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Preprint ARTICLE | doi:10.20944/preprints202306.0064.v2

Reconstructing the Global Stress of Marine Structures Based on Artificial Intelligence

Tao Zhang, Jiajun Hu, Erkan Oterkus, Selda Oterkus, Xueliang Wang, Zhentao Jiang, Qua Zhu, Guocai Chen

Subject: Marine Engineering, Engineering Keywords: n/a; ship and Ocean Engineering; Marine Structures; Global Stress; Artificial Intelligence; structure health monitoring (SHM)

Online: 8 June 2023 (10:52:36 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202306.0635.v1

Exploring the Connection Between Clean and Dirty Energy: Implications for the Transition to a Carbon Resilient Economy

Rui Dias, Nuno Teixeira, Paulo M. Alexandre, Mariana Chambino

Subject: Econometrics And Statistics, Business, Economics And Management Keywords: clean energy; dirty energy; dependency; hedge; safe haven

Online: 8 June 2023 (10:50:42 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202306.0634.v1

Project Leadership Functions and the Associated Behaviour for Projects and Project Organizations

Oluseye Olugboyega, Obuks Ejohwomu, Emmanuel Dele Omopariola, Alohan Omoregie

Subject: Architecture, Building And Construction, Engineering Keywords: project leadership; project leadership theory; project leadership model; organizational leadership

Online: 8 June 2023 (10:47:59 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202306.0633.v1

Roux-En-Y Gastric Bypass Improves Adiponectin to Leptin Ratio and Inflammatory Profile in Severely Obese Women With and Without Metabolic Syndrome: A Randomized Controlled Trial

Sandra M.B.P. Moreira, Andre L. L. Bachi, Elias I. Jirjos, Carlos A. Malheiros, Sergio Vencio, Vera Lúcia dos Santos Alves, Alan R. T. Sousa, Lucenda A. Felipe, Eduardo A. Perez, Maria E. M. Lino, Shayra K. A. Souza, Juliana M. B. Santos, Miriã C. Oliveira, Adriano Luís Fonseca, Carlos H. M. Silva, Rodolfo P Vieira, Giuseppe Insalaco, Wilson R. Freitas Júnior, Luis V. F. Oliveira

Subject: Primary Health Care, Public Health And Healthcare Keywords: Roux-en-Y Gastric Bypass; Adiponectin to leptin ratio; Inflammatory profile; Severely obese; Metabolic syndrome

Online: 8 June 2023 (10:47:49 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202306.0632.v1

Intermittent and Mild Cold Stimulation Maintains the Immune Function Stability by Increasing the Levels of Intestinal Barrier Genes of Broilers

Lu Xing, Tingting Li, Yong Zhang, Jun Bao, Haidong Wei, Jianhong Li

Subject: Animal Science, Veterinary Science And Zoology, Biology And Life Sciences Keywords: broiler; duodenum; jejunum; production performance; intestinal barrier; immunoglobulin

Online: 8 June 2023 (10:46:21 CEST)

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Preprint REVIEW | doi:10.20944/preprints202306.0631.v1

Effectiveness of Silymarin, Sulforaphane, Lycopene, Green Tea, Tryptophan, Glutathione and Escin on Human Health: Results of a Narrative Review

Francesco Sebastiani, Carlo D'Alterio, Cristina Vocca, Luca Gallelli, Fabrizo Palumbo, Tommaso Cai, Alessandro Palmieri

Subject: Public Health And Health Services, Public Health And Healthcare Keywords: sulphoraphane; silymarin; lycopene; glutathione; escin; tryptophan; green tea; men health; prevention

Online: 8 June 2023 (10:45:43 CEST)

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Preprint CONCEPT PAPER | doi:10.20944/preprints202306.0630.v1

Design of Metamaterial Antenna for Wideband Applications

Gokul R, Deepak Akash Raj T, Charan M, Gnaneshwaran S, Gomatheeswari Preethika C

Subject: Other, Engineering Keywords: Metamaterial; wideband; Microstrip patch; unit cell; Wi-Fi 6E

Online: 8 June 2023 (10:39:35 CEST)

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Preprint REVIEW | doi:10.20944/preprints202306.0629.v1

Metabolic Reprogramming Toward Aerobic Glycolysis Involved in the Brain Amyloid Pathology

Toshiyuki Murai, Satoru Matsuda

Subject: Neuroscience And Neurology, Biology And Life Sciences Keywords: glucose metabolism; aerobic glycolysis; Warburg effect; Alzheimer’s disease; amyloid-β; ketogenic diet

Online: 8 June 2023 (10:39:29 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202306.0628.v1

Studying Anti-virulence Activity of Meta-Bromo-Thiolactone against Staphylococcus aureus and MRSA Phenotypes

Rihaf Alfaraj, Esra K Eltayb, Bashayer M AlFayez, Amjad S Abohamad, Eram Eltaher, Naifa A Alenazi, Sandra Hababah, Hamad M Alkahtani, Thamer A. Almangour, Fulwah Y Alqahtani, Fadilah Sfouq Aleanizy

Subject: Immunology And Microbiology, Biology And Life Sciences Keywords: Staphylococcus aureus; MRSA; mBTL; mBTL-ChNPs; antibiotic resistance; quorum sensing; virulence; biofilm

Online: 8 June 2023 (10:36:45 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202306.0627.v1

An Evolutionary Analysis of Higher-Order Interaction Collaborative Innovation Networks in China's New Energy Vehicle Industry

Yuan Yuan, Jinli Guo, Zhaohua Guo

Subject: Econometrics And Statistics, Business, Economics And Management Keywords: New energy vehicle; Higher-order interaction network; Generalized degree; Simplicial complex

Online: 8 June 2023 (10:35:23 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202306.0626.v1

Could Systemic Inflammatory Index Predict Diabetic Kidney Injury in Type 2 Diabetes Mellitus?

Tuba Taslamacioglu Duman, Buse Balci, Feyza Nihal Ozkul

Subject: Internal Medicine, Medicine And Pharmacology Keywords: diabetic kidney injury; inflammation; systemic inflammatory index

Online: 8 June 2023 (10:26:17 CEST)

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Preprint REVIEW | doi:10.20944/preprints202306.0625.v1

A State of the Art: Numerical Methods to Simulate Desiccation Cracks in Clayey Soils

Hector Ulises Levatti

Subject: Civil Engineering, Engineering Keywords: desiccation cracks in clayey soils; finite element method; lattice Boltzmann method; discrete element method; cellular automaton method; phase field method

Online: 8 June 2023 (10:20:07 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202306.0624.v1

Oxidation Effects on Short-Term Creep Response in Air of Commercially Pure Titanium (CP-2 Ti)

Stefano Spigarelli, Michael Regev, Alberto Santoni

Subject: Metals, Alloys And Metallurgy, Chemistry And Materials Science Keywords: creep; oxidation; titanium; constitutive equations

Online: 8 June 2023 (10:18:37 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202306.0623.v1

Automatic Epileptic Seizure Prediction Based on Convolutional Neural Network and EEG Signal

Golamali Alizadeh, Tohidy Yousefi Rezaii, Saeed Meshgini

Subject: Bioengineering, Engineering Keywords: Epilepsy; Electroencephalogram; Convolutional neural networks; Brain signal integral; Brain signal derivative

Online: 8 June 2023 (10:13:28 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202306.0622.v1

Short-term Effects of Manual Therapy Plus Capacitive and Resistive Electric Transfer Therapy in Individuals with Chronic Non-specific Low Back Pain: A Randomized Clinical Trial Study

Konstantinos Kasimis, Paris Iakovidis, Dimitrios Lytras, Georgios Koutras, Ioanna P. Chatziprodromidou, Antonis Fetlis, Stefania Rafailia Ntinou, Natalia-Maria Keklikoglou, Antigoni Samiotaki, Georgios Chasapis, Georgia Tarfali, Thomas Apostolou

Subject: Physical Therapy, Sports Therapy And Rehabilitation, Public Health And Healthcare Keywords: Keywords: Chronic Low back pain; Manual therapy; Capacitive and Resistive Electric Transfer Therapy

Online: 8 June 2023 (10:13:14 CEST)

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Background: Chronic non-specific low back pain (CNSLBP) is defined as back pain that lasts longer than 12 weeks. Objectives: To investigate the efficacy of manual therapy (MT) program combined with Capacitive and Resistive Electric Transfer (TECAR) therapy in individuals with CNSLBP. Method: Sixty adults with CNSLBP were randomly equally divided into three groups. The first group followed an MT protocol in the lumbar region (MT group), the second group followed the same MT protocol combined with TECAR therapy (MT + TECAR group) using a conventional capacitive electrode as well as a special resistive electrode bracelet and the third group (Control group) received no treatment. Both intervention programs included six treatments over two weeks. Pain in the last 24 hours with the Numeric Pain Rating Scale (NPRS), functional ability with the Roland-Morris Disability Questionnaire (RMDQ), Pressure Pain Threshold (PPT) in the lumbar region with pressure algometry, and mobility of the lumbo-pelvic region through fingertip-to-floor distance (FFD) test were evaluated before and after the intervention period with a one-month follow-up. Analysis of variance with repeated measures was applied. Results: In the NPRS score, both intervention groups showed statistically significant differences compared to the control group both in the second week as well as in the one-month follow-up (p < .001). Between-groups differences were also noticed between the two intervention groups in the second week (p < .05). Differences in the RMDQ score in the second week and on the one-month follow-up were detected between the intervention groups and the control group (p < .001), while differences between the two intervention groups were only detected in the one-month follow-up (p < .001). Regarding the PPT values, differences were found mainly between the MT + TECAR and the control group and between the MT + TECAR and the MT group (p < .05), with the MT + TECAR group in most cases showing the greatest improvement compared to the other two groups, which remained statistically significant in the one-month follow-up (p < .05). Finally, both intervention groups improved the mobility of the lumbo-pelvic region in both time points compared to the control group without, however, statistically significant differences between them (p> .05). Conclusion: The application of an MT protocol with TECAR therapy appeared more effective than conventional MT as well as compared to the control group in reducing pain and disability and improving PPT in individuals with CNSLBP. No further improvement was noted in mobility of the lumbo-pelvic region by adding TECAR to the MT intervention.

Preprint ARTICLE | doi:10.20944/preprints202306.0621.v1

Simultaneous Tracking and Recognizing Drone Targets with Millimeter-Wave Radar and Convolutional Neural Network

Suhare Solaiman, Emad Alsuwat, Rajwa Alharthi

Subject: Computer Networks And Communications, Computer Science And Mathematics Keywords: mmWave radar; cloud points; target tracking; target recognition

Online: 8 June 2023 (10:10:31 CEST)

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Preprint TECHNICAL NOTE | doi:10.20944/preprints202306.0620.v1

Microbial PolyHydroxyAlkanoate (PHA) Biopolymers – Intrinsically Natural

Anindya Mukherjee, Martin Koller

Subject: Bioengineering, Engineering Keywords: biopolymers; green chemistry principles; natural polymers; polyhydroxyalkanoates

Online: 8 June 2023 (10:09:13 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202305.1053.v2

Food Front-of-pack Labelling and the Nutri-Score Nutrition Label—Poland-wide Cross-sectional Expert Opinion Study

Mariusz Panczyk, Hubert Dobrowolski, Beata I. Sińska, Alicja Kucharska, Mariusz Jaworski, Iwona Traczyk

Subject: Food Science And Technology, Biology And Life Sciences Keywords: consumer awareness; dietary choices; front-of-pack label; Nutri-Score; nutrition labelling

Online: 8 June 2023 (10:06:48 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202306.0619.v1

A Nonequilibrium Thermodynamic Approach for Analysis of Power Conversion Efficiency in the Wind Energy System

Ihor Shchur, Marek Lis, Yurii Biletskyi

Subject: Energy And Fuel Technology, Engineering Keywords: nonequilibrium; thermodynamics; energy processes; wind energy conversion system (WECS); vertical axis wind turbine (VAWT); permanent magnet synchronous generator (PMSG); cascade connection.

Online: 8 June 2023 (10:05:18 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202306.0618.v1

A Comparative Study of the Effect of Water Susceptibility on Polyethylene Terephthalate–Modified Asphalt Mixes Under Different Regulatory Procedures

D. Movilla-Quesada, Aitor C. Raposeiras, E. Guiñez, MA Frechilla-Alonso

Subject: Civil Engineering, Engineering Keywords: Asphalt mixes; moisture damage; indirect tensile strength; polyethylene terephthalate; international standards

Online: 8 June 2023 (09:56:04 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202306.0617.v1

Neuroprotective and Disease Modifying Effects of the Triazinetrione ACD856, a Positive Allosteric Modulator of Trk-Receptors for the Treatment of Cognitive Dysfunction in Alzheimer’s Disease

Cristina Parrado-Fernandez, Sanja Juric, Maria Backlund, Märta Dahlström, Nather Madjid, Veronica Lidell, Azita Rasti, Johan Sandin, Gunnar Nordvall, Pontus Forsell

Subject: Neuroscience And Neurology, Medicine And Pharmacology Keywords: Brain-derived neurotrophic factor; nerve growth factor; Alzheimer’s disease; allosteric modulator; cognitive function; anti-depressant

Online: 8 June 2023 (09:55:01 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202306.0616.v1

Negative Contrast: A Simple And Efficient Image Augmentation Method In Crop Disease Classification

Jiqing Li, Zhendong Yin, Dasen Li, Yanlong Zhao

Subject: Artificial Intelligence And Machine Learning, Computer Science And Mathematics Keywords: Crop Disease Classification; Crop Disease Dataset; Image Augmentation

Online: 8 June 2023 (09:47:54 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202306.0615.v1

Assessment of Charge Initiation Techniques Effect on Blast Fragmentation and Environmental Safety: An Application of WipFrag Software

Blessing Olamide Taiwo, Yewuhalashet Fissha, Thomas Palangio, Andrew Palangio, Hajime Ikeda, N.Rao Cheepurupalli, Naseer Muhammad Khan, Adams Abiodun Akinlabi, Oluwaseun Victor Famobuwa, Joshua Oluwaseun Faluyi, Youhei Kawamura

Subject: Mining And Mineral Processing, Engineering Keywords: marble; small-scale mining; blast impact; fragments size characterization; WipFrag,

Online: 8 June 2023 (09:44:49 CEST)

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Preprint REVIEW | doi:10.20944/preprints202306.0614.v1

Efficacy and Safety of Biological Therapies and Jak Inhibitors in Older Patients with Inflammatory Bowel Disease

Walter Fries, Giorgio Basile, Federica Bellone, Giuseppe Costantino, Anna Viola

Subject: Gastroenterology And Hepatology, Medicine And Pharmacology Keywords: frailty, comorbidities, Crohn's disease, ulcerative colitis, infections, malignancies

Online: 8 June 2023 (09:30:13 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202306.0613.v1

Assessment of Genetic Diversity in Winged Bean [Psophocarpus Tetragonolobus (L.) DC.] Accessions Using Morphological Traits and Microsatellite Markers

Temitope Esther Olatunde, Adeolu Moses Adebayo, Ayomide Ajoke Bhadmus, Idris Ishola Adejumobi, Olaniyi Oyatomi, Benjamin Faloye, Michael Abberton

Subject: Agricultural Science And Agronomy, Biology And Life Sciences Keywords: Accessions; genetic diversity; morphological traits; SSRs; winged bean

Online: 8 June 2023 (09:25:39 CEST)

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Preprint COMMUNICATION | doi:10.20944/preprints202306.0612.v1

Evaluation of the Mannan Antigen Assay in Neonates with or without Candida albicans Colonization

Vasiliki Bourika, Tania Siahanidou, Kalliopi Theodoridou, Athanasios Tsakris, Georgia Vrioni, Athanasios Michos

Subject: Epidemiology And Infectious Diseases, Medicine And Pharmacology Keywords: mannan; candida; carriage; infant; neonate

Online: 8 June 2023 (09:17:54 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202306.0611.v1

Is there a risk for Semaglutide Misuse? Focus on the Food and Drug Administration-FDA Adverse Events Reporting System (FAERS) pharmacovigilance dataset

STEFANIA CHIAPPINI, Rachel Vickers-Smith, Duccio Gabriele Papanti, John Martin Corkery, Amira Guirguis, Giovanni Martinotti, Stefano L. Sensi, Fabrizio Schifano

Subject: Medicine And Pharmacology, Medicine And Pharmacology Keywords: semaglutide; drug misuse; drug abuse; pharmacovigilance; image- and performance-enhancing (IPED) drugs; glucagon-like peptide-1 (GLP-1) agonists

Online: 8 June 2023 (09:01:58 CEST)

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Preprint REVIEW | doi:10.20944/preprints202306.0609.v1

An Intriguing Purview on the Design of Macrocyclic Inhibitors for Unexplored Protein Kinases through Their Binding Site Comparison

Swapnil P. Bhujbal, Jung-Mi Hah

Subject: Medicine And Pharmacology, Medicine And Pharmacology Keywords: Kinases; human diseases; macrocyclic inhibitors; drug discovery

Online: 8 June 2023 (08:54:08 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202305.1684.v3

Reference Values for the Grocery Shelving Test among United Arab Emirates Population: A Cross Sectional Study

Gopala Krishna Alaparthi, Aishwarya Prabhakar Gatty, Huda Isa, Latifa Hassan, Noura Khalid, Abdullah Osman, Sara Mahmoud, May Tamim, Kalyana Chakravarthy Bairapareddy, Arthur De Sa Ferreira

Subject: Pulmonary And Respiratory Medicine, Medicine And Pharmacology Keywords: Arm elevation; Grocery Shelving Test; Functional assessment; Reference values; Upper limb activities

Online: 8 June 2023 (08:52:16 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202306.0610.v1

Early Detection of Pre-Cancerous and Cancerous Cells Using Raman Spectroscopy-Based Machine Learning

Uraib Sharaha, Daniel Hania, Itshak Lapidot, Ahmad Salman, Mahmoud Huleihel

Subject: Other, Public Health And Healthcare Keywords: Cancer; Raman spectroscopy; machine learning; normal fibroblast cells (NFC); NIH/3T3; MBM (cancerous cells)

Online: 8 June 2023 (08:52:05 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202306.0575.v1

Large Eddy Simulation Inflow Generation Using Reduced Length Scales for Low-Rise Buildings

Ava Shahrokhi, Julien Berthaut-Gerentes, Lin Ma, Derek Ingham, Mohamed Pourkashanian

Subject: Mechanical Engineering, Engineering Keywords: large eddy simulation; integral length scale; wind assessment; wind measurement

Online: 8 June 2023 (08:47:38 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202306.0606.v1

Heat Wave Magnitude Projection in the Middle Awash Basin Under Coupled Model Intercomparison Project the 6th Phase (CMIP6)

Tadele Badebo Badacho

Subject: Atmospheric Science And Meteorology, Environmental And Earth Sciences Keywords: Awash Basin; Climate change; climate extreme; CMIP6 models; Heat wave

Online: 8 June 2023 (08:45:18 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202306.0608.v1

Educational Model of Electric Potential, Electrochemical Reactions, and Species Transport in PEM Fuel Cell

Ambrož Kregar, Klemen Zelič, Andraž Kravos, Tomaž Katrašnik

Subject: Chemical Physics, Physical Sciences Keywords: Fuel Cell; PEMFC; Modelling

Online: 8 June 2023 (08:25:02 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202306.0607.v1

Material Evaluation and Dynamic Powder Deposition Modeling of PEEK/CF Composite for Powder-bed Fusion Process

Jiang Li, Fulun Peng, Hongguang Li, Zhibing Ru, Junjie Fu, Wen Zhu

Subject: Other, Engineering Keywords: Powder-bed fusion; Composite polymers; Discrete element method; Material characterization; Additive manufacturing

Online: 8 June 2023 (08:19:32 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202306.0601.v1

Development of AI and Robotics Assisted Automated Pavement Crack Evaluation System

Md. Al-Masrur Khan, Regidestyoko Wasistha Harseno, Seong-Hoon Kee, Abdullah-Al Nahid

Subject: Civil Engineering, Engineering Keywords: crack detection; deep learning; mobile robotic system; NDE analysis; pavement inspection

Online: 8 June 2023 (08:16:00 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202306.0605.v1

Synthesis and Evaluation of 99mTc-labeled PSMA-targeted Tracers Based on the Lys-urea-Aad Pharmacophore for Detecting Prostate Cancer with Single Photon Emission Computed Tomography

Kelly Lu, Chengcheng Zhang, Zhengxing Zhang, Hsiou-Ting Kuo, Nadine Colpo, François Bénard, Kuo-Shyan Lin

Subject: Medicinal Chemistry, Chemistry And Materials Science Keywords: prostate-specific membrane antigen (PSMA); technetium-99m; single photon emission computed tomography (SPECT); molecular imaging; HYNIC

Online: 8 June 2023 (08:11:15 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202306.0588.v1

Distance Based Analysis of Early Fire Indicators on a New Indoor Laboratory Dataset with Distributed Multi-Sensor Nodes

Pascal Vorwerk, Jörg Kelleter, Steffen Müller, Ulrich Krause

Subject: Safety, Risk, Reliability And Quality, Engineering Keywords: early fire detection; multi sensor network; data driven fire detection; machine learning; public data set

Online: 8 June 2023 (08:04:39 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202306.0597.v1

Cumulative Residual Entropy of the Residual Lifetime of a Mixed System at the System Level

Mohamed Kayid, Mashael A. Alshehri

Subject: Mathematical Physics, Physical Sciences Keywords: coherent system; cumulative residual entropy; Shannon entropy; system signature

Online: 8 June 2023 (08:01:33 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202306.0604.v1

The Role of Photosynthesis Processes in Dynamics of Plant Community

Aleksandr Abakumov, Svetlana Pak

Subject: Applied Mathematics, Computer Science And Mathematics Keywords: Mathematical model; differential equations; phytoplankton; photosynthesis; chlorophyll; optimal control problem

Online: 8 June 2023 (08:00:38 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202306.0603.v1

Assessing Last Decimal Digits in Retracted Research Articles: Accounting for Missing Zeroes

Walter Richard Schumm

Subject: Sociology, Social Sciences Keywords: Scientific misconduct; fraud; regression digits; zeroes; Eric Stewart; fabrication of results

Online: 8 June 2023 (07:42:55 CEST)

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Preprint REVIEW | doi:10.20944/preprints202306.0602.v1

Molecular Mechanisms for Targeting Metastatic Cancer Cells and to Overcome or Prevent Chemotherapy Resistance

Maryam Eslami, Ali Davarpanah, Amir Hossein Rismanbaf, Farzad Taghizadeh-Hesary, Saeed Dorgaleleh, Omeed MemarSadeghi, Karim Nayernia, Babak Behnam

Subject: Oncology And Oncogenics, Medicine And Pharmacology Keywords: Chemotherapy Resistance; Molecular Targeting; Signalling Pathway; Metastasis; Apoptosis; Tumor Microenvironment; Cancer Stemness

Online: 8 June 2023 (07:37:41 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202306.0596.v1

Nanoparticle Size and Heat Pipe Angle Impact on Thermal Effectiveness of a Cylindrical Screen Mesh Heat Pipe.

Ratchagaraja Dhairiyasamy

Subject: Mechanical Engineering, Engineering Keywords: Heat pipe, Particle size, Heat transfer, Thermal conductivity, Heat transfer coefficient

Online: 8 June 2023 (07:36:33 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202306.0592.v1

Anti-inflammatory and Antioxidant Potential of Pteropodine in Rodents

Rogelio Paniagua-Pérez, Laura Sánchez-Chapul, Eduardo Madrigal-Bujaidar, Isela Álvarez-González, Eduardo Madrigal-Santillán, Lidia Cruz-Hernández, Carlos Matínez-Canseco, Celia Reyes-Legorreta, Lidia Ruíz-Rosano, Cecilia Hernández-Flores, Rene Valdez-Mijares, Alejandra Quintana-Armenta

Subject: Toxicology, Biology And Life Sciences Keywords: anti-inflammatory assays; murine model; rodent-induced edema

Online: 8 June 2023 (07:34:51 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202306.0598.v1

Framework for Simulation Study Involving Volatility Estimation: The GARCH Approach

Richard T. A. Samuel, Charles Chimedza, Caston Sigauke

Subject: Probability And Statistics, Computer Science And Mathematics Keywords: bias; consistency; efficiency; simulation design; volatility estimation

Online: 8 June 2023 (07:31:27 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202306.0569.v1

A Model of Triage of Serious Spinal Pathologies and Therapeutic Options Based on a Delphi Study

Philippe Meidinger, Amélie Kéchichian, Nicolas Pinsault

Subject: Physical Therapy, Sports Therapy And Rehabilitation, Public Health And Healthcare Keywords: red flags; clinical reasoning; back pain; cauda equina syndrome; spinal fracture; spinal infection; malignancy; serious pathology; Spinal pain; low back pain; diagnostic triage

Online: 8 June 2023 (07:25:53 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202306.0600.v1

Quantification on Non-Motor Symptoms in Parkinsonian Cynomolgus Monkeys

Yu Bao, Chaoning Gan, Zuyue Chen, Zhongquan Qi, Zhiqiang Meng, Feng Yue

Subject: Aging, Biology And Life Sciences Keywords: Parkinson; monkey; non-motor symptoms; anxiety; sleep; cognition

Online: 8 June 2023 (07:25:45 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202306.0599.v1

Occurrence, Structure and Abundance Natural and Artificial of Juglans neotropica Diels, in the Province of Loja and Zamora Chinchipe in Southern Ecuador

Byron Palacios Herrera, Santiago Pereira Lorenzo, Darwin Pucha Cofrep

Subject: Environmental Science, Environmental And Earth Sciences Keywords: Genetics; forest; ecosystem; wood; native; extinction

Online: 8 June 2023 (07:13:55 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202306.0595.v1

Analysis of Passive Strategies in Traditional Vernacular Architecture

Pedro Moscoso-García, Andrés Cárdenas-Sánchez, Felipe Quesada-Molina

Subject: Architecture, Arts And Humanities Keywords: Vernacular housing; passive design strategies; indoor thermal environment; building energy performance; dynamic thermal simulations

Online: 8 June 2023 (05:17:24 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202306.0594.v1

Monitoring Braided River-Bed Dynamics at Sub-Event Time Scale Using Time Series of Sentinel-1 SAR Imagery

Daniele Rossi, Guido Zolezzi, Walter Bertoldi, Alfonso Vitti

Subject: Remote Sensing, Environmental And Earth Sciences Keywords: SAR; Gravel-bed rivers; Morphodynamics; Flood dynamics; River bank erosion

Online: 8 June 2023 (05:00:07 CEST)

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Remote sensing plays a central role in the assessment of environmental phenomena and has increasingly become a powerful tool for monitoring shorelines, rivers morphology, flood waves delineation and floods assessment. Optical based monitoring and characterization of river evolution at long time scales is a key tool in fluvial geomorphology. However, the evolution occurring during extreme events is crucial for the understanding of the river dynamics under severe flow conditions and requires the processing of data from active sensors to overcome cloud obstructions. This work proposes a cloud-based unsupervised algorithm for the intra-event monitoring of river dynamics during extreme flow conditions based on time series of Sentinel-1 SAR data. The method allows the extraction of multi-temporal series of spatially explicit geometric parameters at high time and spatial resolutions, linking them to the hydrometric levels acquired by reference gauge stations. Intra-event reconstruction of inundation dynamics has led to the estimation of the relationship between hydrometric level and wet area extension and the assessment of bank erosion phenomena. Time series of SAR acquisitions, provided by Copernicus Sentinel-1 satellites, were analyzed to quantify changes in the wet area of a reach of the Tagliamento river under different flow conditions. The algorithm, developed within the Python-API of GEE, first empowers the Sentinel-1 images with the hydrometric level, then involves radiometric slope correction and speckle noise filtering. The Otsu method is then used for image segmentation leading to a water and dry land binary classification. Results support many types of analysis about river dynamics, including morphological changes, floods monitoring and relief efforts and bio-physical habitat dynamics. The results encourage future advancements and applications of the algorithm, specifically exploring SAR data from ICEYE and Capella Space constellations, which offer significantly higher spatial and temporal resolutions compared to Sentinel-1 data.

Preprint ARTICLE | doi:10.20944/preprints202306.0593.v1

Baby Swimming: Environment & Equipment

Carlos Santos, Carolina Burnay, Carla Cruz, David I. Anderson, Rita Cordovil

Subject: Public Health And Health Services, Public Health And Healthcare Keywords: Physical features; task constrains; aquatic activities; child development

Online: 8 June 2023 (04:57:01 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202306.0591.v1

Enhanced Energy Storage Performance and Efficiency in Bi0.5(Na0.8K0.2)0.5TiO3–Bi0.2Sr0.7TiO3 Relaxor Ferroelectric Ceramics via Domain Engineering

Srinivas Pattipaka, Hyunsu Choi, Yeseul Lim, Kwi-Il Park, Kyeongwoon Chung, And Geon Tae Hwang

Subject: Electrical And Electronic Engineering, Engineering Keywords: Lead-free ceramic capacitors; Dielectric; Relaxor ferroelectric; Domain engineering; Energy storage

Online: 8 June 2023 (04:52:57 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202306.0587.v1

Development of Clause Complexity in Children with Specific Language Impairment/Language Development Disorder. A Longitudinal Study

Claudia Araya, Carmen Julia Coloma, Camilo Quezada, Paula Benavente

Subject: Language And Linguistics, Social Sciences Keywords: Grammar; clause complexity; longitudinal study; Specific Language Impairment (SLI); Developmental Language Disorder (DLD).

Online: 8 June 2023 (04:41:09 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202306.0574.v1

Strategies of Screening and Treating Post-extubation Dysphagia: An Overview of the Situation in Greek-Cypriot ICUs

Meropi Mpouzika, Stelios Iordanou, Maria Kyranou, Katerina Iliopoulou, Stelios Parissopoulos, Maria Kalafati, Elizabeth Papathanassoglou

Subject: Clinical Medicine, Medicine And Pharmacology Keywords: assessment; awareness; diagnosis; dysphagia; intensive care; management; screening; treatment; practices

Online: 8 June 2023 (04:39:36 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202306.0590.v1

Highly Efficient All-Solution Processed Quantum Dot Light-Emitting Diodes Using MoO3 Nanoparticle Hole Injection Layer

Ji-Hun Yang, Gyeong-Pil Jang, Su-Young. Kim, Young-Bin Chae, Kyoung-Ho Lee, Chang-Kyo Kim

Subject: Electrical And Electronic Engineering, Engineering Keywords: quantum dot light-emitting diode; solution process; MoO3 nanoparticles; hole injection layer; charge balance

Online: 8 June 2023 (04:38:03 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202306.0589.v1

Adsorption of Hydrogen Sulphide on Activated Carbon Materials Derived from the Solid Fibrous Digestate

Evangelia Choleva, Anastasios Mitsopoulos, Georgia Dimitropoulou, George Em. Romanos, Evangelos P. Kouvelos, Georgios Pilatos, Stylianos D. Stefanidis, Angelos Lappas, Themistoklis Sfetsas

Subject: Other, Environmental And Earth Sciences Keywords: activated carbon; hydrogen sulfide; biogas; physical adsorption; micropores; biogas; solid fibrous digestate; carbon dioxide; mesopores

Online: 8 June 2023 (04:31:16 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202306.0585.v1

A High Performance and Robust FPGA Implementation of a Driver State Monitoring Application

Panagiotis Christakos, Nikos Petrellis, Panagiotis Mousouliotis, George Keramidas, Christos Antonopoulos, Nikolaos Voros

Subject: Artificial Intelligence And Machine Learning, Computer Science And Mathematics Keywords: Shape Alignment; Driver Drowsiness; Face Detection Validity; Machine Learning; Hardware Acceleration; Vitis HLS

Online: 8 June 2023 (04:21:58 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202306.0586.v1

Harbor Porpoise Aggregations in the Salish Sea

Dave Anderson, Laurie Shuster, Cindy R. Elliser, Katrina MacIver, Erin Johns Gless, Johannes Krieger, Anna Hall

Subject: Ecology, Evolution, Behavior And Systematics, Biology And Life Sciences Keywords: harbor porpoise; aggregation; social behavior; Phocoena phocoena; foraging behavior; large group; transboundary; community science; Salish Sea

Online: 8 June 2023 (04:18:24 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202306.0584.v1

Flowered Grain Quality and Phytochemical Content of Non-Conventional Maize Hybrids from the Mexican Subtropics in Three Crop Cycles

Leticia García-Cruz, María Gricelda Vázquez-Carrillo, Ricardo Ernesto Preciado-Ortiz

Subject: Food Chemistry, Chemistry And Materials Science Keywords: Elotes Occidentales; total anthocyanin; total soluble phenols; volume of flowered grain.

Online: 8 June 2023 (04:16:11 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202306.0583.v1

Cosmetics Pattern Map Considering their Effects on Skin Microbiota-Principal Component Analysis of the Effects on Short Chain Fatty Acid Production by Skin Microbiota Staphylococcus epidermidis

Kurumi Tanabe, Chihiro Moriguchi, Nao Fujiyama, Yuka Shigematsu, Nanami Haraguchi, Yuto Hirano, Huanghuang Dai, Shigeki Inaba, Yoshihiro Tokudome, Hiroshi Kitagaki

Subject: Dermatology, Medicine And Pharmacology Keywords: cosmetics; skin microbiota; Staphylococcus epidermidis; lactic acid; PCA

Online: 8 June 2023 (04:09:58 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202306.0582.v1

Kampus Mengajar, a Form of Direct Student Service in the World of Education?

Michael Revelin Ervan Septian

Subject: Education, Social Sciences Keywords: Kampus Mengajar; MBKM; Students; Education; Dhaniswara Junior High School Surabaya

Online: 8 June 2023 (04:06:11 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202306.0581.v1

Propagation of Terahertz Surface Plasmon Pulses in a Plasmonic Fiber

Nikolai I. Petrov

Subject: Applied Physics, Physical Sciences Keywords: plasmonic fiber; dielectric coating; THz surface plasmon waves; dispersive propagation, chirped signal

Online: 8 June 2023 (04:01:07 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202306.0580.v1

Development and Performance Evaluation of Low Cost 2WT Operated Earthing Up Machine for Sugarcane Cultivation in Bangladesh

Md. Nafiul Ferdows Sifat, Dr. Md. Anisur Rahman, Md. Rostom Ali, Md. Abu Hanif, Sayed Shams Tabriz, Mohammad Sanowar Hossen, Md. Rokonuzzaman

Subject: Agricultural Science And Agronomy, Biology And Life Sciences Keywords: Sugarcane cultivation; development; 2WT; earthing up machine; economic performance

Online: 8 June 2023 (04:01:00 CEST)

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Like the most of crops, especially sugarcane needs to be kept upright until it is harvested. Because, lodging of sugarcane has a significant negative effect on cane yield and sugar content of sugarcane. To keep sugarcane upright earthing up is an utmost intercultural operation. In Bangladesh, most of the operations for sugarcane cultivation including earthing up are generally done in traditional method using human labor which increases production costs as well as reduces the income of sugarcane growers. So, a cost effective two-wheeled tractor (2WT) mounted earthing up machine was developed in Bangladesh Sugarcrop Research Institute (BSRI), Pabna to reduce drudgery and cost of sugarcane production. Field tests were conducted in experimental sugarcane field at BSRI and technical and economic performances of the developed earthing up machine were also carried out based on the field test. Average effective field capacity and field efficiency were found 0.16 ha/hr and 77.41 %, respectively for the developed earthing up machine. The earthing up machine was not found economically viable when it is used only for earthing up operation. Besides, when the 2WT was being used as the main driver for other activities including earthing up operation, then the earthing up machine becomes economically beneficial with net cash flow, net present value, internal rate of return, benefit-cost ratio and payback period of BDT 148497/ha, BDT 23184, 3%, 3.81:1 and approximately 1 year, respectively. On the contrary, considering cost of only earthing up tool without 2WT, then it was found economically beneficial with net cash flow, internal rate of return, net present value, benefit-cost ratio and payback period of BDT 16428/ha, BDT 3053, 4.7%, 2.71:1 and approximately 2 years, respectively. Since 2WT is commonly used for versatile farming purposes. Therefore, versatile use of 2WT as prime mover for other machines including earthing up machine can make earthing up machine economically viable and beneficial for sugarcane growers.

Preprint ARTICLE | doi:10.20944/preprints202306.0579.v1

Haematological Profile of Hb Adana Among High School Students in Northeast of Peninsular, Malaysia

Lee Miin Phoon, Mat Jusoh Siti Asmaa, Nur Atikah Zakaria, Suryati Hussin, Rosnah Bahar, Mohd Nazri Hassan, Zefarina Zulkafli, Salfarina Iberahim, Marne Abdullah, Noor Haslina Mohd Noor, Shafini Mohd Yusoff, Marini Ramli

Subject: Hematology, Medicine And Pharmacology Keywords: Hb Adana; non-deletional α-thalassaemia; Hb Constant Spring; HbE

Online: 8 June 2023 (03:58:49 CEST)

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Hb Adana is a non-deletional α-thalassaemia variant, due to mutations in α1- or α2-globin codon 59 (αCD59) that produce unstable α-globin. Clinical appearance can range from silent carrier to blood transfusion reliance, hepatosplenomegaly, skeletal deformities, and spinal cord compression. Despite the importance of Hb Adana inheritance, this Hb variant is challenging to study since molecular tests are scarce and routine diagnosis can be missed. This study explored the distribution of Hb Adana among local high school students and evaluate the hematological parameters and haemoglobin analysis of Hb Adana in this region of Malaysia. This retrospective study included 13,721 blood samples from high school students enrolled in Malaysia's National Thalassaemia Screening Program at Hospital Raja Perempuan Zainab II (HRPZ II). Multiplex Gap PCR was used to detect deletional α-thalassaemia. Common non-deletional α-thalassaemia was detected using multiplex ARMS PCR. Evaluable data were retrieved from the HRPZ II database. Results: A total of 2327 subjects exhibited common deletional (n=1037, 44.6%) and non-deletional (n=1290, 55.4%) α-thalassaemia. Hb Constant Spring was the most frequent non-deletional α-thalassaemia. Thirty-one participants (1.33%) had αCD59α/αα and one (0.04%) had αCD59α/-α3.7. The 32 Hb Adana subjects were 87.5% Malay, and 12.5% Orang Asli. Additionally, seven cases of HbE/Hb Adana were discovered. The haemoglobin level in heterozygous Hb Adana ranged from mild anaemia to normal, 95.0 g/L to 153.0 g/L. The MCV and MCH were approximately 73 fL and 23 pg, respectively. Conclusions: We have denoted the distribution of alpha thalassaemia mutation patterns among high school students in Kelantan, Northeast Peninsular of Malaysia. Our observation showed Hb Adana was rarely uncommon in our region and the co-inheritance with an α-gene deletion generates α+-thalassaemia; with HbE, α0-thalassaemia. All heterozygous Hb Adana exhibited low MCVs and MCHs.

Preprint CONCEPT PAPER | doi:10.20944/preprints202306.0578.v1

An Outline of a Conceptual Framework for Contemporary Biological Systematics

Igor Ya. Pavlinov

Subject: Other, Biology And Life Sciences Keywords: contemporary conceptualism; cognitive situation; biological systematics; philosophy of systematics; taxonomic theory; taxonomic monism & pluralism; taxonomic nomenclature

Online: 8 June 2023 (03:51:46 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202306.0577.v1

A Low Latency, Low Jitter Retimer Circuit for PCIe 6.0

Qing Liu, Heming Wang, Fangxu Lyu, Geng Zhang, Dongbin Lyu

Subject: Electrical And Electronic Engineering, Engineering Keywords: PCIe 6.0; SerDes; low latency,; low jitter; Retimer

Online: 8 June 2023 (03:39:58 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202306.0476.v2

Diurnal Variation of and Optimal Time To Measure Holter-Based Late Potentials To Predict Lethal Arrhythmia After Myocardial In-Farction

Kenichi Hashimoto, Naomi Harada, Motohiro Kimata, Yusuke Kawamura, Naoya Fujita, Akinori Sekizawa, Yosuke Ono, Yasuhiro Obuchi, Tadateru Takayama, Yuji Kasamaki, Yuji Tanaka

Subject: Cardiac And Cardiovascular Systems, Medicine And Pharmacology Keywords: Late potentials; signal-averaged electrocardiogrhy; heart rate variability; fatal arrhyrthmia; sudden cardiac death

Online: 8 June 2023 (03:37:05 CEST)

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Abstract: Background and Objectives: Holter-based late potentials (LPs) are useful for predicting lethal arrhythmias in organic cardiac diseases. Although Holter-based LPs exhibit diurnal varia-tion, no studies have evaluated the optimal timing of LP measurement over 24 h for predicting lethal arrhythmia that leads to sudden cardiac death. Thus, this study aimed to validate the most effective timing for Holter-based LP testing and to explore factors influencing diurnal variability of LP parameters. Materials and Methods: We retrospectively analyzed 126 patients with post-myocardial infarction (MI) status and 60 control participants who underwent high-resolution Holter electrocardiography. Among the 126 post-MI patients, 23 developed sustained ventricular tachycardia (VT) (the MI-VT group), while 103 did not (the MI-non-VT group) during the obser-vation period. Holter-based LPs were measured at 0:00, 4:00, 8:00, 12:00, 16:00, and 20:00, and heart rate variability analysis was simultaneously performed to investigate factors influencing diurnal variability of LP parameters. Results: Holter-based LP parameters showed diurnal variation with significant deterioration at night and improvement during the day. Assessment at the time with the longest duration of low-amplitude signals <40 μV in the filtered QRS complex terminus (LAS40) gave the highest receiver operating characteristics curve (area under the curve, 0.659) and the highest odds ratio (3.75; 95% confidence interval, 1.45–9.71; p=0.006) for predicting VT. In the multiple regression analysis, heart rate and noise were significant factors affecting LP parameters in the MI-VT and control groups. In the non-VT group, LP parameters were significantly influenced by noise and parasympathetic heart rate variability parameters such as logPNN50. Conclusions: For Holter-based LP measurements, test accuracy was higher when LP was measured at the time of the highest or worst value of LAS40. Changes in autonomic nervous system activity, including heart rate and noise levels, were factors influencing diurnal variability.

Preprint CASE REPORT | doi:10.20944/preprints202306.0576.v1

Recurrent Transient Global Amnesia: Pathogenic Insights From Chronobiology?

Andrew Larner

Subject: Neuroscience And Neurology, Medicine And Pharmacology Keywords: TGA; recurrence; chronobiology

Online: 8 June 2023 (03:32:28 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202306.0573.v1

Experimental Investigation of Convective Drying of Ginger Rhizomes Using the Environmental Stress Chambers and Linear Heat Conduction

Joshua Adeniyi Depiver, Sabuj Mallik

Subject: Agricultural Science And Agronomy, Biology And Life Sciences Keywords: Ginger Rhizomes; Moisture Content; Thermal Conductivity; Forced Convection; Drying Temperature

Online: 8 June 2023 (03:25:06 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202306.0572.v1

Component Criticality Analysis for Improved Ship Machinery Reliability

Abdullahi Abdulkarim Daya, Iraklis Lazakis

Subject: Marine Engineering, Engineering Keywords: Marine Diesel Generator; reliability importance measures; fault identification; critical compo-nents; performance

Online: 8 June 2023 (03:21:11 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202306.0571.v1

AIMS: An Automatic Semantic Machine Learning Microservice Framework to Support Biomedical and Bioengineering Research

Hong Qing Yu, Sam O'Neill, Ali Kermanizadeh

Subject: Artificial Intelligence And Machine Learning, Computer Science And Mathematics Keywords: AI automation; Biomedical; Machine learning; Microservices; Knowledge Graph; Semantic Web Services

Online: 8 June 2023 (03:17:33 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202306.0289.v2

Item-Oriented Personalized LDP for Discrete Distribution Estimation

Xin Li, Hong Zhu, Zhiqiang Zhang, Meiyi Xie

Subject: Other, Computer Science And Mathematics Keywords: Discrete distribution estimation; Local differential privacy; Item-oriented personalization; Randomized response

Online: 8 June 2023 (03:16:47 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202306.0570.v1

A decision feedback equalization algorithm based on simplified Volterra structure for PAM4 IM-DD optical communication system

Yao Xie, Peili He, Wei Li, Na Li

Subject: Other, Engineering Keywords: optical fiber data communication system; EML; PAM4; Volterra; DFE

Online: 8 June 2023 (03:00:45 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202306.0568.v1

Oil Extraction From Spent Coffee Grounds As Green Corrosion Inhibitor for Copper in 3 wt% NaCl Solution

Ghada ROUIN, Fatma MASMOUDI, Makki ABDELMOULEH, Mohamed MASMOUDI

Subject: Electrochemistry, Chemistry And Materials Science Keywords: Corrosion; copper; spent coffee grounds; voltammetry around OCP; EIS

Online: 8 June 2023 (02:25:06 CEST)

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Preprint REVIEW | doi:10.20944/preprints202306.0567.v1

Stable Coronary Artery Disease: Who Finally Benefits from Coronary Revascularization in the Modern Era? The ISCHEMIA and Interim ISCHEMIA-EXTEND Analysis

Leonid L Bershtein, Alexey Sumin, Elizaveta Zbyshevskaya, Victoria Gumerova, Darejan Tsurtsumia, Igor Kochanov, Alina Andreeva, Vartan Piltakian, Sergey Sayganov

Subject: Cardiac And Cardiovascular Systems, Medicine And Pharmacology Keywords: chronic coronary syndromes; revascularization; prognosis; ISCHEMIA; ISCHEMIA-EXTEND

Online: 8 June 2023 (02:13:16 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202306.0566.v1

On the Applicability of Modified Water Based Ysz Suspensions to Produce Plasma Sprayed Columnar Coatings

Amirhossein Yaghtin, Maryam Yaghtin, Pooria Najafisayar, Zhaolin Tang, Tom Troczynski

Subject: Metallurgy And Metallurgical Engineering, Engineering Keywords: YSZ suspension; Water; Ethanol; Plasma Spraying; Columnar coating

Online: 8 June 2023 (02:10:01 CEST)

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Preprint REVIEW | doi:10.20944/preprints202306.0565.v1

An Extensive Approach Towards Engineering Design of Sewage Plants in China

Abdulmoseen Segun Giwa, Nasir Ali

Subject: Chemical Engineering, Engineering Keywords: Engineering design; Landscape design; Underground sewage treatment environmental pollutions.

Online: 8 June 2023 (02:00:26 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202306.0564.v1

A Sustainable Green Synthesize of Nanocomposite of Silver Nanoparticles Functionalized with Pectin using Carpesium nepalense for Different Therapeutic Application: A Mechanistic Approach

Samiullah Burki, Muhammad Arif Asghar, Imdad Ali, Muhammad Asif Asghar, Zeba Gul Burki, Ibrahim Javed, Riaz Ullah

Subject: Medicinal Chemistry, Chemistry And Materials Science Keywords: Green Synthesis; Pectin functionalized silver nanoparticles; Antibacterial activity; Hepatoprotective

Online: 7 June 2023 (14:22:20 CEST)

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Preprint REVIEW | doi:10.20944/preprints202306.0563.v1

Transparent Self-cleaning Coatings: A Review

Pengyuan Wu, Zhuanzhuan Xue, Tianxiang Yu, Oleksiy V. Penkov

Subject: Materials Science And Technology, Chemistry And Materials Science Keywords: self-cleaning coatings; wettability; durability; mechanical properties; prepare methods

Online: 7 June 2023 (13:41:50 CEST)

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Advanced coatings are essential to modern technologies, as they optimise surface characteristics for different application scenarios. Transparent and self-cleaning coatings are increasingly used as protective coatings for various applications, such as foldable touchscreens, windows, and solar panels. Moreover, incorporating other functionalities such as high hardness, wear resistance, and flexibility into transparent and self-cleaning coatings is important for broadening the use cases. Although many kinds of multifunctional coatings have been developed, it is still difficult to embody several properties in one coating adequately, as some properties, such as hardness and flexibility, are inherently contrastive. This review first describes basic principles, including wetting ability, photocatalytic reactions, photo-induced hydrophilic phenomena, and the implication of self-cleaning. The desired properties of multifunctional coatings are then listed, and methods for evaluating different properties are used. Recent progress in various preparation methods for multifunctional coatings, including the sol-gel, dip/spin, and chemical vapour deposition (CVD) methods, are also presented. Magnetron sputtering (MS) technology is widely used in coating preparation. Compared with chemosynthesis and CVD, MS is time-saving, suitable for industrial production, and environmentally friendly. Coatings prepared by MS usually possess excellent mechanical properties. Thus, we highlight the current research status of MS technology in multifunctional coating preparation. Moreover, according to the multilayer design structure of coatings, their optical and mechanical properties and self-cleaning ability can be controlled by combining the characteristics of different materials. Finally, combining photocatalytic materials such as TiO2 with other materials through a multilayer structure to obtain a multifunctional coating with excellent overall properties is discussed.

Preprint ARTICLE | doi:10.20944/preprints202306.0562.v1

Silica Fume Improves the Frost Resistance of Alkali-activated Slag/fly Ash Geopolymer Binder

Sen Wang, Yuqing Liang, Duosi Mo, Chonghui Zhang, Jiwei Xue, Xuewen Song, Yachao Wang

Subject: Materials Science And Technology, Chemistry And Materials Science Keywords: alkali-activated; freezing-thawing; fly ash; geopolymer; silica fume

Online: 7 June 2023 (13:34:14 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202306.0561.v1

Integration of Indigenous and Local Knowledge in Policy and Practice of Nature-based Solutions in China: Progress and Highlights

Ruizi Yu, Quan Mu

Subject: Other, Environmental And Earth Sciences Keywords: nature-based solutions; indigenous and local knowledge; China

Online: 7 June 2023 (13:26:17 CEST)

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Preprint BRIEF REPORT | doi:10.20944/preprints202306.0560.v1

Pion-Argon Inclusive Cross-Section Measurement on ProtoDUNE-SP

Yinrui Liu

Subject: Nuclear And High Energy Physics, Physical Sciences Keywords: ProtoDUNE-SP; hadron beam; liquid argon; cross-section

Online: 7 June 2023 (13:24:19 CEST)

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Preprint REVIEW | doi:10.20944/preprints202306.0559.v1

Cartilage Conduction Hearing Aids in Clinical Practice

Tadashi Nishimura, Hiroshi Hosoi, Ryota Shimokura, Tadashi Kitahara

Subject: Otolaryngology, Medicine And Pharmacology Keywords: Bone conduction; Cartilage conduction; Hearing device; Amplification; Aural atresia; Canal stenosis; Conductive hearing loss; Chronic otitis media

Online: 7 June 2023 (13:22:41 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202202.0254.v2

Minimum Uncertainty as Bayesian Network Model Selection Principle

Grigoriy Gogoshin, Andrei Rodin

Subject: Applied Mathematics, Computer Science And Mathematics Keywords: Bayesian Networks; probabilistic networks; conditional independence; model selection criteria; mutual information; sampling error; statistical uncertainty; MDL; BIC; AIC; BD; tRNA

Online: 7 June 2023 (13:20:18 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202306.0558.v1

Ductile effect of PGA/PCL Blending Plastics using Novel Ionic Chain Extender with Non-Covalent Bonds

Hyuk Jun Kwon, Joseph Jang, Won-Gun Koh, Jun-Young Lee, Kiseob Hwang

Subject: Polymers And Plastics, Chemistry And Materials Science Keywords: Ionic chain extender; Non-covalent bonds; Ductility; Polyglycolic acid; Blending plastics

Online: 7 June 2023 (13:16:49 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202306.0557.v1

Study of Viral Coinfection of the Ixodes Persulcatus Tickets Feeding on Humans in a Natural Foci of the South of the Far East

Galina Leonova, Larisa Somova, Svetlana Abramva, Evgeniy Pustovalov

Subject: Virology, Biology And Life Sciences Keywords: coinfection; tick Ixodes persulcatus; virus isolate; tick-borne encephalitis virus (TBEV); ectromelia virus; biological properties of co-isolate; electron microscopy; south of the Russian Far East

Online: 7 June 2023 (13:14:24 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202306.0556.v1

Image Data Extraction and Driving Behavior Analysis Based on Geographic Information and Driving Data

Huei-Yung Lin, Jun-Zhi Zhang, Chin-Chen Chang

Subject: Artificial Intelligence And Machine Learning, Computer Science And Mathematics Keywords: image data extraction; driving behavior analysis; geographic information system; global position system

Online: 7 June 2023 (13:09:43 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202306.0555.v1

Exploration of a Filtration Model Variable Space using Machine Learning

Jeffrey Belding, Deena Hannoun

Subject: Water Science And Technology, Environmental And Earth Sciences Keywords: Filtration, Water Treatment, Water Management, Machine Learning, Run-to-Run Control

Online: 7 June 2023 (13:07:38 CEST)

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Preprint REVIEW | doi:10.20944/preprints202306.0554.v1

Current Treatment Approach, Emerging Therapies and New Horizons in Systemic Lupus Erythematosus

Panagiotis Athanassiou, Lambros Athanassiou

Subject: Immunology And Allergy, Medicine And Pharmacology Keywords: systemic lupus erythematosus; treatment; hydroxychloroquine; corticosteroids; biologic agents; belimumab; rituximab; anifrolumab; tocilizumab; baricitinib

Online: 7 June 2023 (13:04:07 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202306.0553.v1

Numerical Simulation of Sediment Transport in Unsteady Open Channel Flow

Jennifer G. Duan, Chunshui Yu, Yan Ding

Subject: Civil Engineering, Engineering Keywords: Dam-break flow; Godunov-type finite volume method; HLLC Riemann solver; Nonequilibrium sediment transport model; Variable density shallow water equations; Well-balanced property

Online: 7 June 2023 (12:57:32 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202306.0552.v1

Building Ensemble of Resnet for Dolphin Whistle Detection

Loris Nanni, Daniela Cuza, Sheryl Brahnam

Subject: Artificial Intelligence And Machine Learning, Computer Science And Mathematics Keywords: Convolutional Neural Network; dolphin whistle; ensemble; spectrogram classification

Online: 7 June 2023 (12:54:44 CEST)

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Preprint BRIEF REPORT | doi:10.20944/preprints202306.0463.v2

Plastid Genome of Passiflora tripartita var. mollissima (poro-poro) from Huánuco, Peru

Flavio Aliaga, Mario Zapata-Cruz, Silvia Ana Valverde-Zavaleta

Subject: Biology And Life Sciences, Plant Sciences Keywords: Chloroplast genome; Passifloraceae; Passiflora tripartita; poro-poro; Huánuco; Peru

Online: 7 June 2023 (12:23:59 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202306.0551.v1

Detection of Brain Tissue Damage in CO Poisoning with a New Method

Sedat Ozbay, Mustafa Ayan, Recep Eroz, Ayhan Saritas

Subject: Medicine And Pharmacology, Neuroscience And Neurology Keywords: Argyrophilic Nucleolus Organizer Region; Hypoxia; Brain; Carbon Monoxide Poisoning; Marker

Online: 7 June 2023 (12:11:19 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202306.0550.v1

A Change in Global Sagittal Alignment after Transforaminal Epidural Steroids Injections in Lumbar Spinal Stenosis

Park Manakul, Koopong Siribumrungwong, Naphakkhanith Dhanachanvisith

Subject: Medicine And Pharmacology, Orthopedics And Sports Medicine Keywords: Global sagittal balance; Transforaminal epidural steroids injections; Lumbar spinal stenosis

Online: 7 June 2023 (12:10:35 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202306.0549.v1

Hydraulic Response and Overtopping Performance of Single-Layer Double-Cube Unit Armored Mound Breakwater

Iman Safari, Dominique Mouazé, Soroush Aliasgary, Guillaume Carpentier, François Ropert

Subject: Engineering, Marine Engineering Keywords: Armor unit; Hydraulic Stability; Hydraulic performance; Turbulence; Roughness; Marine structures

Online: 7 June 2023 (12:07:44 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202306.0548.v1

Suppression of NASH-Related HCC by Farnesyltransferase Inhibitor Through Inhibition of Inflammation and Hypoxia-Inducible Factor-1α Expression

Kohei Yamada, Tomokazu Tanaka, Keita Kai, Shohei Matsufuji, Kotaro Ito, Yoshihiko Kitajima, Tatsuya Manabe, Hirokazu Noshiro

Subject: Medicine And Pharmacology, Gastroenterology And Hepatology Keywords: non-alcoholic steatohepatitis; hepatocellular carcinoma; farnesyltransferase inhibitor; hypoxia-inducible factor-1α; anti-inflammatory response; nuclear factor-κB; transforming growth factor-β; Warburg effect; reactive oxygen species; interleukin-6

Online: 7 June 2023 (12:05:28 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202306.0547.v1

Structural & Tectonic Evolution of the Porgera Gold Mine; Highlands of Papua New Guinea

Kevin C. Hill, Gareth T. Cooper, Agnes Pokondepa, Peter Essy, Thiwaporn Phonsit, Mark Haydon

Subject: Environmental And Earth Sciences, Geophysics And Geology Keywords: Fold belt; Metasediments; Ore-body; Orogenesis; Pull-apart basin

Online: 7 June 2023 (11:57:26 CEST)

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The acquisition of regional, 1 metre resolution LIDAR in the PNG Highlands combined with 3D modelling in MoveTM has revolutionized our understanding of the evolution of the Porgera gold mine and areas of new potential. The new 3D model demonstrates active pull-apart basins along a regional transfer during ongoing fold and thrust deformation. When overlain on regional aeromagnetic data, new potential is revealed. The Porgera gold mine is one of the richest in the world and lies in a wide valley at an elevation of 2800m surrounded by mountains up to 4000m high in the middle of the PNG Highlands. It lies along a major lineament, the Porgera Transfer Zone (PTZ), cutting across the orogen that is associated with a 50 km offset of the ophiolite belt. To the NW of the mine there is an extensive belt of low- to high-grade metasediments that formed in deep water during Jurassic rifting, but were metamorphosed during Eocene subduction to the north. Subduction ceased due to accretion of the Sepik Terrane which caused inversion and mild erosion of the Porgera area. The Late Oligocene onset of wrenching in the Mobile Belt to the north placed that area into extension, emplacing metamorphic core complexes, and led to regional subsidence in the Early Miocene. Collision of the margin with the Melanesian Arc in the Middle Miocene caused Late Miocene to Pliocene orogenesis creating the broad mountain belt that we see today, that is still active, as shown by the 2018 MW 7.5 earthquake. Regional mapping of the area using high resolution LIDAR in association with limited field mapping, analysis of gravity and magnetics data and drilling of 300-500m deep core-holes has allowed development of a detailed 3D structural model. The Porgera valley is constrained laterally by the Eastern Boundary and Western Boundary dextral strike-slip faults that lie along the PTZ cutting across the orogeny. However, whilst the position and nature of the faults is clear, due to bending, fracturing and offset of major synclines and anticlines, the faults do not crop-out as significant through-going features. Rather, the dextral offset of basement is soft-linked to the Tertiary limestones at surface due to intervening thick, ductile Cretaceous shales. Fold and thrust structures are ubiquitous in the Tertiary limestones, but the youngest structural features are large extensional faults, particularly around the Porgera valley. The intrusive underlying the Porgera ore-body was emplaced at 6.0+-0.3 Ma, the time of maximum compression during orogenesis. At this time the Eastern Boundary fault and Western Boundary fault were both active allowing a pull-apart basin to form locally along the PTZ at the south-eastern boundary of the Jurassic metasediments. This enabled emplacement of the intrusive. The gold-bearing fluids from the intrusive and metasediments were brought up through the Mesozoic muds to the contact with the Paleogene carbonates where the Porgera ore body was emplaced.

Preprint ARTICLE | doi:10.20944/preprints202306.0546.v1

Improving the Efficiency of Radar Method for Monitoring Oil Spills on the Water Surface through the Use of an Active Antenna Array and Cosecant-squared Pattern

Vadim Anatolievich Shpenst, Artem Alekseevich Khalturin

Subject: Engineering, Control And Systems Engineering Keywords: remote sensing; oil spills; radar; phased active antenna array; cosecant-squared pattern diagram

Online: 7 June 2023 (11:47:17 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202306.0513.v1

A Mathematical Model to Study the Potential Hepatitis B Virus Carriers and Effect of Vaccination Strategies in China

Chuanqing Xu, Yu Wang, Kedeng Cheng, Xin Yang, Xiaojing Wang, Songbai Guo, Maoxing Liu, Xiaoling Liu

Subject: Medicine And Pharmacology, Epidemiology And Infectious Diseases Keywords: HBV; potential HBV carriers; stability analysis; reproduction number; vaccine

Online: 7 June 2023 (11:40:49 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202306.0545.v1

Genetic and Protein Expression Profile of Conjunctival Bleb Hyperfibrosis in Early Failure of Glaucoma Surgery

Elena Millá, Néstor Ventura-Abreu, Cristina Vendrell, Mª Jesús Muniesa, Marta Pazos, Xavier Gasull, Núria Comes

Subject: Medicine And Pharmacology, Ophthalmology Keywords: conjunctival filtration bleb; glaucoma surgery failure; conjunctival fibrosis; gene expression; profibrotic genes; fibrosis biomarker

Online: 7 June 2023 (11:37:28 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202306.0544.v1

Vitamin D Intake, Serum 25-hydroxyvitamin-D (25(OH)D) Levels, and Cancer Risk: a Comprehensive Meta-meta-analysis including Meta-analyses of Randomized Controlled Trials and Observational Epidemiological Studies

Mehmet Emin Arayıcı, Yasemin Basbinar, Hulya Ellidokuz

Subject: Medicine And Pharmacology, Oncology And Oncogenics Keywords: cancer; meta-analysis; vitamin D; mortality; incidence

Online: 7 June 2023 (11:11:20 CEST)

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It is a well-established fact that inadequate Vitamin D (Vit-D) levels have negative effects on the development and progression of malignant diseases, mainly cancer. The purpose of this paper was to elucidate the effects of Vit-D intake and serum 25-hydroxyvitamin-D (25(OH)D) levels on cancer incidence and mortality, the current evidence in this field, and the biases of this evidence using the meta-meta-analysis method. Meta-analyses focusing on Vit-D intake, serum 25(OH)D levels, and cancer risk/mortality were identified. A structured computer literature search was performed in PubMed/Medline, Web of Science (WoS), and Scopus electronic databases using predetermined keyword combinations. Primary and secondary meta-meta-analyses were carried out, combining odds ratios (ORs), risk ratios (RRs), and hazard ratios (HRs) for outcomes reported in selected meta-analyses. A total of 35 eligible meta-analyses assessing the association between Vit-D and cancer incidence and/or mortality were included in this study. In the pooled analysis, higher Vit-D intake and serum 25(OH)D levels were associated with lower cancer risk (OR = 0.93, 95% CI: 0.90-0.96, p < 0.001; OR = 0.80, 95% CI: 0.72-0.89, p < 0.001, respectively) and cancer-related mortality (RR = 0.89, 95% CI: 0.86-0.93, p < 0.001; RR = 0.67, 95% CI: 0.58-0.78, p < 0.001, respectively). When meta-analyses whose primary reports included only randomized controlled trials were pooled, there was no significant association between Vit-D intake and cancer risk (OR = 0.99, 95% CI: 0.97-1.01, p = 0.320). In subgroup analysis, Vit-D consumption was associated with a significant decrease in colorectal and lung cancer incidence (OR = 0.89, 95% CI: 0.83-0.96, p = 0.002; OR = 0.88, 95% CI: 0.83-0.94, p < 0.001, respectively). Taken together, both Vit-D intake and higher 25(OH)D levels may provide remarkable benefits in terms of cancer incidence and mortality, however, careful evaluation according to cancer types is critically important and recommended.