Preprint Review Version 1 Preserved in Portico This version is not peer-reviewed

Food Additives and Contaminants: Effects on Human Gut Microbiota—A Review

Version 1 : Received: 22 December 2016 / Approved: 23 December 2016 / Online: 23 December 2016 (11:21:40 CET)

How to cite: Roca-Saavedra, P.; Mendez-Vilabrille, V.; Miranda, J.M.; Lamas, A.; Nebot, C.; Cardelle-Cobas, A.; Franco, C.M.; Cepeda, A. Food Additives and Contaminants: Effects on Human Gut Microbiota—A Review. Preprints 2016, 2016120119. https://doi.org/10.20944/preprints201612.0119.v1 Roca-Saavedra, P.; Mendez-Vilabrille, V.; Miranda, J.M.; Lamas, A.; Nebot, C.; Cardelle-Cobas, A.; Franco, C.M.; Cepeda, A. Food Additives and Contaminants: Effects on Human Gut Microbiota—A Review. Preprints 2016, 2016120119. https://doi.org/10.20944/preprints201612.0119.v1

Abstract

Gut bacteria play an important role in several metabolic processes and human diseases, such as obesity and its co-morbidities, like fatty liver disease, insulin resistance/diabetes and cardiovascular events. Among several factors, dietary patterns, probiotics, prebiotics, synbiotics, antimicrobials and non-dietary factors, such as stress, age, exercise and climatic conditions, can dramatically impact the human gut microbiota diversity and equilibrium. However, the effect of minor food constituents, including food additives and trace contaminants, on human gut microbiota has received less attention. Consequently, the present review aimed to provide an objective perspective of the current knowledge regarding the impacts of minor food constituents on human gut microbiota and consequently, on human health.

Keywords

antibiotic; bacteroidetes; dietary emulsifier; firmicutes; food additive; gut microbiota; non-nutritive sweetener; proteobacteria

Subject

Medicine and Pharmacology, Gastroenterology and Hepatology

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