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Pumice as a Novel Nature Heterogeneous Catalyst for Synthesis of 3,4-dihydropyrimidine-2-(1H)-Ones/Thiones via Biginelli Reaction under Solvent-free Conditions
Version 1
: Received: 30 April 2021 / Approved: 20 May 2021 / Online: 20 May 2021 (13:38:53 CEST)
How to cite:
Al-Wahaibi, L.H.; Abdelhamid, A.A.; Saber, S.A.; Elkanzi, N.A.; Ali, A.M. Pumice as a Novel Nature Heterogeneous Catalyst for Synthesis of 3,4-dihydropyrimidine-2-(1H)-Ones/Thiones via Biginelli Reaction under Solvent-free Conditions. Preprints2021, 2021050493. https://doi.org/10.20944/preprints202105.0493.v1
Al-Wahaibi, L.H.; Abdelhamid, A.A.; Saber, S.A.; Elkanzi, N.A.; Ali, A.M. Pumice as a Novel Nature Heterogeneous Catalyst for Synthesis of 3,4-dihydropyrimidine-2-(1H)-Ones/Thiones via Biginelli Reaction under Solvent-free Conditions. Preprints 2021, 2021050493. https://doi.org/10.20944/preprints202105.0493.v1
Al-Wahaibi, L.H.; Abdelhamid, A.A.; Saber, S.A.; Elkanzi, N.A.; Ali, A.M. Pumice as a Novel Nature Heterogeneous Catalyst for Synthesis of 3,4-dihydropyrimidine-2-(1H)-Ones/Thiones via Biginelli Reaction under Solvent-free Conditions. Preprints2021, 2021050493. https://doi.org/10.20944/preprints202105.0493.v1
APA Style
Al-Wahaibi, L.H., Abdelhamid, A.A., Saber, S.A., Elkanzi, N.A., & Ali, A.M. (2021). Pumice as a Novel Nature Heterogeneous Catalyst for Synthesis of 3,4-dihydropyrimidine-2-(1H)-Ones/Thiones via Biginelli Reaction under Solvent-free Conditions. Preprints. https://doi.org/10.20944/preprints202105.0493.v1
Chicago/Turabian Style
Al-Wahaibi, L.H., Nadia A.A. Elkanzi and Ali M. Ali. 2021 "Pumice as a Novel Nature Heterogeneous Catalyst for Synthesis of 3,4-dihydropyrimidine-2-(1H)-Ones/Thiones via Biginelli Reaction under Solvent-free Conditions" Preprints. https://doi.org/10.20944/preprints202105.0493.v1
Abstract
Abstract: An efficient and environmentally Pumice as a new catalyst for designing of 3,4- dihydropyrimidin-2(1H) ones / thiones via one-pot multi component condensation of aromatic aldehydes, urea/ thiourea and ethyl acetoacetate or acetyl acetone in excellent yields (96-99 %). The advantages using of this new catalyst is very cheap, available, non-toxic, stable under thermal conditions, easy work-up, improved yields, the product of reaction is very pure without using chromatographic methods and solvent free conditions.
Keywords
One pot reaction; 3,4- Dihydropyrimidin-2(1H) ones / thiones and Pumice
Subject
Chemistry and Materials Science, Analytical Chemistry
Copyright:
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
