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Preprint ARTICLE | doi:10.20944/preprints202309.1725.v1

Characteristics of Silica Fume Nano-Alumina Ternary Blended Mortar

Moruf Olalekan Yusuf

Subject: Civil Engineering, Engineering Keywords: strength; supplementary cementitious materials; silica fume binder; nano alumina particle; thermal resistance; microstructural characterization.

Online: 26 September 2023 (03:50:40 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202309.1723.v1

Simple Sequence Repeats-Based DNA Fingerprinting and Varietal Identification of Mango Cultivars

Javed Iqbal, Muhammad Aleem Ashraf, Qiuliang Cai, Ammara Riaz, Yufeng Li, Imran Shahid, Yu Kong, Abdul Ghaffar Grewal, Sidra Kiran, Sajid Rehman, Imran Habib, Naitong Yu

Subject: Biology And Biotechnology, Biology And Life Sciences Keywords: Mango tree; SSR markers; mango varieties; genetic diversity; cultivar identification diagram, loci, polymorphism; genetic resources in Pakistan; breeding; cultivar development

Online: 26 September 2023 (03:48:00 CEST)

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Assessment of the genetic distinctiveness of a cultivar through morphological descriptors is an important tool for both the registration and the protection. New mango genotypes have been improved using valuable diverse germplasm resources to ensure food security. DNA fingerprinting based simple sequence repeats (SSR)-markers have been the most broadly used, effective and accurate in evaluation of genetic characterization of a cultivar. Molecular breeding is an effective source of genetic gain after improvement of fruit trees using marker assisted genomic selection. Mango (Mangifera indica L.) is an allotetraploid (2n = 4X= 40) drupe fruit and has high nutritional value belongs to genus Mangifera and family Anacardiaceae. Mango cultivars are used with worldwide acceptance to pharmacological, ethnomedical, and phytochemical industries. This study investigated the molecular evaluation of a new mango cultivar ‘Azeem Chaunsa’ using a set of the most effective 50 hyper-variable polymorphic SSR markers. Highly specific DNA fingerprints were identified in the genome of this mango cultivar, ‘Azeem Chaunsa’ compared with three standard cultivars such as Sindhri, Samar Bahisht (S.B) Chaunsa and Sufaid Chaunsa. Our results showed that SSR markers could efficiently assess genetic diversity in mango. An agglomerative hierarchical clustering method was used to construct dendrogram based on the ‘Unweighted Pair- Group Method with Arithmetic Mean’ (UPGMA). The genetic similarity coefficients were recorded between the mangos cultivars ranged from 0.49 to 0.67. Cultivar identification (CID) evaluates association among standard cultivars and Azeem Chaunsa and further concludes significant variations. CID results concluded that cultivar ‘Azeem Chaunsa’ varied significantly from the check cultivar, Sindhri (46.2%), S.B Chaunsa (45%) and Sufaid Chaunsa (46.7%). The results obtained in this study will orient cultivar identification strategies for a successful future mango breeding programmes in the context of climate change.

Preprint ARTICLE | doi:10.20944/preprints202309.1641.v1

Dietary Habits, Meal-Timing, and Meal Frequency in Kuwaiti Adults: Analysis of the Kuwait National Nutrition Surveillance Data

Fatema Alkhulaifi, Suad Al-Hooti, Sameer Al-Zenki, Husam Alomirah, And Charles Darkoh

Subject: Behavioral Sciences, Biology And Life Sciences Keywords: dietary habits; meal timing; meal frequency; late night dinner; skipping meals; Kuwait

Online: 26 September 2023 (03:23:15 CEST)

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Preprint COMMUNICATION | doi:10.20944/preprints202309.1645.v1

Potential Tick Defense Associated with Skin and Hair Characteristics in Korean Water Deer (Hydropotes inermis argyropus)

Sang-Joon Lee, Ki-Yoon Kim, Gyurae Kim, Subin Moon, Yung Chul Park, Ho-Seong Cho, Yeonsu Oh

Subject: Animal Science, Veterinary Science And Zoology, Biology And Life Sciences Keywords: Korean water deer; skin tissue; hair characteristics; comparative pathology; tick bites

Online: 26 September 2023 (03:22:22 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202309.1656.v1

Patterns and Determinants of Synonymous Codon Usage in Mulberry Mosaic Dwarf Associated Virus

XingNan Zhang, Jing Song, LongHui Luo, Xun xun Sun, JiPing Liu

Subject: Agricultural Science And Agronomy, Biology And Life Sciences Keywords: MMDaV; Mulberry; Synonymous codons; Geminiviridae; Codon usage

Online: 26 September 2023 (03:19:44 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202309.1655.v1

Unveiling the Magnetic and Structural Properties of (X2YZ; X = Co & Ni, Y = Fe & Mn and Z = Si) Full Heusler Alloy Microwires with Fixed Aspect Ratio

Mohamed Salaheldeen, Valentina Zhukova, Mihail Ipatov, Arcady Zhukov

Subject: Materials Science And Technology, Chemistry And Materials Science Keywords: Full-Heusler alloys; Glass-coated microwires; magnetic behavior; Sensing Applications

Online: 26 September 2023 (03:16:45 CEST)

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We studied Ni2FeSi, Co2FeSi and Co2MnSi -based full Heusler alloy glass-coated microwires with the same geometric aspect ratio ρ ≈ 0.50 ± 0.01 prepared using Taylor-Ulitovsky method. The fabrication of X2YZ; (X = Co & Ni, Y = Fe & Mn and Z = Si) based glass coated microwires with fixed aspect ratio is a quite challenging due to the different samples preparation conditions. The XRD analysis shows nanocrystalline microstructure for all the samples. Space group Fm3¯m (FCC) with disordered B2 and A2-types for Ni2FeSi and Co2FeSi and ordered L21-type for Co2MnSi are observed. The change in the positions of Ni, Co and Mn, Fe in X2YSi resulted in a variation in the lattice cell parameters and the average grain size of the sample. Room temperature magnetic behavior shows a dramatic change depending on the chemical composition, where Ni2FeSi-MWs shows the highest coercivity (Hc) compared to Co2FeSi-MWS and Co2MnSi-MWs. The Hc –value of Ni2FeSi-MWs is 16 times higher than that of Co2MnSi-MWs and 3 times higher than that of Co2FeSi-MWS. Meanwhile, the highest reduced remanence is reported for Co2FeSi-MWS (Mr =0.92), , being about 0.33 and 0.22 for Ni2FeSi-MWs and Co2MnSi-MWs, respectively. From the analysis of the temperature dependence of the magnetic properties (Hc and Mr) of X2YZ-MWs we deduced that Hc shows a stable tendency for Co2MnSi-MWs and Co2FeSi-MWs, meanwhile two flipped points are observed for Ni2FeSi-MWs where the behavior of Hc changes with temperature. For Mr monotonic increase by decreasing the temperature is observed for Co2FeSi-MWs and Ni2FeSi-MWs and roughly stable for Co2MnSi-MWs. The thermomagnetic curves at low magnetic field show irreversible magnetic behavior for Co2MnSi-MWs and Co2FeSi-MWs and regular ferromagnetic behavior for Ni2FeSi-MWs. The current result illustrates the ability to tailor the structure and magnetic behavior of X2YZ-MWs at a fixed internal stresses, i.e., with fixed aspect ratio. Additionally, a different behavior was revealed in X2YZ-MWs depending on the degree of ordering and elements distribution. The tunability of magnetic properties of X2YZ-MWs makes them suitable for sensing applications.

Preprint ARTICLE | doi:10.20944/preprints202309.1671.v1

Developing a Convenience Store Product Recommendation System through Store-Based Collaborate Filtering

Jae Kyung Lee, Jinho Kim

Subject: Other, Business, Economics And Management Keywords: recommendation models; store-based recommendation models; implementation of recommender system

Online: 26 September 2023 (03:12:05 CEST)

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Recently, e-commerce companies have been adopting and continuously enhancing personalized product recommendation systems, and there is active research in this field within academia. However, personalized product recommendations in offline retail stores have not yielded significant outcomes thus far. Especially for small-format offline retail businesses like convenience stores, where customer information might be limited, providing personalized product recommendations poses even greater challenges. To address this issue, this study aimed to find a solution by shifting the perspective on recommendation methods and altering the target of recommendations in existing personalized recommendation models. In this study, recommending products that customers need in an offline store was defined as suggesting products that should be introduced and displayed within the store. In other words, the recommendation focus shifted from individuals to the stores themselves. This recommendation system proposes products that individual stores have not yet introduced but are anticipated to be purchased by customers among the products managed by the headquarters. Building upon this, we devised a store-based product recommendation system. The widely used user-based collaborative filtering model, a common technique in existing recommendation systems, was adapted into a store-based collaborative filtering model. Furthermore, various rules and logic pertinent to store operations and business considerations for convenience stores were integrated to implement this store product recommendation system. The accuracy and effectiveness of the system were demonstrated through its application in actual convenience stores. Results from the pilot implementation of the system showed that 88% of the newly recommended products in individual stores were sold based on one week of sales data, and the sales revenue was 1.75 times higher than the average sales revenue of those products across the entire company. Survey results on business owners' satisfaction yielded a score of 4.2 out of 5, indicating a high level of contentment. Additional observed effects included the expansion of product range and reduction in order lead times. However, 12% of the total recommended SKUs did not sell within one week, and 34% of the SKUs did not meet the overall average sales quantity. This research holds significance in extending the scope of personalized recommendation studies from primarily online platforms to offline retail businesses like convenience stores. It provides tangible methodologies and outcomes that can be implemented in real-world settings through the construction and validation of an actual system. The study also suggests avenues for future research to address some of the identified limitations.

Preprint ARTICLE | doi:10.20944/preprints202309.1636.v1

Auditory Challenges and Listening Effort in School-Age Children with Autism: Insights from Pupillary Dynamics during Speech in Noise Perception

Suyun Xu, Hua Zhang, Juan Fan, Xiaoming Jiang, Minyue Zhang, Jingjing Guan, Hongwei Ding, Yang Zhang

Subject: Language And Linguistics, Social Sciences Keywords: Autism spectrum conditions; Atypical resource allocation; Listening effort; Pupillometry; Speech-in-noise recognition

Online: 26 September 2023 (03:10:24 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202309.1632.v1

Determination of Significant 3D Hemodynamic Features for Post-Embolization Recanalization in Cerebral Aneurysms through Explainable Artificial Intelligence

Jing Liao, Kouichi Misaki, Mitsutoshi Nakada, Tekehiro Uno, Jiro Sakamoto

Subject: Artificial Intelligence And Machine Learning, Computer Science And Mathematics Keywords: CFD; DNN; XAI; PointNet; flow pattern; cerebral aneurysm; recanalization

Online: 26 September 2023 (03:05:56 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202309.1614.v1

Analysis of the Performance of a Hybrid Thermal Power Plant Using Anfis-Based Approaches

Kantu T. Kabengele, Isaac Oyeyemi Olayode, Lagouge K. Tartibu

Subject: Mechanical Engineering, Engineering Keywords: Performance; Hybrid thermal power plant; Integrated solar combined cycle power plant (ISCCPP); Adaptive Neuro-Fuzzy Inference System (ANFIS); Particle Swarm Optimization (PSO); Genetic Algorithm (GA); ANFIS-PSO; ANFIS-GA; Evolutionary algorithms

Online: 26 September 2023 (02:59:35 CEST)

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The hybridization of conventional thermal power plants by incorporation of renewable energy systems has witnessed widespread adoption in recent years. This trend aims not only to mitigate carbon emissions but also to enhance the overall efficiency and performance of these power generation facilities. However, calculating the performance of such intricate systems using fundamental thermodynamic equations proves to be both laborious and time-intensive. Nevertheless, possessing accurate and real-time insights into their performance is of utmost significance to ensure optimal plant operation, facilitate decision-making, and streamline power production planning. In this paper, we delve into the application of machine learning techniques, particularly hybrid methodologies, to predict the performance of power plants. Specifically, we employ three approaches: the Adaptive Neuro-Fuzzy Inference System (ANFIS), the ANFIS optimized via Particle Swarm Optimization (ANFIS-PSO), and the ANFIS optimized through Genetic Algorithm (ANFIS-GA). These techniques are alternatively applied to a complex hybrid thermal power plant, namely an Integrated Solar Combined Cycle Power Plant (ISCCPP). This ISCCPP comprises a steam turbine section, a gas turbine section, and a concentrated solar power system utilizing troughs as collectors. The energy transfer fluid, in conjunction with exhaust from the gas turbine section, heats water within a vessel or steam generator, producing steam to propel the steam turbine's rotor. Electricity generation is facilitated by both gas and steam turbines, which are coupled to a generator. The findings of this study underscore the accuracy and appropriateness of ANFIS-based models in evaluating and predicting the performance of intricate hybrid power plants. The ANFIS model exhibited an impressive overall coefficient of correlation of 0.9991. Notably, the integration of evolutionary algorithms (PSO and GA) into the ANFIS framework elevated model performance, yielding correlation coefficients of 0.9994 for ANFIS-PSO and 0.9997 for ANFIS-GA. It is noteworthy that ANFIS-GA demonstrated superior predictive capability. The modeling framework developed in this research offers valuable support to designers, energy managers, and decision-makers. It provides a robust and dependable tool to assess the performance of hybrid thermal power plants, which are poised for a global surge in numbers amid the ongoing energy transition.

Preprint ARTICLE | doi:10.20944/preprints202309.1530.v1

The Relative Values of a Moisture Percentage in Building Envelopes: Moisture's Spots With a Moisture Meter

JOVANA JOVANOVIĆ, Ivan Stevović

Subject: Civil Engineering, Engineering Keywords: hygrothermal traits; moisture percentage; wall lining systems; moisture meter; building envelope

Online: 26 September 2023 (02:57:35 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202309.1609.v1

Unlocking the Potential: Lucid Dreaming as a Tool for Development and Innovation

Brigitte Holzinger, Severin Ableidinger

Subject: Other, Arts And Humanities Keywords: lucid dreaming practice; creativity; insights; martial arts; sport; interview; qualitative; lucid dreaming

Online: 26 September 2023 (02:52:24 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202309.1620.v1

Identification of Reference Genes for Precise Expression Analysis during Germination in Chenopodium quinoa Seeds under Salt Stress

ESTEFANIA CONTRERAS, Lucía Martín-Fernández, Arafet Manaa, Jesús Vicente-Carbajosa, RAQUEL IGLESIAS-FERNANDEZ

Subject: Biochemistry And Molecular Biology, Biology And Life Sciences Keywords: Chenopodium quinoa; Germination sensu stricto; Reference gene; quantitative PCR; Salt stress; Seed

Online: 26 September 2023 (02:51:17 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202309.1658.v1

Effects of Structural Relaxation of Glass-forming Melts on the Overall Crystallization Kinetics in Cooling and Heating

Jürn W. P. Schmelzer, Timur V. Tropin, Christoph Schick

Subject: Condensed Matter Physics, Physical Sciences Keywords: nucleation; thermodynamics of nucleation; general theory of phase transitions; theory and models of crystal growth

Online: 26 September 2023 (02:49:52 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202309.1627.v1

Comparison of Unilateral versus Bilateral Instrumented Transforaminal Lumbar Interbody Fusion in Lumbar Degenerative Diseases: A Minimum of 5-Year Follow-Up

Sung Cheol Park, Jae Seong Bae, Seon Ok Jung, Kyeong-Hoon Sung, Hoon-Jae Chung

Subject: Orthopedics And Sports Medicine, Medicine And Pharmacology Keywords: Transforaminal lumbar interbody fusion; TLIF; Unilateral instrumentation; Bilateral instrumentation; Coronal alignment; Long-term outcome

Online: 26 September 2023 (02:48:02 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202308.1782.v2

Geopolymer Composites: Manufacturing of Sandwich Steel and Geopolymer Structures with Spray Technology without Formwork

Su Van Le, Kinga Pławecka

Subject: Surfaces, Coatings And Films, Chemistry And Materials Science Keywords: porous geopolymer composites; fire resistance; alkali activation; surface coatings; thermal insula-tion; mechanical properties; cost-effectiveness

Online: 26 September 2023 (02:47:00 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202309.1694.v1

Integrated Remote Sensing Investigation for Suspected Landslide: A Case Study of the Genie Slope in the Sichuan-Tibet Transportation Corridor, China

Wenlong Yu, Weile Li, Huiyan Lu, Zhengxuan Xu, Dong Wang, Xiujun Dong, Pengfei Li

Subject: Remote Sensing, Environmental And Earth Sciences Keywords: optical remote sensing; LiDAR; Stacking-InSAR; SBAS-InSAR; slope deformation; stability

Online: 26 September 2023 (02:38:33 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202308.1582.v2

Bacterial Products and Their Effect in the Shrubby Legume Calicotome Villosa (Poir.) Link

María A. Pérez-Fernández, Irene Ariadna De-Lara-del-Rey, Anathi Magadlela

Subject: Plant Sciences, Biology And Life Sciences Keywords: legumes; siderophores; IAA; biomass; bacterial richness

Online: 26 September 2023 (02:24:00 CEST)

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Preprint REVIEW | doi:10.20944/preprints202309.1692.v1

Smart Packaging Based on Polylactic Acid: Effect of Antibacterial and Antioxidant Agents from Natural Extract on Physical-Mechanical Properties, Colony Reduction, and Perishable Food Shelf Life

Halimatuddahliana Nasution, Hamidah Harahap, Elisa Julianti, Aida Safitri, Mariatti Jaafar

Subject: Materials Science And Technology, Chemistry And Materials Science Keywords: Colony reduction; Food shelf life; Mechanical properties; Natural additive; PLA; Smart packaging

Online: 26 September 2023 (02:18:14 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202309.1690.v1

Automatic Roadside Camera Calibration with Transformers

Yong Li, Zhiguo Zhao, Yunli Chen, Xiaoting Zhang, Rui Tian

Subject: Computer Vision And Graphics, Computer Science And Mathematics Keywords: Camera Calibration; Vanishing Point Detection; Transformer

Online: 26 September 2023 (02:15:36 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202309.1685.v1

Effectiveness of a Mechanical Ventilation System for Indoor PM2.5 in Residential Houses

Dongho Shin, Younghun Kim, Kee-Jung Hong, Gunhee Lee, Inyong Park, Hak-Joon Kim, Sangwoo Kim, Cheong-Ha Hwang, Kwang-Chul Noh, Bangwoo Han

Subject: Public, Environmental And Occupational Health, Public Health And Healthcare Keywords: Mechanical ventilation; CADR; PM2.5; MERV; Residential house

Online: 26 September 2023 (02:10:27 CEST)

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Preprint REVIEW | doi:10.20944/preprints202309.1713.v1

miR125-Centered ceRNETs in Breast Cancer. Clinical, Molecular and Ethical Aspects in Personalized Medicine

Roberto Piergentili, Giuseppe Gullo, Gaspare Cucinella, Alessandra Lopez, Gabriele Napoletano, Enrico Marinelli, Simona Zaami

Subject: Medicine And Pharmacology, Obstetrics And Gynaecology Keywords: Breast Cancer (BC); MicroRNAs (miRNAs); non-coding RNA; competing endogenous RNA (ceRNA); personalized medicine; ethical and legal challenges

Online: 25 September 2023 (16:47:32 CEST)

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Preprint REVIEW | doi:10.20944/preprints202305.0720.v2

Unlocking the Secrets of Androgen Receptors in the Susceptibility, Progression, and Treatment of Prostate Cancer

Suleiman Zakari, Christogonus C. Ekenwaneze, Emmanuel C. Amadi, Olubanke O. Ogunlana

Subject: Biology And Life Sciences, Biochemistry And Molecular Biology Keywords: Prostate cancer; androgen receptor; AR signaling pathway; disease progression; therapeutic re-sistance; personalized treatment; androgen deprivation therapy; AR-targeted therapies

Online: 25 September 2023 (16:46:10 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202309.1602.v1

Comparative Study of Deterioration in Built Heritage in a Coastal Area: Barbanza Peninsula (Galicia, NW of Spain)

Ana C. Hernández, Jorge Sanjurjo-Sánchez, Carlos Alves, Carlos A. M. Figueiredo

Subject: Environmental And Earth Sciences, Other Keywords: weathering; granite; built heritage; decay; salts; biological colonization.

Online: 25 September 2023 (13:05:26 CEST)

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Preprint COMMUNICATION | doi:10.20944/preprints202309.1607.v1

New Nonlinear Coupled Model for Modeling the Vortex Induced Vibrations of Flexibly Supported Circular Cylinders

Shujun Zhang, Aref Afsharfard, Guanbin Chen, Wen-Li Chen, Kyung Chun Kim

Subject: Engineering, Mechanical Engineering Keywords: Vortex-Induced vibration; Wake oscillator equation; Numerical simulation; Nonlinear modeling

Online: 25 September 2023 (13:04:13 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202309.1618.v1

Differences Changes in Cerebellar Functional Connectivity of Parkinson's patients with visual hallucinations

Liangcheng Qu, Chuan Liu, Yiting Cao, Kuiying Yin, Weiguo Liu, Jingping Shi

Subject: Medicine And Pharmacology, Neuroscience And Neurology Keywords: Parkinson's disease; visual hallucinations; cerebellum; functional connectivity

Online: 25 September 2023 (13:03:15 CEST)

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Preprint REVIEW | doi:10.20944/preprints202309.1598.v1

O-GlcNAcylation: The Sweet Side of Epigenetics

Thomas Dupas, Benjamin Lauzier, Serge McGraw

Subject: Biology And Life Sciences, Biochemistry And Molecular Biology Keywords: O-GlcNAcylation, epigenetics, histone modification

Online: 25 September 2023 (13:02:16 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202309.1668.v1

Multidisciplinary Approach to Primary Immunodeficiency Due to Defect in Innate Immunity: About a Case

Álvaro Astasio-Picado, Jesus Jurado Palomo, Maria Carmen Zabala Baños

Subject: Public Health And Healthcare, Public, Environmental And Occupational Health Keywords: Chronic-granulomatous disease, NADPH oxidase, human neutrophils, superoxide, immune deficiciency, recurrent infections

Online: 25 September 2023 (13:01:17 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202309.1588.v1

End-to-End Premature Ventricular Contraction Detection using Deep Neural Networks

Dimitri Kraft, Gerald Bieber, Peter Jokisch, Peter Rumm

Subject: Computer Science And Mathematics, Artificial Intelligence And Machine Learning Keywords: Ventricular Premature Contractions (PVC) detection; 1D U-Net neural network; Holter monitoring

Online: 25 September 2023 (13:00:13 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202309.1597.v1

Galectin-3 as a Prognostic Biomarker in Patients with First Acute Myocardial Infarction Without Heart Failure

Rada M. Vucic, Olivera M. Andrejic, Dragana Stokanovic, Tatjana Jevtovic Stoimenov, Lana McClements, Valentina N. Nikolic, Miodrag Sreckovic, Mirjana Veselinovic, Srdjan Aleksandric, Viseslav Popadic, Marija Zdravkovic, Milan Pavlović

Subject: Medicine And Pharmacology, Cardiac And Cardiovascular Systems Keywords: Galectin-3, acute myocardial infarction, major adverse cardiovascular events

Online: 25 September 2023 (12:58:57 CEST)

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Preprint REVIEW | doi:10.20944/preprints202309.1600.v1

Genetic Enhancement of Plastic Degrading Bacteria: The Way to a Sustainable and Healthy Environment

Kenneth Marshall

Subject: Biology And Life Sciences, Biochemistry And Molecular Biology Keywords: Plastic degrading bacteria; sustainable environment; genetic enhancement; recycling; biodegradation

Online: 25 September 2023 (12:56:55 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202309.1606.v1

Vitamin D3 Exerts Beneficial Effects on Aging Muscles through Activation of the Vitamin D Receptor (VDR)/Sirtuin (SIRT)1/3 Axis

Nurul Fatihah Talib, Zunshu Zhu, Kyoung Soo Kim

Subject: Medicine And Pharmacology, Medicine And Pharmacology Keywords: Vitamin D; Vitamin D receptor (VDR); Sirtuin; Sarcopenia; Muscle atrophy; Mitochondrial Biogenesis; Oxidative Phosphorylation (OXPHOS)

Online: 25 September 2023 (12:55:47 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202309.1633.v1

Assessing the Effectiveness of Radon Action Plans: Searching for a Systematic and Standardized Method

Meritxell Martell, Tanja Perko, Kateřina Navrátilová Rovenská, Ivana Fojtiková, Robbe Geysmans

Subject: Social Sciences, Other Keywords: radon, radon action plan, indicators, review, radiation, assessment

Online: 25 September 2023 (12:54:41 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202309.1594.v1

A Study of PI Controller Tuning Methods by IMC Guide for a Ship Central Cooling System as a MISO System

Tae-Youl Jeon, ByungGun Jung

Subject: Engineering, Marine Engineering Keywords: Ship central cooling system; MISO; IMC

Online: 25 September 2023 (12:53:43 CEST)

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Preprint REVIEW | doi:10.20944/preprints202309.1590.v1

Digital Image Correlation Technique for Laboratory Structural Tests and Applications: A Systematic Literature Review

Mohammed Abbas Mousa, Mustafasanie M Yussof, Thulfiqar Hussein, Lateef Assi, SeyedAli Ghahari

Subject: Engineering, Civil Engineering Keywords: Keywords: Digital Image Correlation; Surface displacements; Structural monitoring; Full-scale test design

Online: 25 September 2023 (12:37:28 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202309.1574.v1

Optimization of Plant-Based Medium for Growth and Viability of Lactobacillus delbrueckii ssp. bulgaricus

Philip Junior Yeboah, Abdulhakim Sharaf Eddin, Namesha Dulari Wijemanna, Leonard L Williams, Albert Krastanov, Salam A. Ibrahim

Subject: Biology And Life Sciences, Food Science And Technology Keywords: Lactobacillus bulgaricus; growth media; nitrogen source; starter culture; bacterial enumeration

Online: 25 September 2023 (12:34:21 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202309.1635.v1

Optimal Design and Performances Enhancement of a FiberOptic Displacement Sensor

Zeina Elrawashdeh, Christine Prelle, Frédéric Lamarque, Philippe Revel, Stéphane Galland

Subject: Engineering, Control And Systems Engineering Keywords: fiber-optic sensor; displacement; global optimum; measurement range; resolution; sensitivity

Online: 25 September 2023 (12:08:09 CEST)

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Preprint TECHNICAL NOTE | doi:10.20944/preprints202309.1575.v1

Study of the Calibration of Semiconductor Survey Meters Using Medical X-ray Equipment

Katsunao Suzuki, Toru Negishi, Yoh Kato, Yasuhisa Kono, Michiharu Sekimoto

Subject: Physical Sciences, Radiation And Radiography Keywords: semiconductor survey meter; calibration; medical X-ray system; calibration factor; time constant

Online: 25 September 2023 (11:44:59 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202309.1684.v1

Adaptive Learning in Agent-Based Models: An Approach for Analyzing Human Behavior in Pandemic Crowding

David Romero, Paula Escudero

Subject: Computer Science And Mathematics, Applied Mathematics Keywords: Agent-based Modeling and Simulation; Reinforcement Learning; COVID-19; Social Simulation.

Online: 25 September 2023 (11:41:53 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202309.1686.v1

Performance Comparison of Sea Cucumber Detection by the Yolov5 and DETR Approach

Xin Yuan, Shutong Fang, Ning Li, Qiansheng Ma, Ziheng Wang, Mingfeng Gao, Pingpeng Tang, Changli Yu, Yihan Wang, José-Fernán Martínez Ortega

Subject: Engineering, Marine Engineering Keywords: underwater target detection and recognition; YOLOv5; DETR; sea cucumber fishing

Online: 25 September 2023 (11:30:23 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202309.1681.v1

A Transfer Learning-Based Deep Convolutional Neural Network for Detection of Fusarium Wilt in Banana Crops

Kevin Yan, Md Kamran Chowdhury Shisher, Yin Sun

Subject: Computer Science And Mathematics, Artificial Intelligence And Machine Learning Keywords: convolutional neural network; Fusarium wilt; transfer learning; ResNet-50; banana crop

Online: 25 September 2023 (11:29:36 CEST)

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Preprint REVIEW | doi:10.20944/preprints202309.1689.v1

Compatibility between Conservation Agriculture and the System of Rice Intensification

Francesco Carnevale Zampaolo, Amir Kassam, Theodor Friedrich, Adam Parr, Norman Uphoff

Subject: Biology And Life Sciences, Agricultural Science And Agronomy Keywords: Agroecology; GHG emissions; Cropping systems; Mulch cover; Synergies.

Online: 25 September 2023 (11:28:34 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202309.1585.v1

Theoretical Assessment of Different Aviation Fuel Blends Based on Their Physical-Chemical Properties

Radu Mirea, Grigore Cican

Subject: Engineering, Energy And Fuel Technology Keywords: Jet A; sustainable aviation fuel; kerosene; fuel blends; chemical-physical analysis; FTIR

Online: 25 September 2023 (11:28:01 CEST)

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Preprint CONCEPT PAPER | doi:10.20944/preprints202309.1691.v1

Impact of Digitization on Uplifting Business Expansion

Harshith Desamsetti, Sreekanth Dekkati

Subject: Computer Science And Mathematics, Artificial Intelligence And Machine Learning Keywords: digitization; uplifting business; business growth

Online: 25 September 2023 (11:27:42 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202309.1678.v1

Orchestration of Corporate Social Responsibility in Company Law – Reframing Human Security through Education

Onyeka Kingsley Osuji, Obinna Christian Edeji

Subject: Social Sciences, Law Keywords: company law; development studies; sociology; corporate social responsibility; education; human development; human dignity

Online: 25 September 2023 (11:26:47 CEST)

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Preprint COMMUNICATION | doi:10.20944/preprints202309.1683.v1

Super Typhoon Saola (2023) over the northern part of the South China Sea – aircraft data analysis

Junyi He, Pak Wai Chan, Y.W. Chan, P. Cheung

Subject: Environmental And Earth Sciences, Atmospheric Science And Meteorology Keywords: tropical cyclone; aircraft data; turbulence; eddy dissipation rate

Online: 25 September 2023 (11:26:19 CEST)

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Preprint REVIEW | doi:10.20944/preprints202309.1680.v1

Towards BIM-based Sustainable Structural Design Optimization: A Systematic Review and Industry Perspective

Muhammad Afzal, Rita Yi Man Li, Muhammad Faisal Ayyub, Muhammad Shoaib, Muhammad Bilal

Subject: Engineering, Architecture, Building And Construction Keywords: automated structural design; Building Information Modeling (BIM); design automation; generative design; interoperability; Structural Design Optimization (SDO); systematic framework

Online: 25 September 2023 (11:25:42 CEST)

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Structural design optimization (SDO) plays a pivotal role in enhancing various aspects of construction projects, including design quality, cost-efficiency, safety, and structural reliability. Recent endeavors in academia and industry have sought to harness the potential of Building Information Modeling (BIM) and optimization algorithms to optimize SDO and improve design outcomes. This review paper aims to synthesize these efforts, shedding light on how SDO contributes to project coordination. Furthermore, the integration of sustainability considerations and the application of innovative technologies and optimization algorithms in SDO necessitate more interactive early-stage collaboration among project stakeholders. This study offers a comprehensive exploration of contemporary research in integrated SDO employing BIM and optimization algorithms. It commences with an exploratory investigation, employing both qualitative and quantitative analysis techniques following the PRISMA systematic review methodology. Subsequently, an open-ended opinion survey was conducted among construction industry professionals in Europe. This survey yields valuable insights into the coordination challenges and potential solutions arising from technological shifts and interoperability concerns associated with widespread SDO implementation. These preliminary steps of systematic review and industry survey furnish a robust knowledge foundation, enabling the proposal of an intelligent framework for automating early-stage sustainable structural design optimization (ESSDO) within the construction sector. The framework ESSDO addresses the challenges of fragmented collaboration between architects and structural engineers. This proposed framework seamlessly integrates with the BIM platform, i.e., Autodesk Revit for architects. It extracts crucial architectural data and transfers it to the structural design and analysis platform, i.e., Autodesk Robot Structural Analysis (RSA), for structural engineers via the visual programming tool Dynamo. Once the optimization occurs, optimal outcomes are visualized within BIM environments. This visualization elevates interactive collaborations between architects and engineers, facilitating automation throughout the workflow and smoother information exchange.

Preprint ARTICLE | doi:10.20944/preprints202309.1687.v1

Virulence of Circulating Marek’s Disease Virus Strains in Vaccinated Chicken Flocks in Taiwan: Data on Genetic Analysis of the meq Oncogene

Ming-Chu Cheng, Guan-Hua Lai, Yi-Lun Tsai, Yi-Yang Lien

Subject: Biology And Life Sciences, Animal Science, Veterinary Science And Zoology Keywords: Marek’s disease virus; vaccinated chicken flocks; meq oncogene; genetic characteristics; virulence

Online: 25 September 2023 (11:24:28 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202309.1666.v1

TFR: Texture Defect Detection with Fourier Transform Using Normal Reconstructed Template of Simple Autoencoder

Jongwook Si, Sungyoung Kim

Subject: Computer Science And Mathematics, Computer Science Keywords: texture; defect detection; anomaly detection; Fourier transform; reconstruction

Online: 25 September 2023 (11:23:30 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202309.1667.v1

A Practical Approach for Real-Time DOV Compensation in an Embedded Computer of an INS Using Multi-Layer Perceptron

Hyunseok Kim, Hyungsoo Kim, Yunhyuk Choi, Yunchul Cho, Chansik Park

Subject: Engineering, Aerospace Engineering Keywords: inertial navigation system (INS); earth gravity model (EGM); deflection of vertical (DOV); multi-layer perceptron (MLP)

Online: 25 September 2023 (11:22:21 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202309.1662.v1

The Objective is to Enhance Sales through an Offline to Online (O2O) Strategy (Case Study: Kampoeng Merdeka Clothing in Makassar City)

Imaduddin Murdifin

Subject: Business, Economics And Management, Marketing Keywords: Online to Offline (O2O) transition strategy; transaction security; sales volume; O2O networks

Online: 25 September 2023 (11:13:48 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202309.1673.v1

Study on the Rainwater Interception Process and Capacity of Urban Tree Organs in Shanghai

Benyao Wang, Yanting Zhang, Jiankang Guo

Subject: Environmental And Earth Sciences, Ecology Keywords: tree organs; urban tree species; rainwater interception capacity; Shanghai

Online: 25 September 2023 (11:09:25 CEST)

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Preprint REVIEW | doi:10.20944/preprints202309.1677.v1

Application and Development Prospects of Phosphogypsum in Different Phases: A Review

Li Ma, Huali Zhang, Xiaofeng Wang, Luyu Chen

Subject: Environmental And Earth Sciences, Waste Management And Disposal Keywords: solid waste; phosphogypsum phases; crystal morphology; mechanical properties; comprehensive utilization

Online: 25 September 2023 (11:07:20 CEST)

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Preprint REVIEW | doi:10.20944/preprints202309.1651.v1

Insulin Resistance Develops Due to an Imbalance in the Synthesis of Cyclic AMP and the Natural Cyclic AMP Antagonist Prostaglandyl-Inositol Cyclic Phosphate (Cyclic PIP)

Heinrich K Wasner

Subject: Biology And Life Sciences, Endocrinology And Metabolism Keywords: cyclic AMP; cyclic PIP; insulin resistance; prostaglandylinositol cyclic phosphate; protein phosphorylation; protein kinase A; protein ser/thr phosphatase; type 2 diabetes

Online: 25 September 2023 (11:05:29 CEST)

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Dear Ladies and Gentlemen, I thank you for suggesting to submit the manuscript with the title “Insulin resistance develops due to an imbalance in the synthesis of cyclic AMP and the natural cyclic AMP antagonist prostaglandylinositol cyclic phosphate (cyclic PIP)” to the Editorial Board of the MDPI journal Stresses, and I ask for consideration to publish it in the journal Stresses. It was previously submitted to the MDPI journal Int. J. Mol. Sci. (IJMS-195 6513), but it was found that 1) it would not fit within the scope of this special edition and 2) it would primarily deal with cyclic PIP and would have not enough literature citation on the topic insulin resistance. The present version of the manuscript is improved, but the content is the same. The goal of this review is not to write again a summary on nearly all reports on insulin resistance as this was done by Dr. Petersen and Dr. Shulman, whose review has 961 literature citations. The present manuscript compiles what is known on cyclic PIP in relation to insulin resistance and the reason of writing this manuscript was that the discovered facts on cyclic PIP synthesis allow to suggest how insulin resistance most likely starts. Hitherto, reports on insulin resistance did not come close to this question. I am convinced that the manuscript makes an essential contribution to the question what causes the development of insulin resistance, and I have to say that stress overload is one of the reasons. Unfortunately, I have to mention a topic, about which I do not like to talk. Years ago, research groups postulated with rigor that the mediator of insulin action would be a peptide and then they suggested various, extracellularly synthesized glycans as mediators. They caused confusions and a high degree of disbelief in the matter of mediators of insulin action. In my review on cyclic PIP in IUBMB Life from 2020, I wrote in the introduction that cyclic PIP should not be confused with these mediators. But I cannot write this in the introduction of every report. I am keeping fingers crossed so that the editor in charge will find fair and openminded reviewers. Last not least I confirm that neither the manuscript nor any part of its content is currently under consideration or published in another journal. Kind regards, Henrich Wasner, PhD, BioReg Biopharm, TiLab; University of Illinois at Chicago; 2242 West Harrison St., Ste. 201, Chicago, Il 60612; USA

Preprint COMMUNICATION | doi:10.20944/preprints202309.0984.v2

Simulation and Analysis of Cyber-Attack on Modbus Protocol for Smart Grids in Virtual Environment

Trapa Banik, Rajesh Manicavasagam, Shampa Banik, Shudipta Banik

Subject: Computer Science And Mathematics, Computer Networks And Communications Keywords: smart grid (SG); communication protocols; Modbus; virtual testbed; cyber-attacks; and security vulnerabilities

Online: 25 September 2023 (11:04:26 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202309.1646.v1

Investigating Asphaltene Deposition Kinetics through Particle Size and Count Correlation

Muhammad Ali, Alake Adedamola Stephen

Subject: Chemistry And Materials Science, Physical Chemistry Keywords: Asphaltene kinetics, aggregate kinetics, precipitation kinetics

Online: 25 September 2023 (11:03:08 CEST)

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Asphaltene precipitation and deposition pose significant operational challenges in both reservoirs and surface facilities by inducing formation damage. To understand the kinetics involved in asphaltene particle nucleation, growth, and aggregation, this study employed confocal microscopy and centrifuge-based methods under a unified set of experimental parameters. The acquired time-resolved particle size images were analyzed using MIPAR image processing software, while asphaltene mass yield was quantitatively evaluated through centrifugation. Experimental conditions were varied to study the effects of heptane concentration, asphaltene concentration, and shear rate. Notably, this investigation introduces, for the first time, the parameter of particle count as an additional variable influencing asphaltene mass production. This study aims to discern how particle count correlates with asphaltene mass yield over time. Results indicate that the minimum mean particle diameter was observed to be 2 microns, which progressively grew up to 80 microns. The mean particle diameter exhibited a positive correlation with both asphaltene concentration and shear rate, whereas an inverse correlation was seen with heptane concentration. Furthermore, the asphaltene mass yield was found to increase with greater asphaltene and heptane concentrations, as well as with higher shear rates. The relationship between mean particle diameter and mass yield was found to be nonlinear. In the early stages, a higher prevalence of small particles contributed to a greater total particle count, while at later stages, particle aggregation led to the formation of larger particles that influenced the overall asphaltene mass. The insights gained from understanding the relationship between particle diameter, count, and mass yield are crucial for advancing the fundamental science of asphaltene precipitation and deposition. These findings may also guide future research that relies solely on particle counts for assessing asphaltene deposition.

Preprint ARTICLE | doi:10.20944/preprints202309.1679.v1

Explaining the Ratios of Masses of all Three Generations of Leptons and Quarks and Predicting the Mass Eigenstates of Neutrinos

Nikola Perkovic

Subject: Physical Sciences, Particle And Field Physics Keywords: higgs mechanism; yukawa coupling; fine structure constant; leptons, quarks

Online: 25 September 2023 (11:02:52 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202309.1672.v1

Mitigation of Salmonella in Ground Pork Products through Gland Removal in Pork Trimmings

Reagan L. Jimenez, Mindy M Brashears, Rossy Bueno López, David A. Vargas, Marcos X. Sanchez-Plata

Subject: Biology And Life Sciences, Food Science And Technology Keywords: lymph node; risk assessment; quantification

Online: 25 September 2023 (11:02:19 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202309.1649.v1

Limbic System Response to Psilocybin and Ketamine Administration in Rats: A Neurochemical and Behavioral Study

Adam Wojtas, Agnieszka Bysiek, Agnieszka Wawrzczak-Bargiela, Marzena Maćkowiak, Krystyna Gołembiowska

Subject: Medicine And Pharmacology, Neuroscience And Neurology Keywords: neurotransmitter release; dopamine D2 receptors; serotonin 5-HT1A; 5-HT2A receptors; limbic system

Online: 25 September 2023 (10:46:59 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202309.1661.v1

Relationship between the Silk Road and Circumglobal Teleconnection Patterns on the Interannual and Interdecadal Timescales

Yong Liu

Subject: Environmental And Earth Sciences, Atmospheric Science And Meteorology Keywords: Silk Road pattern; circumglobal teleconnection pattern; linkages and differences; interannual and interdecadal timescales

Online: 25 September 2023 (10:42:37 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202309.1629.v1

Improving the Biogas Production and Methane Yield in an UASB Reactor with the Addition of Sulfate

Dimitra Theodosi Palimeri, Konstantina Papadopoulou, Apostolos G. Vlyssides, Anestis A. Vlysidis

Subject: Environmental And Earth Sciences, Waste Management And Disposal Keywords: anaerobic digestion; UASB reactor; COD/SO4-2 ratio; Methane production; Microbial diversity; sulfate reduction; sulfate-rich substrate

Online: 25 September 2023 (10:37:27 CEST)

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Preprint REVIEW | doi:10.20944/preprints202309.1654.v1

Recent advance and Prospect of Enhanced Oil Recovery Mech-anisms in Reservoir Sandstone

Surajudeen Sikiru, Hassan Soleimani, Jemilat Yetunde Yusuf, Yarima Mudassir Hassan, Mohammed Falalu Hamza, Ramesh Singh

Subject: Engineering, Energy And Fuel Technology Keywords: enhanced oil recovery; rock permeability; reservoir fluid; porosity; fluid flow

Online: 25 September 2023 (10:32:37 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202309.1674.v1

Reducing Carbon Footprint with Precipitated Calcium Carbonate (PCC) in Geotechnical Applications

Kabiraj Phuyal, Ujwal Sharma, James Mahar, Kunal Mondal, Mustafa Mashal

Subject: Engineering, Civil Engineering Keywords: Soil Stabilization; Precipitated Calcium Carbonate (PCC); Energy Dispersive X-ray Spectrometer (EDX); Collapsible Soil

Online: 25 September 2023 (10:27:21 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202309.1628.v1

Exploring the Marginal Effects of Climate Change on Farming System Choice: A Farm-Level Space-for-Time Approach

Paulo Flores Ribeiro, José Lima Santos

Subject: Biology And Life Sciences, Agricultural Science And Agronomy Keywords: climate change; farming systems; space-for-time; marginal effect; choice modelling

Online: 25 September 2023 (10:25:13 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202309.1639.v1

Effects of Quenching Temperature on the Microstructure and Mechanical Properties of a Medium-Mn Steel Processed by Quenching and Partitioning

Cansheng Yu, Hesong Wang, Yuanxiang Zhang, Yunjie Li, Jian Kang, Zhiyuan Chang

Subject: Engineering, Metallurgy And Metallurgical Engineering Keywords: medium-Mn steel; twin-roll strip casting; quenching and partitioning; microstructure; mechanical properties

Online: 25 September 2023 (10:15:17 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202309.1676.v1

Varietal Differences in the Root Systems of Rice (Oryza sativa L.) under Drip Irrigation with Plastic-Film Mulch

JUNFA WANG, Oluwasegun Olamide Fawibe, Akihiro Isoda

Subject: Biology And Life Sciences, Agricultural Science And Agronomy Keywords: drip irrigation; root; varietal difference; deep root; plastic-film mulch

Online: 25 September 2023 (10:13:49 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202309.1605.v1

A Comparative Study of Equine Hoof Progenitor Cells and Adipose-Derived Stem Cells in Hyperinsulinemia

Ariadna Pielok, Jarosław Króliczewski, Martyna Kępska, Krzysztof Marycz

Subject: Biology And Life Sciences, Biochemistry And Molecular Biology Keywords: equine metabolic syndrome; hyperinsulinemia; miRNA; mitochondrial metabolism; laminitis; stem cells; HPC; ASC; hoof

Online: 25 September 2023 (10:12:43 CEST)

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Recently, we isolated and characterized a new pool of mesenchymal stem cells- HPC (Hoof Progenitor Cells), which reside in the coronary corium of equine hooves. We hypothesize, that due to their location, HPC may be involved in the pathogenesis of laminitis, and could possibly be utilized in its treatment. The aim of this study was to compare the newly described HPC to a well-established cell pool-ASC (Adipose Stem Cells). The two cell populations were maintained either in standard culture conditions or under a hyperinsulinemic milieu as hyperinsulinemia is often observed alongside laminitis. Cell cycle dynamics, mitochondrial membrane potential and oxidative stress were analyzed with microcapillary cytometry. Furthermore, the expression of key markers of mitochondrial metabolism, oxidative stress, apoptosis, immunomodulation and insulin signalling were analyzed with the RT-qPCR method. Additionally, a selected panel of miRNA was analyzed with the RT-qPCR method. In standard culture conditions, ASC exhibit higher proliferation than HPC while in hyperinsulinemia a shift towards S phase was observed in both populations. As for the mitochondrial membrane potential, in standard culture conditions, HPC was characterized by a higher percent of live cells. Hyperinsulinemia did not strongly affect the mitochondrial membrane potential of the analyzed populations. Our findings indicate that HPC are characterized by higher activity in terms of mitochondrial dynamics, mitophagy, and mitochondrial biogenesis under standard culture conditions. Yet in both populations, a diminished mitochondrial dynamic and metabolism was observed in hyperinsulinemia. The analysis of oxidative stress revealed, that HPC might possess somewhat higher resistance towards oxidative stress than ASC. Minimal change was observed in the expression of key markers of apoptosis in ASC and HPC under hyperinsulinemia. The analysis of key immunomodulatory markers indicated that HPC may help the cytokine storm for a more effective phenotype change to an immunosuppressing pool of cells with better migratory and healing abilities under hyperinsulinemia than ASC. As for insulin signalling, the obtained data suggests that HPC might be more resistant to hyperinsulinemia and may have greater therapeutic potential in reducing laminitis. Obtained results demonstrated that HPC possesses better potential to modulate the PTEN-AKT pathway by miR-21 and reverse high glucose and high insulin-induced insulin resistance. Taken together, the obtained results indicate that HPC may be a very promising cell pool with therapeutic potential in laminitis treatment, and could be more effective than ASC.

Preprint ARTICLE | doi:10.20944/preprints202309.1601.v1

Validation of FY-4A/AGRI LST and High Temporal-spatial Resolution Analysis of Surface Heat Resources in Hunan Province, Central China

Jiazhi Fan, Hao Lin, Qinzhe Han, Leishi Chen, Shiqi Tan, Wei Li

Subject: Environmental And Earth Sciences, Environmental Science Keywords: FY-4A/AGRI LST; In situ measurement; remote sensing product evaluation; surface heat resource; temporal and spatial analysis

Online: 25 September 2023 (10:09:45 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202309.1675.v1

Dataset and System Design for Orthopedic Walker Fall Detection and Activity Logging Using Motion Classification

Antony Garcia, Maxwell Huang

Subject: Engineering, Electrical And Electronic Engineering Keywords: orthopedic walker; dataset; IoT; fall detection; activity logging; inertial measurement unit; machine learning; deep learning

Online: 25 September 2023 (10:07:40 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202309.1592.v1

Effect of Different Local Vibration Durations on Knee Extensors’ Maximal Isometric Strength

Nicolas Amiez, Stella Zwgrafou, Tom Timbert, Alain Martin, Spyridon Methenitis, Nicolas Babault, Christos Paizis

Subject: Biology And Life Sciences, Anatomy And Physiology Keywords: local vibration; maximal voluntary isometric strength; knee extensor

Online: 25 September 2023 (10:06:57 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202309.1652.v1

The Impact of the COVID-19 Pandemic on Depressive Disorder with Postpartum Onset

Livia Ciolac, Marius Lucian Craina, Virgil Radu Enatescu, Anca Tudor, Elena S Bernad, Razvan Nitu, Lavinia Hogea, Lioara Boscu, Brenda-Cristiana Bernad, Madalina Otilia Timircan, Cristian Octavian Nediglea, Anca Laura Maghiari

Subject: Medicine And Pharmacology, Obstetrics And Gynaecology Keywords: Postpartum depression; Screening; Pandemic; COVID-19; Edinburgh Postnatal Depression Rating Scale (EPDS)

Online: 25 September 2023 (10:04:31 CEST)

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Background: The potential impact of the pandemic on mental health should not be overlooked, especially among vulnerable populations such as women who gave birth during the COVID-19 pandemic. The aim of the study was to assess the mental health status of women who gave birth during a pandemic and to examine the possible links between the onset of depressive disorder symptoms in close proximity to the time of delivery and the socio-demographic conditions, health status and obstetric circumstances of the patients. Materials and Methods: The study is a cross-sectional survey conducted from 01.03.2020 to 01.03.2023, during the period of SARS-CoV-2 (COVID-19) pandemic, based on a retrospective evaluation of 860 postpartum women. The screening tool used to assess symptoms of postpartum depression was the Edinburgh Postnatal Depression Rating Scale (EPDS) questionnaire. The questionnaire was completed both in the Obstetrics and Gynaecology Clinical Sections I and II of the "Pius Brînzeu" County Emergency Hospital from Timisoara, Romania and online using Google Forms. Results: The highest severity of postpartum depression symptoms was observed during the COVID-19 pandemic. The results of the study conducted during the period of SARS-CoV-2 pandemic (COVID-19) showed that the prevalence of major postpartum depressive disorder (EPDS ≥ 13) was 54.2% (466 patients), while 15.6% (134) had minor depressive disorder (10 < EPDS ≤ 12) in the first year after delivery. Comparing these results with those obtained in research conducted before the onset of the pandemic period shows an alarming increase in the prevalence of postpartum depression. Risk factors associated with postpartum depression included type of delivery, level of education, socio-economic conditions, health status, age, background, personal obstetric history (number of abortions on demand, parity). Conclusions: The effects of the pandemic on mental health are of particular concern for women in the first year after childbirth. Observing these challenges and developing effective measures to prepare our health system early can help and facilitate effective mental health screening for postpartum women, promoting maternal and child health.

Preprint ARTICLE | doi:10.20944/preprints202309.1596.v1

Exploring Machine Learning Techniques to Maximize Efficiency in Construction Industry Electrical and Electronics Engineering Projects

Nwosu Obinnaya Chikezie Victor

Subject: Engineering, Electrical And Electronic Engineering Keywords: machine learning; construction industry; electrical engineering; electronics engineering

Online: 25 September 2023 (09:55:05 CEST)

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The construction enterprise is a essential zone that contributes considerably to the worldwide financial system. but it faces numerous challenges, together with inefficiency in electric and electronics engineering tasks. This inefficiency results in delays, expanded charges, and decreased productivity. Device learning strategies have the capacity to deal with those challenges through optimizing the making plans and execution of electrical and electronics engineering tasks within the construction industry. This study paper targets to discover using machines gaining knowledge of strategies to maximise efficiency in electrical and electronics engineering projects inside the production industry. Mainly, the paper will be conscious of developing and imposing gadget mastering algorithms to optimize project scheduling, fabric procurement, and system utilization. The paper will even look at the ability of using predictive analytics to identify and mitigate dangers related to electric and electronics engineering tasks. The study could be based on a combination of literature review and empirical analysis. The literature evaluation will provide a top-level view of the demanding situations going through the development industry and the capability advantages of the usage of system getting to know strategies to deal with those challenges. The empirical evaluation will involve the improvement and testing of device mastering models on real-world information from electrical and electronics engineering initiatives inside the construction industry. The predicted results of this research are the development of a fixed of sensible recommendations for the use of machine gaining knowledge of strategies to optimize electric and electronics engineering projects within the construction industry. These suggestions will be beneficial for venture managers, engineers, and other stakeholders within the creation enterprise who're inquisitive about maximizing performance and decreasing charges of their tasks. Ordinary, this studies paper aims to contribute to the continued efforts to enhance the efficiency and productiveness of the development enterprise via exploring the ability of system studying techniques to optimize electrical and electronics engineering tasks.

Preprint ARTICLE | doi:10.20944/preprints202309.1617.v1

Burnout and its Relationship with Work Engagement in Healthcare Professionals: A Latent Profile Analysis Approach

Juan José Luis Sienra-Monge, David Luna, Rosa Paola Figuerola-Escoto, Alejandra Hernández-Roque, Arturo Soria-Magaña, Sandra Hernández-Corral, Filiberto Toledano-Toledano

Subject: Social Sciences, Psychology Keywords: nurses; México; logistic regression; predictors; mental health; Spanish burnout inventory

Online: 25 September 2023 (09:48:40 CEST)

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Preprint REVIEW | doi:10.20944/preprints202309.1593.v1

Taxanes in the Treatment of Head and Neck Squamous Cell Carcinoma

Ching-Yun Hsieh, Ching-Chan Lin, Wei-chao Chang

Subject: Biology And Life Sciences, Biochemistry And Molecular Biology Keywords: head and neck squamous cell carcinoma (HNSCC); taxanes; docetaxel (DTX); resistance

Online: 25 September 2023 (09:40:28 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202309.1670.v1

Cloud-Based Machine Learning for Flood Policy Recommendation in Makassar City, Indonesia

Andi Besse Rimba, Andi Arumansawang, I Putu Wira Utama, Saroj Kumar Chapagain, Made Nia Bunga, Geetha Mohan, Kuncoro Teguh Setiawan, Takahiro Osawa

Subject: Environmental And Earth Sciences, Water Science And Technology Keywords: Flood detection; Satellite imagery; drainage; urban land use plan; land cover; slope; elevation

Online: 25 September 2023 (09:38:47 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202309.1665.v1

Generalized Rash in Severe Hospitalized COVID Patients: Correlation between Histological Examination, Drug Intake, Blood Interleukins Profileand Long-Term Follow-Up

Montserrat Fernández-Guarino, Vivian Stewart, Diego Fernández-Nieto, Carmen Moreno Garcia del Real, David Gonzalez de Olano, Carolina Blanco, Emilio Solano-Solares, Belen De la Hoz Caballer, Javier Martínez-Botas, Maria Laura Garcia-Bermejo, Ana Andrés-Martín

Subject: Medicine And Pharmacology, Dermatology Keywords: skin; COVID infection; cytokines; SARS-CoV-2

Online: 25 September 2023 (09:37:37 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202309.1663.v1

Chemical Constituents of the Deep-Sea-Derived Penicillium citrinum W17 and Their Anti-Inflammatory and Anti-Osteoporotic Bioactivities

Yong Zhang, Chun-Lan Xie, Yuan Wang, Xi-Wen He, Ming-Min Xie, You Li, Kai Zhang, Zheng-Biao Zou, Long-He Yang, Xian-Wen Yang, Ren Xu

Subject: Chemistry And Materials Science, Medicinal Chemistry Keywords: deep-sea; fungus; Penicillium citrinum; polyketides; anti-osteoporosis; anti-inflammation.

Online: 25 September 2023 (09:36:29 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202303.0540.v3

Sixteen Pairs of 4-Component Spinors for SL(4,C) and Four Types of Transformations with a Conjugate Space Which Has No Counterpart in SL(2,C)

Mehmet Ali Kuntman

Subject: Physical Sciences, Theoretical Physics Keywords: Lie Algebra; Lorentz group; SL(4,C); particle physics; polarization optics; nanoparticle interactions

Online: 25 September 2023 (09:34:12 CEST)

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Preprint COMMUNICATION | doi:10.20944/preprints202309.1634.v1

Super Typhoon Saola (2309) affecting Hong Kong in September 2023–Forecasting Aspect

P.W. Chan, Y.H. He, Y.S. Lui

Subject: Environmental And Earth Sciences, Atmospheric Science And Meteorology Keywords: tropical cyclone; track; intensity; wind structure

Online: 25 September 2023 (09:32:43 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202309.1650.v1

Nonlinear Finite Element Analysis and Fatigue Damage Assessment of Wind-Induced Vibration for the Tension Cable-Supported Power Transmission Structure

Jingyang Li, Bangjie Wang, Tao Wang, Zhengliang Li

Subject: Engineering, Civil Engineering Keywords: Tension cable-supported power transmission structure; Wind-induced vibration; Nonlinear finite element; Wind-induced fatigue damage

Online: 25 September 2023 (09:32:35 CEST)

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The tension cable-supported power transmission structure (TC-PTS) is a new type of power transmission structure suitable for mountainous terrain, which is sensitive to wind load. In this regard, a nonlinear finite element analysis model of wind-induced vibration is proposed for the TC-PTS, and the wind-induced vibration response of the structure is analyzed. Firstly, the tangent stiffness matrix of the three-dimensional truss element for the supporting suspension cable and transmission line, considering the geometric nonlinearity of structures, is derived through the relationship between the element elastic energy and its displacement. Subsequently, the element mass matrix and damping matrix of the supporting suspension cable and transmission line, as well as the element nodal load vector obtained from wind load equivalence are given. Then, based on the nonlinear finite element theory, the nonlinear dynamic equation of wind-induced vibration is established for the TC-PTS and solved by Newmark-β method combined with Newton-Raphson iterative method. Furthermore, the rain-flow counting method and Miner's linear fatigue cumulative damage theory were used for wind induced fatigue damage assessment. Finally, a two-span TC-PTS is selected as an example, and the wind-induced nonlinear vibration and fatigue damage assessment are analyzed through the proposed model. The results show that the proposed model has high computational accuracy and efficiency. With the increase of wind speed and wind direction angle, the maximum lateral displacement and tension of the supporting suspension cable and transmission line increase, and their degree of increase shows a nonlinear trend. In terms of the wind-induced fatigue analysis results of TC-PTS, the fatigue damage at the end of the supporting-conductor suspension cable is greater than the fatigue damage at its midpoint. Compared to the fatigue damage at the midpoint of the conductor, the fatigue damage at the end of the conductor is less affected by wind direction angle, and both are more significantly affected by the wind speed.

Preprint ARTICLE | doi:10.20944/preprints202309.1648.v1

DL-3-Aminobutyric Acid and Powdery Mildew Infection Enhanced the Activation of Defense Related Genes and Salicylic Acid in Cucumber (Cucumis sativus L.)

Hee-Wan Kang, Ja-yoon Kim

Subject: Biology And Life Sciences, Horticulture Keywords: cucumber; powdery mildew; infection; DL-3-amino-butyric acid; defense gene

Online: 25 September 2023 (09:31:29 CEST)

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Preprint REVIEW | doi:10.20944/preprints202309.1642.v1

The Shrinking and Expanding Eastern Africa Rift Valley Lakes: The Case of Ethiopian and Kenyan Rift Valley Lakes: Review

Gizaw Abera Abera Gebreegziabher, Sileshi Degefa, Wakgari Furi

Subject: Environmental And Earth Sciences, Environmental Science Keywords: east Africa rift; size of lakes; lake expansion; shrinking of lakes

Online: 25 September 2023 (09:29:23 CEST)

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Preprint REVIEW | doi:10.20944/preprints202309.1647.v1

Cholinergic Polarization of Human Macrophages

Natalia Roa-Vidal, Adriana S Rodriguez-Aponte, José Antonio Lasalde-Dominicci, Coral M Capó-Vélez, Manuel Delgado-Vélez

Subject: Biology And Life Sciences, Immunology And Microbiology Keywords: macrophage; inflammation; acetylcholine receptor; cholinergic receptor; polarization, cholinergic agonist; alpha 7 nicotinic acetylcholine receptor; CHRFAM7A, cholinergic machinery, cholinergic anti-inflammatory pathway

Online: 25 September 2023 (09:28:51 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202309.1638.v1

Antidiabetic Therapy during Pregnancy: The Prescription Pattern in Italy

Anna Locatelli, Sara Ornaghi, Alessandra Terzaghi, Valeria Belleudi, Filomena Fortinguerra, Francesca Romana Poggi, Serena Perna, Francesco Trotta

Subject: Medicine And Pharmacology, Obstetrics And Gynaecology Keywords: Gestational Diabetes Mellitus; pregnancy; antidiabetic drugs; prescription pattern

Online: 25 September 2023 (09:27:25 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202309.1653.v1

The p53 tumor suppressor protein activates transcription of DUSP13 isoform from the alternative promoter in intron 3

Małgorzata Krześniak, Barbara Łasut-Szyszka, Agnieszka Będzińska, Agnieszka Gdowicz-Kłosok, Marek Rusin

Subject: Biology And Life Sciences, Biochemistry And Molecular Biology Keywords: p53; MDM2; DUSP13; alternative promoter; dual-specificity phosphatase

Online: 25 September 2023 (09:21:39 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202309.1637.v1

Constraining Flood Forecasting Uncertainties through Streamflow Data Assimilation in the Tropical Andes of Peru: Case of the Vilcanota River Basin

Harold Llauca, Miguel Arestegui, Waldo Lavado-Casimiro

Subject: Environmental And Earth Sciences, Water Science And Technology Keywords: Streamflow Data Assimilation; Flood forecasting; Tropical Andes; Satellite Precipitation Products; GR4H model

Online: 25 September 2023 (09:00:46 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202309.1669.v1

Harmonization in atmospheric dispersion modelling approaches to assess toxic consequences in the neighbourhood of industrial facilities

Jean-Marc LACOME, Guillaume LEROY, Lauris JOUBERT, Benjamin TRUCHOT

Subject: Environmental And Earth Sciences, Atmospheric Science And Meteorology Keywords: atmospheric dispersion models; atmospheric dispersion of pollutants; toxic release; regulatory purposes; emergency response

Online: 25 September 2023 (08:45:13 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202309.1623.v1

Refined Equivalent Modeling Method for Mixed Wind Farms Based on Small Sample Data

Qianlong Zhu, Wenjing Xiong, Haijiao Wang, Xiaoqiang Jin

Subject: Engineering, Electrical And Electronic Engineering Keywords: Mixed wind farm; refined equivalent modeling; artificial intelligence technology; small sample data; equivalent node model

Online: 25 September 2023 (08:32:04 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202309.1660.v1

Decreasing access to water and coping strategies to shortage in informal settlements of Calabar, Nigeria.

Julius Uti Nchor, Leonard Edadi Ukam

Subject: Environmental And Earth Sciences, Water Science And Technology Keywords: water; water accessibility; water system; resilient; coping strategies; households.

Online: 25 September 2023 (08:15:25 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202309.1463.v1

The Structural Properties of (2,6)-Fullerenes

Rui Yang, Mingzhu Yuan

Subject: Computer Science And Mathematics, Discrete Mathematics And Combinatorics Keywords: (2,6)-fullerene; edge-connectivity; anti-Kekule number; resonance; perfect matching

Online: 25 September 2023 (08:05:56 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202309.1657.v1

Palliative Care In Portugal - From Intention To Reality, What is Yet to Be Accomplished

Paulo Marques, Francisca Rêgo, Rui Nunes

Subject: Public Health And Healthcare, Nursing Keywords: palliative care; health policy; health knowledge; education; organizational efficiency.

Online: 25 September 2023 (07:50:39 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202309.1631.v1

Effect of Film Thickness on Microstructural and Magnetic Properties of Lithium Ferrite Films Prepared on SrTiO₃ (001) Substrates

Kun Liu, Ruyi Zhang, Lu Lu, Jiankang Li, Songyou Zhang

Subject: Chemistry And Materials Science, Electronic, Optical And Magnetic Materials Keywords: Lithium ferrite; film thickness; defects; magnetic properties; electron microscopy

Online: 25 September 2023 (07:28:24 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202309.1610.v1

Interactions of Metal Ions with Fulvic Acids: Particle Size Distribution, Colloidal Stability and Thermodynamic Aspects

Martina Klučáková, Jitka Krouská, Michal Kalina

Subject: Environmental And Earth Sciences, Soil Science Keywords: fulvic acid; metal ion; interaction; thermodynamics; particle size; charge

Online: 25 September 2023 (07:27:00 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202309.1630.v1

Sperm Chromatin Status and DNA Fragmentation in Mouse Species with Diverging Mating Systems

Clara Agudo-Rios, Ana Sanchez-Rodriguez, Ingrid I. D. Idrovo, Juan Ángel Laborda-Gomariz, Ana Josefa Soler, Maria E. Teves, Eduardo R. S. Roldan

Subject: Biology And Life Sciences, Cell And Developmental Biology Keywords: chromatin compaction; chromomycin A3, aniline; diff-quik; DNA fragmentation; SCSA

Online: 25 September 2023 (07:06:55 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202309.0329.v2

Exploring the Use of the AEDET Hospital Evaluation Toolkit to Create a Better Healing Environment for Cancer Patients Beyond the Global North

Bedia Tekbiyik Tekin, Ozgur Dincyurek

Subject: Arts And Humanities, Architecture Keywords: hospitals; Environmental design; environmental comfort; healing environment; patient-centred care; evidence-based design; architectural space quality; health and wellbeing outcomes

Online: 25 September 2023 (07:05:33 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202309.1644.v1

Strength and Stiffness Evaluation of Fiber Reinforced Cement Stabilized Fly Ash-Stone Dust-Aggregate Mixture

Sanjeeb Kumar Mohanty, Dipti Ranjan Biswal, Benu Gopal Mohapatra, Brundaban Beriha, Ramachandra Pradhan, Harekrushna Sutar

Subject: Chemistry And Materials Science, Ceramics And Composites Keywords: fly ash; fiber reinforcement; cement stabilization; compressive strength; indirect tensile strength; flexural strength; resilient modulus; subbase and base.

Online: 25 September 2023 (06:36:19 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202309.1534.v1

Thermoreversible Gelation with Supramolecularly Polymerized Cross-Link Junctions

Fumihiko Tanaka

Subject: Chemistry And Materials Science, Polymers And Plastics Keywords: thermoreversible gelation; supramolecular cross-linking; cooperative polymerization; Bose--Einstein condensation of rings; metal-coordinated supramolecules; ladder junction / egg-box junction

Online: 25 September 2023 (06:19:34 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202309.1640.v1

Does Regulated Deficit Irrigation Affect Pear Fruit Texture by Modifying the Stone Cells?

Jesús D. Peco, Hava F Rapoport, Ana Centeno, David Pérez-López

Subject: Biology And Life Sciences, Anatomy And Physiology Keywords: Pyrus communis; pear; regulated deficit irrigation; stone cells; fruit quality

Online: 25 September 2023 (06:16:57 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202309.1581.v1

Isolation and Characterization of a Viable Toxoplasma gondii From Captive Caracal (Caracal caracal)

Hongjie Ren, Gaohui Mao, Yan Zhang, Niuping Zhu, Qunchao Liang, Yibao Jiang, Yurong Yang

Subject: Biology And Life Sciences, Parasitology Keywords: toxoplasma gondii; caracal (Caracal caracal); virulence; ToxoDB#5; transmission

Online: 25 September 2023 (06:10:25 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202309.1611.v1

Effects of Lotus (Nelumbo nucifera Gaertn.) on the Methane Emission in Littoral Zones of a Subtropical Lake, China

Wenchang Zhou, Xiangjuan Yuan, Liangkang He, Yuhu Shi, Xiuhuan Xu, Wenhui Ou, Shanshan Xiang, Jiawei Yang, Tian Fu

Subject: Environmental And Earth Sciences, Ecology Keywords: methane emission; littoral lake; lotus; carbon sink; greenhouse gases; Yangtze River

Online: 25 September 2023 (06:04:52 CEST)

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