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Preprint REVIEW | doi:10.20944/preprints202309.1545.v1

Why Do We Need Alternative Methods for Fungal Disease Management in Plants?

Michael S McLaughlin, Maria Roy, Pervaiz A. Abbasi, Odile Carisse, Svetlana Yurgel, Shawkat Ali

Subject: Agricultural Science And Agronomy, Biology And Life Sciences Keywords: alternative methods; fungal disease management; plants; alternative methods; fungal disease management; plants

Online: 22 September 2023 (09:22:05 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202309.1524.v1

Structural and Spectroscopic Study on La(III) Complex of 1,2,3-Triazole Ligand with Antioxidant Activity

Mauricio Alcolea Palafox, Nataliya P. Belskaya, Lozan T. Todorov, Irena P. Kostova

Subject: Medicine And Pharmacology, Medicine And Pharmacology Keywords: 1,2,3-triazoles; antioxidant; lanthanum; vibrational analysis; scaling

Online: 22 September 2023 (09:20:38 CEST)

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Preprint BRIEF REPORT | doi:10.20944/preprints202309.1527.v1

Quantification of the Number of Nuclear Gems as a Potential Biomarker for Spinal Muscular Atrophy

Haya Al-Hilal, Marianna Maretina, Anna Egorova, Andrey Glotov, Anton Kiselev

Subject: Neuroscience And Neurology, Medicine And Pharmacology Keywords: spinal muscular atrophy; SMN1 gene; SMN2 gene; nuclear gems; antisense oligonucleotides; splicing correction.

Online: 22 September 2023 (09:19:28 CEST)

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Preprint REVIEW | doi:10.20944/preprints202309.1526.v1

Patient-Derived Cellular Models for Polytarget Precision Medicine in Pantothenate Kinase-Associated Neurodegeneration

Mónica Ávarez-Córdoba, Marta Rey-Talaverón, Suleva Povea-Cabello, Paula Cilleros-Holgado, David Gómez-Fernández, Rocío Piñero-Pérez, Diana Reche-López, Manuel Munuera-Cabeza, Alejandra Suárez-Carrillo, Ana Romero-González, José Manuel Romero-Domínguez, Alejandra López-Cabrera, José Ángel Armengol, Jose Antonio Sánchez-Alcázar

Subject: Neuroscience And Neurology, Biology And Life Sciences Keywords: neurodegeneration with brain iron accumulation (NBIA); pantothenate kinaseassociated neurodegeneration (PKAN); pantothenate kinase 2 (PANK2); pantothenate; pantethine; vitamin E; omega 3; -lipoic acid; L-carnitine; thiamine; fibroblasts; induced neurons; precision medicine

Online: 22 September 2023 (09:18:39 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202309.1508.v1

Influence of Demagnetisation on Barkhausen Noise in the High-Strength Low-Alloyed Steel 1100 MC

Martin Pitoňák, Nikolaj Ganev, Katarína Zgútová, Jiří Čapek, Miroslav Neslušan, Karel Trojan

Subject: Mechanical Engineering, Engineering Keywords: high-strength steel; Barkhausen noise; surface heterogeneity; asymmetry

Online: 22 September 2023 (09:17:26 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202309.1525.v1

The Employee Performance Paradox: Exploring the Interplay of Work Place Well-Being, Seniority, and Workplace Bullying

Imaduddin Murdifin

Subject: Business And Management, Business, Economics And Management Keywords: workplace well-being; seniority; workplace bullying; employee performance

Online: 22 September 2023 (09:12:48 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202309.1531.v1

Malicious Office Macros Detection: Combined Features with Obfuscation and Suspicious Keywords

Xiang Chen, Wenbo Wang, Weitao Han

Subject: Security Systems, Computer Science And Mathematics Keywords: malicious document; VBA; macro; obfuscation; suspicious keywords; machine learning

Online: 22 September 2023 (09:12:01 CEST)

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Preprint CONCEPT PAPER | doi:10.20944/preprints202309.1513.v1

Preparing University Chemistry Education for a Sustainable Future in the Age of AI

Yee Seng Tan, Chien Ing Yeo, Chee-Yan Choo, Long Chiau Ming

Subject: Other, Chemistry And Materials Science Keywords: Sustainability; Sustainable Development Goals (SDGs); Chemistry education; Ethical AI; Curriculum; Data science; Generative AI

Online: 22 September 2023 (09:10:52 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202309.1523.v1

Research on Vibration Characteristics of Mountain Orchard Transporter and Optimization of Trailer

Yuping Ouyang, Jiarui Huang, Kaifang Song

Subject: Civil Engineering, Engineering Keywords: mountain orchard transporter; vibration test; trailer; transmission box; modal

Online: 22 September 2023 (09:09:00 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202309.1515.v1

Optimal Design of Laminates Orientation in a Composite Material by Genetics Algorithm and Simulated Annealing

Mauricio Torres Arellano, Aaron Burgos Vergara, Saul Piedra-Gonzalez, Erik Herrera, Edgar Adrian Franco-Urquiza

Subject: Mechanical Engineering, Engineering Keywords: composite material; laminates orientation; optimization; simulated annealing; genetic algorithm

Online: 22 September 2023 (09:07:46 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202309.1543.v1

Investigating Self-Perceived Use of Spectrum of Teaching Styles in Italian Secondary School Physical Education Teachers: A Pilot Study

Domenico Monacis, Francesca Latino, Cristina D'Arando, Dario Colella

Subject: Education, Social Sciences Keywords: quality physical education; spectrum of teaching styles; student-teacher relation

Online: 22 September 2023 (08:51:26 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202309.1539.v1

Dual-Task Interference Effects on Lower-Extremity Muscle Activities during Gait Initiation and Steady-State Gait among Healthy Young Individuals, measured using Wireless Electromyography Sensors

Ke'Vaughn Tarrel Waldon, Angeloh Stout, Kaitlin Manning, Leslie Gray, David Wilson, Gu Eon Kang

Subject: Bioengineering, Engineering Keywords: Gait Initiation; Dual Task; Muscle Activities; Wireless Electromyography

Online: 22 September 2023 (08:47:07 CEST)

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Preprint HYPOTHESIS | doi:10.20944/preprints202309.1540.v1

Concentrating Microbes from Human Urine Samples Using Paper-Based Adsorbents for Point-of-Care Molecular Assays

Isha Uttam, Sujesh Sudarsan, Rohitraj Ray, Raja Chinnappan, Ahmed Yaqinuddin, Khaled Al-Kattan, Naresh Kumar Mani

Subject: Biology And Biotechnology, Biology And Life Sciences Keywords: preconcentration; loop-mediated isothermal amplification (LAMP); Urine; microbial adhesion; hydrophobic; paper-based analytical devices (μPADs); cell surface hydrophobicity (CSH); UTI

Online: 22 September 2023 (08:46:17 CEST)

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Preprint REVIEW | doi:10.20944/preprints202309.1538.v1

Cardiovascular Diseases and Marine Oils: A Focus on Omega-3 Polyunsaturated Fatty Acids and Polar Lipids

Cliodhna Caffrey, Anna Leamy, Ellen O’Sullivan, Ioannis Zabetakis, Ronan Lordan, Constantina Nasopoulou

Subject: Food Science And Technology, Biology And Life Sciences Keywords: Cardiovascular disease; Omega-3 polyunsaturated fatty acids; Polar lipids; Cardiovascular risk; Thrombosis; Platelet-activating factor (PAF); Eicosanoids; Resolvins; Fish oil

Online: 22 September 2023 (08:44:08 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202309.1541.v1

Factors Influencing Attitudes of University Students towards ChatGPT and its Usage: A Multi-National Study Validating the TAME-ChatGPT Survey Instrument

Maram Abdaljaleel, Muna Barakat, Mariam Alsanafi, Nesreen A. Salim, Husam Abazid, Diana Malaeb, Ali Haider Mohammed, Bassam Abdul Rasool Hassan, Abdulrasool M. Wayyes, Sinan Subhi Farhan, Sami El Khatib, Mohamad Rahal, Ali Sahban, Doaa H. Abdelaziz, Noha O. Mansour, Reem AlZayer, Roaa Khalil, Feten Fekih-Romdhane, Rabih Hallit, Souheil Hallit, Malik Sallam

Subject: Education, Social Sciences Keywords: Higher education; technology acceptance; generative pre-trained transformer; curriculum design; academia

Online: 22 September 2023 (08:39:44 CEST)

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Artificial intelligence (AI)-based models hold the potential to transform higher education if adopted properly and ethically. A prime example is ChatGPT with earlier studies indicating its widespread adoption in academia and by university students. The current study aimed to identify the factors influencing the attitude towards ChatGPT and its usage among university students in Arab countries. A previous survey instrument termed Technology Acceptance Model Edited to Assess ChatGPT Adoption (TAME-ChatGPT) was administered online using a convenience-based approach among the contacts of the authors. Confirmatory factor analysis (CFA) for the survey constructs was done using root mean square error of approximation (RMSEA), standardized root mean square residual (SRMR), comparative fit index (CFI), and Tucker-Lewis index (TLI). The final study sample comprised a total of 2240 participant divided as follows: Iraq (n=736, 32.9%), Kuwait (n=582, 26.0%), Egypt (n=417, 18.6%), Lebanon (n=263, 11.7%), and Jordan (n=242, 10.8%). A total of 1048 respondents heard of ChatGPT before the study (46.8%), of which 551 used ChatGPT (52.6%). The mean scores of TAME-ChatGPT constructs showed that the ease of ChatGPT use, positive attitude towards technology and social influence, higher perceived usefulness, the influence of behavioral/cognitive factors, low perceived risks and low anxiety were the determinants of positive attitude to ChatGPT and its use. For both the attitude and usage scales of TAME-ChatGPT, CFA collectively yielded satisfactory fit indices as indicated by low RMSEA and SRMR together with high CFI and TLI. Multivariate analysis showed that attitude to ChatGPT use was significantly influenced by country of residence, age, university type, and the latest grade point average of the students. The current study confirmed the validity of TAME-ChatGPT as a survey instrument to assess the possible determinants of ChatGPT use among university students in Arab countries. The study findings highlighted that successful adoption of ChatGPT in higher education could be dependent on perceived ease of use, usefulness, positive attitudes to technology, social influence, behavioral/cognitive factors, lower anxiety, and minimal perceived risks. The utility of ChatGPT in higher education requires policies that should be tailored for various settings, considering the differences observed in attitude towards ChatGPT among participating students in this study.

Preprint ARTICLE | doi:10.20944/preprints202309.1532.v1

Adapt the Parameters of RBF Networks Using Grammatical Evolution

Ioannis G. Tsoulos, Alexandros Tzallas, Evangelos Karvounis

Subject: Artificial Intelligence And Machine Learning, Computer Science And Mathematics Keywords: Neural networks; Genetic algorithms; Genetic programming; Grammatical evolution

Online: 22 September 2023 (08:37:54 CEST)

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Preprint CASE REPORT | doi:10.20944/preprints202309.1500.v1

Diffuse Large B-cell Lymphoma Misdiagnosed as a Hematoma: Case Report

Jae Hyun Lee, Jiyoung YUN

Subject: Oncology And Oncogenics, Medicine And Pharmacology Keywords: lymphoma; large B-cell; diffuse; hematoma

Online: 22 September 2023 (08:36:21 CEST)

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Preprint CASE REPORT | doi:10.20944/preprints202309.1533.v1

Germline CSF3R Variant in Chronic Myelomonocytic Leukemia: Linking Genetic Predisposition to Uncommon Hemorrhagic Symptoms

Maria Teresa Bochicchio, Giorgia Micucci, Silvia Asioli, Martina Ghetti, Giorgia Simonetti, Alessandro Lucchesi

Subject: Biochemistry And Molecular Biology, Biology And Life Sciences Keywords: chronic myelomonocytic leukemia; CSF3R; bleeding disorders; predisposing genes; NGS

Online: 22 September 2023 (08:35:11 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202309.1498.v1

Plants Profile of Sultan Khail Valley, Hindukush Range of Pakistan: Floristic Composition, Biological Spectrum and Its Seasonal Variation

Khaista Rahman, Naveed Akhtar

Subject: Other, Biology And Life Sciences Keywords: Floristic composition; Biological Spectrum; Sultan Khail Valley; Pakistan

Online: 22 September 2023 (08:32:26 CEST)

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Preprint CONCEPT PAPER | doi:10.20944/preprints202309.1514.v1

Development of Photonic Multi-Sensing Systems Based on Molecular Gates Biorecognition and Plasmonic Sensors: The PHOTONGATE Project

Oscar Nieves Paniagua, David Ortiz de Zárate, Elena Aznar, Isabel Caballos, Eva Garrido, Ramón Martínez Mañez, Fabian Dortu, Damien Bernier, Beatriz Mengual-Chuliá, F. Xavier López-Labrador, Jens J. Sloth, Katrin Löschner, Lene Duedahl-Olesen, Natalia Prado, Martín Hervello, Armando Menéndez, Rainer Gransee, Thomas Klotzbuecher, Maria Clara Henriques Baptista Gonçalves, Fahimeh Zare, Ana Fuentes López, Isabel Fernández-Segovia, José M. Barat, Jaime Salcedo, Sara Recuero, Santiago Simón, Ana Fernández Blanco, Sergio Peransi, Maribel Gómez-Gómez, Amadeu Griol

Subject: Optics And Photonics, Physical Sciences Keywords: Photonics; Molecular gates; Localized surface plasmonic resonance (LSPR); porous silica; bio-sensing; microfluidics; respiratory viruses; chemical contaminants

Online: 22 September 2023 (08:28:33 CEST)

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Preprint COMMUNICATION | doi:10.20944/preprints202309.1496.v1

Pemafibrate Improves Alanine Aminotransferase Levels Independently of Its Lipid-lowering Effect

Azuma Watanabe, Ryoko Horigome, Yumiko Nakatsuka, Shuji Terai

Subject: Clinical Medicine, Medicine And Pharmacology Keywords: pemafibrate; Non-alcoholic fatty liver disease (NAFLD); Alanine Aminotransferase; M2-BPGi; dyslipidemia; liver fibrosis

Online: 22 September 2023 (08:26:12 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202309.1506.v1

Formation of 5-aminomethyl-2,3-dihydropyridine-4(1H)-ones from 4-amino-tetrahydropyridinylidene Salts

Werner Seebacher, Michael Hoffelner, Ferdinand Belaj, Teresa Pirker, Muaaz Aljlani, Rudolf Bauer, Eva-Maria Pferschy-Wenzig, Robert Saf, Robert Weis

Subject: Organic Chemistry, Chemistry And Materials Science Keywords: antibacterial; anticancer activity, dihydropyridin-4(1H)-ones; tetrahydropyridinylidene salts

Online: 22 September 2023 (08:24:17 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202309.1518.v1

Sustainable Bioactive Dyeing of Textiles: A Novel Strategy Using Bacterial Pigments, Natural Antibacterial Ingredients, and Deep Eutectic Solvents

Cláudia Mouro, Ana P. Gomes, Rita V. Costa, Farzaneh Moghtader, Isabel C. Gouveia

Subject: Materials Science And Technology, Chemistry And Materials Science Keywords: Bacterial pigments; Crude gel prodigiosin pigment; Natural-dyeing; Bio-mordant; L-Cysteine; Gel-based deep eutectic solvent

Online: 22 September 2023 (08:20:46 CEST)

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Textile industry is one of the major industries responsible for environmental pollution globally. This is mainly due to the use of synthetic dyes, toxic ingredients and solvents for dy-ing/treatments/protocols of textiles. Replacement of those non ecofriendly ingredients would be a very challenging target to develop novel sustainable textile dying strategies. Using biobased and bioactive pigments, antibacterial ingredients and especially natural solvents are recently pointed out as substances to included in the related formulations. In this study the dyeing ability of the crude gel prodigiosin produced by non-pathogenic bacteria Serratia plymuthica as a natural pigment was investigated on various multifiber fabrics at different condition (temperature and pH) and by using salts (NaOH and Na2S2O4) and alternative mordants (a conventional: FeSO4 and a new bio-mordant: L-Cysteine (L-Cys)) in the recipes with different compositions and especially replacing of organic solvent with a new type of gel-based Choline chloride (ChCl) : Lactic acid (LA) (1 : 2) deep eutectic solvents (DES) as a dyeing medium. For determination of the dying process performances, the color strength (K/S value) of dyed fabric and the dyeing equalization (dE) parameters were evaluated. The fastness properties of the dyed fabrics which displayed as a higher K/S value and good dE were evaluated. The nylon fabrics dyed with 3.0% owf L-Cys at pH = 8.3 improved the color fastness to washing, while the gel-based ChCl : LA (1 : 2) DES dyebath provided a better color fastness to light. Moreover, the nylon fabrics under these conditions exhibited remarkable anti-microbial activity against Staphylococcus aureus (S. aureus) and Pseudomonas aeruginosa (P. aeruginosa). As conclusion, the use of the crude gel prodigiosin pigment revealed an advantageous ability to dye the textile materials, responding to consumers' demand for more ecological and sustainable products. Furthermore, the natural reducing agent L-Cys, never tested before as a bio-mordant, and the use of gel-based DES as a dyeing medium demonstrated enhanced colorimetric and antibacterial properties on dyed nylon with crude gel prodigiosin pigment.

Preprint ARTICLE | doi:10.20944/preprints202309.1528.v1

Will the Age of Generative Artificial Intelligence Become an Age of Public Ignorance?

Dirk H.R. Spennemann

Subject: Artificial Intelligence And Machine Learning, Computer Science And Mathematics Keywords: artificial intelligence; ChatGPT; ethics; knowledge generation; language models; machine learning; strategic foresight

Online: 22 September 2023 (08:20:13 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202308.1708.v2

Attention and Self-Control Dimensions of Impulsivity Predict the Quality of Life among Male Patients Seeking Treatment for Alcohol Use Disorder: The Mediating Role of Anxiety and Severity of Alcohol Use Disorder

Prabhoo Dayal, Gauri S. Kaloiya, Rohit Verma, Nand Kumar

Subject: Public Health And Health Services, Public Health And Healthcare Keywords: quality of life; impulsivity; attention and self-control dimensions of impulsivity; alcohol use disorder; anxiety symptoms; WHOQOL-BREF

Online: 22 September 2023 (08:18:53 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202305.2161.v2

A Proof of Collatz Conjecture

HUANG Qingxue

Subject: Algebra And Number Theory, Computer Science And Mathematics Keywords: number theory; Collatz conjecture

Online: 22 September 2023 (07:42:19 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202309.1529.v1

Epidemiological Evolution and Economic Impact of the COVID-19 Pandemic in the European Union and Worldwide and Effects of Control Strategies on Them: A Descriptive Study

Joan A. Caylà, Josep M Bellmunt, Josep M Jansà, Andrés Marco, Joan-Pau Millet

Subject: Health Policy And Services, Public Health And Healthcare Keywords: COVID-19; SARS-CoV-2; mitigation strategy; Zero-COVID strategy; prevention; control; gross domestic product; evaluation

Online: 22 September 2023 (07:41:10 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202309.1517.v1

Effects of Impaired Fasting Glucose on Left Atrial Strain Evaluated by Speckle Tracking Echocardiography

Gülsüm Bingöl, Fulya Avcı Demir, Emre Özmen, Serkan Unlu, Özge Özden, Kardelen Ohtaroğlu Tokdil, Leyla Bulut Arsoy, Fatma özpamuk karadeniz, Barış Ökçün

Subject: Cardiac And Cardiovascular Systems, Medicine And Pharmacology Keywords: strain echocardiography; diabetes mellitus; fasting blood glucose

Online: 22 September 2023 (07:40:50 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202309.1516.v1

Flow Analysis and Structural Optimization of Double-chamber Parallel Flexible Valve Micropump

Fan Jiang, Jinfeng Wen, Teng Dong

Subject: Chemical Engineering, Engineering Keywords: EWOD; micropump; double-chamber; flow field; structural parameters; optimization

Online: 22 September 2023 (07:40:12 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202309.1521.v1

Operation of an Electrical-Only-Contact Photonic Integrated Chip for Quantum Random Number Generation Using Laser Gain-Switching

Seán Ó Dúill, Leidy Rodriguez, David Alvarez-Outerelo, Francisco J. Díaz-Otero, Ankit Sharma, Frank Smyth, Liam P. Barry

Subject: Electrical And Electronic Engineering, Engineering Keywords: random number generation; integrated photonics; photonics integrated circuit; laser; noise; modulation; quantum effects

Online: 22 September 2023 (07:39:28 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202309.1537.v1

Safety Evaluation of N-((3S,4S)-4-(3,4-Difluorophenyl)piperidin-3-yl)-2-fluoro-4-(1-methyl-1H-pyrazol-5-yl) benzamide (Hu7691) by a Repeated Dose 14-Day Oral Exposure Toxicity Study in Rats

Renhua Gai, Chao Chen, Wei Zhang, Ma Jian, Xiaomeng Wang, Xiaoqing Chi, Guangxing Li

Subject: Pharmacology And Toxicology, Medicine And Pharmacology Keywords: Hu7691; 14-day exposure; Oral toxicity study; SD rats; Formulation; Histopathology

Online: 22 September 2023 (07:38:10 CEST)

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Preprint REVIEW | doi:10.20944/preprints202309.1536.v1

INSIGHTS INTO THE ANTIBIOFILM MODE OF ACTION OF DISINFECTANTS AND THE ROLE OF WATER CHANNEL IN DISINFECTANT RESISTANCE

Z Mohd

Subject: Immunology And Microbiology, Biology And Life Sciences Keywords: Biofilm; disinfectant; water channel

Online: 22 September 2023 (07:25:47 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202309.1499.v1

Does a Motivational Workshop Enhance the Opening of Saving Accounts Among the Unbanked Village Defense Party (VDP) Members? Evidence From Randomized Controlled Trial

Md Monzur Morshed, And Keshav Lall Maharjan

Subject: Other, Social Sciences Keywords: Financial inclusion; Financial access; Unbanked; Motivational Workshop; Village Defense Party; Randomized Controlled Trial.

Online: 22 September 2023 (06:39:12 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202309.1505.v1

Research on the Closure and Remediation Processes of Mining Areas in Romania and Approaches to the Strategy for Heavy Metal Pollution Remediation

Violeta-Monica Radu, Anca-Marina Vîjdea, Alexandru-Anton Ivanov, Veronica-Elena Alexe, George Dincă, Valentina-Maria Cetean, Andra-Elena Filiuță

Subject: Environmental Science, Environmental And Earth Sciences Keywords: heavy metals, mining activities, pollution, remediation

Online: 22 September 2023 (06:37:03 CEST)

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Preprint REVIEW | doi:10.20944/preprints202309.1497.v1

Reasons for Removal of Miniplates Used in Fixation of Maxillofacial Bone Fractures: Systematic Review and Meta-Analysis

Nadin Abouseif, Noor Ibrahim, Mohamed Jaber, Mawada Hassan, Alaa Mohamed El-Ameen

Subject: Dentistry And Oral Surgery, Medicine And Pharmacology Keywords: Trauma; Maxillofacial; Titanium; Miniplates; Mataanalysis

Online: 22 September 2023 (06:37:01 CEST)

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Maxillofacial fractures are a prevalent occurrence, and the widespread use of miniplates to stabilize and secure these fractures during surgery is common. However, the post-surgical fate of these miniplates remains a subject of contention among surgeons. Some advocate for their removal, while others suggest leaving them in place. This study aims to perform an extensive meta-analysis of pertinent studies to ascertain the destiny of miniplates employed in maxillofacial surgery and discuss the consequences of either their extraction or retention. To execute this meta-analysis, an exhaustive search was conducted across multiple databases, encompassing PubMed, Scopus, and Google Scholar. Keywords such as "titanium miniplates," "screws," "maxillofacial surgery," "complications," and "removal" were utilized to identify pertinent studies. The search was constrained to studies published between 1989 and 2022. The analysis encompassed only studies reporting outcomes related to miniplates in maxillofacial surgery, including complication rates and removal frequencies. Eleven studies conformed to the inclusion criteria and were incorporated into the meta-analysis, encompassing a total of 2240 patients. All the studies had a retrospective design, with the largest study involving 800 patients. The overall complication rate was determined to be 13.3%. The most prevalent reasons for miniplate removal included patient preference, tooth extraction, and infections. The average time span for miniplate removal was 10.7 months, with the most prolonged reported duration being 24 years. These findings imply that immediate removal might not be imperative in the majority of instances. In conclusion, our meta-analysis underscores the necessity of removing miniplates in cases where hardware leads to a variety of complications and physical discomfort. Principal factors driving plate removal included patient requests, tooth extractions, and infections. Ordinarily, plate removal took place within the span of 6 to 12 months, with the mandible being the most frequent site for removal. These findings accentuate the significance of extended monitoring to assess the trajectory of miniplates in maxillofacial surgery and provide valuable insights for future clinical decisions. To validate these conclusions and gain deeper insights into the factors influencing plate removal in maxillofacial surgery, further research with larger participant cohorts and standardized outcome reporting is imperative.

Preprint CASE REPORT | doi:10.20944/preprints202309.1410.v1

Pericardial Adhesion and Chronic Nonspecific Neck Pain Following Thoracentesis: An Osteopathic Approach.

Bruno Bordoni, Allan Richard Escher

Subject: Complementary And Alternative Medicine, Medicine And Pharmacology Keywords: Osteopathy; osteopathic manipulation; fascia; nonspecific neck pain; diaphragm

Online: 22 September 2023 (06:35:10 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202309.1398.v1

Involvement of Epithelial to Mesenchymal Transition in Canine Mammary Tumor Progression

Madalina Luciana Gherman, Oana Zanoaga, Liviuta Budisan, Lajos Raduly, Ioana Berindan-Neagoe

Subject: Veterinary Medicine, Medicine And Pharmacology Keywords: cancer; canine; mammary tumors; epithelial to mesenchymal transitionว doxorubicin

Online: 22 September 2023 (06:33:35 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202309.1504.v1

Dual Release of Daptomycin and BMP-2 from a Composite of β-TCP Ceramic and ADA Gelatin for Bone Regeneration

Lucas Ritschl, Pia Schilling, Annette Wittmer, Annerose Serr, Hagen Schmal, Michael Seidenstuecker

Subject: Life Sciences, Biology And Life Sciences Keywords: dual release; daptomycin; BMP-2, β-TCP scaffold; ADA-gelatin gel; bone infection; bone regeneration

Online: 22 September 2023 (06:26:01 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202309.1510.v1

A Conversational Framework for Interstellar Discourse on Fundamental Physical Structures

Giampiero Esposito, Valeria Fionda

Subject: Space Science, Physical Sciences Keywords: Physics; Geometry; Interstellar communication

Online: 22 September 2023 (06:20:55 CEST)

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Preprint REVIEW | doi:10.20944/preprints202309.1519.v1

Colchicine-Induced Polyploidy in Leguminous Crops Enhances Morpho-Physiological Characteristics for Drought Stress Tolerance

Phetole Mangena, Pirtununia Mushadu

Subject: Plant Sciences, Biology And Life Sciences Keywords: colchicine; drought stress; legumes; morphological traits; physiological traits; induced polyploidy

Online: 22 September 2023 (06:15:52 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202309.1509.v1

The Surgical Guides for TADs: The Rational and Laboratory Procedures

Aonuma Michiko, Shingo Shirahama, Atsumoto Shimizu, Cristian Romanec, George Anka

Subject: Dentistry And Oral Surgery, Medicine And Pharmacology Keywords: surgical guide; orthodontics; TADs; CBCT; DICOM; SLT; CAD/CAM; 3D digital printer; dentistry; miniscrews

Online: 22 September 2023 (05:48:00 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202309.1503.v1

Hypertrophic Cardiomyopathy in Underrepresented Populations: Clinical and Genetic Landscape Based on Russian Single-Center Cohort Study

Olga S. Chumakova, Tatiana N. Baklanova, Natalia V. Milovanova, Dmitry A. Zateyshchikov

Subject: Cardiac And Cardiovascular Systems, Medicine And Pharmacology Keywords: hypertrophic cardiomyopathy; Russian; Slavic; underrepresented population; specific characteristics; genetics; MYBPC3; MYH7; TPM1; FLNC

Online: 22 September 2023 (05:31:18 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202309.1341.v3

Improving Autonomous Vehicle Reasoning with Non-Monotonic Logic: Advancing Safety and Performance in Complex Environments

Jamal Raiyn, Galia Weidl

Subject: Transportation Science And Technology, Engineering Keywords: car–following; non-monotonic logic; reasoning; naturalistic driving studies; safetycritical events; cognitive vehicles

Online: 22 September 2023 (05:30:08 CEST)

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The software design of autonomous vehicles (AVs) incorporates artificial intelligence (AI) characteristics to enhance their safety and overall driving performance. Central to vehicle’s operation is the ability to reason effectively in complex and uncertain environments. However, traditional logical systems, such as monotonic logic, often struggle to handle the inherent uncertainties and exceptions encountered in real-world scenarios. This paper proposes the utilization of non-monotonic logic in order to enhance the reasoning capabilities of autonomous vehicles. By incorporating non-monotonic reasoning, vehicles can navigate intricate traffic scenarios, make plausible inferences, and adapt their decisions when faced with conflicting information. This research aims to provide a comprehensive review of non-monotonic logic's application in autonomous vehicles, highlighting its advantages over traditional logical systems and its potential impact on safety and performance. Additionally, through this research, we seek to contribute to the advancement of autonomous driving technology by enhancing the reasoning capabilities of vehicles in various scenarios, such as car- following related to critical safety events. The personalized cognitive agent is proposed in driving behavior to consider particularly in their assumptions of homogeneous drivers. The personalized cognitive agent is incorporating heterogeneous driving behaviors, based on individual user preferences, characteristics, and needs. Driving behavior is a complex interplay of various factors, encompassing both human and external elements. Human factors, including age, experience, and gender, contribute significantly to how individuals navigate the roads. These factors influence decisions, reactions, and risk-taking tendencies on the part of drivers. Additionally, external factors such as weather conditions further compound this intricate dynamic, requiring drivers to adapt their behavior to the prevailing environment. The goal of a personalized cognitive agent is to provide tailored and customized experiences to cognitive vehicles, taking into account the unique requirements and individual preferences of occupants inside autonomous vehicles.

Preprint ARTICLE | doi:10.20944/preprints202309.1492.v1

Termites: The Marvelous Cladder and Thermoregulator in Nature: New Discoveries

Sherif Shawki Hindi, Shatha A. Alqurashi, Naimah Asid Alanazi, Khalid. A. Asiry

Subject: Forestry, Biology And Life Sciences Keywords: termite; thermoregulator; nest mortar; lignin; microcrystalline cellulose; nanocrystalline cellulose

Online: 22 September 2023 (05:25:35 CEST)

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The mortar’s composition, porosity, mechanical properties, entryways’ orientation, and condi-tioning status of the tunnels made by the Najdian Termite, Microtermes najdensis located at Hada Al-Sham village, Makkah Province, Saudi Arabia were studied. The most prevalent infected tim-ber trees by this pest were Tamarix aphylla, Pithecellobium duce, Zizyphus spina christi, Leucaena leu-cocephala, Ficus infectoria, and Phoenix dactylifera. Climate, soil, healthy wood (Wh), and termite nest skeleton (TNS) were the four components of the termite system that were investigated physi-cally, chemically, spectroscopically, and by FTIR, XRD, SEM, and TEM. It was noticed that the entryways of the termite nests are located at the southwest direction for all the infected trees studied at Hada Al-Sham village that promotes better ventilation. Concerning to the air-conditioning status within the their nest, the internal temperature (IT) was found to be milder than that for its analogous value for the outer temperature (OT) in which the IT was wormer than OT during cold durations, while it was colder than the hottest OT in hot days and vice versa. The IT’s trend had more constantancy with minor fluctuations compared to that for the OT. Moreo-ver, the IT was found to be tended to the upper OT’s limit otherwise its colder one. This finding means that these termite species prefer the hotter atmospheres comparing the colder circumstanc-es. Lignin is the prominent tracer of the organic matter used as a binder for the TNS due to its gluing ability, resistance to enzymatic degradation by the termites and their accompanied fungal community habituating the nests. The presence of both microcrystalline cellulose (MCC) and nanocrystalline cellulose (NCC) was discovered for the first time in the nest mortar reinforcing Klason lignin as the main binder. Their presence was proved by FTIR, XRD, SEM and TEM anal-yses and we satisfied that they were naturally-synthesized by the action of enzymatic hydrolysis excreted by the termites and their accompanied fungal community habituating the nests. The gross heat of combustion (GHCs) of the Wh and TNS were studied to try to find an important uti-lization of the infected woods as renewable energy resources instead of disposal them without economic benefits. These findings may be used for interpreting the durability of the termite nests to the different environmental stresses. Biomimicry of the termites’ nest from the perspective of its magic mortar with a suitable permeability, the entryways’ orientation, and the air-conditioning status can lead to modify the current construction’s designs to be more green and ecofriendly.

Preprint REVIEW | doi:10.20944/preprints202309.1089.v2

Phytovirus Vectors, Detection Techniques, and Future Directions

Gebissa Yigezu Wendimu

Subject: Insect Science, Biology And Life Sciences Keywords: insect vector; host plant; plant virus; virus detection; virus transmission

Online: 22 September 2023 (05:18:27 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202309.1483.v1

Radiation Exposure Assessment in Coronary Angiography CT Scan: Establishing Diagnostic Reference Level for Northeast Assam Population

Arnabjyoti Deva Sarma, Jibon Sharma, Manash Pratim Sarma, Mrinal Kanti Singha

Subject: Clinical Medicine, Medicine And Pharmacology Keywords: radiology; computed tomography; coronary angiography; phantom; heart

Online: 22 September 2023 (05:16:02 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202307.2063.v6

The Predicate of the Current Mathematical Knowledge Substantially Increases the Constructive and Informal Mathematics and Why It Cannot Be Adapted to Any Empirical Science

Apoloniusz Tyszka

Subject: Logic, Computer Science And Mathematics Keywords: conjecturally infinite subsets of N; constructive algorithms; current mathematical knowledge; informal notions; known algorithms; known elements of N

Online: 22 September 2023 (05:14:58 CEST)

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We assume that the current mathematical knowledge K is a finite set of statements in the public domain which is time-dependent. This set exists only theoretically. Ignoring K and its subsets, sets exist formally in ZFC theory although their properties can be time-dependent (when they depend on K) or informal. In every branch of mathematics, the set of all knowable truths is the set of all theorems. This set exists independently of K. Algorithms always terminate. We explain the distinction between algorithms whose existence is provable in ZFC and constructively defined algorithms which are currently known. By using this distinction, we obtain non-trivial statements on decidable sets X⊆N that belong to constructive and informal mathematics and refer to the current mathematical knowledge on X. This and the next sentence justify the article title. For any empirical science, we can identify the current knowledge with that science because truths from the empirical sciences are not necessary truths but working models of truth from a particular context. For a set X⊆N whose infiniteness is false or unproven, we define which elements of X are classified as known. No known set X⊆N satisfies Conditions (1)-(4) and is widely known in number theory or naturally defined, where this term has only informal meaning. (1) A known algorithm with no input returns an integer n satisfying card(X)<ω ⇒ X⊆(-∞,n]. (2) A known algorithm for every k∈N decides whether or not k∈X. (3) No known algorithm with no input returns the logical value of the statement card(X)=ω. (4) There are many elements of X and it is conjectured, though so far unproven, that X is infinite. (5) X is naturally defined. The infiniteness of X is false or unproven. X has the simplest definition among known sets Y⊆N with the same set of known elements. We prove that the set X={n∈N: the interval [-1,n] contains more than 29.5+(11!/(3n+1))∙sin(n) primes of the form k!+1} satisfies Conditions (1)-(5) except the requirement that X is naturally defined. 501893∈X. Condition (1) holds with n=501893. card(X∩[0,501893])=159827. X∩[501894,∞)={n∈N: the interval [-1,n] contains at least 30 primes of the form k!+1}. If we add to X some set W satisfying 14≤card(W)≤23, then the following statements hold: X does not satisfy Condition (1), 159827+14≤card(X), the above lower bound is currently the best known, card(X)<ω ⇒ card(X)≤159827+23, the above upper bound is currently the best known, X satisfies Conditions (2)-(5) except the requirement that X is naturally defined. We present a table that shows satisfiable conjunctions of the form #(Condition 1)∧(Condition 2)∧#(Condition 3)∧(Condition 4)∧#(Condition 5), where # denotes the negation ¬ or the absence of any symbol. No set X⊆N will satisfy Conditions (1)-(4) forever, if for every algorithm with no input, at some future day, a computer will be able to execute this algorithm in 1 second or less.

Preprint REVIEW | doi:10.20944/preprints202309.1485.v1

Biomarkers of postpartum depression: A Narrative Review

Stefan Modzelewski, Aleksandra Julia Oracz, Kamila Iłendo, Aleksandra Sokół, Napoleon Waszkiewicz

Subject: Psychiatry And Mental Health, Medicine And Pharmacology Keywords: postpartum depression, marker, biomarkers, peripartum, postpartum, cytokines, HPA, oxidative stress, genetics, nutrients, pathogenesis

Online: 22 September 2023 (05:13:21 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202308.0094.v3

Exploring the Neurobiological Roots of Emotional Behavior in Tryptophan Metabolism: Insights from Novel Kynurenine Aminotransferase Knockout Mice

Ágnes Szabó, Eleonóra Spekker, Mónika Szűcs, Keiko Takeda, Kinuyo Ozaki, Hiromi Inoue, Sayo Yamamoto, József Toldi, Etsuro Ono, László Vécsei, Masaru Tanaka

Subject: Neuroscience And Neurology, Medicine And Pharmacology Keywords: posttraumatic stress disorder (PTSD); depression; anxiety; memory; tryptophan; serotonin (5-HT); kynurenine; transaminases; conversion disorder; experimental animal models

Online: 22 September 2023 (05:03:17 CEST)

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Preprint COMMUNICATION | doi:10.20944/preprints202309.1489.v1

Cryogenic Comminution of Subsea Cables and Flowlines: A Pathway for Circular Recycling of End-of-Life Offshore Infrastructure

Ibukun Oluwoye, Arun Mathew

Subject: Environmental And Earth Sciences, Sustainable Science And Technology Keywords: material recycling; subsea cables; offshore infrastructures; flowlines; decommissioning; end-of-life

Online: 22 September 2023 (04:51:22 CEST)

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Preprint REVIEW | doi:10.20944/preprints202309.0956.v2

The Sustainable Material Culture (SMC): A Review

Romina Fucà, Serena Cubico, Piermatteo Ardolino, Francesco Rosiello, João Leitão, Giuseppe Favretto

Subject: Business, Economics And Management, Human Resources And Organizations Keywords: sustainability; segments of economics; complexity; google search; green finance (GF); debt service suspension initiatives (DSSIs); artificial intelligence (AI)

Online: 22 September 2023 (04:50:11 CEST)

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Preprint COMMUNICATION | doi:10.20944/preprints202309.1484.v1

High Prevalence of Vaginal Health Problems among the Women Living in Coastal Villages of Bangladesh

Naznine Nahar

Subject: Public Health And Healthcare, Public, Environmental And Occupational Health Keywords: vaginal problems; coastal women; water quality; Bangladesh

Online: 22 September 2023 (04:49:00 CEST)

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Preprint REVIEW | doi:10.20944/preprints202309.1522.v1

A Review and Meta-Analysis of the Effect of Atenolol on All-Cause Mortality Risk among Asians With Chronic Progressive Diseases

Abdullah Alkattan, Eman Alsalameen, Alaa Harmoush, Mhd Nour Farawati, Hind Alsharif, Nagla Mahmoud, Mhd Ali Farawati, Amjad Alfaleh, Mahmoud Kandeel, Nashwa Radwan

Subject: Medicine And Pharmacology, Medicine And Pharmacology Keywords: Atenolol; mortality; Asians; chronic progressive disease; cardiovascular disease

Online: 22 September 2023 (04:36:12 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202309.1487.v1

Simultaneous Detection of Three Subgroups of Avian Leukosis Virus Using the Nanoparticle-Assisted PCR Assay

Miaoli Wu, Shuaiqi Hu, Yujun Zhu, Feng Cong, Shengwang Liu

Subject: Biology And Life Sciences, Animal Science, Veterinary Science And Zoology Keywords: nanoPCR; avian leukosis virus; ALV-J; detection

Online: 22 September 2023 (04:33:14 CEST)

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Preprint REVIEW | doi:10.20944/preprints202309.1502.v1

A critical Review on the Neuropharmacological Effects of Kratom: An Insight from the Functional Array of Identified Natural Compounds

Rahni Hossain, Abida Sultana, Manit Nuinoon, Kunwadee Noonong, Jitbanjong Jitbanjong, Kazi Helal Hossain, Md Atiar Rahman

Subject: Medicine And Pharmacology, Neuroscience And Neurology Keywords: kratom; neurological effects; mitragynine; 7-hydroxymitragynine; antioxidant and antiinflammation

Online: 22 September 2023 (04:31:30 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202309.1507.v1

Unraveling Interdependencies: Exploring the Impact of In-vestments on Global Output Using the Leontief Matrix

Mihail Busu, Vanesa Madalina Vargas, Sorin Anagnoste

Subject: Business, Economics And Management, Business And Management Keywords: investments; global output; leontief matrix; economic impact; development levels; trade conflicts; external shocks

Online: 22 September 2023 (04:29:54 CEST)

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Preprint CASE REPORT | doi:10.20944/preprints202309.1501.v1

Prophylaxis Failure and Successful Management of Delayed-onset Malaria with Renal Complications: A Case Report with Oral Artemether-Lumefantrine Treatment

Ilir Tolaj, Gramoz Bunjaku, Murat Mehmeti, Yllka Begolli

Subject: Medicine And Pharmacology, Epidemiology And Infectious Diseases Keywords: severe malaria; Plasmodium falciparum; chemoprophylaxis failure; oral artemether-lumefantrine

Online: 22 September 2023 (02:58:59 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202309.1488.v1

Outcomes of Induction Chemotherapy in Resectable NSCLC Treated with Radical Surgery: A Pre- and POST-Operative Prognostic Factors Analysis

Chiara Catelli, Nicola Sarnicola, Tommaso Ligabue, Piero Paladini, Francesco Bloise, Carmelo Bengala, Luca Luzzi

Subject: Medicine And Pharmacology, Oncology And Oncogenics Keywords: NSCLC; neoadjuvant therapy; overall survival; locally advanced; lymph nodal downstaging; induction therapy; thoracic surgery; chemotherapy; resectable; multimodal; age

Online: 22 September 2023 (02:57:46 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202308.1157.v2

Trans-Regional Railway Corridor and Its Implication on Urbanization

Daniel Tesfaw Mengistu, Ephrem Gebremariam Beyene, Xingping Wang, Shengbo Zhao

Subject: Social Sciences, Urban Studies And Planning Keywords: industrialization; intermediate cities; urbanization; railway station; railway corridor; regional integration

Online: 21 September 2023 (14:10:55 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202309.1490.v1

Excessive Lipid Production Shapes Glioma Tumor Microenvironment

Haitham Maraqah, John Paul Aboubechara, Mones Abu-Asab, Han Sung Lee, Orwa Aboud

Subject: Medicine And Pharmacology, Oncology And Oncogenics Keywords: glioblastoma; astrocytoma; lipid accumulation; mitochondrial dysfunction; tumor microenvironment; oxidative phosphorylation; glycolysis; immune evasion; therapeutic strategies; ultrastructural analysis

Online: 21 September 2023 (13:04:57 CEST)

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Disrupted lipid metabolism is a characteristic of gliomas. This study utilizes an ultrastructural approach to characterize the prevalence and distribution of lipids within gliomas. This study made use of tissue from IDH1 wild type (IDH1-wt) glioblastoma (n=18) and IDH1 mutant (IDH1-mt) astrocytoma (n=12) tumors. We uncover a prevalent and intriguing surplus of lipids. The bulk of the lipids manifested as sizable cytoplasmic inclusions and extracellular deposits in the tumor microenvironment (TME); in some tumors the lipids were stored in the classical mem-braneless spheroidal lipid droplets (LDs). Frequently, lipids accumulated inside mitochondria, suggesting possible dysfunction of the beta-oxidation pathway. Additionally, the tumor vascula-ture are shown to have lipid deposits in their lumen and vessel walls; this lipid could have shifted in from the tumor microenvironment or have been produced by the vessel-invading tumor cells. Overproduction of lipids by the tumor is suspected to be due to a combination of two processes: i) dysfunctional oxidative phosphorylation in mitochondria that causes metabolic backup and ac-cumulation of acetyl-CoA, as well as ii) the overproduction of pyruvate due to the tumor cell reli-ance on overactive glycolysis. Tumor cells use lipids for structural components but cannot use them for energy if their oxidative phosphorylation is dysfunctional, which seems to be the case in the tumor cells we examined. This lipid-rich environment, however, offers tumor cells certain advantages: protection from the immune system, non-lipophilic drugs, and oxidative stress. Our research highlights the significant presence of lipid overproduction in both IDH1-wild type glio-blastoma and IDH1-mutant astrocytoma tumors, leading to diverse lipid accumulations in var-ious cellular compartments and structures. This lipid excess stems from disrupted beta-oxidation and dysfunctional oxidative phosphorylation pathways. The implications of this lipid-driven environment include structural support for the tumor cells and protection against immune re-sponses, non-lipophilic drugs, and free radicals.

Preprint ARTICLE | doi:10.20944/preprints202309.1491.v1

Investigation of Blood-Brain Barrier proteins as Potential Biomarkers in a Murine Model of Ischaemic Stroke

Meaad Almusined, Pragati Kakkar, Nadira Y. Yuldasheva, Hema Viswambharan, Tarun Kakkar, Sikha Saha

Subject: Biology And Life Sciences, Neuroscience And Neurology Keywords: Blood-brain barrier; Brain ischaemia; Stroke; Biomarker; Tight Junction protein

Online: 21 September 2023 (12:16:03 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202309.1419.v1

The Sociocultural Influences on Breast Cancer Screening among Rural African Women in South Africa

Nelisha Sarmah, Maureen Nokuthula Sibiya, Thandokuhle Emmanuel Khoza

Subject: Public Health And Healthcare, Public Health And Health Services Keywords: breast cancer; culture; belief; rural; South Africa

Online: 21 September 2023 (12:14:44 CEST)

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Preprint REVIEW | doi:10.20944/preprints202309.1406.v1

A Systematic Review of Microparticulate Air Pollution in Polycystic Ovary Syndrome

Narelle Stegehuis, Vicki Kotsirilos, Jim Parker

Subject: Medicine And Pharmacology, Obstetrics And Gynaecology Keywords: polycystic ovary syndrome; microparticulate air pollution; inflammation; insulin resistance; metabolic; microbiome; environment; lifestyle

Online: 21 September 2023 (12:12:52 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202309.1445.v1

Seepage Model and Pressure Response Characteristics of Non-Orthogonal Multi-Fracture Vertical Well with Superimposed Sand Body in Tight Gas Reservoir

Zhiwu Zhou, Ao Xia, Rui Guo, Lin Chen, Fengshuo Kong, Xiaoliang Zhao

Subject: Engineering, Energy And Fuel Technology Keywords: Tight gas; Superimposed sand body; Complex fracture; Seepage model; Pressure response

Online: 21 September 2023 (12:11:40 CEST)

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Preprint REVIEW | doi:10.20944/preprints202309.1467.v1

A Puzzling Mast Cell Trilogy: Anaphylaxis, MCAS and Mastocytosis

Theo Gülen

Subject: Medicine And Pharmacology, Immunology And Allergy Keywords: Anaphylaxis; MCAS; mastocytosis; KIT D816V; tryptase; mediator-release symptoms; Hereditary alpha-tryptasemia; atopy

Online: 21 September 2023 (12:10:22 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202309.1486.v1

Assessing Satellite-Based Products in Characterizing Flash Drought Under Climate Change in Northeastern South America

Humberto Alves Barbosa

Subject: Environmental And Earth Sciences, Atmospheric Science And Meteorology Keywords: Northeastern South America; flash droughts; SEVIRI; NDVI; soil moisture; SPI

Online: 21 September 2023 (12:09:04 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202309.1407.v1

Women Abused: Analysis of Assistance Provided by Urgency Mobile Service

Dalton Makoto Senda, Makcileni Paranho De Souza, Maria Dalva de Barros Carvalho, Sandra Marisa Pelloso

Subject: Public Health And Healthcare, Health Policy And Services Keywords: Violence against women; Feminicide; Pre-Hospital Emergency Care

Online: 21 September 2023 (12:07:00 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202309.1417.v1

Mice Overexpressing Wild Type RRAS2: A Novel Preclinical Model for Testing Anti-Chronic Lymphocytic Leukemia Therapies

Balbino Alarcón, Alejandro M. Hortal, Ana Villanueva, Irene Arellano, Cristina Prieto, Pilar Mendoza, Xose R Bustelo

Subject: Medicine And Pharmacology, Oncology And Oncogenics Keywords: R-RAS2; RAS; GTPases; chronic lymphocytic leukemia; B-CLL; mouse model; ibrutinib; venetoclax; new therapies; cancer treatment

Online: 21 September 2023 (12:04:56 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202309.1456.v1

Resonance Spectrum of the Surface Resistance Derivative of Organic Layered Conductors in Tilted Magnetic Fields

Danica Krstovska, Aleksandar Skeparovski

Subject: Physical Sciences, Condensed Matter Physics Keywords: organic conductors; surface resistance derivative; resonances; oscillation spectrum; tilted magnetic field

Online: 21 September 2023 (12:02:46 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202309.1468.v1

Influence of Long-Term Outdoor Storage of Rockrose (Cistus laurifolius L.) Shrub Biomass on Biofuels Quality, Pre-Treatment and Combustion Processes

Raquel Bados, Irene Mediavilla, Eduardo Tolosana, Elena Borjabad, Raquel Ramos, Miguel Fernández, Paloma Pérez, Luis Saúl Esteban

Subject: Environmental And Earth Sciences, Sustainable Science And Technology Keywords: scrub; milling; pelletisation; emissions; ash content

Online: 21 September 2023 (11:39:49 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202309.1471.v1

Electrospun Microstructured Biopolymer Fibers Containing Self-Assembled Boc-Phe-Ile Dipeptide: Dielectric and Energy Harvesting Properties

Adelino Handa, Rosa M. F. Baptista, Daniela Santos, Bruna Silva, Ana Rita O. Rodrigues, João Oliveira, Bernardo Almeida, Etelvina De Matos Gomes, Michael Belsley

Subject: Chemistry And Materials Science, Biomaterials Keywords: dipeptides; electrospinning; microfibers; dielectric properties; pyroelectricity; piezoelectricity.

Online: 21 September 2023 (11:36:43 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202309.1479.v1

Novel Encapsulating Agent for Establishing a Synbiotic Relationship with Bacillus coagulans: Microencapsulation, Bioactivity, and Gastrointestinal Simulation

Saranya Suwanangul, Pannapapol Jaichakan, Nukrob Narkprasom, Supaluck Kraithong, Kanjana Narkprasom, Papungkorn Sangsawad

Subject: Chemistry And Materials Science, Food Chemistry Keywords: antidiabetic; antioxidative activity; Bacillus coagulans spores; microencapsulation; viability

Online: 21 September 2023 (11:33:31 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202309.1474.v1

Modification of Lipid Profile, LDL Subfractions and other Cardiovascular Risk Markers in Hypercholesterolemic Women through the Sea Buckthorn Juice Consumption

Jana Kopčeková, Jana Mrázová, Katarína Fatrcová-Šramková, Peter Chlebo, Maroš Bihari, Martina Gažarová, Petra Lenártová, Marta Habánová, Alica Navrátilová

Subject: Public Health And Healthcare, Primary Health Care Keywords: berries; sea buckthorn juice; lipid profile; cholesterol; inflammation markers; intervention; anthropometric characteristics.

Online: 21 September 2023 (11:31:48 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202309.1476.v1

A Data Envelopment Analysis to Benchmark Hotel Energy Consumption in an Urban Locality

Chukwudi Okpala, Howard Njoku, Paul Ako

Subject: Engineering, Other Keywords: hotel energy consumption, data envelopment analysis, hotel benchmarking, building energy efficiency

Online: 21 September 2023 (11:30:58 CEST)

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The benchmarking of hotel energy use comprehensively identifies the controllable and uncontrollable factors affecting energy performance, including building characteristics, management strategies, operations, and maintenance systems. Other factors include climatic conditions, floor areas, operating hours, occupancy rates, and guest populations. A benchmarking study on energy consumption patterns in significant hotels (each with less than 100 rooms and an average staff strength of 40 employees), situated in the university town of Nsukka (longitude 70 23' E, latitude 60 52' N), Nigeria, was performed using the data envelopment analysis (DEA) methodology. DEA, a linear programming technique that measures the relative performances of units, was chosen as a benchmarking methodology due to its ability to handle multiple inputs and outputs. Following a correlation test, energy use intensity, diesel consumption, and the number of employees were selected as the analysis inputs, while the occupancy rate was chosen as the output variable. Data on these variables spanning 12 months were collected using questionnaires, interviews, site visits, and oral conversations with hotel managers to ensure validity. Grid-supplied electricity accounted for most of the hotels' energy needs, followed by diesel used in generators. More than 70% of the electricity use was for HVAC. From the DEA, Hotel 3 (DMU H3) had a technical efficiency score of 1, whereas adjustments were recommended for improving the efficiency scores of the other hotels, which were deemed inefficient. DMU H7 had the lowest efficiency score (0.474) and the highest identified savings for electricity and diesel. The analysis also revealed that occupancy rates were generally low in the months of June and July, coinciding with the high rainfall season with its accompanying decline in outdoor activities. Consistent with this, electricity consumption was highest in the Christmas and Easter holiday months of December, January, and April following increased travel-related activities.

Preprint ARTICLE | doi:10.20944/preprints202309.1478.v1

The Correlation between Cigarette Smoking and Rheumatoid Arthritis: An Eight-Year, Prospective, Clinical, Observational, Cohort Study

Dražen Bedeković, Damir Kirner, Ivica Bošnjak, Srđan Novak

Subject: Medicine And Pharmacology, Clinical Medicine Keywords: rheumatoid arthritis, osteoarthritis, cigarette smoking, cardiovascular risk.

Online: 21 September 2023 (11:30:14 CEST)

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Background: Cardiovascular disease (CVD) increases the risk of mortality and morbidity in patients with rheumatoid arthritis (RA). Patients with RA have a 50-60% increased risk for CVD compared with the general population. Cardiovascular risk is commonly meas-ured using the Systemic Coronary Risk Estimation 2 calculator modified for patients with RA. Traditional modifiable risk factors for CVD include arterial hypertension, dyslipidemia, insulin resistance, diabetes, cigarette smoking, and low physical activity. In this study, we analyzed the effects of smoking and the risk of CVD in patients with RA. Methods: This was a prospective, clinical, cohort study with an eight-year follow-up pe-riod. A total of 201 patients, 124 with RA (study group) and 77 with osteoarthritis (OA) (control group), were included in this study. However, only 137 patients (82 with RA and 55 with OA) completed the study. Fifty-eight patients (41 with RA and 17 with OA) died during the study period. We compared the prevalence of smoking and its association with the risk for CVD and RA. Results: The prevalence of smoking in the RA group was higher than that in the OA group (p<0.0001). Trends in the prevalence of smoking in both groups did not change signifi-cantly during the follow-up period. In the RA group, smoking was associated with the in-cidence of CVD in current smokers (p=0.028) and in patients with a history of smoking (p=0.016). These results suggest that smokers have an increased risk for RA. The trend of continued smoking in patients with RA may be attributed to attempts to reduce stress caused by RA symptoms. Conclusions: Previous studies have shown that current and former smokers with RA have more severe symptoms, more joint damage, and poorer response to therapy than those who have never smoked. However, the reason underlying the trend of continued cigarette smoking in patients with RA remains unclear. Further studies are needed to clarify the trend of continued smoking in patients with RA.

Preprint REVIEW | doi:10.20944/preprints202309.1473.v1

Towards a Better Diagnosis and Treatment of Dementia: Identifying Common and Distinct Neuropathological Mechanisms in Alzheimer’s Disease and Vascular Dementia

Anna-Sophia Wahl

Subject: Medicine And Pharmacology, Neuroscience And Neurology Keywords: Alzheimer`s, vascular dementia, neurovascular unit, neurovascular coupling, impaired blood brain barrier, neurotoxic metabolites, endothelial damage

Online: 21 September 2023 (11:28:47 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202309.1472.v1

Survival Outcomes of Patients with Head and Neck Sarcomas Submitted to Multimodal Treatment at a Single Cancer Center: A Retrospective Study

Wilber Edison Bernaola-Paredes, Eloah Pascuotte Filippetti, Carolina Abrahao, Jose Guilherme Vartanian, Marcelo Carvalho Coutinho, Karina Montenegro-Tirado, Felipe D'almeida Costa, Kleber Arturo Vallejo-Rosero, Jose Agustin Marquez-Zambrano, Antonio Cassio Assis Pellizzon

Subject: Medicine And Pharmacology, Oncology And Oncogenics Keywords: osteosarcoma; rhabdomyosarcoma, embryonal; rhabdomyosarcoma, alveolar; radiotherapy; head and neck neoplasms

Online: 21 September 2023 (11:27:47 CEST)

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Preprint REVIEW | doi:10.20944/preprints202309.1475.v1

Microbiota-Accessible Boron-Containing Compounds in Complex Regional Pain Syndrome

Cristina Elena Bita, Ion Romulus Scorei, Ananu Florentin Vreju, Anca Emanuela Muşetescu, George Dan Mogoşanu, Andrei Biţă, Venera Cristina Dinescu, Ştefan Cristian Dinescu, Cristina Criveanu, Andreea Lili Bărbulescu, Alesandra Florescu, Paulina Lucia Ciurea

Subject: Medicine And Pharmacology, Internal Medicine Keywords: complex regional pain syndrome, microbiota, boron-containing compounds, prebiotic boron, gut–brain axis, gut–musculoskeletal axis, gut–immune system axis

Online: 21 September 2023 (11:27:14 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202309.1481.v1

Identification and Characterization of ten Escherichia coli Strains encoding Novel Shiga Toxin 2 Subtypes, Stx2n as well as Stx2j, Stx2m, and Stx2o, in the United States

Rebecca L Lindsey, Arjun Prasad, Michael Feldgarden, Narjol Gonzalez-Escalona, Curtis Kapsak, William Klimke, Angela Melton-Celsa, Peyton Smith, Alexandre Souvorov, Jenny Truong, Flemming Scheutz

Subject: Biology And Life Sciences, Other Keywords: Shiga Toxin-Producing Escherichia coli; Shiga toxin subtype; Stx2n; Genome Sequence

Online: 21 September 2023 (11:26:00 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202307.1435.v2

Verifiable Privacy Preservation Scheme for Outsourcing Medical Image to Cloud Through ROI Based Crypto-Watermarking

Chuan Zhou, Yi Zhou, Xinghan An, Yan Liu, Min Wang, XiangZhi Liu

Subject: Computer Science And Mathematics, Artificial Intelligence And Machine Learning Keywords: sharing secret; data outsourcing; reversible watermarking; chaotic map

Online: 21 September 2023 (11:24:52 CEST)

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Preprint REVIEW | doi:10.20944/preprints202309.1464.v1

Nuclear Fusion in Plant Reproduction

Nanami Kobayashi, Shuh-ichi Nishikawa

Subject: Biology And Life Sciences, Plant Sciences Keywords: nuclear fusion; female gametogenesis; fertilization; membrane fusion; flowering plants; budding yeast

Online: 21 September 2023 (10:57:58 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202309.1477.v1

Clinicopathological and Prognostic Significance of Bcl2 in Breast Cancer: A Comprehensive In Silico and In Vitro Study

Shazia Sofi, Umar Mehraj, Nusrat Jan, Sheikh F. Ahmad, Manzoor Ahmad Mir

Subject: Medicine And Pharmacology, Oncology And Oncogenics Keywords: Breast Cancer; chemoresistance; metastasis; apoptosis; B cell lymphoma gene 2; oncogene; expression pattern

Online: 21 September 2023 (10:39:29 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202309.1465.v1

Regional Differences in Uptake of Vaccination against COVID-19 and Influenza in Germany—Results from the Digi-Hero Cohort

Bianca Klee, Sophie Diexer, Myka Harun Sarajan, Nadine Glaser, Mascha Binder, Thomas Frese, Matthias Girndt, Daniel Sedding, Jessica I. Hoell, Irene Moor, Michael Gekle, Rafael Mikolajczyk, Cornelia Gottschick

Subject: Public Health And Healthcare, Public Health And Health Services Keywords: COVID-19; influenza; vaccine hesitancy

Online: 21 September 2023 (10:34:49 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202309.1470.v1

Storage Stability of Meat Analogs Supplemented with Vegetable Oils

Youngjae Cho, Junhwan Bae, Jiseon Lee, Mi-Jung Choi

Subject: Biology And Life Sciences, Food Science And Technology Keywords: vegetable analog; vegetable oil; storage stability; freeze storage

Online: 21 September 2023 (10:30:40 CEST)

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Preprint HYPOTHESIS | doi:10.20944/preprints202305.0481.v2

The Food-Crushing Reflex, and Its Inhibition

Lauri Henrikki Vaahtoniemi

Subject: Biology And Life Sciences, Neuroscience And Neurology Keywords: vertebrate evolution; mesencephalic nucleus; primary afferent neuron; jaw movements; dental formulas; chewing reflexes; dental occlusion; brain stem; premaxilla; trigeminal nerve

Online: 21 September 2023 (10:29:32 CEST)

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Anterior-tooth (ANT) contacts induce short latency reflex inhibition of human jaw-closing muscles. The jaw is a rigid class 1 lever for pinpoint-targeting muscle force into a single bite-point, the pivoting food particle. See-saw reflex movements around the food particle fulcrum multiply the food-crushing force. Unpredictable jolts of reaction force caused by food-crushing are subjected to the rostral ANT and caudally to the two articulate ends of the jaw triangle. Compression/distraction strains of food-crushing must be monitored and inhibited by withdrawal reflexes. The mesencephalic ganglion (Vmes), neural myelin sheath, and muscle stretch receptors evolved subsequently to the advent of jaws to improve the velocity of proprioceptive and withdrawal reflexes. In mammalians, the spindles of the taut motor units, stretched by the food-fulcrum send excitatory monosynaptic feedback for the efferent neurons of the respective ipsilateral muscle units, via Vmes. In the Vmes, the spindle-input-mediating afferent neurons are coupled with another source of afferent feedback, which is also excitatory, from the back-tooth (BAT) mechanoreceptors. The two sources of excitatory pulses are summated and targeted for the efferent neurons to boost the stretched and taut motor units. Likewise, the afferent feedback from ANT mechanoreceptors is also coupled in the Vmes with concomitant feedback from spindles. The ANT output, however, is inhibitory to negate the excitatory feedback from the stretched jaw-muscle units. The inhibitory feed from ANT temporarily blocks the excitatory potential of masticatory motor efferent neurons to protect the ANT and jaw-joints from inadvertent strains. The inhibitory inputs from ANT alternate with the excitatory inputs from BAT to determine which jaw-closing muscle units are activated or inhibited at any given instant of food-crushing. The Vmes exists in all jawed vertebrates, and its’ evolution was probably motivated by demands for the control of bite force. The monosynaptic unilateral food-crushing excitatory and inhibitory reflexes (UFCR) override the coexisting bilaterally executed feed for jaw muscles from the central nervous system. Hypothesis: The Vmes-mediated UFCR combine neural inputs from tooth contacts with concomitant feedback from muscle stretch receptors for the control of mammalian food-crushing bite force.

Preprint ARTICLE | doi:10.20944/preprints202309.1450.v1

Automatic P-Phase Onset Time Picking Method of Microseismic Monitoring Signal Underground Mine Based on Noise Reduction and Multiple Detection Indexes

Rui Dai, Yibo Wang, Da Zhang, Hu Ji

Subject: Environmental And Earth Sciences, Geophysics And Geology Keywords: Microseisms; P-phase onset time picking; STA/LTA method; AIC method; Skew and Kurtosis method; Wavelet coefficient threshold denoising in time-frequency domain.

Online: 21 September 2023 (10:05:54 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202309.1466.v1

Analytical Quality by Design (AQbD) of the TLCScanner Method for the Determination of Radiochemical Purity of the Radiopharmaceutical Sodium Iodide 131I Oral Solution

Miguel Vasquez, Américo Castro-Luna, Norma Julia Ramos-Cevallos, Donald Ramos-Perfecto, Mario Alcarraz-Curi, Jacqueline Segura-Vasquez, Danny Cáceres-Antaurco

Subject: Medicine And Pharmacology, Pharmacy Keywords: AQbD; CAA; MODR; Radiochemical purity; TLC-Scanner; Radiopharmaceutical; Sodium iodide.

Online: 21 September 2023 (09:57:22 CEST)

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The objective of the study was to apply the principles of analytical quality by design (AQbD) to the analytical method for the determination of the radiochemical purity (PQR) of the radiopharmaceutical sodium iodide 131I oral solution, by means of thin layer chromatography (TLC) with a Radio-TLC scanner, the same one that allows to evaluate the quality of the product. For the AQbD, the analytical objective profile (ATP), critical quality attributes (CQA), risk management, the method operable design region (MODR) were defined through the response surface methodology for method optimization using the MINITAB ® software, Control Strategy and the validation of the method where the parameters of selectivity, linearity, precision, robustness, detection limit, quantification limit, range and stability of the sample solution were evaluated. Under the experimental conditions, the conditions of the method were demonstrated by TLC-Scanner and optimization was carried out for an injection volume of 3 µL, radioactive concentration of 10 mCi/mL and carrier volume of 40 µL. It was statistically demonstrated that the method is selective for the 131I iodide band Rf of 0,8 and for the radiochemical impurity IO₃⁻ Rf of 0.6, linearity from 6,0 to 22.0 mCi/mL, intermediate precision with Global RSD of 0,624%, robustness with global RSD 0,101%, detection limit of 0,09 mCi/mL, quantification limit of 0.53 Ci/mL, conforming range, and stability of the sample solution evaluated over time 0, 2 and 20 hours with a global RSD of 0,362%, obtaining consistent results. The development of the method based on AQbD allowed the generation of a design space and an operational space with knowledge of all the characteristics and limitations of the method, likewise in all the operations the conformity of the tests to the acceptance criteria was verified. The validity of our method is concluded under the established conditions, suitable for use in the manufacturing process of sodium iodide 131I and application in nuclear medicine services.

Preprint ARTICLE | doi:10.20944/preprints202309.0350.v3

Study on Structural Stability of ZrO2 and YSZ: Doping-Induced Phase Transitions and Fermi Level Shift

Dilshod Nematov, Amondulloi Burkhonzoda, Kholmirzo Kholmurodov, Andriy Lyubchyk, Sergiy Lyubchyk, Svitlana Lyubchyk

Subject: Chemistry And Materials Science, Nanotechnology Keywords: zirconium dioxide; stability; yttrium-stablized ZrO2 (YSZ); oxygen vacancy; enthalpy and entropy; doped-induced phase transition; fermi level shift

Online: 21 September 2023 (09:56:20 CEST)

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In this study, we considered the structural stability, electronic properties, and phonon dispersion of the cubic (c-ZrO₂), tetragonal (t-ZrO₂), and monoclinic (m-ZrO₂) phases of ZrO₂. We found that the monoclinic phase of zirconium dioxide is the most stable among the three phases in terms of total energy, lowest enthalpy, highest entropy, and other thermodynamic properties. The smallest negative modes were found for m-ZrO₂. Our analysis of the electronic properties showed that during the m–t phase transformation of ZrO₂, the Fermi level first shifts by 0.125 eV toward higher energies and then decreases by 0.08 eV in the t–c cross-section. The band gaps for c-ZrO₂, t-ZrO₂, and m-ZrO₂ are 5.140 eV, 5.898 eV, and 5.288 eV, respectively. Calculations based on the analysis of the influence of doping 3.23, 6.67, 10.35, and 16.15 mol. %Y₂O₃ onto the m-ZrO₂ structure showed that the enthalpy of m-YSZ decreases linearly, which accompanies further stabilization of monoclinic ZrO₂ and an increase in its defectiveness. A doping-induced and concentration-dependent phase transition in ZrO₂ under the influence of Y₂O₃ was discovered, due to which the position of the Fermi level changes and the energy gap decreases. It has been established that, not only for pure systems but including those doped with Y₂O₃, the main contribution to the formation of the conduction band is made by the p-states of electrons. The t-ZrO₂ (101) and t-YSZ (101) surface models were selected as optimal surfaces for water adsorption based on a comparison of their surface energies. An analysis of the mechanism of water adsorption on the surface of t-ZrO₂ (101) and t-YSZ (101) showed that H₂O on unstabilized t-ZrO₂ (101) is adsorbed dissociatively with an energy of -1.22 eV, as well as by the method of molecular chemisorption with an energy of - 0.69 eV and the formation of a hydrogen bond with a bond length of 1.01 Å. In the case of t-YSZ (101), water is molecularly adsorbed onto the surface with an energy of -1.84 eV. Dissociative adsorption of water occurs at an energy of -1.23 eV, near the yttrium atom. The results show that ab initio approaches are able to describe the mechanism of doping-induced phase transitions in (ZrO₂+Y₂O₃)-like systems, based on which it can be assumed that DFT calculations can also flawlessly evaluate other physical and chemical properties of YSZ, which have not yet been studied quantum chemical research. The obtained results complement the database of research works carried out in the field of the application of biocompatible zirconium dioxide crystals and ceramics in green energy generation and can be used in designing humidity-to-electricity converters and creating solid oxide fuel cells based on ZrO₂.

Preprint REVIEW | doi:10.20944/preprints202309.1436.v1

Cobalt in Soil-Plant-Human System: A Data-Analysis Review

Sana Khalid, Muhammad Shahid, Rabia Naz, Nabeel Khan Niazi, Abdullah A. Al-Kahtani, Zeid A. ALOthman, Raqash Fatima, Behzad Murtaza

Subject: Environmental And Earth Sciences, Environmental Science Keywords: Cobalt; toxicity; plants; detoxification; micronutrient; macronutrients; anti-oxidative enzymes

Online: 21 September 2023 (09:53:29 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202309.1426.v1

AHP-SWOT Analysis of the Development Strategy of China’s Northeast Economy Under the New Economic Situation

Jin Liu

Subject: Business, Economics And Management, Economics Keywords: China Northeast; SWOT Analysis; Analytic Hierarchy Process (AHP); Economics

Online: 21 September 2023 (09:47:43 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202307.1580.v3

Annual Solar Geoengineering: Mitigating Yearly Global Warming Increases

Alec Feinberg

Subject: Environmental And Earth Sciences, Environmental Science Keywords: solar geoengineering; space mirrors; earth mirrors; desert modification; space clusters; stratosphere injection

Online: 21 September 2023 (09:45:43 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202309.1469.v1

UAV takeoff in Windy Conditions using DQN

Xabier Olaz, Daniel Aláez, Pablo De Porcellinis, Manuel Prieto, José Javier Astrain

Subject: Computer Science And Mathematics, Artificial Intelligence And Machine Learning Keywords: machine learning; DQN; gazebo; navigation

Online: 21 September 2023 (09:43:56 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202309.1420.v1

The End of Life of PV Systems: Is Europe Ready for It?

Mladen Bošnjaković, Mato Galović, Jasmin Kuprešak, Tomislav Bošnjaković

Subject: Environmental And Earth Sciences, Waste Management And Disposal Keywords: PV system; End of life; Recycling; Re-use

Online: 21 September 2023 (08:55:33 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202309.1441.v1

Fine-grained image classification network based on complementary learning

Hu Jing, Wang Meng Yao, Zhang Ru MIn, Lian Bing Quan

Subject: Computer Science And Mathematics, Artificial Intelligence And Machine Learning Keywords: fine grain image recognition; Inception-V3; reinforcement complementary learning; complementary learning; inter-class gap

Online: 21 September 2023 (08:54:27 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202309.1440.v1

Numerical Investigation of Geometry Effect Channel on Fuel Source Flow Distribution in Micro Gas Turbine Annular Combustor

Sebastian Andrew, Sanaz Dehghaniyan

Subject: Engineering, Aerospace Engineering Keywords: Micro gas turbine, fuel supply nozzle, combustion chamber, fuel distribution.

Online: 21 September 2023 (08:53:30 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202309.1430.v1

The Technogenic Deposits’ Development as a Factor of Overcoming Resource Limitations and Ensuring Sustainability

Ivan Potravny, Andrey Novoselov, Irina Novoselova, Violetta Gassiy, Davaakhuu Nyamdorj

Subject: Business, Economics And Management, Economics Keywords: depletion of natural capital; mining; technogenic deposits; mining dumps; circular economy; environmental protection; Erdenet Mining Corporation SOE; Mongolia

Online: 21 September 2023 (08:52:35 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202309.1444.v1

Superb Li-ion storage of Sn-based anode assisted by conductive hybrid buffering matrix

Jinsil Shin, Sung-Hoon Park, Jaehyun Hur

Subject: Engineering, Chemical Engineering Keywords: Sn; hybrid TiO2-C matrix; ternary composite; anode; Li-ion batteries

Online: 21 September 2023 (08:51:41 CEST)

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Preprint BRIEF REPORT | doi:10.20944/preprints202309.1421.v1

Proteinuria and significant dehydration in a short-steep triathlon: Preliminary report

Daniel Rojas-Valverde, Cindy Castro, Diego A. Bonilla, Luis A. Cardozo, Carlos D. Gómez-Carmona

Subject: Medicine And Pharmacology, Anatomy And Physiology Keywords: Physical endurance; renal function; exercise-induce dehydration, athlete health, urinary biomarkers, physiological stress.

Online: 21 September 2023 (08:49:56 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202309.1438.v1

The Multivariate Regression Models Suggested as Tools for Categorizing Solitarious and Gregarious Groups of the Main Pest Locust, Schistocerca gregaria, Produce Reproducible Results

Soumia Saadi, NOUREDDINE BAKKALI, Rubén Martín Blázquez, Abdelmounim Badih, Mohammed Bakkali

Subject: Biology And Life Sciences, Insect Science Keywords: Locust; Phase change; Outbreak; Solitarious; Gregarious; Model

Online: 21 September 2023 (08:49:02 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202309.1447.v1

Cracking Resistance of Steam-Cured Precast Concrete with Modified Fly Ash Cement

Aghiad Alhafez, Shingo Miyazawa, Nobukazu Nito, Ryuichiroh Kuga, Etsuo Sakai

Subject: Engineering, Civil Engineering Keywords: fly ash; precast concrete; compressive strength; steam curing; high alite cement; 3D FEM analysis; drying shrinkage; cracking resistance

Online: 21 September 2023 (08:47:55 CEST)

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