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Preprint ARTICLE | doi:10.20944/preprints202311.1809.v1

Carbon Stock in Coastal Ecosystems of Tombolos of the White and Baltic Seas

Ilya Bagdasarov, Michail Tseits, Iuliia Kryukova, Kseniya Taskina, Anna Boibrik, Igor Alexandrovich Ilichev, Junxiang Cheng, Ligang Xu, Pavel Krasilnikov

Subject: Soil Science, Environmental And Earth Sciences Keywords: “blue carbon”; carbon sequestration; marsh; wetland; soil carbon stock; plant biomass carbon stock; Phragmites australis

Online: 28 November 2023 (10:32:05 CET)

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Preprint REVIEW | doi:10.20944/preprints202311.1798.v1

Protein Hydrolysates from Fisheries Processing Byproducts: Production, Characteristics, Food Applications and Challenges

Mehdi Nikoo, Joe M. Regenstein, Mehran Yasemi

Subject: Food Science And Technology, Biology And Life Sciences Keywords: marine protein hydrolysates; hydrolysis variables; structure-function relations; antioxidant activity

Online: 28 November 2023 (10:30:41 CET)

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Preprint ARTICLE | doi:10.20944/preprints202311.1760.v1

An Exquisite Control Strategy for Ultralight Power Generation System

Pingping Wen, Zengquan Yuan, Zhibao Yuan, Haiping Xu

Subject: Electrical And Electronic Engineering, Engineering Keywords: Ultralight power generation system; Load power mutation; Exquisite control strategy; Mismatching degree; High-quality electrical energy

Online: 28 November 2023 (10:30:40 CET)

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Preprint ARTICLE | doi:10.20944/preprints202311.1792.v1

Bubble Wrap-Like Carbon-Coated Rattle-Type Silica@silicon Nanoparticles by Surface-Protected Etching as Hybrid Anodes for Lithium–Ion Batteries

Angelica Francisco Martino, Jiyun Jeon, Hyun-Ho Park, Hochun Lee, Chang-Seop Lee

Subject: Nanotechnology, Chemistry And Materials Science Keywords: lithium–ion battery; silicon anode; carbon nanomaterials; silica coating; yolk–shell structure; surface protected etching; template method; polydopamine coating

Online: 28 November 2023 (10:27:06 CET)

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Preprint ARTICLE | doi:10.20944/preprints202311.1535.v2

Energy -Momentum Localization in Quantum Gravity

Stuart Marongwe

Subject: Theoretical Physics, Physical Sciences Keywords: Quantum Gravity; Energy-Momentum Localization; Dark Energy; Dark Matter; Gravitational Waves; Black Holes

Online: 28 November 2023 (10:26:48 CET)

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Preprint ARTICLE | doi:10.20944/preprints202311.1764.v1

Analysis of the Effectiveness of a Freight Transport Vehicle at High Speed in a Vacuum Tube (Hyperloop Transport System)

David S. Pellicer, Emilio Larrodé

Subject: Transportation Science And Technology, Engineering Keywords: Mathematical modeling; high-speed transport; freight transport; sustainable transport

Online: 28 November 2023 (10:26:05 CET)

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Preprint ARTICLE | doi:10.20944/preprints202311.1790.v1

Non-axisymmetric Bouncing Dynamics on a Moving Superhydrophobic Surface

Wenhao Wang, Wenlong Yu, Zhiyuan Yu, Shuo Chen, Damin Cao, Xiaohua Liu, Jiayi Zhao

Subject: Fluids And Plasmas Physics, Physical Sciences Keywords: superhydrophobic substrate; droplet impact; spreading dynamics; contact time

Online: 28 November 2023 (10:25:52 CET)

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Preprint ARTICLE | doi:10.20944/preprints202311.1804.v1

Tuberculosis Case Finding in Kulon Progo District, Yogyakarta, Indonesia: Passive Versus Active Case Finding Using Mobile Chest X-ray

John Silwanus Kaku, Riris Andono Ahmad, Stephanie Main, Dwi Oktofiana, Bintari Dwihardiani, Rina Triasih, Philipp Du Cros, Geoffrey Chan

Subject: Public Health And Health Services, Public Health And Healthcare Keywords: tuberculosis; active-case finding; mobile chest X-ray

Online: 28 November 2023 (10:25:24 CET)

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Preprint ARTICLE | doi:10.20944/preprints202311.1800.v1

Changes in the Incidence and Human Papillomavirus-Positive Portion of Oropharyngeal Squamous Cell Carcinoma in Hong Kong

Zigui Chen, Amy BW Chan, Lok Sang Kam, Man Hin Chan, Jason YK Chan, Wai Tung Lee, Chit Chow, Siaw S Boon, Chichao Xia, Brian M Lam, Suki Lam, Rita WY Ng, Wendy CS Ho Ho, Eddy WH Lam, Christopher KC Lai, Paul KS Chan

Subject: Oncology And Oncogenics, Medicine And Pharmacology Keywords: HPV; oropharyngeal cancer; tonsil cancer; head and neck cancers; OPSCC; Hong Kong; Chinese

Online: 28 November 2023 (10:24:58 CET)

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Preprint ARTICLE | doi:10.20944/preprints202311.1759.v1

Chemical Interaction between the Sr4Al6O12SO4 Ceramic Substrate and Al–Si Alloys

José Amparo Rodríguez-García, Carlos Adrián Calles-Arriaga, Ricardo Daniel López-García, José Adalberto Castillo-Robles, Enrique Rocha-Rangel

Subject: Other, Engineering Keywords: solid state reaction; static immersion; wettability; corrosion; aluminum alloys

Online: 28 November 2023 (10:24:42 CET)

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Preprint ARTICLE | doi:10.20944/preprints202311.1751.v1

Exploring the Potential of Bacterial Cellulose and Biosurfactant as Eco-Friendly Biosorbent for Pharmaceutical Contaminants

Nathália Roberta Cardoso Mendes Castanho, Nathane De Marco, Érika Leão Ajala Caetano, Patrícia Lius Melo Alves, Thaisa Borim Pickler, Natasha Lien de Almeida Ibanez, Angela Faustino Jozala, Denise Grotto

Subject: Biomaterials, Chemistry And Materials Science Keywords: Biosorption; Bacterial Cellulose; Biosurfactant; Hormones; micropollutants; Drug

Online: 28 November 2023 (10:24:29 CET)

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Preprint ARTICLE | doi:10.20944/preprints202311.1802.v1

Role of Traditional Healers (Asing’anga) in the Preservation of Indigenous Medical Knowledge (IMK)

Dalitso Mvula

Subject: Ethnic And Cultural Studies, Social Sciences Keywords: indigenous knowledge; indigenous medical knowledge; asing’ anga; preservation ; ;

Online: 28 November 2023 (10:24:12 CET)

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Preprint ARTICLE | doi:10.20944/preprints202311.1796.v1

Exploratory Dividend Optimization with Entropy Regularization

Sang Hu, Zihan Zhou

Subject: Finance, Business, Economics And Management Keywords: Dividend optimization; entropy regularization; distributional control; exploratory HJB

Online: 28 November 2023 (10:23:46 CET)

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Preprint ARTICLE | doi:10.20944/preprints202311.1807.v1

Black Soldier Meal in Feed Could Adversely Affect Organic Broiler Meat Quality When Used for the Total or Half Replacement of Diet Proteins

Maria Chiara La Mantia, Massimo Calì, Luigi Petrocchi Jasinski, Michela Contò, David Meo Zilio, Monica Guarino Amato

Subject: Animal Science, Veterinary Science And Zoology, Biology And Life Sciences Keywords: organic broiler; protein feed; insect meal; lauric acid; meat quality; nutritional indices

Online: 28 November 2023 (10:23:35 CET)

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Preprint ARTICLE | doi:10.20944/preprints202311.1769.v1

HRA-Secure Proxy Re-encryption with Re-encryption Simulatability under Lwe in Standard Model

Bimei Wang, Li Hou, Lisha Yao, Feixiang Zhao, Jian Weng

Subject: Mathematics, Computer Science And Mathematics Keywords: Proxy re-encryption; re-encryption simulatability; honest re-encryption attacks; learning with errors; quantum-resistant

Online: 28 November 2023 (10:22:47 CET)

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Preprint ARTICLE | doi:10.20944/preprints202311.1785.v1

Utilizing Sentinel-2 for Recent Urbanization Trends on LULC Using a Semi-Automatic RF Classifier and Vegetation Change Dynamics for Gelephu, Bhutan

Karma Tempa, Masengo Ilunga, Abhishek Agarwal, And Tashi

Subject: Remote Sensing, Environmental And Earth Sciences Keywords: Sentinel-2; Semi-automatic classification; Random Forest; LULC; NDVI; Bhutan

Online: 28 November 2023 (10:22:30 CET)

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Preprint ARTICLE | doi:10.20944/preprints202311.1758.v1

Introduction of Deep Learning Based-IR Image Analysis for Marginal Reflex Distance-1 Measurement Method, Simultaneously Capture Images and Compute the Result: Clinical Validation Study

Bokeun Song, Hyeokjae Kwon, Sunje Kim, Yooseok Ha, Sang-Ha Oh, Seung-Han Song

Subject: Ophthalmology, Medicine And Pharmacology Keywords: Blepharoplasty; Deep learning; Machine learning; Eye movement measurements

Online: 28 November 2023 (10:19:49 CET)

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Preprint ARTICLE | doi:10.20944/preprints202311.1750.v1

Cultures of Human Skin Mast Cells, an Attractive In Vitro Model for Studies of Human Mast Cell Biology

Srinivas Akula, Shiva Raj Tripathi, Kristin Franke, Sara Wernersson, Magda Babina, Lars Hellman

Subject: Immunology And Microbiology, Biology And Life Sciences Keywords: mast cells; granule proteases; cathepsin G; tryptase; chymase; Fc receptors; IgE; prostaglandins; leukotrienes; heparin

Online: 28 November 2023 (10:18:36 CET)

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Studies of mast cell biology is dependent on relevant and validated in vitro models. We here present detailed information concerning the phenotype of both freshly isolated human skin mast cells (MCs), and of in vitro cultures of these cells that was obtained by analyzing their total transcriptome. Transcript levels of MC-related granule proteins and transcription factors were found to be remarkably stable over a 3-week culture period. Relatively modest changes were also seen for important cell surface receptors including the high affinity receptor for IgE, FCER1A, the low affinity receptor for IgG, FCGR2A, and the receptor for stem cell factor, KIT. FCGR2A was the only Fc receptor for IgG expressed by these cells. Comparisons of the present transcriptome against previously reported transcriptomes of mouse peritoneal MCs and mouse bone marrow derived MCs (BMMCs) revealed both similarities and major differences. Strikingly, cathepsin G was the most highly expressed granule protease in human skin MCs, in contrast to the almost total absent of this protease in both mouse MCs. Transcript levels for the majority of cell surface receptors were also very low compared to the granule proteases in both mouse and human MCs, with a difference of almost two orders of magnitude. An almost total absence of T cell granzymes was observed in human skin MCs, indicating that granzymes have no or only a minor role in human MC biology. Ex vivo skin MCs expressed high levels of selective immediate early genes and transcripts of heat-shock proteins. In validation experiments, we determined that this expression was an inherent property of the cells and not the result of the isolation process. Three to four weeks in culture results in an induction of cell growth related genes accompanying their expansion by 6-10-fold, which increases the number of cells for in vitro experiments. Collectively, we show that cultured human skin MCs resemble their ex vivo equivalents in many respects and are a more relevant in vitro model compared to mouse BMMCs for studies of MC biology, in particular human MC biology.

Preprint ARTICLE | doi:10.20944/preprints202311.1762.v1

Retain or Remove? Decision-Making Mechanism of Rural Industrial Park Redevelopment in Southern China

Zhuojun Liu, Hongjia Fang, Shanshan Xu, Yilin Wu, Keyin Wen, Zitong Shen, Hongmei Wang

Subject: Urban Studies And Planning, Social Sciences Keywords: rural industrial park; urban renewal; decision-making mechanism; cluster analysis; China

Online: 28 November 2023 (10:16:55 CET)

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Preprint ARTICLE | doi:10.20944/preprints202311.1742.v1

The Activity of the Dorsal Anterior Cingulate Cortex Promotes the Top–down Regulation of Sensorimotor Synchronization

Maho Uemura, Yoshitada Katagiri, Emiko Imai, Tomoko Ichinose, Katsuhiko Kondo, Hisatomo Kowa

Subject: Neuroscience And Neurology, Biology And Life Sciences Keywords: synchronization; modal completion; dACC; consistency

Online: 28 November 2023 (10:16:41 CET)

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Preprint ARTICLE | doi:10.20944/preprints202311.1739.v1

Supporting Social Goal Achievement for More Sustainable Land Use Transport Policy and Planning

John Stanley, Wai Yan Leong, Yan Hui Goh

Subject: Urban Studies And Planning, Social Sciences Keywords: cost benefit analysis; evaluation; land use transport planning; monetization; social exclusion; social goal

Online: 28 November 2023 (10:15:52 CET)

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The meaning of a good social outcome in land use transport policy/planning has been relatively underdeveloped, compared to economic and environmental sustainability goals, but this is now changing. Cities are increasingly prioritizing reducing social exclusion, with the allied intent of providing all residents with equitable access to the benefits of their city. However, in jurisdictions that use cost-benefit analysis to guide government decision-making, this poses a challenge: monetization of the benefits of reducing social exclusion is poorly developed. An evaluation gap thus confronts benefit-cost based assessment of initiatives intended to reduce social exclusion, compared to initiatives directed towards societal economic and environmental goals. This is a particular problem for public transport services that primarily enable people at risk of mobility-related social exclusion to access more opportunities in their society (social transit). The benefits of reducing social exclusion associated with these services have not been monetized, so social transit initiatives are poorly placed to argue their merits against competing initiatives where benefit monetization is more advanced (e.g., mass public transport and roads). The paper summarizes Australian research that has developed monetized measures for the value of increased trip making, bridging/bonding social capital, sense of community and several conceptions of wellbeing, and of reducing neighbourhood disadvantage, as these contribute to reducing social exclusion. New Singaporean research on the value of trip making to support reduced exclusion is also presented, affirming the Australian trip values. Trip values are then used in case study examples to show they can make a material difference to the societal worth of initiatives intended to reduce exclusion. Using these trip values, and other pathway values linked to reducing social exclusion, closes or at least substantially reduces the evaluation gap confronting social goal achievement in land use transport policy and planning, strengthening the case for reducing exclusion. These values will assist jurisdictions that are seeking to provide their residents with more equitable access to the benefits of their city.

Preprint REVIEW | doi:10.20944/preprints202311.1805.v1

Role of HDAC6 and HDAC6 Inhibition in Colorectal Cancer

Ana Vuletić, Katarina Mirjačić Martinović, Jelena Spasić

Subject: Cell And Developmental Biology, Biology And Life Sciences Keywords: HDAC6; histone deacetylases inhibitors; colorectal cancer

Online: 28 November 2023 (10:13:23 CET)

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Preprint ARTICLE | doi:10.20944/preprints202301.0023.v14

Bell's Theorem Begs the Question

Joy Christian

Subject: Quantum Science And Technology, Physical Sciences Keywords: Bell’ s theorem; local realism; Bell-CHSH inequalities; quantum correlations; Bell-test experimentsexperiments

Online: 28 November 2023 (10:12:21 CET)

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Preprint ARTICLE | doi:10.20944/preprints202311.1793.v1

Estimating the CSLE Biological Conservation Measures B Factor Using Google Earth Engine

Youfu Wu, Haijing Shi, Xihua Yang, Junfeng Shui, Minghang Guo, Li Li

Subject: Remote Sensing, Environmental And Earth Sciences Keywords: B-factor; CSLE; google earth engine; soil erosion; data patching

Online: 28 November 2023 (10:11:26 CET)

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Preprint ARTICLE | doi:10.20944/preprints202311.1794.v1

Ergodicity Breaking and Self-Destruction of Cancer Cells by Induced Genome Chaos

Sergey Shityakov, Viacheslav Kravtsov, Ekaterina V. Skorb, Michael Nosonovsky

Subject: Biochemistry And Molecular Biology, Biology And Life Sciences Keywords: cancer; ergodicity; BCL2; mutation rate; chromothripsis; rhabdomyosarcoma; genome chaos

Online: 28 November 2023 (10:09:44 CET)

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Preprint ARTICLE | doi:10.20944/preprints202311.1797.v1

Variability of Wood Basic Density and Other Parameters of Trees on a 45-Year-Old Plantation of Scots Pine (Pinus sylvestris L.)

Evgenii Sharapov, Yury Demakov, Aleksandr Korolev

Subject: Forestry, Biology And Life Sciences Keywords: core sample; drilling resistance; moisture content; nondestructive testing; initial plantation density; ultrasound velocity

Online: 28 November 2023 (10:08:30 CET)

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Preprint ARTICLE | doi:10.20944/preprints202311.1799.v1

Enhancement of the Antitumor and Antimetastatic Effect of Topotecan and Normalization of Blood Counts in Mice With Lewis Carcinoma by Tdp1 Inhibitors – New Usnic Acid Derivatives

Tatyana E. Kornienko, Arina A. Chepanova, Alexandra L. Zakharenko, Aleksandr S. Filimonov, Olga A. Luzina, Nadezhda S. Dyrkheeva, Valeriy P. Nikolin, Nelly A. Popova, Nariman F. Salakhutdinov, Olga I. Lavrik

Subject: Biochemistry And Molecular Biology, Biology And Life Sciences Keywords: usnic acid derivatives; TDP1 inhibitors; anticancer therapy; topotecan

Online: 28 November 2023 (10:06:47 CET)

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Preprint ARTICLE | doi:10.20944/preprints202311.1803.v1

Osteoprotective Effect of the Phytonutraceutical Ormona® on Post-Menopausal Osteoporosis in Wistar Rats

Aline Lopes Do Nascimento, Gabriel da Costa Furtado, Vinicius Maciel Vilhena, Helison de Oliveira Carvalho, Priscila Faimann Sales, Alessandra Ohana Nery Barcellos, Kaio Coutinho De Maria, Francinaldo Sarges Braga, Heitor Ribeiro Da Silva, Roberto Messias Bezerra, José Carlos Tavares Carvalho

Subject: Endocrinology And Metabolism, Medicine And Pharmacology Keywords: Isoflavones; Bone Density; Osteoporosis; Climacterium; Estrogen receptors.

Online: 28 November 2023 (10:02:32 CET)

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Preprint ARTICLE | doi:10.20944/preprints202311.1801.v1

Investigating Inter-Correlations Using Graph-Based Neural Networks in Aspect-Level Sentiment Analysis

Keohane Soukhanov, Fei Li, Woods Ali

Subject: Artificial Intelligence And Machine Learning, Computer Science And Mathematics Keywords: aspect-level sentiment analysis; sentiment interplay; graph-based neural networks; bidirectional attention

Online: 28 November 2023 (10:01:37 CET)

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In this paper, we present a groundbreaking methodology in the realm of aspect-level sentiment analysis, which capitalizes on the advanced capabilities of graph-based neural networks. Our approach, distinguished as the Aspect Correlation Graph Network (ACGN), represents a significant departure from conventional models. These traditional models often analyze aspects in isolation, failing to capture the intricate web of sentiment relationships that may exist within a single sentence. ACGN, however, is designed to address this gap by employing a sophisticated bidirectional attention mechanism, integrated with positional encoding. This unique combination not only enhances the model's ability to focus on relevant parts of the sentence but also aids in constructing detailed, aspect-focused representations. These representations are particularly crucial for understanding the nuanced interplay of sentiments associated with different aspects. Central to our model's architecture is the incorporation of a graph convolutional network. This network serves as a pivotal component in mapping and analyzing the complex network of sentiment correlations that can exist among various aspects within sentences. Through this integration, ACGN is able to unearth and interpret the subtle and often overlooked sentiment dynamics that traditional models might miss. Our comprehensive evaluations of the Aspect Correlation Graph Network, conducted using the SemEval 2014 datasets, have yielded promising results. These findings demonstrate a clear and significant advancement over the capabilities of existing models. Particularly, the results underscore the critical importance and utility of recognizing and understanding the connections between sentiments of different aspects in text analysis. This insight opens new avenues in the field of sentiment analysis, suggesting a broader application potential of ACGN in various contexts where understanding nuanced sentiment relationships is key. Overall, our study not only introduces a novel approach in aspect-level sentiment analysis but also sets a new standard for future research in this area. By highlighting the integral role of inter-aspect sentiment connections, ACGN paves the way for more sophisticated and accurate sentiment analysis tools, capable of handling the complexities of natural language with greater finesse and precision.

Preprint ARTICLE | doi:10.20944/preprints202311.1731.v1

Enhancing Performance and Promoting Sustainability in Female Handball: The Impact of Olympic Movement Training on Jumping, Throwing, Sprinting, and Change of Direction

Estela Orduña-Borraz, Elena Mainer-Pardos, Luis Alberto Marco-Contreras, Demetrio Lozano

Subject: Physical Therapy, Sports Therapy And Rehabilitation, Public Health And Healthcare Keywords: weightlifting; training; strength; power; team sports

Online: 28 November 2023 (09:25:00 CET)

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Preprint ARTICLE | doi:10.20944/preprints202311.1744.v1

High Hydrostatic Pressure Applied to Pre- and PostRigor Jack Mackerel (Trachurus murphyi) and the Assessment of Their Physicochemical Properties under Cold Storage

Liliana Zura-Bravo, Doina Solís, Klaudia Masztalerz, Gipsy Tabilo-Munizaga, Mario Pérez-Won, Roberto Lemus-Mondaca

Subject: Food Science And Technology, Biology And Life Sciences Keywords: Chilean jack mackerel; high hydrostatic pressure; rigor mortis; biochemical changes; cold storage; physicochemical properties.

Online: 28 November 2023 (09:23:58 CET)

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Preprint REVIEW | doi:10.20944/preprints202311.1728.v1

Application of Enzymes in Biomass Waste Management

Prangya Rath, Laxmi Kant Bhardwaj, Mini Chaturvedi, Abhishek Bhardwaj

Subject: Environmental Science, Environmental And Earth Sciences Keywords: Enzymes; Biomass; Waste Management; Waste Treatment; Microorganisms; Applications of Enzymes

Online: 28 November 2023 (09:23:07 CET)

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Preprint REVIEW | doi:10.20944/preprints202311.1770.v1

A Review of User Perceptions of Drought Indices and Indicators Used in the Diverse Climates of North America

Richard R. Heim Jr., Deborah J. Bathke, Barrie Bonsal, Ernest W. T. Cooper, Trevor Hadwen, Kevin Kodama, Dan McEvoy, Meredith Muth, John W. Nielsen-Gammon, Reynaldo Pascual Ramirez, Holly R. Prendeville, Brad Rippey, David B. Simeral, Richard L. Thoman Jr., Michael S. Timlin

Subject: Other, Environmental And Earth Sciences Keywords: user-inspired science; drought impacts; Canada; United States; Mexico; Pacific Islands; Caribbean Islands; user engagement; Kö; ppen climate zones; climate change; drought in tropical climates; drought in polar climates

Online: 28 November 2023 (09:09:54 CET)

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: Drought monitoring and early detection have improved greatly in recent decades through the development and refinement of numerous indices and indicators. However, a lack of guidance, based on user experience, exists as to which drought monitoring tools are most appropriate in a given location. This review paper summarizes the results of targeted user engagement and the published literature to improve the understanding of drought across North America, and to enhance the utility of drought monitoring tools. Workshops and surveys were used to assess and make general conclusions about the perceived performance of drought indicators, indices and impacts information used for monitoring drought in the five main Köppen climate types (Tropical, Temperate, Continental, Polar Tundra, Dry) found across Canada, Mexico, and the United States. In Tropical, humid Temperate, and southerly Continental climates, droughts are perceived to be more short-term (less than 6 months) in duration rather than long-term (more than 6 months). In Polar Tundra climates, Dry climates, Temperate climates with dry warm seasons, and northerly Continental climates, droughts are perceived to be more long-term than short-term. In general, agricultural and hydrological droughts were considered to be the most important drought types. Drought impacts related to agriculture, water supply, ecosystem, and human health were rated to be of greatest importance. Users identified the most effective indices and indicators for monitoring drought across North America to be the U.S. Drought Monitor (USDM) and Standardized Precipitation Index (SPI) (or another measure of precipitation anomaly), followed by the Normalized Difference Vegetation Index (NDVI) (or another satellite-observed vegetation index), temperature anomalies, crop status, soil moisture, streamflow, reservoir storage, water use (demand), and reported drought impacts. Users also noted the importance of indices that measure evapotranspiration, evaporative demand, and snow water content. Drought indices and indicators were generally thought to perform equally well across seasons in Tropical and the colder Continental climates, but their performance was perceived to vary seasonally in Dry, Temperate, Polar Tundra, and the warmer Continental climates, with improved performance during warm and wet times of the year. The drought indices and indicators, in general, were not perceived to perform equally well across geographies. This review paper provides guidance on when (time of year) and where (climate zone) the more popular drought indices and indicators should be used. The paper concludes by noting the importance of understanding how drought, its impacts, and indicators are changing over time as the climate warms, and by recommending ways to strengthen the use of indices and indicators in drought decision-making.

Preprint ARTICLE | doi:10.20944/preprints202311.1789.v1

Development of an Automatic Paddle Wheel Aerator and Re-mote Movement Water Quality Monitoring for Use in a Marine Shrimp Farm

Natee Thong-un, Piyathat Panthong, Hideharu Takahashi, Hiroshige Kikura, Wongsakorn Wongsaroj

Subject: Control And Systems Engineering, Engineering Keywords: internet of things (IoT); paddle wheel aerator; shrimp; water quality measurement; wireless sensor

Online: 28 November 2023 (08:27:08 CET)

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Preprint COMMUNICATION | doi:10.20944/preprints202311.1791.v1

Early Results of the Sandwich Technique Using Cyanoacrylate Glue and Polidocanol Foam Sclerotherapy for the Treatment of Varicose Veins

Marian Simka, Marcin Skuła

Subject: Cardiac And Cardiovascular Systems, Medicine And Pharmacology Keywords: cyanoacrylate glue; foam sclerotherapy; varicose veins

Online: 28 November 2023 (08:25:47 CET)

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Preprint ARTICLE | doi:10.20944/preprints202311.1786.v1

Assessing the Impact of Saw Chain Type and Wood Species on Wood Dust Concentration in Forestry Operations: Implications for Air Pollution in Urban and Industrial Areas

Vasiliki Dimou, Theodora Tioutiountzi, Kyriaki Kitikidou

Subject: Environmental Science, Environmental And Earth Sciences Keywords: chainsaw chain type; inhalable wood dust concentration; motor-manual harvesting; operator health and safety; tree species

Online: 28 November 2023 (08:24:19 CET)

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Preprint ARTICLE | doi:10.20944/preprints202311.1787.v1

MrisNet: Robust Ship Instance Segmentation in Challenging Marine Radar Environments

Feng Ma, Zhe Kang, Chen Chen, Jie Sun, Jizhu Deng

Subject: Marine Engineering, Engineering Keywords: ship segmentation; radar image; lightweight convolution; adaptive attention mechanism; loss function

Online: 28 November 2023 (08:22:28 CET)

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In high-traffic harbor waters, marine radar frequently encounters signal interference stemming from various obstructive elements, thereby presenting formidable obstacles in the precise identification of ships. To achieve precise pixel-level ship identification in the complex environments, a customized neural network-based ship segmentation algorithm named MrisNet is proposed. MrisNet employs a lightweight and efficient FasterYOLO network to extract features from radar images at different levels, capturing fine-grained edge information and deep semantic features of ship pixels. To address the limitation of deep features in the backbone network lacking detailed shape and structured information, an adaptive attention mechanism is introduced after the FasterYOLO network to enhance crucial ship features. To fully utilize the multi-dimensional feature outputs, MrisNet incorporates a Transformer structure to reconstruct the PANet feature fusion network, allowing for the fusion of contextual information and capturing more essential ship information and semantic correlations. In the prediction stage, MrisNet optimizes the target position loss using the EIoU function, enabling the algorithm to adapt to ship position deviations and size variations, thereby improving segmentation accuracy and convergence speed. Experimental results demonstrate that MrisNet achieves high recall and precision rates of 94.8% and 95.2%, respectively, in ship instance segmentation, outperforming various YOLO and other single-stage algorithms. Moreover, MrisNet has a model parameter size of 13.8M and real-time computational cost of 23.5G, demonstrating notable advantages in terms of convolutional efficiency. In conclusion, MrisNet accurately segments ships with different spot features and under diverse environmental conditions in marine radar images. It exhibits outstanding performance, particularly in extreme scenarios and challenging interference conditions, showcasing robustness and applicability.

Preprint ARTICLE | doi:10.20944/preprints202311.1788.v1

Discrimination/Classification of Edible Vegetable Oils From Raman Spatially Solved Fingerprints Obtained on a Portable Instrumentation

Guillermo Jiménez-Hernández, Fidel Ortega-Gavilán, M.Gracia Bagur-González, Antonio González-Casado

Subject: Analytical Chemistry, Chemistry And Materials Science Keywords: RAMAN fingerprints; edible vegetable oils; sunflower oil; olive oil; Patter recognition techniques; portable analyser; SORS

Online: 28 November 2023 (08:20:49 CET)

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Preprint ARTICLE | doi:10.20944/preprints202311.1720.v1

Exposure to Climate Change Information on Affect and Pro‐Environmental Behavioural Intentions: A Randomised Controlled Trial

Samantha Greaves, Caroline Harvey, Yashuhiro Kotera

Subject: Public, Environmental And Occupational Health, Public Health And Healthcare Keywords: climate change; positive and negative affect; pro-environmental behavioural intentions; climate anxiety

Online: 28 November 2023 (08:15:55 CET)

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Preprint ARTICLE | doi:10.20944/preprints202311.1784.v1

Modeling Autonomous Vehicle Responses to Novel Observations using Hierarchical Cognitive Representations Inspired Active Inference

Sheida Nozari, Ali Krayani, Lucio Marcenaro, David Martin Gomez, Carlo Regazzoni

Subject: Artificial Intelligence And Machine Learning, Computer Science And Mathematics Keywords: active inference; bayesian learning; imitation learning; action-oriented model; world model; autonomous driving

Online: 28 November 2023 (08:14:37 CET)

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Preprint ARTICLE | doi:10.20944/preprints202311.1709.v1

Continuous Reactive-Roll-to-Roll Growth of Carbon Nanotubes for Fog Water Harvesting Applications

Jean-Luc Meunier, Jeanne Ouellet, Kaustubh Basu, Alessio Afoujal, Richard Boudreault, Jason Robert Tavares

Subject: Nanotechnology, Chemistry And Materials Science Keywords: Carbon nanotubes; CNT; Continuous growth processing, Reactive-Roll-to-Roll synthesis (RR2R); Fog water harvesting; Hydrophillic-Hydrophobic surfaces; Chemical vapor deposition (CVD)

Online: 28 November 2023 (08:14:20 CET)

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Preprint REVIEW | doi:10.20944/preprints202311.1719.v1

Clinical and Genetic Features of Dravet Syndrome: A Prime Example of the Role of Precision Medicine in Genetic Epilepsy

Hueng-Chuen Fan, Ming-Tao Yang, Lung-Chang Lin, Kuo-Liang Chiang, Chuan-Mu Chen

Subject: Clinical Medicine, Medicine And Pharmacology Keywords: Dravet Syndrome; developmental epileptic encephalopathy; genetics; targeted therapy; epilepsy syndrome

Online: 28 November 2023 (08:12:09 CET)

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Preprint REVIEW | doi:10.20944/preprints202311.1711.v1

Extracellular Signal-Regulated Kinases: One Pathway, Multiple Fates

Xavier Deschênes-Simard, Mohan Malleshaiah, Gerardo Ferbeyre

Subject: Oncology And Oncogenics, Medicine And Pharmacology Keywords: cell proliferation; cell fate; ERK; senescence; cell signaling; EMT; apoptosis; pluripotency

Online: 28 November 2023 (08:10:31 CET)

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Preprint ARTICLE | doi:10.20944/preprints202311.1729.v1

Assessment of Diversity and Genetic Variability of Guava (Psidium guajava) by Means of Microsatellite Markers in Montería, Córdoba-Colombia

Enrique Pardo-Perez, Elizabeth Ramos-Rivero, Luis Causil-Vargas

Subject: Life Sciences, Biology And Life Sciences Keywords: genetic diversity; genetic variability; microsatellites; allele frequencies; population structure

Online: 28 November 2023 (08:08:48 CET)

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Preprint ARTICLE | doi:10.20944/preprints202311.1715.v1

Legal Interpretations of Persecution and Trauma: The U.S. Circuit Court of Appeals and Gender‐Based Asylum Claims

Connie Oxford

Subject: Gender And Sexuality Studies, Social Sciences Keywords: trauma; asylum; gender-based persecution; U.S. Circuit Court of Appeals

Online: 28 November 2023 (08:07:09 CET)

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Preprint ARTICLE | doi:10.20944/preprints202311.1710.v1

Sectoral Assessment of Energy, Water, Waste and Land Nexus in the Sustainability of Agricultural Products in Cameroon

Boris Abeli Pekarou Pemi, Donatien Njomo, René Tchinda, Jean Calvin Seutche, Armel Zambou Kenfack, Mahamat Hassane Babikir, Venant Sorel Chara-Dackou

Subject: Other, Environmental And Earth Sciences Keywords: Quantitative and qualitative analysis; Nexus Energy-Water-Waste-Land-agricultural products; sustainability; consumption and production; Cameroon

Online: 28 November 2023 (08:05:35 CET)

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Preprint ARTICLE | doi:10.20944/preprints202311.1725.v1

Comparative Assessment of NeRF and Photogrammetry in Digital Heritage: Impact of Varying Image Conditions on 3D Reconstruction

Valeria Croce, Dario Billi, Gabriella Caroti, Andrea Piemonte, Livio De Luca, Philippe Véron

Subject: Civil Engineering, Engineering Keywords: NeRF; Cultural Heritage; 3D reconstruction; photogrammetry; 3D surveying

Online: 28 November 2023 (08:04:31 CET)

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Preprint ARTICLE | doi:10.20944/preprints202311.1730.v1

Reapplication Potential of Historic Pb-Zn Slag in Regard to Net Zero Principles

Dragan Radulović, Anja Terzić, Jovica Stojanović, Vladimir Jovanović, Dejan Čedomir Todorović, Branislav Božidar Ivošević

Subject: Civil Engineering, Engineering Keywords: critical raw materials; alternative deposits; secondary resources; building materials; instrumental analyses; microscopy.

Online: 28 November 2023 (08:03:39 CET)

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Smelting used to be less efficient in the past, so wastes obtained from historical processing at smelter plants usually contain certain quantities of valuable metals. A case study was conducted, which included an investigation of the physicochemical, mineralogical, and microstructural properties of raw material found at the historic slag pond near the Topilnica Veles smelter in North Macedonia. The Pb-Zn slag was sampled using traditional geophysical methods such as drill holes and pitholes. The mineralogical and microstructural analysis revealed that the Pb-Zn slag is a very complex and inhomogeneous alternative raw material with utilizable levels of metals, specifically Pb (2.24 wt%), Zn (7.10 wt%), and Ag (27.53 ppm). Amorphous phase, lead alloys, zinc alloys, wurtzite, sphalerite, galena, cerussite, elemental silver, elemental copper, elemental iron, magnetite, spinel, rutile, hematite, and troilite were also identified through qualitative mineralogical analysis. The glassy matrix composed of spinel, silicates, and mixed spinel-silicate is the most abundant constituent in slag composition. The various potential applications of the slag are possible based on its mineralogical and geochemical properties. Because the extraction of Pb, Zn, and Ag has certain economic potential, the next step, which will include gravity concentration and magnetic separation procedures, will be to form metal concentrates into their collective concentrate, from which the maximum amount of silver can be extracted. Slag's amorphous spinel, silicate, and mixed spinel-silicate phases, which contain high concentrations of SiO2, Al2O3, CaO, and Fe2O3, are suitable for use in building materials such as cement clinker, filler, or aggregate for concrete or mortar. The goal of this research is to close the circle of slag's reutilization potential in terms of Net Zero and Zero Waste principles, so it is critical to thoroughly investigate the material and establish methods and preparation processes, as well as ways of concentrating useful components into commercial products.

Preprint REVIEW | doi:10.20944/preprints202311.1714.v1

Assessment of E‐Waste Pollution Level in Soil and Water and Its Impact on Human Health: A Review

Laxmi Kant Bhardwaj, Prangya Rath, Moharana choudhury

Subject: Environmental Science, Environmental And Earth Sciences Keywords: E-Waste; Soil; Water; Heavy metals; Human Health ;

Online: 28 November 2023 (08:03:33 CET)

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Preprint ARTICLE | doi:10.20944/preprints202311.1721.v1

Comparative Analysis of Telepresence Robots’ Video Performance: Evaluating Camera Capabilities for Remote Teaching and Learning

Aleksei Talisainen, Janika Leoste, Sirje Virkus

Subject: Robotics, Computer Science And Mathematics Keywords: Telepresence robot; telepresence; robotic telepresence; vision; vision acuity; education; optometry.

Online: 28 November 2023 (08:02:36 CET)

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Preprint ARTICLE | doi:10.20944/preprints202311.1783.v1

Associations Between Mitochondrial Content, Telomere Length, and mtDNA to nDNA Ratio in Human Sperm: Relevance to Reproductive Health

Efthalia Moustakli, Athanasios Zikopoulos, Charikleia Skentou, Sofoklis Stavros, Efstratios M. Kolibianakis, Peter Drakakis, Christos V. Chalitsios, Ioannis Georgiou, Athanasios Zachariou

Subject: Biochemistry And Molecular Biology, Biology And Life Sciences Keywords: telomere length; mitochondria; oxidation; body mass index; IVF/ICSI; male infertility

Online: 28 November 2023 (07:56:30 CET)

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Abstract: Important variables that affect the quality and functionality of sperm and may affect male reproductive health and fertility include telomere length, mitochondrial content, and the ratio of mitochondrial DNA (mtDNA) to nuclear DNA (nDNA). The purpose of this study was to look at the connections between these three sperm characteristics and how they might affect a woman's ability to conceive. Methods: Data were collected from 82 men who underwent IVF/ICSI at the University Hospital of Ioannina's IVF Unit in the Obstetrics and Gynecology Department. Evaluations included sperm morphology, sperm count, sperm motility, and participant history. To address this, males of reproductive age who were categorized into three body mass index (ΒΜΙ) groups—normal, overweight, and obese—had their sperm samples tested. Results: Our findings indicate a negative correlation between relative telomere length and ΒΜΙ for both the normal and overweight groups. Conversely, a positive correlation was observed for the obese group, indicating a possible relationship between mitochondrial health and telomere maintenance. The results were statistically significant only for the obese group. Furthermore, a negative correlation was observed between telomere length and mitochondrial content in both the normal and overweight groups, indicating that a lower mitochondrial content may be linked to longer telomeres. Nonetheless, there was a positive correlation for the group that was obese. For all three groups, the data did not reach statistical significance. Given that mitochondrial con-centration and telomere length are both markers of cellular integrity and health, these correla-tions may have an impact on the quality of sperm. Furthermore, the relative telomere length of the normal and overweight groups had a negative correlation with the ratio of mtDNA to nDNA, though the obese group showed a positive correlation. The findings were not statistical-ly significant in any of the groups under investigation. According to this, male fertility may be negatively impacted by an imbalance in the copy number of the mitochondrial genome com-pared to the nuclear DNA in sperm. Conclusions: Our research, in essence, emphasizes the interaction among human sperm telo-mere length, mitochondrial concentration, and the mtDNA to nDNA ratio. Gaining knowledge of these correlations could help explain the reasons behind male infertility and open up new treatment options for reproductive health problems. The functional importance of these correla-tions and possible uses in therapeutic contexts require more investigation.

Preprint ARTICLE | doi:10.20944/preprints202311.1782.v1

Efficiency of Micro and Small Wood-Processing Enterprises in the EU – Evidence From DEA and Fractional Regression Analysis

Nikolay Neykov, Mariana Sedliačiková, Petar Antov, Marek Potkány, Emil Kitchoukov, Aureliu-Florin Hălălișan, Natália Poláková

Subject: Economics, Business, Economics And Management Keywords: DEA; wood processing enterprises; small enterprises; fractional regression

Online: 28 November 2023 (07:49:48 CET)

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Preprint ARTICLE | doi:10.20944/preprints202311.1779.v1

Exact and Paraxial Broadband Airy Wave Packets in Free Space and a Temporally Dispersive Medium

Ioannis M. Besieris, Peeter Saari

Subject: Optics And Photonics, Physical Sciences Keywords: airy beams; nondiffracting pulses; localized waves; space-time wavepackets

Online: 28 November 2023 (07:31:50 CET)

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Preprint ARTICLE | doi:10.20944/preprints202311.1748.v1

Characterization of Inflammasomes and Their Regulation in the Red Fox

Huijeong Ahn, Dong-Hyuk Jeong, Gilyoung Lee, Suk-Jin Lee, Jeong-Jin Yang, Yo-Han Kim, Tae-Wook Hahn, Sooyoung Choi, Geun-Shik Lee

Subject: Animal Science, Veterinary Science And Zoology, Biology And Life Sciences Keywords: Red foxes; Vulpes vulpes; inflammasome; cytokine; interleukin-1beta

Online: 28 November 2023 (07:29:31 CET)

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Preprint ARTICLE | doi:10.20944/preprints202311.1753.v1

Power Transformers Fault Detection with Machine Learning: A Comparison of Classic and autoML Approaches

Guillermo Santamaría-Bonfil, G. Arroyo-Figueroa, M. Zuniga-Garcia, Carlos Gustavo Azcárraga Ramos, A. Bassam

Subject: Artificial Intelligence And Machine Learning, Computer Science And Mathematics Keywords: Transformers Fault Diagnosis; Machine Learning; Automatic Machine Learning; Power Systems

Online: 28 November 2023 (07:28:41 CET)

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Preprint ARTICLE | doi:10.20944/preprints202311.1755.v1

Anion Doping of Tungsten Oxide with Nitrogen: Reactive Magnetron Synthesis, Crystal Structure, Valence Composition, and Optical Properties

Insaf F. Malikov, Nikolay M. Lyadov, Myakzyum Kh. Salakhov, Lenar R. Tagirov

Subject: Applied Physics, Physical Sciences Keywords: electrochromism; tuhgsten trioxide; nitrogen doping; optical transmittance; spectroscopical ellipsometry

Online: 28 November 2023 (07:26:37 CET)

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Preprint COMMUNICATION | doi:10.20944/preprints202311.1741.v1

Plasmonic Fabry-Pérot Nanocavities Produced via Solution Methods

Stylianos Kioumourtzoglou, Robert Bericat Vadell, Vitor R. Silveira, Jacinto Sá

Subject: Chemical Physics, Physical Sciences Keywords: plasmonic nanomaterials; Fabry-Pé; rot nanocavity; bottom-up solution methods; opaque; semitransparent devices

Online: 28 November 2023 (07:25:24 CET)

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Preprint ARTICLE | doi:10.20944/preprints202311.1766.v1

Empowering Sentence Representation with Semantic-Enhanced Tree-LSTMs

Andrew H. Chris, Fei Lee, Woods Ali

Subject: Artificial Intelligence And Machine Learning, Computer Science And Mathematics Keywords: Natural Language Processing; Semantic Parsing; ; Syntactic Dependencies; ; Language Understanding

Online: 28 November 2023 (07:23:54 CET)

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Preprint ESSAY | doi:10.20944/preprints202311.1756.v1

Logics of Discovery III: What ‘Sleeps’ When We Are Dreaming? Dream Consciousness as Suspension of the ‘Will’ to Narratively Organise Our Experiences

Giovanni Stanghellini

Subject: Psychiatry And Mental Health, Medicine And Pharmacology Keywords: Co-production; dream consciousness; Guido Morselli; identity obsession; narrative obsession; now-vigilance; self

Online: 28 November 2023 (07:21:32 CET)

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Preprint REVIEW | doi:10.20944/preprints202311.1761.v1

How to Incorporate Cultural Values and Heritage in Maritime Spatial Planning (MSP): A Systematic Review

Eirini Aikaterini Barianaki, Stella Sofia Kyvelou, Dimitrios G. Ierapetritis

Subject: Geography, Planning And Development, Social Sciences Keywords: Maritime Spatial Planning; Coastal management; Socio-cultural values; Cultural Ecosystem Services; participatory approach; local communities

Online: 28 November 2023 (07:19:29 CET)

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Preprint ARTICLE | doi:10.20944/preprints202311.1738.v1

Assessment of Landslide Risk in the Jinbu Area, Korea: Integrating Spatial Models with High Resolution Social Economic Data

Al Mamun, Jang Dong-Ho

Subject: Geography, Environmental And Earth Sciences Keywords: Landslide; Spatial prediction; Vulnerability; Cross-validation; Prediction table; Landslide risk

Online: 28 November 2023 (07:18:26 CET)

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This research deals with risk assessment for human life, man-made infrastructure, and agriculture in a landslide-prone area using GIS-based spatial methods. The study area landslide inventory map was prepared based on previous landslide information, aerial photograph analysis, and several field observations. A total of 550 landslides have been included with 182 debris flow and 368 soil slides. All included landslides were classified into two groups by random selection; half were used for model calibration and the rest were used for cross-validation. In the analysis, fourteen causative factors were vastly used, such as aspect, slope, curvature, elevation, topographic wetness index, forest timber diameter, forest type, forest crown density, forest age, land-use, geology, soil drainage, soil depth, and soil texture. Moreover, to identify the interaction between occurred landslides and causative factors, the affected pixels were divided into different sub-classes using a frequency ratio method. Based on the total dataset, three landslide susceptibility maps were constructed using Bayesian prediction, likelihood ratio, and fuzzy set method. By evaluating cross-validation and success rate curve, model susceptibility results were plotted with a receiver operating characteristic (ROC) curve and the area under the curve (AUC) was estimated. In addition, for risk assessment, each social data layer such as agriculture, house, industry, business, road, river, population intensity, monetary value, and vulnerability level was added based on the local standard and incident time and was converted into US dollars. During the analysis, each method hazard map was used with a specific group of thematic data layers. Subsequently, for preparing the probability table, study area total pixels and predictive landslide affected pixels were considered. Matching with the affected pixels, a standard of 5000 pixels was selected to run the final evaluation. Based on the results, the agricultural field showed the highest vulnerability and estimated risk of US $ 16.3 million. Further, the man-made infrastructure map showed a risk of US $ 31.3 million. The total estimated population casualties were 6.77, which was relatively similar to the published data.

Preprint REVIEW | doi:10.20944/preprints202311.1733.v1

Omentin: An Atheroprotective Adipokine for Vascular Health

Cristina M Sena

Subject: Endocrinology And Metabolism, Medicine And Pharmacology Keywords: Omentin; adipokines; diabetes mellitus; endothelial dysfunction; inflammation; oxidative stress

Online: 28 November 2023 (07:16:38 CET)

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Preprint REVIEW | doi:10.20944/preprints202311.1752.v1

Wen Ting Tong, Ananta Seth, Mary PE Ng, Shao Chuen Tong, Amanda Lau, Tina YT Chen, Suan Ee Ong, Joanne SY Yoong

Subject: Public Health And Health Services, Public Health And Healthcare Keywords: vaccine uptake; immunisation; adults; older people; elderly; Asia-Pacific; barriers; facilitators; factors; interventions

Online: 28 November 2023 (07:15:38 CET)

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Preprint ARTICLE | doi:10.20944/preprints202311.1734.v1

An Efficient and Robust ILU(k) Preconditioner for Steady-State Neutron Diffusion Problem Based on MOOSE

Yingjie Wu, Han ZHANG, Lixun Liu, Huanran Tang, Qinrong Dou, Jiong Guo, Fu Li

Subject: Energy And Fuel Technology, Engineering Keywords: preconditioning; JFNK; coloring algorithm; reordering algorithm; incomplete LU factorization

Online: 28 November 2023 (07:14:29 CET)

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Preprint ARTICLE | doi:10.20944/preprints202311.1767.v1

Assessing the Impact of Genotype-by-Environment Interactions on Agronomic Traits in Elite Cowpea Lines Across Agro-ecologies in Nigeria

Bosede Olufunke Popoola, Patrick Obia Ongom, Saba B. Mohammed, Abou Togola, Daniel Jockson Ishaya, Garba Bala, Christian Fatokun, Ousmane Boukar

Subject: Agricultural Science And Agronomy, Biology And Life Sciences Keywords: Cowpea (Vigna unguiculata); G x E interactions; stability; GGE biplot

Online: 28 November 2023 (07:13:24 CET)

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Preprint ARTICLE | doi:10.20944/preprints202311.1735.v1

Explainable AI and Voting Ensemble Model to Predict the Results of Seafood Product Importation Inspections

Saksonita Khoeurn, Kyunghee Lee, Wan-Sup Cho

Subject: Artificial Intelligence And Machine Learning, Computer Science And Mathematics Keywords: border inspection; decision tree; ensemble learning; explainable artificial intelligence; \begin{document}

Online: 28 November 2023 (07:08:48 CET)

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Preprint ARTICLE | doi:10.20944/preprints202311.1732.v1

A Distance Based Two-Sample Test of Means Difference for Multivariate Datasets

Alexander Novoselsky, Eugene Kagan

Subject: Probability And Statistics, Computer Science And Mathematics Keywords: multivariate two-sample problem; multivariate means test; distance-based statistic; two-sample Kolmogorov-Smirnov test

Online: 28 November 2023 (07:07:47 CET)

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Preprint ARTICLE | doi:10.20944/preprints202311.1697.v1

Exploring the link between Mindful Eating, Instagram engagement and Eating Disorders: A focus on Orthorexia Nervosa

Efstratios Christodoulou, Verra Markopoulou, Antonios E Koutelidakis

Subject: Public Health And Health Services, Public Health And Healthcare Keywords: mindful eating; orthorexia nervosa; eating disorders; instagram; mental health; body image

Online: 28 November 2023 (06:59:37 CET)

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Preprint ARTICLE | doi:10.20944/preprints202311.1700.v1

Assessment of the One Health Status in Romania From the Livestock Farming Perspective

Claudia Terezia Socol, Cristina Maria Maerescu, Florin Leontin Criste, Florin Gheorghe Lup, Aurelia Ioana Chereji, Aurelia Coroian, Cristinel Gigi Șonea, Nastasia Belc, Daniel Mierliță

Subject: Agricultural Science And Agronomy, Biology And Life Sciences Keywords: farm animal genetic resources; sustainable livestock farming; local breed conservation; one health; global health

Online: 28 November 2023 (06:58:05 CET)

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Preprint REVIEW | doi:10.20944/preprints202311.1701.v1

Hydroxyapatite as a Material for Transplantology: Clinical Experience and Prospects of Application

Vitaliy Markelov, Kseniya Danilko, Vadim Solntzev, Svetlana Piatnitskaia, Olga Shangina, Azat Bilyalov, Svyatoslav Chugunov, Iskander Akhatov

Subject: Ceramics And Composites, Chemistry And Materials Science Keywords: hydroxyapatite; bone grafting; nanoparticles; immune response; mitochondria

Online: 28 November 2023 (06:56:44 CET)

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Preprint ARTICLE | doi:10.20944/preprints202311.1757.v1

FU-Serve: Fog-enabled UAV-as-a-Service for IoT Applications

Arijit Roy, Raju Imandi, Pavan Kumar B N

Subject: Artificial Intelligence And Machine Learning, Computer Science And Mathematics Keywords: Unmanned Aerial Vehicle (UAV); Fog computing; IoT; UAV virtualization; Genetic algorithm; Optimization

Online: 28 November 2023 (04:12:51 CET)

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Preprint ARTICLE | doi:10.20944/preprints202311.1747.v1

Assessing the Efficacy of Alumni Crowdfunding and Strategic Investments for Overcoming Funding Challenges in French Language Education

Udeh Vanessa Georgina

Subject: Literature And Literary Theory, Arts And Humanities Keywords: Efficacy; alumni crowdfunding; strategic investments; funding challenges; French language education

Online: 28 November 2023 (03:49:33 CET)

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Preprint ARTICLE | doi:10.20944/preprints202205.0015.v6

A Critical Analysis of the Quantum Nonlocality Problem: On the Polemic Assessment of What Bell Did

Justo Pastor Lambare

Subject: Quantum Science And Technology, Physical Sciences Keywords: Bell inequality; locality; nonlocality; local causality

Online: 28 November 2023 (03:47:09 CET)

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Preprint ARTICLE | doi:10.20944/preprints202311.1745.v1

Transcription Factor OsbZIP60-Like Regulating OsP5CS1 Gene and 2-Acetyl-1-Pyrroline (2-AP) Biosynthesis in Aromatic Rice

Gegen Bao, Umair Ashraf, Lin Li, Jingxuan Qiao, Chunling Wang, Yixiog Zheng

Subject: Agricultural Science And Agronomy, Biology And Life Sciences Keywords: Fragrant rice; 2-acetyl-1-pyrroline; OsP5CS1; OsbZIP60-like

Online: 28 November 2023 (03:45:25 CET)

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Preprint ARTICLE | doi:10.20944/preprints202311.1740.v1

Tocilizumab Exerts Anti-tumor Effects on Proliferation, Invasiveness, ERK 1/2 and STAT3 Signaling Transduction in Colorectal Carcinoma Cell Xenografts Corresponding to Expression Levels of IL-6 Receptors

Yuan-Chiang Chung, Szu-Jung Chen, Yuan-Chiang Chung, Wei-Chun Liu, Ming-Tsung Lai, Ting-Yu Kao, Wei-Shun Yang, Chien-Hui Yang, Chih-Ping Hsu, Jia-Feng Chang

Subject: Life Sciences, Biology And Life Sciences Keywords: Interleukin-6 receptor; colorectal carcinoma; xenograft; Tocilizumab; Ki-67; ERK 1/2; STAT3

Online: 28 November 2023 (03:43:13 CET)

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Preprint REVIEW | doi:10.20944/preprints202311.1746.v1

Construction Site Hazard Identification and Worker Adverse Reaction Monitoring Using Electroencephalograms: A Review

Boan Wei, Bin Yang, Weiling Zhang, Pengju Liu, Hanliang Fu, Zhihan Lv, Faming Wang

Subject: Civil Engineering, Engineering Keywords: EEG; Construction; hazard identification; Worker safety; Adverse reaction

Online: 28 November 2023 (03:41:11 CET)

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Preprint ARTICLE | doi:10.20944/preprints202311.1736.v1

Conducting and Magnetic Hybrid Polypyrrole/Nickel Composites and their Application in Magnetorheology

Marek Jurča, Jarmila Vilčáková, Natalia E. Kazantseva, Andrei Munteanu, Lenka Munteanu, Michal Sedlačík, Jaroslav Stejskal, Miroslava Trchová, Jan Prokeš

Subject: Materials Science And Technology, Chemistry And Materials Science Keywords: nickel microparticles; polypyrrole; hybrid composites; resistivity; conductivity; magnetization; magnetorheology

Online: 28 November 2023 (03:39:07 CET)

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Preprint ARTICLE | doi:10.20944/preprints202311.1737.v1

Small Doses of Lime with Common Fertilizer Practices Improve Soil Characteristics and Foster the Sustainability of Maize Production

Marijana Dugalić, Ljubomir Životić, Boško Gajić, Dragana Latković

Subject: Agricultural Science And Agronomy, Biology And Life Sciences Keywords: liming; mineral fertilizers; food security; acid soil; maize

Online: 28 November 2023 (03:37:07 CET)

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Preprint ARTICLE | doi:10.20944/preprints202309.0906.v3

Establishment of a Novel Cancer-Specific Anti-HER2 Monoclonal Antibody H2Mab-250/H2CasMab-2 for Breast Cancers

Mika K Kaneko, Hiroyuki Suzuki, Tomokazu Ohishi, Tomohiro Tanaka, Yukinari Kato

Subject: Oncology And Oncogenics, Medicine And Pharmacology Keywords: HER2; cancer-specific monoclonal antibody; screening; epitope; flow cytometry

Online: 28 November 2023 (03:35:30 CET)

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Preprint ARTICLE | doi:10.20944/preprints202311.1695.v1

Simulation of Pollutants Trajectory in the Black Sea Region Atmosphere with Different Spatial Resolution

Alexander A. Egorkin, Elena N. Voskresenskaya, Viktor Y. Zhuravskiy

Subject: Atmospheric Science And Meteorology, Environmental And Earth Sciences Keywords: trajectories; reanalys data set; HYSPLIT model; WRF model

Online: 28 November 2023 (03:23:29 CET)

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Preprint ARTICLE | doi:10.20944/preprints202311.1702.v1

Dividing Time – An Absolute Chronological Study of Material Culture from Early Iron Age Urnfields in Denmark

Helene Rose, John Meadows

Subject: Archaeology, Arts And Humanities Keywords: Archaeology; Early Iron Age; typology; cremated bone; radiocarbon dating; Bayesian chronological modelling

Online: 28 November 2023 (02:02:39 CET)

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Chronological frameworks based on artefact typologies are essential for interpreting the archaeological record, but they inadvertently treat transitions between phases as abrupt events and disregard the temporality of transformation processes within and between individual phases. This study presents an absolute chronological investigation of a dynamic material culture from Early Iron Age urnfields in Denmark. The chronological framework of Early Iron Age in Southern Scandinavia is largely unconstrained by absolute dating, primarily due to it coinciding with the so-called ‘Hallstatt calibration plateau’ (c.750 to 400 cal BC), and it is difficult to correlate it with Central European chronologies due to a lack of imported artefacts. This study applies recent methodological advances in radiocarbon dating and Bayesian chronological modelling, specifically a statistical model for wood-age offsets in cremated bone and presents the first large-scale radiocarbon investigation of regional material culture from Early Iron Age in Southern Jutland, Denmark. Dated material is primarily cremated bone from 111 cremation burials from three urnfields. The study presents absolute date ranges for 16 types of pottery and 15 types of metalwork, which include most of the recognised metalwork types from the period. This provides new insights into gradual change in material culture, when certain artefact types were in production and primary use, how quickly types were taken up and later abandoned, and distinguishing periods of faster and slower change. The study also provides the first absolute chronology for the period, enabling correlation with chronologies from other regions. Urnfields were introduced at the Bronze-Iron Age transformation, which is often assumed to have occurred c.530-500 BC. We demonstrate that this transformation took place in the 7^th century BC, however, which revives the discussion of whether the final Bronze Age period VI should be interpreted as a transitional phase to the Iron Age.

Preprint ARTICLE | doi:10.20944/preprints202311.1618.v1

Beyond Gender: Interoceptive Sensibility as a Key Predictor of Body Image Disturbances

Akansha M. Naraindas, Marina Moreno, Sarah M. Cooney

Subject: Psychology, Social Sciences Keywords: body image; body schema; gender; interoception; motor imagery

Online: 28 November 2023 (01:45:38 CET)

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Preprint ARTICLE | doi:10.20944/preprints202311.1619.v1

Effect of Fertilization with Increasing Doses of Ammonium Nitrate on Growth, Yield, and Concentration of N, P, and K in Leaves of Olive Trees (Olea Europea L.) c.v. “Kalinioti”

Christos Pappas, Victor Kavvadias

Subject: Agricultural Science And Agronomy, Biology And Life Sciences Keywords: Olive trees; Nitrogen fertilization; yield; leaf concentration; fruit set

Online: 28 November 2023 (01:45:24 CET)

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Preprint REVIEW | doi:10.20944/preprints202311.1632.v1

An Ailment with Which I Will Contend’: A Narrative Review of 5,000 Years of Esophagogastric Cancers and Their Treatments, with Special Emphasis on Recent Advances in Immunotherapeutics

C. Beau Hilton, Steven Lander, Michael K Gibson

Subject: Oncology And Oncogenics, Medicine And Pharmacology Keywords: checkpoint inhibitors; esophageal cancer; gastric cancer; immunotherapy; PD-L1; HER2; clinical trials; history; disparities

Online: 28 November 2023 (01:45:08 CET)

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Preprint REVIEW | doi:10.20944/preprints202311.1630.v1

Recent Advances in the Numerical Solution of the Nonlinear Schrödinger Equation

Luigi Barletti, Luigi Brugnano, Gianmarco Gurioli, Felice Iavernaro

Subject: Other, Physical Sciences Keywords: Nonlinear Schrö; dinger Equation; NLSE; energy-conserving methods; Hamiltonian Boundary Value Methods; HBVMs; spectral accuracy

Online: 28 November 2023 (01:44:26 CET)

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Preprint ARTICLE | doi:10.20944/preprints202311.1621.v1

DEPDC1 Promotes Thyroid Cancer Migration, Invasion, and Proliferation, and Correlates with Poor Prognosis

Haosheng Tan, Hui Huang, Huaiyu Yang, Jiaxin Qian, Liyuan Wei, Wensheng Liu

Subject: Oncology And Oncogenics, Medicine And Pharmacology Keywords: DEPDC1; Dedifferentiation; Expression correlation; Cancer progression; Prognosis

Online: 28 November 2023 (01:42:00 CET)

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Background: We screened key genes involved in the dedifferentiation process of thyroid cancer by analyzing differentially expressed genes in anaplastic thyroid carcinoma (ATC) using Gene Expression Omnibus (GEO) database. Methods: We analyzed differentially expressed genes in ATC from GEO database and constructed a co-expression network using Weighted Gene Co-expression Network Analysis (WGCNA) . Cytoscape was used to calculate top ten key genes based on their gene scores. DEPDC1 was selected as interest gene for further validation, including examination of its prognostic relationship with thyroid cancer, correlation analysis with thyroid differentiation markers, immune cell infiltration, and tumor microenvironment. The impact of DEPDC1 on cancer cell migration, invasion, and proliferation was validated through downregulation and overexpression of DEPDC1 gene in thyroid cancer cell lines c643 and BCPAP. Results: We identified top 10 key genes in ATC: AURKA, TPX2, RACGAP1, MELK, DLGAP5, DEPDC1, KIF2C, NCAPG, CCNB1, and PBK. DEPDC1 showed a strong correlation with the prognosis of thyroid cancer. The odds ratio (OR) for overall survival was 3.5 (P=0.016) in individuals with high DEPDC1 expression, and the OR for disease-free survival was 2.6 (P=0.003). Additionally, the analysis revealed a significant negative correlation between the expression of DEPDC1 and thyroid differentiation markers. Gene Ontology enrichment analysis demonstrated that DEPDC1 co-expressed genes were enriched in cellular processes, cell cycle pathways, and dynamic protein groups. Matrix and immune scoring indicated tumor microenvironment and immune scores were associated with DEPDC1 expression. TIMER2.0 online analysis revealed a strong correlation between DEPDC1 expression and immune cell infiltration in papillary thyroid carcinoma. After downregulation of DEPDC1 expression, the invasion, migration, and proliferation abilities of tumor cells were significantly reduced. Conversely, overexpression of DEPDC1 exhibited the opposite effect. Conclusion: DEPDC1, a newly identified dedifferentiation gene in thyroid cancer, inversely correlated with the degree of differentiation. High expression of DEPDC1 promotes cancer progression and leads to poor prognosis in thyroid cancer.

Preprint ARTICLE | doi:10.20944/preprints202311.1639.v1

A high-flux compact X-ray free-electron laser for next-generation chip metrology needs

James B. Rosenzweig, Gerard Andonian, Ronald Agustsson, Petr M. Anisimov, Aurora Araujo, Fabio Bosco, Martina Carillo, Enrica Chiadroni, Luca Giannessi, Zhirong Huang, Atsushi Fukasawa, Dongsung Kim, Sergey Kutsaev, Gerard Lawler, Zenghai Li, Nathan Majernik, Pratik Manwani, Jared Maxson, John Miao, Mauro Migliorati, Andrea Mostacci, Pietro Musumeci, Alex Murokh, Emilio Nanni, Sean O’Tool, Luigi Palumbo, River Robles, Yusuke Sakai, Evgenya I. Simakov, Madison Singleton, Bruno Spataro, Jingyi Tang, Sami Tantawi, Oliver Williams, Haoran Xu, Monika Yadav

Subject: Applied Physics, Physical Sciences Keywords: metrology; semiconductor; ptychography; laminography; free-electron laser; photoinjector; beam dynamics; undulator; coherence; x-ray

Online: 28 November 2023 (01:41:43 CET)

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Preprint ARTICLE | doi:10.20944/preprints202311.1627.v1

Application of Petrographic and Stereological Analyses to Describe the Pore Space of Rocks as a Standard for the Characterization of Pores in Slags and Ashes Generated after the Combustion of Municipal Waste

Katarzyna Godyń, Barbara Dutka, Maciej Tram

Subject: Environmental Science, Environmental And Earth Sciences Keywords: microscopic analysis; petrography; porosity; slags and ashes; municipal waste

Online: 28 November 2023 (01:41:31 CET)

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Preprint REVIEW | doi:10.20944/preprints202311.1643.v1

Vaccinating Against a Novel Pathogen: A Critical Review of COVID-19 Vaccine Effectiveness Evidence

Bernard Black, David B Thaw

Subject: Health Policy And Services, Public Health And Healthcare Keywords: COVID-19; SARS-CoV-2; vaccine; vaccine efficacy; vaccine effectiveness, vaccine booster; BNT162b2; mRNA1273; Ad26.COV2.S; ChAdOx1-S; SARS-CoV-2 variants

Online: 28 November 2023 (01:41:16 CET)

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Preprint ARTICLE | doi:10.20944/preprints202311.1638.v1

Using the ISO 9705 Room Corner Test for Smoke Toxicity Quantification of Oriented Strand Board

Gabrielle Peck

Subject: Physical Chemistry, Chemistry And Materials Science Keywords: Smoke Toxicity; Large-Scale; Oriented Strand Board; ISO 9705; Flammability

Online: 28 November 2023 (01:40:57 CET)

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Preprint ARTICLE | doi:10.20944/preprints202311.1624.v1

The Influence of Innovative and Traditional Cabernet Sauvignon Winemaking Technology and Wine Aging on Stilbenes and Other Polyphenolic Compounds

Aleksandar Petrović, Nikolina Živković, Ljilja Torović, Ana Bukarica, Vladan Nikolić, Jelena Cvejić, Ljiljana Gojkovic-Bukarica

Subject: Food Science And Technology, Biology And Life Sciences Keywords: innovative technology; Torulaspora delbrueckii, non-Saccharomyces yeast, phenolic compounds; trans-resveratrol; quercetin

Online: 28 November 2023 (01:40:46 CET)

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Preprint ARTICLE | doi:10.20944/preprints202311.1620.v1

AI-based Nano-scale Material Property Prediction For Li-Ion Batteries

Mohit Anil Lal, Akashdeep Singh, Ryan Mzik, Amirmasoud Lanjan, Seshasai Srinivasan

Subject: Materials Science And Technology, Chemistry And Materials Science Keywords: Quantum Mechanics; Molecular Dynamics; battery materials; Artificial Intelligence; Machine Learning; Nanotechnology

Online: 28 November 2023 (01:40:28 CET)

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Preprint ARTICLE | doi:10.20944/preprints202311.1628.v1

An Agent-Based Model for Determining the Agriculture Demand Based on Farmers' Socio-Economic Characteristics

Milad Basirifard, Icen Yoosefdoost

Subject: Civil Engineering, Engineering Keywords: Agriculture Demand; Agricultural Risk; Agent-Based Model; Standard Operating Policy

Online: 28 November 2023 (01:39:57 CET)

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Preprint ARTICLE | doi:10.20944/preprints202311.1649.v1

Phylogenetic and Proteomic Analysis of Pyruvate-Ferredoxin Oxidoreductase; a Redox Enzyme Involved in the Pharmacological Activation of Nitro-Based Prodrugs in Protozoan and Bacterial Species

Seth Duwor, Pascal Mäser, Daniela Brites

Subject: Life Sciences, Biology And Life Sciences Keywords: Pyruvate-ferredoxin oxidoreductase; metronidazole; reductive bio-activation; antimicrobial spectrum; omparative bioinformatics; horizontal gene transfer; phylogeny

Online: 28 November 2023 (01:39:45 CET)

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Introduction: The distribution of typical bacterial redox enzymes such as pyruvate-ferredoxin oxidoreductase (PFOR) in protozoa remains interestingly puzzling. Previous studies have demonstrated diverse cellular localizations of PFOR in amitochondriate anaerobic protozoa such as Trichomonas vaginalis. PFOR is of particular pharmacological importance because it catalyzes the reductive bio-activation of nitro-based prodrugs to cytotoxic radical metabolites. Metronidazole was developed primarily as an antiprotozoal agent against infections caused by T. vaginalis. However, its antimicrobial spectrum was subsequently expanded to cover anaerobic bacterial infections. It has been shown that mutations in the genes encoding PFOR result in inherent resistance of T. vaginalis and anaerobic bacteria to metronidazole. Aims: To analyze the phylogenetic distribution of PFOR in selected protozoa and bacteria using proteins encoded by housekeeping genes as controls. Using comparative bioinformatics to test the hypothesis that PFOR was most likely acquired through horizontal gene transfer from bacteria, proteome-wide analysis and gene expression analysis to identify other genes that were putatively acquired through horizontal gene transfer from bacteria to protozoa. Methods: Sequence similarity queries were performed using the proteins of interest against the NCBI non-redundant protein sequence database with BLASTP version 2.12.0+ from the NCBI website. Multiple sequence alignments were performed with MEGA version X software using the Muscle algorithm. These were then exported in Mega format to construct phylogenetic trees using the neighbor-joining algorithm and the Poisson substitution model. Complete proteomes of representative protozoan and bacterial species were downloaded in fasta format from the ensemblgenomes database. HMM profile libraries were used to screen the proteomes with hmmscan of the HMMer package. Whole proteome BLAST searches were performed between protozoan species of interest against closely related protozoa. The results were compared to the proteome BLAST against the intestinal bacteria Desulfovibrio vulgaris. Gene enrichment analysis was performed between the exclusively present proteins in the protozoa and D. vulgaris. Only results with p-values <0.05 were considered for analysis. Results and conclusions: A plausible explanation for the restricted occurrence of PFOR in protozoa is based on the hypothesis that bacteria serve as potential sources of genes that enhance optimal adaptation of protozoa in hostile environments. The expanded cladograms of Entamoeba and Cryptosporidium with their closely related genera substantiated this hypothesis. The exclusively expressed proteins obtained from E. histolytica and the putative bacterial gene donor, D. vulgaris, showed an over-representation of eleven genes involved in small molecule metabolism, generation of precursor metabolites, and carbohydrate metabolism. If these results can be reproduced in other PFOR-possessing protozoa, it would provide a more validated evidence to support the horizontal transfer of pfor from bacteria. Subsequent syntenic analyses of the significantly enriched genes would be required to provide further information regarding the positional relatedness of these genes at the chromosomal level. Since metronidazole is an established and well tolerated drug for treating infections caused by PFOR-possessing pathogens, it can be considered as a potential drug candidate for the treatment of infections caused by Cryptosporidium, Spironucleus and Blastocystis.

Preprint REVIEW | doi:10.20944/preprints202311.1629.v1

A Synthesis of Biogenic Nanoparticles (NPs) for the Treatment of Wastewater and Its Application: A Review

Prangya Rath, Laxmi Kant Bhardwaj, Poornima Yadav, Abhishek Bhardwaj

Subject: Environmental Science, Environmental And Earth Sciences Keywords: Nanoparticles (NPs); Biogenic/Green synthesis; Wastewater treatment; Water pollutants

Online: 28 November 2023 (01:25:21 CET)

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Preprint ARTICLE | doi:10.20944/preprints202311.1727.v1

In Silico Exploration of Bisphosphonate Scaffolds as Potential Inhibitors of SARS-CoV-2 RdRp for COVID-19 and PASC

Muzaffar-Ur-Rehman Mohammed, Kishore Suryakant Chougule, Chandu Ala, Pranali Vijaykumar Kuthe, Mohit Garg, Murugesan Sankaranarayanan, Seshadri S Vasan

Subject: Chemistry And Materials Science, Medicinal Chemistry Keywords: Bisphosphonates; Long COVID; MM-GBSA; Molecular docking; Molecular dynamics; RdRp; SARS-CoV-2; Virtual screening

Online: 27 November 2023 (16:52:17 CET)

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Preprint CASE REPORT | doi:10.20944/preprints202311.1726.v1

Atypical Milroy's Disease with Predominant Unilateral İnvolvement: A Case Report

Songül Keskin kavak

Subject: Medicine And Pharmacology, Clinical Medicine Keywords: Hereditary lymphedema type I,; inherited primary lymphedema,; Milroy's Disease; Complete Decongestive Therapy,

Online: 27 November 2023 (16:51:24 CET)

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Preprint ARTICLE | doi:10.20944/preprints202311.1718.v1

A Comparison of Two Connectivity Reduction Methods for Spiking Neural Networks with Memristive Plasticity

Roman Rybka, Yury Davydov, Danila Vlasov, Alexey Serenko, Alexander Sboev, Vyacheslav Ilyin

Subject: Computer Science And Mathematics, Artificial Intelligence And Machine Learning Keywords: spiking neural networks; neuromorphic computing; STDP; memristive plasticity; sparse connectivity; sound classification; image classification

Online: 27 November 2023 (16:13:33 CET)

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Preprint ARTICLE | doi:10.20944/preprints202311.1723.v1

A Comparison of GaN Transistors to MOSFETs for Active Magnetic Levitation

Alexander H. Pesch, Nyandieka H. Aboki, Jairo E. Villamizar-Vasquez, Frank Li, Vamsi Borra

Subject: Engineering, Electrical And Electronic Engineering Keywords: magnetic bearings; MOSFETs; gallium nitride; GaN

Online: 27 November 2023 (16:12:47 CET)

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Preprint REVIEW | doi:10.20944/preprints202311.1724.v1

Neuroinflammation and Neurodegenerative Diseases: How Much Do We Still Not Know?

Carmela Rita Balistreri, Roberto Monastero

Subject: Medicine And Pharmacology, Neuroscience And Neurology Keywords: Neuroinflammation; neurodegenerative diseases; emerging mechanisms.

Online: 27 November 2023 (16:11:41 CET)

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