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Preprint ARTICLE | doi:10.20944/preprints202003.0356.v1

Initial Review and Analysis of COVID-19 Host Genetics and Associated Phenotypes

Yosuke Tanigawa, Manuel Rivas

Subject: Biology And Life Sciences, Biochemistry And Molecular Biology Keywords: COVID-19; SARS-CoV-2; host genetics; genetics; polygenic risk score

Online: 24 March 2020 (08:36:20 CET)

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Preprint ARTICLE | doi:10.20944/preprints202302.0414.v1

All-Cause Mortality According to COVID-19 Vaccination Status: an analysis of the UK Office for National Statistics Public Data

Alberto Donzelli, Giovanni Malatesta, Giovanni Di Palmo, Marco Cosentino, Marco Alessandria

Subject: Medicine And Pharmacology, Immunology And Allergy Keywords: COVID-19; COVID-19 vaccinations; all-cause mortality; relative risk

Online: 24 February 2023 (02:03:36 CET)

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Preprint ARTICLE | doi:10.20944/preprints201804.0130.v1

Modeling the Population Health Impact of Introducing a Modified Risk Tobacco Product into the U.S. Market

Smilja Djurdjevic, Peter N. Lee, Rolf Weitkunat, Zheng Sponsiello-Wang, Frank Lüdicke, Gizelle Baker

Subject: Medicine And Pharmacology, Complementary And Alternative Medicine Keywords: public; tobacco; risk; modified; reduced; nicotine; non-combustible; health; smoking; harm

Online: 10 April 2018 (15:53:43 CEST)

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Working Paper ARTICLE

Respiratory Virus Infection Is A High-risk Factor for Developing Coronavirus Disease 2019 (COVID-19)

MIngyue Chen, Wenxiu Wang, JIng Yu, Zhou Wang, Xiaofeng Zheng, Mingshu Han, Youwei Zhang, LEi Zhang

Subject: Biology And Life Sciences, Virology Keywords: COVID-19; influenza; SARS-CoV-2; ACE2; risk factor

Online: 16 October 2020 (11:49:13 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202012.0598.v1

Prevalence and Risk Factors of Smoking Among Health Care Workers and Non-Health Care Workers in Zambezi Region, Namibia: A Cross-Sectional Study

Sylvia Kahimbi Mahoto, Kabwebwe Honoré Mitonga, Olanrewaju Oladimeji

Subject: Social Sciences, Psychology Keywords: Zambezi; Health Care Workers; cigarette smoking; Cigarettes; Gender differences; Prevalence; Tobacco use; Vulnerable populations; Risk factors

Online: 23 December 2020 (16:28:15 CET)

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Smoking is a major risk factor for non-communicable diseases and remains a significant public health challenge in many lower- and middle-income countries (LMIC) including Namibia. The purpose of the study was to estimate the prevalence of smoking and its associated risk factors among HCWs and non-HCWs in Zambezi region. An exploratory cross-sectional survey was conducted between March and October 2020 among residents of the eight (8) constituencies of Zambezi region. Four hundred and sixty-one (461) respondents who had been residents of the selected constituencies for over five years and aged between 17-60 years were selected for the study. The main outcome measure was current cigarette smoking status. Descriptive statistics were used to summarize the socio-demographic characteristics of the respondents. We stratified data analysis by individual being health workers or non-health workers. A bivariate Pearson Chi-square test was used to determine the association between socio-demographic characteristics and the smoking status. Statistically significant variables in the bivariate analysis were used as predictors in the univariate and multivariate models. The response rate of potential participants was 95% (n=434). The mean (±SD) age of participant’s was 32.5 (± 11.34 years). Significant relationships were observed between smoking status and area of residency (constituency), gender, age category, level of education, age of onset of smoking and the daily smoking frequency. The majority of smokers (n=108) were none-HCWs with males being the majority (n=62). Age (p=0.001), education levels (p=0.001) and area of residency (p=0.022) were highly associated with smoking among none-HCW while marital status was associated with smoking among HCWs (p=0.013). In the final multivariate model, the odds of smoking among female non-HCWs were significantly lower (OR: 0.386; 95% CI: 0.228 – 0.655). Furthermore, the odds of smoking among this same group were lower among those who had secondary level education (OR: 0.178; 95% CI: 0.0659 – 0.483), post-secondary (OR: 0.117, 95% CI: 0.0412 – 0.330) and first stage tertiary (OR: 0.306: 95% CI: 0.106 – 0.881) compared to those who had primary school education. In conclusion, smoking prevalence among none HCWs and HCWs working in Zambezi included in the study was similar to that of the general Namibian population but higher than other neighboring countries within SADC. The results showed a need for the establishment of specific smoking related strategies that target HCWs to address smoking use parallel to the running of none HCWs which would ultimately decrease the smoking prevalence and improve health.

Preprint ARTICLE | doi:10.20944/preprints202003.0440.v1

COVID-19: A Drug Repurposing and Biomarker Identification by Using Comprehensive Gene-Disease Associations through Protein-Protein Interaction Network Analysis

Suresh Kumar

Subject: Biology And Life Sciences, Virology Keywords: COVID-19; SARS-CoV-2; 2019-nCoV; novel corona virus; drug repurposing; chloroquine; high-risk group; asymptomatic

Online: 30 March 2020 (07:24:16 CEST)

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COVID-19 (2019-nCoV) is a pandemic disease with an estimated mortality rate of 3.4% (estimated by the WHO as of March 3, 2020). Until now there is no antiviral drug and vaccine for COVID-19. The current overwhelming situation by COVID-19 patients in hospitals is likely to increase in the next few months. About 15 percent of patients with serious disease in COVID-19 require immediate health services. Rather than waiting for new anti-viral drugs or vaccines that take a few months to years to develop and test, several researchers and public health agencies are attempting to repurpose medicines that are already approved for another similar disease and have proved to be fairly effective. This study aims to identify FDA approved drugs that can be used for drug repurposing and identify biomarkers among high- risk and asymptomatic groups. In this study gene-disease association related to COVID-19 reported mild, severe symptoms and clinical outcomes were determined. The high-risk group was studied related to SARS-CoV-2 viral entry and life cycle by using Disgenet and compared with curated COVID-19 gene data sets from the CTD database. The overlapped gene sets were enriched and the selected genes were constructed for protein-protein interaction networks. Through interactome, key genes were identified for COVID-19 and also for high risk and asymptomatic groups. The key hub genes involved in COVID-19 were VEGFA, TNF, IL-6, CXCL8, IL10, CCL2, IL1B, TLR4, ICAM1, MMP9. The identified key genes were used for drug-gene interaction for drug repurposing. The chloroquine, lenalidomide, pentoxifylline, thalidome, sorafenib, pacitaxel, rapamycin, cortisol, statins were proposed to be probable drug repurposing candidates for the treatment of COVID-19. However, these predicted drug candidates need to be validated through randomized clinical trials. Also, a key gene involved in high risk and the asymptomatic group were identified, which can be used as probable biomarkers for early identification.

Preprint BRIEF REPORT | doi:10.20944/preprints202005.0084.v1

Nsp7 and Spike Glycoprotein of SARS-CoV-2 Are Envisaged as Potential Targets of Vitamin D and Ivermectin

Jhimli Dasgupta, Udayaditya Sen, Abhisek Bakshi, Abhijit Dasgupta, Krishnendu Manna, Chinmay Saha, Rajat K. De, Satinath Mukhopadhyay, Nitai P. Bhattacharyya

Subject: Biology And Life Sciences, Virology Keywords: SARS-CoV-2; Vitamin D; Ivermectin; RNA-dependent-RNA polymerase; Spike glycoprotein; Knowledge based docking

Online: 5 May 2020 (15:18:30 CEST)

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COVID-19 has emerged as deadly pandemic worldwide with no vaccine or suitable antiviral drugs to prevent or cure the disease. Because of the time-consuming process to develop new vaccines or antiviral agents, there has been a growing interest in repurposing some existing drugs to combat SARS-CoV-2. Vitamin D is known to be protective against acute respiratory distress syndrome (ARDS), pneumonia and cytokine storm. Recently it has been used as a repurposed drug for the treatment of H5N1 virus-induced lung injury. Circumstantial evidences indicate that people with low level of vitamin D are more susceptible to SARS-CoV-2. Although, vitamin D was suggested to interfere with viral replication, its interaction with any SARS-CoV-2 protein is unexplored yet. Beside this, ivermectin, a well-known anti-parasitic agent, exhibits potent anti-viral activities in vitro against viruses such as HIV-1 and dengue. Very recently, ivermectin has been found to reduce viral load of SARS-CoV-2 in vitro. We have analyzed available structures of SARS-CoV-2 proteins to identify probable binding partner(s) of vitamin D and ivermectin through knowledge-based docking studies and figured out possible implication of their binding in SARS-CoV-2 infection. Our observations suggest that the non-structural protein nsp7 possesses a potential site to house 25-hydroxyvitamin D3 (VDY) or the active form of Vitamin D, calcitrol. Binding of vitamin D with nsp7 likely to hamper the formation of nsp7-nsp8 complex which is required to bind with RNA dependent RNA polymerase (RdRP), nsp12 for optimal function. On the other hand, potential binding site of ivermectin has been identified in the S2 subunit of trimeric spike(S) glycoprotein of SARS-CoV-2. We propose that deeply inserted mode of ivermectin binding at three inter-subunit junctions may restrict large scale conformational changes of S2 helices which is necessary for efficient fusion of viral and host membrane. Our study, therefore, opens up avenues for further investigations to consider vitamin D and ivermectin as potential drugs against SARS-CoV-2.

Preprint ARTICLE | doi:10.20944/preprints201903.0104.v1

Cyber Risk in IoT Systems

Petar Radanliev, David Charles De Roure, Carsten Maple, Jason R.C. Nurse, Razvan Nicolescu, Uchenna Ani

Subject: Engineering, Control And Systems Engineering Keywords: cyber risk; Internet of Things; cyber risk impact assessment; cyber risk estimation; cyber risk insurance

Online: 8 March 2019 (08:50:49 CET)

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Preprint REVIEW | doi:10.20944/preprints201612.0027.v1

Robots to the Rescue: A Review of Studies on Differential Medical Diagnosis Employing Ontology-Based Chat Bot Technology

Bosede Iyiade Edwards, Idris Oladele Muniru, Adrian David Cheok

Subject: Medicine And Pharmacology, Other Keywords: chatbot technology; ontology-based systems; expert systems; diagnosis; conversational agents; robotics; human-robot interaction; physician-patient relationship; intelligent agents

Online: 6 December 2016 (04:46:32 CET)

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Preprint ARTICLE | doi:10.20944/preprints202002.0097.v1

PyRosetta Jupyter Notebooks Teach Biomolecular Structure Prediction and Design

Kathy Le, Jared Adolf-Bryfogle, Jason Klima, Sergey Lyskov, Jason Labonte, Steven Bertolani, Shourya Roy Burman, Andrew Leaver-Fay, Brian Weitzner, Jack Maguire, Ramya Rangan, Matt Adrianowycz, Rebecca Alford, Aleexan Adal, Morgan Nance, Rhiju Das, Roland Dunbrack, William Schief, Brian Kuhlman, Justin Siegel, Jeffrey Gray

Subject: Biology And Life Sciences, Biochemistry And Molecular Biology Keywords: Protein structure and dynamics; Molecular structure and modeling; Protein and macromolecules; Computational methods and bioinformatics; Computer-based teaching tools; Learning materials and teaching tools; Multimedia teaching tools

Online: 7 February 2020 (11:42:09 CET)

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Preprint REVIEW | doi:10.20944/preprints202104.0383.v1

Future of Construction Industry: COVID-19 and Its Implications on Construction Projects and Risk Management – A Review

Kushal Adhikari, Lochana Poudyal

Subject: Engineering, Automotive Engineering Keywords: COVID-19; pandemic; construction project; risk management; use of technology; recovery and resilience

Online: 14 April 2021 (14:12:17 CEST)

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Working Paper REVIEW

Controlled COVID-19 Infection in Hospitals Could Achieve A Safer Exit Strategy in the Near-Term: Assessing Risks and Benefits

Eleftherios Diamandis

Subject: Public Health And Healthcare, Health Policy And Services Keywords: COVID-19 infection; immunity; risk of COVID-19 infection; pandemics; outbreaks; voluntary infection

Online: 13 May 2020 (05:53:07 CEST)

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Preprint BRIEF REPORT | doi:10.20944/preprints202005.0094.v1

Covid-19 Situation in Bangladesh

Abdul Kader Mohiuddin

Subject: Public Health And Healthcare, Health Policy And Services Keywords: COVID-19 Lockdown; Shortage of PPEs; Global Pandemic Crisis; Incentives for Officials at Risk

Online: 6 May 2020 (08:45:39 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202106.0470.v1

River Influx Drives Heavy Metal Pollution in Manila Bay, Philippines: An Insight from Multivariate Analyses

Reymar Diwa, Custer Deocaris, Lawrence Belo

Subject: Environmental And Earth Sciences, Atmospheric Science And Meteorology Keywords: heavy metals; surface sediment; Manila Bay; pollution; multivariate analysis; ecological risk

Online: 18 June 2021 (08:32:18 CEST)

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Preprint COMMUNICATION | doi:10.20944/preprints202004.0536.v1

Hedging Feasibility Perspectives against the COVID-19 for the International Tourism Sector

Angeliki N. Menegaki

Subject: Business, Economics And Management, Economics Keywords: corona-virus; COVID-19; tourism sector; review; risk hedging

Online: 30 April 2020 (14:15:28 CEST)

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Preprint REVIEW | doi:10.20944/preprints202205.0180.v1

Replacing Sustainable Development: Potential Frameworks for International Cooperation in an Era of Increasing Crises and Disasters.

Jem Bendell

Subject: Social Sciences, Safety Research Keywords: Sustainable Development; Sustainable Development Goals; Sustainability; Postdevelopment; Degrowth; Disaster Risk Reduction; United Nations; Permacrisis; Metadisaster.

Online: 13 May 2022 (07:48:45 CEST)

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Preprint ARTICLE | doi:10.20944/preprints201710.0169.v1

A Longitudinal Approach to Biological Psychiatric Research: The PsyCourse Study

Monika Budde, Heike Anderson-Schmidt, Katrin Gade, Daniela Reich-Erkelenz, Kristina Adorjan, Janos L. Kalman, Fanny Senner, Sergi Papiol, Till F. M. Andlauer, Ashley L. Comes, Eva C. Schulte, Farah Klöhn-Saghatolislam , Anna Gryaznova, Maria Hake, Kim Bartholdi, Laura Flatau, Markus Reitt, Silke Quast, Sophia Stegmaier, Milena Meyers, Barbara Emons, Ida Sybille Haußleiter, Georg Juckel, Vanessa Nieratschker, Udo Dannlowski, Max Schmauß, Jörg Zimmermann, Jens Reimer, Sybille Schulz, Jens Wiltfang, Eva Reininghaus, Ion-George Anghelescu, Volker Arolt, Bernhard T. Baune, Carsten Konrad, Andreas Thiel, Andreas J. Fallgatter, Christian Figge, Martin von Hagen, Manfred Koller, Fabian U. Lang, Moritz E. Wigand, Thomas Becker, Markus Jäger, Detlef E. Dietrich, Sebastian Stierl, Harald Scherk, Carsten Spitzer, Here Folkerts, Stephanie H. Witt, Franziska Degenhardt, Andreas J. Forstner, Marcella Rietschel, Markus M. Nöthen, Peter Falkai, Thomas G. Schulze, Urs Heilbronner

Subject: Medicine And Pharmacology, Psychiatry And Mental Health Keywords: Schizophrenia; bipolar; psychosis; depression; polygenic risk score; diagnosis; RDoC

Online: 27 October 2017 (11:58:11 CEST)

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Preprint ARTICLE | doi:10.20944/preprints201808.0352.v2

AutoCloud+, a “Universal” Physical and Statistical Model-Based 2D Spatial Topology-Preserving Software Toolbox for Cloud/Cloud-Shadow Detection in Multi-Sensor Single-Date Earth Observation Multi-Spectral Imagery Eligible for Systematic ESA EO Level 2 Product Generation

Andrea Baraldi, Dirk Tiede

Subject: Environmental And Earth Sciences, Remote Sensing Keywords: artificial intelligence; color naming; color constancy; cognitive science; computer vision; object-based image analysis (OBIA); physical and statistical data models; radiometric calibration; semantic content-based image retrieval; spatial topological and spatial non-topological information components

Online: 28 August 2018 (07:57:02 CEST)

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Preprint ARTICLE | doi:10.20944/preprints201811.0326.v2

Cell-Based Fish: A Novel Approach to Seafood Production and an Opportunity for Cellular Agriculture

Natalie Rubio, Isha Datar, David Stachura, Kate Krueger

Subject: Biology And Life Sciences, Biochemistry And Molecular Biology Keywords: cellular agriculture; cell-based seafood; fish tissue culture; bioreactor; serum-free media; ocean conservation; marine cell culture; aquaculture

Online: 25 January 2019 (11:36:58 CET)

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Cellular agriculture is defined as the production of agricultural products from cell cultures rather than from whole plants or animals. With growing interest in cellular agriculture as a means to address the public health, environmental, and animal welfare challenges of animal agriculture, the concept of producing seafood from fish cell- and tissue-cultures is emerging as a means to address similar challenges with industrial aquaculture systems and marine capture. Cell-based seafood - as opposed to animal-based seafood - can combine developments in biomedical engineering with modern aquaculture techniques. Biomedical engineering developments such as closed-system bioreactor production of land animal cells create a basis for large scale production of marine animal cells. Aquaculture techniques such as genetic modification and closed system aquaculture have achieved marked gains in production that can pave the way for innovations in cell-based seafood production. Here, we present the current state of innovation relevant to the development of cell-based seafood across multiple species as well as specific opportunities and challenges that exist for advancing this science. The authors find that the physiological properties of fish cell- and tissue- culture may be uniquely suited to cultivation in vitro. These physiological properties, including hypoxia tolerance, high buffering capacity, and low-temperature growth conditions, make marine cell culture an attractive opportunity for scale production of cell-based seafood; perhaps even more so than mammalian and avian cell cultures for cell-based meats. This, coupled with the unique capabilities of crustacean tissue-friendly scaffolding such as chitosan, a common seafood waste product and mushroom derivative, presents great promise for cell-based seafood production via bioreactor cultivation. To become fully realized, cell-based seafood research will require more understanding of fish muscle culture and cultivation; more investigation into serum-free media formulations optimized for fish cell culture; and bioreactor designs tuned to the needs of fish cells for large scale production.

Preprint ARTICLE | doi:10.20944/preprints201903.0128.v1

An Updated Review on the Epidemiology, Pathophysiology, Etiology and Diagnosis of Liver Cirrhosis

Gee Young Geong, Sun Hyung Kang, Chang Min Lee

Subject: Medicine And Pharmacology, Gastroenterology And Hepatology Keywords: Liver cirrhosis; epidemiology; etiology; risk factors; pathophysiology; diagnosis.

Online: 11 March 2019 (09:44:18 CET)

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Preprint REVIEW | doi:10.20944/preprints202006.0216.v2

Detection and Survival of SARS-coronavirus in Human Stool, Urine, Wastewater and Sludge

Andrew Singer, Rachel Wray

Subject: Biology And Life Sciences, Virology Keywords: SARS-coronavirus; Severe Acute Respiratory Syndrome; COVID-19; Stool; Urine; Wastewater; Wastewater-based epidemiology

Online: 18 June 2020 (09:29:00 CEST)

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Preprint ARTICLE | doi:10.20944/preprints201810.0203.v2

Global Recognition of the Importance of Nature-Based Solutions to Climate Change Impacts

Nathalie Seddon, Elizabeth Daniels, Rowan Davis, Rian Harris, Xiaoting Hou-Jones, Saleemul Huq, Valerie Kapos, Georgina M. Mace, Ali Raza Rizvi, Hannah Reid, Dilys Roe, Sylvia Wicander

Subject: Environmental And Earth Sciences, Ecology Keywords: biodiversity; climate change adaptation; ecosystems; Paris agreement; policy; nature-based solutions

Online: 14 September 2019 (12:07:15 CEST)

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Preprint ARTICLE | doi:10.20944/preprints201707.0042.v1

Health Risk Assessment of VOCs from Surgical Smoke

Shaohua She, Gang Lu, Wah Yang, Mianwei Hong, Lingfei Zhu

Subject: Public Health And Healthcare, Public, Environmental And Occupational Health Keywords: surgical smoke; volatile organic compounds (VOCs); health risk assessment (HRA); carcinogenic

Online: 17 July 2017 (07:40:18 CEST)

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Preprint ARTICLE | doi:10.20944/preprints201812.0077.v1

Why Nature-Based Solutions to Climate Change Must Be Grounded in Sound Biodiversity Science

Nathalie Seddon, Beth Turner, Pam Berry, Alexandre Chausson, Cécile A.J. Girardin

Subject: Environmental And Earth Sciences, Ecology Keywords: biodiversity; climate change; forests; nature-based solutions; policy; resilience

Online: 6 December 2018 (07:39:13 CET)

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Preprint ARTICLE | doi:10.20944/preprints201903.0080.v1

Definition of Internet of Things (IoT) Cyber Risk – Discussion on a Transformation Roadmap for Standardisation of Regulations, Risk Maturity, Strategy Design and Impact Assessment

Petar Radanliev, David De Roure, Jason R.C. Nurse, Pete Burnap, Eirini Anthi, Uchenna Ani, La’Treall Maddox, Omar Santos, Rafael Mantilla Montalvo

Subject: Engineering, Control And Systems Engineering Keywords: Internet of Things; Micro Mart model; Goal-Oriented Approach; transformation roadmap; Cyber risk regulations; empirical analysis; cyber risk self-assessment; cyber risk target state

Online: 6 March 2019 (11:47:04 CET)

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Preprint ARTICLE | doi:10.20944/preprints201903.0094.v1

New Developments in Cyber Physical Systems, the Internet of Things and the Digital Economy – Discussion on Future Developments in the Industrial Internet of Things and Industry 4.0

Petar Radanliev, David De Roure, Jason R.C. Nurse, Razvan Nicolescu, Michael Huth, Stacy Cannady, Rafael Mantilla Montalvo

Subject: Engineering, Control And Systems Engineering Keywords: Internet of Things; Cyber Physical Systems; Digital Economy; Industrial Internet of Things; Industry 4.0; empirical analysis; cyber risk assessment; cyber risk target state

Online: 7 March 2019 (12:25:15 CET)

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Working Paper REVIEW

Review of Potential High-Leverage and Inexpensive Mitigations for Reducing Risk in Epidemics and Pandemics

David Manheim, David Denkenberger

Subject: Public Health And Healthcare, Health Policy And Services Keywords: Mitigation; Risk Reduction; Global Catastrophic Biological Risk; Epidemics; Disease X; Literature Review; Pandemics; Value of Information; Existential Risk

Online: 28 February 2020 (12:32:33 CET)

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Preprint ESSAY | doi:10.20944/preprints202003.0370.v1

Essential Indicators for Measuring Area-Based Conservation Effectiveness in the Post-2020 Global Biodiversity Framework

Jonas Geldmann, Marine Deguignet, Andrew Balmford, Neil D. Burgess, Nigel Dudley, Marc Hockings, Naomi Kingston, Helen Klimmek, Alanah Hayley Lewis, Carsten Rahbek, Sue Stolton, Claire Vincent, Sue Wells, Stephen Woodley, James E.M. Watson

Subject: Environmental And Earth Sciences, Environmental Science Keywords: 2011-2020 Strategic Plan for Biodiversity; biodiversity outcomes; indicators; management effectiveness; other effective area-based conservation measures; post-2020; protected areas

Online: 25 March 2020 (04:31:56 CET)

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Preprint ARTICLE | doi:10.20944/preprints202107.0306.v1

Online vs. Face-to-Face Lecture Courses: Factors Impacting the Effectiveness of Online Learning

Piyapong Janmaimool, Siriphan Nunsunanon

Subject: Business, Economics And Management, Accounting And Taxation Keywords: online learning; face-to-face learning; learning effectiveness; challenges with online learning; lecture-based courses.

Online: 13 July 2021 (11:57:22 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202007.0346.v1

A Hundred Lives Lost: Doctor Deaths in India During the Times of COVID-19

Rajeev Jayadevan

Subject: Biology And Life Sciences, Virology Keywords: COVID-19; deaths; doctor; nurse; pharmacist; healthcare worker; frontline; occupational risk; suicide; violent death; accident; pandemic; SARS-CoV-2

Online: 16 July 2020 (08:28:55 CEST)

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Preprint ARTICLE | doi:10.20944/preprints201608.0132.v1

Case-Based Study of Metrics Derived from Instrumented Fall Risk Assessment Tests

Anabela Martins, Joana Silva, António Santos, João Madureira, Carlos Alcobia, Luís Ferreira, Pedro Mendes, Cláudia Tonelo, Catarina Silva, Daniela Baltazar, Inês Sousa

Subject: Medicine And Pharmacology, Other Keywords: fall risk assessment; risk of falling; force platforms; inertial sensors.

Online: 12 August 2016 (09:32:28 CEST)

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Preprint ARTICLE | doi:10.20944/preprints201608.0069.v1

Comparison of Pixel- and Object-Based Approaches in Phenology-Based Rubber Plantation Mapping in Fragmented Landscapes

Deli Zhai, Jinwei Dong, Georg Cadisch, Mingcheng Wang, Weili Kou, Jianchu Xu, Xiangming Xiao

Subject: Environmental And Earth Sciences, Environmental Science Keywords: Rubber (Hevea brasiliensis) plantation; phenology; Xishuangbanna; Landsat; object-based approach; pixel-based approach

Online: 6 August 2016 (11:54:28 CEST)

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Preprint COMMUNICATION | doi:10.20944/preprints202004.0146.v1

Virtual Screening of Potential Inhibitors for SARS-CoV-2 Main Protease

Carlos Javier Alméciga-Díaz, Luisa N. Pimentel-Vera, Angela Caro, Angela Mosquera, Camilo Andrés Castellanos Moreno, Juan Pablo Manosalva Rojas, Diana Carolina Díaz-Tribaldos

Subject: Biology And Life Sciences, Biochemistry And Molecular Biology Keywords: Coronavirus Disease 2019; SARS-CoV-2; main protease; molecular docking-based virtual screening

Online: 9 April 2020 (09:34:45 CEST)

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Preprint ARTICLE | doi:10.20944/preprints201609.0014.v1

Decreasing Trends in HIV Testing among Adults in Georgia: Analysis of the 2010-2014 BRFSS Data

Benjamin E. Ansa, Sashia White, Yunmi Chung, Selina A. Smith

Subject: Biology And Life Sciences, Virology Keywords: HIV/AIDS; testing; trends; Behavioral Risk Factor Surveillance System; socio-demographic; Georgia

Online: 5 September 2016 (11:21:36 CEST)

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Preprint ARTICLE | doi:10.20944/preprints201712.0150.v1

Probability Distribution of Philippine Daily Rainfall Data

Vanessa Althea B. Bermudez, Ariel Bettina B. Abilgos, Diane Carmeliza N. Cuaresma, Jomar F. Rabajante

Subject: Environmental And Earth Sciences, Atmospheric Science And Meteorology Keywords: Philippines; rainfall; precipitation; Gamma distribution; probability; weather risk

Online: 21 December 2017 (04:43:17 CET)

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Preprint ARTICLE | doi:10.20944/preprints201807.0244.v1

Sentinel-1 and Sentinel-2 Data Fusion for Mapping and Monitoring Wetlands

Gordana Kaplan, Ugur Avdan

Subject: Environmental And Earth Sciences, Remote Sensing Keywords: Image Fusion, Sentinel-1, Sentinel-2, Wetlands, Object-Based Classification, Unmanned Aerial Vehicle

Online: 13 July 2018 (17:11:07 CEST)

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Wetlands benefits can be summarized but are not limited to their ability to store floodwaters and improve water quality, providing habitats for wildlife and supporting biodiversity, as well as aesthetic values. Over the past few decades, remote sensing and geographical information technologies has proven to be a useful and frequent applications in monitoring and mapping wetlands. Combining both optical and microwave satellite data can give significant information about the biophysical characteristics of wetlands and wetlands` vegetation. Also, fusing data from different sensors, such as radar and optical remote sensing data, can increase the wetland classification accuracy. In this paper we investigate the ability of fusion two fine spatial resolution satellite data, Sentinel-2 and the Synthetic Aperture Radar Satellite, Sentinel-1, for mapping wetlands. As a study area in this paper, Balikdami wetland located in the Anatolian part of Turkey has been selected. Both Sentinel-1 and Sentinel-2 images require pre-processing before their use. After the pre-processing, several vegetation indices calculated from the Sentinel-2 bands were included in the data set. Furthermore, an object-based classification was performed. For the accuracy assessment of the obtained results, number of random points were added over the study area. In addition, the results were compared with data from Unmanned Aerial Vehicle collected on the same data of the overpass of the Sentinel-2, and three days before the overpass of Sentinel-1 satellite. The accuracy assessment showed that the results significant and satisfying in the wetland classification using both multispectral and microwave data. The statistical results of the fusion of the optical and radar data showed high wetland mapping accuracy, with an overall classification accuracy of approximately 90% in the object-based classification. Compared with the high resolution UAV data, the classification results give promising results for mapping and monitoring not just wetlands, but also the sub-classes of the study area. For future research, multi-temporal image use and terrain data collection are recommended.

Preprint ARTICLE | doi:10.20944/preprints201608.0068.v1

Effectiveness of Public and Co-operative Health Insurance Models in Nepal: A Concurrent Mixed Study

Chhabi Ranabhat, Chun-Bae Kim, Myung-Bae Park

Subject: Public Health And Healthcare, Public Health And Health Services Keywords: community-based health insurance; cooperative; benefit package; social inclusion; healthcare; Nepal

Online: 6 August 2016 (11:54:03 CEST)

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Background: Health insurance (HI) run by government is providing health care service to large population. Due to poor accountability, participation and sustainability, cooperative health insurance is becoming more popular and effective in low and middle income and some high-income countries too. In Nepal, there are public and cooperative HI is in practice. The aim of this study is to compare the effectiveness of public (government) and cooperative HI in relation to benefit packages, population coverage, inclusiveness, health care utilization, and promptness for treatment in these two health insurance models in Nepal. Method: This is an institution based concurrent mixed study consists of qualitative and quantitative variables from public and cooperative groups. We included all public HI operated by government hospitals and cooperatives groups those purchased hospital service in contract. Two separate study tools were applied to access the effectiveness of insurance models. The key questions were asked for the representatives of government and private health insurance. The numeric information consisted of in quantitative data and subjective response was included in qualitative approach. Descriptive statistics and Mean Whitney U test was applied in numeric data and qualitative information were analyzed by inductive approach Results: The study revealed that new enrolment was not increased, health care utilization rate was increased and the benefit package was almost same in both groups. The overall inclusiveness was higher for the government HI, but enrolment from the religious minority, proportion of negotiated amount during treatment were significantly higher (p<0.05). During illness, the response time to reach hospital was significantly faster in cooperative health insurance than government health insurance. Qualitative findings showed that level of participation, accountability, transparency and recording system was better in cooperative health insurance than public. Conclusion: Cooperative HI could be more sustainable and accountable to the community for all; low, middle and high-income countries.

Preprint BRIEF REPORT | doi:10.20944/preprints202311.1897.v1

Where Does the EU-Path on NGTs Lead Us?

Finja Bohle, Robin Schneider, Juliane Mundorf, Luise Zühl, Samson Simon, Margret Engelhard

Subject: Biology And Life Sciences, Biology And Biotechnology Keywords: NGT; GMO; EC Proposal; Regulation; Environmental Impact; CRISPR-Cas; Environmental Risk Assessment; ERA

Online: 30 November 2023 (05:28:46 CET)

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Preprint ARTICLE | doi:10.20944/preprints201609.0028.v2

Intra-Urban Mobility in the Estimation of Risk Scenarios by BTEX Emissions

Marco Antonio Garcia-Zarate, María Evarista Arellano-García, Mariana Villada Canela, Patricia Aceves-Calderon, Ana Erika Ruiz-Arellano, Christine Alysse Von- Glascoe, M. C. Arredondo Garcia

Subject: Environmental And Earth Sciences, Environmental Science Keywords: VOC; technological risk; exposure to risks; DRI; risk mapping; SIG; BTEX

Online: 13 September 2016 (03:42:52 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202010.0432.v1

COVID-19 Pandemic and Tourism: The Impact of Health Risk Perception and Intolerance of Uncertainty on Travel Intentions

Anastasiya Golets, Jéssica Farias, Ronaldo Pilati, Helena Costa

Subject: Business, Economics And Management, Accounting And Taxation Keywords: COVID-19; pandemic; travel intentions; health risk perception; intolerance of uncertainty

Online: 21 October 2020 (11:11:43 CEST)

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Preprint COMMUNICATION | doi:10.20944/preprints201710.0041.v3

Development and Introduction of the Risk-Sentience Auxiliary Framework (RSAF) as an Enabler to the ISO 31000 and ISO 31010 for High-Risk Environments

Jerry Selvaseelan

Subject: Social Sciences, Safety Research Keywords: uncertainty management; risk management; safety; ISO 31000:2009; ISO 31010:2009; risk management framework; risk-sentience; safety culture; risk culture; enterprise risk management

Online: 19 June 2018 (12:58:28 CEST)

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Preprint CONCEPT PAPER | doi:10.20944/preprints202104.0560.v1

Microbiome-Inspired Green Infrastructure (MIGI): A Bioscience Roadmap for Urban Ecosystem Health

Jake Robinson, Harry Watkins, Ioana Man, Craig Liddicoat, Ross Cameron, Brenda Parker, Marcos Cruz, Laura Meagher

Subject: Biology And Life Sciences, Anatomy And Physiology Keywords: MIGI; microbiome-inspired green infrastructure; microbiome; urban microbiome; nature-based intervention; biodiversity; greenspace; green infrastructure; multispecies urbanism; EcoHealth

Online: 21 April 2021 (09:01:13 CEST)

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Preprint ARTICLE | doi:10.20944/preprints201611.0149.v1

Social License to Operate and Adaptive Co-Marketing: Exchange, Social Capital and Community-Based Social Marketing

Colin Michael Hall, Helena Power

Subject: Business, Economics And Management, Marketing Keywords: adaptive co-marketing; social marketing; community-based social marketing; social license to operate; community engagement; corporate social responsibility; marketing strategy

Online: 30 November 2016 (05:13:35 CET)

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Working Paper ARTICLE

Design Of a Dynamic and Self-Adapting System, Supported With Artificial Intelligence, Machine Learning and Real-Time Intelligence For Predictive Cyber Risk Analytics in Extreme Environments- Cyber Risk in the Colonisation of Mars

Petar Radanliev

Subject: Computer Science And Mathematics, Artificial Intelligence And Machine Learning Keywords: Artificial intelligence; machine learning; real-time probabilistic data; for cyber risk; super forecasting; red teaming;

Online: 12 April 2021 (12:18:14 CEST)

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Preprint REVIEW | doi:10.20944/preprints201607.0012.v1

Analysis of Access Control Methods in Cloud Computing

Madhura Mulimani, Rashmi Rachh

Subject: Computer Science And Mathematics, Information Systems Keywords: role-based access control; attribute-based access control; attribute-based encryption

Online: 8 July 2016 (10:12:21 CEST)

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Preprint ARTICLE | doi:10.20944/preprints201610.0080.v1

M-Polynomials and Topological Indices of Titania Nanotubes

Shin Min Kang, Mobeen Munir, Abdul Rauf Nizami, Shazia Rafique, Waqas Nazeer

Subject: Chemistry And Materials Science, Analytical Chemistry Keywords: degree-based topological index; Zagreb index; general Randic index; symmetric division index; M-polynomial, titania nanotubes

Online: 19 October 2016 (12:44:36 CEST)

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Preprint ESSAY | doi:10.20944/preprints202104.0200.v1

Zoonotic Risk Technology Enters the Viral Emergence Toolkit

Colin Carlson, Maxwell Farrell, Zoe Grange, Barbara Han, Nardus Mollentze, Alexandra Phelan, Angela Rasmussen, Gregory Albery, Bernard Bett, David Brett-Major, Lily Cohen, Tad Dallas, Evan Eskew, Anna Fagre, Kristian Forbes, Rory Gibb, Sam Halabi, Charlotte Hammer, Rebecca Katz, Jason Kindrachuk, Renata Muylaert, Felicia Nutter, Joseph Ogola, Kevin Olival, Michelle Rourke, Sadie Ryan, Noam Ross, Stephanie Seifert, Tarja Sironen, Claire Standley, Kishana Taylor, Marietje Venter, Paul Webala

Subject: Biology And Life Sciences, Biochemistry And Molecular Biology Keywords: zoonotic risk; viral emergence; viral ecology; genomics; machine learning; access and benefit sharing; intellectual property law; global health

Online: 7 April 2021 (11:53:59 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202006.0237.v1

Cardiovascular Risk Factors and Evolution of Patients Attended with COVID-19 in a National Reference Hospital from Lima, Peru

Germán V. Valenzuela, Alfonso J. Rodriguez-Morales, Roxana Mamani, Ricardo Ayala, Katherine Pérez, Cynthia Sarmiento, Jessica Calcino, Luis García, José Amado

Subject: Medicine And Pharmacology, Epidemiology And Infectious Diseases Keywords: COVID-19; SARS-CoV-2; risk factors; outcomes; cardiovascular; Latin America.

Online: 19 June 2020 (10:22:50 CEST)

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Preprint ARTICLE | doi:10.20944/preprints201611.0150.v1

3D Printing of Cytocompatible Water-Based Light-Cured Polyurethane with Hyaluronic Acid for Cartilage Tissue Engineering Applications

Ming-You Shie, Wen-Ching Chang, Li-Ju Wei, Yu-Hsin Huang, Chien-Han Chen, Yi-Wen Chen, Yu-Fang Shen

Subject: Chemistry And Materials Science, Biomaterials Keywords: water-based polyurethane; hyaluronic acid; cartilage tissue engineering; scaffold

Online: 30 November 2016 (04:28:15 CET)

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Preprint REVIEW | doi:10.20944/preprints201608.0045.v1

Risks of Climate Change on the Singapore-Malaysia High Speed Rail System

Sazrul Leena Binti Sa’adin, Sakdirat Kaewunruen, David Jaroszweski

Subject: Engineering, Civil Engineering Keywords: railway infrastructure; high-speed rail; tracks; risk; management and monitoring; climate change; global warming; adaptation; operational readiness

Online: 5 August 2016 (05:11:02 CEST)

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Preprint ARTICLE | doi:10.20944/preprints201904.0057.v1

Maternal Ethnicity as Risk Factor for Miscarriage: Evidence from a Six-Year Period Cohort in a University Setting

Stefania Triunfo, Giulia Di Carlo, Alessandra Cellana, Lucia Masini, Michelangela Danza, Antonio Lanzone

Subject: Medicine And Pharmacology, Obstetrics And Gynaecology Keywords: miscarriage; fetal loss; risk factor; ethnicity; maternal race

Online: 4 April 2019 (15:52:25 CEST)

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Preprint ARTICLE | doi:10.20944/preprints201608.0155.v1

2DCBS: A Model for Developing Dependable Component-Based Software

Hasan Kahtan, Nordin Abu Bakar, Rosmawati Nordin, Mansoor Abdullateef Abdulgabber

Subject: Computer Science And Mathematics, Computer Science Keywords: component-based software development; dependability attributes; availability; reliability; integrity; confidentiality; safety; maintainability

Online: 15 August 2016 (12:21:45 CEST)

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Working Paper REVIEW

Ten Golden Rules for Reforestation to Optimise Carbon Sequestration, Biodiversity Recovery and Livelihood Benefits

Alice Di Sacco, Kate Hardwick, David Blakesley, Pedro H. S. Brancalion, Elinor Breman, Loic Cecilio Rebola, Susan Chomba, Kingsley Dixon, Stephen Elliott, Godfrey Ruyonga, Kirsty Shaw, Paul Smith, Rhian J. Smith, Alexandre Antonelli

Subject: Biology And Life Sciences, Forestry Keywords: Afforestation; Climate change mitigation; Ecological Restoration; Forest landscape restoration; Large-scale tree planting; Natural regeneration; Nature-based solutions; Stakeholders participation

Online: 5 September 2020 (08:01:43 CEST)

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Preprint REVIEW | doi:10.20944/preprints201804.0066.v1

Cybercrime and Risks for Cyber Physical Systems: A Review

Abel Yeboah-ofori, Jamal-Deen Abdulai, Ferdinand Katsriku

Subject: Computer Science And Mathematics, Information Systems Keywords: cyber physical systems; cybercrime; risk mitigation; risk management; industrial control systems

Online: 5 April 2018 (06:10:06 CEST)

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Cyber Physical Systems (CPS) is the integration of computation and physical process that makes a complete system such as the physical components, networked systems, embedded computers and software and linking together of devices and sensors for information sharing. Cyber Physical Systems are Smart Systems that comprises of the merging and integration of Industry Control Systems, Critical Infrastructures, Internet of Things (IoT) and Embedded Systems. Major industries such as the Chemical and Industrial Plants, Aviation Systems, National Grid, the Stock Exchange, Military Systems, and others depends heavily on these Cyber Physical Systems for financial and economic growth. The benefits of CPS nationally and globally are in the areas of Manufacturing, Energy, Transport, Healthcare and Communication. Cyber Physical Systems incorporates Physical systems, Digital systems and Human elements on network infrastructures to provide interactive systems. However, these three key components the Physical systems, Digital systems and Human elements may have inherent threats and vulnerabilities on them that may run the risk of being compromise, exploited, attacked or hacked. Cybercriminals in their quest to bring down these systems and may cause disruption of services either for fame, revenge, political motive, economic war, cyber terrorism and cyber war. The study seeks to review the risks that are associated with these three key components Physical systems, Digital systems and Human elements. The study considered four main risk mitigation goals for this purpose, and these are Business Value, Organizational Requirements, Threat Agent and Impact based on the review results. We used Analytical Hierarchical Process (AHP) to determine the relative importance of these goals that contributes to developing cybercrime and rich in CPS. For the results, the prioritized goals are then used to assess the risks using a semi-quantitative approach to determine the net threat level.

Preprint ARTICLE | doi:10.20944/preprints201611.0054.v1

A Hierarchal Risk Assessment Model using the Evidential Reasoning Rule

Xiaoxiao Ji, Jiang Jiang, Jianbin Sun, Yu-wang Chen

Subject: Computer Science And Mathematics, Information Systems Keywords: Risk assessment; Evidential reasoning; Fire/explosion

Online: 9 November 2016 (10:29:29 CET)

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Preprint REVIEW | doi:10.20944/preprints202008.0478.v1

Risk Assessment of SARS-CoV-2 in Antarctic Wildlife

Andrés Barbosa, Arvind Vansani, Virginia Morandini, Wray Grimaldi, Ralph E.T. Vanstreels, Julia I. Diaz, Thierry Boulinier, Meagan Dewar, Daniel Gonzalez-Acuña, Rachel Gray, Clive R. McMahon, Gary Miller, Michelle Power, Amandine Gamble, Michelle Wille

Subject: Biology And Life Sciences, Virology Keywords: Antarctica; coronavirus; COVID-19; mitigation measures; reverse zoonoses; risk assessment; SARS-CoV-2; wildlife

Online: 21 August 2020 (09:21:25 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202110.0336.v1

Can Nature-Based Solutions Deliver a Win-Win for Biodiversity and Climate Change Adaptation?

Isabel Key, Alison Smith, Beth Turner, Alexandre Chausson, Cécile Girardin, Megan MacGillivray, Nathalie Seddon

Subject: Biology And Life Sciences, Ecology, Evolution, Behavior And Systematics Keywords: nature-based solutions; climate change adaptation; biodiversity; ecosystem-based adaptation

Online: 23 October 2021 (14:19:30 CEST)

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Nature-based solutions (NbS) are increasingly recognised for their potential to address both the climate and biodiversity crises. These outcomes are interdependent, and both rely on the capacity of NbS to support and enhance the health of an ecosystem: its biodiversity, the condition of its abiotic and biotic elements, and its capacity to function normally despite environmental change. However, while understanding of ecosystem health outcomes of nature-based interventions for climate change mitigation is growing, the outcomes of those implemented for adaptation remain poorly understood with evidence scattered across multiple disciplines. To address this, we conducted a systematic review of the outcomes of 109 nature-based interventions for climate change adaptation using 33 indicators of ecosystem health across eight broad categories (e.g. diversity, biomass, ecosystem functioning and population dynamics). We showed that 88% of interventions with positive outcomes for climate change adaptation also reported measurable benefits for ecosystem health. We also showed that interventions were associated with a 67% average increase in local species richness. All eight studies that reported benefits in terms of both climate change mitigation and adaptation also supported ecosystem health, leading to a triple win. However, there were also trade-offs, mainly for forest management and creation of novel ecosystems such as monoculture plantations of non-native species. Our review highlights two major limitations of research to date. First, only a limited selection of metrics are used to assess ecosystem health and these rarely include key aspects such as functional diversity and habitat connectivity. Second, taxonomic coverage is poor: 67% of outcomes assessed only plants and 57% did not distinguish between native and non-native species. Future research addressing these issues will allow the design and adaptive management of NbS to support healthy and resilient ecosystems, and thereby enhance their effectiveness for meeting both climate and biodiversity targets.

Preprint REVIEW | doi:10.20944/preprints202007.0471.v1

Fecal Shedding of SARS-CoV-2 and Its Potential Role in Person-To-Person Transmission and the Environment-Based Spread of COVID-19

Davey Jones, Marcos Quintela Baluja, David Graham, Alexander Corbishley, James McDonald, Shelagh Malham, Luke Hillary, Thomas Connor, William Gaze, Ines Moura, Mark Wilcox, Kata Farkas

Subject: Biology And Life Sciences, Virology Keywords: bathing waters; coronavirus; environmental transmission; faecal-oral route; infection risk; waterborne illness

Online: 20 July 2020 (12:02:45 CEST)

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The recent detection of SARS-CoV-2 RNA in feces has led to speculation that it can be transmitted via the fecal-oral/ocular route. This review aims to critically evaluate the incidence of gastrointestinal (GI) symptoms, the quantity and infectivity of SARS-CoV-2 in feces and urine, and whether these pose an infection risk in sanitary settings, sewage networks, wastewater treatment plants, and the wider environment (e.g. rivers, lakes and marine waters). Overall, severe GI dysfunction is only evident in a small number of COVID-19 cases, with 11 ± 2% exhibiting diarrhea and 12 ± 3% exhibiting vomiting and nausea. In addition to these cases, SARS-CoV-2 RNA can be detected in feces from some asymptomatic, mildly- and pre-symptomatic individuals. Fecal shedding of the virus peaks in the symptomatic period and can persist for several weeks, but with declining abundances in the post-symptomatic phase. SARS-CoV-2 RNA is occasionally detected in urine, but reports in fecal samples are more frequent. The abundance of the virus genetic material in both urine (ca. 10²-10⁵ gc/ml) and feces (ca. 10²-10⁷ gc/ml) is much lower than in nasopharyngeal fluids (ca. 10⁵-10¹¹ gc/ml). There is strong evidence of multiplication of SARS-CoV-2 in the GI tract and infectious virus has occasionally been recovered from both urine and stool samples. The level and infectious capability of SARS-CoV-2 in vomit remain unknown. In comparison to enteric viruses transmitted via the fecal-oral route (e.g. norovirus, adenovirus), the likelihood of SARS-CoV-2 being transmitted via feces or urine appears lower due to the lower relative amounts of virus present in feces/urine. The biggest risk of transmission will occur in clinical and care home settings where secondary handling of people and urine/fecal matter occurs. In addition, while SARS-CoV-2 RNA genetic material can be detected by in wastewater, this signal is greatly reduced by conventional treatment. Our analysis also suggests the likelihood of infection due to contact with sewage-contaminated water (e.g. swimming, surfing, angling) or food (e.g. salads, shellfish) is extremely low or negligible based on very low predicted abundances and limited environmental survival of SARS-CoV-2. These conclusions are corroborated by the fact that over eight million global cases of COVID-19 have occurred, but exposure to feces or wastewater has never been implicated as a transmission vector.

Preprint ARTICLE | doi:10.20944/preprints201810.0278.v2

Evolution of Microgrids with Converter-Interfaced Generations: Challenges and Opportunities

Md Alamgir Hossain, Hemanshu Roy Pota, Md Jahangir Hossain, Frede Blaabjerg

Subject: Engineering, Energy And Fuel Technology Keywords: converter-based microgrids; distribution networks; renewable energy sources; definitions of microgrids and distributed generation units

Online: 14 February 2019 (04:03:12 CET)

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Preprint REVIEW | doi:10.20944/preprints202101.0297.v1

Carbon-Based Nanomaterials: Promising Antiviral Agents to Combat COVID-19 in the Microbial Resistant Era

Ángel Serrano-Aroca, Kazuo Takayama, Alberto Tuñón-Molina, Murat Seyran, Sk. Sarif Hassan, Pabitra Pal Choudhury, Vladimir N. Uversky, Kenneth Lundstrom, Parise Adadi, Giorgio Palù, Alaa A. A. Aljabali, Gaurav Chauhan, Ramesh Kandimalla, Murtaza M. Tambuwala, Amos Lal, Bruce D. Uhal, Adam M. Brufsky

Subject: Chemistry And Materials Science, Biomaterials Keywords: COVID-19; SARS-CoV-2; carbon-based nanomaterials; antiviral properties; pneumonia

Online: 15 January 2021 (13:30:21 CET)

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Preprint ARTICLE | doi:10.20944/preprints201611.0041.v1

Some Computational Aspects of Triangular Boron Nanotubes

Mobeen Munir, Waqas Nazeer, Shazia Rafique, Abdul Rauf Nizami, Shin Min Kang

Subject: Chemistry And Materials Science, Analytical Chemistry Keywords: M-polynomial; degree-based index; boron nanotubes

Online: 7 November 2016 (07:41:36 CET)

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Preprint ARTICLE | doi:10.20944/preprints201705.0035.v1

A Novel Hybrid Approach Based on Instance Based Learning Classifier and Rotation Forest Ensemble for Spatial Prediction of Rainfall-Induced Shallow Landslides Using GIS

Quang-Khanh Nguyen, Dieu Tien Bui, Nhat-Duc Hoang, Phan Trong Trinh, Viet-Ha Nguyen, Isık Yilmaz

Subject: Environmental And Earth Sciences, Geophysics And Geology Keywords: landslide; classifier ensemble; instance based learning; Rotation Forest; GIS; Vietnam

Online: 4 May 2017 (08:25:12 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202007.0337.v1

Level of Knowledge, Attitude and Perception About COVID-19 Pandemic and Infection Control: A Cross-Sectional Study Among Veterinarians in Nigeria

Olubukola Adenubi, Oluwawemimo Adebowale, Abimbola Oloye, Noah Bankole, Hezekiah Adesokan, Oladotun Fadipe, Patience Ayo-Ajayi, Adebayo Akinloye

Subject: Social Sciences, Government Keywords: COVID-19; Risk; Knowledge; Attitude; Perception; Veterinarian; Nigeria

Online: 15 July 2020 (12:27:50 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202007.0076.v1

Current Challenges of Cold Brew Coffee – Roasting, Extraction, Flavor Profile, Contamination, and Food Safety

Raven Kwok, Kenny Lee Wee Ting, Steffen Schwarz, Linda Claassen, Dirk W. Lachenmeier

Subject: Chemistry And Materials Science, Food Chemistry Keywords: coffee; cold brew; nitro cold brew; roasting; extraction; hygiene; risk assessment; product quality

Online: 5 July 2020 (14:53:27 CEST)

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Preprint CASE REPORT | doi:10.20944/preprints201608.0105.v1

Blending Science and Community Voices for Multi-Scale Disaster Risk Reduction and Climate Resilience: A Participatory Scenario Planning Approach

Alebachew Adem Nurye

Subject: Social Sciences, Geography, Planning And Development Keywords: Climate change; disaster risk reduction; participatory scenario planning; pastoralism; Ethiopia

Online: 10 August 2016 (10:14:00 CEST)

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Preprint ARTICLE | doi:10.20944/preprints201608.0058.v1

Public Perception of Climate Risk: The Case of Greece

Asimina Voskaki, Konstantinos Tsermenidis

Subject: Environmental And Earth Sciences, Environmental Science Keywords: climate risk; climate change; public perception

Online: 6 August 2016 (04:59:47 CEST)

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Preprint ARTICLE | doi:10.20944/preprints201703.0027.v1

A Comprehensive Kinetic Model of Fischer-Tropsch Synthesis over Supported Cobalt Catalyst

Reza Jalilzadeh, Mahmoud Moqadam

Subject: Engineering, Energy And Fuel Technology Keywords: Fischer-Tropsch synthesis; kinetics model; cobalt based catalyst

Online: 6 March 2017 (06:47:14 CET)

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Working Paper ARTICLE

Dynamic Real-Time Risk Analytics of Uncontrollable States in Complex Internet of Things Systems: Cyber Risk at the Edge

Petar Radanliev, David De Roure, Max Van Kleek, Pete Burnap, Eirini Anthi, Jason R.C. Nurse, Omar Santos, Rafael Mantilla Montalvo, La’Treall Maddox

Subject: Engineering, Automotive Engineering Keywords: functional dependency; network-based linear dependency modelling; internet of things; micro mort model; goal-oriented approach; transformation roadmap; cyber risk regulations; empirical analysis; cyber risk self-assessment; cyber risk target state.

Online: 25 December 2020 (11:35:48 CET)

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Preprint ARTICLE | doi:10.20944/preprints202309.0944.v1

Groundwater Quality Assessment of Manipur, India, and Worldwide Bibliometric Analysis of Research Progress on Groundwater Quality

Rakshita Chaudhary, Nisha Gaur, Mohit Yadav

Subject: Environmental And Earth Sciences, Environmental Science Keywords: Groundwater; Water Quality Index; Bacteriological Quality; Irrigational indices; Hydro chemical processes; Potential health risk

Online: 14 September 2023 (08:39:26 CEST)

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Preprint REVIEW | doi:10.20944/preprints201607.0029.v1

(Re)conceptualising Risk: What (Seems to) Work for At-Risk Students

David Zyngier

Subject: Social Sciences, Education Keywords: student risk; social justice; critical pedagogy; critical pedagogy

Online: 14 July 2016 (11:03:29 CEST)

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Preprint ARTICLE | doi:10.20944/preprints201710.0057.v1

Ceramic-Based 4D-Components: Additive Manufacturing (AM) of Ceramic-Based Functionally Graded Materials (FGM) by Thermoplastic 3D-Printing (T3DP)

Uwe Scheithauer, Steven Weingarten, Robert Johne, Eric Schwarzer, Johannes Abel, Hans-Jürgen Richter, Tassilo Moritz, Alexander Michaelis

Subject: Chemistry And Materials Science, Ceramics And Composites Keywords: additive manufacturing (AM); Functionally Graded Materials (FGM); Thermoplastic 3D-Printing (T3DP; ceramics; ceramic-based 4D-components; zirconia; graded microstructure

Online: 10 October 2017 (03:21:04 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202312.1576.v1

The Bacterial Burden of Worn Face Masks – Observational Research and Literature Review

Kai Kisielinski, Barbara Wojtasik, Aleksandra Zalewska, David M Livermore, Agata Jurczak-Kurek

Subject: Biology And Life Sciences, Immunology And Microbiology Keywords: 16S rRNA gene amplicon sequencing; adverse effects; bacterial contamination; fluorescent staining; masks; N95; personal protective equipment; risk; surgical mask

Online: 20 December 2023 (15:14:56 CET)

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Preprint ARTICLE | doi:10.20944/preprints201609.0101.v1

Microstructural Evolution, Thermodynamics and Kinetics of Mo-Tm₂O₃ Powder Mixtures during Ball Milling

Yong Luo, Guang Ran, Nanjun Chen, Qiang Shen, Yaoli Zhang

Subject: Chemistry And Materials Science, Materials Science And Technology Keywords: neutron absorber; Mo-based composites; ball milling; microstructure; thulium oxide

Online: 27 September 2016 (10:45:47 CEST)

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Preprint ARTICLE | doi:10.20944/preprints201611.0073.v1

Evaluation of Satellite Rainfall Estimates in the Pra Basin of Ghana

Collins Owusu, Kwaku Amaning Adjei, Samuel Nii Odai

Subject: Environmental And Earth Sciences, Atmospheric Science And Meteorology Keywords: rainfall; TMPA; CMORPH; Pra basin; satellite-based precipitation; Ghana

Online: 14 November 2016 (07:39:44 CET)

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Preprint ARTICLE | doi:10.20944/preprints201608.0017.v4

Propositions for Confidence Interval in Systematic Sampling on Real Line

Mehmet Niyazi Çankaya

Subject: Computer Science And Mathematics, Mathematics Keywords: biomedical imaging; covariogram; design-based stereology; estimation of volume; systematic sampling

Online: 15 September 2016 (05:18:42 CEST)

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Preprint ARTICLE | doi:10.20944/preprints201903.0109.v2

Cyber Risk impact Assessment - Assessing the Risk from the IoT to the Digital Economy

Petar Radanliev, David De Roure, Jason R.C. Nurse, Razvan Nicolescu, Michael Huth, Stacy Cannady, Rafael Mantilla Montalvo

Subject: Engineering, Control And Systems Engineering Keywords: Cyber risk; Internet of Things cyber risk; Digital Economy Risk Assessment; Economic Impact Assessment.

Online: 9 April 2019 (12:26:13 CEST)

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Preprint ARTICLE | doi:10.20944/preprints201612.0050.v1

Performance Analysis of Data–Driven and Model–Based Control Strategies Applied to a Thermal Unit Model

Cihan Turhan, Silvio Simani, Ivan Zajic, Gulden Gokcen Akkurt

Subject: Engineering, Control And Systems Engineering Keywords: modelling and simulation for control; advanced control design; model–based and data-driven approaches; artificial intelligence; thermal unit nonlinear system

Online: 9 December 2016 (03:17:38 CET)

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Preprint ARTICLE | doi:10.20944/preprints201608.0080.v2

A Mathematical Spline-Based Model of Cardiac Left Ventricle Anatomy and Morphology

Sergei Pravdin

Subject: Computer Science And Mathematics, Applied Mathematics Keywords: left ventricle; myofibre; myocardium structure; rule-based model; mathematical anatomy

Online: 20 October 2016 (08:22:39 CEST)

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Preprint ARTICLE | doi:10.20944/preprints201701.0092.v1

Structuring Climate Adaptation through Multiple Perspectives

Mohanasundar Radhakrishnan, Assela Pathirana, Richard Ashley, Chris Zevenbergen

Subject: Environmental And Earth Sciences, Environmental Science Keywords: climate adaptation; flexibility; flood risk management; urban adaptation

Online: 20 January 2017 (04:25:55 CET)

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Working Paper ARTICLE

Preschoolers’ Development of Understanding Zero

Attila Krajcsi, Petia Kojouharova, Gabor Lengyel

Subject: Social Sciences, Psychology Keywords: numerical cognition; zero; number status of zero; items based number representation

Online: 16 July 2020 (12:35:17 CEST)

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Preprint REVIEW | doi:10.20944/preprints201608.0173.v1

Technologies and Applications Concomitant with Web-Based GIS

Sadiq Mukhtar

Subject: Social Sciences, Geography, Planning And Development Keywords: web-based GIS; application; architectures; technology

Online: 18 August 2016 (06:07:05 CEST)

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Preprint ARTICLE | doi:10.20944/preprints201611.0005.v2

Reshuffling the Risk Factors of Severe Early Childhood Caries

Noha Kabil, Sherif Eltaweil

Subject: Medicine And Pharmacology, Dentistry And Oral Surgery Keywords: severe early childhood caries; risk factors

Online: 3 November 2016 (08:39:30 CET)

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Preprint REVIEW | doi:10.20944/preprints202009.0337.v1

Alcohol-Based Hand Sanitizers – A Multidimensional Perspective

Nasser N. Nyamwweya, Kennedy O. Abuga

Subject: Public Health And Healthcare, Primary Health Care Keywords: hand sanitizers; hand rubs; alcohol based; disinfection; hand hygiene; coronavirus; COVID-19

Online: 15 September 2020 (09:07:09 CEST)

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Preprint REVIEW | doi:10.20944/preprints201908.0316.v1

Airborne Microplastics: A Review Study on Method for Analysis, Occurrence, Movement and Risks

Enyoh Christian Ebere, Verla Andrew Wirnkor, Verla Evelyn Ngozi, Ibe Francis Chizoruo, Amaobi Collins Emeka

Subject: Chemistry And Materials Science, Analytical Chemistry Keywords: air pollution; dermal route; fibers; health risk; inhalation; micropollutants

Online: 30 August 2019 (05:08:43 CEST)

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Preprint ARTICLE | doi:10.20944/preprints201706.0007.v1

Pipeline Leak Detection by Transient-Based Method Using MATLAB® Functions

Albert Carbó-Bech, Salvador A. De Las Heras, Alfredo Guardo

Subject: Engineering, Mechanical Engineering Keywords: pipeline modeling; leak detection; transient-based method; pipeline system

Online: 1 June 2017 (08:20:31 CEST)

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Preprint ARTICLE | doi:10.20944/preprints201704.0146.v1

Early Childhood Dental Caries, Mouth Pain, and Malnutrition in the Ecuadorian Amazon Region

Marvin So, Yianni A. Ellenikiotis, Hannah M. Husby, Cecilia Leonor Paz, Brittany Seymour, Karen Sokal-Gutierrez

Subject: Medicine And Pharmacology, Dentistry And Oral Surgery Keywords: early childhood caries; mouth pain; malnutrition; ecuador; community-based intervention

Online: 24 April 2017 (05:43:03 CEST)

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Preprint ARTICLE | doi:10.20944/preprints201711.0163.v1

A Hybrid MCDM Technique for Risk Management in Construction Projects

Kajal Chatterjee, Edmundas Kazimieras Zavadskas, Jolanta Tamošaitienė, Krishnendu Adhikary, Samarjit Kar

Subject: Engineering, Civil Engineering Keywords: D number, Analytical Network Process (ANP), MABAC, Multi-criteria decision making (MCDM), Consistent fuzzy preference relation (CFPR), Construction project risk, Risk Management

Online: 24 November 2017 (16:46:59 CET)

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Preprint ARTICLE | doi:10.20944/preprints201907.0006.v1

Fuzzy-Based Sentiment Analysis System for Analyzing Student Feedback and Satisfaction

Muhammad Zubair Asghar, Ikram Ullah, Shahab Shamshirband, Fazal Masud Kundi, Ammara Habib

Subject: Computer Science And Mathematics, Applied Mathematics Keywords: student feedback analysis; sentiments opinion words; polarity shifters; lexicon-based

Online: 1 July 2019 (11:17:37 CEST)

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Preprint ARTICLE | doi:10.20944/preprints201704.0142.v1

Retrospective Proteomic Screening of 100 Breast Cancer Tissues

Ida Pucci-Minafra, Gianluca Di Cara, Rosa Musso, Patrizia Cancemi, Nadia Ninfa Albanese, Elena Roz, Salvatore Minafra

Subject: Medicine And Pharmacology, Oncology And Oncogenics Keywords: breast cancer; surgical tissues; gel-based proteomics; mass spectrometry; protein clustering

Online: 24 April 2017 (05:14:06 CEST)

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Preprint ARTICLE | doi:10.20944/preprints201610.0031.v2

The Solvency II Standard Formula, Linear Geometry, and Diversification

Joachim Paulusch

Subject: Computer Science And Mathematics, Applied Mathematics Keywords: Solvency II; Standard Formula; Risk Measure; Diversification; Aggregation; Monotony; Homogeneity; Subadditivity; Euler's Principle; Capital Allocation

Online: 1 March 2017 (08:53:59 CET)

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Preprint ARTICLE | doi:10.20944/preprints202004.0398.v1

Psychosocial, and Socio-Economic Crisis in Bangladesh due to COVID-19 Pandemic: A Perception-Based Assessment

Mashura Shammi, Md. Bodrud-Doza, Abu Reza Md. Towfiqul Islam, Md. Mostafizur Rahman

Subject: Social Sciences, Cognitive Science Keywords: COVID-19; Perception-based questionnaire; principal component analysis (PCA); Linear regression model; social panic; social conflict

Online: 22 April 2020 (09:55:38 CEST)

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Preprint ARTICLE | doi:10.20944/preprints201812.0097.v1

Impacts of the IUCN Red List of Ecosystems on Conservation Policy and Practice

Lucie M. Bland, Emily Nicholson, Rebecca M. Miller, Angela Andrade, Andres Etter, José Rafael Ferrer-Paris, Tytti Kontula, Arild Lindgaard, Patricio Pliscoff, Andrew Skowno, Irene Zager, David A. Keith

Subject: Environmental And Earth Sciences, Ecology Keywords: conservation practice, ecosystem, impact, IUCN Red List of Ecosystems, monitoring, risk assessment

Online: 7 December 2018 (17:50:24 CET)

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Preprint REVIEW | doi:10.20944/preprints201808.0023.v1

Recent Advances in the Direct Synthesis of Hydrogen Peroxide Using Chemical Catalysis – a review

Sumanth Ranganathan, Volker Sieber

Subject: Chemistry And Materials Science, Chemical Engineering Keywords: catalyst; direct synthesis; hydrogen peroxide; Pd based catalyst; reactor engineering; microreactor

Online: 1 August 2018 (14:10:48 CEST)

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Preprint ARTICLE | doi:10.20944/preprints201703.0172.v1

A Study on Coastal Flooding and Risk Assessment under Climate Change in Mid-Western Coast of Taiwan

Tai-Wen Hsu, Dong-Sin Shih, Chi-Yu Li, Yuan-Jyh Lan, Yu-Chen Lin

Subject: Engineering, Civil Engineering Keywords: Climate Change; Coastal Disasters; Vulnerability; Disaster Risk.

Online: 21 March 2017 (16:41:53 CET)

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Preprint ARTICLE | doi:10.20944/preprints201802.0066.v1

Global Correlates of Cardiovascular Risk: A Comparison of 158 Countries

Pavel Grasgruber, Jan Cacek, Eduard Hrazdíra, Sylva Hřebíčková, Martin Sebera

Subject: Medicine And Pharmacology, Cardiac And Cardiovascular Systems Keywords: cardiovascular diseases; risk factors; nutrition; ecological study

Online: 8 February 2018 (03:22:54 CET)

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Preprint ARTICLE | doi:10.20944/preprints201703.0196.v1

A Reliable Turning Process by the Early Use of a Deep Simulation Model at Several Manufacturing Stages

Gorka Urbikain, Luis Norberto López De Lacalle, Mikel Arsuaga, Alvaro Alvarez, Miguel A. Alonso

Subject: Engineering, Industrial And Manufacturing Engineering Keywords: simulation software; manufacturing systems; process integration; machining optimization; Industry 4.0; knowledge-based manufacturing

Online: 27 March 2017 (10:28:34 CEST)

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Preprint REVIEW | doi:10.20944/preprints202005.0058.v1

Towards Engineering Biosystems with Emergent Collective Functions

Thomas E. Gorochowski, Sabine Hauert, Jan-Ulrich Kreft, Lucia Marucci, Namid R. Stillman, T-Y. Dora Tang, Lucia Bandiera, Vittorio Bartoli, Daniel O. R. Dixon, Alex J. H. Fedorec, Harold Fellermann, Alexander G. Fletcher, Tim Foster, Luca Giuggioli, Antoni Matyjaszkiewicz, Scott McCormick, Sandra Montes Olivas, Jonathan Naylor, Ana Rubio Denniss, Daniel Ward

Subject: Biology And Life Sciences, Biology And Biotechnology Keywords: synthetic biology; multi-agent modelling; individual-based modelling; agent-based modelling; systems biology; emergence; multi-scale; bioengineering; consortia; collectives

Online: 5 May 2020 (03:45:16 CEST)

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Preprint ARTICLE | doi:10.20944/preprints201902.0054.v1

Spatiotemporal Heterogeneity in the Distribution of Chikungunya and Zika Virus Case Incidences and Risk Factors During Their Epidemics in Barranquilla, Colombia, between 2014 and 2016: An Ecological Study

Thomas C. McHale, Claudia M. Romero-Vivas, Claudio Fronterre, Pedro Arango-Padilla, Andrew K. Falconar, Naomi R. Waterlow, Chad Nix, Jorge Cano

Subject: Biology And Life Sciences, Virology Keywords: Chikungunya virus, Zika virus, spatial clustering, Bayesian Poisson models, conditional autoregressive models, socioeconomic risk factors, environmental risk factors

Online: 5 February 2019 (14:25:34 CET)

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Preprint ARTICLE | doi:10.20944/preprints201905.0284.v1

Proprietary Algorithms for Polygenic Risk: Protecting Scientific Innovation or Hiding the Lack of It?

A. Cecile J.W. Janssens

Subject: Biology And Life Sciences, Biochemistry And Molecular Biology Keywords: personal genomics, DNA, polygenic, risk, regulation, discrimination, calibration, prediction, transparency, autonomy

Online: 23 May 2019 (16:23:57 CEST)

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Preprint ARTICLE | doi:10.20944/preprints201612.0035.v1

Enhancing Singapore’s Pension Scheme: A Blueprint for Further Flexibility

Koon-Shing Kwong, Yiu-Kuen Tse, Wai-Sum Chan

Subject: Business, Economics And Management, Economics Keywords: inflation risk; investment returns; life annuity; longevity risk; post-retirement benefits

Online: 7 December 2016 (10:27:23 CET)

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