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Preprint ARTICLE | doi:10.20944/preprints202312.0585.v1

Fungal Endophytes: Discovering What Lies within Some of Canada’s Oldest and Most Resilient Grapevines

Shawkat Ali, Harrison Wright, Joey Tanney, Justin Renaud, Mark W. Sumarah

Subject: Agricultural Science And Agronomy, Biology And Life Sciences Keywords: Botrytis; fungal endophytes; grapevines; Diaporthe; small metabolites

Online: 8 December 2023 (10:23:24 CET)

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Preprint ARTICLE | doi:10.20944/preprints202312.0552.v1

Prediction of Risk of Exposure to Ammonia Concentration in Broider Chickens Correlated to the Incidence of Diseases

Leonardo V.S. Barbosa, Nilsa Duarte da Silva Lima, Barros Juliana de S.G., Daniella Jorge De Moura, Fernando Estellés, Adrian Ramón-Moragues, Salvador Sanz Calvet, Aránzazu Villagrá

Subject: Animal Science, Veterinary Science And Zoology, Biology And Life Sciences Keywords: ammonia; machine learning; chicken production

Online: 8 December 2023 (10:22:33 CET)

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The objective of the study was to predict the risk of exposure to ammonia concentration in the production of broiler breeds of slow and fast-growing with low and high production density and correlate with the incidence of health injuries in broiler chickens using a learning machine. Two commercial lines of broiler chicken were used, one with fast-growing (Ross®, slaughter age 42 days) and another with slow-growing (Hubbard®, slaughter age 63 days). All slow-growing birds were housed at a density of 32 kg/m2. Fast-growing birds were housed in two different housing densities: low housing density with a final housing density of 16 kg/m2 and high density with a final housing density of 32 kg/m2. A total of 1250 birds were used in this experiment, 450 of which were fast-growing birds and 800 were slow-growing birds. In each room, 306 birds were randomly distributed in 18 boxes (6 boxes for each treatment and 17 birds per box), each with 3 nipple drinkers and a manual feeder. The dimensions of the high-density boxes were 1 x 1.3 m2 , while the low-density boxes had the same number of animals housed in a larger area, with dimensions of 2 x 1.3 m2 . The remaining 319 birds were housed randomly throughout the room and outside the pens to simulate a commercial production system condition (stock density). All birds were fed with an initial commercial feed from day 1 to day 18 of the experiment, and from day 18 until the end, each breed was fed with different feeds according to their nutritional demands. The following data analysis steps were performed: data selection, pre-processing, transformation, mining, analysis, and, interpretation of results. The classification algorithms, decision tree (J48), SMO (Sequential Minimal Optimization), Naive Bayes, and Multilayer Perceptron were applied to the training and test data sets to build a rule model for predicting ammonia risk levels in broiler chickens. The cross-validation technique was used to parameterize the analysis in all models. From the database of the first phase of analysis, with the classifier to predict the risk condition of ammonia concentration, the Spearman correlation coefficient (ρ, rho), considering the presence of pododermatitis, vision/affected and mucosal injury, which includes assessments of the trachea, bronchi, lungs, eyes, paw injuries, and other injuries. A non-parametric correlation measure was applied to injury incidence data as a function of ammonia risk level (1 and 10 ppm) to correlate injury incidence and ammonia level in the conditions studied. The best predictive model capable of evaluating and obtaining better performance was the Multilayer Perceptron when we considered greater accuracy by the level of risk of exposure to ammonia in the broiler chicken production process, including fast and slow-growing. Birds exposed to higher levels of ammonia concentration have a higher correlation coefficient when the relationship between the variables is strong. The Spearman correlation coefficient shows a stronger association between increased risks of ammonia exposure and the incidence of chicken injuries.

Preprint ARTICLE | doi:10.20944/preprints202312.0555.v1

Mortality Trend of Severe COVID-19 in Under-Vaccinated Population Admitted to ICU in French Amazonia

Severine Matheus, Stéphanie Houcke, Guy Roger Lontsingoula, Nicolas Higel, Abesetou Ba, Fabrice Cook, Cyrille Gourjault, Flaubert Nkontcho, Magalie Demar, Mathieu Nacher, Félix Djossou, Didier Hommel, Dabor RESIERE, Jean Marc Pujo, Hatem Kallel

Subject: Health Policy And Services, Public Health And Healthcare Keywords: COVID-19; delta variant; gamma variant; mortality; French Guiana ; ;

Online: 8 December 2023 (10:21:21 CET)

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Preprint SHORT NOTE | doi:10.20944/preprints202312.0553.v1

4-(diphenylphosphoryl)-1-phenylbutane-1,3-dione

Dmitry Tatarinov, Elisa Bajnazarova, Mohsin Ali, Alexey Dovzhenko, Rustem Zairov, Vladimir Mironov, Asiya Mustafina

Subject: Organic Chemistry, Chemistry And Materials Science Keywords: phosphine oxides; ligands; lanthanides; triketones; keto-enolic tautomerism

Online: 8 December 2023 (10:20:03 CET)

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Preprint ARTICLE | doi:10.20944/preprints202312.0572.v1

Effect of Calving Season and Related Climatic Factors on Productive Performance in Dairy Cows

Martin Stojnov, Toncho Penev, Dimo Dimov, Ivaylo Marinov

Subject: Animal Science, Veterinary Science And Zoology, Biology And Life Sciences Keywords: calving season; THI; lactation curve; fat content; protein content

Online: 8 December 2023 (10:17:59 CET)

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Preprint ARTICLE | doi:10.20944/preprints202312.0571.v1

Passive Surveillance as a Key Tool to African Swine Fever Eradications in Wild Boar: A Standardized Protocol to Find the Carcasses in Mediterranean Area.

Elisabetta Coradduzza, Federica Loi, Francesca Porcu, Daniela Mandas, Fabio Secci, Marco Efisio Pisanu, Cinzia Pasini, Carlo Zuddas, Marcella Cherchi, Daniele Denurra, Ennio Bandino, Antonio Pintore, Vittorio Guberti, Stefano Cappai

Subject: Animal Science, Veterinary Science And Zoology, Biology And Life Sciences Keywords: African swine fever; passive surveillance; carcasses; eradication; mobile app; freedom from animal disease; wild boar

Online: 8 December 2023 (10:16:19 CET)

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African Swine Fever (ASF) is one of the most important and serious contagious haemorrhagic viral disease of domestic pigs and wild boar, associated to high mortality rates and great sanitary and socioeconomic impact on international trade in animal and swine products. The early detection of the disease is often hampered by an inadequate surveillance. Among the surveillance strategies, passive surveillance of wild boar was considered the most effective for controlling African swine fever virus (ASFV). Otherwise, the design of a sufficiently sensitive ASF surveillance system re-quires a solid understanding of the epidemiology related to the local eco-social context, especially in absence of virus detection. Even if the number of carcasses needed to demonstrate the ASF eradication has been established, the scientific context is poor of details on protocols applied to active search the wild boar carcasses. The aim of the study was to describe the strategy applied for passive surveillance implemented in Sardinia, providing detailed information on the protocol applied in the field in term of number of people, dogs, time and space used to active search car-casses in the Mediterranean area. Using a specific tool developed to record, trace, and share on field data (GAIA Observer App), a total of 33 activities for active search the wild boar carcasses were organized during 2021-2023. Most of these activities were planned to find carcasses previously reported by hunters. A total of 24 carcasses were found, only 2 carcasses were not previously reported. The final protocol applied involved 4 people, with an average speed of 1.5 km/hour. When the carcass was reported, about 2 km of distance should be covered in about 1.5 hours to find the carcasses, and even less time was spent when the dog (not trained) was present. In conclusion, it can be stated that for searching for carcasses it is first mandatory a good collaboration with hunters or other forest visitors to report the carcasses, and involve small groups of expert people to active search the carcasses, possible with the use of hunting dogs with no special training.

Preprint ARTICLE | doi:10.20944/preprints202312.0575.v1

Effects of Silicon Content on Oxidation at 1000°C of Aisi 1045, Aisi 5160 and Aisi 9254 Steels.

Guilherme Maranhão Costa, Lioudmila Aleksandrovna Matlakhova, Sergio Neves Monteiro

Subject: Surfaces, Coatings And Films, Chemistry And Materials Science Keywords: high-temperature; silicon; oxidation

Online: 8 December 2023 (10:14:01 CET)

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Preprint ARTICLE | doi:10.20944/preprints202312.0570.v1

Transforaminal Endoscopic Lumbar Lateral Recess Decompression for Octogenarian Patients

Yong Ahn, Jun Hyeok Jung

Subject: Orthopedics And Sports Medicine, Medicine And Pharmacology Keywords: endoscopic; lateral recess; lumbar stenosis; octogenarians; radiculopathy; transforaminal

Online: 8 December 2023 (10:12:11 CET)

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Preprint ARTICLE | doi:10.20944/preprints202312.0583.v1

Drainless Technology for Processing High-Moisture Iron-Containing Sludge and Dust

Ibraev I.K., Ibraeva O.T.

Subject: Metallurgy And Metallurgical Engineering, Engineering Keywords: sludge; dust; processing; dehydration; agglomeration; recycling

Online: 8 December 2023 (10:11:37 CET)

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Annotation. PURPOSE. Development of a drainless energy-saving technology for the processing of high-moisture iron-containing sludge from metallurgical production. RESEARCH METHOD. The regularities of the combined process of chemical dehydration of high-moisture iron-containing sludge by powdered waste of lime and dolomite, hardening and agglomeration by pressing in a single technological cycle on the developed experimental plant are studied. In the course of laboratory studies, the temperature of the mass, the rate of dehydration, the chemical composition of the mixtures, the appearance of the resulting briquettes, the weight loss during agglomeration, the humidity of the mixtures, and the mechanical strength of the briquettes were carried out. RESULTS. New patterns have been established that have made it possible to develop a non-firing method for producing iron-containing material and self-healing briquettes. The essence of the method, which is one of the main provisions of scientific novelty, is to combine the processes of dehydration, self-hardening of the mixture with the process of shaping by applying external pressure to the hardening mixture in molds to obtain agglomerated material in the form of briquettes in a single technological cycle. The proposed technology does not require drying and firing, and a set of strength properties occurs as the material is cooled in air during the day. A new energy-efficient and drainless method for the production of iron-containing briquettes has been developed, which combines the processes of chemical dehydration and agglomeration in one technological cycle. CONCLUSION. The proposed project and technology will allow organizing production for the processing of high-moisture iron-containing sludge and obtaining a complex iron-containing material as a secondary metal-containing raw material for metallurgical plants for the production of steel and rolled metal. and dolomite dust of dry gas cleaning) as dehydrating and binding materials, as well as screening of coke and coal as a reducing agent. The proposed technology also solves the problems of environmental pollution and land acquisition for storage of production waste.

Preprint CASE REPORT | doi:10.20944/preprints202307.0642.v2

A rare case of complete-immunotherapy-responsive metastatic NSCLC with long lasting PFS: a case report and a literature review

Claudia De Intinis, Paolo Izzo, Massimo Codacci-Pisanelli, Luciano Izzo, Daniela Messineo, Simone Sibio, Monica Champagnol, Silvia Lai, Marcello Molle, Sara Izzo

Subject: Oncology And Oncogenics, Medicine And Pharmacology Keywords: NSCLC; metastasis; immunotherapy; complete response; case report; literature review

Online: 8 December 2023 (10:10:13 CET)

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Preprint ARTICLE | doi:10.20944/preprints202312.0589.v1

Exploring PTX3 as a Diagnostic and Prognostic Marker in Fetal Inflammatory Response Syndrome in Newborns: A Prospective Study

Bahar Öztelcan Gündüz, Ener Cağrı Dinleyici, Neslihan Ayşe Tekin, Ömer Çolak, Arif Mehmet Akşit

Subject: Pediatrics, Perinatology And Child Health, Medicine And Pharmacology Keywords: PTX3; NEWBORN BABY; FETAL İNFLAMMATORY SYNDROME; SEPSİS; RDS

Online: 8 December 2023 (10:09:23 CET)

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Preprint ARTICLE | doi:10.20944/preprints202312.0601.v1

Secure Proxy Re-Encryption Protocol for FANETs Resistant to Chosen Ciphertext Attacks

Hyun-A Park

Subject: Security Systems, Computer Science And Mathematics Keywords: Proxy Re-Encryption; FANET (Flying Ad-Hoc Network); off-road accident

Online: 8 December 2023 (10:07:28 CET)

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Preprint ARTICLE | doi:10.20944/preprints202312.0573.v1

The Archimedean Origin of Modern Positional Number Systems

Vincenzo Manca

Subject: Mathematics, Computer Science And Mathematics Keywords: Number Representation Systems; Zeroless positional systems; Arithmetic Algorithms; Ordinals; Recursive enumerability

Online: 8 December 2023 (10:06:12 CET)

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Preprint REVIEW | doi:10.20944/preprints202312.0598.v1

The NLRP3 Inflammasome as a Pathogenic Player Showing Therapeutic Potential in Rheumatoid Arthritis and Its Comorbidities: A Narrative Review

Po-Ku Chen, Kuo-Tung Tang, Der-Yuan Chen

Subject: Medicine And Pharmacology, Medicine And Pharmacology Keywords: NLRP3 inflammasome; comorbidities; pathogenic player; therapeutic potential; rheumatoid arthritis

Online: 8 December 2023 (10:01:25 CET)

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Preprint ARTICLE | doi:10.20944/preprints202312.0594.v1

Relapses and Serious Infections In Patients with Neuromyelitis Optica Spectrum Disorder Treated with Rituximab: A Swedish Cohort Study

Olof Carlsson, Dagur Ingi Jonsson, Lou Brundin, Ellen Iacobaeus

Subject: Neuroscience And Neurology, Medicine And Pharmacology Keywords: neuromyelitis optica disorder; anti-aquaporin-4; anti-myelin oligodendrocyte glycoprotein; rituximab; serious infection

Online: 8 December 2023 (09:59:09 CET)

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Preprint REVIEW | doi:10.20944/preprints202312.0579.v1

Driving Population Health through Accountable Care Organizations, Saudi Arabia

Ghanim. Hamid Al-Khattabi

Subject: Epidemiology And Infectious Diseases, Medicine And Pharmacology Keywords: Accountable Care Organizations; Public Health; Population Health Management; Transform Healthcare; National Transformation Program; Health Agencies

Online: 8 December 2023 (09:54:43 CET)

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Preprint CASE REPORT | doi:10.20944/preprints202312.0597.v1

Comparative Study of Organic Fertilizers on Growth, Development and Economics of Brinjal (Solanum melongena var. Azad B-3) with Reference to Temperature.

vidyasagar yashvardhan, Rambatuk Singh, Devendra pratap singh, Tribhuwan singh

Subject: Agricultural Science And Agronomy, Biology And Life Sciences Keywords: organic fertilizers; vermicompost; poultry manure; mustard cake; bonemeal, neemcake

Online: 8 December 2023 (09:25:59 CET)

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Preprint ARTICLE | doi:10.20944/preprints202312.0596.v1

Multi-Objective Optimization by Means of Pairs of Functions

Gianni Bosi, Daris Roberto, Magalì Zuanon

Subject: Mathematics, Computer Science And Mathematics Keywords: Pareto optimal elemen; Bi-multi-objective optimization; Interval order; Ambiguity; Markowitz portfolio selection

Online: 8 December 2023 (09:17:23 CET)

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Preprint ARTICLE | doi:10.20944/preprints202312.0560.v1

Greater Energy Independence with Sustainable Steel Production

By Sandra Kiessling, Hamidreza Gohari Darabkhani, Abdel-Hamid Ali Soliman

Subject: Energy And Fuel Technology, Engineering Keywords: Energy Independence; Sustainable Steel; Net-Zero

Online: 8 December 2023 (08:36:07 CET)

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Preprint REVIEW | doi:10.20944/preprints202312.0565.v1

What Health Concerns Could Micro and Nanoplastics Pose for Infants? A Review

Antonio Ragusa, Denise Rinaldo

Subject: Pollution, Environmental And Earth Sciences Keywords: Plastic; microplastics; nanoplastics; newborns; breastfeeding; plastic products manufacturers; human behaviors

Online: 8 December 2023 (08:32:49 CET)

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Preprint ARTICLE | doi:10.20944/preprints202312.0564.v1

Bridging Digital Competence and Sustainability: Unveiling the Synergistic Potential of Design and Maker Education

Noble Po-kan Lo

Subject: Education, Social Sciences Keywords: maker education; green digital skills; problem-solving; innovation; creativity; engagement; sustainable education

Online: 8 December 2023 (08:31:01 CET)

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Preprint HYPOTHESIS | doi:10.20944/preprints202301.0155.v3

Benveniste’s Experiments and the So-Called “Water Memory” Phenomenon: an Example of Serendipity?

Francis BEAUVAIS

Subject: Other, Medicine And Pharmacology Keywords: Water memory; High dilutions; Scientific controversy; Serendipity; Experimenter effect

Online: 8 December 2023 (08:25:02 CET)

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Preprint ARTICLE | doi:10.20944/preprints202312.0574.v1

Computational Screening and Experimental Validation of Inhibitor Targeting the Complex Formation of Grb14 and Insulin Receptor

Yosuke Ochi, Takanori Matsui, Keitaro Inoue, Kohei Monobe, Hiroshi Sakamoto, Shunsuke Aoki, Junichi Taira

Subject: Biochemistry And Molecular Biology, Biology And Life Sciences Keywords: DOCK program; GOLD program; Grb14; insulin receptor (IR); structure-based drug screening (SBDS)

Online: 8 December 2023 (08:24:15 CET)

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Preprint ARTICLE | doi:10.20944/preprints202312.0543.v1

Fekete-Szego and Zalcman Functional Estimates for Subclasses of Alpha-Convex Functions Related to Trigonometric Functions

Krishnan Marimuthu, Uma Jayaraman, TEODOR BULBOACA

Subject: Analysis, Computer Science And Mathematics Keywords: Analytic functions; subordination; Carathé; odory functions; sine function; cosine function; alpha-convex functions; starlike and convex functions; coefficient bounds; Fekete-Szeg˝o functional; Zalcman functional

Online: 8 December 2023 (08:04:52 CET)

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Preprint ARTICLE | doi:10.20944/preprints202312.0544.v1

A Convergence Criterion for a Class of Stationary Inclusions in Hilbert Spaces

Mircea Sofonea, Domingo A. Tarzia

Subject: Applied Mathematics, Computer Science And Mathematics Keywords: stationary inclusion; projection operator; convergence criterion; convergence results; penalty method, frictional contact problem; elastic constitutive law

Online: 8 December 2023 (08:02:46 CET)

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Preprint ARTICLE | doi:10.20944/preprints202312.0547.v1

Comparison Between Different Seasons of the Year in Research for Rotavirus in a State of Brazil

Graziela Picciola Bordoni, Lucas Candido Gonçalves Barbosa, Fernando Santos Lima, Monica De Oliveira Santos, José Daniel Gonçalves Vieira, Paulo Sergio Scalize, Lilian Carla Carneiro

Subject: Water Science And Technology, Environmental And Earth Sciences Keywords: Rotavirus; Water contamination; Dry period; Rainy period

Online: 8 December 2023 (08:01:08 CET)

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Abstract: Rotavirus (RV) it’s the agent of one of the main causes of severe viral gastroenteritis in the pediatric population, being responsible for a significant portion of deaths related to diarrhea among children under five years. RV are identified as a potential reference pathogen and it is known that the persistence and infectivity of the viral particles can be related to environmental factors. The aim of the study was to identify and correlate the presence of Rotavirus in collective and individual water sources (deep tubular wells, shallow tubular wells, shallow dug wells, springs, surface water, rainwater stored in cisterns and water trucks that were collected from surface water) of rural communities in the state of Goiás, with the seasons in which the collections were made (rainy and dry season). For this, 86 water samples in the dry period and 160 samples in the rainy period were collected. Concentration of water samples, extraction of viral genetic material, cDNA synthesis and molecular tests (qPCR) were performed. When analyzing the presence of RV in the samples in relation to the period studied, RV was found to be more prevalent in the dry season (54.7%) than in the rainy season (20%), showing a strong statistical association with the dry season (p-value < 0.001). The proportion of positive samples in the dry period, considering the type of source, resulted in higher in Shallow dug wells (p-value <0.001), higher in surface waters (p = 0.001) and higher in spring water (p-value = 0.02). The presence of pathogenic microorganisms in water is a public risk problem, enabling the emergence of outbreaks, endemics and epidemics. In the present research, there was an association among the presence of Rotavirus and the dry period of the year, when compared to the rainy period. Describing or identifying the seasonal behavior of pathogens is important for prevention and attention to water treatment and help in the monitoring of the virus in the water sources.

Preprint ARTICLE | doi:10.20944/preprints202312.0550.v1

Human Serum Enriched After Absorption of Fish Cartilage Hydrolysate Enhances the Healing of Primary Human Dermal Fibroblasts Through the Expression of Proteins with Anti-Inflammatory and Immunomodulatory Properties

Julie Le Faouder, Aurelie Gueho, Regis Lavigne, Fabien Wauquier, Line Boutin-Wittrant, Elodie Bouvret, Emmanuelle Com, Yohann Wittrant, Charles Pineau

Subject: Biology And Biotechnology, Biology And Life Sciences Keywords: skin health; nutraceuticals; marine hydrolyzed collagen; marine collagen peptides; chondroitin sulfate; glycosaminoglycans; proteomics; wound healing; primary cells; human dermal fibroblasts; clinical; ex vivo

Online: 8 December 2023 (07:53:19 CET)

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Preprint REVIEW | doi:10.20944/preprints202312.0569.v1

Alpha-Synuclein Aggregation and Spread: Implications for the Pathology and Progression of Neurodegenerative Diseases

Alin Bose Johnson, Niharika Modi, Krithik N. Kamath, Raman Rajeshkumar, Vasanth Raj Palanimuthu

Subject: Neuroscience And Neurology, Biology And Life Sciences Keywords: neurodegenerative diseases; Lewy bodies; neurodegenerative; A53T mutation

Online: 8 December 2023 (07:47:36 CET)

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Preprint REVIEW | doi:10.20944/preprints202312.0514.v1

Macrophage polarization in infectious diseases: PAMP, viru-lence factors, immune signaling and receptors

Cláudio Daniel Cerdeira, Maísa R.P.L. Brigagão

Subject: Immunology And Allergy, Medicine And Pharmacology Keywords: Macrophage; polarization; receptor; bacteria; virus; fungi; parasites

Online: 8 December 2023 (07:39:15 CET)

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Preprint ARTICLE | doi:10.20944/preprints202312.0563.v1

Topside Ionospheric Structures Determined by Automatically Detected DEMETER Ion Perturbations

Mei Li, Hongzhu Yan, Yongxian Zhang

Subject: Space Science, Physical Sciences Keywords: Ionospheric Structures; Ion Perturbations; Automatic detection method

Online: 8 December 2023 (07:37:49 CET)

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Preprint COMMUNICATION | doi:10.20944/preprints202312.0566.v1

Bottlebrush Elastomers with Crystallizable Side Chains: Monolayer-Like Structure of Backbones Segregated in Intercrystalline Regions Title

Evgeniia A. Nikitina, Erfan Dashtimoghadam, Sergei S. Sheiko, Dimitri A. Ivanov

Subject: Polymers And Plastics, Chemistry And Materials Science Keywords: bottlebrush elastomers; X-ray scattering; polymer crystallization

Online: 8 December 2023 (07:37:17 CET)

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Preprint ARTICLE | doi:10.20944/preprints202312.0568.v1

Microstructure Study on Very-High-Cycle Fatigue of an Addi-tively Manufactured Aluminium Alloy via Advanced Charac-terization Methods

Lu Liu, Shengnan Wang, Gang Li, Yifan Ma

Subject: Other, Engineering Keywords: mechanical behavior; aluminium alloy; additive manufacturing; very-high-cycle fatigue (VHCF); crack initiation; microstructure; focused ion beam (FIB); optical microscopy (OM); scanning electron microscopy (SEM); transmission electron microscopy (TEM)

Online: 8 December 2023 (07:36:32 CET)

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Preprint ARTICLE | doi:10.20944/preprints202312.0567.v1

Discrete-Time Adaptive Control for Uncertain Scalar Multiagent Systems with Coupled Dynamics: A Lyapunov-Based Approach

Islam A. Aly, Kadriye Merve Dogan

Subject: Control And Systems Engineering, Engineering Keywords: multiagent system; discerete-time control; adaptive control; coupled dynamics

Online: 8 December 2023 (07:31:43 CET)

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Preprint ARTICLE | doi:10.20944/preprints202312.0562.v1

A Comparative Study of Sports Consumption Psychology and Behavior between Chinese and British University Students

Puyan Chi, Xueying Zhu, Yun Bai, Baoping Wang, Aiping Chi, Tao Xiao

Subject: Psychology, Social Sciences Keywords: Exercise Habits; Sports Consumption; Sports Behavior; College Students; China; Britain

Online: 8 December 2023 (05:59:25 CET)

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Preprint DATA DESCRIPTOR | doi:10.20944/preprints202312.0561.v1

The VIS-Spectrometric Data of Scots Pine Individual Seed Reveal Forecasting Potential for Container-Grown Germination and Seedling’s Dickson Quality Index

Tatyana P. Novikova, Evgeniy P. Petrishchev, Arthur I. Novikov

Subject: Forestry, Biology And Life Sciences Keywords: Pinus sylvestris L.; Scots pine; seed spectrometric feature; individual seed; container-growm germination; RGB color space; L*a*b* color space; seed size; individual seed mass; Dickson quality index (DQI); forest landscape restoration (FLR)

Online: 8 December 2023 (05:47:28 CET)

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Preprint ARTICLE | doi:10.20944/preprints202312.0533.v1

ERK1 Is a Regulatory Kinase Coordinating ERK2 Function in Colon Adenocarcinoma

Alessia Parascandolo, Giulio Benincasa, Francesco Corcione, Mikko O. Laukkanen

Subject: Life Sciences, Biology And Life Sciences Keywords: Colon tumorigenesis; ERK1/2; SOD3; migration, invasion; proliferation

Online: 8 December 2023 (04:56:53 CET)

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Preprint ARTICLE | doi:10.20944/preprints202312.0557.v1

Decoupling and Cloaking of Rectangular and Circular Patch Antennas and Interleaved Antenna Arrays with Coated Metasurfaces at C-Band Frequencies

Shefali Pawar, Doojin Lee, Harry Skinner, Seong-Youp Suh, Alexander Yakovlev

Subject: Electrical And Electronic Engineering, Engineering Keywords: cloaking; coated metasurfaces; microstrip patch antennas; mutual interference; reduction of mutual coupling

Online: 8 December 2023 (04:46:53 CET)

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Preprint ARTICLE | doi:10.20944/preprints202312.0556.v1

Cross-layer Methods for Ad Hoc Networks Review and Classification

Valeriy Ivanov, Maxim Tereshonok

Subject: Telecommunications, Engineering Keywords: cross-layer methods; ad hoc networks; OSI; optimisation; classification; review

Online: 8 December 2023 (04:43:08 CET)

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Preprint ARTICLE | doi:10.20944/preprints202312.0559.v1

Organizational Behavior as a key factor to the success of Sustainable Policies and Actions: A research in the Greek Healthcare Sector

Anastasios Sepetis, Ioannis Parlavantzas, Aspasia Goula, Georgios Pierrakos, Fotios Rizos

Subject: Public, Environmental And Occupational Health, Public Health And Healthcare Keywords: Organizational Behavior; Sustainable development; Climate change; Environment; Greece

Online: 8 December 2023 (04:39:42 CET)

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Preprint ARTICLE | doi:10.20944/preprints202312.0558.v1

Experimental Evaluation of a Takagi-Sugeno Fuzzy Controller for an EV3 Ballbot System

Rodolfo Enemegio, Francisco Jurado, Jonathan Villanueva-Tavira

Subject: Control And Systems Engineering, Engineering Keywords: ballbot; linear matrix inequalities; parallel distributed compensation; Takagi-Sugeno fuzzy control; Takagi-Sugeno fuzzy model; telecontrol; telemetry; underactuated systems

Online: 8 December 2023 (04:37:49 CET)

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Preprint COMMUNICATION | doi:10.20944/preprints202312.0554.v1

A Study on Automated Problem Troubleshooting in Cloud Environments with Rule Induction and Verification

Arnak Poghosyan, Ashot Harutyunyan, Edgar Davtyan, Karen Petrosyan, Nelson Baloian

Subject: Artificial Intelligence And Machine Learning, Computer Science And Mathematics Keywords: automated troubleshooting; real-time product activity detection; problem root cause analysis; machine learning; explainable AI; proactive SaaS support

Online: 8 December 2023 (04:34:50 CET)

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Preprint ARTICLE | doi:10.20944/preprints202312.0488.v1

Adaptive Responses of Biofortified Common Bean Lines to Acidic Soil and High Temperature in the Amazon Region of Colombia

Juan Carlos Suárez, Amara Tatiana Contreras, Milan O. Urban, Miguel Angel Grajales, Stephen E. Beebe, Idupulapati M. Rao

Subject: Agricultural Science And Agronomy, Biology And Life Sciences Keywords: energy use; leaf cooling; phenology; photosynthesis; photosynthate partitioning

Online: 8 December 2023 (03:43:07 CET)

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The development of biofortified and stress tolerant common bean lines contribute to counteract micronutrient malnutrition in the current condition of climate variability. Our objective was to evaluate the adaptive responses of biofortified common bean (Phaseolus vulgaris L.) lines under acidic soils and high temperature stress conditions in the Amazon region of Colombia. Adaptive responses were evaluated based on phenological, physiological and agronomic differences under combined stress conditions. A total of 247 common bean lines from the Mesoamerican gene pool were evaluated under field conditions at Florencia, Caquetá, Colombia. The common bean lines evaluated included 146 from F4 families with high iron (Fe) content and 99 common bean lines from F5 families that were obtained from simple crosses, double crosses and backcrosses among different bean lines. Lines with tolerance to combined stress conditions of acidic soil and high temperature were found with grain yields greater than 1,400 kg ha-1 from the F5 (lines: 859, 805, 865, 657) and F4 (lines: 2853, 2796) families. This improved agronomic response is likely due to the greater partitioning of photosynthates from canopy biomass (CB) toward pod formation (pod partitioning index, PPI) and grain filling (pod harvest index, PHI; harvest index, HI), which translated into higher grain yields (GY). GY was correlated with CB (r = 0.36), PPI (r = 0.6), PHI (r = 0.68), and HI (r = 0.8, P<0.001). The physiological responses that contributed toward superior agronomic performance of biofortified common bean lines include greater allocation of energy to the photosynthetic machinery (ΦII) and its dissipation in the form of heat (ΦNPQ) as the leaf temperature differential (LTD) increased under combined stress conditions. Six biofortified common bean lines (F5 lines: 859, 805, 865, 657; F4 lines: 2853, 2796) were identified with multiple stress resistance traits and these lines can serve as parents for further genetic improvement of common bean for multiple stress tolerance in the Amazon region of Colombia.

Preprint REVIEW | doi:10.20944/preprints202312.0536.v1

DNA Barcoding as a Plant Identification Method

Stavroula Letsiou, Panagiotis Madesis, Efstathios Vasdekis, Cinzia Montemurro, Maria E. Grigoriou, George Skavdis, Vasillios Moussis, Antonios E. Koutelidakis, Andreas G. Tzakos

Subject: Life Sciences, Biology And Life Sciences Keywords: DNA Barcoding; species identification; taxonomy; plants; molecular markers

Online: 8 December 2023 (03:34:41 CET)

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Preprint ARTICLE | doi:10.20944/preprints202312.0551.v1

An Improved Ambiguity-free Unfolded Co-prime Linear Array Design for DOA Estimation

Pan Gong, Xiaofei Zhang

Subject: Electrical And Electronic Engineering, Engineering Keywords: direction of arrival estimation, improved array arrangement design, improved unfolded coprime linear array, Cramer-Rao bound, multiple signal classification ;

Online: 8 December 2023 (03:31:10 CET)

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Preprint ARTICLE | doi:10.20944/preprints202312.0538.v1

NaCl Tolerance during Germination and Seedling Stages of Tomato (Solanum lycopersicum L.) Lines Native to Mexico

Ariadna Goreti López-Méndez, Juan Enrique Rodríguez-Pérez, José Oscar Mascorro-Gallardo, Jaime Sahagún-Castellanos, Ricardo Lobato-Ortiz

Subject: Horticulture, Biology And Life Sciences Keywords: salt tolerant genotypes; wild tomato; developmental stages; seed germination

Online: 8 December 2023 (03:12:47 CET)

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Preprint ARTICLE | doi:10.20944/preprints202312.0542.v1

Evolution and Structure of a Mesoscale Anticyclonic Eddy in the Northwestern Japan Sea and Its Exchange with Surrounding Waters: In Situ Observations and Lagrangian Analysis

Maxim Budyansky, Svetlana Ladychenko, Vyacheslav Lobanov, Sergey Prants, Aleksandr Alekseevich Udalov

Subject: Oceanography, Environmental And Earth Sciences Keywords: northwestern Japan Sea; mesoscale eddy; evolution and structure; Lagrangian analysis

Online: 8 December 2023 (03:02:17 CET)

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Preprint COMMUNICATION | doi:10.20944/preprints202312.0417.v2

Sequential Therapy with Ropeginterferon Alfa-2b and Anti-PD1 Antibody for Inhibiting Recurrence of Hepatitis B-related Hepatocellular Carcinoma: From Animal Modeling to Phase I Clinical Results

Albert Qin, Chang-Ru Wu, Ming-Chih Ho, Chan-Yen Tsai, Pei-Jer Chen

Subject: Medicine And Pharmacology, Medicine And Pharmacology Keywords: Hepatocellular carcinoma; HBV-related; anti-PD1 antibody; ropeginterferon alfa-2b; animal HBV model; clinical trial

Online: 8 December 2023 (02:53:09 CET)

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Preprint ARTICLE | doi:10.20944/preprints202312.0539.v1

Sulfuric Acid Digestion of Anatase Concentrate

Carolina Nogueira Silva, Liliani Pacheco Tavares Nazareth, Monica Elizetti Freitas, Ana Claudia Queiroz Ladeira

Subject: Metallurgy And Metallurgical Engineering, Engineering Keywords: Keywords: anatase, titanium, sulphation, phosphorus

Online: 8 December 2023 (01:20:44 CET)

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Preprint ARTICLE | doi:10.20944/preprints202312.0549.v1

Multi-Performance-Degradation System Reliability Analysis with Varying Failure Threshold Based on Copula

WeiZHeng Gan, JiaYin Tang

Subject: Safety, Risk, Reliability And Quality, Engineering Keywords: Linear Wiener process；Multi-Performance-Degradation；Competitive Failure；Copula Function; Variation of Failure Threshold.

Online: 8 December 2023 (01:18:36 CET)

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Preprint REVIEW | doi:10.20944/preprints202312.0546.v1

Cultivation of Vitamin C-Rich Vegetables for Space Radiation Mitigation

Alireza Mortazavi, Helia Yarbaksh, B.F. Bahaaddini Baigy Zarandi, Reza Yarbakhsh, Fatemeh Ghadimi-Moghaddam, SMJ Mortazavi, Masoud Haghani, Donya Firoozi, Lembit Sihver

Subject: Physical Sciences, Radiation And Radiography Keywords: radiation, C-vitamin; solar particle event; SPE; antioxidants; radiation mitigator

Online: 7 December 2023 (19:55:54 CET)

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Preprint REVIEW | doi:10.20944/preprints202312.0548.v1

Advances in Mass Spectrometry of Gangliosides Expressed in Brain Cancers

Maria Roxana Biricioiu, Mirela Sarbu, Raluca Ica, Željka Vukelić, Svjetlana Kalanj-Bognar, Alina D. Zamfir

Subject: Biology And Life Sciences, Biochemistry And Molecular Biology Keywords: brain cancers; gangliosides; mass spectrometry; biomarker discovery; screening; structural analysis

Online: 7 December 2023 (19:55:09 CET)

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Preprint ARTICLE | doi:10.20944/preprints202312.0502.v1

Investigation on the Performance of Battery Thermal Management Based Direct Refrigerant Cooling: Simulation, Validation of Results and Parametric Studies

Suparat Jamsawang, Saharat Chanthanumataporn, Kittiwoot Sutthivirode, Tongchana Thongtip

Subject: Engineering, Mechanical Engineering Keywords: BTMS; Refrigerant Cooling; Evaporation heat transfer; EVs

Online: 7 December 2023 (17:10:58 CET)

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Preprint ARTICLE | doi:10.20944/preprints202312.0499.v1

Mapping Soil Organic Carbon Stock and Uncertainties in an Alpine Valley (Northern Italy) Using Machine Learning Models

Sara Agaba, Chiara Ferre, Marco Musetti, Roberto Comolli

Subject: Environmental And Earth Sciences, Soil Science Keywords: SOC stock; DSM; machine learning models; uncertainty mapping

Online: 7 December 2023 (17:03:15 CET)

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In this study, we conducted a comprehensive analysis of the spatial distribution of soil organic carbon stock (SOC stock) and the associated uncertainties in two soil layers (0–10 cm and 0–30 cm; SOC stock 10 and SOC stock 30 respectively), in Valchiavenna, an alpine valley located in northern Italy . We employed the digital soil mapping (DSM) approach within different machine learning models, including multivariate adaptive regression splines (MARS), random forest (RF), support vector regression (SVR), and elastic net (ENET). Our dataset comprised soil data from 110 profiles, with SOC stock calculations for all sampling points based on bulk density (BD), whether measured or estimated, considering the presence of rock fragments. As environmental covariates for our research we utilized environmental variables, in particular geomorphometric parameters derived from a digital elevation model (with a 20 m pixel resolution), land cover data, and climat-ic maps. To evaluate the effectiveness of our models, we evaluated their capacity to predict SOC stock 10 and SOC stock 30 using the coefficient of determination (R2). The results for the SOC stock 10 were as follows: MARS 0.39, ENET 0.41, RF 0.69, and SVR 0.50. For the SOC stock 30, the corresponding R2 values were: MARS 0.45, ENET 0.48, RF 0.65, and SVR 0.62. Additionally, we calculated the Root Mean Square Error (RMSE) and Mean Absolute Error (MAE) for further assessment. To map the spatial distribution of SOC stock and address uncertainties in both soil layers, we chose the RF model, due to its better performance, as indicated by the highest R2 and the lowest RMSE and MAE. The resulting SOC stock maps using the RF model demonstrated an accuracy of RMSE = 1.35 kg.m-2 for the SOC stock 10 and RMSE= 3.36 kg.m-2 for the SOC stock 30. To further evaluate and illustrate the precision of our soil maps, we conducted an uncertainty assessment and mapping by analyzing the standard deviation (SD) from 50 iterations of the best-performing RF model. This analysis effectively highlighted the high accuracy achieved in our soil maps. The maps of uncertainty demonstrated that the RF model better predicts the SOC stock 10 compared to the SOC stock 30.

Preprint ARTICLE | doi:10.20944/preprints202312.0495.v1

Microbiological Collections in Brazil: Current Status and Perspectives

Chirlei Glienke, Desirrê Alexia Lourenço Petters-Vandresen, Aline da Silva Soares Souto, Manuela da Silva, Luciane Marinoni

Subject: Biology And Life Sciences, Biology And Biotechnology Keywords: culture collections; biological collections; biodiversity; conservation

Online: 7 December 2023 (16:59:06 CET)

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Preprint ARTICLE | doi:10.20944/preprints202312.0497.v1

Cellular Biophysical Markers for Rapid Evaluation of Immune Checkpoint Inhibitors in Radioimmunotherapy Against Glioblastomas

Bayode Ibironke, Kylie Machida, Arij Khan, Jayce Hughes, Melanie Schwengler, Allison Benoit, Erika Jank, Anne Hubbard, Yohan Walter, Andrew Ekpenyong

Subject: Medicine And Pharmacology, Oncology And Oncogenics Keywords: pembrolizumab; immunotherapy; temozolomide; durvalumab; brain tumor; cell migration; metastasis; glioblastoma; PD-1; PD-L1

Online: 7 December 2023 (16:57:26 CET)

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Preprint ARTICLE | doi:10.20944/preprints202312.0493.v1

Investigating Novel IspE Inhibitor of MEP Pathway in Mycobacterium

Seoung-ryoung Choi, Prabagaran Narayanasamy

Subject: Chemistry And Materials Science, Medicinal Chemistry Keywords: pathogens; IspE inhibitor; carboline, synthesis; minimum inhibitory concentration

Online: 7 December 2023 (16:54:59 CET)

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Preprint ARTICLE | doi:10.20944/preprints202312.0494.v1

Redox-Active Cerium Fluoride Nanoparticles Mitigate of Double-Stranded DNA Breakage and Modulate Gene Expression Due to Radiation Exposure In Vitro

Nikita N. Chukavin, Kristina O. Fillipova, Artem M. Ermakov, Ekaterina E. Karmanova, Nelli R. Popova, Viktoriia A. Anikina, Olga S. Ivanova, Vladimir K. Ivanov, Anton L. Popov

Subject: Biology And Life Sciences, Life Sciences Keywords: cerium fluoride nanoparticles; DNA reparation; double-strand brakes; X-ray radiation

Online: 7 December 2023 (16:53:40 CET)

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Preprint ARTICLE | doi:10.20944/preprints202312.0491.v1

Multilayer Perceptron-based Error Compensation for Automatic On-the-Fly Camera Orientation Estimation using a Single Vanishing Point from Road Lane

Xingyou Li, Hyoungrae Kim, Vijay Kakani, Hakil Kim

Subject: Engineering, Electrical And Electronic Engineering Keywords: Autonomous vehicles; camera orientation estimation; vanishing point; camera extrinsic parameters

Online: 7 December 2023 (16:49:02 CET)

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Preprint ARTICLE | doi:10.20944/preprints202312.0485.v1

Effects of Plant Polysaccharides Combined with Boric Acid on Digestive Function, Immune Function, and Harmful Gas and Heavy Metal Contents in Faeces of Finishing Pigs

Juan Deng, Feng Zhang, Haoran Fan, Yuxuan Zheng, Chufang Zhao, Man Ren, Erhui Jin, Youfang Gu

Subject: Biology And Life Sciences, Animal Science, Veterinary Science And Zoology Keywords: Plant polysaccharides; Boric acid; finishing pigs; Digestive enzymes; Immune; Antioxidant; Harmful gases

Online: 7 December 2023 (16:44:22 CET)

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Preprint CASE REPORT | doi:10.20944/preprints202312.0501.v1

Switching from VA-ECMO to a Percutaneous Right Ventricular Assist Device as a Bridge to Recovery in a Case of Right Ventricular Myocardial Infarction

Benjamin Assouline, Damiano Mugnai, Andres Hagerman, Lydia Wuarin, Léonore Schopfer, Karim Bendjelid, Raphaël Giraud

Subject: Medicine And Pharmacology, Cardiac And Cardiovascular Systems Keywords: VA-ECMO; Short-term mechanical assist device; Right ventricular assist device; ProtekDuo; Cardiogenic shock; Right ventricular myocardial infarction.

Online: 7 December 2023 (16:41:21 CET)

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Preprint REVIEW | doi:10.20944/preprints202312.0489.v1

Review of the Brain Behaviour after Injury and Disease for Its Application in an Agent Based Model (ABM)

Luis Irastorza Varela, José María Benítez Baena, Francisco Montans, Luis Saucedo-Mora

Subject: Engineering, Bioengineering Keywords: Connectome; Brain Injury; Neurodegenerative Diseases; Parkinson; Alzheimer; Dislexia

Online: 7 December 2023 (16:39:47 CET)

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Preprint ARTICLE | doi:10.20944/preprints202312.0486.v1

Mucocutaneous Manifestations Reported by Inflammatory Bowel Disease Patients in University Hospital

Ieva Renata Jonaitytė, Vita Karpavičiūtė, Gediminas Kiudelis, Juozas Kupčinskas, Laimas Jonaitis

Subject: Medicine And Pharmacology, Dermatology Keywords: ulcerative colitis; Crohn’s disease; extraintestinal manifestation; skin lesions; mucocutaneous lesions

Online: 7 December 2023 (16:37:53 CET)

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Preprint ARTICLE | doi:10.20944/preprints202312.0484.v1

Synthesized Ligands of Amino Phenyl TIPS-pentacene and Tetraphenylporphyrin for Singlet Fission

Shaimaa Abdalbaqi

Subject: Physical Sciences, Applied Physics Keywords: semiconductor nanocrystals, PbS nanocrystals, coupled organic-inorganic nanostructures,
ligands

Online: 7 December 2023 (16:31:32 CET)

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Preprint REVIEW | doi:10.20944/preprints202312.0545.v1

Therapeutic Strategies in Children with Epilepsy-from the Point of View of QOL-Related Factors-

Hideaki Kanemura

Subject: Medicine And Pharmacology, Pediatrics, Perinatology And Child Health Keywords: frontal; prefrontal; behavior; stigma; seizure severity; interictal epileptiform discharge (IED); quality of life (QOL)

Online: 7 December 2023 (15:57:26 CET)

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Children with epilepsy are affected by several factors, including clinical and social variables, which can lead to reductions in quality of life (QOL). Among these variables, factors relating to seizure severity such as frequent seizures and status epilepticus (SE) have been identified as important predictors of QOL. In addition, frequency of interictal epileptiform discharges (IEDs) on the electroencephalogram (EEG) may also lead to cognitive declines and behavioral disturbances. Moreover, frequent seizures and/or IEDs may play a role in emotional mediators such as stigma and fatigue in childhood epilepsy. Seizure severity and/or IEDs are thus important QOL-related factors in childhood epilepsy. Frontal lobe dysfunctions such as cognitive decline and behavioral disturbances can result in reduced QOL for both the child and their family. Frontal and prefrontal lobe growth disturbances can be present during active-phase epilepsy in some children with neuropsychological impairments. Recovery from prefrontal lobe growth disturbance may depend on the active seizure period. Disturbance of prefrontal lobe growth can recover more rapidly in children with a shorter active seizure period. In contrast, recovery may be delayed in children with a longer active seizure period. Accordingly, severe seizures can lead to neuropsychological impairments in association with prefrontal lobe growth disturbance in children with epilepsy. Moreover, frequent seizures can lead to having seizure-associated headache, perception of self-stigma and parental stigma, and fatigue. In addition, IEDs on EEG, representing persistent pathological neuronal discharges, may be associated with several pathological aspects. Frontal IEDs can be a risk factor for recurrent seizures, cognitive decline, and behavioral disturbances and may also play a role as an emotional mediator similar to stigma. In addition, behavioral disturbances may result in the presence of secondary bilateral synchrony (SBS) on EEG. Behavioral disturbances can be improved in association with reduction of IEDs in children with frontal IED and SBS. Seizure severity and IEDs on EEG may thus be associated with neuropsychological impairments, leading to QOL reduction. Therapeutic management may be desirable to remit seizures and EEG abnormalities such as frontal IED and SBS as soon as possible to improve QOL in children with epilepsy.

Preprint REVIEW | doi:10.20944/preprints202312.0433.v1

The Varied Impacts of Vascular Endothelial Growth Factor-a (VEGF-a) on Vasculature in Ovarian Hyper Stimulation Syndrome (OHSS) and Obesity

Fatemeh Rahimianfar, Mahtab Rahimianfar, Sahar Eshghjoo

Subject: Medicine And Pharmacology, Obstetrics And Gynaecology Keywords: obesity; VEGF-A; vascular permeability; ovarian hyper stimulation syndrome; adipose tissue; angiogenesis; adipocytes; endothelial cell; IVF; infertility

Online: 7 December 2023 (14:58:43 CET)

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Preprint ARTICLE | doi:10.20944/preprints202312.0432.v1

Temperature Programmed Photoelectron Emission (TPPE) to Analyze Electron Transfer on Metallic Copper and Its Relation to the Essential Role of the Surface Hydroxyl Radical

Yoshihiro Momose

Subject: Chemistry And Materials Science, Surfaces, Coatings And Films Keywords: TPPE; Copper surface; Electron transfer; Photoelectron emission; Abrasion; Ultrasonic cleaning; Temperature scan; Wavelength scan; Alcohols and water; Acid and base interaction; Activation energy; Acc

Online: 7 December 2023 (14:57:45 CET)

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Surface processes such as coatings, corrosion, photocatalysis, and tribology are greatly diversified by acid-base interaction at the surface overlayer. This study focuses on the action of metallic copper surface as an electron donor/acceptor related to inactivation of viruses; it was found that regarding Cu2O or Cu materials electrostatic interaction plays a major role in virus inactivation. We applied TPPE method to clarify the mechanism of electron transfer (ET) occurring at light irradiated copper surfaces. The TPPE characteristics was strongly influenced by the environments, which correspond to the temperature and environment dependence of the total count of emitted electrons in the incident light wavelength scan (PE total count, NT), the photothreshold, and further the activation energy (E) analyzed from Arrhenius plot of NT values obtained in the temperature-increase and subsequent temperature-decrease processes. In this study we reexamined the dependence of the TPPE data from two types of Cu metal surfaces: Sample A, which was mechanically abraded in alcohols, water, and air, and Sample C, which was only ultrasonically cleaned in these liquids. The NT for both Samples slowly increased with increasing temperature, reached a maximum (NTmax) at 250C (maximum temperature, Tmax), and after that decreased. For Sample A the NTmax value decreased in the order H2O > CH3OH > C2H5OH > (CH3)2CHOH > C3H7OH, although the last alcohol gave Tmax = 100C, while with Sample C the NTmax value decreased in the order: C3H7OH > (CH3)2CHOH > C2H5OH > CH3OH > H2O. Interestingly, both orders of the liquids were completely opposite: this means that Cu surface can possess two-way character. The NT intensity was found to be strongly associated with the change of the hydroxyl group (Cu-OH) to the oxide oxygen (O2) in the O1s spectra in the XPS measurement. The difference between the above orders was explained by the acid-base interaction mode of the Cu-OH group with the adsorbed molecule on the surfaces. The H2O adsorbed on Sample A produces the electric dipole Cu-OH+---:OH2 (--- hydrogen bond), while the C3H7OH and (CH3)2CHOH adsorbed on Sample C produce ROH+---:O(H)-Cu (R = alkyl groups). Gutmann’s acceptor number (AN) representing the basicity of the liquid molecules was found to be related to the TPPE characteristics: (CH3)2CHOH (33.5), C2H5OH (37.1), CH3OH (41.3), H2O (54.8) (the AN of C3H7OH could not be confirmed). With Sample A the values of NTmaxa and EaUp1 both increased with increasing AN (Up1 means the 1st temperature-increase process). On the other hand, with Sample C the values of NTmaxc and EcUp1 both decreased with increasing AN. These findings suggest that Sample A acts as an acid, while Sample C functions as a base. However, in the case of both types of Samples A and C the NTmax values were found to increase with increasing EUp1. It was explained that the EUp1 values depending on the liquids originate from the difference in the energy level of the hydroxyl group radical at the surface denoted. This is able to attract electrons in the neighborhood of the Fermi level of the base metal by tunnelling. After that due to Auger emission electrons are released, leading to the ET in the overlayer. These electrons are considered to have a strong ability of reducibility.

Preprint COMMUNICATION | doi:10.20944/preprints202312.0513.v1

The MAPT Isoform 0N3R Is Essential for Human Brain Development and Intolerant to Haploinsufficiency – Loss of Function as Disease Mechanism for TAU Associated Disease

Hans Zempel

Subject: Biology And Life Sciences, Neuroscience And Neurology Keywords: TAU; MAPT; neurodevelopment; neurogenetic and neurodegenerative disease; isoform; disease mechanism; dementia

Online: 7 December 2023 (14:56:39 CET)

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Preprint ARTICLE | doi:10.20944/preprints202312.0540.v1

Identification of New c-FLIP Inhibitors to Restore Apoptosis in TRAIL-Resistant Cancer Cells

Katherine Yaacoub, Rémy Pedeux, Pierre Lafite, Ulrich Jarry, Samia ACI-Seche, Pascal Bonnet, Richard Daniellou, Thierry Guillaudeux

Subject: Biology And Life Sciences, Biochemistry And Molecular Biology Keywords: c-FLIP; TRAIL; apoptosis; protein-protein interaction; drug resistance; cancer treatment

Online: 7 December 2023 (14:37:18 CET)

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Preprint ARTICLE | doi:10.20944/preprints202312.0532.v1

Evaluating a 3D Ultrasound Imaging Resolution of Single Transmitter/Receiver with Coding Mask by Extracting Phase Information

Mohammad Syaryadhi, Eiko Nakazawa, Norio Tagawa, Ming Yang

Subject: Computer Science And Mathematics, Signal Processing Keywords: single transducer; coding mask; frequency subband compound; SCM

Online: 7 December 2023 (14:32:26 CET)

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Preprint ARTICLE | doi:10.20944/preprints202312.0535.v1

Unveiling the Probiotic Potential of Streptococcus thermophilus MCC0200: Insights from In-vitro Studies corroborated with Genome Analysis

Neelam Kapse, Vaidehi Pisu, Tanisha Dhakephalkar, Prajakta Margale, Deepa Shetty, Shilpa Wagh, Sumit Dagar, Prashant Dhakephalkar

Subject: Biology And Life Sciences, Life Sciences Keywords: Streptococcus thermophilus; gastrointestinal transit; adhesion; health-promoting; Anti-hypercholesterolemic activity; GRAS; genome

Online: 7 December 2023 (13:58:01 CET)

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Preprint ARTICLE | doi:10.20944/preprints202312.0531.v1

Numerical Study of Hydraulic Percolation in Porous Media Using Two Hydraulic Structures

Albert Willian Faria, Stênio de Sousa Venâncio, Adriano Francisco Siqueira, Estaner Claro Romão

Subject: Engineering, Civil Engineering Keywords: Soil hydraulics; FEM; Laplace equation; steady-state regime.

Online: 7 December 2023 (13:56:14 CET)

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Preprint ARTICLE | doi:10.20944/preprints202312.0537.v1

Autocatalytic Chemical Reaction by a Soluble Biopolymer Derived from Municipal Biowaste

Enzo Montoneri, Elio Padoan, Andrea Baglieri, Francesco Contillo, Matteo Francavilla, Michèle Negre

Subject: Chemistry And Materials Science, Polymers And Plastics Keywords: oxidation; autocatalysis; municipal biowaste; biosurfactants; biopolymers; antifungal agents; anaerobic fermentation; composts

Online: 7 December 2023 (13:55:09 CET)

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Preprint ARTICLE | doi:10.20944/preprints202312.0529.v1

Detection of Extended-Spectrum Beta-Lactamase (ESBL) Producing Enterobacteriaceae from Diseased Broiler Chickens in Lusaka District, Zambia

Chikwanda Chileshe, Misheck Shawa, Nelson Phiri, Joseph Ndebe, Sipho Khumalo, Chie Nakajima, Kajihara Masahiro, Hideaki Higasi, Hirofumi Sawa, Yasuhiko Suzuki, Walter Muleya, Bernard Hang'ombe

Subject: Public Health And Healthcare, Public Health And Health Services Keywords: Enterobacteriaceae, bla_CTX-M, bla_TEM

Online: 7 December 2023 (13:52:04 CET)

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: Poultry products in Zambia form an integral part of the human diet in many households, as they are cheap and easy to produce. The burden of poultry diseases has, however, remained a major challenge. Growing consumer demand for poultry products in Zambia has resulted in non-prudent antimicrobial use on farms, intending to prevent and treat poultry diseases for growth optimization and maximising profits. This cross-sectional study aimed to identify the different types of bacteria causing diseases in chickens in Lusaka and to detect the extended-spectrum-lactamase (ESBL)-encoding genes. We collected 215 samples from 91 diseased chickens at three post-mortem facilities and screened them for gram-negative bacteria. Of these samples, 103 tested positive for various clinically relevant Enterobacteriaceae, including Enterobacter (43/103, 41.7%), Escherichia coli (20/103, 19.4%), Salmonella (10/103, 9.7%), and Shigella (8/103, 7.8%). Other isolated bacteria included Yersinia, Morganella, Proteus, and Klebsiella, which accounted for 21.4%. E. coli, Enterobacter, Salmonella, and Shigella were subjected to antimicrobial susceptibility testing. The results revealed that E. coli, Enterobacter, and shigella were highly resistant to tetracycline, ampicillin, amoxicillin, and trimethoprim-sulfamethoxazole, while Salmonella showed complete susceptibility to all antibiotics. The observed resistance patterns correlated with antimicrobial usage estimated from sales data from a large-scale wholesale and retail company. Six (6/14, 42.9%) E. coli isolates tested positive for bla_CTX-M, whilst eight (8/14, 57.1%) Enterobacter samples tested positive for bla_TEM. Interestingly, four (4/6, 66.7%) of the E. coli isolates carrying bla_CTX-M-positive strains were also positive for bla_TEM. Sanger sequencing of the PCR products revealed that five (5/6,83.3%) of the abovementioned isolates possessed the bla_CTX-M-15 allele. The results suggest the presence of potentially pathogenic ESBL-producing Enterobacteriaceae in poultry, threatening public health. Keywords:. Enterobacteriaceae, bla_CTX-M, bla_TEM

Preprint ARTICLE | doi:10.20944/preprints202312.0534.v1

Eco-Innovative Construction: Integrating Green Roofs within the BIM Framework

Stefano Cascone

Subject: Engineering, Architecture, Building And Construction Keywords: eco‐friendly construction; digital innovation; urban resilience; environmental design; lifecycle analysis

Online: 7 December 2023 (13:44:08 CET)

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This research delves into the integration of green roofs with Building Information Modeling (BIM), a pivotal advancement in sustainable urban construction. Aligning with the United Nations Sustainable Development Goals, particularly Goal 11, the study explores how this integration can address global challenges like climate change and resource depletion. Using the Dynamo Visual Programming Language within Autodesk Revit, the research develops a computational modeling approach for green roofs, focusing on their thermal and structural characteristics under varied environmental conditions. Key findings demonstrate the significant influence of substrate and drainage material combinations on green roofs’ thermal performance, highlighting the need for tailored designs based on climatic conditions. The study also emphasizes the importance of considering structural performance in both dry and saturated conditions for overall building integrity. The research identifies gaps in current practices, such as limited focus on specific green roof materials and reliance on certain software tools, suggesting the need for broader material selection and software adaptability. Future research directions include expanding material selections, exploring diverse environmental conditions, and integrating green roofs with various BIM software platforms. The study's implications extend to stakeholders in the construction industry, offering a framework for architects, urban planners, and policymakers to design and implement green roofs aligned with environmental goals. This work contributes to the field by proposing a novel approach to sustainable construction, integrating ecological design with digital technology, and setting a new benchmark in the integration of green roofs with BIM. By addressing these aspects, the research paves the way for future developments in sustainable urban construction, enhancing the efficiency, sustainability, and resilience of urban communities in line with global sustainability objectives.

Preprint ARTICLE | doi:10.20944/preprints202312.0528.v1

The Protective Role of Canopy Cover against Cork Oak Decline in the Face of Climate Change

João Ribeiro, Constança Camilo-Alves, Nuno Ribeiro

Subject: Environmental And Earth Sciences, Other Keywords: mortality; management; solar radiation; diachronic; climatic resilience

Online: 7 December 2023 (12:46:43 CET)

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Preprint ARTICLE | doi:10.20944/preprints202307.1051.v6

Net Energy Gain from a Berry Geometrical Phase: Low-Energy Perturbations of the Strong Interaction and the QCD Mass Gap

Mark Gibbons

Subject: Physical Sciences, Particle And Field Physics Keywords: Berry geometrical phase; symmetry groups; self-organized criticality; dual superconductivity; scale- and gauge-invariance; hyperbolic curvature; false vacuum; QCD mass gap

Online: 7 December 2023 (12:19:06 CET)

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Preprint ARTICLE | doi:10.20944/preprints202312.0527.v1

Prevalence of Cardiovascular Risks Factors in Cape Verde (Prevcardio.cv) – Santiago Island

Patricia Coelho, Kelly Mascarenhas, Julio Rodrigues, Francisco José Barbas Rodrigues

Subject: Medicine And Pharmacology, Cardiac And Cardiovascular Systems Keywords: Prevalence; Cardiovascular diseases; Risk factors

Online: 7 December 2023 (12:06:19 CET)

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Cerebrovascular diseases represent a significant mortality rate worldwide and constitute a major public health and economic challenge. Many African countries such as Cape Verde are going through an epidemiological transition from communicable to non-communicable diseases, demographic and socioeconomic changes and facing an increase in cerebrocardiovascular diseases associated with increased cardiovascular risk. The present study aimed to identify the prevalence of risk factors that predispose to cardiovascular diseases in adult individuals residing on the island of Santiago. Cross-sectional population-based study with individuals over 18 years of age, of both sexes. Data collection took place in October and November 2021, in all municipalities on the island of Santiago. Individuals with Cape Verdean nationality who stayed abroad for more than one year and who arrived on the island of Santiago less than 30 days ago and individuals with any type of disability that could prevent them from participating in the study were excluded from the study. The sample size was calculated based on the projection of the population of the island of Santiago for the year 2021, according to the appropriate epidemiological model. Sociodemographic data were obtained through the application of a questionnaire containing age, sex, race, weight, height, risk factors (presence of diabetes, dyslipidemia, heredity, physical activity, smoking habits, history of cerebrovascular events, control of weight and blood pressure). RESULTS: Study sample is predominantly female (54.8%), the age group with the largest number was 18-27 years (21%); 42.2% with BMI ≥ 25 kg/m2; 65.1% sedentary; Smoking 7.3% and alcoholism 14.4%; 6.5% with diagnosed heart disease; 19.9% with close family members with cardiac pathology; 2.7% had a stroke, 0.1% had a transient ischemic attack; 0.5% acute myocardial infarction; 23.5% had the periodic habit of assessing blood pressure; 32.6% hypertensive; 4.5% with diabetics. CONCLUSIONS: The study showed that there is a high prevalence of cerebrovascular risk factors on Santiago Island, especially in females. Smoking and alcoholism showed a relationship with males. BMI, physical inactivity, diabetes and dyslipidemia were shown to be related to sex. Hypertension and Diabetes revealed a significant relationship with age group. Alcoholism, smoking, hypercholesterolemia and hypertriglyceridemia maintained a significant relationship with the municipalities.

Preprint REVIEW | doi:10.20944/preprints202312.0526.v1

Economics in Marine Spatial Planning

Ibrahim Issifu, Ilyass Dahmouni, Iria García–Lorenzo, U. Rashid Sumaila

Subject: Environmental And Earth Sciences, Environmental Science Keywords: marine spatial planning; decision support tools; economic analysis

Online: 7 December 2023 (12:02:45 CET)

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Preprint ARTICLE | doi:10.20944/preprints202312.0525.v1

Safety and Efficacy of Tixagevimab and Cilgavimab for Prophylaxis of Covid-19 in a Cohort of Immunosuppressed Rheumatic Patients Treated with Rituximab: A Real-Life Experience

Silvia Peretti, Francesco Bonomi, Elisa Fiorentini, Francesca Bartoli, Gemma Lepri, Silvia Bellando-Randone, Serena Guiducci

Subject: Medicine And Pharmacology, Immunology And Allergy Keywords: SARS-CoV-2, COVID-19, Tixagevimab, Cilgavimab, Rituximab, immunosuppression

Online: 7 December 2023 (11:59:50 CET)

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Preprint ARTICLE | doi:10.20944/preprints202312.0522.v1

Effects of Dietary Plant Protein Replacement by Insect and Poultry By-Product Meals on Liver Health and Serum Metabolites of Sea Bream (Sparus aurata) and Sea Bass (Dicentrarchus labrax)

Valeria Donadelli, Patrizia Di Marco, Alberta Mandich, Maria Grazia Finoia, Gloriana Cardinaletti, Tommaso Petochi, Alessandro Longobardi, Emilio Tibaldi, Giovanna Marino

Subject: Biology And Life Sciences, Aquatic Science Keywords: liver histology; liver index; sustainable feed; poultry by-product meal; Hermetia illucens meal; plant-protein; lipid metabolism; fish welfare; blood biochemistry

Online: 7 December 2023 (11:57:53 CET)

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Preprint ARTICLE | doi:10.20944/preprints202312.0524.v1

Extracellular vesicles from Leishmania (Leishmania) infantum contribute to stimulate the immune response and immunosuppression in hosts with visceral leishmaniasis

Francieli Marinho Carneiro, Allecineia Bispo Da Cruz, Marta Marques Maia, Noemi Nosomi Taniwaki, Ingrid de Siqueira Pereira, Gislene Mitsue Namiyama, Ricardo Gava, Roberto Mitsuyoshi Hiramoto, Bruno Vicente, Victor Midlej, Rafael Meyer Mariante, Vera Lucia Pereira-Chioccola

Subject: Biology And Life Sciences, Parasitology Keywords: Extracellular vesicles; Leishmania (Leishmania) infantum, THP-1 cells, Cytokines, miRNAs

Online: 7 December 2023 (11:42:54 CET)

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Preprint ARTICLE | doi:10.20944/preprints202312.0521.v1

A Gelatin Hydrogel Nonwoven Fabric Enhances Subcutaneous Islet Engraftment in Rats

Ryusuke Saito, Akiko Inagaki, Yasuhiro Nakamura, Takehiro Imura, Norifumi Kanai, Hiroaki Mitsugashira, Yukiko Endo Kumata, Takumi Katano, Shoki Suzuki, Kazuaki Tokodai, Takashi Kamei, Michiaki Unno, Kimiko Watanabe, Yasuhiko Tabata, Masafumi Goto

Subject: Medicine And Pharmacology, Transplantation Keywords: islets; gelatin hydrogel nonwoven fabrics; subcutaneous transplantation; extracellular matrix; neovascularization; rats

Online: 7 December 2023 (11:41:33 CET)

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Preprint ARTICLE | doi:10.20944/preprints202312.0523.v1

Estimation of Validity of A-Mode Ultrasound for Measurements of Subcutaneous Fat Thickness, Muscle Thickness, and MUSCLE quality

Ji-Won Lee, Seung-Ug Hong, Ju-Hee Lee, Sung-Yun Park

Subject: Medicine And Pharmacology, Complementary And Alternative Medicine Keywords: ; amplitude modulation; subcutaneous fat thickness; muscle thickness; muscle quality

Online: 7 December 2023 (11:40:08 CET)

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Preprint ARTICLE | doi:10.20944/preprints202312.0515.v1

Environmental Sustainability Knowledge, Habits and Attitudes Among University and Non-university Population

Shaikha Albedwawi, Mohamed Benhima, Aysha Alsalami, Alreem Alshemeili, Khaled A. El-Tarabily, Seham M. Al Raish

Subject: Environmental And Earth Sciences, Sustainable Science And Technology Keywords: Sustainability; Environmental knowledge; Environmental attitude; Environmental practices; UAE; university

Online: 7 December 2023 (11:25:48 CET)

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Preprint ARTICLE | doi:10.20944/preprints202312.0511.v1

Sterile Fecal Microbiota Transplantation Boosts Anti-Inflammatory T-Cell Response in Ulcerative Colitis Patients

Anton Chechushkov, Pavel Desyukevich, Timir Yakovlev, Lina Al Allaf, Evgeniya Shrainer, Vitalyi Morozov, Nina Tikunova

Subject: Medicine And Pharmacology, Immunology And Allergy Keywords: Ulcerative colitis; Fecal microbiota transplantation; Sterile fecal microbiota transplantation, Regulatory T cells; Immune response

Online: 7 December 2023 (11:25:37 CET)

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Preprint ARTICLE | doi:10.20944/preprints202312.0506.v1

Chronic Morphine Treatment and Antiretroviral Therapy Exacerbate HIV-Distal Sensory Peripheral Neuropathy and Induce Distinct Microbial Alterations in the HIV Tg26 Mouse Model.

Irina Chupikova, Danielle Antoine, Richa Jalodia, Praveen Kumar Singh, Sabita Roy

Subject: Biology And Life Sciences, Neuroscience And Neurology Keywords: HIV-associated pain; neuropathy; opioid use; antiretroviral therapy; gut dysbiosis; Tg26 mouse model

Online: 7 December 2023 (11:24:27 CET)

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Preprint ARTICLE | doi:10.20944/preprints202312.0505.v1

IMMP2L Peptidase Enhances the Structure and Function of Mitochondrial GPD2 Dehydrogenase.

Raymond A Clarke, Hemna Govindaraju, Martina Beretta, Ellen Olzomer, Adam J. Lawther, Adam K Walker, Zhiming Fang, Valsamma Eapen, Tzipi Cohen-Hyams, Murray C. Killingsworth, Wallace J Bridge, Nigel Turner, Khawar Siddiqui

Subject: Biology And Life Sciences, Neuroscience And Neurology Keywords: enzyme structure; mitochondrial dynamics; mitochondrial size; NAD+ biosynthesis; organ mass; behaviour; autism; mitochondrial respiration; non-mitochondrial respiration; lean body mass; glutathione

Online: 7 December 2023 (11:23:15 CET)

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‘Inner mitochondrial membrane peptidase 2 like’ (IMMP2L) is a nuclear encoded mitochondrial peptidase that has been conserved through evolutionary history as has its target enzyme ‘mitochondrial glycerol phosphate dehydrogenase 2’ (GPD2). IMMP2L is known to cleave the mitochondrial transit peptide from GPD2 and another nuclear encoded mitochondrial respiratory related protein cytochrome C1 (CYC1). However, it is not known whether IMMP2L peptidase activates or alters the activity or respiratory related functions of GPD2 or CYC1. Previous investigations found compelling evidence of behavioural change in the Immp2lKD-/- KO mouse and in this study EchoMRI analysis found that many organs of the Immp2lKD-/- KO mouse were smaller and that the KO mouse had significantly less lean mass and overall body weight compared with wildtype littermates (p<0.05). Moreover, all of the organs analysed from the Immp2lKD-/- KO had lower relative levels of mitochondrial reactive oxygen species (mitoROS). The kidneys of the Immp2lKD-/- KO mouse displayed the greatest decrease in mitoROS levels that were over 50% less compared with wildtype litter mates. Mitochondrial respiration was also lower in the kidney of the Immp2lKD-/- KO mouse compared with other tissues when using succinate as the respiratory substrate, whereas respiration was similar to wildtype when glutamate was used as substrate. When glycerol-3-phosphate (G3P) was used as the substrate for Gpd2 we observed ~20% and ~7% respective decreases in respiration in female and male Immp2lKD-/- KO mice over time. Together these findings suggest that the respiratory related functions of mGpd2 and Cyc1 have been compromised to different degrees in different tissues in the Immp2lKD-/- KO mouse. Structural analyses using AlphaFold2-Multimer further predicted that the interaction between Cyc1 and mitochondrial encoded cytochrome b (Cyb) in Complex III had been altered as had the homodimeric structure of the mGpd2 enzyme within the inner mitochondrial membrane of the Immp2lKD-/- KO mouse. mGpd2 functions as an integral component of the glycerol phosphate shuttle (GPS) which positively regulates both mitochondrial respiration and glycolysis. Interestingly, we found that nonmitochondrial respiration (NMR) was also dramatically lowered in the Immp2lKD-/- KO mouse. Primary mouse embryonic fibroblast (MEF) cell lines derived from the Immp2lKD-/- KO mouse displayed a ~27% decrease in total respiration comprised of a ~50% decrease in NMR and a ~12% decrease in total mitochondrial respiration where the latter was consistent with the decreases in substrate specific mitochondrial respiration reported here. This study is the first to report the role of Immp2l in enhancing Gpd2 structure and function, mitochondrial respiration, nonmitochondrial respiration, organ size and homeostasis.

Preprint ARTICLE | doi:10.20944/preprints202312.0516.v1

Development and Validation of a Compressible Reacting Gas-Dynamic Flow Solver for Supersonic Combustion

Anvar Gilmanov, Ponnuthurai Gokulakrishnan, Michael S Klassen

Subject: Engineering, Aerospace Engineering Keywords: Scramjet, Gas Dynamics, Supersonic Combustion, Turbulence-Combustion Interaction, Compressible Solver, High-Speed Flows, Large Eddy Simulation (LES).

Online: 7 December 2023 (11:22:08 CET)

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Preprint ARTICLE | doi:10.20944/preprints202312.0504.v1

Dynamic System Identification via Randomized Stochastic Optimization Under Unknown-but-Bounded Noise

Oleg Granichin, Yury Ivanskiy, Kseniia Denisovna Kopylova

Subject: Computer Science And Mathematics, Mathematics Keywords: mesoscopic observations; randomized stochastic optimization; unknown-but-bounded noise

Online: 7 December 2023 (11:20:42 CET)

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Preprint REVIEW | doi:10.20944/preprints202312.0503.v1

Benefits of Citizen Science for Libraries

Dolores Mumelaš, Alisa Martek

Subject: Social Sciences, Library And Information Sciences Keywords: benefits for libraries; citizen science; libraries; open science

Online: 7 December 2023 (11:19:42 CET)

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Preprint ARTICLE | doi:10.20944/preprints202312.0517.v1

Durable Textile Dyeing/Printing Using Natural Indigo Dyes &Amp; Leaves, and Mayan Inspired Blue Indigo Pigments.

Behary Nemeshwaree, Nicolas Volle

Subject: Chemistry And Materials Science, Materials Science And Technology Keywords: Textiles; Indigo dye and leaves and light -resistant hybrid Mayan indigo pigment; bio-binder; bio-thickener; antimicrobial

Online: 7 December 2023 (11:18:33 CET)

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Preprint ARTICLE | doi:10.20944/preprints202312.0519.v1

Automatic Fire Suppression of Home Automation System Using Graphic System Design

Marimuthu C, Janani V, Kaviyanjali R, Priyanka N, Suba M

Subject: Social Sciences, Safety Research Keywords: Fire Suppression System (FSS); LabVIEW; Arduino microcontroller; Flame and Gas Sensor

Online: 7 December 2023 (11:16:56 CET)

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Preprint ARTICLE | doi:10.20944/preprints202312.0510.v1

Bibliometrics Study of Retail and Consumer Behavior Articles (1971-2022)

Quintessa Huynh

Subject: Business, Economics And Management, Marketing Keywords: retail; consumer behavior; bibliometrics; marketing trends; research community

Online: 7 December 2023 (11:16:13 CET)

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Preprint ARTICLE | doi:10.20944/preprints202312.0520.v1

Crystallization Behavior of Na2O-GeO2-P2O5 Glass System: (Micro)Structural, Electrical, and Dielectric Study

Sara Marijan, Marta Razum, Kristina Sklepić Kerhač, Petr Mošner, Ladislav Koudelka, Jana Pisk, Andrea Moguš-Milanković, Željko Skoko, Luka Pavić

Subject: Chemistry And Materials Science, Ceramics And Composites Keywords: phosphate glasses; phosphate glass-ceramics; controlled crystallization; (micro)structure-property relationship; IR-ATR; PXRD; SEM-EDS; Solid-State Impedance Spectroscopy (SS-IS)

Online: 7 December 2023 (11:01:37 CET)

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Sodium-phosphate-based glass-ceramics (GCs) are promising materials for a wide range of applications, including solid-state sodium-ion batteries, microelectronic packaging substrates, and humidity sensors. This study investigates the impact of 24-hour heat-treatments at varying temperatures on Na-Ge-P glass, with a focus on (micro)structural, electrical, and dielectric properties of prepared GCs. Various techniques such as powder X-ray diffraction (PXRD), infrared spectroscopy-attenuated total reflection (IR-ATR), and scanning electron microscopy-energy dispersive spectroscopy (SEM-EDS) are employed. With the elevation of heat-treatment temperature, crystallinity progressively rises; at 450 °C, the microstructure retains amorphous traits featuring nanometric grains, whereas at 550 °C, heat-treatment results in fully crystallized structures characterized by square-shaped micron-scale grains of NaPO3. The insight into the evaluation of electrical and dielectric properties is provided by Solid-State Impedance Spectroscopy (SS-IS), revealing a strong correlation with the conditions of controlled crystallization and observed (micro)structure. The glass-ceramic heat-treated at 450 °C achieves the highest DC conductivity of 2.30×10–8 Ω–1 cm–1 at 393 K. As the heat-treatment temperature rises, the crystallization of the NaPO3 phase depletes the glass matrix of mobile Na+ ions, resulting in a reduction in DC conductivity. Dielectric parameters also decrease with rising heat-treatment temperature, with the glass-ceramic heat-treated at 550 °C displaying the lowest permittivity of 19.37 and the dielectric loss of 0.008. This research uncovers the intricate relationship between heat-treatment conditions and material properties, emphasizing that controlled crystallization allows for precise modifications to microstructure and phase composition within remaining glassy phase, ultimately facilitating fine-tuning of material properties.

Preprint REVIEW | doi:10.20944/preprints202312.0518.v1

Esters in Industry: An Overview of the Reactors Used in Their Biocatalytic Synthesis

Salvadora Ortega-Requena, Claudia Montiel, Fuensanta Máximo, María Gómez, María Dolores Murcia, Josefa Bastida

Subject: Engineering, Chemical Engineering Keywords: Esters; food industry; cosmetic industry; biocatalysis; immobilized lipase; batch reactor; packed bed reactor; fluidized bed reactor.

Online: 7 December 2023 (10:58:43 CET)

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Preprint ARTICLE | doi:10.20944/preprints202312.0512.v1

Radiographic and Tomographic Study of the Cranial Bones in Children with the Idiopathic type of West syndrome

Ali Al Kaissi, Sergey Ryabykh, Farid Ben Chehida, Hamza Al Kaissi, Vasileios Dougales, Vladimir M. Kenis, Franz Grill

Subject: Medicine And Pharmacology, Neuroscience And Neurology Keywords: Idiopathic type of West syndrome; Cryptogenic epileptic spasms; Cranial bones; Radiology; CT scan

Online: 7 December 2023 (10:41:32 CET)

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.Background: Neither radiological phenotypic characteristics nor reconstruction CT scan to study the cranial contour in children with the so called the idiopathic type of West syndrome has been implemented to reach the etiology understanding. Material and Methods: The basic diagnostic measures and the traditional antiepileptic treatments have been applied to these children in accordance with the conventional protocol of investigations and treatment for children with West syndrome. Boys from three unrelated families were given the diagnosis of idiopathic type of West syndrome. Three boys aged 6,7,9 and three parents (age range of 28-41 year) were included in this study. These children and their parents were referred to our orthopedic departments because of variable skeletal deformities. All showed the history of intellectual disabilities, cryptogenic epileptic spasms and fragmented hypsarrhythmia. Recently, variable forms skeletal deformities of flat foot, torticollis and early onset osteoarthritis. We performed detailed clinical and radiological phenotypic characterization of every affected child, siblings and parents. All affected children underwent whole exome sequence analysis Results: The craniofacial phenotype of all children revealed apparent disruption of development of the cranial bones. Palpation of the skull bones showed unusual palpable boney ridges along different sutural locations. A-7-year-old child showed abnormal bulging over the sagittal suture associated with bilateral boney ridges over the sequamosal sutures. Examining his parents, we noticed a similar skull radiographic abnormality in his mother radiographs. A-10-year-old boy showed an extremely narrow frontal area, facial asymmetry and a well palpable ridge over the lambdoid sutures. 3D reconstruction CT scan confirmed the diagnosis of early closure . His mother showed typical radiographic skull phenotype with a history of postadulthood scoliosis. A- 12-year-old boy showed brachycephaly. Investigating his parents revealed a brachycephalic mother with border line intellegence. We affirm that the pattern of inheritance in the three boys was compatible with X-linked recessive pattern of inheritance . Whole exome sequencing showed non definite phenotype/genotype correlation. Conclusion: The aim of this study was fivefold. First, to refute the common usage of the term idiopathic and we affirm that our findings are Novel. Second, it could be possible that West syndrome is a symptom complex rather than a separate diagnostic entity. Third, to further detect the genetic carrier , we explored the connection between the cranial bones in the children with West syndrome with what is seen in parents.. Fourth, the differences in cranial bones abnormalities among every child and another seems to be heterogeneous. Fifth, it seems that the progressive deceleration in the development of this group of children is highly connected to the progressive closure of the cranial sutures.

Preprint ARTICLE | doi:10.20944/preprints202301.0275.v3

From Problem to Progress: Management of Rodents in Urban and Agricultural Settings in Sub-Saharan Africa.

Ambroise Dalecky, Ibrahima Sow, Abdoul Aziz Ibrahim Danzabarma, Madougou Garba, Jonas Etougbetche, Sylvestre Badou, Henri-Joël Dossou, Cheikh Tidiane Niang, Ousmane Diene, Idrissa Diallo, Mohamed Seyidna Ali Saghiri, Mohamed El Hady Sidatt, Frank Van Steenbergen, Amadou Bocar Bal, Luwieke Bosma, Gualbert Houemenou, Solimane Ag Atteynine, Karmadine Hima, Gauthier Dobigny, Yonas Meheretu

Subject: Biology And Life Sciences, Agricultural Science And Agronomy Keywords: Africa; ecologically based rodent management; field rodents; pest management; rodent control; rodenticides; rodents; synanthropic rodents

Online: 7 December 2023 (10:36:20 CET)

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Preprint ARTICLE | doi:10.20944/preprints202312.0508.v1

SPHN Strategy to Unravel the Semantic Drift Between Versions of Standard Terminologies

Deepak Unni, Vasundra Touré, Philip Krauss, Katrin Crameri, Sabine Österle

Subject: Biology And Life Sciences, Other Keywords: standards, ontologies; semantic drift; versioning; semantic web; FAIR principles

Online: 7 December 2023 (10:28:20 CET)

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Preprint ARTICLE | doi:10.20944/preprints202312.0509.v1

Phytochemical Constituents and Antibacterial Activity of Bark and Flowers Extracts of Four Magnolia Plant Species

Ramona Maria (Iancu) Cristea, Camelia Sava, Ciprian Căpățână, Anastasia Kanellou

Subject: Biology And Life Sciences, Plant Sciences Keywords: Magnolia; polyphenols; phenolic compounds; volatile compounds; antibacterial activity

Online: 7 December 2023 (10:10:56 CET)

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Preprint ARTICLE | doi:10.20944/preprints202312.0507.v1

Typology of Milkfish (Chanos chanos) Farms: Their Operations, Socio-Economic Viability, and Challenges

Edison D. Macusi, Erna S. Macusi, Henzel P. Bongas, Melanie A. Cayacay

Subject: Biology And Life Sciences, Aquatic Science Keywords: climate change impacts; feeding times; mariculture; stocking density; water quality

Online: 7 December 2023 (09:40:13 CET)

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