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Preprint ARTICLE | doi:10.20944/preprints201906.0310.v1

Insights into the Diversity of Secondary Metabolites of Planktothrix Using a Biphasic Approach Combining Global Genomics and Metabolomics

Sanrda Kim Tiam, Muriel Gugger, Justine Demay, Severine Le Manach, Charlotte Duval, Cecile Bernard, Benjamin Marie

Subject: Biology And Life Sciences, Immunology And Microbiology Keywords: cyanobacteria; secondary metabolite; genome mining; molecular networking

Online: 30 June 2019 (10:42:22 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202103.0271.v1

Clinical Characteristics, Activity Levels and Mental Health Problems in Children with Long COVID: A Survey of 510 Children

Danilo Buonsenso, Ferran Espuny Pujol, Daniel Munblit, Sammie Mcfarland, Frances Simpson

Subject: Medicine And Pharmacology, Immunology And Allergy Keywords: long covid; children; SARS-CoV-2

Online: 9 March 2021 (12:37:24 CET)

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Preprint REVIEW | doi:10.20944/preprints201607.0012.v1

Analysis of Access Control Methods in Cloud Computing

Madhura Mulimani, Rashmi Rachh

Subject: Computer Science And Mathematics, Information Systems Keywords: role-based access control; attribute-based access control; attribute-based encryption

Online: 8 July 2016 (10:12:21 CEST)

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Preprint REVIEW | doi:10.20944/preprints201811.0162.v1

A Review of Geological Applications of High-Spatial-Resolution Remote Sensing Data

Chunming Wu, Xiao Li, Weitao Chen, Xianju Li

Subject: Environmental And Earth Sciences, Geophysics And Geology Keywords: High-spatial-resolution images; Geology; Deep learning; Remote sensing

Online: 7 November 2018 (13:17:40 CET)

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Preprint ARTICLE | doi:10.20944/preprints201802.0117.v1

Assessment of the History and Cultural Inclusion of Public Art in Pakistan

Syed Asifullah Shah, Ashfaq Ahmad Shah, Xianfeng Li

Subject: Arts And Humanities, Art Keywords: Public Art; Cultural identity; Islamic society; Art history; Pakistan.

Online: 18 February 2018 (13:16:07 CET)

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Preprint ARTICLE | doi:10.20944/preprints202108.0460.v1

Optimization of N, P, K for Soilless Production of Cannabis sativa in the Flowering Stage Using Response Surface Analysis

Lewys Bevan, Max Jones, Youbin Zheng

Subject: Biology And Life Sciences, Horticulture Keywords: Cannabis; cannabinoids; nutrients; nitrogen (N); phosphorus (P); potassium (K); yield; response surface methodology

Online: 24 August 2021 (08:40:44 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202010.0520.v1

Planning and Design Techniques of Tourism Complexes in the Process of the City's Master Planning

Abdol Aziz Shahraki

Subject: Engineering, Automotive Engineering Keywords: Urban planning; land use policy; tourism planning; urban management; tourism complex; master planning

Online: 26 October 2020 (12:00:42 CET)

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Preprint ARTICLE | doi:10.20944/preprints201809.0508.v1

Moringa Oleifera L. Extracts as Bioactive Ingredients That Increasing Safety of Body Wash Cosmetics

Zofia Nizioł-Łukaszewska, Dominika Furman-Toczek, Tomasz Bujak, Tomasz Wasilewski

Subject: Biology And Life Sciences, Biochemistry And Molecular Biology Keywords: Moringa oleifera L., antioxidant activity, cell culture, irritant potential

Online: 26 September 2018 (13:16:14 CEST)

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Preprint REVIEW | doi:10.20944/preprints202007.0744.v1

DNA Processing in The Context of Non-Coding Transcription

Uthra Gowthaman, Desiré García-Pichardo, Yu Jin, Isabel Schwarz, Sebastian Marquardt

Subject: Biology And Life Sciences, Biochemistry And Molecular Biology Keywords: long non-coding RNA (lncRNA); RNA polymerase II (RNAPII) transcription; gene regulation; tandem transcriptional interference (tTI); antisense transcription; DNA processing

Online: 31 July 2020 (10:47:08 CEST)

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Working Paper REVIEW

Immunogenicity of Clinically Relevant SARS-CoV-2 Vaccines in Non-human Primates and Humans

P.J. Klasse, D. F. Nixon, J. P. Moore

Subject: Medicine And Pharmacology, Immunology And Allergy Keywords: SARS-CoV-2; S-protein; RBD; COVID-19; neutralizing antibodies; serology; T-cells; vaccines; animal models; Operation Warp Speed

Online: 7 September 2020 (12:29:06 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202002.0220.v1

Pulmonary Pathology of Early Phase SARS-COV-2 Pneumonia

Sufang Tian, Weidong Hu, Li Niu, Huan Liu, Haibo Xu, Shu-Yuan Xiao

Subject: Medicine And Pharmacology, Pathology And Pathobiology Keywords: coronavirus; COVID-19 pneumonia; pathology; SARS-CoV-2

Online: 16 February 2020 (14:41:28 CET)

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Preprint ARTICLE | doi:10.20944/preprints201805.0258.v2

Revisiting the Derivation of Heisenberg's Uncertainty Principle: The Collapse of Uncertainty at the Planck Scale

Espen Haug

Subject: Physical Sciences, Thermodynamics Keywords: Heisenberg's uncertainty principle; certainty; wave function; Planck scale; Planck mass; Planck particle; Bell's Inequality; superposition; entropy; Compton clock

Online: 5 September 2018 (09:34:51 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202003.0161.v1

The Small Intestine, an Underestimated Site of SARS-CoV-2 Infection: From Red Queen Effect to Probiotics

Zhijie Feng, Yan Wang, Wei Qi

Subject: Biology And Life Sciences, Immunology And Microbiology Keywords: coronaviruses receptors; angiotensin-converting enzyme 2 (ACE2); COVID-19; SARS-Cov-2; the Red Queen hypothesis; segmented filamentous bacteria

Online: 10 March 2020 (08:45:34 CET)

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Preprint ARTICLE | doi:10.20944/preprints201912.0351.v1

Simulation of Turbulent Flow around a Generic High-Speed Train Using Hybrid Models of RANS Numerical Method with Machine Learning

Alireza Hajipour, Arash Mirabdolah Lavasani, Mohammad Eftekhari Yazdi, Amir Mosavi, Shahaboddin Shamshirband, Kwok-Wing Chau

Subject: Computer Science And Mathematics, Artificial Intelligence And Machine Learning Keywords: machine learning; aerodynamics; high-speed train; hybrid machine learning; Prediction Turbulence model; deep learning

Online: 26 December 2019 (05:23:14 CET)

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Preprint ARTICLE | doi:10.20944/preprints201608.0048.v1

UAV Low Altitude Photogrammetry for Power Line Inspection

Yong Zhang, Xiuxiao Yuan, Yi Fang, Shiyu Chen

Subject: Environmental And Earth Sciences, Remote Sensing Keywords: UAV remote sensing; power line inspection; dense matching; virtual photography; automatic detection of obstacles in power line corridor

Online: 5 August 2016 (08:07:23 CEST)

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Preprint ARTICLE | doi:10.20944/preprints201904.0221.v1

Economic and Environmental Multi-objective Optimization of a Wind-Solar-Fuel Cell Hybrid Energy System in the Colombian Caribbean Region

Guillermo Valencia, Aldair Benavides, Yulineth Cardenas

Subject: Engineering, Energy And Fuel Technology Keywords: fuel cell; wind energy; solar energy; hybrid energy system; Colombian caribbean region; multi-objective optimization

Online: 19 April 2019 (11:40:02 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202002.0181.v1

Evaluation of Electrical Efficiency of Photovoltaic Thermal Solar Collector

Mohammad Hossein Ahmadi, Alireza Baghban, Milad Sadeghzadeh, Mohammad Zamen, Amir Mosavi, Shahaboddin Shamshirband, Ravinder Kumar, Mohammad Mohammadi-Khanaposhtani

Subject: Computer Science And Mathematics, Artificial Intelligence And Machine Learning Keywords: renewable energy; neural networks (NNs); adaptive neuro-fuzzy inference system (ANFIS); least square support vector machine (LSSVM); photovoltaic-thermal (PV/T); hybrid machine learning model

Online: 14 February 2020 (02:53:47 CET)

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Preprint CONCEPT PAPER | doi:10.20944/preprints201911.0045.v1

Contribution of Micro Finance on Poverty Alleviation in Bangladesh

Arman Hossen, Md. Rubel Miah, Roksana Aftab Ruhi

Subject: Business, Economics And Management, Finance Keywords: microfinance; poverty; MFI’s; NGO

Online: 5 November 2019 (05:28:48 CET)

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Preprint ARTICLE | doi:10.20944/preprints201701.0070.v1

Performance Evaluation of a Permanent Magnet-Assisted Synchronous Reluctance Machine with Hybrid Magnets of Ferrite Magnets and Rare-earth PMs

Xiping Liu, Ya Li, Zhangqi Liu

Subject: Engineering, Electrical And Electronic Engineering Keywords: permanent magnet-assisted synchronous reluctance machine; power factor; torque ripple; efficiency; demagnetization; finite element analysis

Online: 13 January 2017 (11:04:02 CET)

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Preprint ARTICLE | doi:10.20944/preprints201607.0001.v1

Forecasting Wholesale Electricity Prices With Artificial Intelligence Models: The Italian Case

Murad Harasheh

Subject: Business, Economics And Management, Finance Keywords: PUN, artificial intelligence models, regression tree, bootstrap aggregation, forecasting error

Online: 2 July 2016 (03:48:36 CEST)

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Preprint REVIEW | doi:10.20944/preprints202103.0216.v1

Machine Learning: Algorithms, Real-World Applications and Research Directions

Iqbal H. Sarker

Subject: Computer Science And Mathematics, Information Systems Keywords: machine learning; deep learning; artificial intelligence; data science; data-driven decision making; predictive analytics; intelligent applications;

Online: 8 March 2021 (12:55:59 CET)

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Preprint ARTICLE | doi:10.20944/preprints201811.0156.v1

Real Time Human Detection and Localization Using Consumer Grade Camera and Commercial UAV

Nemi Bhattarai, Tai Nakamura, Chitrini Mozumder

Subject: Computer Science And Mathematics, Information Systems Keywords: Unmanned Aerial Vehicle (UAV), Haar-like features, real time, Geographic Information Systems (GIS), human detection, geolocation error, OpenCV

Online: 7 November 2018 (09:41:39 CET)

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Preprint ARTICLE | doi:10.20944/preprints202006.0149.v1

Aerodynamic Study of an Ahmed Body with the Help of CFD Simulation

Indrashis Saha, Tathagatha Mukherjee, Ankit Saha, Richa Pandey

Subject: Engineering, Mechanical Engineering Keywords: Ahmed Body; vehicle aerodynamics; drag force measurement; Simulation/Numerical investigation

Online: 12 June 2020 (12:20:55 CEST)

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Preprint REVIEW | doi:10.20944/preprints201702.0083.v2

Plant Responses to Salt Stress: Adaptive Mechanisms

Jose Ramón Acosta-Motos, Maria Fernanda Ortuño, Agustina Bernal-Vicente, Pedro Diaz-Vivancos, Maria Jesus Sanchez-Blanco, Jose Antonio Hernandez

Subject: Biology And Life Sciences, Plant Sciences Keywords: Adaptive mechanisms; antioxidative metabolism; chloroplast; osmotic regulation; oxidative stress; photosynthesis; salinity; water relations

Online: 24 February 2017 (10:21:50 CET)

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Preprint ARTICLE | doi:10.20944/preprints201704.0134.v1

Quantum Fisher Information: Theory and Applications

Volkan Erol

Subject: Computer Science And Mathematics, Computer Science Keywords: quantum metrology; quantum fisher ınformation; decoherence; optimization

Online: 21 April 2017 (06:17:36 CEST)

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Preprint REVIEW | doi:10.20944/preprints202002.0007.v1

CRISPR-Cas Systems for Diagnosing Infectious Diseases

Anastasiya Kostyusheva, Sergey Brezgin, Yurii Babin, Irina Vasil'eva, Dmitry Kostyushev, Vladimir Chulanov

Subject: Biology And Life Sciences, Virology Keywords: molecular diagnostics; molecular epidemiology; HIV; HBV; HCV; HPV; Zika virus; Dengue virus; tuberculosis; SARS; MERS; nCov-2019

Online: 3 February 2020 (03:47:27 CET)

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Infectious diseases are a global health problem affecting billions of people. Developing rapid and sensitive diagnostic tools is key for successful patient management and curbing disease spread. Currently available diagnostics are very specific and sensitive but time-consuming and require expensive laboratory settings and well-trained personnel; thus, they are not available in resource-limited areas, for the purposes of large-scale screenings and in case of outbreaks and epidemics. Developing new, rapid, and affordable point-of-care diagnostic assays is urgently needed. This review focuses on CRISPR-based technologies and their perspectives to become platforms for point-of-care nucleic acid detection methods and as deployable diagnostic platforms that could help to identify and curb outbreaks and emerging epidemics. We describe the mechanisms and function of different classes and types of CRISPR-Cas systems, including pros and cons for developing molecular diagnostic tests and applications of each type to detect a wide range of infectious agents. Many Cas proteins (Cas9, Cas12, Cas13, Cas14) have been leveraged to create highly accurate and sensitive diagnostic tools combined with technologies of signal amplification and fluorescent, potentiometric, colorimetric, or lateral flow assay detection. In particular, the most advanced platforms -- SHERLOCK/v2, DETECTR, or CRISPR-Chip -- enable detection of attomolar amounts of pathogenic nucleic acids with specificity comparable to that of PCR but with minimal technical settings. Further developing CRISPR-based diagnostic tools promises to dramatically transform molecular diagnostics, making them easily affordable and accessible virtually anywhere in the world. The burden of socially significant diseases, frequent outbreaks, recent epidemics (MERS, SARS and the ongoing coronoviral nCov-2019 infection) urgently need the developing of express-diagnostic tools. Recently devised CRISPR-technologies represent the unprecedented opportunity to reshape epidemiological surveillance and molecular diagnostics.

Preprint ARTICLE | doi:10.20944/preprints201808.0145.v1

A New All-Solid-State Lithium-Ion Battery Working without a Separator in an Electrolyte

Seonggyu Cho, Shinho Kim, Wonho Kim, Seok Kim, Sungsook Ahn

Subject: Chemistry And Materials Science, Biomaterials Keywords: secondary lithium ion battery; all-solid-state battery; solid polymer electrolyte; succinonitrile (SN); lithium(trifluoromethanesulfonyl)imide (LiTFSI)

Online: 7 August 2018 (13:18:20 CEST)

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Preprint ARTICLE | doi:10.20944/preprints201901.0318.v1

Impact of Intellectual Capital on Firm Value: The Moderating Role of Managerial Ownership

Aftab Ahmed, Muhammad Kashif Khurshid, Muhammad Usman Yousaf

Subject: Business, Economics And Management, Finance Keywords: intellectual capital; firm value; managerial ownership; Tobin's Q; VAIC

Online: 31 January 2019 (06:44:01 CET)

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Working Paper ARTICLE

Deep-Learning Based Real-Time Multiple-Object Detection and Tracking from Aerial Imagery via Flying Robot with GPU-based Embedded Devices

Sabir Hossain, Deok-Jin Lee

Subject: Engineering, Control And Systems Engineering Keywords: Multi-Target Detection and Tracking; Multi-copter Drone; Aerial Imagery, Image Sensor, Deep Learning, GPU-based Embedded Module, Neural Computing Stick; Image Processing

Online: 18 July 2019 (10:09:05 CEST)

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Preprint ARTICLE | doi:10.20944/preprints201709.0145.v1

Independent Assessment and Benchmarking of no/low cost Finite Element Analysis Software for Linear Static Structural Analysis

Saien Rugdeo, Clinton Bemont, Jean-François Pitot de la Beaujardiere

Subject: Engineering, Mechanical Engineering Keywords: Open source; FEA; finite element analysis; linear static structural; Code Aster; Salome Meca; Mecway; SimScale; Z88, CAE

Online: 28 September 2017 (14:58:31 CEST)

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Preprint TECHNICAL NOTE | doi:10.20944/preprints201901.0106.v1

Creating a new model in NS3 Network Simulator

Lesly Maygua-Marcillo, Luis Urquiza-Aguiar, Martha Paredes-Paredes

Subject: Engineering, Electrical And Electronic Engineering Keywords: error model; new model; NS-3; VANET; 802.11p

Online: 11 January 2019 (07:59:28 CET)

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Preprint ARTICLE | doi:10.20944/preprints201903.0104.v1

Cyber Risk in IoT Systems

Petar Radanliev, David Charles De Roure, Carsten Maple, Jason R.C. Nurse, Razvan Nicolescu, Uchenna Ani

Subject: Engineering, Control And Systems Engineering Keywords: cyber risk; Internet of Things; cyber risk impact assessment; cyber risk estimation; cyber risk insurance

Online: 8 March 2019 (08:50:49 CET)

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Preprint ARTICLE | doi:10.20944/preprints201701.0003.v1

Microbiological Quality of a Locally Brewed Alcoholic Beverage (Pito) Sold in a Community within the Greater Accra Region, Ghana

Andrew A Minamor, Alberta Mensah Larteley, Emmanuel Nii Laryea, Emmanuel Afutu, Patience B Tetteh-Quarcoo

Subject: Biology And Life Sciences, Food Science And Technology Keywords: pito; beverage; bacteria; coliform; Lower Prampram; Ghana

Online: 2 January 2017 (10:55:07 CET)

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Preprint ARTICLE | doi:10.20944/preprints201803.0183.v1

Financial Inclusion in Bangladesh: Policy Recommendations for Modified Unit Banking System

Hossain Mohammed Omar Khayum, Noshin Tasneem

Subject: Business, Economics And Management, Economics Keywords: financial inclusion; unit banking; banking in Bangladesh; banking policy

Online: 21 March 2018 (03:18:47 CET)

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Preprint ARTICLE | doi:10.20944/preprints202005.0264.v1

Rapid Quantification and Neutralization Assays for Novel Coronavirus SARS-CoV-2 Using Avicel RC-591 Semi-Solid Overlay

Anna N. Honko, Nadia Storm, David J. Bean, Jhonatan Henao Vasquez, Sierra N. Downs, Anthony Griffiths

Subject: Biology And Life Sciences, Virology Keywords: plaque assay; neutralization; SARS; SARS-CoV-2; coronavirus; Avicel; methylcellulose; COVID

Online: 16 May 2020 (15:51:52 CEST)

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Preprint REVIEW | doi:10.20944/preprints202005.0050.v1

The Public Mental Health While in a Community Quarantine Due to COVID-19 Pandemic: A Scoping Review of Literature Using Google Scholar

Ryan Labana

Subject: Social Sciences, Psychology Keywords: COVID-19 Pandemic; Review Literature; Psychosocial Support System; Public Health Administration

Online: 5 May 2020 (02:23:47 CEST)

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Preprint REVIEW | doi:10.20944/preprints202012.0037.v1

Recommendations for Healthy Daytime, Evening, and Night-Time Indoor Light Exposure

Timothy Brown, George Brainard, Christian Cajochen, Charles Czeisler, John Hanifin, Steven Lockley, Robert Lucas, Mirjam Munch, John O'Hagan, Stuart Peirson, Luke Price, Till Roenneberg, Luc Schlangen, Debra Skene, Manuel Spitschan, Celine Vetter, Phyllis Zee, Kenneth Wright Jr.

Subject: Biology And Life Sciences, Anatomy And Physiology Keywords: light; circadian; melatonin

Online: 1 December 2020 (16:06:08 CET)

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Preprint REVIEW | doi:10.20944/preprints201704.0161.v1

Multifaceted Healthy Benefits of Mangifera Indica L. (Mango): The Inestimable Value of an Orchard Recently Rooted in Sicilian Rural Areas

Marianna Lauricella, Sonia Emanuele, Giuseppe Calvaruso, Michela Giuliano, Antonella D'Anneo

Subject: Biology And Life Sciences, Horticulture Keywords: Mangifera indica L. fruit; phytochemicals; nutraceutical properties; mangiferin

Online: 25 April 2017 (16:33:54 CEST)

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Preprint REVIEW | doi:10.20944/preprints202003.0001.v2

Coronavirus Disease 2019 – COVID-19

Kuldeep Dhama, Khan Sharun, Ruchi Tiwari, Shubhankar Sircar, Sudipta Bhat, Yashpal Singh Malik, Karam Pal Singh, Wanpen Chaicumpa, D. Katterine Bonilla-Aldana, Alfonso J. Rodriguez-Morales

Subject: Medicine And Pharmacology, Epidemiology And Infectious Diseases Keywords: emerging coronavirus; 2019-nCoV; SARS-CoV-2; COVID-19; diagnosis; vaccines; therapy; one health

Online: 13 April 2020 (02:29:00 CEST)

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Preprint ARTICLE | doi:10.20944/preprints201803.0102.v2

Increasing of Strength of FDM (FFF) 3D Printed Parts by Influencing on Temperature-Related Parameters of the Process

Vladimir E. Kuznetsov, Alexey N. Solonin, Azamat G. Tavitov, Oleg D. Urzhumtsev, Anna H. Vakulik

Subject: Chemistry And Materials Science, Polymers And Plastics Keywords: additive manufacturing; desktop 3D printing; fused deposition modeling; fused filament fabrication; polylactic acid; anisotropy; interlayer bonds; mechanical strength; digital fabrication

Online: 9 April 2018 (10:33:56 CEST)

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Preprint REVIEW | doi:10.3390/sci1020037

Thermoelectric Materials—Strategies for Improving Device Performance and Its Medical Applications

Palanisamy MohanKumar, Veluru Jagadeesh Babu, Arjun Subramanian, Aishwarya Bandla, Nitish Thakor, Seeram Ramakrishna, He Wei

Subject: Chemistry And Materials Science, Electronic, Optical And Magnetic Materials Keywords: thermoelectric; figure-of-merit; Peltier; Seebeck; thermoelectric generator; cooling

Online: 9 July 2019 (00:00:00 CEST)

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Preprint ARTICLE | doi:10.20944/preprints201802.0045.v1

New Solvent for Polyamide 66 and its use for Preparing Single-Polymer Composite Coated-Fabric

Mostafa Jabbari, Parviz Rashidi Ranjbar, mikael skrifvars, Dan Åkesson, Mohammad J. Taherzadeh

Subject: Chemistry And Materials Science, Polymers And Plastics Keywords: Polyamide solvent, composite, coated-fabric, Nylon, single-polymer composite, all-polyamide composite coated-fabric

Online: 5 February 2018 (16:19:09 CET)

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Preprint ARTICLE | doi:10.20944/preprints201609.0030.v1

Decision and Coordination of Carbon Emissions Reduction Strategy in a Two-Echelon Supply Chain Considering Vertical Technology Spillovers

Lang XU, Chuanxu WANG, Hui LI

Subject: Social Sciences, Decision Sciences Keywords: carbon emissions reduction; technology spillover; game theory; supply chain coordination

Online: 8 September 2016 (11:39:40 CEST)

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Preprint REVIEW | doi:10.20944/preprints202008.0294.v1

A Review of Agricultural Extension and Advisory Services in sub-Saharan African Countries: Progress with Private Sector Involvement

Christopher Nwafor, Ifeoma Nwafor

Subject: Biology And Life Sciences, Agricultural Science And Agronomy Keywords: approaches; extension services; market system; pluralistic; rural development; smallholder

Online: 13 August 2020 (08:07:40 CEST)

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Preprint ARTICLE | doi:10.20944/preprints201702.0033.v1

Experimental Analysis of Thermal Runaway in 18650 Cylindrical Li-Ion Cells Using an Accelerating Rate Calorimeter

Boxia Lei, Wenjiao Zhao, Carlos Ziebert, Nils Uhlmann, Magnus Rohde, Hans Juergen Seifert

Subject: Engineering, Energy And Fuel Technology Keywords: Li-ion cell; Thermal runaway; Accelerating rate calorimeter (ARC); Pressure Change

Online: 10 February 2017 (16:58:01 CET)

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Preprint REVIEW | doi:10.20944/preprints202103.0704.v1

Telenursing as a New Nursing Paradigm in the 21 Century: A Literature Review

Al Afik, Moses Glorino Rumambo Pandin

Subject: Medicine And Pharmacology, Immunology And Allergy Keywords: Telenursing; Nursing; 21st century paradigm

Online: 29 March 2021 (15:41:11 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202003.0085.v1

Structural Elucidation of SARS-CoV-2 Vital Proteins: Computational Methods Reveal Potential Drug Candidates Against Main Protease, Nsp12 RNA-dependent RNA Polymerase and Nsp13 Helicase

Muhammad Usman Mirza, Matheus Froeyen

Subject: Biology And Life Sciences, Virology Keywords: SARS-CoV-2; COVID-19; CoV-Mpro; CoV-Nsp12 polymerase; CoV-Nsp13 helicase

Online: 5 March 2020 (11:50:45 CET)

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Preprint REVIEW | doi:10.20944/preprints201710.0027.v2

Concentrating Solar Power Tower: Latest Status Report and Survey of Development Trends

Albert Boretti, Stefania Castelletto, Sarim Al-Zubaidy

Subject: Engineering, Energy And Fuel Technology Keywords: renewable energy; concentrated solar power; solar tower; parabolic trough; natural gas boost; thermal energy storage; molten salt; steam; Rankine cycles

Online: 17 November 2017 (03:56:36 CET)

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Preprint REVIEW | doi:10.20944/preprints201803.0239.v1

A Comprehensive Review of the Techniques on Regenerative Shock Absorber Systems

Ran Zhang, Xu Wang, Sabu John

Subject: Engineering, Mechanical Engineering Keywords: regenerative, shock absorber, drive mode, vehicle dynamics, output power, nonlinearity

Online: 28 March 2018 (14:18:30 CEST)

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Preprint ARTICLE | doi:10.20944/preprints201802.0131.v2

Tutorial on EM Algorithm

Loc Nguyen

Subject: Computer Science And Mathematics, Probability And Statistics Keywords: expectation maximum, EM, generalized expectation maximum, GEM, EM convergence

Online: 22 February 2018 (16:28:05 CET)

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Preprint REVIEW | doi:10.20944/preprints201804.0066.v1

Cybercrime and Risks for Cyber Physical Systems: A Review

Abel Yeboah-ofori, Jamal-Deen Abdulai, Ferdinand Katsriku

Subject: Computer Science And Mathematics, Information Systems Keywords: cyber physical systems; cybercrime; risk mitigation; risk management; industrial control systems

Online: 5 April 2018 (06:10:06 CEST)

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Cyber Physical Systems (CPS) is the integration of computation and physical process that makes a complete system such as the physical components, networked systems, embedded computers and software and linking together of devices and sensors for information sharing. Cyber Physical Systems are Smart Systems that comprises of the merging and integration of Industry Control Systems, Critical Infrastructures, Internet of Things (IoT) and Embedded Systems. Major industries such as the Chemical and Industrial Plants, Aviation Systems, National Grid, the Stock Exchange, Military Systems, and others depends heavily on these Cyber Physical Systems for financial and economic growth. The benefits of CPS nationally and globally are in the areas of Manufacturing, Energy, Transport, Healthcare and Communication. Cyber Physical Systems incorporates Physical systems, Digital systems and Human elements on network infrastructures to provide interactive systems. However, these three key components the Physical systems, Digital systems and Human elements may have inherent threats and vulnerabilities on them that may run the risk of being compromise, exploited, attacked or hacked. Cybercriminals in their quest to bring down these systems and may cause disruption of services either for fame, revenge, political motive, economic war, cyber terrorism and cyber war. The study seeks to review the risks that are associated with these three key components Physical systems, Digital systems and Human elements. The study considered four main risk mitigation goals for this purpose, and these are Business Value, Organizational Requirements, Threat Agent and Impact based on the review results. We used Analytical Hierarchical Process (AHP) to determine the relative importance of these goals that contributes to developing cybercrime and rich in CPS. For the results, the prioritized goals are then used to assess the risks using a semi-quantitative approach to determine the net threat level.

Preprint ARTICLE | doi:10.20944/preprints202003.0360.v1

Transcriptional Inhibition of Host Viral Entry Proteins as a Therapeutic Strategy for SARS-CoV-2

Xinchen Wang, Ryan Dhindsa, Gundula Povysil, Anthony Zoghbi, Joshua Motelow, Joseph Hostyk, David Goldstein

Subject: Biology And Life Sciences, Biochemistry And Molecular Biology Keywords: SARS-CoV-2; transcriptional inhibition; COVID-19; drug repurposing; TMPRSS2

Online: 24 March 2020 (14:26:57 CET)

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Preprint ARTICLE | doi:10.20944/preprints201707.0053.v1

Garlic (Allium sativum L.) Growth Parameters as Affected by Different Mulching with Irrigation under Fiche Condition, Ethiopia

Weldemariam Seifu Gessesew, Tsion Yemane Gebreslassie

Subject: Biology And Life Sciences, Agricultural Science And Agronomy Keywords: Black polyethylene, Mulches, Allium sativum, Growth, Grass

Online: 19 July 2017 (22:50:23 CEST)

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Preprint BRIEF REPORT | doi:10.20944/preprints201811.0379.v1

Awareness, Knowledge, Attitude and Practice of Safety Occupants at Residential Houses in Libya

Mufida Mkharem, Nor Mariah Adam, Eris Elianddy Supeni

Subject: Engineering, Mechanical Engineering Keywords: awareness emergency; evacuation time; fire hazard; fire safety; knowledge; Libya

Online: 16 November 2018 (06:56:01 CET)

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Preprint ARTICLE | doi:10.20944/preprints201611.0079.v1

Design and Numerical Analysis of Mixed Compression Inlet of a Shcramjet Engine

Nitish Acharya, Sajan Sharma, Lokesh Silwal, Sudip Bhattrai

Subject: Engineering, Industrial And Manufacturing Engineering Keywords: oblique detonation wave; mixed compression inlet; inlet diffusion; total pressure recovery

Online: 16 November 2016 (09:32:59 CET)

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Preprint REVIEW | doi:10.20944/preprints202009.0650.v1

Plant Growth Promoting Rhizobacterial Biofertilizers for Sustainable Crop Production: The Past, Present, and Future

Becky N. Aloo, Billy A. Makumba, Ernest R. Mbega

Subject: Biology And Life Sciences, Biochemistry And Molecular Biology Keywords: biofertilizers; sustainable agriculture; plant growth-promoting rhizobacteria; microbial formulations

Online: 26 September 2020 (16:48:22 CEST)

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Preprint ARTICLE | doi:10.20944/preprints201802.0103.v1

Small Satellite Cloud Detection Based On Deep Learning and Image Compression

Zhang Zhaoxiang, Akira Iwasaki, Xu Guodong, Song Jianing

Subject: Environmental And Earth Sciences, Space And Planetary Science Keywords: Cloud detection; Deep learning; Image Compression.

Online: 15 February 2018 (16:49:55 CET)

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Preprint ARTICLE | doi:10.20944/preprints202002.0061.v1

Deep Learning Based Drug Screening for Novel Coronavirus 2019-nCov

Haiping Zhang, Konda Mani Saravanan, Yang Yang, Md. Tofazzal Hossain, Junxin Li, Xiaohu Ren, Yanjie Wei

Subject: Medicine And Pharmacology, Medicine And Pharmacology Keywords: Coronavirus; Deep learning; Drug screening; homology modeling; main protease

Online: 5 February 2020 (10:59:09 CET)

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Preprint REVIEW | doi:10.20944/preprints202102.0082.v1

Online Identity Theft, Security Issues, and Reputational Damage

Sopna A/P Sinnathamby Sehgar, Zuriati Ahmad Zukarnain

Subject: Computer Science And Mathematics, Security Systems Keywords: identity theft; cyber-crime; identity fraud; types; techniques

Online: 2 February 2021 (10:31:24 CET)

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Preprint REVIEW | doi:10.20944/preprints201609.0013.v1

Tea Polysaccharides and Their Bioactivities

Ling-Ling Du, Qiu-Yue Fu, Li-Ping Xiang, Xin-Qiang Zheng, Jian-Liang Lu, Jian-Hui Ye, Qing-Sheng Li, Curt Anthony Polito, Yue-Rong Liang

Subject: Biology And Life Sciences, Biochemistry And Molecular Biology Keywords: Camellia sinensis; tea ploysaccharides; chemical composition; antioxidant; antitumors; antihyperglycemia; anti-inflammation

Online: 5 September 2016 (10:19:33 CEST)

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Preprint REVIEW | doi:10.20944/preprints202005.0283.v1

Production and Application of Octenyl Succinic-Modified Starch as Fat Replacer: A Review of Established and Recent Research

Riyan Anggriawan, Ali Maksum, Nurhayati Nurhayati

Subject: Biology And Life Sciences, Biochemistry And Molecular Biology Keywords: fat replacer; octenyl succinic anhydride; OSA starch; starch properties

Online: 17 May 2020 (08:14:12 CEST)

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Preprint COMMUNICATION | doi:10.20944/preprints202006.0044.v1

Major Concerns on the Identification of Bat Coronavirus Strain RaTG13 and Quality of Related Nature Paper

xiaoxu lin, Shizhong Chen

Subject: Biology And Life Sciences, Immunology And Microbiology Keywords: Epidemiology; COVID-19; coronavirus; bat; RaTG13; BtCoV/4991; SARS-CoV-2; Pangolin Coronavirus; next generation sequencing

Online: 5 June 2020 (06:17:26 CEST)

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Preprint ARTICLE | doi:10.20944/preprints201612.0007.v1

Modeling and Kinetics of Bioconversion and Chemical Properties (Wine and Vinegar) from Banana Pulp By-Products

Cyntia Akemi Tanaka, Flávia Imanishi Ruzon, Lucas Caldeirão Rodrigues Miranda, Diego Galvan, Wilma Aparecida Spinosa, Raúl Jorge Hernan Castro-Goméz

Subject: Chemistry And Materials Science, Food Chemistry Keywords: acetic fermentation; alcoholic fermentation; submerged process; volatile compounds; acetic bacteria

Online: 1 December 2016 (10:47:37 CET)

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Preprint ARTICLE | doi:10.20944/preprints202106.0258.v1

An appraisal of the Filipino Catholic Devotion to the Black Nazarene in the light of New Evangelization

Joseph Albert Reyes

Subject: Social Sciences, Anthropology Keywords: Black Nazarene; Popular Devotion; Filipino Catholics; Sacred Liturgy; New Evangelization

Online: 9 June 2021 (11:10:28 CEST)

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Preprint ARTICLE | doi:10.20944/preprints201809.0365.v1

On Bounds of the Sine and Cosine Along Straight Lines on the Complex Plane

Feng Qi

Subject: Computer Science And Mathematics, Analysis Keywords: bound; sine; cosine; horizontal straight line; vertical straight line; complex plane; slope

Online: 19 September 2018 (06:24:07 CEST)

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Preprint ARTICLE | doi:10.20944/preprints201708.0087.v1

Development of Understanding Zero

Attila Krajcsi, Petia Kojouharova, Gabor Lengyel

Subject: Social Sciences, Psychology Keywords: numerical cognition; zero; number status of zero; items based number representation

Online: 25 August 2017 (12:28:23 CEST)

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Preprint REVIEW | doi:10.20944/preprints202010.0569.v1

Important Jamaican Medicinal Plants with Special Reference to their Antiviral Activity

Henry Lowe, Blair Steele, Joseph Bryant, Emadelden Fouad, Ngeh Toyang, Wilfred Ngwa

Subject: Medicine And Pharmacology, Immunology And Allergy Keywords: phytomedicine; viral infections; antivirals; phytoantiviral

Online: 28 October 2020 (08:34:07 CET)

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Preprint ARTICLE | doi:10.20944/preprints202203.0378.v1

Impacts of the COVID-19 Pandemic on Healthcare Services in Malaysia from the Perspective of Healthcare Providers: A Cross-Sectional Analysis

Nicholas Yee Liang Hing, Chin Tho Leong, Ramani Subramaniam Kalianan, Wei Yin Lim, Ching Ee Loo, Yuan Liang Woon

Subject: Public Health And Healthcare, Public Health And Health Services Keywords: COVID-19; pandemic; impact; healthcare; lockdown; movement control order; Malaysia; medical services; dental services; pharmacy services

Online: 29 March 2022 (09:45:10 CEST)

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Preprint BRIEF REPORT | doi:10.20944/preprints202004.0004.v1

Transmission Potential and Severity of COVID-19 in Pakistan

Sohail Raza

Subject: Biology And Life Sciences, Virology Keywords: COVID-19, Pakistan, Economic Losses, Disease Spread, SARS-CoV-2

Online: 1 April 2020 (09:19:30 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202105.0493.v1

Pumice as a Novel Nature Heterogeneous Catalyst for Synthesis of 3,4-dihydropyrimidine-2-(1H)-Ones/Thiones via Biginelli Reaction under Solvent-free Conditions

Lamya H. Al-Wahaibi, Antar A. Abdelhamid, Sayed A. Saber, Nadia A.A. Elkanzi, Ali M. Ali

Subject: Chemistry And Materials Science, Analytical Chemistry Keywords: One pot reaction; 3,4- Dihydropyrimidin-2(1H) ones / thiones and Pumice

Online: 20 May 2021 (13:38:53 CEST)

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Preprint ARTICLE | doi:10.20944/preprints201608.0029.v1

Thermal Analysis of an Industrial Furnace

Mirko Filipponi, Federico Rossi, Andrea Presciutti, Stefania De Ciantis, Beatrice Castellani, Ambro Carpinelli

Subject: Engineering, Industrial And Manufacturing Engineering Keywords: CFD simulation; industrial furnace; heat flux; forging industry; thermal analysis

Online: 3 August 2016 (08:47:21 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202002.0047.v1

Possible Inhibitors of ACE2, the Receptor of 2019-nCoV

Qinghua Cui, Chuanbo Huang, Xiangwen Ji, Wanlu Zhang, Fenghong Zhang, Liang Wang

Subject: Medicine And Pharmacology, Pharmacology And Toxicology Keywords: 2019-nCoV; therapeutic strategies; drug; ACE2

Online: 4 February 2020 (10:59:25 CET)

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Preprint ARTICLE | doi:10.20944/preprints201706.0076.v1

Christian Churches and the Boko Haram Insurgency in Cameroon: Dilemmas and Responses

Michael Kpughe Lang

Subject: Arts And Humanities, Religious Studies Keywords: Cameroon; terrorism; religion; Islam; Boko Haram; Christian churches; peace

Online: 16 June 2017 (05:13:32 CEST)

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Preprint REVIEW | doi:10.20944/preprints201805.0484.v1

Review of Deep Learning Methods in Robotic Grasp Detection

Shehan Caldera, Alexander Rassau, Douglas Chai

Subject: Engineering, Electrical And Electronic Engineering Keywords: deep learning; deep convolutional neural networks; dcnn; convolutional neural networks; cnn; robot learning; transfer learning; robotic grasping; robotic grasp detection; human-robot collaboration

Online: 31 May 2018 (17:27:23 CEST)

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Preprint ARTICLE | doi:10.20944/preprints201706.0088.v1

Control Strategy for Grid Connected Inverters Under Unbalanced Network Conditions - A DOb Based Decoupled Current Approach

Emre Ozsoy, Sanjeevikumar Padmanaban, Lucian Mihet-Popa, Viliam Fedák, Fiaz Ahmad, Rasool Akhtar, Asif Sabanovic

Subject: Engineering, Electrical And Electronic Engineering Keywords: power control; power electronics; pwm inverters; disturbance observer; grid connected system; grid stability; distorted voltage

Online: 19 June 2017 (16:35:26 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202010.0043.v1

ASMD-FSMD Technique for Designing Digital Devices on FPGA

Valery Salauyou

Subject: Computer Science And Mathematics, Algebra And Number Theory Keywords: digital device; finite state machine with datapath; algorithm state machine with datapath; field programmable gate array; design technique; development time; reliability; area; performance

Online: 2 October 2020 (13:54:34 CEST)

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Preprint REVIEW | doi:10.20944/preprints202004.0355.v1

Role of Vitamin D in Pathogenesis and Severity of COVID-19 Infection

Maryam Ghavideldarestani, Maryam Honardoost, Mohammad E. Khamseh

Subject: Medicine And Pharmacology, Epidemiology And Infectious Diseases Keywords: vitamin D; ACE2; diabetes; cardiovascular disease

Online: 20 April 2020 (01:37:43 CEST)

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Preprint ARTICLE | doi:10.20944/preprints201805.0179.v1

Assessment of Green Solvents and Extraction Methods for Biopesticide Preparation from Neem Azadirachta indica Leaves against Oriental Fruit Fly Bactrocera dorsalis (Hendel)

Danila S. Paragas, Kathlia Cruz, Elaida R. Fiegalan

Subject: Chemistry And Materials Science, Applied Chemistry Keywords: rice wash; vinegar; rice wine; Soxhlet; fermentation

Online: 11 May 2018 (09:04:45 CEST)

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Preprint ARTICLE | doi:10.20944/preprints201706.0065.v1

Using the HEXACO Model of Personality to Test the Validity of the Durand Adaptive Psychopathic Traits Questionnaire

Guillaume Durand

Subject: Social Sciences, Psychology Keywords: DAPTQ; adaptive personality; psychometric properties; HEXACO; psychopathic personality traits; confirmatory factor analysis; test-retest validity

Online: 14 June 2017 (07:47:55 CEST)

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Working Paper REVIEW

A Comprehensive Review on Bast Fiber Retting Process for Optimal Performance in Fibers Reinforced Polymer Composites

Ching Hao Lee, Khalina Abdan, Seng Hua Lee, Ming Liu

Subject: Chemistry And Materials Science, Biomaterials Keywords: enzyme; bast fibers; enzymatic retting; characterizations

Online: 26 November 2019 (10:27:02 CET)

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Preprint REVIEW | doi:10.20944/preprints202004.0203.v4

Face Masks Against COVID-19: An Evidence Review

Jeremy Howard, Austin Huang, Zhiyuan Li, Zeynep Tufekci, Vladimir Zdimal, Helene-Mari van der Westhuizen, Arne von Delft, Amy Price, Lex Fridman, Lei-Han Tang, Viola Tang, Gregory L. Watson, Christina E. Bax, Reshama Shaikh, Frederik Questier, Danny Hernandez, Larry F. Chu, Christina M. Ramirez, Anne W. Rimoin

Subject: Medicine And Pharmacology, Immunology And Allergy Keywords: COVID-19; SARS-CoV-2; masks; pandemic

Online: 2 November 2020 (10:18:00 CET)

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The science around the use of masks by the general public to impede COVID-19 transmission is advancing rapidly. Policymakers need guidance on how masks should be used by the general population to combat the COVID-19 pandemic. In this narrative review, we develop an analytical framework to examine mask usage, considering and synthesizing the relevant literature to inform multiple areas: population impact; transmission characteristics; source control; PPE; sociological considerations; and implementation considerations. A primary route of transmission of COVID-19 is via respiratory droplets, and is known to be transmissible from presymptomatic and asymptomatic individuals. Reducing disease spread requires two things: first, limit contacts of infected individuals via physical distancing and other measures, and second, reduce the transmission probability per contact. The preponderance of evidence indicates that mask wearing reduces the transmissibility per contact by reducing transmission of infected droplets in both laboratory and clinical contexts. Public mask wearing is most effective at reducing spread of the virus when compliance is high. The decreased transmissibility could substantially reduce the death toll and economic impact while the cost of the intervention is low. Given the current shortages of medical masks we recommend the adoption of public cloth mask wearing, as an effective form of source control, in conjunction with existing hygiene, distancing, and contact tracing strategies. Because many respiratory droplets become smaller due to evaporation, we recommend increasing focus on a previously overlooked aspect of mask usage: mask-wearing by infectious people ("source control") with benefits at the population-level, rather than mask-wearing by susceptible people, such as health-care workers, with focus on individual outcomes. We recommend that public officials and governments strongly encourage the use of widespread face masks in public, including the use of appropriate regulation.

Preprint REVIEW | doi:10.20944/preprints201608.0045.v1

Risks of Climate Change on the Singapore-Malaysia High Speed Rail System

Sazrul Leena Binti Sa’adin, Sakdirat Kaewunruen, David Jaroszweski

Subject: Engineering, Civil Engineering Keywords: railway infrastructure; high-speed rail; tracks; risk; management and monitoring; climate change; global warming; adaptation; operational readiness

Online: 5 August 2016 (05:11:02 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202001.0157.v3

Exceptional Antioxidant, Non-Cytotoxic Activity of Integral Lemon Pectin from Hydrodynamic Cavitation

Domenico Nuzzo, Laura Cristaldi, Marzia Sciortino, Lorenzo Albanese, Antonino Scurria, Federica Zabini, Claudia Lino, Mario Pagliaro, Francesco Meneguzzo, Marta Di Carlo, Rosaria Ciriminna

Subject: Biology And Life Sciences, Biochemistry And Molecular Biology Keywords: pectin; antioxidant; lemon; flavonoids; hydrodynamic cavitation; IntegroPectin

Online: 31 March 2020 (05:00:13 CEST)

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Preprint ARTICLE | doi:10.20944/preprints201609.0056.v1

The Impacts of Different Green Manure on Soil Microbial Communities and Crop Health

Hongwu Yang, Jiaojiao Niu, Jiemeng Tao, Yabing Gu, Chao Zhang, Siyuan She, Wu Chen, Hongqi Yang, Huaqun Yin

Subject: Biology And Life Sciences, Agricultural Science And Agronomy Keywords: green manure; soil microbial communities; crop health; Illumina sequencing

Online: 18 September 2016 (08:56:53 CEST)

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Preprint REVIEW | doi:10.20944/preprints202003.0197.v2

2019 Novel Coronavirus (COVID-19) Outbreak: A Review of the Current Literature and Built Environment (BE) Considerations to Reduce Transmission

Leslie Dietz, Patrick F. Horve, David Coil, Mark Fretz, Jonathan Eisen, Kevin Van Den Wymelenberg

Subject: Biology And Life Sciences, Virology Keywords: Built Environment (BE); building operations; novel coronavirus; COVID-19; SARS-CoV-2

Online: 20 March 2020 (05:02:44 CET)

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Preprint ARTICLE | doi:10.20944/preprints202201.0209.v1

The Effectiveness of Fiscal Policy on Economic Growth in South Africa: An Empirical Analysis

Dumisani Pamba

Subject: Business, Economics And Management, Economics Keywords: Economic Growth; Gross Fixed Capital Formation; Government Expenditure; Government Deficit; Vector Auto-Regression and South Africa

Online: 14 January 2022 (11:36:07 CET)

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Preprint REVIEW | doi:10.20944/preprints202009.0276.v1

Biosynthesis of Lemongrass Essential Oil and the Underlying Mechanism for Its Insecticidal Activity

Mohammad Mukarram, M. Masroor A. Khan, Andleeb Zehra, Sadaf Choudhary, Tariq Aftab, M. Naeem

Subject: Biology And Life Sciences, Plant Sciences Keywords: Citral; essential oil; integrated pest management; insect-repellent; lemongrass; MEP pathway; mevalonate pathway

Online: 13 September 2020 (11:30:41 CEST)

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Working Paper REVIEW

Impact of El Niño and La Niña on Agriculture in Ethiopia: Implications for El Niño and La Niña Adaptation and Food Security in Ethiopia

Abadi Berhane, Teklay Tesfay

Subject: Environmental And Earth Sciences, Atmospheric Science And Meteorology Keywords: El Niño; La Niña; statistical indices; climate change adaptation; Ethiopia

Online: 3 September 2020 (15:33:05 CEST)

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Preprint ARTICLE | doi:10.20944/preprints201608.0215.v1

The Novelty of Infinite Series for the Complete Elliptic Integral of the First Kind

Ali Yunus Rohedi, Yono Hadi Pramono, Basuki Widodo, Eddy Yahya

Subject: Computer Science And Mathematics, Algebra And Number Theory Keywords: integral form; infinite series; modulus function; transformation function

Online: 26 August 2016 (12:57:10 CEST)

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Preprint ARTICLE | doi:10.20944/preprints201612.0138.v1

Vibration Damping Analysis of Lightweight Structures in Machine Tools

Francesco Aggogeri, Alberto Borboni, Angelo Merlo, Nicola Pellegrini, Raffaele Ricatto

Subject: Engineering, Mechanical Engineering Keywords: hybrid materials; machine tool structures; modal analysis; machine tool kinematics; aluminium metal foams; aluminium corrugated sandwiches; CFRP materials; FE simulations; damping

Online: 29 December 2016 (07:36:15 CET)

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Preprint ARTICLE | doi:10.20944/preprints202010.0006.v1

What Can Local Transfer Entropy Tell us About Phase-amplitude Coupling in Electrophysiological Signals?

Ramón Martínez-Cancino, Arnaud Delorme, Johanna Wagner, Kenneth Kreutz-Delgado, Roberto C. Sotero, Scott Makeig

Subject: Biology And Life Sciences, Biochemistry And Molecular Biology Keywords: Phase amplitude coupling; cross frequency coupling; information theory; transfer entropy

Online: 1 October 2020 (08:59:48 CEST)

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Preprint ARTICLE | doi:10.20944/preprints201812.0320.v1

Land Use Land Cover Changes and Their Impact on the Lake Ecosystem of the Central Rift Valley of Ethiopia

Eyasu Elias, Weldemariam Seifu Gessesew, Bereket Tesfaye, Wondewosen Girmay

Subject: Environmental And Earth Sciences, Environmental Science Keywords: Central Rift Valley, Ethiopia, Landsat images, Lake, land use/land cover

Online: 27 December 2018 (10:49:16 CET)

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Preprint REVIEW | doi:10.20944/preprints201612.0119.v1

Food Additives and Contaminants: Effects on Human Gut Microbiota—A Review

Paula Roca-Saavedra, Veronica Mendez-Vilabrille, Jose Manuel Miranda, Alexandre Lamas, Carolina Nebot, Alejandra Cardelle-Cobas, Carlos M. Franco, Alberto Cepeda

Subject: Medicine And Pharmacology, Gastroenterology And Hepatology Keywords: antibiotic; bacteroidetes; dietary emulsifier; firmicutes; food additive; gut microbiota; non-nutritive sweetener; proteobacteria

Online: 23 December 2016 (11:21:40 CET)

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Preprint REVIEW | doi:10.20944/preprints202004.0005.v1

SARS-CoV-2/COVID-19: Viral Genomics, Epidemiology, Vaccines, and Therapeutic Interventions

Mohammed Uddin, Farah Mustafa, Tahir A. Rizvi, Tom Loney, Hanan Al Suwaidi, Ahmad Al Marzouqi, Afaf Kamal Eldin, Nabeel Alsabeeha, Thomas E. Adrian, Cesare Stefanini, Norbert Nowotny, Alawi Alsheikh-Ali, Abiola C. Senok

Subject: Biology And Life Sciences, Virology Keywords: SARS-CoV-2; COVID-19; Coronavirus; Pandemic; Viral Genomics

Online: 1 April 2020 (09:22:38 CEST)

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Preprint ARTICLE | doi:10.20944/preprints201910.0178.v1

Essential Oils with High Activity Against Stationary Phase Bartonella Henselae

Xiao Ma, Wanliang Shi, Ying Zhang

Subject: Medicine And Pharmacology, Pharmacology And Toxicology Keywords: essential oils; Bartonella henselae; persisters; stationary phase; antimicrobial activity

Online: 16 October 2019 (05:18:55 CEST)

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Bartonella henselae is a fastidious Gram-negative intracellular bacterium which can cause cat scratch disease, endocarditis in humans and animals as well as other complications, leading to acute or chronic infections. The current treatment for Bartonella infections is not very effective due to antibiotic resistance and also persistence. To develop better therapies for persistent and chronic Bartonella infections, in this study, with the help of SYBR Green I/PI viability assay, we performed a high-throughput screening of an essential oil library against stationary phase B. henselae. We successfully identified 32 essential oils that had high activity, including four essential oils extracted from Citrus plants, three from Origanum, three from Cinnamomum, two from Pelargonium and two from Melaleuca, as well as frankincense, ylang ylang, fir needle, mountain savory (winter), citronella, spearmint, elemi, vetiver, clove bud, allspice and cedarwood essential oils. The minimal inhibitory concentration (MIC) determination of these 32 top hits indicated they were not only active against stationary phase non-growing B. henselae but also had good activity against log phase growing B. henselae. The time-kill curve by drug exposure assay showed 13 active hits, including essential oils of oregano, cinnamon bark, mountain savory (winter), cinnamon leaf, geranium, clove bud, allspice, geranium bourbon, ylang ylang, citronella, elemi and vetiver, could eradicate all stationary phase B. henselae cells within 7 days at the concentration of 0.032% (v/v). Two active ingredients, carvacrol and cinnamaldehyde, of oregano and cinnamon bark essential oils, respectively, were shown to be very active against stationary phase B. henselae such that they were able to eradicate all the bacterial cells even at the concentration ≤ 0.01% (v/v). Our finding of active essential oils may help to develop more effective treatments for persistent Bartonella infections.

Preprint REVIEW | doi:10.20944/preprints202004.0377.v1

The Dynamics of Humoral Immune Responses Following SARS-CoV-2 Infection and the Potential for Reinfection

Paul Kellam, Wendy Barclay

Subject: Biology And Life Sciences, Virology Keywords: COVID-19; SARS-CoV-2; immune response; antibodies

Online: 21 April 2020 (06:56:12 CEST)

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Preprint HYPOTHESIS | doi:10.20944/preprints201607.0014.v1

Investors Perception Towards Investment With Reference To Modern And Other Traditional Tools

Bhavesh Kumar Rathod, V Asha, J Gajendra Naidu

Subject: Business, Economics And Management, Accounting And Taxation Keywords: EVA, EPS, CVA, Respondent

Online: 8 July 2016 (11:17:37 CEST)

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Preprint ARTICLE | doi:10.20944/preprints201805.0223.v1

Multibody Simulation for the Vibration Analysis of a Turbocharged Diesel Engine

Enrico Armentani, Francesco Caputo, Luca Esposito, Roberto Citarella

Subject: Engineering, Mechanical Engineering Keywords: vibration analysis; FEM; multibody

Online: 16 May 2018 (07:36:50 CEST)

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Preprint ARTICLE | doi:10.20944/preprints201608.0149.v1

Estimation of Chlorophyll‐a Concentration and Trophic States for an Inland Lake from Landsat 8 OLI Data: A Case of Nalban Lake of East Kolkata Wetland, India

Pulak Patra, Sourabh Kumar Dubey, Raman Kumar Trivedi, Sanjeev Kumar Sahu, Sangram Keshari Rout

Subject: Environmental And Earth Sciences, Environmental Science Keywords: landsat 8 OLI; Nalban Lake; East Kolkata Wetland; chlorophyll-a prediction; study points; validation points

Online: 15 August 2016 (13:51:19 CEST)

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Preprint ARTICLE | doi:10.20944/preprints201909.0321.v1

Sociology and History: Contained Dialogues

Sandro Serpa, Carlos Miguel Ferreira

Subject: Social Sciences, Sociology Keywords: sociology; history; interdisciplinary dialogue

Online: 29 September 2019 (04:40:24 CEST)

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