject:
Chemistry And Materials Science,
Medicinal Chemistry
Keywords:
FABP4; A-FABP; aP2; antidiabetes; antiobesity; antiatherosclerosis; anticancer; computational tools; computer-aided drug discovery
Online: 5 September 2019 (15:39:58 CEST)
REVIEW
|
doi:10.20944/preprints202207.0031.v1
Subject:
Biology And Life Sciences,
Biophysics
Keywords:
Cell-state transitions; Phenotypic plasticity; Cancer Stem Cells; Intratumoral heterogeneity; Lamarckian Induction; Drug resistance
Online: 4 July 2022 (04:56:00 CEST)
ARTICLE
|
doi:10.20944/preprints201904.0075.v1
Subject:
Chemistry And Materials Science,
Applied Chemistry
Keywords:
amphiphilc copolymer; hydrolyzable polyurea; micelle; controlled drug delivery; cancer chemotherapy
Online: 8 April 2019 (08:35:46 CEST)
ARTICLE
|
doi:10.20944/preprints202108.0031.v1
Subject:
Medicine And Pharmacology,
Immunology And Allergy
Keywords:
antibiotics; antimicrobial resistance; antimicrobial stewardship; AWaRe; Pharmacovigilance; Lareb; adverse drug reactions
Online: 2 August 2021 (12:27:02 CEST)
REVIEW
Subject:
Medicine And Pharmacology,
Anesthesiology And Pain Medicine
Keywords:
pharmacology; drug development; sodium channel; potassium channel; TRP channel; HCN channels
Online: 8 August 2019 (12:31:26 CEST)
REVIEW
|
doi:10.20944/preprints202305.0620.v1
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
ALL; immunotherapy; antibody-drug conjugate; CAR-based therapies, targeted therapies
Online: 9 May 2023 (09:03:11 CEST)
ARTICLE
|
doi:10.20944/preprints201812.0018.v2
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
colorectal cancer; differentially expressed genes; biomarkers; protein-protein interaction; reporter biomolecules; candidate drugs; systems biology; drug repositioning
Online: 29 December 2018 (07:05:05 CET)
REVIEW
|
doi:10.20944/preprints202007.0478.v2
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
Bioinformatics; Drug Design; Small Organic Molecule; Target identification; Web-based Server
Online: 25 July 2020 (17:50:30 CEST)
REVIEW
|
doi:10.20944/preprints202002.0099.v1
Subject:
Biology And Life Sciences,
Virology
Keywords:
retroviruses; HIV-1; reverse transcriptase; mutation rate; drug resistance, allostery
Online: 7 February 2020 (11:50:11 CET)
ARTICLE
Subject:
Computer Science And Mathematics,
Mathematical And Computational Biology
Keywords:
c-src-tyrosine kinase; QSAR; molecular descriptors; virtual screening; drug discovery; cancer; molecular docking
Online: 25 October 2019 (11:21:43 CEST)
REVIEW
|
doi:10.20944/preprints202102.0449.v1
Subject:
Chemistry And Materials Science,
Materials Science And Technology
Keywords:
multifunctional; hydrogel nanocomposties; tissue engineering; drug delivery; wound healing; bioprinting; biowearable devices
Online: 22 February 2021 (08:48:20 CET)
ARTICLE
|
doi:10.20944/preprints201810.0231.v1
Subject:
Medicine And Pharmacology,
Pharmacology And Toxicology
Keywords:
drug release; electrospinning; paclitaxel; polycaprolactone; 3D matrix
Online: 11 October 2018 (06:09:26 CEST)
ARTICLE
|
doi:10.20944/preprints202011.0054.v1
Subject:
Medicine And Pharmacology,
Immunology And Allergy
Keywords:
3D printing; semi-solid extrusion 3D printing; additive manufacturing; extemporaneous manufacturing; drug delivery; personalized dosage forms; veterinary medicine; prednisolone
Online: 2 November 2020 (14:59:30 CET)
ARTICLE
|
doi:10.20944/preprints202105.0229.v1
Subject:
Medicine And Pharmacology,
Immunology And Allergy
Keywords:
extracellular vesicles; melanoma; doxorubicin; drug delivery systems.
Online: 11 May 2021 (10:19:50 CEST)
ARTICLE
|
doi:10.20944/preprints202008.0067.v1
Subject:
Medicine And Pharmacology,
Medicine And Pharmacology
Keywords:
adverse drug reaction; healthcare professionals; pharmacovigilance; surveillance form; suspected ADR
Online: 3 August 2020 (08:49:10 CEST)
REVIEW
|
doi:10.20944/preprints202107.0650.v1
Subject:
Medicine And Pharmacology,
Immunology And Allergy
Keywords:
chronic disorders; inflammation; human superorganism; holobiont; microbiome; multimorbidity; microimmunosome; polypharmacy; drug safety; sustainable healthcare
Online: 29 July 2021 (11:37:20 CEST)
REVIEW
|
doi:10.20944/preprints202105.0726.v1
Subject:
Medicine And Pharmacology,
Immunology And Allergy
Keywords:
Artificial Intelligence; Drug Delivery; Cancer; Nanomedicines; Therapeutic
Online: 31 May 2021 (09:59:30 CEST)
ARTICLE
|
doi:10.20944/preprints201811.0608.v1
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
spheroids; concentration gradient generator; drug screening; high-throughput
Online: 28 November 2018 (10:08:05 CET)
REVIEW
|
doi:10.20944/preprints202206.0333.v1
Subject:
Medicine And Pharmacology,
Medicine And Pharmacology
Keywords:
hPSCs derived-organoids; Culture strategy; Disease modeling; Drug screening; Regenerative therapy
Online: 24 June 2022 (08:11:15 CEST)
REVIEW
Subject:
Chemistry And Materials Science,
Analytical Chemistry
Keywords:
hyperoxaluria; oxalate; inhibitor; small molecule drug; glycolate oxidase; lactate dehydrogenase; liver selective distribution
Online: 31 December 2020 (08:59:47 CET)
ARTICLE
|
doi:10.20944/preprints202104.0483.v1
Subject:
Medicine And Pharmacology,
Pharmacy
Keywords:
Network embedding; multiplex-heterogeneous network; multi-layer network; drug repositioning; graph representation learning
Online: 19 April 2021 (13:21:02 CEST)
REVIEW
|
doi:10.20944/preprints202211.0062.v1
Subject:
Chemistry And Materials Science,
Medicinal Chemistry
Keywords:
membrane transporter; SLC; solute carrier; drug design; pharmacokinetics; prodrug; nanoparticle; bile acids
Online: 3 November 2022 (01:09:54 CET)
ARTICLE
|
doi:10.20944/preprints202104.0222.v1
Subject:
Medicine And Pharmacology,
Immunology And Allergy
Keywords:
ocular surface disease; dry eye disease; antioxidant; Xanthohumol; drug delivery; drug formulation; PLGA; nanoparticles
Online: 8 April 2021 (09:09:24 CEST)
ARTICLE
Subject:
Chemistry And Materials Science,
Nanotechnology
Keywords:
Sepiapterin; triacetyl-β-cyclodextrin (TAβCD); hydrophilic drug/cyclodextrin complexes; spray-drying; methoxy-poly(ethylene-glycol)-poly(epsilon-caprolactone) (mPEG-PCL) nanoparticles
Online: 24 May 2019 (11:42:42 CEST)
ARTICLE
|
doi:10.20944/preprints202212.0326.v1
Subject:
Biology And Life Sciences,
Aging
Keywords:
C. elegans; drug; infection; lifespan; liposome; methodology
Online: 19 December 2022 (06:47:56 CET)
REVIEW
|
doi:10.20944/preprints202306.0220.v1
Subject:
Chemistry And Materials Science,
Biomaterials
Keywords:
hydrogel-forming microneedles; transdermal drug delivery; controlled release; permeation pathway; environmental response
Online: 2 June 2023 (15:57:01 CEST)
ARTICLE
|
doi:10.20944/preprints202110.0021.v1
Subject:
Medicine And Pharmacology,
Medicine And Pharmacology
Keywords:
chitosan; dexketoprofen trometamol; drug delivery; gelatin; NSAIDs; personalized medicine; smart polymers
Online: 1 October 2021 (13:53:53 CEST)
ARTICLE
|
doi:10.20944/preprints201809.0587.v1
Subject:
Biology And Life Sciences,
Biology And Biotechnology
Keywords:
machine learning; conotoxins; cone snails; venom; drug discovery
Online: 29 September 2018 (07:39:42 CEST)
ARTICLE
|
doi:10.20944/preprints202208.0305.v1
Subject:
Medicine And Pharmacology,
Immunology And Allergy
Keywords:
drug repurposing; combination therapeutics; PubMed; ChEBI; disease ontology; gene ontology; drug interaction; MeSH terms; COVID-19
Online: 17 August 2022 (05:51:53 CEST)
ARTICLE
|
doi:10.20944/preprints202206.0177.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
Deuterium-depleted water (DDW); deuterium-depleted organic compounds (DDOC); anticancer drug development; D/H ratio; production of metabolic water; ketogenic diet
Online: 13 June 2022 (09:49:32 CEST)
REVIEW
|
doi:10.20944/preprints202109.0432.v1
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
Non-genetic heterogeneity; multistability; drug-tolerant persisters; phenotypic plasticity; biological noise; epithelial-mesenchymal plasticity; PAGE4
Online: 24 September 2021 (12:44:34 CEST)
REVIEW
|
doi:10.20944/preprints202008.0273.v1
Subject:
Medicine And Pharmacology,
Pharmacology And Toxicology
Keywords:
Mycobacterium abscessus, drug treatment, experimental therapy, review,
Online: 12 August 2020 (08:01:41 CEST)
REVIEW
|
doi:10.20944/preprints202210.0148.v1
Subject:
Medicine And Pharmacology,
Pharmacology And Toxicology
Keywords:
drug development; high throughput screening; in vivo/in silico screening; zebrafish
Online: 11 October 2022 (10:33:33 CEST)
REVIEW
|
doi:10.20944/preprints202105.0143.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
Co-infection; Drug resistance; Gut microbiota; Salmonellosis; Schistosoma
Online: 7 May 2021 (12:02:03 CEST)
CONCEPT PAPER
|
doi:10.20944/preprints202001.0040.v1
Subject:
Medicine And Pharmacology,
Pharmacology And Toxicology
Keywords:
cybernetics; complex systems; new drug development; human system
Online: 5 January 2020 (15:38:27 CET)
CONCEPT PAPER
|
doi:10.20944/preprints202008.0531.v1
Subject:
Medicine And Pharmacology,
Cardiac And Cardiovascular Systems
Keywords:
endocarditis; surgery; cardiac surgery; drug abuse; ethics
Online: 24 August 2020 (11:36:38 CEST)
CASE REPORT
|
doi:10.20944/preprints202304.0705.v1
Subject:
Medicine And Pharmacology,
Gastroenterology And Hepatology
Keywords:
Drug-induced liver injury; ocrelizumab; hepatotoxicity
Online: 21 April 2023 (09:41:29 CEST)
ARTICLE
|
doi:10.20944/preprints201809.0076.v1
Subject:
Medicine And Pharmacology,
Pharmacology And Toxicology
Keywords:
pharmacovigilance; drug safety; segmented regression; interrupted time series; variation
Online: 5 September 2018 (01:27:54 CEST)
REVIEW
|
doi:10.20944/preprints202105.0643.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
Nanocarriers; Nanotheranostics; Nuclear Medicine; Nanoparticles; Drug delivery
Online: 26 May 2021 (14:00:58 CEST)
REVIEW
|
doi:10.20944/preprints202108.0112.v1
Subject:
Biology And Life Sciences,
Immunology And Microbiology
Keywords:
Epitranscriptomics, Immune checkpoint blockage (ICB) therapy, anti-PD-1/PD-L1 drug resistance, Personalized medicine, CISH, microRNAs
Online: 4 August 2021 (13:02:22 CEST)
ARTICLE
|
doi:10.20944/preprints201810.0088.v1
Subject:
Chemistry And Materials Science,
Biomaterials
Keywords:
There are many molecules used as drug carrier. TUD-1 is a newly synthesized mesoporous silica (SM) molecule possess two important features; consists of mesoporous so it is very suitable to be drug carrier in addition to that it has the ability to induce apoptosis in cancer cells. However, the effect of TUD-1 appears to act as cell death inducer, regardless of whether it is necrosis or apoptosis. Unfortunately, recent studies indicate that a proportion of cells undergo necrosis rather than apoptosis, which limits the use of TUD-1 as a secure treatment. On the other hand, lithium considered as necrosis inhibitor element. Hence, current study based on the idea of production a new Li/TUD-1 by incorporated mesoporous silica (TUD-1 type) with lithium in order to produce a new compound that has the ability to activate apoptosis by mesoporous silica (TUD-1 type) and at the same time can inhibit the activity of necrosis by lithium. Herein, lithium was incorporated in TUD-1 mesoporous silica by
Online: 4 October 2018 (15:54:02 CEST)
REVIEW
|
doi:10.20944/preprints202210.0347.v1
Subject:
Medicine And Pharmacology,
Pharmacology And Toxicology
Keywords:
monkeypox virus; infection; treatment; antiviral; drug; management; public health emergency; tecovirimat; cidofovir; bibliometric analysis
Online: 24 October 2022 (03:38:12 CEST)
REVIEW
|
doi:10.20944/preprints202308.0887.v1
Subject:
Chemistry And Materials Science,
Medicinal Chemistry
Keywords:
Drug Discovery; Drug Repurposing; SARS-CoV-2; COVID; Molecular Docking; QSAR; Molecular Dynamic; Virtual Screening; Drug Design
Online: 11 August 2023 (09:03:55 CEST)
ARTICLE
|
doi:10.20944/preprints202009.0047.v1
Subject:
Medicine And Pharmacology,
Pharmacy
Keywords:
silk fibroin; nanoparticles; drug loading content; quantification; infrared spectroscopy; FTIR spectroscopy.; nanotechnology; nanomedicine; drug delivery; controlled release
Online: 3 September 2020 (03:56:19 CEST)
REVIEW
|
doi:10.20944/preprints202009.0417.v1
Subject:
Medicine And Pharmacology,
Psychiatry And Mental Health
Keywords:
schizophrenia; stress; drug policy; environment; contaminants; pesticides; fungi; prohibition
Online: 18 September 2020 (04:21:43 CEST)
REVIEW
|
doi:10.20944/preprints202110.0450.v1
Subject:
Medicine And Pharmacology,
Gastroenterology And Hepatology
Keywords:
Fibrosis; Integrin; TGFβ; Therapeutic target; Drug; Inhibitor; Monoclonal antibody; α8β1; α11β1; Hepatic stellate cell
Online: 29 October 2021 (10:16:13 CEST)
BRIEF REPORT
|
doi:10.20944/preprints202009.0655.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
urinary tract infections; multi-drug resistance; biofilm; virulence genes; WGS
Online: 27 September 2020 (02:40:41 CEST)
ARTICLE
|
doi:10.20944/preprints202111.0364.v1
Subject:
Medicine And Pharmacology,
Ophthalmology
Keywords:
Polymeric micelles; cannabidiol (CBD); spray-drying; ocular drug delivery; corneal epithelial cells
Online: 19 November 2021 (14:48:27 CET)
REVIEW
|
doi:10.20944/preprints202212.0112.v1
Subject:
Chemistry And Materials Science,
Nanotechnology
Keywords:
Gastro retentive drug delivery systems; non-effervescent systems; floating drug delivery systems; microballoons; CRDDS
Online: 7 December 2022 (02:26:58 CET)
ARTICLE
|
doi:10.20944/preprints202109.0275.v1
Subject:
Medicine And Pharmacology,
Pharmacy
Keywords:
Cloud infrastructure; Spark; Molecular Dynamics simulations; Drug design.
Online: 16 September 2021 (11:02:38 CEST)
ARTICLE
|
doi:10.20944/preprints201911.0104.v1
Subject:
Chemistry And Materials Science,
Medicinal Chemistry
Keywords:
chemical synthesis; IC50; ED50; CC50; antimalarial resistance; sarcosine-aniline hybrid drug
Online: 10 November 2019 (10:10:15 CET)
REVIEW
|
doi:10.20944/preprints202109.0491.v1
Subject:
Biology And Life Sciences,
Immunology And Microbiology
Keywords:
Tuberculosis; Mycobacterium; Diagnostics; Drug Discovery; Antibiotics; Antimicrobial Re-sistance; Microfluidics; Single-Cell Analysis; Bioengineered Models
Online: 29 September 2021 (11:34:04 CEST)
ARTICLE
|
doi:10.20944/preprints201907.0043.v1
Subject:
Computer Science And Mathematics,
Applied Mathematics
Keywords:
Network biology; LINE; lncRNA; protein; miRNA; Drug; disease
Online: 2 July 2019 (11:42:26 CEST)
COMMUNICATION
|
doi:10.20944/preprints202007.0709.v1
Subject:
Biology And Life Sciences,
Cell And Developmental Biology
Keywords:
intrinsic multi-drug resistance; acquired multi-drug resistance; circulating tumor cells; single cells; cell clusters; cell monolayer; multi-cellular spheroids; cytometry of reaction rate constant; ovarian cancer
Online: 30 July 2020 (09:01:50 CEST)
ARTICLE
|
doi:10.20944/preprints202106.0169.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
melanoma initiating cells; CD133; drug resistance; apoptosis; caspase activation; CRISPR-Cas9 knockout; AKT; BAD; BCL-2 family
Online: 7 June 2021 (12:11:10 CEST)
REVIEW
|
doi:10.20944/preprints202104.0733.v1
Subject:
Medicine And Pharmacology,
Immunology And Allergy
Keywords:
Topoisomerase I; irinotecan; camptothecin; ubiquitination; proteasomal degradation; drug resistance
Online: 28 April 2021 (08:44:34 CEST)
REVIEW
|
doi:10.20944/preprints202112.0380.v2
Subject:
Medicine And Pharmacology,
Medicine And Pharmacology
Keywords:
sex differences; drug repurposing; sex-bias; sex-aware; review; therapeutics; pharmaceuticals; computational drug repurposing
Online: 8 March 2022 (10:34:42 CET)
REVIEW
|
doi:10.20944/preprints202210.0450.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
Tumor microenvironment; stromal cells; immune cells; ECM; cancer hallmarks; hypoxia; exosomes; drug resistance; targeted therapy
Online: 28 October 2022 (09:57:34 CEST)
ARTICLE
|
doi:10.20944/preprints202202.0194.v1
Subject:
Medicine And Pharmacology,
Pulmonary And Respiratory Medicine
Keywords:
antifungal resistance; isavuconazole; cystic fibrosis; pulmonary disease; Aspergillus fumigatus; pulmonary aspergillosis; respiratory disease; antifungal stewardship; therapeutic drug monitoring; minimum inhibitory concentration (MIC)
Online: 16 February 2022 (05:12:39 CET)
ARTICLE
|
doi:10.20944/preprints202206.0417.v1
Subject:
Chemistry And Materials Science,
Nanotechnology
Keywords:
lecithin; ginger oil; essential oil; nano-lipid; drug delivery system
Online: 30 June 2022 (08:00:31 CEST)
ARTICLE
Subject:
Medicine And Pharmacology,
Immunology And Allergy
Keywords:
Drug Safety Surveillance; Adverse Drug Reaction; Ophthalmic; Ciprofloxacin; Dexamethasone
Online: 5 January 2021 (11:51:06 CET)
REVIEW
|
doi:10.20944/preprints202303.0464.v1
Subject:
Medicine And Pharmacology,
Pharmacology And Toxicology
Keywords:
Therapeutic proteins; Recombinant proteins; Repurposing; Reinventing, Drug-antibody combinations, AI/ML, Efficacy improvement, Immunogenicity; Artificial Intelligence; mRNA; High throughput analysis
Online: 27 March 2023 (14:02:03 CEST)
ARTICLE
|
doi:10.20944/preprints202208.0013.v1
Subject:
Public Health And Healthcare,
Public, Environmental And Occupational Health
Keywords:
parental presence; alcohol and drug consumption; deviant behaviours; adolescents
Online: 1 August 2022 (08:52:00 CEST)
ARTICLE
|
doi:10.20944/preprints201811.0478.v1
Subject:
Biology And Life Sciences,
Neuroscience And Neurology
Keywords:
Japanese encephalitis virus; drug repurposing; systems biology; antiviral agents
Online: 20 November 2018 (04:54:48 CET)
REVIEW
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
apoptosis; antitumor; antimetastasis; anti-angiogenesis; NK-1 receptor; substance P; drug repositioning; Emend
Online: 31 August 2020 (10:11:13 CEST)
REVIEW
|
doi:10.20944/preprints202203.0237.v1
Subject:
Medicine And Pharmacology,
Medicine And Pharmacology
Keywords:
academy; drug development; industrial pharmacy; pharmaceutical technology; research method-ology
Online: 17 March 2022 (01:56:47 CET)
ARTICLE
|
doi:10.20944/preprints202011.0474.v1
Subject:
Biology And Life Sciences,
Endocrinology And Metabolism
Keywords:
Breast cancer, genome-scale metabolic models, constraint-based analysis, divergence analysis, gene expression, metabolism, drug targets, personalized metabolic networks.
Online: 18 November 2020 (12:29:02 CET)
REVIEW
|
doi:10.20944/preprints202004.0012.v1
Subject:
Chemistry And Materials Science,
Theoretical Chemistry
Keywords:
chemoinformatics; chemical space; database; LANaPD; molecular diversity; drug discovery; natural sources
Online: 2 April 2020 (04:47:13 CEST)
ARTICLE
|
doi:10.20944/preprints202002.0003.v1
Subject:
Medicine And Pharmacology,
Pharmacology And Toxicology
Keywords:
drug repositioning/repurposing; dopamine transporter (DAT); benztropine; tumoroids; signal transducer and activator of transcription (STAT); circulating tumor cells (CTC); three-dimensional (3D) culture
Online: 3 February 2020 (03:16:54 CET)
ARTICLE
Subject:
Public Health And Healthcare,
Nursing
Keywords:
barcode medication administration (BCMA); nurses’ workflow; inpatient setting; drug round
Online: 28 July 2020 (05:07:23 CEST)
REVIEW
|
doi:10.20944/preprints202111.0317.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
Non-Hodgkin lymphoma; Epigenetics; DNA methylation; HAT; HDAC; EZH2; bromodomain inhibitors; Drug combination; clinical testing
Online: 17 November 2021 (23:45:00 CET)
ARTICLE
|
doi:10.20944/preprints202302.0250.v1
Subject:
Medicine And Pharmacology,
Other
Keywords:
AI drug discovery; mTOR; rapalog; C. elegans; cancer; longevity
Online: 15 February 2023 (02:42:57 CET)
REVIEW
|
doi:10.20944/preprints202201.0117.v1
Subject:
Biology And Life Sciences,
Cell And Developmental Biology
Keywords:
G protein-coupled receptor; mouse models; skin cancer; UVR; drug; network
Online: 10 January 2022 (13:41:08 CET)
ARTICLE
|
doi:10.20944/preprints202107.0270.v1
Subject:
Chemistry And Materials Science,
Analytical Chemistry
Keywords:
drug design; falcipain; malaria; peptidomimetics; Plasmodium falciparum; virtual screening; pharmacophore.
Online: 12 July 2021 (14:48:13 CEST)
ARTICLE
|
doi:10.20944/preprints201905.0109.v2
Subject:
Medicine And Pharmacology,
Pediatrics, Perinatology And Child Health
Keywords:
child; diarrhea; water sanitation and hygiene; rehydration solution; zinc; case management; antibacterial agents; drug utilization; community participation; India
Online: 14 May 2019 (11:46:53 CEST)
ARTICLE
|
doi:10.20944/preprints202209.0288.v1
Subject:
Biology And Life Sciences,
Virology
Keywords:
COVID-19; Therapeutics; Drug Repurposing; 3D Tissue Models
Online: 20 September 2022 (03:24:22 CEST)
REVIEW
|
doi:10.20944/preprints202203.0032.v1
Subject:
Chemistry And Materials Science,
Medicinal Chemistry
Keywords:
artificial intelligence; machine learning; drug design; covid-19; structure-based drug design; ligand-based drug design
Online: 2 March 2022 (03:00:37 CET)
ARTICLE
|
doi:10.20944/preprints202002.0009.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
target identification; drug affinity responsive target stability (DARTS); mass spectrometry imaging (MSI); voacangine; curcumin; natural products
Online: 3 February 2020 (04:36:54 CET)
REVIEW
|
doi:10.20944/preprints201812.0273.v3
Subject:
Biology And Life Sciences,
Biophysics
Keywords:
mutations; disease-causing mutations; polymorphism; folding free energy change; binding free energy change; drug discovery; in silico screening
Online: 28 January 2019 (11:39:23 CET)
REVIEW
|
doi:10.20944/preprints202306.0232.v1
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
Antibody-drug conjugate; cancer; clinical trials
Online: 5 June 2023 (04:13:02 CEST)
REVIEW
|
doi:10.20944/preprints202212.0048.v1
Subject:
Chemistry And Materials Science,
Biomaterials
Keywords:
poly(hexamethylene biguanide); polyhexamethylene biguanide; polyhexanide; PHMB; membrane; controlled drug release; wound dressing; antimicrobial; cytotoxicity; wound healing
Online: 2 December 2022 (10:31:38 CET)
REVIEW
|
doi:10.20944/preprints201907.0286.v1
Subject:
Biology And Life Sciences,
Virology
Keywords:
HIV-1 Gag; Gag inhibitors; Protease; Protease inhibitors; drug resistance mutations; drug design
Online: 25 July 2019 (10:05:03 CEST)
REVIEW
|
doi:10.20944/preprints202207.0379.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
Montelukast; Leukotrienes; Adverse drug reactions; Repurposing
Online: 26 July 2022 (03:27:37 CEST)
ARTICLE
|
doi:10.20944/preprints202207.0004.v1
Subject:
Medicine And Pharmacology,
Pharmacology And Toxicology
Keywords:
SARS-CoV-2; COVID-19; drug repurposing; artificial intelligence; target-target similarity network; drug-target interaction network
Online: 1 July 2022 (05:33:16 CEST)
ARTICLE
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
adlay; adlay bran oil; cytochrome P450; food-drug interactions; rats
Online: 10 September 2019 (03:16:30 CEST)
ARTICLE
|
doi:10.20944/preprints201908.0177.v1
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
chronic myeloid leukemia; tyrosine kinase inhibitor; adverse drug event; quality of life; second-generation tyrosine kinase inhibitor; nilotinib
Online: 16 August 2019 (08:09:07 CEST)
REVIEW
|
doi:10.20944/preprints202008.0313.v2
Subject:
Biology And Life Sciences,
Animal Science, Veterinary Science And Zoology
Keywords:
drug resistance; natural diversity; C. elegans; anthelmintics
Online: 25 November 2020 (14:47:29 CET)
ARTICLE
|
doi:10.20944/preprints202106.0717.v1
Subject:
Medicine And Pharmacology,
Immunology And Allergy
Keywords:
hyperthyroidism; thyrotoxicosis; Graves’ disease; pregnancy; antithyroid drug; drug withdrawal; postpartum recurrence; birth defects
Online: 30 June 2021 (00:09:17 CEST)