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Preprint ARTICLE | doi:10.20944/preprints202312.0183.v1

Saturated Boiling Enhancement of Novec-7100 on Microgroove Surfaces with Anisotropic Properties

Ho-Ching Lin, Cheng-Hsin Kang, Hui-Chung Cheng, Tien-Li Chang, Ping-Hei Chen

Subject: Mechanical Engineering, Engineering Keywords: Pool boiling; Femtosecond laser; Anisotropic properties; Bubble dynamics; Heat transfer coefficient; Critical heat flux

Online: 4 December 2023 (12:17:43 CET)

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Preprint ARTICLE | doi:10.20944/preprints202312.0201.v1

Educational Status as a Mediator of Intergenerational Social Mobility in Europe: A Positional Analysis Approach

Glykeria Stamatopoulou, Eva Tsouparopoulou, Maria Symeonaki

Subject: Sociology, Social Sciences Keywords: intergenerational social mobility; Markov processes; ESS

Online: 4 December 2023 (12:10:43 CET)

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Preprint COMMUNICATION | doi:10.20944/preprints202312.0202.v1

Membrane Separation of Chicken Byproduct Hydrolysate for Up-Concentration of Bioactive Peptides

Janka Dibdiakova, Josipa Matic, Sileshi Gizachew Wubshet, Bjørn Rusten, Lelum Duminda Manamperuma, Eilen Arctander Vik

Subject: Biomaterials, Chemistry And Materials Science Keywords: bioactive peptides; enzymatic protein hydrolysis; membrane filtration; purification; LC-OCD.

Online: 4 December 2023 (12:03:34 CET)

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Preprint ARTICLE | doi:10.20944/preprints202312.0148.v2

IoT-Integrated Vertical Fruit Display for Retail Store

Mohammed Arfat Raihan Chowdhury, Md Rakibul Hasan

Subject: Industrial And Manufacturing Engineering, Engineering Keywords: food loss; fruit display; IoT; retail

Online: 4 December 2023 (11:59:06 CET)

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Preprint ARTICLE | doi:10.20944/preprints202312.0200.v1

Seepage Actions and Their Consequences on the Support Scheme of Deep-Buried Tunnels Constructed in Soft Rock Strata

Wadslin Frenelus, Hui Peng, Jingyu Zhang

Subject: Civil Engineering, Engineering Keywords: deep-buried tunnels; seepage actions; soft rocks; Mogi-Coulomb strain criterion; strain-softening model; analytical models; tunnel safety and stability

Online: 4 December 2023 (11:58:17 CET)

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Preprint ARTICLE | doi:10.20944/preprints202312.0168.v1

Cancer Screening in Angolan Individuals Using Tumor Marker Tests at Mediag, Luanda-Angola

Edson Kutelela Cassinela, Lourenço Quixari, Silvana da Rocha Silveira, Cruz dos Santos Sebastião, António Armando, Carlos Pinto-Sousa, José Fernando, Manuel Sangombe Epalanga, Euclides Nenga Manuel Sacomboio

Subject: Oncology And Oncogenics, Medicine And Pharmacology Keywords: tumor marker; screening; Angolan population

Online: 4 December 2023 (11:40:55 CET)

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Preprint ARTICLE | doi:10.20944/preprints202312.0164.v1

2-Propanol Activation on the Low Index Co₃O₄ Surfaces: A Comparative Study Using Molecular Dynamics Simulations

Amir Hossein Omranpoor, Stephane Kenmoe

Subject: Surfaces, Coatings And Films, Chemistry And Materials Science Keywords: activation; active sites; oxidation; surfaces; temperature; structure to activity

Online: 4 December 2023 (11:39:30 CET)

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Preprint ARTICLE | doi:10.20944/preprints202310.1841.v3

The Impact of Electric Vehicle Charging Stations on Light Duty Electric Vehicle Adoption and Rebates in California

Makuochukwu Okoma

Subject: Government, Social Sciences Keywords: Electric Vehicle (EV); Electric Vehicle Charging Stations; California; Rebates; Adoption

Online: 4 December 2023 (11:38:26 CET)

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Preprint COMMUNICATION | doi:10.20944/preprints202312.0165.v1

Challenges in the Forecasting of Severe Typhoon Koinu in 2023

P.W. Chan, Y.H. He

Subject: Atmospheric Science And Meteorology, Environmental And Earth Sciences Keywords: tropical cyclone; track; intensity; wind; rainfall

Online: 4 December 2023 (11:35:44 CET)

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Preprint ARTICLE | doi:10.20944/preprints202312.0177.v1

Transport of Riverine Microplastics in the Arctic Ocean

Elena Golubeva, Marina Gradova

Subject: Pollution, Environmental And Earth Sciences Keywords: Siberian Arctic Seas; microplastic polution; Arctic rivers; numerical modeling

Online: 4 December 2023 (11:33:55 CET)

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Preprint ARTICLE | doi:10.20944/preprints202312.0181.v1

Model Simulation and Rheological Research on Crosslinking Behavior of Polyethylene Resin

Xuelian Chen, Qigu Huang

Subject: Industrial And Manufacturing Engineering, Engineering Keywords: polyethylene; crosslink; polymeric structure; model simulation; rheological method

Online: 4 December 2023 (11:31:37 CET)

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Preprint ARTICLE | doi:10.20944/preprints202312.0198.v1

Gamification and new approaches in Engineering Education

Serafeim Triantafyllou

Subject: Computer Science, Computer Science And Mathematics Keywords: gamification; motivational theories; engineering education; micro-credentials &; engineering

Online: 4 December 2023 (11:29:39 CET)

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Preprint ARTICLE | doi:10.20944/preprints202312.0166.v1

Knowledge Representation of Age-Related Diseases under Innate and Adaptative-Immunosenescence Valued Contexts

javier Burgos-Salcedo

Subject: Immunology And Allergy, Medicine And Pharmacology Keywords: Immunosenescence; Knowledge representation; Formal concept Analysis; Age-related diseases

Online: 4 December 2023 (11:27:43 CET)

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Preprint ARTICLE | doi:10.20944/preprints202312.0167.v1

Urinalysis Results and Resistance to Hospital Treatment with Injectable Antimalarials in Angola

Euclides Nenga Manuel Sacomboio, Telma Patrícia Pereira Paulo, Edson Kuatelela Cassinela, Cruz dos Santos Sebastião

Subject: Clinical Medicine, Medicine And Pharmacology Keywords: ; Urinalysis; resistance treatment; injectable antimalarials; sociodemographic; clinical

Online: 4 December 2023 (11:27:16 CET)

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Preprint ARTICLE | doi:10.20944/preprints202312.0191.v1

Automated Carbon Footprint Monitoring Systems for a Smart City

Ekaterina Kulakova, Elena Muravyova

Subject: Environmental Science, Environmental And Earth Sciences Keywords: climate change; SCADA-system; carbon footprint; sustainability; urban technology

Online: 4 December 2023 (11:16:17 CET)

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Preprint ARTICLE | doi:10.20944/preprints202312.0190.v1

Real-Time 2D Orthomosaic Mapping from Drone-Captured Images Using Feature-Based Sequential Image Registration

Se-Yun Hwang, Jang Hyun Lee, Chang Su Ha, Minuk Yang, Jae Ho Choi

Subject: Architecture, Building And Construction, Engineering Keywords: two-dimensional (2D) orthomosaic; drone video processing; real-time image registration; sequential registration; scale-invariant feature transform (SIFT); fast library for approximate nearest neighbors (FLANN); random sample consensus (RANSAC)

Online: 4 December 2023 (11:14:13 CET)

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Preprint ARTICLE | doi:10.20944/preprints202312.0186.v1

Advanced Machine Translation with Linguistic-Enhanced Transformer

Richard Patricia, Judith Sadok, Rodolfo Patel

Subject: Artificial Intelligence And Machine Learning, Computer Science And Mathematics Keywords: enhanced machine translation; linguistic syntax; transformer model

Online: 4 December 2023 (10:54:56 CET)

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Preprint REVIEW | doi:10.20944/preprints202312.0185.v1

Antibody Dependent Enhancement (ADE) of Infection into Macrophages Validates the Importance of HERV-K102 Particle Production for Pandemic Preparedness

Marian Laderoute

Subject: Immunology And Allergy, Medicine And Pharmacology Keywords: ADE, HERV-K102, HERV-K HML-2, immunosenescence, foamy macrophages, virus-anti-virus, pandemic preparedness, mRNA COVID-19 vaccines, alpha-fetoprotein antagonists, virus strategies, anti-viral, trained (innate) immunity

Online: 4 December 2023 (10:53:40 CET)

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Preprint ARTICLE | doi:10.20944/preprints202312.0182.v1

Factors Affecting Olive Oil Quality in Traditional Olive Orchards in the Middle East

Arnon Dag, Zipora Tietel, Isaac Zipori

Subject: Agricultural Science And Agronomy, Biology And Life Sciences Keywords: harvesting; oil quality; olive; traditional cultivation

Online: 4 December 2023 (10:29:08 CET)

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Preprint INTERESTING IMAGES | doi:10.20944/preprints202312.0176.v1

An Ectopic Parathyroid Adenoma of the Retropharynx in a Patient with Primary Hyperparathyroidism and Papillary Thyroid Cancer – A Rare Case

Youngjae Lee, Wonyong Baek, Ji-Woong Cho, Jeonghyun Oh

Subject: Otolaryngology, Medicine And Pharmacology Keywords: primary hyperparathyroidism; papillary thyroid carcinoma; ectopic parathyroid

Online: 4 December 2023 (10:19:54 CET)

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Preprint ARTICLE | doi:10.20944/preprints202312.0179.v1

Identification of Genomic Regions Associated with Flowering Traits in Cassava (Manihot esculenta Crantz)

Julius K. Baguma, Ssettumba B. Mukasa, Ephraim Nuwamanya, Titus Alicai, Christopher Abu Omongo, Mildred Ochwo Ssemakula, Alfred Ozimati, Williams Esuma, Michael Kanaabi, Enoch Wembabazi, Yona Baguma, Robert Kawuki

Subject: Plant Sciences, Biology And Life Sciences Keywords: flowering traits; first branching; branching levels; flowering behaviour; functional annotations

Online: 4 December 2023 (10:18:19 CET)

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Preprint ARTICLE | doi:10.20944/preprints202312.0178.v1

Functional and Multi-Omics Analysis of an Optimized CRISPR-Mediated FURIN Depletion in Cultured Pro-Monocytic Cells

Ruiming Chua, Lijin Wang, Roshni Singaraja, Sujoy Ghosh

Subject: Cell And Developmental Biology, Biology And Life Sciences Keywords: myeloid cells; FURIN protease; gene editing; functional assays; genomics; cytokine secretion

Online: 4 December 2023 (10:18:09 CET)

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Preprint REVIEW | doi:10.20944/preprints202312.0180.v1

The Role of Marine n-3 Polyunsaturated Fatty Acids on Inflammatory-Based Disease: The Case of Rheumatoid Arthritis

Cinzia Parolini

Subject: Other, Medicine And Pharmacology Keywords: Fish oil; Inflammation; n-3 PUFAs; Rheumatoid arthritis; Specialized pro-resolving mediators

Online: 4 December 2023 (10:15:43 CET)

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Preprint ARTICLE | doi:10.20944/preprints202312.0172.v1

The Effect of Cross-Sex Fecal Microbiota Transplantation on Metabolism and Hormonal Status in Adult Rats

Andrej Fejes, Paulina Balvoncikova, Dafne Porcel Sanchis, Veronika Borbelyova, Peter Celec, Maria Dzunkova, Roman Gardlík

Subject: Medicine And Pharmacology, Medicine And Pharmacology Keywords: sex differences; testosterone; gut microbiota; microbiome; fecal microbiota transplantation; metabolic disease; cross-sex

Online: 4 December 2023 (10:13:20 CET)

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Preprint ARTICLE | doi:10.20944/preprints202312.0171.v1

Speed Change Pattern Optimization for Improving Electricity Consumption of Electric Bus and Its Verification by Actual Vehicle

Yiyuan Fang, Wei-hsiang Yang, Yushi Kamiya, Takehito Imai, Shigeru Ueki, Masayuki Kobayashi

Subject: Automotive Engineering, Engineering Keywords: energy consumption; efficiency; EV (electric vehicle); simulation; optimization

Online: 4 December 2023 (10:11:59 CET)

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Preprint ARTICLE | doi:10.20944/preprints202312.0170.v1

DHA Content in Milk during Different Lactation Stages

Shaohong Jin, Genna Ba, Han Chen, Hongsheng Du, Panqiao Chen, Ke Zhou, Dian Wang, Pengjie Wang

Subject: Food Science And Technology, Biology And Life Sciences Keywords: DHA-biofortified milk; parity; lactation stage; DHA content; conversion rate

Online: 4 December 2023 (10:10:11 CET)

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Preprint REVIEW | doi:10.20944/preprints202312.0175.v1

A Critical Appraisal of the Protecting Activity of Polyphenolic Antioxidants Against Iatrogenic Effects of Anticancer Chemotherapeutics§

Rosa Purgatorio, Angelina Boccarelli, Leonardo Pisani, Modesto De Candia, Marco Catto, Cosimo Damiano Altomare

Subject: Life Sciences, Biology And Life Sciences Keywords: polyphenols; chemotherapy adjuvants; oxidative stress; cardiac toxicity

Online: 4 December 2023 (10:06:52 CET)

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Preprint ARTICLE | doi:10.20944/preprints202312.0174.v1

SARS-CoV-2 Intra-host Evolution Is Not Favoured by Immune System Deficiencies

Laura Manuto, Martina Bado, Marco Cola, Elena Vanzo, Maria Antonello, Giorgia Mazzotti, Monia Pacenti, Giampaolo Cordioli, Lolita Sasset, Anna Maria Cattelan, Stefano Toppo, Enrico Lavezzo

Subject: Virology, Biology And Life Sciences Keywords: SARS-CoV-2 genomic variability; viral quasispecies; immunocompromised subjects; intra-host

Online: 4 December 2023 (10:04:22 CET)

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Preprint REVIEW | doi:10.20944/preprints202312.0169.v1

The Conventional and Breakthrough Tool for the Study of L-glutamate Transporters

Kanako Takahashi, Kaoru Sato

Subject: Neuroscience And Neurology, Medicine And Pharmacology Keywords: Xenopus oocyte; glutamate transporter; EAAT2; two-electrode voltage clamp; overexpression; excitotoxicity

Online: 4 December 2023 (10:03:27 CET)

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Preprint ARTICLE | doi:10.20944/preprints202312.0100.v1

Meteorological Signal on Hydrodynamics in the Ilha Grande and Sepetiba Bays: Lag Effects and Coastal Currents

Nair Emmanuela da Silveira Pereira, Suzana Beatriz Vinzón, Marcos Nicolás Gallo, Mariela Gabioux

Subject: Oceanography, Environmental And Earth Sciences Keywords: numerical modelling; non-tidal fluctuations; remote meteorological effects; riemann’ s invariants; Ilha Grande and Sepetiba bays.

Online: 4 December 2023 (09:45:06 CET)

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Preprint ARTICLE | doi:10.20944/preprints202312.0099.v1

Nature - Based Solutions: Restoring Mangroves for Shoreline Protection and Other Ecosystem Services at Gazi Bay, Kenya

Gladys Kinya, James Gitundu Kairo, Rossa Ngendo Nyoike, Josphat Nguu Gachoki, Brian Kiiru Githinji, Michael Njoroge Githaiga

Subject: Ecology, Evolution, Behavior And Systematics, Biology And Life Sciences Keywords: mangrove restoration; modified restoration tools; nature-based solutions; disaster risk management, shoreline erosion; climate change, Gazi; Kenya

Online: 4 December 2023 (09:43:08 CET)

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Preprint ARTICLE | doi:10.20944/preprints202312.0102.v1

Switching to Vortioxetine in Patients with Poor- Tolerated Antidepressant-Related Sexual Dysfunction in Clinical Practice: A 3-Month Prospective Real-Life Study

Angel L. Montejo, Froilan Sanchez-Sanchez, Rubén De Alarcón, Juan Matías, Benjamin Cortés, Claudia Matos, Tomás Martín-Pinto, Peñitas Rios, Nerea González-García, José María Acosta

Subject: Psychiatry And Mental Health, Medicine And Pharmacology Keywords: Sexual Dysfunction; antidepressant; vortioxetine; depression; sexuality

Online: 4 December 2023 (09:17:50 CET)

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Treatment-emergent sexual dysfunction (TESD) is one of the most frequent and persistent adverse effects of antidepressant medication. Sexual dysfunction (SD) secondary to SSRIs occurs in >60% of sexually active patients and >80% of healthy volunteers, with this causing treatment discontinuation in >35% of patients. However, this factor is rarely addressed in routine examinations, and only 15%-30% of these events are spontaneously reported. A strategy of switching to a different non-serotonergic antidepressant could involve a risk of relapse or clinical worsening due to a lack of serotonergic activity. Vortioxetine appears to have less impact on sexual function due to its multimodal mechanism of action. No studies have been published on the effectiveness of switching to vortioxetine in patients with poorly tolerated long-term antidepressant-related SD at naturalistic settings. Study objectives: To determine the effectiveness of switching to vortioxetine due to SD in a routine clinical practice setting. Methodology: observational pragmatic and naturalistic study to determinate the effectiveness of the switch to vortioxetine (mean dosage 13.11±4.03) in 74 patients aged 43.1 ± 12.65 ( 54% males) at risk of discontinuing treatment due to sexual dysfunction. The SALSEX Scale was applied at two moments: baseline visit and after 3 months of follow-up. Results. The global Sexual Dysfunction (SD) measured with the SALSEX Scale, decreased significantly from baseline visit (10.32; SD 2.73) to follow-up visit (3.78; SD 3.68) p<0.001. There was a significant improvement ( p<0.001) at the endpoint including decreased libido, delay of orgasm, anorgasmia and arousal difficulties in both sexes. After switching to Vortioxetine, 83.81% of patients experienced sexual function improvement (43.2% felt greatly improved). Most patients (83.3%) who switched to vortioxetine continued treatment after the follow-up visit. 58.1% of patients showed an improvement in depressive symptoms from baseline visit. Conclusion. Switching to vortioxetine is an effective and reliable strategy to treat patients with poor tolerated previous antidepressant -related sexual dysfunction in the real-life clinical settings.

Preprint ARTICLE | doi:10.20944/preprints202312.0103.v1

Associations of Broader Parental Factors with Children’s Happiness and Weight-Status through Child Food Intake, Physical Activity, and Screen Time: A Longitudinal Modeling Analysis of the South Korean Families

Kay W Kim, Jan L Wallander, Bokyung Kim

Subject: Psychology, Social Sciences Keywords: play; stress; happiness; dietary intake; physical activity; weight status; parent; child ;

Online: 4 December 2023 (09:06:25 CET)

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Preprint ARTICLE | doi:10.20944/preprints202312.0076.v1

Aesthetics in Removable Partial Dentures: Modification of the Proximal Plate and Retentive Lamellae in Kennedy's Second Classes

Saverio Ceraulo

Subject: Dentistry And Oral Surgery, Medicine And Pharmacology Keywords: removable prosthesis; ; prosthesis modification; ; aesthetics, retention

Online: 4 December 2023 (08:36:13 CET)

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Preprint ARTICLE | doi:10.20944/preprints202312.0074.v1

Formulation, Biochemical Characterization and Shelf-Life Study of YoAlp® Whey Based Beverage Containing Fruits Juices Produced in Aosta Valley

Mathieu Merlet, Tania Flutto, Rita Pramotton, Simona Zenato, Luca Vernetti-Prot, Sabina Valentini

Subject: Food Science And Technology, Biology And Life Sciences Keywords: functional beverages; bioactive peptides; polyphenols; probiotic; autochthonous fermented milk

Online: 4 December 2023 (08:34:17 CET)

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Preprint ARTICLE | doi:10.20944/preprints202312.0101.v1

Influence of the Arrangement of the Cells/Modules of a Traction Battery on the Spread of Fire in Case of Thermal Runaway

Ana Olona, Luis Castejón

Subject: Mechanical Engineering, Engineering Keywords: Thermal Runaway; pouch cell; chemical composition analysis; structural analysis; thermal failure test

Online: 4 December 2023 (08:29:25 CET)

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Preprint ARTICLE | doi:10.20944/preprints202312.0075.v1

Towards a European Facility for Ground-Based Radar Observations of Near-Earth Objects

Giuseppe Pupillo, Simona Righini, Roberto Orosei, Claudio Bortolotti, Giuseppe Maccaferri, Mauro Roma, Marco Mastrogiuseppe, Tonino Pisanu, Luca Schirru, Stefano Cicalo', Antonio Tripodo, Jorma Harju, Antti Penttilä, Anne K. Virkki, Uwe Bach, Alexander Kraus, Alessio Margheri, Riccardo Ghiani, Maria N. Iacolina, Giuseppe Valente, Detlef Koschny, Richard Moissl, Gunther Sessler

Subject: Astronomy And Astrophysics, Physical Sciences Keywords: radar; near-Earth Objects; asteroids; planetary defense

Online: 4 December 2023 (08:27:04 CET)

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Preprint ARTICLE | doi:10.20944/preprints202312.0148.v1

IoT-Integrated Vertical Fruit Display for Retail Store

Md Rakibul Hasan, Mohammed Arfat Raihan Chowdhury

Subject: Industrial And Manufacturing Engineering, Engineering Keywords: food loss; fruit display; IoT; retail

Online: 4 December 2023 (07:54:36 CET)

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Preprint ARTICLE | doi:10.20944/preprints202312.0143.v1

Achievement of Food Waste Recycling Law in Japan With Reference to SDG12.3

Tomoko Okayama, Kohei Watanabe

Subject: Waste Management And Disposal, Environmental And Earth Sciences Keywords: SDG12.3; food waste; food waste recycling law; recycling as feed; food waste reduction promotion act; Japan

Online: 4 December 2023 (07:53:53 CET)

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Preprint ARTICLE | doi:10.20944/preprints202312.0140.v1

Larvicidal Potential of Silver Nanoparticles Synthesized From Ocimum gratissimum Leaf Extracts Against Anopheles Mosquito

Adedamola Sunmonu, Nzube Ekpunobi

Subject: Biology And Biotechnology, Biology And Life Sciences Keywords: Ocimum gratissimum; silver nano-particle larvicides; Anopheles; Insecticide-resistant mosquito

Online: 4 December 2023 (07:52:48 CET)

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Preprint ARTICLE | doi:10.20944/preprints202312.0163.v1

A Novel Orthogonally High Isolation CPW Fed UWB MIMO Antenna for IoT Applications

Muhammad Zahid, Nirman Bhowmike, Zaeem Mazhar, Asma Ejaz, Sultan Shoaib, Yasar Amin

Subject: Electrical And Electronic Engineering, Engineering Keywords: UWB; MIMO; Internet of thing; high isolation

Online: 4 December 2023 (07:51:16 CET)

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Preprint ARTICLE | doi:10.20944/preprints202312.0141.v1

Project-based Digital Science Module (DSM) An Analysis of Students' Self-regulated learning and Scientific Writing Ability

Abd. Mukhid, Rony Harianto, Rufii Rufii

Subject: Education, Social Sciences Keywords: Digital module, self-regulated, writing ability

Online: 4 December 2023 (07:49:39 CET)

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Preprint ARTICLE | doi:10.20944/preprints202312.0157.v1

Assessing Twenty-Two Life-Changing Events of Emily Howard Jennings Stowe with a Unique Narrative Research Process

Carol Nash

Subject: History, Arts And Humanities Keywords: Emily Stowe; Canada; female school principal; female physician; suffragette; narrative research

Online: 4 December 2023 (07:47:48 CET)

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Preprint ARTICLE | doi:10.20944/preprints202312.0159.v1

Flower Strips Increase Land Efficiency Use in Associated Crops: Broccoli-Lettuce

Carlos Alberto Marcillo-Paguay, Eliana Gisela Revelo-Gómez, Erika Paola Igua-Urbano, Eliana Martinez

Subject: Agricultural Science And Agronomy, Biology And Life Sciences Keywords: Lettuce-Broccoli intercropping; organic agriculture; diversification practices; agroecology.

Online: 4 December 2023 (07:45:39 CET)

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Preprint ARTICLE | doi:10.20944/preprints202312.0142.v1

Finance Digitization in Low- and Lower-Middle-Income Countries: An Empirical Investigation and Prediction of Future Outcomes

Ladi Busuyi Daodu, Amiya Bhaumik

Subject: Finance, Business, Economics And Management Keywords: digitalisation; global; fintech; mobile money; financial inclusion

Online: 4 December 2023 (07:44:29 CET)

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Previous studies have suggested that digitization of finance leads to growth in the economy in several middle- and high-income countries, but research in low- and lower-middle-income countries (LLMICs) remains limited. This research aimed to examine the trends, barriers, relationships, and prospects of finance digitization in LLMICs. This study used analytical and descriptive cross-sectional study designs. Sixty-six countries were purposively selected based on the available data on the Global Findex and the World Development Indicators databases. Descriptive analysis was used to identify the trends in the finance digitization indicators, correlation analysis was used to assess the nature of the association between finance digitization and the economy, and exponential smoothing was used to predict future outcomes in digital finance. The results indicated that the adoption and utilization of finance digitization increased in these countries, but the growth rates varied by region and income group. Low-income countries reported the highest rates of subscriptions to digital finance accounts and storing money in digital accounts, while lower-middle-income countries (LMICs) reported higher rates of inbound/outbound digital transactions, borrowings, and savings using digital channels. Sub-Saharan Africa reported the highest rates of digital finance account subscriptions, digital savings, and digital borrowings, while Europe and Central Asia reported the highest rates of in/out digital transactions. Barriers to digitization in these countries included poor access to the internet, high cost of digital finance products, and lack of a mobile phone, with low-income countries facing more challenges. The analysis revealed a negative significant relationship between finance digitization and Gross National Income growth and a positive significant correlation between finance digitization and other economic growth indicators (gross savings and Gross Domestic Product). Finance digitization was predicted to continue to rise in these countries for the next decade. The study recommended that policymakers should promote the adoption of digital finance and address the barriers and risks of finance digitization in LLMICs, as it had positive effects on economic growth.

Preprint ARTICLE | doi:10.20944/preprints202312.0153.v1

Survey of Veterinarians’ Experiences and Perceptions of the Diagnosis of Spironucleosis in Game Birds

Matthew Hylands, Natasha Hands, Michael Clark, Hany Elsheikha

Subject: Parasitology, Biology And Life Sciences Keywords: spironucleosis; spironucleus; hexamitosis; protozoan parasites; game birds; diagnosis; questionnaires

Online: 4 December 2023 (07:42:59 CET)

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Preprint ARTICLE | doi:10.20944/preprints202312.0156.v1

CMIP5 Decadal Precipitation at Catchment Level

Md Monowar Hossain, A. H. M. Faisal Anwar, Nikhil Garg, Mahesh Prakash, Mohammed Abdul Abdul Bari

Subject: Other, Environmental And Earth Sciences Keywords: cmip5; decadal; precipitation; prediction; catchment; multi-model

Online: 4 December 2023 (07:41:48 CET)

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Preprint ARTICLE | doi:10.20944/preprints202312.0150.v1

Low-sidelobe Imaging Method Utilizing Improved Spatially Variant Apodization for Forward-Looking Sonar

Lu Yan, Juan Yang, Feng Xu, Shengchun Piao

Subject: Marine Engineering, Engineering Keywords: forward-looking imaging sonar; spatially variant apodization; low-sidelobe; main lobe resolution; image quality

Online: 4 December 2023 (07:40:23 CET)

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Preprint ARTICLE | doi:10.20944/preprints202312.0158.v1

Analyzing Data Theft Ransomware Traffic Patterns Using BERT

Gabriela Almeida, Felipe Vasconcelos

Subject: Computer Science, Computer Science And Mathematics Keywords: Ransomware Evolution; Data Theft; Network Traffic Analysis; BERT Model; Cybersecurity Adaptation

Online: 4 December 2023 (06:58:59 CET)

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Preprint ARTICLE | doi:10.20944/preprints202312.0155.v1

Entropic Density Functional Theory

Ahmad Yousefi, Ariel Caticha

Subject: Condensed Matter Physics, Physical Sciences Keywords: density functional theory; Hohenberg-Kohn theorem; entropic inference; method of maximum entropy; inhomogeneous fluids

Online: 4 December 2023 (06:58:45 CET)

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Preprint ARTICLE | doi:10.20944/preprints202312.0149.v1

Study of Bluetongue Virus (BTV) and Epizootic Hemorrhagic Disease Virus (EHDV) circulation and vectors at the the Municipal Parks and Zoobotanical Foundation of Belo Horizonte, Minas Gerais, Brazil (FPMZB-BH)

Eduardo Alves Caixeta, Mariana Andrioli Pinheiro, Victoria Souza Lucchesi, Anna Gabriella Guimarães Oliveira, Grazielle Cossenzo Florentino Galinari, Herlandes Penha Tinoco, Carlyle Mendes Coelho, Zélia Inês Portela Lobato

Subject: Virology, Biology And Life Sciences Keywords: Culicoides spp.; Zoo; deer diseases; hemorrhagic diseases

Online: 4 December 2023 (06:56:18 CET)

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Studies related to Orbivirus and its vectors were carried out at the Belo Horizonte Municipal Parks and Zoobotany Foundation (FPMZB-BH), Minas Gerais, Brazil where clinical case of Orbiviruses occurred in a female Brow brocket (Subulo gouazoubira) that died from an EHDV infection in 2020. From December 9, 2021, to November 18, 2022, collections of Culicoides sp. were performed at the FPMZB-BH. A higher prevalence of these insects was identified in the summer months, especially in February. It was identified that higher temperatures, humidity and accumulation of feces, as well as proximity to large animals such as camels and elephants, may be related to a higher capture of Culicoides. Culicoides of the guttatus group (Coquillett), 1904, Culicoides venezuelensis Ortíz & Mirsa, 1950, Culicoides debilipalpis Lutz, 1913, Culicoides foxi Ortíz, 1950, Culicoides of the Limai group, Culicoides pusillus Lutz, 1913, Culicoides paraensis (Goeldi), 1905 and Culicoides insignis Lutz, 1913, were identified. The species C. insignis and C. pusillus are vectors described as competent for Orbivirus transmission. The first species consisted of 75% of the collected midges and the second 6%. Furthermore, a species not yet reported in the state of Minas Gerais was identified, C. debilipalpis, also suspected of being a transmitter of these Orbiviruses. The feeding preference of some species of Culicoides was analyzed and it was demonstrated that C. insignis feeds on deer, Red deer (Cervus elaphus) and European fallow deer (Dama dama). Different species of Culicoides spp. were also identified feeding on humans, raising concerns about the likelihood of transmission of arboviruses at the site. Also, serum samples collected from 2012 to 2022 were received. A total of 72 serums from 14 species were tested and of these, 75% were seropositive for Bluetongue Virus (BTV) and 19% for Epizootic Hemorrhagic Disease Virus (EHDV), all originating from host species susceptible to BTV and EHDV infection, including several species of Cervids. After testing, variations in the presence of antibodies against BTV, a tapir and a fallow deer, and EHDV, a gemsbok, were identified in the sera tested in different years. These studies confirm the presence of BTV and EHDV vectors, as well as the potential circulation of these viruses in the zoo. Therefore, it is necessary to implement control measures to prevent species susceptible to Orbiviruses from becoming infected and developing clinical disease.

Preprint ARTICLE | doi:10.20944/preprints202312.0154.v1

Unlocking the Health Potential of Onobrychis cornuta and Veratrum lobelianum Extracts: Insights into MAPK Modulation, Germline Development, and Antitumor Properties in C. elegans: Implications for MAPK Modulation, Germline Development, and Antitumor Properties

Qinghao Meng, Nishit Pathak, Xiaojing Ren, Robert P. Borris, Hyun-Min Kim

Subject: Food Science And Technology, Biology And Life Sciences Keywords: herbal extracts; O. cornuta; V. lobelianum; DNA repair; meiosis; linoleic acid; germline development; medicinal plants

Online: 4 December 2023 (06:54:57 CET)

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Preprint ARTICLE | doi:10.20944/preprints202312.0144.v1

Redefining Textual Dynamics for Enhanced Text Style Transfer

Carlos Asanka, Conti Vatsalan, Rodolfo Patel

Subject: Artificial Intelligence And Machine Learning, Computer Science And Mathematics Keywords: Syntax-Aware Text Transformation; ; Style Classifier Analysis

Online: 4 December 2023 (06:53:06 CET)

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Preprint ARTICLE | doi:10.20944/preprints202312.0151.v1

Structural Analyses of Apricot Pectin Polysaccharides by NMR Spectroscopy

Zayniddin Kamarovich Muhidinov, Matlub H. Rahmonov, Abduvaly Jonmurodov, Jamshed Bobokalonov, Lin Shu Liu, Gary Strahan

Subject: Biomaterials, Chemistry And Materials Science Keywords: apricot pectin; NMR spectroscopy; RG-I; HG; RG-II; arabinogalactan; molecular weight; conformation

Online: 4 December 2023 (06:51:18 CET)

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The fine structure of Apricot pectin polysaccharides is discussed from both literature and recent work we have performed. Structural characterization utilized 1D and 2D homo- and hetero-nuclear NMR spectroscopy including results from High Performance Size Exclusion Chromatography (HP-SEC), HP Anion-Exchange Chromatography with Pulsed Amperometric Detection (HPAEC-PAD) and FTIR spectroscopy. The purified pectin fraction (F1AP) was found to be composed of D-galacturonic acid, L-rhamnose, D-arabinose and D-galactose in a 1.0 : 0.1 : 0.36 : 0.12 molar ratio, respectively, which is consistent with a pectin RG-1 branched with arabinogalactan side chain polysaccharides, and has a weight-average molecular weight of approximately 1588.2 kDa. The slope of the hydrodynamic radius versus the molar mass was 0.57, indicating the presence of coil conformations. The results from HPAEC-PAD, HPSEC and NMR spectroscopy (1H, 13C, zTOCSY, HSQC, HSQCTOXY and HMBC) demonstrated that F1AP fine fraction F1AP1, derived from original F1AP, has a backbone of (1→4)-linked -D-galacturonic acid and -L-rhamnopyranosyl residues branched with arabinogalactan of multiply glycosidic linkages of T- α-Araf, 3-α-Araf, 5-α-Araf, T- α -Arap, 2- α-Arap side chains, having methyl and acetylated groups, and has high molecular weights (1945 kDa). While the other F1A6 fraction consists predominately of an HG region of pectin polysaccharides with low molecular weights (117.5 kDa), less aggregated. The F1AP1 polysaccharide was highly viscous and its hydrodynamic radius was 64,3 nm. The exponent b of Rh-Mw (conformation plot) was determined to be 0.48, indicating a compact flexible coil conformation of the macromolecule in solution. However, the F1AP6 fraction of apricot fruits belong to backbone of repeats units of [-(1→4)-α-D-GalpA-1]n – both HG and partly contents RG-II polysaccharides, bearing heterosugar sidechains, including α-Ara, α -Rha and β-Gal residues and adopt more stiffness rod like conformation.

Preprint ARTICLE | doi:10.20944/preprints202312.0147.v1

Cardiometabolic Morbidity (Hypertension and Obesity) in PTSD: Treatment Implications for the Predictive Validity of Two Structures of the Impact of Event Scale-Revised

Amira Mohammed Ali, Saeed A. Al-Dossary, Carlos Laranjeira, Maha Atout, Haitham Khatatbeh, Abeer Selim, Abdulmajeed A. Alkhamees, Musheer A. Aljaberi, Annamária Pakai, Tariq Al-Dwaikat

Subject: Public Health And Health Services, Public Health And Healthcare Keywords: Impact of Event Scale-Revised/IES-R; cutoff score/cutoff point; three factors/six factors/dimensions; receiver operator curve (ROC); cardiometabolic* /hypertension; obesity/ high body mass index; dental healthcare workers

Online: 4 December 2023 (06:49:44 CET)

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Posttraumatic stress disorder (PTSD) and/or specific PTSD symptoms may evoke disordered eating and unhealthy lifestyles, resulting in adverse cardiometabolic events (e.g., hypertension and obesity) in certain groups, which may implicate the treatment of this complex condition. The diagnostic criteria of PTSD have lately expanded beyond the three common symptoms (intrusion, avoidance, and hyperarousal). Simultaneously, four-, five-, and six-dimensional structures of the Impact of Event Scale-Revised (IES-R), a popular PTSD measure, seem to be more robust than the original three-dimension structure. Within the context of COVID-19, this instrumental study used a convenience sample of 58 dental healthcare workers (HCWs) from Russia (mean age = 44.1±12.2 years, 82.8% females) to examine the criterion and predictive validity of two IES-R structures: the IES-R3 and the IES-R6 (with the added symptoms of numbing, sleep disturbance, and irritability). The subscales of the two IES-R structures expressed good internal consistency, strong correlations with the PTSD Symptom Scale (PSS), hypertension diagnosis, and high body mass index (BMI). In receiver-operating characteristic (ROC) curve analysis, all IES-R models perfectly predicted the PSS (all area under the curve (AUC) >0.9, p values <0.001). The IES-R, both hyperarousal subscales, and the IES-R3 intrusion subscale significantly predicted high BMI. Both avoidance subscales and the IES-R3 intrusion subscale, not the IES-R, significantly predicted hypertension. In conclusion, both IES-R structures can reliably measure PTSD symptoms. The IES-R, hyperarousal, and intrusion may be credible criterion variables for predicting high BMI within PTSD while the intrusion and avoidance subscales may reflect the cardiovascular consequences associated with PTSD more reliably than the IES-R itself. The IES-R subscales may predict cardiometabolic adversities in PTSD, signifying a need for proper assessment of lifestyle and the application of dietary and exercise interventions in order to lower physical morbidity in PTSD. Replicating the study in larger samples, which comprise different physical and mental conditions from heterogenous cultural contexts is pivotal to validate the results (e.g., in specific groups such as those with confirmed traumatic exposure and comorbid mood dysfunction).

Preprint ARTICLE | doi:10.20944/preprints202312.0146.v1

Spatial Identification and Hotspots of Ecological Risk from Heavy Metals in Urban Dust in the City of Cartagena, Se Spain.

Pura Marín-Sanleandro, María José Delgado-Iniesta, Anthony Felipe Sáenz-Segovia, Antonio Sánchez-Navarro

Subject: Environmental Science, Environmental And Earth Sciences Keywords: heavy metals; pollution; urban dust; Ecological Risk Index; traffic intensity; hostspots

Online: 4 December 2023 (06:48:37 CET)

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Preprint ARTICLE | doi:10.20944/preprints202312.0152.v1

Formulating a Community-Centric Indicator Framework to Quantify One Health Drivers of Antibiotic Resistance: A Preliminary Step towards Fostering ‘Antibiotic-Smart Communities’

Philip Mathew, Sujith J Chandy, Satya Sivaraman, Jaya Ranjalkar, Hyfa Mohammed Ali, Raghini Ranganathan, Shruthi Anna Thomas

Subject: Public, Environmental And Occupational Health, Public Health And Healthcare Keywords: ; Antibiotic Smart Communities; Indicator framework; WASH; IPC; One Health; ASC

Online: 4 December 2023 (06:46:17 CET)

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Preprint REVIEW | doi:10.20944/preprints202312.0139.v1

Topology of Saliva

Arturo Tozzi, James Peters

Subject: Biophysics, Biology And Life Sciences Keywords: Antipodal cells, Collective behavior; topological distance; flow; Borsuk– Ulam theorem. ; ;

Online: 4 December 2023 (04:42:09 CET)

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Preprint SHORT NOTE | doi:10.20944/preprints202312.0137.v1

Soils of the Prinevskaya Lowland and Prospects for Their Use

Ekaterina Chebykina, Evgeny Abakumov

Subject: Soil Science, Environmental And Earth Sciences Keywords: Prinevskaya lowland; fallow soils; agriculture

Online: 4 December 2023 (04:38:51 CET)

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Preprint ARTICLE | doi:10.20944/preprints202312.0125.v1

Computational Improvements of Enzyme Efficiency k_cat/K_M by Increasing Noise and Dissipation

Davor Juretić, Željana Bonačić Lošić

Subject: Biophysics, Biology And Life Sciences Keywords: enzyme efficiency; entropy production; noise; evolution; catalytic cycle

Online: 4 December 2023 (04:29:58 CET)

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Preprint ARTICLE | doi:10.20944/preprints202310.0720.v2

Enrollment, Engagement, and Effectiveness of a Large-Scale Diabetes Prevention Program Using Synchronous Distance Technology

Casey Collins, Erin McCallum, Kelly Nordby, Surabhi Aggarwal, Emily Griffith, Cathy Thomas, Carolyn Dunn

Subject: Public Health And Health Services, Public Health And Healthcare Keywords: prediabetes; National DPP; synchronous distance technology; distance learning delivery mode; lifestyle change program; Diabetes Prevention Recognition Program (DPRP)

Online: 4 December 2023 (04:29:50 CET)

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Preprint CASE REPORT | doi:10.20944/preprints202312.0123.v1

Delusional Misidentification Syndrome in Parkinson’s Dementia Resolved with Rivastigmine

Emile d'Angremont, Johan Berghuis, Iris Sommer

Subject: Neuroscience And Neurology, Medicine And Pharmacology Keywords: Capgras syndrome; Delusions; Parkinson disease; Dementia; Cholinesterase Inhibitors

Online: 4 December 2023 (04:27:03 CET)

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Preprint ARTICLE | doi:10.20944/preprints202312.0113.v1

Vehicle PEPS System with Intelligent Internet of Things

Ray-I Chang, Tzu-Chieh Lin, Jeng-Wei Lin

Subject: Artificial Intelligence And Machine Learning, Computer Science And Mathematics Keywords: Passive Entry Passive Start; Smart Watch; Electrocardiogram; Long Short-Term Memory; Auto Encoder; Collective Decision

Online: 4 December 2023 (04:26:06 CET)

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Preprint REVIEW | doi:10.20944/preprints202312.0106.v1

Risk Factors and Environmental Preventive Actions for Aspergillosis in Patients with Hematological Malignancies

Daniel Raposo Puglia, José Ángel Raposo Puglia, Emilio García-Cabrera, Fátima Morales, Juan Carlos Camacho-Vega, Angel Vilches-Arenas

Subject: Public, Environmental And Occupational Health, Public Health And Healthcare Keywords: Risk factors; Neutropenia; Primary prevention; Environmental control; Aspergillosis

Online: 4 December 2023 (04:25:15 CET)

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Background Aspergillus spp. is a widely distributed filamentous fungus in the environment due to its high sporulation capacity. Currently, invasive aspergillosis (IA) is the most common invasive fungal infection in patients with hematologic malignancies with high rates of mortality and morbidity. The multifactorial nature of the disease requires appropriate risk stratification to allow the most appropriate preventive measures to be adapted and implemented according to the characteristics of the patient. In this sense, the present research aims to identify recent risk factors and environmental control measures against invasive aspergillosis to establish preventive actions to reduce the incidence of invasive aspergillosis in hospitals; (2) Methods: We conducted a qualitative systematic review of the scientific literature on environmental risk factors and preventive measures for invasive aspergillosis in patients with hematological malignancies. The Medline, Cochrane and Scopus databases were consulted, following the PRISMA and STROBE guidelines; (3) Results Adequate implementation of environmental control measures is presented as the most efficient intervention in terms of prevention to decrease the incidence of invasive aspergillosis in hospitals. We identify neutropenia, fungal contamination, lack of adequate environmental control measures in hospitals and patients´ homes, duration of hospitalization, and anemia as independent risk factors. We show that HEPA, LAF and Plasmair® systems are suitable methods to reduce the concentration of airborne fungal spores. Antifungal prophylaxis did not influence the reduction of IA significantly in our study; (4) Conclusions: Proper professional training and environmental control measures in hospitals are essential for the prevention of invasive aspergillosis. We should optimize risk stratification for patients with hematologic malignancies. Antifungal prophylaxis should be complementary to environmental control measures and should never be substituted for these last ones. Studies should also be done to evaluate the efficiency of environmental control measures against IA at patients' homes.

Preprint ARTICLE | doi:10.20944/preprints202312.0119.v1

Fast Synthesis of Fine Boron Carbide Powders using Electromagnetic Induction Synthesis Method

Anna V. Gubarevich, Katsumi Yoshida

Subject: Materials Science And Technology, Chemistry And Materials Science Keywords: boron carbide; powders; electromagnetic induction; synthesis; oxidation resistance

Online: 4 December 2023 (04:22:45 CET)

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Preprint COMMUNICATION | doi:10.20944/preprints202312.0107.v1

First Record of Nemorilla floralis (Fallén 1810) (Diptera, Tachinidae) Parasitism on Box Tree Moth – Cydalima perspectalis (Walker 1859) (Lepidoptera, Crambidae) Larvae

Mario Bjeliš, Ana Romana Armanda, Hannah Nadel, Chris Raper, Gregory Simmons

Subject: Agricultural Science And Agronomy, Biology And Life Sciences Keywords: Buxus; invasive pest; parasitism rate; Croatia

Online: 4 December 2023 (04:21:37 CET)

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Preprint ARTICLE | doi:10.20944/preprints202310.1719.v2

Demographic Characteristics of Pre-Vaccinated Asymptomatic and Symptomatic SARS-CoV-2 Cases in Barwon South West Victoria, Australia

Shinae C Tobin-Salzman, Darcie Cooper, Bridgette J McNamara, Eugene Athan, Catherine M Bennett

Subject: Public Health And Health Services, Public Health And Healthcare Keywords: SARS-CoV-2; asymptomatic; COVID-19; symptom profile; demographic; testing; ethnicity

Online: 4 December 2023 (04:21:35 CET)

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Preprint ARTICLE | doi:10.20944/preprints202312.0134.v1

Impact of Digitalization on Budgeting Functions: An Investigation into Contingency Theory Perspectives

Andrzej Piosik, Anna Karmańska

Subject: Accounting And Taxation, Business, Economics And Management Keywords: budgeting; digitalization; budgeting functions; company performance; management accounting

Online: 4 December 2023 (04:20:35 CET)

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Preprint ARTICLE | doi:10.20944/preprints202312.0112.v1

Finite Element Simulation of Branch Vibration Model Based on Discrete Elements

Haobo Jiao, Juming Luo, Aifei Tang, Chen Ma, Yaping Li, Lihong Wang, Chengsong Li

Subject: Bioengineering, Engineering Keywords: fruit tree model; linear sweep frequency; forest fruit harvesting; branch spectrum; fruit tree vibration simulation

Online: 4 December 2023 (04:19:30 CET)

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Preprint ARTICLE | doi:10.20944/preprints202312.0133.v1

Tangles with k Ropes and 2k Hands

Aashna Hari, Emma Li, Rachel Liu

Subject: Algebra And Number Theory, Computer Science And Mathematics Keywords: tangles; isomorphism; analogs of groups; matrices; group presentation

Online: 4 December 2023 (04:16:55 CET)

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Preprint ARTICLE | doi:10.20944/preprints202312.0110.v1

Body-Camera: Teacher Identity through Video Elicitation and Video Essay to Create Shared Heritages

Ángela Barrera-García, Dolores Álvarez-Rodríguez

Subject: Education, Social Sciences Keywords: Teacher identity; Video essay; Video elicitation; Shared heritage; Arts-based Research

Online: 4 December 2023 (04:16:33 CET)

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Preprint ARTICLE | doi:10.20944/preprints202312.0130.v1

A Real-time Comparative Study of Sliding Mode and State Feedback Control for the Centrifugal Motor Pump in an Ultraviolet Water Treatment System Using the Bond Graph Approach

Said Riahi, Naoufel Zitouni, Hsen Abidi, Abdelkader Mami

Subject: Control And Systems Engineering, Engineering Keywords: UV water treatment; photovoltaic source; discharge lamp; electronic ballast; motor pump; motor speed; sliding mode control; state feedback; experimental results; bond graph approach

Online: 4 December 2023 (04:16:02 CET)

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Preprint ARTICLE | doi:10.20944/preprints202312.0109.v1

A Hybrid Method for Calculating the Chemical Composition of Steel with the Required Hardness After Cooling from the Austenitizing Temperature

Jacek Trzaska, Wojciech Sitek

Subject: Materials Science And Technology, Chemistry And Materials Science Keywords: steel; artificial neural networks; genetic algorithm; optimization; materials by design; heat treatment; hardness

Online: 4 December 2023 (04:15:28 CET)

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Preprint ESSAY | doi:10.20944/preprints202312.0132.v1

Unraveling the Tapestry: Immune Imprinting Amidst a Spectrum of Challenges for modRNA COVID-19 Vaccines

Ronald palacios castrillo

Subject: Epidemiology And Infectious Diseases, Medicine And Pharmacology Keywords: modRNA vaccines; immunoló; gical imprinting; Covid-19; SARSCoV-2 virus

Online: 4 December 2023 (04:14:57 CET)

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Preprint ARTICLE | doi:10.20944/preprints202312.0115.v1

Three-Dimensional Cultures for Collecting CNS and PNS Glial Secreted Factors, Vesicles and Scaffolds Free of Animal Serum Components

Cinzia Cocola, Tasnim Mohamed, Eleonora Piscitelli, Paride Pelucchi, Edoardo Abeni, Ettore Mosca, Guiseppina De Petro, Giovanni Porta, James Kehler, Martin Götte, Ileana Zucchi, Valerio Magnaghi, Rolland Reinbold

Subject: Biology And Biotechnology, Biology And Life Sciences Keywords: glial cells; neurogenesis; vasculogenic mimicry; microchanneling; central nervous system; peripheral nervous system; 2D and 3D serum replacement culture; glycoconjugates; vesicles

Online: 4 December 2023 (04:14:33 CET)

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Preprint ARTICLE | doi:10.20944/preprints202312.0124.v1

Outpatient Embedded Palliative Care for Patients With Advanced Thoracic Malignancy: A High-Value Practice

Mary C. Boulanger, Margaret D. Krasne, Ethan K. Gough, Samantha Myers, Ilene S. Browner, Josephine L. Feliciano

Subject: Oncology And Oncogenics, Medicine And Pharmacology Keywords: palliative care; thoracic oncology; high-value care

Online: 4 December 2023 (03:54:29 CET)

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Preprint ARTICLE | doi:10.20944/preprints202312.0127.v1

A Link Between Cell Wall Biogenesis, Pathogenesis, and Vigor in Walnut Root and Trunk Diseases

Houston J. Saxe, Sriema L. Walawage, Bipin Balan, Charles A. Leslie, Patrick J. Brown, Gregory T. Browne, Daniel A. Kluepfel, Andreas M. Westphal, Abhaya M. Dandekar

Subject: Biology And Biotechnology, Biology And Life Sciences Keywords: walnut; hybrid rootstock; RNAseq; crown gall; Phytophthora root and crown rots; vigor; disease susceptibilit

Online: 4 December 2023 (03:52:42 CET)

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Preprint ARTICLE | doi:10.20944/preprints202312.0120.v1

Validation of a Severe Acute Respiratory Syndrome Coronavirus 2 Microneutralization Assay for Evaluation of Vaccine Immunogenicity

Stephanie Hamilton, Mingzhu Zhu, Shane Cloney Clark, Penny Mayes, Jen Fenner, Leah Cui, Rongman Cai, Raj Kalkeri, Louis F Fries, Melinda Pryor, Joyce Plested

Subject: Virology, Biology And Life Sciences Keywords: microneutralization; COVID-19; Omicron variant; wildtype; Live virus,; XBB.1.5; MN50; SARS CoV-2; variants of concern; BSL-3

Online: 4 December 2023 (03:43:14 CET)

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Preprint CONCEPT PAPER | doi:10.20944/preprints202312.0116.v1

Efficient Indexing of Meta-Data (Extracted From Educational Videos)

Shalika Kumbham, Abhijit Debnath

Subject: Artificial Intelligence And Machine Learning, Computer Science And Mathematics Keywords: image processing; keyframes; indexing; metadata

Online: 4 December 2023 (03:36:00 CET)

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Preprint ARTICLE | doi:10.20944/preprints202312.0114.v1

Dynamics of Fricke-Painlevé VI surfaces

Michel Planat, David Chester, Klee Irwin

Subject: Geometry And Topology, Computer Science And Mathematics Keywords: isomonodromic deformation; Painlev\'e VI; $SL(2,\mathbb{C})$ character variety, algebraic surfaces; DNA/RNA

Online: 4 December 2023 (03:27:06 CET)

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Preprint ARTICLE | doi:10.20944/preprints202312.0111.v1

New Polymorph of β-Cyclodextrin with a Higher Bioavailability

Askar K. Gatiatulin, Ilya S. Balakhontsev, Sofia M. Talashmanova, Marat A. Ziganshin, Valery V. Gorbatchuk

Subject: Materials Science And Technology, Chemistry And Materials Science Keywords: beta-cyclodextrin; polymorphism; bioavailability; polymorphic transition; dissolution rate

Online: 4 December 2023 (03:05:33 CET)

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Preprint ARTICLE | doi:10.20944/preprints202312.0108.v1

Managing the Intermittency of Wind Energy Generation in Greece

Theodoros Christodoulou, Nikolaos S. Thomaidis, Ioannis Pytharoulis, Stergios Kartsios

Subject: Other, Environmental And Earth Sciences Keywords: wind generation; portfolio theory; optimization; factor analysis

Online: 4 December 2023 (03:04:28 CET)

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Preprint ARTICLE | doi:10.20944/preprints202312.0105.v1

System-Level Assessment of Massive MIMO With RIS in C-RAN and IoT Networks in Sub-6 GHz, MM-Wave and THz Bands

João Pedro Pavia, Vasco Velez, Nuno Souto, M. Marques da Silva, Américo Correia

Subject: Telecommunications, Engineering Keywords: RIS; massive MIMO; system-level simulation; C-RAN; precoding; 5G and beyond 5G

Online: 4 December 2023 (02:52:33 CET)

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Preprint ARTICLE | doi:10.20944/preprints202312.0073.v1

Potential Lithium Sedimentary Deposits of the Land and Deep Oceans

V. Balaram, John S. Armstrong-Altrin, Riyaz M. Khan, B. Srinivasa Rao

Subject: Geochemistry And Petrology, Environmental And Earth Sciences Keywords: minerals; sedimentary basin; pegmatite; brine lakes; economic geology; lithium exploration

Online: 4 December 2023 (02:27:35 CET)

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Preprint REVIEW | doi:10.20944/preprints202312.0070.v1

Recent Advances in “pH and Redox Responsive Polymer-Nano- Composites for Cancer Therapy

Shivalingayya Gaddimath, Shivanand Payamalle, Keshavananda Prabhu CP, Jaehyun Hur

Subject: Medicinal Chemistry, Chemistry And Materials Science Keywords: cancer; biological thiols; stimuli responsive; cancer therapeutics

Online: 4 December 2023 (02:26:05 CET)

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In recent years, cancer therapy has witnessed significant advancements, with a focus on personalized and targeted treatment strategies. One promising approach involves the use of stimuli-responsive biomaterials for site-specific drug release. Among these biomaterials, pH, and redox-triggered polymer-nano composites have gained immense attention due to their ability to respond to the specific tumor microenvironment, enhancing therapeutic efficacy while reducing off-target effects. Cancer cells often exhibit anomalous biochemical properties, attributed to lower cytosolic pH (acidic) and elevated redox potential through the epitomized upregulation of undesired genes. Such biological process substantially imbalance the level ions (protons) and biological thiols glutathione (GHS) in the cytoplasm as well as in the subcellular organelles. Superfluous accumulation of ions and redox imbalance is associated with proliferation, invasion, and growth of tumor. Because of high surface area, deep tissue penetration capability, higher hydrophilicity, hydrophobic interior for drug/gene efficient loading, biocompatibility and site-specific targeting efficiency, functionalized polymer nanocomposites are superior to conventional small molecular materials. Paradoxically conventional methods of drug delivery aided therapeutics accompanied with inherent drug/genes are encapsulated in biocompatible carrier or suitable transfecting agents generally suffered with low bioavailability, uncontrolled drug release, low cellular penetration, cellular internalization, toxicity, and poor drug loading efficiency. To overcome these issues, recently various multifunctional nanomaterials were developed, based on synergistic stimuli responsive aided drug release in a specified cellular or subcellular system. High therapeutic efficacy, of nanoparticles (NPs) mainly associated with surface functionalization through biocompatible polymeric materials, site-specific targeting units accompanied with stimuli responsive components. Followed by therapeutically important drug or genetic materials were loaded into NPs either in covalent or non-covalent approach. Intriguingly, combined pH and redox dual stimuli based functional materials specially based on polymeric nanocomposites for cancer therapeutics scarcely reported. This article provides the recent progress in pH and redox-responsive polymer-nano composites for site-specific drug delivery in cancer therapy. It explores design principles, fabrication methods, mechanism of action, and prospects of these dual-stimuli responsive biomaterials.

Preprint CASE REPORT | doi:10.20944/preprints202312.0085.v1

Restructuring of the Environmental Impact Process (EIA) AFTER Brexit for Incompleteness

Robert Kempton

Subject: Environmental Science, Environmental And Earth Sciences Keywords: incompleteness; sustainability; legal services regulations; climate change; renewable energy; environmental impact assessment; advanced project management services (APMS)

Online: 4 December 2023 (02:16:23 CET)

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Preprint DATA DESCRIPTOR | doi:10.20944/preprints202312.0072.v1

NMR-Based Metabolomics of Non-Human Primate Ocular Tissues: A Dataset

Vadim V. Yanshole, Maxim V. Fomenko, Lyudmila V. Yanshole, Nataliya A. Osik, Elena Y. Radomskaya, Dmitry V. Bulgin, Yuri P. Tsentalovich

Subject: Biochemistry And Molecular Biology, Biology And Life Sciences Keywords: quantitative metabolomics; NMR spectroscopy; eye tissues; serum; animal models; monkeys

Online: 4 December 2023 (02:13:54 CET)

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Preprint ARTICLE | doi:10.20944/preprints202312.0093.v1

Analytical Experimentations with Midjourney Architectural Virtual Lab: Defining Some Major Current Limits in AI-generated Representations of Islamic Architectural Heritage

Ahmad Sukkar, Mohamed W. Fareed, Moohammed Wasim Yahia, Salem Buhashima Abdalla, Iman Ibrahim, Khaldoun Abdul Karim Senjab

Subject: Engineering, Architecture, Building And Construction Keywords: Islamic architecture; architectural visualization; intangible heritage; text-to-image generation

Online: 1 December 2023 (21:29:02 CET)

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Preprint REVIEW | doi:10.20944/preprints202312.0091.v1

Recent Records on Bacterial Opportunistic Infections via the Dietary Route

Franca Rossi, Serena Santonicola, Carmela Amadoro, Lucio Marino, Giampaolo Colavita

Subject: Biology And Life Sciences, Immunology And Microbiology Keywords: dietary route; bacteria; opportunistic pathogens; recent infection records; risk factors

Online: 1 December 2023 (21:26:27 CET)

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Preprint REVIEW | doi:10.20944/preprints202312.0098.v1

The Laboratory Diagnosis of Malaria: A Focus on the Diagnostic Assays in Non‐Endemic Areas

Adriana Calderaro, Giovanna Piccolo, Carlo Chezzi

Subject: Public Health And Healthcare, Public Health And Health Services Keywords: Plasmodium sp.; imported malaria; diagnosis; molecular methods; polymerase chain reaction; RTD; microscopy; flow cytometry

Online: 1 December 2023 (16:44:42 CET)

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Preprint ARTICLE | doi:10.20944/preprints202312.0096.v1

Innovative Production of Phosphoric Acid-Hydrolyzed Chitin Nanocrystals for Pickering Emulsion Stabilization

Xiaoxue Jia, Peihua Ma, Kim Shi-Yun Taylor, Yiyang He, Yimin Mao, And Qin Wang

Subject: Chemistry And Materials Science, Nanotechnology Keywords: Chitin nanocrystals; Phosphoric acid; Pickering emulsion; Emulsion stability; Microstructure; Rheological property

Online: 1 December 2023 (16:35:20 CET)

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Preprint REVIEW | doi:10.20944/preprints202312.0095.v1

Hematological Neoplasm with Eosinophilia

Rosario M Morales-Camacho, Teresa Caballero-Velázquez, Juan José Borrero, Ricardo Bernal, Concepción Prats-Martín

Subject: Medicine And Pharmacology, Hematology Keywords: Eosinophilia,; hematological neoplasm; myeloid/lymphoid neoplasm with eosinophilia; tyrosine kinase fusion genes; acute leukemia

Online: 1 December 2023 (16:34:12 CET)

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Preprint ARTICLE | doi:10.20944/preprints202312.0094.v1

Hybrid Maker Spaces and the Circular City: A Case Study of Leuven, Belgium

Ingrid Schroder, Reham Elwakil, Koen Steemers

Subject: Arts And Humanities, Architecture Keywords: maker spaces; circular cities; urban manufacturing; circular economy; case study; Leuven; Maakleerplek

Online: 1 December 2023 (16:33:15 CET)

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Preprint ARTICLE | doi:10.20944/preprints202312.0097.v1

Novel Nanostructured Pd/Co‐Alumina Materials for the Catalytic Oxidation of Atmospheric Pollutants

Eleni F. Iliopoulou, Eleni Pachatouridou, Angelos A. Lappas

Subject: Chemistry And Materials Science, Other Keywords: CO oxidation; Methanol oxidation; Spray impregnation; Core-shell; Cobalt oxide; Palladium

Online: 1 December 2023 (16:32:29 CET)

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Preprint ARTICLE | doi:10.20944/preprints202312.0092.v1

Data Augmentation for Regression Machine Learning Problems in High Dimensions

Clara Guilhaumon, Nicolas Hascoët, Francisco Chinesta, Marc Lavarde, Fatima Daim

Subject: Computer Science And Mathematics, Artificial Intelligence And Machine Learning Keywords: Active Learning; Design of experiments; Regression; s-PGD

Online: 1 December 2023 (15:04:37 CET)

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Preprint BRIEF REPORT | doi:10.20944/preprints202312.0089.v1

Allele Frequencies and the Probability of Identity for 18 STR Loci Generated via the Canine GenotypesTM Panel 2.1 Kit in Golden Retriever, Miniature Dachshund, and Shiba Inu Groups for Forensic Applications

Fubuki Kunita, Chihiro Udagawa, Takeshi Inagaki, Hideto Suzuki, Makoto Bonkobara, Toshinori Omi

Subject: Biology And Life Sciences, Animal Science, Veterinary Science And Zoology Keywords: dog DNA identification; STR; golden retriever; miniature dachshunds; shiba inus

Online: 1 December 2023 (13:37:35 CET)

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Preprint ARTICLE | doi:10.20944/preprints202312.0090.v1

Green Synthesis, Characterization and Antibacterial Activity of Gold and Copper Nanoparticles from Lannea discolor (Sond.) Engl

Unarine Rambau, Nndivhaleni Anox Masevhe, Nneka Augustina Akwu, Amidou Samie

Subject: Biology And Life Sciences, Plant Sciences Keywords: copper nanoparticles; gold nanoflowers; green nanoparticle synthesis; Lannea discolor; plant extracts

Online: 1 December 2023 (13:36:53 CET)

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Preprint ARTICLE | doi:10.20944/preprints202312.0082.v1

The Long Road from Religious and Ethical Traditions to Welfare of Invertebrates

Jennifer A. Mather

Subject: Biology And Life Sciences, Animal Science, Veterinary Science And Zoology Keywords: Invertebrates; welfare; ethics; religious values; moral standing; sentience

Online: 1 December 2023 (13:36:15 CET)

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Preprint ARTICLE | doi:10.20944/preprints202312.0084.v1

Synthesis and Characterization of Metal Oxide Nanoparticles Anchored Carbon as Hybrid Adsorbents for Effective Heavy Metals-Uptake from Wastewater

Abdullah G ALanazi, Mohamed A Habila, Zeid A ALOthman, Ahmed Yacine Badjah-Hadj-Ahmed

Subject: Chemistry And Materials Science, Applied Chemistry Keywords: hybrid materials; zinc oxide nanoparticles; carbon; iron (III) oxide nanoparticle; adsorption; ki-netic and equilibrium studies

Online: 1 December 2023 (13:35:24 CET)

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Preprint ARTICLE | doi:10.20944/preprints202312.0086.v1

Wood and Cable-Based Variable Tilt Stilt-Mounted Solar Photovoltaic Racking System

Uzair Jamil, Nicholas Vandewetering, Seyyed Ali Sadat, Joshua M. Pearce

Subject: Engineering, Energy And Fuel Technology Keywords: open source; racking; biomaterials; wood; photovoltaic; mechanical design; balance of systems; renewable energy; solar energy

Online: 1 December 2023 (13:34:18 CET)

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