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Preprint ARTICLE | doi:10.20944/preprints202312.0093.v1

Analytical Experimentations with Midjourney Architectural Virtual Lab: Defining Some Major Current Limits in AI-generated Representations of Islamic Architectural Heritage

Ahmad Sukkar, Mohamed W. Fareed, Moohammed Wasim Yahia, Salem Buhashima Abdalla, Iman Ibrahim, Khaldoun Abdul Karim Senjab

Subject: Engineering, Architecture, Building And Construction Keywords: Islamic architecture; architectural visualization; intangible heritage; text-to-image generation

Online: 1 December 2023 (21:29:02 CET)

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Preprint REVIEW | doi:10.20944/preprints202312.0091.v1

Recent Records on Bacterial Opportunistic Infections via the Dietary Route

Franca Rossi, Serena Santonicola, Carmela Amadoro, Lucio Marino, Giampaolo Colavita

Subject: Biology And Life Sciences, Immunology And Microbiology Keywords: dietary route; bacteria; opportunistic pathogens; recent infection records; risk factors

Online: 1 December 2023 (21:26:27 CET)

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Preprint REVIEW | doi:10.20944/preprints202312.0098.v1

The Laboratory Diagnosis of Malaria: A Focus on the Diagnostic Assays in Non‐Endemic Areas

Adriana Calderaro, Giovanna Piccolo, Carlo Chezzi

Subject: Public Health And Healthcare, Public Health And Health Services Keywords: Plasmodium sp.; imported malaria; diagnosis; molecular methods; polymerase chain reaction; RTD; microscopy; flow cytometry

Online: 1 December 2023 (16:44:42 CET)

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Preprint ARTICLE | doi:10.20944/preprints202312.0096.v1

Innovative Production of Phosphoric Acid-Hydrolyzed Chitin Nanocrystals for Pickering Emulsion Stabilization

Xiaoxue Jia, Peihua Ma, Kim Shi-Yun Taylor, Yiyang He, Yimin Mao, And Qin Wang

Subject: Chemistry And Materials Science, Nanotechnology Keywords: Chitin nanocrystals; Phosphoric acid; Pickering emulsion; Emulsion stability; Microstructure; Rheological property

Online: 1 December 2023 (16:35:20 CET)

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Preprint REVIEW | doi:10.20944/preprints202312.0095.v1

Hematological Neoplasm with Eosinophilia

Rosario M Morales-Camacho, Teresa Caballero-Velázquez, Juan José Borrero, Ricardo Bernal, Concepción Prats-Martín

Subject: Medicine And Pharmacology, Hematology Keywords: Eosinophilia,; hematological neoplasm; myeloid/lymphoid neoplasm with eosinophilia; tyrosine kinase fusion genes; acute leukemia

Online: 1 December 2023 (16:34:12 CET)

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Preprint ARTICLE | doi:10.20944/preprints202312.0094.v1

Hybrid Maker Spaces and the Circular City: A Case Study of Leuven, Belgium

Ingrid Schroder, Reham Elwakil, Koen Steemers

Subject: Arts And Humanities, Architecture Keywords: maker spaces; circular cities; urban manufacturing; circular economy; case study; Leuven; Maakleerplek

Online: 1 December 2023 (16:33:15 CET)

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Preprint ARTICLE | doi:10.20944/preprints202312.0097.v1

Novel Nanostructured Pd/Co‐Alumina Materials for the Catalytic Oxidation of Atmospheric Pollutants

Eleni F. Iliopoulou, Eleni Pachatouridou, Angelos A. Lappas

Subject: Chemistry And Materials Science, Other Keywords: CO oxidation; Methanol oxidation; Spray impregnation; Core-shell; Cobalt oxide; Palladium

Online: 1 December 2023 (16:32:29 CET)

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Preprint ARTICLE | doi:10.20944/preprints202312.0092.v1

Data Augmentation for Regression Machine Learning Problems in High Dimensions

Clara Guilhaumon, Nicolas Hascoët, Francisco Chinesta, Marc Lavarde, Fatima Daim

Subject: Computer Science And Mathematics, Artificial Intelligence And Machine Learning Keywords: Active Learning; Design of experiments; Regression; s-PGD

Online: 1 December 2023 (15:04:37 CET)

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Preprint BRIEF REPORT | doi:10.20944/preprints202312.0089.v1

Allele Frequencies and the Probability of Identity for 18 STR Loci Generated via the Canine GenotypesTM Panel 2.1 Kit in Golden Retriever, Miniature Dachshund, and Shiba Inu Groups for Forensic Applications

Fubuki Kunita, Chihiro Udagawa, Takeshi Inagaki, Hideto Suzuki, Makoto Bonkobara, Toshinori Omi

Subject: Biology And Life Sciences, Animal Science, Veterinary Science And Zoology Keywords: dog DNA identification; STR; golden retriever; miniature dachshunds; shiba inus

Online: 1 December 2023 (13:37:35 CET)

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Preprint ARTICLE | doi:10.20944/preprints202312.0090.v1

Green Synthesis, Characterization and Antibacterial Activity of Gold and Copper Nanoparticles from Lannea discolor (Sond.) Engl

Unarine Rambau, Nndivhaleni Anox Masevhe, Nneka Augustina Akwu, Amidou Samie

Subject: Biology And Life Sciences, Plant Sciences Keywords: copper nanoparticles; gold nanoflowers; green nanoparticle synthesis; Lannea discolor; plant extracts

Online: 1 December 2023 (13:36:53 CET)

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Preprint ARTICLE | doi:10.20944/preprints202312.0082.v1

The Long Road from Religious and Ethical Traditions to Welfare of Invertebrates

Jennifer A. Mather

Subject: Biology And Life Sciences, Animal Science, Veterinary Science And Zoology Keywords: Invertebrates; welfare; ethics; religious values; moral standing; sentience

Online: 1 December 2023 (13:36:15 CET)

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Preprint ARTICLE | doi:10.20944/preprints202312.0084.v1

Synthesis and Characterization of Metal Oxide Nanoparticles Anchored Carbon as Hybrid Adsorbents for Effective Heavy Metals-Uptake from Wastewater

Abdullah G ALanazi, Mohamed A Habila, Zeid A ALOthman, Ahmed Yacine Badjah-Hadj-Ahmed

Subject: Chemistry And Materials Science, Applied Chemistry Keywords: hybrid materials; zinc oxide nanoparticles; carbon; iron (III) oxide nanoparticle; adsorption; ki-netic and equilibrium studies

Online: 1 December 2023 (13:35:24 CET)

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Preprint ARTICLE | doi:10.20944/preprints202312.0086.v1

Wood and Cable-Based Variable Tilt Stilt-Mounted Solar Photovoltaic Racking System

Uzair Jamil, Nicholas Vandewetering, Seyyed Ali Sadat, Joshua M. Pearce

Subject: Engineering, Energy And Fuel Technology Keywords: open source; racking; biomaterials; wood; photovoltaic; mechanical design; balance of systems; renewable energy; solar energy

Online: 1 December 2023 (13:34:18 CET)

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Preprint ARTICLE | doi:10.20944/preprints202312.0088.v1

The Anticancer Effects of Moringa oleifera Peptides on the Erythropoietin-Producing Hepatocellular Receptor (EphB4) Were Predicted In Silico

Mónica Andrea Valdez-Solana, Claudia Avitia-Domínguez, Alfredo Téllez Valencia, Erick Sierra-Campos

Subject: Biology And Life Sciences, Biochemistry And Molecular Biology Keywords: Moringa oleifera; anticancer peptides; EphB4; Bioinformatics.

Online: 1 December 2023 (13:32:59 CET)

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Preprint ARTICLE | doi:10.20944/preprints202312.0080.v1

Underlay Loosely Coupled Model for Public Safety Networks based on D2D

Wajdi Elleuch

Subject: Computer Science And Mathematics, Computer Networks And Communications Keywords: Public Safety Network; D2D; Proximity Service; underlay networks; loosely coupled 22 model; network simulation

Online: 1 December 2023 (13:32:14 CET)

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Preprint ARTICLE | doi:10.20944/preprints202312.0077.v1

Investigation of Inter- and Intra-Chain Interactions in Mixtures of Long-Chain Hydrocarbons with Relations to Plant Cuticular Waxes: Using n-Nonadecane and 1-Octadecanol Mixer as examples

Wentao Guo, Yi Xing, Wei Su, Changjiang Hou, Guotao Li

Subject: Chemistry And Materials Science, Materials Science And Technology Keywords: Alkane; Alkanol; Crystallization; Binary system; Phase transition; Plant; Hydrocarbons.

Online: 1 December 2023 (13:30:59 CET)

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Preprint REVIEW | doi:10.20944/preprints202312.0079.v1

Verification of Electromagnetic Transients That Influence the Voltage Stability of the Intelligent Microgrid with Virtual Im-Pedance Enhanced with Particle Swarm Optimization

Vicente Tiburcio Dos Santos Júnior

Subject: Engineering, Electrical And Electronic Engineering Keywords: microgrid; re-synchronization; voltage stability; electric vehicles; electric vehicles chargers; virtual impedance; particle swarm optimization.

Online: 1 December 2023 (13:30:17 CET)

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In this research, the concept of the instability of tension in Microgrid still becomes the focus of study and purpose. Scrutinously, First-Swing Instability occurs in the system in noted changes with properties of making the system unstable or restore to a state of stability. The latter calls itself as a phenomenon of re-synchronization. Allied to aspects of system instability, it is evident that by connecting fast electric chargers for battery-electric vehicles to the distribution system from microgrids, they increase the necessary basic electrical charges and reduce the stability of the electrical energy system. Transient electrical currents have the characteristic of severely impacting microgrids not prepared in connected states or island of the main system. The occurrences of the electromagnetic incompatibility of the inrush current, due to their unpredictability and intermittent characteristic, have complex identification studies. With the elevation of electricity demand by battery-electric vehicle chargers, concerns about the effects of the integration of the electricity grid increase proportionally. The research described in this article emphasizes the influence of fast chargers’ initialization on the power variation related to the re-synchronization phenomenon and its mitigation of the stability of electricity microgrid. An optimization algorithm based on particle swarm optimization (PSO) implements the development of virtual impedances. The PSO optimization algorithm analyzes all possible operating points and aims to maximize the stability index of microgrid, maintaining reactive energy incompatibilities at the minimum level supported. The fractional objective function facilitates the service to these goals simultaneously. The optimization algorithm is implemented in a case study and the corresponding virtual impedance is incorporated into the microgrid. Voltage levels are verified as a condition in the optimization process, comparing system effectiveness.

Preprint ARTICLE | doi:10.20944/preprints202312.0087.v1

Linking the Neoproterozoic to Early Paleozoic Belts Bordering the West African and Amazonian Cratons

Michel Villeneuve, Camille Rossignol

Subject: Environmental And Earth Sciences, Geophysics And Geology Keywords: West African fold belts; Brazilian belts; Neoproterozoic orogens; Early Paleozoic; Gondwana; Correlations

Online: 1 December 2023 (13:26:46 CET)

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Preprint COMMUNICATION | doi:10.20944/preprints202312.0083.v1

Exploring the Potential Role of Hypericin in Targeting PIM1 for Cancer Research

IVAN VITO FERRARI

Subject: Medicine And Pharmacology, Oncology And Oncogenics Keywords: PIM1 protein kinase; hypericin; docking analysis; cancer

Online: 1 December 2023 (11:47:15 CET)

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Preprint ARTICLE | doi:10.20944/preprints202312.0078.v1

Agricultural Yield Responses to Climate Variabilities in West Africa: A Food Supply and Demand Analysis

Martin Schultze, Stephen Kankam, Safiétou Sanfo, Christine Fürst

Subject: Environmental And Earth Sciences, Geography Keywords: agriculture; climate variability; crop yield; food supply and demand analysis; West Africa; Ghana; Burkina Faso

Online: 1 December 2023 (11:29:04 CET)

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Agricultural productivity is expected to decrease under changing climate conditions that correspond to the stability of West African food systems. Although numerous studies evaluated food production gaps or impacts of climate variability on crop yields, many uncertainties are associated with climate extremes, but also rapid population growth and the corresponding dietary lifestyle determine farming activities. Here, we present a food supply and demand analysis based on the relationship between climate change, crop production, as well as population growth in three experimental sites from southwestern Burkina Faso to southwestern Ghana. The method consists of a tiered approach that encompassed a statistical analysis of historical climate as well as agricultural time series using boxplots and a trend test by Mann-Kendall. Food balance sheets were calculated by estimating the demand using a population growth model linked to food supply with local consumption patterns. Results of the boxplot analysis revealed for the majority of climate time series light to strong right-skewed distributions with either a few heavy rainfall or hot temperature events. We found almost insignificant rainfall and temperature trends for both sites in the Sudano-Guinean savannah. The rainfall regime of southwestern Ghana indicated an insignificant upward or downward trend while the temperature significantly increased over time. Crop yield boxplots demonstrated mainly right-skewed distributions for cereals, legumes and tubers as well as cash crops such as cotton. Backed by the Mann-Kendall test, maize and sorghum significantly enhanced in both study areas of the Sudano-Guinean savannah. Southwestern Ghana depicted a different crop pattern where cassava and plantain showed a strong upward trend at a confidence level of 1%. The grouped food balances sheets across the regions illustrated a surplus for the Sudano-Guinean savannah ranging from 221.2 megatons (Mt) to 4,846.77 Mt while southwestern Ghana exhibited a deficit between -193.33 Mt and -16,188.82 Mt. Despite a growing yield of various crops, food demand outpaces the regional production. Hence, it is recommended to focus on a larger array of commodities, imports and marketing of farm products.

Preprint REVIEW | doi:10.20944/preprints202312.0081.v1

Relationship between Biochemical Pathways and Non-Coding RNAs Involved in the Progression of Diabetic Retinopathy

Małgorzata Mrowicka, Jerzy Mrowicki, Ireneusz Majsterek

Subject: Medicine And Pharmacology, Ophthalmology Keywords: diabetic retinopathy; biochemical pathways; oxidative stress; ncRNAs; biomarkers

Online: 1 December 2023 (11:27:36 CET)

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Preprint ARTICLE | doi:10.20944/preprints202312.0066.v1

ControlFace: Feature Disentangling for Controllable Face Swapping

Xuehai Zhang, Wenbo Zhou, Kunlin Liu, Hao Tang, Zhenyu Zhang, Weiming Zhang, Nenghai Yu

Subject: Computer Science And Mathematics, Computer Vision And Graphics Keywords: face swapping; feature disentanglement; semantic hierarchy-based feature fusion; controllable identity feature transfer

Online: 1 December 2023 (10:47:32 CET)

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Preprint CASE REPORT | doi:10.20944/preprints202311.1995.v2

Vram Flap for Pelvic Floor Reconstruction after Pelvic Exenteration and Abdominoperineal Excision

Ionut Flaviu Faur, Adelina Clim, Amadeus Dobrescu, Catalin Prodan, Rami Hajjar, Paul Pasca, Marco Capitanio, Ionel Nati, Cristi Tarta, Alexandru Isaic, George Noditi, Bogdan Totolici, Ciprian Duta, Gabriel Lazar

Subject: Medicine And Pharmacology, Surgery Keywords: vertical rectus abdominis muscle flap; perineal wound; pelvic exenteration; squamosal cell carcinoma of the uterine cervix; reconstruction

Online: 1 December 2023 (10:46:42 CET)

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Preprint ARTICLE | doi:10.20944/preprints202312.0069.v1

Evaluating STEM Lecturers ‘Experiences with Digital Assessments and Continuity of Digital Transformation in Higher Education

Innocent Zitha, Georgina Mokganya, Orifha Sinthumule

Subject: Social Sciences, Education Keywords: Connectivism; Learning Management Systems; affordances; technological resistance; Moodle; transformative pedagogy

Online: 1 December 2023 (10:45:30 CET)

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There are understandable signs that the COVID-19 pandemic has had a straining impact on the higher education sector in South Africa and the far reaches of the world. However, the necessary preparation and skills of lecturers and students are considered a major problem when integrating online education into teaching. The aim of the paper is to examine (Science, Technology, Engineering, Mathematics) STEM lecturers' experiences with digital assessments and perspectives on the continuity of digital transformation in the higher education sector in the post-COVID-19 era at one of South Africa’s rural universities. In 2022, a survey of ten (10) lecturers was conducted and the reports were also consulted by four (4) e-learning practitioners to obtain their views on the use of online learning and contact courses in the post-pandemic period. A qualitative research approach was used to understand the puzzling issues faced by STEM lecturers at a previously disadvantaged institution in Limpopo Province. The results of this study show that there is a puzzling conundrum that hinders the integration of effective online learning. Furthermore, online education as the new normal in the post-COVID-19 era seems unattainable due to extremely complex and difficult-to-understand mathematical symbols. Software and tools proved to be limitations in terms of establishing an interactive learning environment for students and lecturers on online learning platforms. Lecturers’ use of learning and teaching platforms deteriorated due to numerous unknown challenges, but also the tightening of COVID-19 restrictions. Furthermore, the results showed that science and mathematics lecturers believe that contact learning remains irreplaceable across generations and eras as some are not technology enthusiasts. This paper recommends that the lack of technological systems as well as technological resistance and reluctance to adopt transformative pedagogy and innovative practices should not be viewed as a thorny issue to end the dominance of online education in STEM courses.

Preprint REVIEW | doi:10.20944/preprints202311.0073.v2

Cellular Processes Induced by HSV-1 Infections in Vestibular Neuritis

Zhengdong Zhao, Xiaozhou Liu, Yanjun Zong, Xinyu Shi, Yu Sun

Subject: Biology And Life Sciences, Virology Keywords: Keywords: Herpesvirus; Herpes Simplex virus Type 1; Human cytomegalovirus; Vestibular neuritis; Celler processes

Online: 1 December 2023 (10:16:05 CET)

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Preprint ARTICLE | doi:10.20944/preprints202312.0004.v1

The Comminution of Chert Gravel by Microwave Irradiation for Reuse Optimization of Quarry Areas

Mark Tzibulsky, Vladimir Frid

Subject: Environmental And Earth Sciences, Environmental Science Keywords: microwave irradiation; rock comminution, quartz response, chert gravel, reuse of quarry area

Online: 1 December 2023 (10:15:13 CET)

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Preprint ARTICLE | doi:10.20944/preprints202311.2010.v1

Aids In Spanish Penitentiary Institutions through the Nurse's Point of View

Enrique J. Vera-Remartnez, Jose Antonio Zafra Agea, Julio Garcia-Guerrero, Maria Pilar Molés-Julio

Subject: Public Health And Healthcare, Other Keywords: Síndrome de inmunodeficiencia adquirida; enfermería; prisiones; España.

Online: 1 December 2023 (10:14:28 CET)

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Preprint ARTICLE | doi:10.20944/preprints202312.0071.v1

Facebook Users’ Attitudes towards Human Papillomavirus Vaccination in South Africa

Edison Johannes Mavundza, Anelisa Jaca, Duduzile Ndwandwe, Sara Cooper

Subject: Public Health And Healthcare, Public Health And Health Services Keywords: human papillomavirus; vaccination; social media; Facebook; South Africa

Online: 1 December 2023 (10:13:38 CET)

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Preprint REVIEW | doi:10.20944/preprints202312.0064.v1

Application of Through Glass Via (TGV) Technology for Sensors Manufacturing and Packaging

Chen Yu, Shaocheng Wu, Yi Zhong, Rongbin Xu, Tian Yu, Jin Zhao, Daquan Yu

Subject: Engineering, Electrical And Electronic Engineering Keywords: Through glass via; MEMS sensors; Sensor manufacturing; Sensor packaging

Online: 1 December 2023 (10:12:12 CET)

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Preprint ARTICLE | doi:10.20944/preprints202312.0065.v1

RNA Pol II Assembly Affects ncRNA Expression

Ana I. Garrido-Godino, Ishaan Gupta, Vicent Pelechano, Francisco Navarro

Subject: Biology And Life Sciences, Biochemistry And Molecular Biology Keywords: transcription; RNA polymerases; ncRNAs; RNA polymerases assembly; Rtr1 CTD phosphatase; NNS termination; exosome; CUTs; SUTs; Saccharomyces cerevisiae

Online: 1 December 2023 (10:10:30 CET)

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Preprint REVIEW | doi:10.20944/preprints202312.0067.v1

The Use of Fungi of the Trichoderma Genus in Anaerobic Digestion: A Review

Adrianna Kubiak, Agnieszka A. Pilarska, Agnieszka Wolna-Maruwka, Alicja Niewiadomska, Katarzyna Panasiewicz

Subject: Environmental And Earth Sciences, Sustainable Science And Technology Keywords: anaerobic digestion; Trichoderma sp.; biogas, biomethane; lignocellulosic biomass; waste plant biomass; pretreatment methods; biological pretreatment methods; digestate; organic carrier

Online: 1 December 2023 (10:08:42 CET)

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Preprint REVIEW | doi:10.20944/preprints202312.0063.v1

Hydrogen Storage System Attained by HCOOH-CO2 Couple: Recent Developments in Carbon-Based Heterogeneous Catalysts

P. Riquelme-García, M. Navlani-García, D. Cazorla-Amorós

Subject: Chemistry And Materials Science, Materials Science And Technology Keywords: Hydrogen storage; formic acid; CO2; carbon materials; heterogeneous catalysts

Online: 1 December 2023 (10:06:51 CET)

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Preprint REVIEW | doi:10.20944/preprints202312.0068.v1

Solid Acid-Base Catalysts Based on Layered Double Hydroxides Applied for Green Catalytic Transformations

Xiaolu You, Lishi Chen, Shan He, Guiju Zhang

Subject: Chemistry And Materials Science, Chemical Engineering Keywords: Acid-base catalysis; Green catalytic transformation; Layered double hydroxides; Heterogeneous catalysis; Applications

Online: 1 December 2023 (10:03:56 CET)

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Preprint ARTICLE | doi:10.20944/preprints202312.0060.v1

Ethical Aspect for Public Officers

MALIK M.A.FAKRON

Subject: Arts And Humanities, Philosophy Keywords: ethics; values; public officers; evaluation; public institution; stakeholders

Online: 1 December 2023 (09:23:17 CET)

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Preprint REVIEW | doi:10.20944/preprints202312.0057.v1

The Genetic Landscape of Sleep Disorders in Parkinson’s Disease

Kallirhoe Kalinderi, Vasileios Papaliagkas, Liana Fidani

Subject: Medicine And Pharmacology, Neuroscience And Neurology Keywords: Parkinson’ s disease; sleep disorders; GBA; Parkin

Online: 1 December 2023 (09:17:21 CET)

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Preprint ARTICLE | doi:10.20944/preprints202312.0062.v1

The Effect of Varying Air Flow Solar Collector on the Quality of Arabica Coffee Beans

Parulian Siagian, Farel Hasiholan Napitupulu, Himsar Ambarita, Hendrik Voice Sihombing, Yogie Probo Sibagariang, Horas Sotardodo Siagian

Subject: Engineering, Mechanical Engineering Keywords: coffee; air flow; forced convection; temperature; quality

Online: 1 December 2023 (08:19:28 CET)

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Different coffee drying technologies face complex task in ensuring an acceptable final seed moisture content. Drying technology of agricultural commodities aims to maintain and improve the quality of the agricultural products themselves. In addition to maintaining quality, especially from other bacterial attacks, it can last for a long time before further processing. Coffee commodities are promising for the welfare of coffee farmers. Drying technology plays a major role in determining the quality of coffee. Various drying models are applied including the traditional model that until now is still applied, direct drying under solar radiation. However, this drying process is less hygienic and requires a large area. Thus, one of the drying technologies that can accelerate drying time is to vary the air flow in the drying chamber so that the coffee can be determined to reduce the water content with a certain temperature. In this study, it was found that the moisture content of coffee beans dried using a dryer on air flow with variations of velocity in solar collector 1 (DB1) air velocity of 1.0m/s obtained the final mass = 732.249 gr, solar collector 2 (DB2) with air velocity 1.5 m/s obtained the final mass = 774.70 gr, solar collector 3 (DB3) with air velocity 2.0 m/s obtained the final mass = 855.10 gr, solar collector 4 (DB4) with air velocity 2.5 m/s obtained the final mass = 745.79 gr, and solar collector 5 (DB5) with air velocity 3.0 m/s obtained the final mass = 786.40 gr. Water Content DB1=12.0%, DB2=13.6%, DB3=18.5%, DB4=12.9% and DB5=15.2%. The time required for 25 hours with a maximum radiation of 586.9 w/m2, total heat utilized from solar radiation in 3 days =16.663128 MJ/m2. from the initial weight of 1500gr coffee bean samples and dried in five solar collectors with parallel simultaneously. The evaporated water content DB1=51.18%, DB2=48.35%, DB3=42.96%, DB4=50.28% and DB5=47.57%. Based on this research, it was found that the most optimum quality of coffee was by using solar collector 2 (DB2), namely with air flow of 1.5 m/s with average temperature in the drying box DB2=43.68°C, with the quality content of the coffee, Protein content=12.2%, Carbohydrate=22.8% and Free Fatty Acid (ALB) content=0.05%.

Preprint ARTICLE | doi:10.20944/preprints202312.0061.v1

Global Non-existence of a Coupled Parabolic-Hyperbolic System of Thermoelastic Type with History

Jorge Alfredo Esquivel-Avila

Subject: Computer Science And Mathematics, Mathematics Keywords: blow up; evolution equations; parabolic-hyperbolic system; thermoelasticity

Online: 1 December 2023 (08:18:01 CET)

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Preprint ARTICLE | doi:10.20944/preprints202312.0011.v1

Enhancing Fingerprint Forensics: A Comprehensive Study of Gender Classification Based on Advanced Data-Centric AI Approaches and Multi-Database Analysis

Assaf Spanier, Dor Steiner, Navon Sahalo, Yoel Abecassis, Dan Ziv, Ido Hefetz, Shimon Kimchi

Subject: Computer Science And Mathematics, Artificial Intelligence And Machine Learning Keywords: deep learning; fingerprint; Gender classification; Data-Centric AI (DCAI); forensic science; Partial or low-quality fingerprint

Online: 1 December 2023 (08:15:23 CET)

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Preprint REVIEW | doi:10.20944/preprints202312.0052.v1

The Past, Present, Future: Pathophysiology, Diagnosis, and Treatment of Human Skin Diseases

Niki Ebrahimnejad, Heidi Goodarzi

Subject: Biology And Life Sciences, Anatomy And Physiology Keywords: skin disease; skin cancer; diagnostics; treatments

Online: 1 December 2023 (08:12:16 CET)

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Preprint ARTICLE | doi:10.20944/preprints202312.0036.v1

Application of Artificial Intelligence and Machine Learning for the Prediction of Interbody Cage Height and Postoperative Alignment in Transforaminal Lumbar Interbody Fusion

Anh Tuan Bui, Hieu Le, Tung Thanh Hoang, Giam Minh Trinh, Hao-Chiang Shao, Pei-I Tsai, Kuan-Jen Chen, Kevin Li-Chun Hsieh, E-Wen Huang, Ching-Chi Hsu, Mathew Mathew, Ching-Yu Lee, Po-Yao Wang, Tsung-Jen Huang, Meng-Huang Wu

Subject: Medicine And Pharmacology, Surgery Keywords: Spinal fusion; Interbody cage; Sagittal balance; Artificial intelligence; Machine learning; Spinal parameters

Online: 1 December 2023 (08:12:03 CET)

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Preprint REVIEW | doi:10.20944/preprints202312.0041.v1

Harnessing Nanotechnology for Improved Treatment for Inflammatory Cardiovascular Disorders

Muhammad Fareed, Carola Yvette Förster, Sergey Shityakov

Subject: Medicine And Pharmacology, Cardiac And Cardiovascular Systems Keywords: Cardiovascular disease (CVD); biomedicine; nanotechnology; drug delivery

Online: 1 December 2023 (08:10:55 CET)

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Preprint ARTICLE | doi:10.20944/preprints202312.0025.v1

A Data-Driven Approach to Team Formation in Software Engineering Based on Personality Traits

Jan Vasiljević, Dejan Lavbič

Subject: Computer Science And Mathematics, Computer Science Keywords: team formation; personality traits; software engineering; data-driven approach; simulated annealing

Online: 1 December 2023 (08:10:35 CET)

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Preprint REVIEW | doi:10.20944/preprints202312.0031.v1

Calcium Signaling and the Response to Heat Shock in Crop Plants

Xinmiao Kang, Liqun Zhao, Xiaotong Liu

Subject: Biology And Life Sciences, Plant Sciences Keywords: crop yield; thermotolerance; Ca2+ signaling

Online: 1 December 2023 (08:10:17 CET)

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Preprint ARTICLE | doi:10.20944/preprints202312.0049.v1

A Systematic Series Development and Calm Water Resistance Prediction for a Fast Catamaran Ferry Utilizing Machine Learning Tools

Amin Nazemian, Evangelos Boulougouris, Myo Zin Aung

Subject: Engineering, Marine Engineering Keywords: Systematic series; Machine learning; Lackenby variation method; Self-blending method; Panel method

Online: 1 December 2023 (08:09:59 CET)

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Preprint ARTICLE | doi:10.20944/preprints202312.0046.v1

Effectiveness of Scrum Master in Agile Projects

Muhammad Hamza

Subject: Computer Science And Mathematics, Software Keywords: Scrum Master Role-Effectiveness; Iterative Approach

Online: 1 December 2023 (08:09:43 CET)

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Preprint ARTICLE | doi:10.20944/preprints202312.0035.v1

Clinical Impact of Comprehensive Molecular Profiling in Adolescent and Young Adults with Sarcoma

Eden C Andrew, Jeremy Lewin, Jayesh Desai, Lisa Orme, Anne Hamilton, Susie Bae, Wenying Zhu, Shannon Nicolson, Leila N Varghese, Camilla B Mitchell, Joseph H.A. Vissers, Huiling Xu, Sean M Grimmond, Stephen B Fox, Stephen J Luen

Subject: Medicine And Pharmacology, Oncology And Oncogenics Keywords: Adolescents and young adults (AYA) cancer; molecular profiling; precision oncology; genomics; whole genome sequencing; next-generation sequencing; sarcoma; diagnostic biomarkers

Online: 1 December 2023 (08:09:28 CET)

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Preprint ARTICLE | doi:10.20944/preprints202312.0043.v1

Synergistic Effects of Zeolite-Sewage Sludge Blends and Reduced Nitrogen Doses on Soil Carbon Fractions, Nutrient Index, and Plant Growth of Rice in Controlled Environment

Jencymol Thomas, Arun Kumar K, Balkrishna S Bhople, Vijay Kant Singh, Sanjat K. Kumar Sahu, Jayanthi J, Omkar Singh, Eman A. Mahmoud, Fazal Ullah, Ihab Mohamed Moussa, Mohamed Al-Yafrasi, Hosam O Elansary

Subject: Environmental And Earth Sciences, Soil Science Keywords: Zeolite; Sewage Sludge; Nutrient Use Efficiency; Plant Growth Response; Recommended Dose of Fertilizer; Principal Component Analysis

Online: 1 December 2023 (08:06:53 CET)

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: Alluvial soils naturally possess abundant soil nutrients. Nevertheless, excessive nitrogen addition and inappropriate use of nitrogen fertilizers lead to conditions where soil nutrients become immo-bilized, ultimately reducing productivity. This study investigates the potential of natural nano-material zeolite which is important land resources to improve nutrient utilization efficiency and mitigate the harmful effects of excessive fertilizer application. Specifically, the research ex-plores the incorporation of clinoptilolite zeolite and processed sewage sludge blends, alongside reduced recommended nitrogen fertilizer doses, to evaluate their impact on soil quality and plant growth. A greenhouse experiment was conducted (three-year study), comprising eight treatments with varying proportions of zeolite and sewage sludge. The efficacy of these treatments in en-hancing soil carbon pools, nutrient indices, and plant growth responses was assessed. Results in-dicate that a combination of 50% recommended fertilizer dose, 4-6% zeolite, and 5-10% sewage sludge significantly improved multiple aspects of plant growth, including leaves, tillers, culms, and panicles, leading to increased straw and grain yields. The addition of 6% zeolite in conjunc-tion with sewage sludge positively influenced plant tillering capacity. Certain treatment combina-tions exhibited a greater impact on plant height at different growth stages. For example, the treatment with 75% recommended fertilizer dose, 4% zeolite, and 5% sewage sludge significantly affected plant height at 40 and 55 days after treatment. Additionally, the combination of 50% recommended fertilizer dose, 6% zeolite, and 10% sewage sludge promoted plant height, carbon levels, and various yield parameters in later stages. Principal component analysis effectively dis-tinguished treatments incorporating zeolite and sewage sludge based on plant responses. The combination of 6% zeolite and 10% sewage sludge, along with a 50% recommended fertilizer dose, positively influenced soil carbon fractions, nutrient levels, and the growth response of rice plants.

Preprint CASE REPORT | doi:10.20944/preprints202311.1995.v1

VRAM flap for pelvic floor reconstruction after pelvic exenteration and abdominoperineal excision

Ionut Flaviu Faur, Adelina Clim, Amadeus Dobrescu, Catalin Prodan, Rami Hajjar, Paul Pasca, Marco Capitanio, Ionel Nati, Cristi Tarta, Alexandru Isaic, George Noditi, Bogdan Totolici, Ciprian Duta, Gabriel Lazar

Subject: Medicine And Pharmacology, Surgery Keywords: vertical rectus abdominis muscle flap; perineal wound; pelvic exenteration; squamosal cell carcinoma of the uterine cervix; reconstruction

Online: 1 December 2023 (08:06:39 CET)

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Preprint ARTICLE | doi:10.20944/preprints202312.0012.v1

The Effect of Magnetically Induced Local Structure and Volume Fraction on the Electromagnetic Properties of Elastomer Samples with Ferrofluid Droplet Inserts

Catalin Nicolae Marin, Iosif Malaescu

Subject: Chemistry And Materials Science, Ceramics And Composites Keywords: elastomer; ferrofluid; complex magnetic permeability; complex dielectric permittivity; electrical conductivity

Online: 1 December 2023 (08:05:15 CET)

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Preprint ARTICLE | doi:10.20944/preprints202311.1988.v1

EEUR-Net: End-to-End Optimization of Undersampling and Reconstruction Network for 3D Magnetic Resonance Imaging

Quan Dong, Yiming Liu, Jing Xiao, Yanwei Pang

Subject: Computer Science And Mathematics, Artificial Intelligence And Machine Learning Keywords: deep learning; 3D MRI; k-space undersampling; image reconstruction; 3D U-Net

Online: 1 December 2023 (08:03:45 CET)

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Preprint ARTICLE | doi:10.20944/preprints202312.0038.v1

Experimental Study of Cold Dense Nuclear Matter

Maria Patsyuk, Timur Atovullaev, Goran Johansson, Dmitriy Klimanskiy, Vasilisa Lenivenko, Sergey Nepochatykh, Eli Piasetzky

Subject: Physical Sciences, Nuclear And High Energy Physics Keywords: quasi-elastic scattering; short-range correlations; cold dense nuclear matter

Online: 1 December 2023 (08:00:04 CET)

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Preprint ARTICLE | doi:10.20944/preprints202312.0051.v1

Oscillation Resynchronization in a Photosensitive Reaction-Diffusion System

Da Shi, YuJin Tan, Qian Zhang, Lin Ren

Subject: Chemistry And Materials Science, Physical Chemistry Keywords: active materials; resynchronization; oscillatory media; photosensitive Belousov-Zhabotinsky reaction; reaction-diffusion system

Online: 1 December 2023 (07:59:48 CET)

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Preprint ARTICLE | doi:10.20944/preprints202312.0054.v1

Endometrial CAFs Resist Effect of Antitumor Drugs In A Patient-Derived 2-Cell Hybrid Co-Culture Model

Raed Sulaiman, Jennifer C Aske, Xiaoqian Lin, Adam Dale, Kris Gaster, Luis Rojas Espaillat, David Starks, Pradip De, Nandini Dey

Subject: Medicine And Pharmacology, Oncology And Oncogenics Keywords: Ex Vivo Resistance Platform; CAF-mediated Resistance; Combinations of cytotoxic and targeted drugs

Online: 1 December 2023 (07:57:41 CET)

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Preprint ARTICLE | doi:10.20944/preprints202312.0028.v1

Enhanced Photodiodes with Coupled Organic-Inorganic Nanostructures Utilizing double Heterostructure ligands versus Single Ligand

Shaimaa Abdalbaqi

Subject: Engineering, Electrical And Electronic Engineering Keywords: heterostructure; PbS nanocrystal; coupled organic-inorganic nanostructures

Online: 1 December 2023 (07:46:38 CET)

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Preprint ARTICLE | doi:10.20944/preprints202312.0059.v1

Large Eddy Simulation of Pulsed Film Cooling with Dielectric Barrier Discharge Plasma Actuator

Shen Zhou, Beimeng Hu, Guozhan Li, Hongjun Zhang

Subject: Engineering, Aerospace Engineering Keywords: Pulsed film ; cooling; Film cooling efficiency; ; Coherent structure; large eddy simulation

Online: 1 December 2023 (07:46:26 CET)

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Preprint ARTICLE | doi:10.20944/preprints202310.1872.v2

Alena Tensor and Its Possible Applications in Quantum Field Theory and Unification Theories

Piotr Ogonowski, Piotr Skindzier

Subject: Physical Sciences, Theoretical Physics Keywords: quantum field theory; quantum mechanics; general relativity; unification of interactions

Online: 1 December 2023 (07:38:19 CET)

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Preprint ARTICLE | doi:10.20944/preprints202312.0058.v1

Assessing Recession Constant Sensitivity and Its Interaction with Data Adjustment Parameters in Continuous Hydrological Modeling in Data Scarce Basins: A Case Study Using the Xinanjiang Model

Thandar Tun Zin, Minjiao LU, Takahiro OGURA

Subject: Environmental And Earth Sciences, Water Science And Technology Keywords: XAJ model; Recession constant; Data adjustment parameter; Model performance; Sensitivity

Online: 1 December 2023 (07:38:00 CET)

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Preprint ARTICLE | doi:10.20944/preprints202311.2001.v1

Effect of Supplement on Blood Parameters and Microbiome of Dogs with Liver Disease

Fatemeh Balouei, Bruno Stefanon, Elisa Martello, David Atuahene, Misa Sandri, Giorgio Meineri

Subject: Biology And Life Sciences, Animal Science, Veterinary Science And Zoology Keywords: Gut-Liver Axis; Supplement; Dogs

Online: 1 December 2023 (07:03:06 CET)

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Preprint REVIEW | doi:10.20944/preprints202312.0056.v1

Progress on Next Generation Electrochemical Energy Storages: Status and Challenges

Natei Ermias Benti, Mesfin Diro Chaka

Subject: Physical Sciences, Condensed Matter Physics Keywords: li-ion batteries; higher energy density; metal-air batteries; renewable energy; transportation

Online: 1 December 2023 (07:02:32 CET)

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Preprint REVIEW | doi:10.20944/preprints202312.0050.v1

Replication Protein A, the Main Eukaryotic Single-Stranded DNA Binding Protein, a Focal Point in Cellular DNA Metabolism

Heinz P. Nasheuer, Anna Marie Meaney, Timothy Hulshoff, Ines Thiele, Nichodemus O. Onwubiko

Subject: Biology And Life Sciences, Biochemistry And Molecular Biology Keywords: DNA Replication; DNA repair; homologous recombination; DNA damage signalling; replication protein A, DNA binding; protein interactions

Online: 1 December 2023 (05:44:23 CET)

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Preprint ARTICLE | doi:10.20944/preprints202312.0047.v1

Nanostructured Copper Selenide Coatings for Antifouling Applications

Sergio Mancillas-Salas, José Ángel Ledón-Smith, Marissa Pérez-Álvarez, Gregorio Cadenas-Pliego, José Manuel Mata-Padilla, Marlene Andrade-Guel, Sandra Cecilia Esparza-González, Gregorio Vargas-Gutiérrez, Uriel Alejandro Sierra-Gómez, Esmeralda Monserrat Saucedo-Salazar

Subject: Chemistry And Materials Science, Surfaces, Coatings And Films Keywords: antimicrobial activity; nanoparticles synthesis; copper selenide

Online: 1 December 2023 (05:42:27 CET)

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Preprint ARTICLE | doi:10.20944/preprints202312.0044.v1

Identification, Expression and Antimicrobial Functional Analysis of Interleukin-8 (IL-8) in Response to Streptococcus iniae and Flavobacterium Covae in Asian Seabass (Lates calcarifer Bloch, 1790)

Chayanee Muangrerk, Anurak Bunnoy, Prapansak Srisapoome

Subject: Biology And Life Sciences, Animal Science, Veterinary Science And Zoology Keywords: proinflammatory cytokine; interleukin-8; asian seabass; Streptococcus iniae; Flavobacterium covae; antimicrobial activity

Online: 1 December 2023 (05:39:33 CET)

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Preprint ARTICLE | doi:10.20944/preprints202312.0053.v1

Machine Learning Driven Dashboard for Chronic Myeloid Leukemia Prediction using Protein Sequences

Waqar Ahmad, Mudasar Iqbal, Muhammad Awais Amin, Waqas Haider Bangyal, Abdul Raheem Shahzad

Subject: Computer Science And Mathematics, Artificial Intelligence And Machine Learning Keywords: Protein Sequences; Pseudo-AAC; AAC; Dipeptide-C; Machine Learning Classifiers; Chronic Myeloid Leukemia; Blood Cancer

Online: 1 December 2023 (05:39:10 CET)

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Preprint ARTICLE | doi:10.20944/preprints202312.0042.v1

Electric State of the Surface Atmosphere in the Mountain-Steppe Landscapes of the Southern Siberia according to Meas-urement Data in the Khakass-Tyva Expedition in 2022

Konstntin Pustovalov, Petr Nagorskiy, Mariya Oglezneva, Artysh Sat, Sergei Smirnov

Subject: Environmental And Earth Sciences, Atmospheric Science And Meteorology Keywords: atmospheric electricity; Global Electric Circuit; Carnegie curve; air ions; fair-weather condition; main meteorological quantities; Siberia; mountain landscapes

Online: 1 December 2023 (05:35:00 CET)

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Preprint ARTICLE | doi:10.20944/preprints202312.0048.v1

Sa-β-Gal in Kidney Tubules as a Predictor of Renal Outcome in Patients with Chronic Kidney Disease

Pasquale Esposito, Daniela Picciotto, Daniela Verzola, Giacomo Garibotto, Emanuele Luigi Parodi, Antonella Sofia, Francesca Costigliolo, Gabriele Gaggero, Valentina Zanetti, Michela Saio, Francesca Viazzi

Subject: Medicine And Pharmacology, Urology And Nephrology Keywords: senescence; cell; chronic kidney disease; kidney tubules

Online: 1 December 2023 (05:32:39 CET)

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Preprint REVIEW | doi:10.20944/preprints202312.0039.v1

The Crayfish Plague Pathogen Aphanomyces astaci in Ireland.

Daniel J. Brady, Rossa Meade, Julian D. Reynolds, Andreas Vilcinskas, Kathrin Theissinger

Subject: Biology And Life Sciences, Aquatic Science Keywords: crayfish plague; Aphanomyces astaci; Austropotamobius pallipes; invasive species; Ireland

Online: 1 December 2023 (05:31:53 CET)

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Preprint ARTICLE | doi:10.20944/preprints202312.0029.v1

Genomics of Re-emergent Aeromonas salmonicida in Atlantic Salmon Outbreaks

Marcos Godoy, Marco Montes de Oca, Rudy Suarez, Alexis Martinez, Juan Pablo Pontigo, Diego Caro, Karina Kusch, Harry Bohle, Molly Kibenge, Frederick Kibenge, Sion Bayliss

Subject: Biology And Life Sciences, Aquatic Science Keywords: furunculosis; Aeromonas salmonicida; Salmo salar; genomic diversity

Online: 1 December 2023 (05:31:10 CET)

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Preprint ARTICLE | doi:10.20944/preprints202312.0021.v1

Development of Skin Diseases Treatment based on Exosome Derived from Plants, Humans, Medicinal Algae and Fungi

Maria Beihaghia, Reza Sahebi, Mohammad Reza Beihaghi, Homan Tehrani, Samaneh Attaran Dowom, Rahele Khosravi neissiani, Zahra Janati

Subject: Medicine And Pharmacology, Medicine And Pharmacology Keywords: Skin diseases, exosome, plants, humans, medicinal algae, fungi, treatment

Online: 1 December 2023 (05:29:59 CET)

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Annually, millions of people worldwide are affected by skin diseases, and current therapeutic approaches have limited efficacy. Advances in the treatment of exosomes have led to the development of new therapeutic methods that hold promising potential for improving the treatment options for skin diseases. The aim of this study is to produce pharmaceutical and cosmetic compounds based on exosomes for the treatment of skin conditions such as eczema, pigmentation disorders, skin sagging and aging, cellular skin regeneration, increased skin moisture, and prevention of skin shedding, among others. This study examines the effects of exosomes derived from plants, humans, medicinal algae, and fungi to treat skin diseases. Spectrophotometric analysis reveals the presence of nucleic acids and proteins in exosome samples, indicating their cargo composition. TEM micrographs demonstrate that the exosome isolation process preserves the integrity of the membrane and the crucial spherical structure for their functionality. DLS analysis confirms that isolated exosomes have a size similar to typical exosome dimensions. MTT assays indicate concentration-dependent cytotoxic effects of exosomes on skin cells, with a calculated IC50 representing a significant decrease in cell viability. Real-time PCR shows higher gene expression levels of collagen I and collagen III, indicating the potential of exosomes to enhance collagen synthesis. Tyrosinase enzyme expression analysis demonstrates the influence of exosome treatments on pathways related to melanin production. The use of exosomes derived from various sources provides a promising platform for developing new drugs in the treatment of skin diseases. Additionally, exosomes can be utilized in the treatment of autoimmune diseases and cancer, transforming them into a hopeful field of research. Plant-derived exosomes are environmentally friendly and can serve as the next generation of drug delivery systems for treating various diseases.

Preprint ARTICLE | doi:10.20944/preprints202312.0030.v1

Detection of Erosion and Progradation in the Colombian Atrato River Delta by Using Sentinel-1 Synthetic Aperture Radar Data

Rubén Darío Vásquez-Salazar, Ahmed Alejandro Cardona-Mesa, Juan Valdés-Quintero, César Anibal Olmos-Severiche, Luis Gómez, Carlos M. Travieso-González, Jean Pierre Díaz-Paz, Jorge E. Espinosa-Oviedo, Lorena Diez-Rendón, Andrés F. Garavito-González, Esteban Vásquez-Cano

Subject: Environmental And Earth Sciences, Remote Sensing Keywords: Synthetic Aperture Radar (SAR); speckle; computer vision; remote sensing; erosion; progradation; Oceanic Niñ; o Index (ONI); Gulf of Urabá; ; Atrato river

Online: 1 December 2023 (05:28:45 CET)

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Preprint REVIEW | doi:10.20944/preprints202312.0040.v1

Novel Energy-Saving Strategies in Apple Fruit Storage

Felix Büchele, Kiran Hivare, Kartik Khera, Fabio Rodrigo Thewes, Luis Carlos Argenta, Tuany Gabriela Hoffmann, Pramod V. Mahajan, Robert K. Prange, Sunil Pareek, Daniel Alexandre Neuwald

Subject: Biology And Life Sciences, Horticulture Keywords: fruit storage; energy savings; carbon footprint; 1-MCP; DCA; digital twin; SDG 12

Online: 1 December 2023 (05:17:58 CET)

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Preprint ARTICLE | doi:10.20944/preprints202312.0008.v1

Analysis of Transverse Forces for Assessment of Safety against Derailment of the Specialized Train Composition for the Transportation of Long Rails

Valeri Stoilov, Petko Sinapov, Svetoslav Slavchev, Vladislav Maznichki, Sanel Purgic

Subject: Engineering, Transportation Science And Technology Keywords: railway; derailment; safety; assessment; long rails transportation; FEM; beam element

Online: 1 December 2023 (05:17:05 CET)

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Preprint ARTICLE | doi:10.20944/preprints202311.0204.v2

Obesity is Associated with a Dysregulated Gingival Inflammatory Cytokine Response

Ahmed Khocht, Denise Bellinger, Leticia Lenoir, Crissy Irani, Gary Fraser

Subject: Medicine And Pharmacology, Dentistry And Oral Surgery Keywords: inflammatory cytokines; C-reactive protein; gingival fluid; obesity

Online: 1 December 2023 (05:16:00 CET)

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Background and Objectives: Obesity-related elevated body mass index (BMI) across life is associated with chronic low-grade inflammation and increased levels of C-reactive protein (CRP) in blood. CRP is a marker and promoter of inflammation. The objectives of this study were to examine the effect of obesity on the relationship between peripheral and gingival CRP levels and examine the effects of gingival CRP levels on gingival fluid inflammatory cytokines in periodontitis resistant obese individuals. Materials and Methods: Thirty-nine, periodontally healthy subjects were enrolled. Based on BMI scores, 20 subjects were categorized as lean and 19 as obese. A comprehensive periodontal examination was performed. Gingival crevicular fluid (GCF) and blood samples were collected. Both GCF and blood samples were assessed for interleukin-1β (IL-1β), interleukin-6 (IL-6), interleukin-8 (IL-8), tumor necrosis factor-α (TNF-α), interleukin-10 (IL-10), interleukin-17A (IL-17A) and CRP. Results: GCF CRP levels were significantly higher in obese than lean individuals. No statistically significant differences were noted between the two groups in both GCF and blood on any of the inflammatory cytokine levels. IL-17A was not detected in GCF of most subjects in both groups. GCF CRP levels were positively associated with blood CRP levels, the association tended to be stronger in obese individuals. GCF CRP showed no associations with GCF IL-10 in both groups. Although GCF CRP levels positively associated with multiple GCF inflammatory cytokines (e.g., IL-1β, IL-6, IL-8 and TNF-α) in all subjects, the associations tended to be weaker in obese individuals (e.g., IL-1β, IL-6, TNF-α). Furthermore, the levels of GCF inflammatory cytokines IL-6 and TNF-α were depressed in obese individuals. Conclusions: Obesity unfavorably influences the relationship between blood and GCF CRP levels and promotes increased CRP levels in GCF. Collectively, the findings suggest a dysregulated inflammatory cytokine response in the gingival tissues of obese individuals.

Preprint ARTICLE | doi:10.20944/preprints202312.0022.v1

Life History Traits of Aedes aegypti across Different Climatic Zones of Burkina Faso

Aboubakar Sanon, Lanjiao Wang, Abakoudjiga Arsene Moungou, Leen Delang, Athanase Badolo

Subject: Biology And Life Sciences, Insect Science Keywords: Aedes aegypti; immature stage; traits; fecundity; longevity; body size; Burkina Faso

Online: 1 December 2023 (05:15:07 CET)

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Preprint ARTICLE | doi:10.20944/preprints202312.0005.v1

Application of Microfracture Analysis to Prevent Fatigue Fractures in Materials through Non-destructive Tests

Ulises Sánchez-Santana, Gerardo Presbítero-Espinosa, José María Quiroga-Arias

Subject: Engineering, Mechanical Engineering Keywords: Microfracture; image processing; network; simulation analyzes

Online: 1 December 2023 (05:14:14 CET)

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Preprint REVIEW | doi:10.20944/preprints202312.0019.v1

A Systematic Review and Metanalysis on the Use of Hermetia illucens and Tenebrio molitor in Diets for Poultry

Yuri Katagiri Dalmoro, Carolina H. Franceschi, Catarina Stefanello

Subject: Biology And Life Sciences, Animal Science, Veterinary Science And Zoology Keywords: broiler; chitin; immune response; insect meal; insect oil; microbiota

Online: 1 December 2023 (05:11:33 CET)

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Preprint CASE REPORT | doi:10.20944/preprints202311.1685.v2

Using 3D Imaging in Preoperative Planning for Lower Third of the Face and Neck Facelift Procedures

Anastasiya S. Borisenko, Valentin I. Sharobaro, Alexey E. Avdeev, Sekina Alimova, Nigora S. Burkhonova, Anastasiya O. Fisun

Subject: Medicine And Pharmacology, Surgery Keywords: platysmaplasty; facial rejuvenation; subplatysmal structures; myotomy; neck lift; tomography

Online: 1 December 2023 (05:10:22 CET)

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Preprint ARTICLE | doi:10.20944/preprints202312.0010.v1

Structured Program for Developing Psychomotor Skills of Institutionalized Children with SEN

Rosu Daniel, Cojanu Florin, Visan Florinel Paul, Samarescu Nicoleta, Ene Mariana Augustina, Muntean Raul Ioan, Ursu Emil Vasile

Subject: Public Health And Healthcare, Physical Therapy, Sports Therapy And Rehabilitation Keywords: Psychomotor Development; Motor Skills Assessment; Institutionalized Education

Online: 1 December 2023 (05:09:15 CET)

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Preprint ARTICLE | doi:10.20944/preprints202312.0033.v1

Evolution of the Collection of Water Resources in Brazil, with Emphasis on the Watershed of the Paranaíba River Basin

Antonio Pasqualetto, Rayslla Rodrigues Quintanilha, Hellbia Samara Moreira de Carvalho Rodrigues

Subject: Environmental And Earth Sciences, Environmental Science Keywords: water; hydrographic basin; instruments; planning; management

Online: 1 December 2023 (05:08:26 CET)

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Preprint ARTICLE | doi:10.20944/preprints202312.0037.v1

Transcriptome Analysis of Stigmas of Vicia faba L. Flowers

Inés Casimiro-Soriguer, Ana M Torres

Subject: Biology And Life Sciences, Agricultural Science And Agronomy Keywords: faba bean; transcriptome; stigma; style; stigmatic cuticle; stigma receptivity

Online: 1 December 2023 (05:07:21 CET)

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Preprint ARTICLE | doi:10.20944/preprints202312.0006.v1

Transitional and/or Supernumerary Vertebra in Lumbosacrocaudal Region of the Spine – a Reality in All Domestic Mammals

Costică Toader Covașă

Subject: Medicine And Pharmacology, Veterinary Medicine Keywords: transitional vertebra; lumbosacral and sacrocaudal junctions; domestic mammals; comparing morphology

Online: 1 December 2023 (05:02:02 CET)

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Preprint ARTICLE | doi:10.20944/preprints202312.0016.v1

Assessing Electrode Characteristics in Continuous Resistance Spot Welding of BH 340 Steel Based on Dynamic Resistance

Dawei Zhao, Nikita Vdonin, Mikhail Slobodyan, Sergei Butsykin, Alexey Kiselev, Anton Gordynets

Subject: Engineering, Mechanical Engineering Keywords: resistance spot welding; electrode wear; dynamic resistance; failure process; electrode life

Online: 1 December 2023 (05:00:56 CET)

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Preprint ARTICLE | doi:10.20944/preprints202312.0003.v1

Advance Diagnostic of Respiratory Distress Syndrome in Premature Infants Treated with Surfactant and Budesonide through Computer-Assisted Chest X-ray Analysis

Tijana Prodanovic, Suzana Petrovic Savic, Nikola Prodanovic, Aleksandra Simovic, Suzana Zivojinovic, Jelena Cekovic Djordjevic, Dragana Savic

Subject: Medicine And Pharmacology, Pediatrics, Perinatology And Child Health Keywords: Respiratory Distress Syndrome; Chest X-ray; Diagnostics; Image Segmentation; Performance Evaluation

Online: 1 December 2023 (04:59:28 CET)

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Preprint ARTICLE | doi:10.20944/preprints202312.0009.v1

LSTM-based Virtual Load Sensor for Heavy-Duty Vehicles

Abdurrahman İşbitirici, Paolo Falcone, Laura Giarre', Wen Xu

Subject: Engineering, Automotive Engineering Keywords: Neural networks, virtual sensors, mass estimation,

Online: 1 December 2023 (04:58:35 CET)

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Preprint ARTICLE | doi:10.20944/preprints202312.0007.v1

Enhancing the Efficiency of Ice-Resistant Materials in Asphalt Road Surfaces A Comprehensive Performance Analysis

Yemao Zhang, Mulian Zheng, Xijuan Zhao

Subject: Engineering, Civil Engineering Keywords: Ice-suppressing materials; Mix design; Deicing performance; Durable performance

Online: 1 December 2023 (04:58:25 CET)

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Preprint ARTICLE | doi:10.20944/preprints202312.0002.v1

Transcriptomic Analysis of CRISPR/Cas9-Mediated TDP1-Knockout HEK293A Cells

Nadezhda S. Dyrkheeva, Alexandra L. Zakharenko, Anastasia A. Malakhova, Larisa S. Okorokova, Dmitry N. Shtokalo, Sergey P. Medvedev, Alexey A. Tupikin, Marsel R. Kabilov, Olga I. Lavrik

Subject: Biology And Life Sciences, Biochemistry And Molecular Biology Keywords: tyrosyl-DNA phosphodiesterase 1; topoisomerase 1; HEK293A; transcriptome; TDP1 knockout

Online: 1 December 2023 (04:53:45 CET)

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Preprint ARTICLE | doi:10.20944/preprints202312.0001.v1

Ni-Cu and Ni-Co-Modified Fly Ash Zeolite Catalysts for Selective Hydrodeoxygenation of Levulinic Acid to γ-Valerolactone

Margarita Popova, Momtchil Dimitrov, Silviya Boycheva, Ivan Dimitrov, Filip Ublekov, Neli Koseva, Genoveva Atanasova, Ágnes Szegedi

Subject: Chemistry And Materials Science, Materials Science And Technology Keywords: lignocellulosic biomass; levulinic acid; fly ash zeolite; γ -valerolactone; Co-Ni alloy

Online: 1 December 2023 (04:52:49 CET)

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Preprint ARTICLE | doi:10.20944/preprints202312.0034.v1

Pricing Contingent Claims in a Two-Interest Rate Multi-dimensional Jump-diffusion Model via Market Completion

Alexander Melnikov, Pouneh Mohammadi Nejad

Subject: Computer Science And Mathematics, Applied Mathematics Keywords: jump-diffusion; different interest rates; shortfall risk minimization; completion; multi-dimensional

Online: 1 December 2023 (04:09:36 CET)

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Preprint ARTICLE | doi:10.20944/preprints202312.0026.v1

Stress Resilience (Proprioceptive and Verbal Individual Differences) in Onco-Patients, Sportsmen and Controls

Liudmila Liutsko, Yulia V. Malova, Ekaterina Vinokurova, Irina Polikanova, Sergey E. Poddubnij, Ruben Muinos, Sergey Leonov, José Gutierrez-Maldonado

Subject: Public Health And Healthcare, Public Health And Health Services Keywords: proprioception; stress resilience; fine motor test; verbal stress test; onco-patients; sportsmen

Online: 1 December 2023 (04:08:30 CET)

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Preprint COMMUNICATION | doi:10.20944/preprints202312.0032.v1

Isoprenoid Biosynthesis Pathway Enzymes As Promising Drug Candidates Against Malaria Parasites: An In-Silico Investigation

Kuldeep Gupta, Gagandeep Singh Saggu

Subject: Biology And Life Sciences, Life Sciences Keywords: Malaria, Apicoplast, Plasmodium falciparum, Isoprenoid.

Online: 1 December 2023 (04:07:30 CET)

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Preprint COMMUNICATION | doi:10.20944/preprints202312.0024.v1

Sex-Ratio Distortion of Aedes aegypti (L.) in El Salvador: Implications for Urban Ecology and Biocontrol in Seasonally Dry Neotropical Biomes

Anna Maria Groat-Carmona, Maryory Andrea Velado-Cano, Ana Miriam González-Pérez, Víctor Daniel Carmona-Galindo

Subject: Biology And Life Sciences, Life Sciences Keywords: Neotropics; Northern Triangle of Central America; phenology; tropical dry forests; urban biology; vector ecology; vector-borne disease.

Online: 1 December 2023 (04:04:46 CET)

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Preprint ARTICLE | doi:10.20944/preprints202312.0027.v1

Steroid Metabolome Analysis in Dichorionic Diamniotic Twin Pregnancy

Andrej Černý, Martin Hill, Michala Vosatkova, Zdeněk Laštůvka, Antonín Pařízek

Subject: Medicine And Pharmacology, Obstetrics And Gynaecology Keywords: foetomaternal steroidome; neuroactive steroids; multiple pregnancy; pregnancy complications

Online: 1 December 2023 (03:49:15 CET)

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Preprint ARTICLE | doi:10.20944/preprints202312.0023.v1

From a Clustering of Adverse Symptoms After Colorectal Cancer Therapy to Chronic Fatigue and Low Ability to Work: A Cohort Study Analysis With 3 Months of Follow-Up

Tomislav Vlaski, Marija Slavic, Reiner Caspari, Bettine Bilsing, Harald Fischer, Hermann Brenner, Ben Schöttker

Subject: Medicine And Pharmacology, Oncology And Oncogenics Keywords: colorectal cancer; rehabilitation; fatigue; ability to work; symptom clusters

Online: 1 December 2023 (03:33:02 CET)

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Preprint ARTICLE | doi:10.20944/preprints202312.0020.v1

Influence of Recombinant Bovine Somatotropin (rbST) on the Metabolic Profile and Milk Composition of Lactating Murrah Buffalo

Marcelo Arne Feckinghaus, Mariana Guimarães de Oliveira Diogo, Vanessa Martins Storillo, Fabio Celidonio Pogliani, Bruno Moura Monteiro, Paulo Fantinato Neto, Melina Marie Yasuoka, Daniela Becker Birgel, Eduardo Harry Birgel Junior

Subject: Medicine And Pharmacology, Veterinary Medicine Keywords: bovine somatotropic hormone; rbST; metabolic parameters; milk yield

Online: 1 December 2023 (03:31:35 CET)

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The use of recombinant bovine somatotropin (rbST) leads to an increase, in variable amounts, of milk production in buffalo, but there is a lack of information on the influence of rbST on their metabolism. This study looked at the effects of a single 500 mg dose of rbST on lipid profile, liver and kidney function and physical, chemical and cellular constitution of milk in 14 buffalo over 14 days, from the 100th day of lactation, and compared them with 14 animals in a control group. From the 1st day after rbST, there was a rise in beta hydroxybutyrate (β-HBO), possibly due to the higher dry matter intake or by biotransformation of NEFA into β-HBO. Treatment did not influence blood glucose, non-esterified fatty acids (NEFA), triglycerides, cholesterol, total protein, albumin, AST, GGT, bilirubin, urea or creatinine. In 71.3% of the buffalo there was a gradual increase in milk production with maximal response in the first week that was then followed by a gradual decrease, whilst in 21.4%, the increase in production occurred between 7 and 10 days, and only 7.1% of animals did not respond. On the 3rd, 5th, 7th and 10th days after treatment, an increase was found in milk production between the two groups equal to 1.04, 1.52, 1.42 and 1.06 liters, respectively. In relative terms this means an increase in milk production, respectively, of 15.1%; 21.0%; 19.8 % and 15.1 %. The constitution of the milk showed no difference in the amounts of fat, lactose, total solids or somatic cell count; however, on the 3rd day after rbST, there was a decrease in protein; notably, from the 5th day, protein values show no statistical difference. It can be concluded that the application of rbST in buffalo from the 100th day of lactation is metabolically safe, since the treatment neither caused imbalances in fat metabolism nor overloaded the liver or renal function, and the changes in milk composition were transient and limited to a decrease in milk protein.

Preprint ARTICLE | doi:10.20944/preprints202312.0017.v1

Impacts of Large Dams in the Nan River Basin on the Streamflow and Sediment Supply into the Chao Phraya River, Thailand

Matharit Namsai, Butsawan Bidorn, Ruetaitip Mama, Warit Charoenlerkthawin

Subject: Engineering, Civil Engineering Keywords: runoff; environmental impact of dams; sediment transport; hydrological regime; environmental change

Online: 1 December 2023 (03:30:39 CET)

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Preprint ARTICLE | doi:10.20944/preprints202312.0018.v1

Deciphering Preferences of Shelter Volume and Distribution by Coral Reef Fishes, Using Systematic and Functional Grouping

Tamar Shabi, Yaron Ziv, Reuven Yosef, Nadav Shashar

Subject: Biology And Life Sciences, Ecology, Evolution, Behavior And Systematics Keywords: artificial reefs; restoration; shelter characteristic; red sea; shelter design

Online: 1 December 2023 (03:29:29 CET)

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Preprint ARTICLE | doi:10.20944/preprints202312.0015.v1

Micropigmentation of the Nipple-Areola Complex in Unilateral or Bilateral Mastectomised Patients

María Isabel Tovar-Gálvez, Laura Gomez Muñoz, Silvia Pinedo Extremera, Juan Carlos Sánchez-García, Ana Eugenia Marín-Jiménez, Jonathan Cortés-Martín, Raquel Rodríguez-Blanque

Subject: Public Health And Healthcare, Nursing Keywords: breast cancer; mastectomy; micropigmentation; nipple-areola complex; tattooing

Online: 1 December 2023 (03:14:52 CET)

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Preprint ARTICLE | doi:10.20944/preprints202312.0013.v1

On the Asymptotic of Solutions of Odd Order Two-Term Differential Equations

Yaudat T. Sultanaev, Nur F. Valeev, Elvira A. Nazirova

Subject: Computer Science And Mathematics, Mathematics Keywords: asymptotic methods; oscillating coefficients; singular differential equations; Campbell’ s identity

Online: 1 December 2023 (03:14:02 CET)

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Preprint REVIEW | doi:10.20944/preprints202312.0014.v1

Breast Cancer in the Tissue of the Contralateral Breast Reduction

Zoë M.A. Kuijlaars, Nadine S Hillberg, Loes Kooreman, Carmen A.H. Severens–Rijvers, Shan Shan Qiu

Subject: Medicine And Pharmacology, Oncology And Oncogenics Keywords: breast cancer; breast reduction; contralateral breast cancer

Online: 1 December 2023 (03:13:14 CET)

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Preprint ARTICLE | doi:10.20944/preprints202311.1987.v1

The Multiple Roles of Temporal Collinearity in Hox Gene Clustering for Vertebrates, Invertebrates, Complete and Split Hox Clusters

Spyros Papageorgiou

Subject: Biology And Life Sciences, Cell And Developmental Biology Keywords: Hox gene collinearity; temporal collinearity; Noether Theory; self similarity; double strand break; split Hox clusters; chicken limb growth
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Online: 1 December 2023 (03:12:17 CET)

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Preprint ARTICLE | doi:10.20944/preprints202311.1980.v1

Analysis of Characteristic Microorganisms Inside Household Washing Machines From Shanghai, China

Tong Chen, Shu Zhang, Juan Yang, Youran Li, Eiichi Kogure, Ye Zhu, Weiqi Xiong, Enhui Chen, Guiyang Shi

Subject: Public Health And Healthcare, Public, Environmental And Occupational Health Keywords: household washing machines; microbial contamination; metagenomics; pathogenic bacteria; biofilm

Online: 1 December 2023 (03:11:19 CET)

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