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Preprint ARTICLE | doi:10.20944/preprints202310.0170.v1

Quantitative Electroencephalography Markers for Accurate Diagnosis of Frontotemporal Dementia: A Spectral Power Ratio Approach

Jinwon Chang, Chul Chang

Subject: Neuroscience And Neurology, Medicine And Pharmacology Keywords: electroencephalography; power ratio; frontal lobe; temporal lobe; dementia

Online: 3 October 2023 (16:21:33 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202310.0172.v1

AI evaluates how humans connect to the built environment: two experiments in biophilia

Tobias M. Ramm, Mathias Werwie, Tim Otto, Peter A Gloor, Nikos A. Salingaros

Subject: Geography, Planning And Development, Social Sciences Keywords: Biophilic Design; Well-being and Health; Built Environment; Facial Emotion Recognition (FER); Residual Masking Networks; Large Language Models for Sentiment Detection; Architectural Impact on Emotions; Natural Elements and Productivity

Online: 3 October 2023 (16:19:34 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202310.0161.v1

Comparison of Fundamental Movement Skills and Physical Fitness in Hispanic and Non-Hispanic White Elementary School Children

Hector Morales, Moises Velasquez, Samira Negrete, Louise A Kelly

Subject: Public Health And Health Services, Public Health And Healthcare Keywords: Physical activity; fitness; Fundamental Movement Skills; Hispanic; Non-Hispanic White

Online: 3 October 2023 (15:27:06 CEST)

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Preprint REVIEW | doi:10.20944/preprints202310.0168.v1

Targeting Interleukin-17 as Novel Treatment Option for Fibrotic Diseases

Margherita Sisto, Sabrina Lisi

Subject: Immunology And Microbiology, Biology And Life Sciences Keywords: IL-17; fibrosis; autoimmune; epigenetics; biological drugs.

Online: 3 October 2023 (15:25:03 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202310.0166.v1

Polarimetric SAR Image Classification Based on Double-Channel Convolution Network and Edge-preserving Markov Random Field

Junfei Shi, Mengmeng Nie, Shanshan Ji, Cheng Shi, Hongying Liu, Haiyan Jin

Subject: Remote Sensing, Environmental And Earth Sciences Keywords: PolSAR image classification; Wishart-based complex matrix network; multi-feature network; Double-channel convolution network; Edge-preserving MRF

Online: 3 October 2023 (15:23:55 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202310.0155.v1

Comparison of Failure Loads of Polycrystalline Ceramics with Different Amount of Yttria, Glass-Ceramic, Polymers in Two Different Test Setups

Tariq F. F Alghazzawi

Subject: Dentistry And Oral Surgery, Medicine And Pharmacology Keywords: Zirconia, Glass-Ceramic; Crown; Failure Load; Yttria Concentration.

Online: 3 October 2023 (14:36:51 CEST)

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Preprint COMMUNICATION | doi:10.20944/preprints202310.0159.v1

Controlled Creation of Contact Cracks in Additive Manufactured Components

Daniel Preston, Ahmed Ashour, Julian Wright, James Watts, Daniel Rodriguez Sanmartin, Jacques Wood

Subject: Other, Engineering Keywords: Non-destructive testing; Cracks; Contact Cracks; Resonance; Flaw Seeding; Nonlinear; Nonlinear Resonance; Reference Samples

Online: 3 October 2023 (14:23:42 CEST)

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Preprint COMMUNICATION | doi:10.20944/preprints202310.0157.v1

Investigating Gender-Specific Discourse about Online Learning during COVID-19 on Twitter using Sentiment Analysis, Subjectivity Analysis, and Toxicity Analysis

Nirmalya Thakur, Shuqi Cui, Karam Khanna, Victoria Knieling, Yuvraj Nihal Duggal, Mingchen Shao

Subject: Public Health And Health Services, Public Health And Healthcare Keywords: online learning; COVID-19; Twitter; Data Analysis; Natural Language Processing; Sentiment Analysis; Subjectivity Analysis; Toxicity Analysis; Diversity Analysis

Online: 3 October 2023 (12:59:21 CEST)

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The work presented in this paper presents several novel findings from a comprehensive analysis of about 50,000 Tweets about online learning during COVID-19, posted on Twitter between November 9, 2021, and July 13, 2022. First, the results of sentiment analysis from VADER, Afinn, and TextBlob show that a higher percentage of these tweets were positive. The results of gender-specific sentiment analysis indicate that for positive tweets, negative tweets, and neutral tweets, between males and females, males posted a higher percentage of the tweets. Second, the results from subjectivity analysis show that the percentage of least opinionated, neutral opinionated, and highly opinionated tweets were 56.568%, 30.898%, and 12.534%, respectively. The gender-specific results for subjectivity analysis indicate that for each subjectivity class, males posted a higher percentage of tweets as compared to females. Third, toxicity detection was performed on the tweets to detect different categories of toxic content - toxicity, obscene, identity attack, insult, threat, and sexually explicit. The gender-specific analysis of the percentage of tweets posted by each gender in each of these categories revealed several novel insights. For instance, for the sexually explicit category, females posted a higher percentage of tweets as compared to males. Fourth, gender-specific tweeting patterns for each of these categories of toxic content were analyzed to understand the trends of the same. The results unraveled multiple paradigms of tweeting behavior, for instance, the intensity of obscene content in tweets about online learning by males and females has decreased since May 2022. Fifth, the average activity of males and females per month was calculated. The findings indicate that the average activity of females has been higher in all months as compared to males other than March 2022. Finally, country-specific tweeting patterns of males and females were also performed which presented multiple novel insights, for instance, in India a higher percentage of the tweets about online learning during COVID-19 were posted by males as compared to females.

Preprint ARTICLE | doi:10.20944/preprints202310.0153.v1

Cosmic Speed beyond Light: Gravitational and Cosmic Redshift

Soumendra Nath Thakur, Deep Bhattacharjee

Subject: Astronomy And Astrophysics, Physical Sciences Keywords: gravitational redshift; cosmic redshift; effective redshift; zero gravity sphere; cosmic expansion

Online: 3 October 2023 (11:59:49 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202310.0154.v1

A Lattice-Hinge Design-Based Stretchable Textile Microstrip Patch Antenna for Wireless Strain Sensing at 2.45GHz

Abdul Wahab Memon, Benny Malengier, Patrick Van Torre, Lieva Van Langenhove

Subject: Other, Engineering Keywords: Wearable textile antenna; multifunctional antenna; lattice hinge design; e-textile; polydimethylsiloxane; stretchable antenna; strain sensor

Online: 3 October 2023 (11:57:12 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202212.0045.v16

The Imaginary Universe (The Fine-Structure Constant is Constant, and There are Two of Them)

Szymon Łukaszyk

Subject: Mathematical Physics, Physical Sciences Keywords: emergent dimensionality; imaginary dimensions; natural units; fine-structure constant; black holes; neutron stars; white dwarfs; patternless binary messages; complex energy; complex force; Hawking radiation; extended periodic table; general relativity; photon sphere; entropic gravity; gravitational observations; holographic principle; mathematical physics

Online: 3 October 2023 (11:53:49 CEST)

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Maxwell's equations in vacuum provide the negative speed of light -c, which leads to imaginary Planck units. However, the second, negative fine-structure constant $\alpha_2^{-1} \approx -140.178$, present in the Fresnel coefficients for the normal incidence of electromagnetic radiation on monolayer graphene, establishes the different, negative speed of light in vacuum $c_2 \approx -3.06 \times 10^8~\text{[m/s]}$, which introduces imaginary Planck units different in magnitude from those parametrized with $c$. Furthermore, algebraic relations between the fine-structure constant hint that the fine-structure constant does not vary over time. It follows that electric charges are the same in real and imaginary dimensions. We model neutron stars and white dwarfs, emitting perfect black-body radiation, as \textit{objects} having energy exceeding their mass-energy equivalence ratios. We define complex energies in terms of real and imaginary natural units. Their imaginary parts, inaccessible for direct observation, store the excess of these energies. It is conjectured that the maximum atomic number $Z=238$. A black-body \textit{object} is in the equilibrium of complex energies if its radius $R_\text{eq} \approx 1.3833~R_{\text{BH}}$, which is close to the photon sphere radius $R_{\text{ps}}=1.5~R_{\text{BH}}$, and marginally greater than a locally negative energy density bound of $4/3~R_{\text{BH}}$. The complex force between real masses and imaginary charges leads to the black-body object's surface gravity and generalized Hawking radiation temperature, which includes its charge. Furthermore, this force agrees with the physical parameters of the hydrogen atom. The proposed model takes into account the value(s) of the fine-structure constant(s), which is/are otherwise neglected in general relativity, and explains the registered (GWOSC) high masses of neutron stars' mergers and the associated fast radio bursts (CHIME) without resorting to any hypothetical types of exotic stellar \textit{objects}.

Preprint ARTICLE | doi:10.20944/preprints202310.0072.v1

Better Estimate of Four Moments Theorems and Its Application to Polynomials

Yoon Tae Kim, Hyun Suk Park

Subject: Probability And Statistics, Computer Science And Mathematics Keywords: Markov diffusioin generator; carré du champ operator; Pearson distribution; Fourth moment theorem; Malliavin calculus; Jacobi generator; Romanovski-Routh generator

Online: 3 October 2023 (11:49:09 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202310.0043.v1

Unraveling the Fabric of Trust: Ethnic and Religious Dynamics in Nigeria

Yaakov Bayer

Subject: Sociology, Social Sciences Keywords: trust; ethnic affiliation; religious affiliation

Online: 3 October 2023 (11:42:42 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202310.0152.v1

Promotive and Risk Psychological Factors of Intention to Vaccinate in Health-Care Providers, Parents, and Laypeople: To Be Safe Is to Trust?

Kaja Damnjanović, Sandra Ilić, Marija Kušić, Milica Lazić, Dragoslav Popovic

Subject: Psychology, Social Sciences Keywords: vaccination intention; health-care providers; parents; lay people; promotive factors; protective factors; risk factors; vulnerability factors; vaccine decision-making; vaccination behavior

Online: 3 October 2023 (11:42:36 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202310.0146.v1

The Impact of Moderate Alcohol Consumption Combined with Physical Activity on Post-Acute Myocardial Infarction Survival and Recovery

Marius Rus, Adriana Ioana Ardelean, Simina Crisan, Constantin Tudor Luca, Paula Marian, Oana Lilliana Pobirci, Decebal Dumitru Pobirci, Veronica Huplea, Alina Stanca Osiceanu, Adrian Gheorghe Osiceanu, Claudia Elena Staniș, Felicia Liana Andronie-Cioara

Subject: Cardiac And Cardiovascular Systems, Medicine And Pharmacology Keywords: moderate alcohol consumption; physical activity; HDL-cholesterol; exercise tolerance; atherosclerotic plaques; quality of life; cardiovascular health

Online: 3 October 2023 (11:16:52 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202310.0106.v1

Cryptography Romance and War

Petar Radanliev

Subject: Philosophy, Arts And Humanities Keywords: Cryptography, Romance, War, Secure Communication, Encryption, Decryption, Historical Significance, Cultural Interpretations, Metaphorical Representations, Alice and Bob, Encoded Messages, Confidentiality, Intimacy, Adversaries, Cultural Diversity, Cryptographic Protocols, Forbidden Love, Literary Motif, Human Relationships, Privacy, Intrusion, Secure Connection

Online: 3 October 2023 (11:14:57 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202310.0151.v1

Comparative Physiological and Transcriptome Analysis of Crossostephium chinense Reveals Its Molecular Mechanisms of Salt Tolerance

Yuxin Wang, Miao Liu, Ziyu Guo, Yilin Liang, Yufan Lu, Yuxian Xu, Ming Sun

Subject: Horticulture, Biology And Life Sciences Keywords: salt stress; Crossostephium chinense; ABA signaling transduction; molecular mechanism

Online: 3 October 2023 (11:13:36 CEST)

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Preprint REVIEW | doi:10.20944/preprints202310.0145.v1

Omega-3 Lipid Mediators: Modulation of the M1/M2 Macrophage Phenotype and its Protective Role in Chronic Liver Diseases

Luis A Videla, Rodrigo Valenzuela, Andrea Del Campo, Jessica Zuñiga-Hernandez

Subject: Immunology And Allergy, Medicine And Pharmacology Keywords: chronic liver disease; specialized pro-resolving mediators; inflammation; macrophage polarization; inmunometabolism

Online: 3 October 2023 (11:11:29 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202310.0147.v1

Data Mining Suggests that CXCL14 Gene Silencing in Colon Cancer is Due to Promoter Methylation

Yanjing Wang, Siyi Wang, Yuchen Niu, Buyong Ma, Jingjing Li

Subject: Oncology And Oncogenics, Medicine And Pharmacology Keywords: colorectal cancer; CXCL14; gene silence; metastasis; DNA methylation

Online: 3 October 2023 (11:09:47 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202310.0150.v1

Novel Approach for Obtaining VNAR with Different Physicochemical Properties from Japanese Topeshark (Hemitriakis japanica)

Tomofumi Nakada-Masuta, Hiroyuki Takeda, Kazuhisa Uchida

Subject: Biochemistry And Molecular Biology, Biology And Life Sciences Keywords: Japanese topeshark; VNAR; phage display; NGS; selection pressures

Online: 3 October 2023 (10:58:56 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202310.0142.v1

Chemical Composition and Insulin-Resistance Activity of Arginine-Loaded American Cranberry (Vaccinium macrocarpon Aiton) Leaves Extracts

Oleh Koshovyi, Inna Vlasova, Heleriin Laur, Ganna Kravchenko, Oksana Krasilnikova, Sebastian Granica, Jakub P. Piwowarski, Jyrki Heinämäki, Ain Raal

Subject: Pharmacy, Medicine And Pharmacology Keywords: American cranberry; Vaccinium macrocarpon; leaf extract; chemical composition; L-arginine; insulin resistance effect; 3D printing

Online: 3 October 2023 (10:57:18 CEST)

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Preprint REVIEW | doi:10.20944/preprints202310.0148.v1

Beyond MOG and AQP4 Antibodies: Alternative Causes of Optic Neuritis

Giacomo Greco, Elena Colombo, Matteo Gastaldi, Lara Ahmad, Eleonora Tavazzi, Roberto Bergamaschi, Eleonora Rigonii

Subject: Neuroscience And Neurology, Medicine And Pharmacology Keywords: neuro-ophthalmology; optic neuritis; visual loss; AQP4; MOG; GFAP; CRION; sarcoidosis; optic perineuritis

Online: 3 October 2023 (10:52:57 CEST)

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Preprint COMMUNICATION | doi:10.20944/preprints202310.0122.v1

Analysis of the E-region Low-Altitude Quasi-Periodic Event in Low-Latitudes of China

Lei Qiao, Gang Chen, Mingkun Su, Chunxiao Yan, Erxiao Liu, Jun Wu

Subject: Space And Planetary Science, Environmental And Earth Sciences Keywords: low-latitude ionosphere; LQP echoes; plasma instability

Online: 3 October 2023 (10:50:47 CEST)

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Preprint INTERESTING IMAGES | doi:10.20944/preprints202310.0125.v1

Individual Keratinocyte Necrosis in the Epidermis Includes Apoptosis in the Skin: A Case Report.

Mitsuhiro Tachibana, Hideki Hamayasu, Kazuki Tomita, Yuta Kage

Subject: Dermatology, Medicine And Pharmacology Keywords: keratinocyte necrosis; apoptosis; cleaved caspase-3; skin

Online: 3 October 2023 (10:49:24 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202309.1002.v3

Dark Energy and Dark Matter from Extra Dimensional Symmetry as Different Manifestations of Vacuum Energy

Kabir Umar

Subject: Astronomy And Astrophysics, Physical Sciences Keywords: dark energy; dark matter; extra dimension; gravity; neutrino; vacuum energy

Online: 3 October 2023 (10:47:48 CEST)

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Preprint REVIEW | doi:10.20944/preprints202310.0118.v1

Insights from a Comprehensive Case Series Analysis: Exploring Individualized Approaches to Managing Vancouver B Periprosthetic Femoral Fractures

Adrian Cursaru, Mihnea Ioan-Gabriel Popa, Bogdan Cretu, Georgian Iacobescu, Razvan Spiridonica, Angel Rascu, Sergiu Iordache, Bogdan Serban, Cătălin Cîrstoiu

Subject: Orthopedics And Sports Medicine, Medicine And Pharmacology Keywords: keyword 1: periprosthetic femoral fractures; Vancouver classification; keyword 3: Open reduction and internal fixation; keyword 4: revision arthroplasty; keyword 5: risk factors

Online: 3 October 2023 (10:46:13 CEST)

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Preprint REVIEW | doi:10.20944/preprints202310.0123.v1

Iron Oxide Nanoparticles: Green Synthesis and Their Antimicrobial Activity

Johana Zúñiga-Miranda, Julio Guerra, Alexander Mueller, Arianna Mayorga-Ramos, Saskya E. Carrera-Pacheco, Carlos Barba-Ostria, Jorge Heredia-Moya, Linda P. Guamán

Subject: Biology And Biotechnology, Biology And Life Sciences Keywords: antimicrobial resistance; green synthesis; IONPs; antibacterial activity; antifungal activity; antiparasitic; antiviral activity

Online: 3 October 2023 (10:43:18 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202310.0149.v1

Methyl Jasmonate Application Improves Photosynthetic Performance in Blueberry Plants under Water Deficit

Elizabeth Ulloa-Inostroza, Carolin Córdova, Marco Campos, Marjorie Reyes-Díaz

Subject: Horticulture, Biology And Life Sciences Keywords: abiotic stress; antioxidant system; drought; jasmonates; photosynthesis

Online: 3 October 2023 (10:41:41 CEST)

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The plant water status is crucial for growth and production, but the current climate change scenario makes it challenging to match the water plant demand. Blueberry is an economically important crop and plays an acknowledged role in human health due to its antioxidant compounds. This research aimed to determine whether exogenous methyl jasmonate application improves the antioxidant defense mechanisms for protecting the photosynthetic performance in blueberry plants under the stress condition of water deficit. A greenhouse experiment was carried out under a 16-h light period; 20ºC; and 60-80% relative humidity for 2 weeks before treatment application of methyl jasmonate (MeJA) to blueberry plants (Vaccinium corymbosum, Brigitta cultivar). The following treatments were maintained for 7-days: (i) 80% field capacity (NoWD); (ii) 80% field capacity plus MeJA application (NoWD + MeJA); (iii) 20% field capacity (WD); and (iv) 20% field capacity plus MeJA application (WD + MeJA). The MeJA was sprayed as an aqueous solution of 10 µM MeJA (Sigma-Aldrich) over the plant's foliar system. At the end of the assay; blueberry leaves were analyzed for the relative water content; specific leaf area; lipid peroxidation; total antioxidant activity; total phenols; total anthocyanins; anthocyanidin compounds and photosynthetic performance. Brigitta cultivar showed a significant decrease in the oxidative stress at leaf levels; with an increase in antioxidant activity; phenolic compounds; total anthocyanins; delphinidin; petunidin; antheraxanthin; zeaxanthin; and an improvement in photosynthetic performance parameters. Blueberry Brigitta cultivar was shown to be susceptible to WD decreased mainly photosynthesis. However; the MeJA application on leaves induced metabolic changes; through an increase of antioxidant strategy within the plant to counteract the negative effects of WD; protecting the photosynthetic apparatus; which allows the Brigitta cultivar to withstand the period of WD.

Preprint ARTICLE | doi:10.20944/preprints202310.0126.v1

Optimizing Mobile Vision Transformers for Land Cover Classification

Papia Rozario, Ravi Gadgil, Rahul Gomes, Junsu Lee, Paige Keller, Gabriel Sipos, Grace McDonnell, Westin Impola, Joseph Rudolph

Subject: Remote Sensing, Environmental And Earth Sciences Keywords: vision transformers; Mobile ViT; ShuffleNet; CNN; Land cover classification

Online: 3 October 2023 (10:39:42 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202310.0124.v1

The Impact of Body-Mass-Index on Functional Outcomes and Bleeding Volumes in Patients Suffering Non-Traumatic Intracerebral Haemorrhage

Stefan Wanderer, Attill Saemann, Basil Grüter, Sivani Sivanrupan, Julian Louis Muff, Donato D'Alonzo, Miriam Weiss, Angelo Tortora, Christian Musahl, Gerrit Schubert, Serge Marbacher, Lukas Andereggen

Subject: Other, Public Health And Healthcare Keywords: Body-mass-index; intracerebral haemorrhage; bleeding volume; functional outcome

Online: 3 October 2023 (10:35:39 CEST)

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The association between obesity and clinical as well as radiological outcomes in patients suffering non-traumatic intracerebral haemorrhage (ICH) remains unclear. The obesity paradox suggests a protective effect regarding in-hospital mortality. This study evaluates the impact of body mass index (BMI) on functional long-term outcome and bleeding volume in patients with non-traumatic ICH. A retrospective cohort study including all consecutive patients with spontaneous ICH treated at a tertiary referral centre between December 2017 and June 2021, aged 80 years or younger (n = 218), were included. Patients were dichotomized into overweight (OW, BMI ≥ 25 kg/m2) and normal weight (NW, BMI < 25 kg/m2). Functional outcomes were assessed by the modified Rankin scale (mRS), extended Glasgow Outcome Scale (GOS-E) and the National Institutes of Health Stroke Scale score (NIHSS) at 1, 3, 6 and 12-months follow-up. Bleeding volumes were calculated as ABC/2. Univariate and multivariate analysis were performed to assess clinical predictors of favourable outcome in the long-term. Of 218 patients (66.04 ± 15.18 years) suffering non-traumatic ICH, 115 (52.75%) were OW (29.72 ± 3.82). Female sex (p = 0.1), NIHSS (p = 0.69), cardiovascular risk factors (p = 0.55), ICH volume (p = 0.19), and presence of anticoagulation (p = 0.67) did not significantly differ between the OW and NW cohort. At discharge, functional outcome did not significantly differ between both cohorts (NW, mRS 3.92 ± 2.54 vs. OW, mRS 3.21 ± 2.43, (p = 0.28)). Multivariate analysis revealed that haemorrhage volume (p = 0.01) was the only robust risk factor to predict functional outcome after 1 year. Our data suggests that in ICH patients, neither obesity nor patient’s age are negative predictors for functional outcome in the long-term. Instead, bleeding volume is a robust risk factor predicting poor functional status after ICH. Therefore, prospective randomized trials analysing this coherence are highly warranted.

Preprint ARTICLE | doi:10.20944/preprints202310.0144.v1

Acquisition of Social Communication Skills in Children with Autism through Applied Behavior Analysis (ABA) Parental Training and Video Modeling

Daniela Bordini, Ana Cláudia Moya, Graccielle R Cunha, Cristiane Silvestre Paula, Décio Brunoni, Helena Brentani, Sheila C Caetano, Jair de Jesus Mari, Leila Bagaiolo

Subject: Neuroscience And Neurology, Medicine And Pharmacology Keywords: autism spectrum disorders; applied behavior analysis; parent training; joint attention; video modelling

Online: 3 October 2023 (10:35:14 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202310.0141.v1

Conical emission induced by the Filamentation of femtosecond vortex beams in water

Yang Liu, Yuchi Huo, Lin Zhu, Mingxing Jin, He Zhang, Suyu Li, Wei Hua

Subject: Optics And Photonics, Physical Sciences Keywords: conical emission; vortex beams; topological charge; orbital angular momentum; femtosecond filament

Online: 3 October 2023 (10:34:18 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202310.0119.v1

Alcohol Consumption Assessed by a Biomarker and Self-Reported Drinking in a Sample of Pregnant Women in the South of Europe: A Comparative Study

Isabel Corrales-Gutierrez, Diego Gomez-Baya, Fatima Leon-Larios, Rocio Medero-Canela, Emilia Marchei, Ramon Mendoza, Óscar García-Algar

Subject: Obstetrics And Gynaecology, Medicine And Pharmacology Keywords: FASD; pregnancy; alcohol consumption; Spain; biomarker

Online: 3 October 2023 (10:33:05 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202310.0128.v1

Based on Strain Modal Parameters Damage Identification of Wooden Beams

Yu Cao, Zhaobo Meng, Feifei Gao, Liwei Zhang, Xiancai Ren, Huanzhi Jiang, Rong Hu

Subject: Architecture, Building And Construction, Engineering Keywords: wooden beams; damage identification; strain modes; strain mode difference; strain mode curvature difference

Online: 3 October 2023 (10:24:19 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202310.0112.v1

Microwave Field Induced Changes in Raman Modes and Magnetic Force Images of Antiferromagnetic NiO Films

Farkhad G. Aliev, Diego Caso, Aida Serrano, Miriam Jaafar, Pilar Prieto, César González-Ruano, Akashdeep Kamra

Subject: Condensed Matter Physics, Physical Sciences Keywords: NiO; domain walls; microwave; antiferromagnet; Raman

Online: 3 October 2023 (10:15:44 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202310.0120.v1

Guided Direct Time-of-Flight Lidar using Stereo Cameras for Enhanced Laser Power Efficiency

Filip Taneski, Istvan Gyongy, Tarek Al Abbas, Robert Henderson

Subject: Electrical And Electronic Engineering, Engineering Keywords: lidar; direct time-of-flight; dToF; flash lidar; SPADs; stereo depth; 3D vision

Online: 3 October 2023 (10:13:45 CEST)

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Preprint REVIEW | doi:10.20944/preprints202310.0140.v1

Insects, Plants and Microorganisms from dry LANDS as Novel Sources of Proteins and Peptides for Human Consumption

Karen Nathiely Ramírez-Guzmán, Cristian Torres-León, David Ramiro Aguillón-Gutierrez, Jorge Alejandro Aguirre-Joya

Subject: Food Science And Technology, Biology And Life Sciences Keywords: protein sources; insects; plants; microorganisms; dry lands

Online: 3 October 2023 (09:47:44 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202310.0138.v1

Multi-Frequency Differential Absorption LIDAR (DIAL) System for Aerosol and Cloud Retrievals of CO2/H2O and CH4/H2O

Jasper R Stroud, Gerd A Wagner, David F Plusquellic

Subject: Atmospheric Science And Meteorology, Environmental And Earth Sciences Keywords: DIAL; differential absorption lidar; IPDA; integrated path differential absorption LIDAR; cloud aerosol retrievals

Online: 3 October 2023 (09:35:01 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202310.0137.v1

Research on Repeated Quantum Games with Public Goods under Strong Reciprocity

Simo Sun, Yadong Shu, Jinxiu Pi, Die Zhou

Subject: Mathematical Physics, Physical Sciences Keywords: Public goods; Repeated game; Strong reciprocity; Quantum entanglement; Pareto

Online: 3 October 2023 (09:32:35 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202310.0136.v1

Arabidopsis 3β-Hydroxysteroid Dehydrogenases/C4-Decarboxylases are Essential for the Pollen and Embryonic Development

Jiawen Pan, Weifeng Li, Binzhao Chen, Linchuan Liu, Jianjun Zhang, Jianming Li

Subject: Plant Sciences, Biology And Life Sciences Keywords: sterol biosynthesis; 3β-hydroxysteroid dehydrogenase/C4-decarboxylase, C4-demethylation; pollen development; embryogenesis

Online: 3 October 2023 (09:28:16 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202310.0129.v1

Minimally Invasive Cervical Styloidectomy in Stylohyoid Syndrome (Eagle Syndrome)

Jakub Bargiel, Michał Gontarz, Tomasz Marecik, Paweł Szczurowski, Krzysztof Gąsiorowski, Grażyna Wyszyńska-Pawelec, Jan Zapała

Subject: Surgery, Medicine And Pharmacology Keywords: Eagle Syndrome; Stylalgia; Minimally Invasive Styloidectomy; MICS; Styloidectomy; Carotid Artery Syndrome; Stylohyoid Chain; Styloid Process

Online: 3 October 2023 (09:26:43 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202310.0134.v1

Elemental Composition of Copper Films Deposited on the Surface of Metals Fe, V, and Ti at the Plasma Focus Facility

Aleksandr Eriskin, Aleksandr Kobzev, Vyacheslav Kolokoltsev, Georgy Sprygin, Pavel Silin, Valerii Nikulin, Alexei Mezrin, Elena Peregudova, Sergiy Lyubchyk, Alisa Tatarinova, Phan Luong Tuan, Le Hong Khiem, Aleksandr Doroshkevich

Subject: Materials Science And Technology, Chemistry And Materials Science Keywords: Rutherford backscattering; plasma focus; films; metals

Online: 3 October 2023 (09:22:30 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202310.0089.v1

Development of Nanoparticles-Induced Genotoxicity in vitro Using Human Airway Epithelial 2D and 3D Spheroid Culture Models

Narisa K. Bordeerat, Sirirak Hemmaphan, Kotchapawn Somprasong

Subject: Pharmacology And Toxicology, Medicine And Pharmacology Keywords: Nanoparticles; Genotoxicity; 3D spheroid

Online: 3 October 2023 (09:21:30 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202310.0090.v1

Impact of Hydrocarbon Emissions from Oil and Gas Deposits on δ13С Variability in Pine Tree Rings

Olga V. Churakova (Sidorova), Georgy Batalin, Bulat Gareev, Gazinur Mingazov, Andrey Terekhin, Denis Tishin, Dilyara Kuzina, Danis Nurgaliev

Subject: Geochemistry And Petrology, Environmental And Earth Sciences Keywords: CO2; CH4; δ13С in wood; tree-ring; Pinus sylvestris; iWUE; ci/ca; temperature; precipitation; evapotranspiration; cloud fraction; Tatarstan Republic; Russia

Online: 3 October 2023 (09:20:36 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202310.0088.v1

Motherhood, Disability, and Employment: Understanding the Workplace Experiences of Mothers of Children with Intellectual Disabilities

Badrea Al Oraini

Subject: Business And Management, Business, Economics And Management Keywords: organization and management; life-work-conflict theory; mental health; female; human resources; qualitative; child

Online: 3 October 2023 (09:18:47 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202310.0099.v1

Artificial Intelligent Image Recognition System for Preventing Wrong Side Upper Limb Surgery

Yi-Chao Wu, Chao-Yun Chang, Yu-Tse Huang, Sung-Yuan Chen, Cheng-Hsuan Chen, Hsuan-Kai Kao

Subject: Bioengineering, Engineering Keywords: Intelligent Image Recognition; Left and Right Upper Limb Dislocation Surgery; Accuracy Rate; Recall Rate; IRB

Online: 3 October 2023 (09:17:35 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202310.0092.v1

MSC Sheet Assembly Duration Correlates with Extracellular Matrix Deposition, but Not Proliferative Activity or Donor Features

Valentina Sergeevna Glazyeva, Natalya Andreevna Alexandrushkina, Peter Petrovich Nimiritsky, Maria Aleksandrovna Kulebyakina, Roman Yurievich Eremichev, Pavel Igorevich Makarevich

Subject: Cell And Developmental Biology, Biology And Life Sciences Keywords: cell sheet; tissue engineering; mesenchymal stromal cells; extracellular matrix; fibroblast activating protein; myofibroblast

Online: 3 October 2023 (09:15:33 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202310.0130.v1

Characterization of Vasoreactivity in a Semi-arboreal Snake, the Tokara Habu (Protobothrops tokarensis)

Tomoki Ootawa, Siyuan Wu, Ryoya Sekio, Henry Smith, Md. Zahorul Islam, Ha Thi Thanh Nguyen, Yasuhiro Uno, Mitsuya Shiraishi, Atsushi Miyamoto

Subject: Animal Science, Veterinary Science And Zoology, Biology And Life Sciences Keywords: acetylcholine; adrenoceptors; environment; habitat; Tokara Islands; serotonin; snake; vasoreactivity

Online: 3 October 2023 (09:14:37 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202310.0103.v1

Machine Learning Prediction of the Redox Activity of Quinones

Ilia Kichev, Lyuben Borislavov, Alia Tadjer, Radostina Stoyanova

Subject: Theoretical Chemistry, Chemistry And Materials Science Keywords: quinones; machine learning; ridge regression; decision tree; ensemble methods; density functional theory; organic electrode materials

Online: 3 October 2023 (09:14:18 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202310.0133.v1

Energy Accumulation Law of Different Forms of Coal-Rock Com-Binations

Zibo Li, Guohua Zhang, Yubo Li, Wenjun Zhou, Tao Qin, Li Zeng, Gang Liu

Subject: Mining And Mineral Processing, Engineering Keywords: Coal thickness change; Combination; Combined rock strata; Energy accumulation; Rock burst

Online: 3 October 2023 (09:05:37 CEST)

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This paper aims to investigate the coal thickness change area of the combined rock strata energy accumulation law. The method of connecting a uniaxial compression experiment with a theoret-ical analysis is used in this work. We employ a combination of coal and rock to carry out our studies. We investigate how different lithologies and ratios of coal-rock height affect the me-chanical properties of the mixture and the law governing energy accumulation. We have deter-mined the following facts: (1) The combination's peak strength and elastic modulus exceed that of coal and are inferior to that of rock but are nearer to that of coal. (2) When the coal-rock height ratios are dissimilar, the peak strength and modulus of elasticity of the combination show a negative correlation with the coal-thickness share, and the pre-peak energy accumulation and impact energy index of the combination shows a positive correlation with the coal-thickness share. (3) For the combination with the same coal-rock height ratio, the peak strength, elastic modulus, pre-peak energy accumulation, and impact energy index all increase with greater rock strength and elastic modulus. The presence of a hard rock layer affects the accumulation of pre-peak energy. ( 4 ) The stress in the surrounding rock gradually decreases as the coal thick-ness increases. In the area where coal thickness declines, the stress in surrounding rock is higher than that in the region where it thickens. The energy stored in the surrounding rock is directly proportional to the coal in the zone. Conversely, areas with thinner coal deposits exhibit a lower energy storage capacity in the surrounding rock than those with thicker coal deposits. The stress distribution of surrounding rock in coal thickness change is abnormal; substantial energy accu-mulation can swiftly initiate dynamic disasters, such as rock bursts. This study has important reference significance for preventing and controlling rock burst in coal thickness change areas.

Preprint ARTICLE | doi:10.20944/preprints202310.0085.v1

Faster Gastrointestinal Transit, Reduced Small Intestinal Smooth Muscle Tone and Dysmotility in the Nlgn3^R451C Mouse Model of Autism

Suzanne Hosie, Tanya Abo-Shaban, Kevin Mou, Gayathri Kumar Balasuriya, Mitra Mohsenipour, Mohammed Uthman Alamoudi, Rhiannon Talia Filippone, Ashley Edwin Franks, Joel Charles Bornstein, Kulmira Nurgali, Elisa L Hill-Yardin

Subject: Neuroscience And Neurology, Biology And Life Sciences Keywords: autism; gut dysfunction; gut motility; gut transit; mouse model; Neuroligin-3; video-imaging

Online: 3 October 2023 (08:57:54 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202310.0109.v1

Machine Learning Based Approach for Predicting Diabetes Employing Socio-demographic Characteristics

Md. Ashikur Rahman, Lway Faisal Abdulrazak, Md. Mamun Ali, Imran Mahmud, Kawsar Ahmed, Francis M. Bui

Subject: Artificial Intelligence And Machine Learning, Computer Science And Mathematics Keywords: Diabetes; Socio demographic characteristics; machine learning; polydipsia; sudden weight loss.

Online: 3 October 2023 (08:54:18 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202310.0065.v1

Early Fire Detection using LSTM based Instance Segmentation and IoTs for Disaster Management

Sharaf J. Malebary

Subject: Artificial Intelligence And Machine Learning, Computer Science And Mathematics Keywords: Instance Segmentation; Key-frame Extraction; Fire detection; IoTs; Disaster Management

Online: 3 October 2023 (08:52:35 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202310.0066.v1

Energy Efficient Power Allocation in Massive MIMO based on Parameterized Deep DQN

Shruti Sharma, Wonsik Yoon

Subject: Telecommunications, Engineering Keywords: Convergence; multi-agent; reinforcement learning; reward; user association

Online: 3 October 2023 (08:50:12 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202310.0105.v1

Analysis and Optimal Control Measures of a Typhoid Fever Mathematical Model for a Multiple Socio-Economic Population

Stephen Ekwueme Ekwueme, Obiora Cornelius Collins, Ifeanyi Sunday Onah

Subject: Mathematical And Computational Biology, Computer Science And Mathematics Keywords: typhoid fever; reproduction number; stability analysis; optimal control; numerical analysis

Online: 3 October 2023 (08:48:38 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202310.0097.v1

Is the validity of logistic regression models developed with a medico-administrative database inferior to models developed from clinical databases?

Alain Bernard, Jonathan Cottenet, Pierre Benoit Pages, Catherine Quantin

Subject: Epidemiology And Infectious Diseases, Medicine And Pharmacology Keywords: Model performance; medico-administrative database; clinical database; Brier score; area under the receiver operating characteristic; discrimination; calibration

Online: 3 October 2023 (08:23:00 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202310.0094.v1

Isolation and Molecular Characterization of a Novel Podo-virus BIS08P22 having a Unique Terminase Enzyme Representing a new Genus in Class Caudoviricetes

Sadia Sattar, Vincenzo Carbone, Zarrin Basharat, Nazish Bostan, Aamira Tariq, Sundus Javed, Inam Ullah, Sofia Khanum, Akasha Yaqoob, Ibrar Ahmed, Muhammad Athar Abbas, Syed Tahir Abbas Shah, Eric Altermann

Subject: Virology, Biology And Life Sciences Keywords: Podo virus; temperate phages; Short tail phages, novel phage terminase, Lederbergvirus

Online: 3 October 2023 (08:19:22 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202310.0095.v1

Obesity Effect On The Respiratory Parameters In Osas Children

Carolina Caliendo, Rossella Femiano, Giuseppina Rosaria Umano, Stefano Martina, Ludovica Nucci, Letizia Perillo, Vincenzo Grassia

Subject: Life Sciences, Biology And Life Sciences Keywords: Obstructive Sleep Apnea Syndrome (OSAS); Nocturnal Home Cardiorespiratory Polygraphy (PG); Obesity; Saturation O2 (Sa02); Pediatric Sleep Questionnaire (PSQ)

Online: 3 October 2023 (08:16:58 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202310.0132.v1

Optimal Design and Fish-Passing Performance Analysis of Fish-Friendly Axial Flow Pump

Chunxia Yang, Qianxu Zhang, Jia Guo, JiaWei Wu, Yuan Zheng, Ziwei Ren

Subject: Mechanical Engineering, Engineering Keywords: Axial flow pump; LBM; optimization design; numerical simulation; fish impact mortality

Online: 3 October 2023 (08:11:38 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202310.0110.v1

The Impact of Restricting the Air Intake in Self-Aspirated Flotation Cells at Los Pelambres Concentrator

Michel Morales Gacitúa, Miguel Maldonado Saavedra, Luis Vinnett

Subject: Mining And Mineral Processing, Engineering Keywords: Self-aspirated flotation cells; WEMCO cells; flotation banks; air restriction

Online: 3 October 2023 (07:19:53 CEST)

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This article describes the impact of restricting the air intake in industrial 250 m3 WEMCO flotation cells at Los Pelambres concentrator. The influence of this air restriction on the hydrodynamic and metallurgical performance of this type of machine was evaluated. The experiments were conducted in single flotation cells and in entire rougher banks. In all cases, the gas holdup was measured to estimate the effectiveness of the obstruction system to decrease the air concentration. In single cells, axial profiles for solid percentage and particle size were evaluated. In addition, a mass balance was conducted to assess the copper recovery and concentrate features. In individual cells, the air restriction led to a decrease in the gas holdup. However, this slight change was enough to obtain a more stable froth zone and a better solids suspension. The latter was observed as a higher P80 below the pulp-froth interface, a less diluted pulp at this level, a slightly higher Cu recovery, and a coarser concentrate product. A mineralogical analysis of the concentrate sample also showed the presence of coarser liberated Cu-sulfide particles. The results in single cells suggested an improvement in the recovery of coarse particles by a more intense solids suspension. The air intake was also restricted in 3 rougher banks to assess the impact of the air obstruction on the overall performance of the respective circuit. Eleven out of fourteen cells were operated with air restriction, which led to a significant recovery improvement of 0.9%-1.6% (absolute) with a 95% confidence level. Size-by-size mass balances were also conducted for the rougher circuits, which proved that the recovery improvements were justified by the simultaneous increase in the recovery of coarse and fine particles. Thus, a restriction of the air intake showed that the decrease in the gas holdup (and in the bubble surface area flux) was compensated by a better solids suspension and a higher turbulence in the impeller. The former promotes the recovery of coarse particles, whereas the latter improves the interaction between bubbles and fine particles. Further developments are being made to implement a regulatory control strategy to control the air intake in self-aspirated flotation cells, and to use this approach for optimizing industrial flotation banks.

Preprint ARTICLE | doi:10.20944/preprints202310.0115.v1

Alternatives to the Use of Carbon Dioxide in Two Phases for the Stunning of Broiler Chickens at Slaughter

Daniel Santiago Rucinque, Antonio Velarde, Aida Xercavins, Aranzazu Varvaró-Porter, Troy John Gibson, Virginie Michel, Alexandra Contreras-Jodar

Subject: Animal Science, Veterinary Science And Zoology, Biology And Life Sciences Keywords: controlled atmosphere stunning; gas stunning; carbon dioxide; inert gases; nitrogen; uncon-sciousness; death; aversion; broiler chicken

Online: 3 October 2023 (07:18:44 CEST)

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Preprint REVIEW | doi:10.20944/preprints202310.0116.v1

What Should We Know about Drugs Levels and Therapeutic Drug Monitoring during Pregnancy and Breastfeeding in Inflammatory Bowel Disease under Biologic Therapy?

Mathiilde Barrau, Xavier Roblin, Leslie Andromaque, Aurore Rozieres, Mathias Faure, Stephane Paul, Stephane Nancey

Subject: Gastroenterology And Hepatology, Medicine And Pharmacology Keywords: TDM; prgnancy; chilfborn; lactation; biotherapy; IBD

Online: 3 October 2023 (07:15:39 CEST)

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The real long-term influences of in utero drug exposure in pregnant women on childhood development have yet to be fully determined and depend on the duration of in utero drug exposure and maternal drug levels. Therapeutic drug monitoring (TDM) during pregnancy may help limit fetal drug exposure while maintaining therapeutic drug levels in maternal blood. Most antibody therapies used in patients with Inflammatory Bowel Disease (IBD) are IgG molecules which are actively transported across the placenta, especially during the third trimester of the pregnancy. Here we propose an up to date clinical review to summarize the available findings of serum drug levels in maternal blood during pregnancy, in the blood cord, infants at delivery and in breast milk of patients with IBD treated with biologics. Conversely to adalimumab (ADA) levels, which are relatively stable during pregnancy, infliximab (IFX) drug clearance decreased significantly during the second and third trimesters, leading to increasing maternal IFX concentrations. As most guidelines recommend using live vaccines in infants at the age of one or earlier in case of negative serum drug levels in newborns, statistical models could help clinicians in making a decision to adjust the last dose of the biologic during pregnancy and to determine the optimal date to vaccinate. Altogether, data from the literature offers strong reassurance regarding the safety profile of anti-TNFα therapies during pregnancy not only for IBD patients who intend to conceive, but also for pregnant women and for the physicians taking care of these patients. ADA and IFX levels in breast milk are detectable but very low and therefore it is recommended to pursue breast feeding under anti-TNFα therapy. Our knowledge on ustekinumab or vedolizumab levels in pregnant women remains unclear and scarce. It is currently not recommended in patients with IBD in clinical practice. Therefore, TDM and proactive dose adjustment are not necessary during pregnancy since its impact for making a clinical decision have not yet been clearly demonstrated in routine practice. Overall, drug concentrations in the blood cord, the infant at birth and postpartum serum concentrations in infants, due to active placental drug transfer, may have a greater impact than the limited drug transfer in breast milk during lactation on the risk of infection and developmental outcomes. Ustekinumab and vedolizumab exposure during pregnancy and lactation are both considered low risk by the recent ECCO guidelines despite the limited data currently available.

Preprint ARTICLE | doi:10.20944/preprints202310.0117.v1

Effect of Dietary Calcium Propionate Inclusion Level and Duration in High-Risk, Newly Received Stocker Calves: Growth Performance, Body Fat Reserves and Health

Daniel Rodriguez-Cordero, Octavio Carrillo-Muro, Pedro Hernandez-Briano, Alejandro Rivera-Villegas, Alfredo Estrada-Angulo

Subject: Food Science And Technology, Biology And Life Sciences Keywords: beef calf; gluconeogenic precursor's; reception diet; serum metabolites; hemogram

Online: 3 October 2023 (07:13:13 CEST)

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Fifty bull calves of the Continental × British crossbred (147.0 ± 1.67 kg body weight, BW) were used in a completely randomized design to investigate the effect varying levels and duration of calcium propionate (CaPr) supplementation on the growth performance, body fat reserves, serum metabolites, and hemogram of high-risk newly received stocker calves. These calves were individually housed and fed a received-diet for 56 d. The calves received the following treatments: 1) No CaPr (CTL), 2) 20 g CaPr/calf/d, 3) 40 g CaPr/calf/d, 4) 60 g CaPr/calf/d, and 5) 80 g CaPr/calf/d, during 14, 28, 42 and 56 d the after arrival. The supplementation with 20 g CaPr from 28 to 56 d after arrival increases average daily gain (ADG) and BW (p < 0.05), and DMI is not affected (p > 0.05). This is reflected at 28 d with increases (p < 0.05) in ADG:DMI ratio and longissimus muscle area (LMA), and at 56 d in back fat thickness (BFT) y fat thickness at the rump (FTR). Also, with 20 g, blood urea nitrogen decreased (p < 0.05); and increases were observed in the activity of gamma glutamyltransferase, monocytes (quadratic trend, p < 0.07) and granulocytes% (quadratic effect, p < 0.03). However, as the level of CaPr increased during the first 14 d after arrival, daily water intake, creatinine, total cholesterol, mean corpuscular hemoglobin concentration (linear effect, p < 0.05), globulin, calcium and mean corpuscular volume (linear trend, p = 0.08) increased, while alkaline phosphatase (linear trend, p = 0.07) and lymphocytes (linear effect, p = 0.05) decreased. Finally, the different levels of CaPr supplementation did not produce any significant effects or differences (p > 0.05), in the remaining serum metabolites and hemogram (p > 0.05). Ultimately, the inclusion of 20 g CaPr/calf/d in the diet for 28 d in newly received stocker calves increases ADG, ADG:DMI ratio and LMA. If extended to 42 or 56 d, the increases in ADG persist, but there is also a rise in body fat reserves (BFT and FTR) at the expense of a reduction in ADG:DMI ratio. Furthermore, the different supplementation levels did not impact the reference range for most serum metabolites or the health of stocker calves.

Preprint REVIEW | doi:10.20944/preprints202310.0121.v1

Biotechnological Applications of Microbial Pigments

João Vitor de Oliveira Barreto, Livia Marques Casanova, Athayde Neves Junior, Maria Cristina Pinheiro Pereira Reis Mansur, Alane Beatriz Vermelho

Subject: Biology And Biotechnology, Biology And Life Sciences Keywords: Microbial pigments; Biocolors; Organic pigments; Biodegradable pigments; Biotechnology

Online: 3 October 2023 (07:10:28 CEST)

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Preprint COMMUNICATION | doi:10.20944/preprints202310.0091.v1

Neutrophil to Lymphocyte Ratio as a Prognostic Marker in Amyotrophic Lateral Sclerosis

Camille Cotet, Hugo Alarcan, Olivier Herault, Philippe Corcia, Patrick Vourc'h, Christian R Andres, Hélène Blasco, Charlotte Veyrat-Durebex

Subject: Neuroscience And Neurology, Medicine And Pharmacology Keywords: Amyotrophic lateral sclerosis; neutrophils; lymphocytes; NLR; survival; prognosis

Online: 3 October 2023 (05:55:51 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202310.0079.v1

Challenges of the Pig Farming Sector

Aistė Galnaitytė, Irena Kriščiukaitienė, Virginia Namiotko, Vida Dabkienė

Subject: Economics, Business, Economics And Management Keywords: Pig Farming; Farm Size; TOPSIS

Online: 3 October 2023 (05:53:34 CEST)

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Preprint REVIEW | doi:10.20944/preprints202310.0087.v1

Circular Economy Integration in Additive Manufacturing

Hribhu Chowdhury

Subject: Industrial And Manufacturing Engineering, Engineering Keywords: sustainability; circular economy; additive manufacturing; recyclability

Online: 3 October 2023 (05:43:52 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202310.0076.v1

Exotic Particle Dynamics using Novel Hermitian Spin Matrices

Timothy Ganesan

Subject: Mathematical Physics, Physical Sciences Keywords: exotic particle dynamics; generalized hermitian spin matrices; Pauli matrices; electrodynamics; fermionic quantum Heisenberg model; bosonic spin systems

Online: 3 October 2023 (05:40:19 CEST)

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Preprint REVIEW | doi:10.20944/preprints202310.0086.v1

Main Carob Pathogens in the Mediterranean Basin: Current Knowledge and Outlook in Italy

Ivana Castello, Giancarlo Polizzi, Alessandro Vitale

Subject: Agricultural Science And Agronomy, Biology And Life Sciences Keywords: Ceratonia siliqua; powdery mildew; Cercospora leaf spot; wood decay fungi; Xylosandrus compactus-Fusarium solani.

Online: 3 October 2023 (05:37:25 CEST)

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Main pathogens affecting carob (Ceratonia siliqua) tree in the Mediterranean basin are described in this overview. The most widespread diseases periodically occurring on carob orchards are powdery mildew (Pseudoidium ceratoniae) and cercospora leaf spot (Pseudocercospora ceratoniae). The causal agents of so-called “black leaf spots” (e.g. Pestaliotiopsis, Phyllosticta and Septoria spp.) are responsible for similar symptoms to above mentioned foliar diseases but are reported on carob orchards with a negligible frequency. Likewise, canker and branch diebacks caused by fungal species belonging to Botryosphaeriaceae are almost never recorded. Among wood diseases that may compromise old or previously damaged carob specimens, “brown cubical heart rot” caused by Laetiporus sulphureus is the most widespread and recurrent issue; this pathogen is also well-known for edible fruit bodies that are also appreciated for pharmaceutical and industrial purposes. On the other hand, “white decays” caused by Fomes and Ganoderma species are less common and reported for the first time in this review. Like-gall protuberances on twigs at uncertain aetiology or tumours on branches associated to Rhyzobium radiobacter are described although these symptoms are seldom detected as it happens also for necrotic leaf spots caused by Pseudomonas syringae pv. ciccaronei. A list of worldwide pathogens not yet recorded but at high-risk potential of introduction in Italian carob producing area is also provided. Finally, some concerns are addressed to new phytopathogenic fungi vectored by invasive Xylosandrus compactus ambrosia beetle. Comprehensively, all described pathogens could potentially in near future become limiting factors for carob production, because they could be favoured by high-density orchards, increasing global network of trade exchanges and high frequency through which extreme events of climate changes globally occur. Thus, symptoms and signs, causal agents, epidemiology and whenever applicable recommendations for disease prevention and management are provided in this review.

Preprint ARTICLE | doi:10.20944/preprints202310.0078.v1

Transcriptome Analysis and Metabolic Profiling Reveal the Key Regulatory Pathways in Drought Stress Responses and Recovery in Tomato

Jinshuai Shu, Lili Zhang, Guiming Liu, Xiaoxuan Wang, Fuzhong Liu, Ying Zhang, Yuhui Chen

Subject: Agricultural Science And Agronomy, Biology And Life Sciences Keywords: transcriptomics; metabolomics; drought stress; rehydration; genes; pathway

Online: 3 October 2023 (05:34:06 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202310.0114.v1

Deep Learning-based Prediction of Stress and Strain Maps in Arterial Walls for Improved Cardiovascular Risk Assessment

Yasin Shokrollahi, Pengfei Dong, Xianqi Li, Linxia Gu

Subject: Computer Science, Computer Science And Mathematics Keywords: Finite element methods (FEM); cardiovascular disease; convolutional neural network (CNN); U-Net; conditional generative adversarial neural network (cGAN); stress-strain field maps

Online: 3 October 2023 (04:57:59 CEST)

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Conducting computational stress-strain analysis using finite element methods (FEM) is a common approach when dealing with the complex geometries of atherosclerosis, which is a leading cause of global mortality and complex cardiovascular disease. The considerable expense linked to FEM analysis encourages the substitution of FEM with a considerably faster data-driven machine learning (ML) approach. This study investigated the potential of end-to-end deep learning tools as a more effective substitute for FEM in predicting stress-strain fields within 2D cross sections of arterial wall. We first proposed a U-Net based fully convolutional neural network (CNN) to predict the von Mises stress and strain distribution based on the spatial arrangement of calcification within arterial wall cross-sections. Further, we developed a conditional generative adversarial network (cGAN) to enhance, particularly from the perceptual perspective, the prediction accuracy of stress and strain field maps for arterial walls with various calcification quantities and spatial configurations. On top of U-Net and cGAN, we also proposed their ensemble approaches to further improve the prediction accuracy of field maps. Our dataset, consisting of input and output images, was generated by implementing boundary conditions and extracting stress-strain field maps. The trained U-Net models can accurately predict von Mises stress and strain fields, with structural similarity index scores (SSIM) of 0.854 and 0.830 and mean squared errors of 0.017 and 0.018 for stress and strain, respectively, on a reserved test set. Meanwhile, the cGAN models in a combination of ensemble and transfer learning techniques demonstrate high accuracy in predicting von Mises stress and strain fields, as evidenced by SSIM scores of 0.890 for stress and 0.803 for strain. Additionally, mean squared errors of 0.008 for stress and 0.017 for strain further support the model's performance on a designated test set. Overall, this study developed a surrogate model for finite element analysis, which can accurately and efficiently predict stress-strain fields of arterial walls regardless of complex geometries and boundary conditions.

Preprint ARTICLE | doi:10.20944/preprints202310.0111.v1

Angiopoietins as Predictor Indexes in COVID COVID-19 Patients in Delta and Omicron Waves

Panagiota Tsiatsiou, Kyriakos Kouirouxis, Vasiliki Tsaireli, Antonia Lanta, Maria Papaioannou, Efthymia Protonotariou, Lemonia Skoura

Subject: Epidemiology And Infectious Diseases, Medicine And Pharmacology Keywords: Angiopoietin-1 (Ang-1); Angiopoietin-2 (Ang-2); Angiopoietin-2/Angiopoietin-1 ratio (Ang-2/Ang-1); COVID-19; endothelial dysfunction

Online: 3 October 2023 (04:46:41 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202310.0108.v1

Study and Modeling the Impact of June 2015 Geomagnetic Storms on the Brazilian Ionosphere

Oladayo O. Afolabi, C.M.N Candido, F. Becker-Guedes, C. Amory-Mazaudier

Subject: Space Science, Physical Sciences Keywords: Vertical Total Electron Content (VTEC); Prompt Penetration of Magnetospheric Convection Electric Field; Disturbance Dynamo Electric Field (DDEF); DP2; Ddyn

Online: 3 October 2023 (04:36:00 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202310.0104.v1

Dynamic and Seasonal Distribution of Enteric Viruses in Surface and Well Water in Riyadh (Saudi Arabia)

Islem Abid, Albert Blanco, Nawal Al-Otaibi, Susana Guix, Maria Isabel Costadreda, Rosa Maria Pinto, Albert Bosch

Subject: Virology, Biology And Life Sciences Keywords: Hepatitis A; Hepatitis E; Norovirus; Real-time RT-qPCR

Online: 3 October 2023 (04:25:03 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202310.0098.v1

Optimal Adaptive Continuous Barrier Function Design for Non-linear Systems Under Model Uncertainty and External Disturbance using Terminal Sliding Mode Control

Fayez F. M. El-Sousy, Saleh Mobayen, Mohammadreza Askari Sepestanaki, Mohammed H. Alqahtani, Ali S. Aljumah, Sulaiman Z. Almutairi

Subject: Control And Systems Engineering, Engineering Keywords: Nonlinear system; sliding mode control; adaptive tuning; model uncertainties; external disturbances

Online: 3 October 2023 (03:51:17 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202310.0093.v1

Impact of Financial Development Shocks on Renewable Energy Consumption in Saudi Arabia

Raga M. Elzaki

Subject: Area Studies, Social Sciences Keywords: Renewable energy; financial development; VAR; Saudi Arabia

Online: 3 October 2023 (03:50:24 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202309.2050.v1

T. vaginalis: Monolayer and cluster formation - ultrastructural aspects using HR-SEM

Sharmila Ortiz, Raphael Verdan, Fabio da Silva de Azevedo Fortes, Marlene Benchimol

Subject: Parasitology, Biology And Life Sciences Keywords: anaerobic parasites; pathogenicity; cell communication; cadherins; high-resolution SEM; Trichomonas adhesion.

Online: 3 October 2023 (03:48:46 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202309.2015.v1

Comparative analysis of COVID-19 response measures and their impact on mortality rate

Tomokazu Konishi

Subject: Health Policy And Services, Public Health And Healthcare Keywords: keyword logarithmic growth rates; lockdown; vaccination; containment of the pandemic; identifying and isolating patients

Online: 3 October 2023 (03:45:36 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202309.2021.v1

Developmental Changes and Sex Differences in Infants' Neural Sensitivity to Emotional Prosodies in Spoken Words

Chieh Kao, Yang Zhang

Subject: Psychology, Social Sciences Keywords: emotional prosody; mismatch response; sex differences; infancy

Online: 3 October 2023 (03:44:18 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202309.2045.v1

Experimental investigation of the Metasurfaced Reverberation Chamber

Hengyi Sun, Zhuo Li, Changqing Gu, Qian Xu, Yaoran Zhang, Zhengran Xu, Xiaoping Luo, Changjiang Sun, Alfred Chan

Subject: Electrical And Electronic Engineering, Engineering Keywords: Metasurface; Reverberation Chamber; Q factor; K factor; Total Scattering Cross Section

Online: 3 October 2023 (03:41:59 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202309.2057.v1

Comparison of sunshine duration measurements between the Campbell-Stokes sunshine recorder and three automatic sensors at three locations in Cyprus.

Stelios Pashiardis, Alexandros PELENGARIS, Soteris A. KALOGIROU

Subject: Atmospheric Science And Meteorology, Environmental And Earth Sciences Keywords: sunshine duration; Campbell-Stokes heliograph; pyranometer; pyrheliometer; CSD3 sensors

Online: 3 October 2023 (03:39:46 CEST)

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The purpose of this paper is to compare daily sunshine duration (SD) measured by Campbell-Stokes sunshine recorder (CS) with three automatic instruments (Kipp & Zonen pyranometers (CM6B), pyrheliometer (CHP1) and CSD3 sunshine recorders). The comparisons are essential, since in recent decades automatic sunshine duration sensors have been systematically replacing the manual measurements affecting therefore the continuity of the CS time series. The comparisons were applied to the daily SD data of three synoptic stations (Larnaca A/P, Pafos A/P and Athalassa) where parallel measurements of manual and automatic instruments are carried out during the periods 2009-2012 and 2012-2015. The CSD3 measurements were obtained from two automatic weather stations (AWS) (Mennogia and Pentakomo) which are closed to the synoptic station of Larnaca A/P. The comparisons cover the daily and monthly sums, their statistical distributions and their relationships. The daily differences of the pairs of the sunshine recorders installed at the same location are mostly within the range of -1.0 to +1.0 h. At Larnaca, in the period 2009-2012, the pyranometric method (Gl) is higher than the CS in the summer months, while during the winter months it is lower than CS. Pafos and Athalassa showed higher values of CS comparing to Gl and the pyrheliometric method (Pr), respectively, almost throughout the year. Generally, the annual average daily differences between the different pairs range between 0.3 and 0.5 h. Regression equations were determined allowing the estimation of daily SD under different sky conditions. The closest relations between different pairs were obtained in ‘clear sky’ and ‘all sky’ conditions, as it is indicated by the high coefficient of determinations. R2 reached the values of 0.92 and 0.96 under ‘all sky’ conditions, and between 0.80 and 0.91 under ‘clear’ sky conditions, respectively. An increase in cloud cover causes an increase in the SD differences recorded by the relevant devices. Comparing statistically the different pairs using the Mann-Whitney nonparametric test which is the alternative to the Two Sample T parametric test, it was found that the medians are not statistically different. However, significant differences were only detected in the case of the pair of CS and Pr at Athalassa (2012-2015) using both tests. In the rest of the cases the differences are not statistically significant at the 5% level.

Preprint REVIEW | doi:10.20944/preprints202309.2029.v1

From Health-in-all-policies to Climate-in-all-policies: using the synergies between Health Promotion and Climate Protection to Take Action

K. Viktoria Stein, Thomas Ernst Dorner

Subject: Public, Environmental And Occupational Health, Public Health And Healthcare Keywords: one health; health promotion; climate change; exercise; nutrition; health literacy; climate literacy; sustainability; social determinants

Online: 3 October 2023 (03:38:14 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202309.2078.v1

High-molecular-weight dissolved organic matter enhanced phosphorus availability in paddy soils: Evidence from field and microcosm experiments

Hai-Bo Wang, Xi-Peng Liu, Bing-Jie Jin, Yu-Chen Shu, Cheng-Liang Sun, Yong-Guan Zhu, Xian-Yong Lin

Subject: Soil Science, Environmental And Earth Sciences Keywords: Soil phosphorus availability; Dissolved organic matter; Organic fertilizer; Competitive adsorption; Molecular weight

Online: 3 October 2023 (03:36:39 CEST)

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Preprint REVIEW | doi:10.20944/preprints202309.2113.v1

Navigating the Data Architecture Landscape: A Comparative Analysis of Data Warehouse, Data Lake, Data Lakehouse, and Data Mesh

Benjamin wong

Subject: Hardware And Architecture, Computer Science And Mathematics Keywords: Data, DWH, Data Warehouse, Architecture, Data Lake, Storage, Analysis, Data Mesh, Analytical, Architectural, Data Vault

Online: 3 October 2023 (03:28:55 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202309.2081.v1

Additive manufacturing of High Entropy Alloys: Trends, challenges and future perspectives

Mainak Saha

Subject: Metallurgy And Metallurgical Engineering, Engineering Keywords: Additive manufacturing; compositionally complex alloys; microstructure-property correlation

Online: 3 October 2023 (03:25:09 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202309.2072.v1

Silicon-organic hybrid electro-optic modulator and microwave photonics signal processing applications

Zihan Zhou, Meng Chao, Xinxin Su, Shuanglin Fu, Ruonan Liu, Zhihua Li, Shuhui Bo, Zhuo Chen, Zhenlin Wu, Xiuyou Han

Subject: Optics And Photonics, Physical Sciences Keywords: Electro-optic modulator, silicon photonics, silicon-organic hybrid, Mach-Zehnder modulator, slot waveguide

Online: 3 October 2023 (03:23:17 CEST)

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Preprint REVIEW | doi:10.20944/preprints202309.2079.v1

Energy literacy: a systematic review of scientific literature

Oscar Sánchez Santillán, Karla Graciela Cedano Villavicencio

Subject: Other, Environmental And Earth Sciences Keywords: Energy literacy; energy reviews; energy-related knowledge; energy transitions; energy education.

Online: 3 October 2023 (03:21:33 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202309.2092.v1

Sensitivity Analysis of Intensity-Modulated Plastic Optical Fiber Sensors for Effective Ageing Detection in Rapeseed Transformer Oil

Ugochukwu Elele, Azam Nekahi, Arshad Arshad, Kate McAulay, Issouf Fofana

Subject: Electrical And Electronic Engineering, Engineering Keywords: Ageing; Fiber Optic Sensor; Transformer Oil; Refractive Index; Evanescent Field; Intensity Modulation

Online: 3 October 2023 (03:18:58 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202309.2080.v1

Angle Trisection With Growth Rate Of The Golden Ratio

seyed kazem mousavi

Subject: Geometry And Topology, Computer Science And Mathematics Keywords: Angle trisection; Six-dimensional time-space; Golden ratio.

Online: 3 October 2023 (03:16:54 CEST)

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Preprint HYPOTHESIS | doi:10.20944/preprints202308.0648.v2

Adoptive In Situ Vaccination with Cyclical Intermittent Stereotactic Body Radiotherapy (SBRT) and Immunotherapy – a Review and Proposed Strategy

Kumara Swamy

Subject: Oncology And Oncogenics, Medicine And Pharmacology Keywords: in-situ-vaccination, Immunotherapy, cyclical-intermittent-SBRT, vascular-normalization

Online: 3 October 2023 (03:15:10 CEST)

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Preprint REVIEW | doi:10.20944/preprints202309.2128.v1

The effect of electrolyte on the kinetics of hydrogen evolution reaction

Goitom K. Gebremariam, Aleksandar Z. Jovanović, Igor A Pašti

Subject: Electrochemistry, Chemistry And Materials Science Keywords: Hydrogen evolution reaction, kinetics; electrolyte; electrolyte ions; electrolyte impurities; electrolyte engineering

Online: 3 October 2023 (03:13:04 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202309.1274.v2

Nanofiber-Based Gas Diffusion Layer for Improve Performance in Air-Cathode Microbial Fuel Cells

Giulia Massaglia, Tommaso Serra, Candido Fabrizio Pirri, Marzia Quaglio

Subject: Energy And Fuel Technology, Engineering Keywords: Electrospinning; Fuel Cell; Laser-induced nanomaterials; Microbial Fuel Cells; Gas Diffusion Layer; ; Triple phase boundary; Oxygen Reduction Reaction

Online: 3 October 2023 (03:12:07 CEST)

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Preprint COMMUNICATION | doi:10.20944/preprints202309.2141.v1

2-aminoindane-2-phosphonic acid (AIP) improves Cannabis sativa protoplast isolation and early cellular division

Adrian S Monthony, Andrew Maxwell Phineas Jones

Subject: Plant Sciences, Biology And Life Sciences Keywords: protoplast, Cannabis sativa, regeneration, AIP, phenylpropanoid, tissue culture

Online: 3 October 2023 (03:11:20 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202310.0058.v1

A comparison of Nursing Activity Score means for missed care dimensions in intensive care unit patients

Nasrin Hanifi

Subject: Other, Medicine And Pharmacology Keywords: Care left undone, health services misuses, medical errors of omission, missed nursing care, workload.

Online: 3 October 2023 (03:10:26 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202310.0084.v1

Synthesis and Characterization of Bioactive Glass and Zinc Oxide Nanoparticles with Enamel Remineralization and Antibacterial Capabilities

Ryota Nagasaki, Keiji Nagano, Takasi Nezu, Masahiro Iijima

Subject: Biomaterials, Chemistry And Materials Science Keywords: bioactive glass; zinc oxide; nanoparticle; enamel remineralization; antibacterial property

Online: 3 October 2023 (03:09:36 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202310.0073.v1

Deep learning as a tool of quantum error reduction in quantum image processing

Krzysztof Werner, Kamil Wereszczyński, Rafał Potempa, Krzysztof A Cyran

Subject: Artificial Intelligence And Machine Learning, Computer Science And Mathematics Keywords: quantum computing; quantum error correction; quantum sampling; quantum information theory; GAN; pix2pix; LPIQE; PDU

Online: 3 October 2023 (03:09:23 CEST)

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Preprint DATA DESCRIPTOR | doi:10.20944/preprints202310.0082.v1

Precision Metagenomic Next-Generation Sequencing Data of Respiratory Infection

Sadia Almas, Rob E Carpenter, Vaibhav Kumar Tamrakar, Anuradha Singh, Aditya Sharma, Rahul Sharma

Subject: Public Health And Health Services, Public Health And Healthcare Keywords: Precision Metagenomics; Next Generation Sequencing (NGS), Respiratory infections, Microbiome, Targeted Sequencing

Online: 3 October 2023 (03:06:42 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202310.0080.v1

Prescription Practices of Cannabinoids in Children with Cere-bral Palsy Worldwide - A Survey of the Swiss Cerebral Palsy Registry

Sandra Hunziker, Federico Morosoli, Kathrin Zuercher, Anne Tscherter, Sebastian Grunt

Subject: Neuroscience And Neurology, Medicine And Pharmacology Keywords: cannabis; cannabinoids; tetrahydrocannabinol; cannabidiol; cerebral palsy; pediatrics

Online: 3 October 2023 (02:58:34 CEST)

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Preprint REVIEW | doi:10.20944/preprints202309.1965.v1

Advances in 3D Printing Technology: An Overview

Min Jeong, Kyle Radomski, Diana Lopez, Jack T. Liu, Jason D Lee, Sang J. Lee

Subject: Dentistry And Oral Surgery, Medicine And Pharmacology Keywords: 3D printing; digital light processing; stereolithography; digital dentistry; dental material

Online: 3 October 2023 (02:56:01 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202309.2011.v1

Optimal wind farm sites-selection using Geographic Information System based mathematical modelling and fuzzy logic tools: A case study of Burundi

GATOTO Placide, Michel Roddy Lollchund

Subject: Other, Physical Sciences Keywords: Burundi; Wind farm site selection; multi-criteria decision-making (MCDM); Fuzzy AHP logic tool; GIS

Online: 3 October 2023 (02:53:57 CEST)

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