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Preprint ARTICLE | doi:10.20944/preprints201805.0309.v1

Acoustic Design of a Classical Concert Hall and Evaluation of its Acoustic Performance – A Case Study

Kwangbok Jeong, Taehoon Hong, Sung Hoon Kim, Jimin Kim, Sangyoub Lee

Subject: Engineering, Architecture, Building And Construction Keywords: Acoustic design; Reverberation time; Clarity; Lateral fraction; Acoustic measurements; Classical concert hall

Online: 22 May 2018 (13:49:31 CEST)

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Preprint REVIEW | doi:10.20944/preprints201810.0763.v1

Overview of Microbial Fuel Cell (MFC) Recent Advancement from Fundamentals to Applications: MFC Designs, Major Elements, and Scalability

Sami G. A. Flimban, Taeyoung Kim, Iqbal Mohammad Ibrahim Ismail, Sang-Eun Oh

Subject: Engineering, Energy And Fuel Technology Keywords: Microbial fuel cell (MFC); fuel cell elements; design; energy generation; Scaling up; configuration

Online: 2 November 2018 (10:04:38 CET)

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Preprint ARTICLE | doi:10.20944/preprints201807.0581.v1

Prefabricated Hybrid Wall Panel System for Lightweight Steel Construction in Seismic Prone Regions

Pezhman Sharafi, Mina Mortazavi, Bijan Samali, Hamid Ronagh

Subject: Engineering, Civil Engineering Keywords: panelised construction; lightweight frames; hybrid systems; cold formed steel; hot rolled steel; design for earthquake, lateral force resisting system

Online: 30 July 2018 (10:24:10 CEST)

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Preprint ARTICLE | doi:10.20944/preprints201705.0045.v1

Methodology for a Dump Design Optimization in Large-Scale Open Pit Mines

Jorge Puell Ortiz

Subject: Engineering, Control And Systems Engineering Keywords: mine planning; dump design; open pit; optimization

Online: 5 May 2017 (05:29:10 CEST)

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Preprint ARTICLE | doi:10.3390/sci2040077

Atmospheric Temperature and CO<sub>2</sub>: Hen-or-Egg Causality?

Demetris Koutsoyiannis, Zbigniew Kundzewicz

Subject: Environmental And Earth Sciences, Environmental Science Keywords: temperature; global warming; greenhouse gases; atmospheric CO₂ concentration

Online: 20 October 2020 (00:00:00 CEST)

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Preprint ARTICLE | doi:10.20944/preprints201801.0242.v1

A General Design Procedure for Symmetrical Windings of Electrical Machines

Massimo Caruso, Antonino Oscar Di Tommaso, Fabrizio Marignetti, Rosario Miceli, Giuseppe Ricco Galluzzo

Subject: Engineering, Electrical And Electronic Engineering Keywords: Rotating electrical machines; winding design; symmetrical winding; star of slots.

Online: 25 January 2018 (12:18:58 CET)

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Preprint ARTICLE | doi:10.20944/preprints201607.0085.v1

Garments Texture Design Class Identification Using Deep Convolutional Neural Network

S.M. Sofiqul Islam, Emon Kumar Dey, Md. Nurul Ahad Tawhid, B. M. Mainul Hossain

Subject: Computer Science And Mathematics, Artificial Intelligence And Machine Learning Keywords: CNN; Deep Learning; AlexNet; VGGNet; Texture Descriptor; Garment Categories; 13 Garment Trend Identification; Design Classification for Garments.

Online: 27 July 2016 (15:39:53 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202010.0043.v1

ASMD-FSMD Technique for Designing Digital Devices on FPGA

Valery Salauyou

Subject: Computer Science And Mathematics, Algebra And Number Theory Keywords: digital device; finite state machine with datapath; algorithm state machine with datapath; field programmable gate array; design technique; development time; reliability; area; performance

Online: 2 October 2020 (13:54:34 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202309.1541.v1

Factors Influencing Attitudes of University Students towards ChatGPT and its Usage: A Multi-National Study Validating the TAME-ChatGPT Survey Instrument

Maram Abdaljaleel, Muna Barakat, Mariam Alsanafi, Nesreen A. Salim, Husam Abazid, Diana Malaeb, Ali Haider Mohammed, Bassam Abdul Rasool Hassan, Abdulrasool M. Wayyes, Sinan Subhi Farhan, Sami El Khatib, Mohamad Rahal, Ali Sahban, Doaa H. Abdelaziz, Noha O. Mansour, Reem AlZayer, Roaa Khalil, Feten Fekih-Romdhane, Rabih Hallit, Souheil Hallit, Malik Sallam

Subject: Social Sciences, Education Keywords: higher education; technology acceptance; generative pre-trained transformer; curriculum design; academia

Online: 22 September 2023 (08:39:44 CEST)

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Artificial intelligence (AI)-based models hold the potential to transform higher education if adopted properly and ethically. A prime example is ChatGPT with earlier studies indicating its widespread adoption in academia and by university students. The current study aimed to identify the factors influencing the attitude towards ChatGPT and its usage among university students in Arab countries. A previous survey instrument termed Technology Acceptance Model Edited to Assess ChatGPT Adoption (TAME-ChatGPT) was administered online using a convenience-based approach among the contacts of the authors. Confirmatory factor analysis (CFA) for the survey constructs was done using root mean square error of approximation (RMSEA), standardized root mean square residual (SRMR), comparative fit index (CFI), and Tucker-Lewis index (TLI). The final study sample comprised a total of 2240 participant divided as follows: Iraq (n=736, 32.9%), Kuwait (n=582, 26.0%), Egypt (n=417, 18.6%), Lebanon (n=263, 11.7%), and Jordan (n=242, 10.8%). A total of 1048 respondents heard of ChatGPT before the study (46.8%), of which 551 used ChatGPT (52.6%). The mean scores of TAME-ChatGPT constructs showed that the ease of ChatGPT use, positive attitude towards technology and social influence, higher perceived usefulness, the influence of behavioral/cognitive factors, low perceived risks and low anxiety were the determinants of positive attitude to ChatGPT and its use. For both the attitude and usage scales of TAME-ChatGPT, CFA collectively yielded satisfactory fit indices as indicated by low RMSEA and SRMR together with high CFI and TLI. Multivariate analysis showed that attitude to ChatGPT use was significantly influenced by country of residence, age, university type, and the latest grade point average of the students. The current study confirmed the validity of TAME-ChatGPT as a survey instrument to assess the possible determinants of ChatGPT use among university students in Arab countries. The study findings highlighted that successful adoption of ChatGPT in higher education could be dependent on perceived ease of use, usefulness, positive attitudes to technology, social influence, behavioral/cognitive factors, lower anxiety, and minimal perceived risks. The utility of ChatGPT in higher education requires policies that should be tailored for various settings, considering the differences observed in attitude towards ChatGPT among participating students in this study.

Preprint ARTICLE | doi:10.20944/preprints201801.0077.v1

A Methodology for Design and Analysis of Sensor Fusion with Real Data in UAV Platforms

Jesús García, Jose Manuel Molina, Jorge Trincado

Subject: Engineering, Electrical And Electronic Engineering Keywords: UAVs sensor fusion; EKF; real data analysis; system design

Online: 9 January 2018 (07:47:45 CET)

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Preprint REVIEW | doi:10.20944/preprints201611.0101.v1

Forest Protected Area Systems and Biodiversity Conservation in Bangladesh

Sharif Ahmed Mukul, A. Z. M. Manzoor Rashid, Niaz Ahmed Khan

Subject: Environmental And Earth Sciences, Environmental Science Keywords: biodiversity conservation, livelihood, co-management, stakeholder, law enforcement

Online: 18 November 2016 (15:20:07 CET)

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Preprint REVIEW | doi:10.20944/preprints201806.0421.v1

CO₂ Pipeline Design: A Review

Suoton P. Peletiri, Nejat Rahmanian, Iqbal M. Mujtaba

Subject: Engineering, Energy And Fuel Technology Keywords: CCS; CO2 pipeline design; pressure drop; pipeline diameter models; CO2 transportation; diameter equation

Online: 26 June 2018 (13:00:01 CEST)

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Preprint ARTICLE | doi:10.20944/preprints201609.0085.v2

Modeling and Simulation of Passenger Flow Distribution in Urban Rail Transit Hub Platform

Long Gao, Limin Jia

Subject: Computer Science And Mathematics, Computational Mathematics Keywords: passenger flow distribution model; simulation design; performance evaluation; passenger flow volume; service level; urban rail transit hub platform

Online: 2 December 2016 (07:52:00 CET)

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Preprint ARTICLE | doi:10.20944/preprints202002.0071.v1

Drug and Vaccine Design against Novel Coronavirus (2019-nCoV) Spike Protein through Computational Approach

Suresh Kumar

Subject: Biology And Life Sciences, Virology Keywords: 2019-nCoV; novel corona virus; Wuhan virus; drug; vaccine; spike protein; epitope; vaccine design

Online: 5 February 2020 (15:34:15 CET)

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Preprint ARTICLE | doi:10.20944/preprints201807.0441.v1

A Feasibility Review of innovative Prefabricated Footing Systems for Residential Structures

Bertrand Teodosio, Shanaka Kristombu Baduge, Tuan Duc Ngo, Priyan Mendis, Maral Tecer, David Heath

Subject: Engineering, Architecture, Building And Construction Keywords: prefabricated footing system; residential structures; reactive soils; modular construction; design for manufacture and assembly

Online: 24 July 2018 (05:45:06 CEST)

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Preprint ARTICLE | doi:10.20944/preprints201611.0149.v1

Social License to Operate and Adaptive Co-Marketing: Exchange, Social Capital and Community-Based Social Marketing

Colin Michael Hall, Helena Power

Subject: Business, Economics And Management, Marketing Keywords: adaptive co-marketing; social marketing; community-based social marketing; social license to operate; community engagement; corporate social responsibility; marketing strategy

Online: 30 November 2016 (05:13:35 CET)

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Preprint REVIEW | doi:10.20944/preprints202005.0376.v1

Computational Strategies to Combat COVID-19: Useful Tools to Accelerate SARS-CoV-2 and Coronavirus Research

Franziska Hufsky, Kevin Lamkiewicz, Alexandre Almeida, Abdel Aouacheria, Cecilia Arighi, Alex Bateman, Jan Baumbach, Niko Beerenwinkel, Christian Brandt, Marco Cacciabue, Sara Chuguransky, Oliver Drechsel, Robert D. Finn, Adrian Fritz, Stephan Fuchs, Georges Hattab, Anne-Christin Hauschild, Dominik Heider, Marie Hoffmann, Martin Hölzer, Stefan Hoops, Lars Kaderali, Ioanna Kalvari, Max von Kleist, René Kmiecinski, Denise Kühnert, Gorka Lasso, Pieter Libin, Markus List, Hannah F. Löchel, Maria J. Martin, Roman Martin, Julian Matschinske, Alice C. McHardy, Pedro Mendes, Jaina Mistry, Vincent Navratil, Eric Nawrocki, Áine Niamh O'Toole, Nancy Palacios-Ontiveros, Anton I. Petrov, Guillermo Rangel-Piñeros, Nicole Redaschi, Susanne Reimering, Knut Reinert, Alejandro Reyes, Lorna Richardson, David L. Robertson, Sepideh Sadegh, Joshua B. Singer, Kristof Theys, Chris Upton, Marius Welzel, Lowri Williams, Manja Marz

Subject: Biology And Life Sciences, Virology Keywords: virus bioinformatics; SARS-CoV-2; sequencing; epidemiology; drug design; tools

Online: 23 May 2020 (11:01:11 CEST)

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Preprint ARTICLE | doi:10.20944/preprints201701.0019.v1

The BCC/B2 Morphologies in AlxNiCoFeCr High-Entropy Alloys

Yue Ma, Beibei Jiang, Chunling Li, Qing Wang, Chuang Dong, Peter K Liaw, Fen Xu, Lixian Sun

Subject: Chemistry And Materials Science, Materials Science And Technology Keywords: high-entropy alloys; Al-Ni-Co-Fe-Cr alloys; microstructure; precipitation morphology; mechanical property

Online: 4 January 2017 (10:30:17 CET)

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Preprint ARTICLE | doi:10.20944/preprints201608.0148.v1

Design and Optimization of an Efficient (96.1%) and Compact (2 kW/dm³) Bidirectional Isolated Single-Phase Dual Active Bridge Ac–Dc Converter

Jordi Everts

Subject: Engineering, Electrical And Electronic Engineering Keywords: ac–dc power converters; battery chargers; dual active bridge; DAB; optimal design; power MOSFETs; single-stage

Online: 15 August 2016 (11:06:09 CEST)

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Working Paper ARTICLE

Macromolecular Modeling and Design in Rosetta: New Methods and Frameworks

Julia Koehler Leman, Brian D Weitzner, Steven M Lewis, RosettaCommons Consortium, Richard Bonneau

Subject: Chemistry And Materials Science, Theoretical Chemistry Keywords: structure prediction; Rosetta; computational modeling; protein design

Online: 16 October 2019 (05:40:52 CEST)

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Preprint ARTICLE | doi:10.20944/preprints201808.0391.v1

Effect of Energy Balance Evaluation on Conceptual Design of Electric and Hybrid Aircraft

Jozsef Rohacs, Daniel Rohacs

Subject: Engineering, Mechanical Engineering Keywords: full electric aircraft; hybrid aircraft; energy and mass balance equations; conceptual design; constraints

Online: 22 August 2018 (05:13:14 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202104.0789.v1

Catcalling As a Representation of the Strong Patriarchal Culture in the Perspective of Feminism

Meilisa Dwi Ervinda, Raselly Elfa Putri, Moses Pandin

Subject: Social Sciences, Gender And Sexuality Studies Keywords: catcalling, harassment; patriarchy; qualitative design; women

Online: 30 April 2021 (15:19:44 CEST)

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Preprint REVIEW | doi:10.20944/preprints201907.0323.v1

Biophilic Architecture for Restoration and Therapy within the Built Environment: A Review

Farhan Asim, Venu Shree

Subject: Social Sciences, Cognitive Science Keywords: biophilia; biophilic design; sustainability; sustainable architecture; built environment; well-being; restorative environment

Online: 28 July 2019 (17:24:11 CEST)

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Preprint ARTICLE | doi:10.20944/preprints201807.0517.v3

Robust Product Design: A Modern View of Quality Engineering in Manufacturing Systems

Amir Parnianifard

Subject: Engineering, Industrial And Manufacturing Engineering Keywords: Robust Design, Taguchi Method, Product Design, Manufacturing Systems, Quality Engineering, Quality Loss Function.

Online: 25 August 2022 (08:36:39 CEST)

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Preprint ARTICLE | doi:10.20944/preprints201608.0183.v3

Creole Hens and Ranga-Ranga: Campesino Foodways and Biocultural Resource-Based Development in the Central Valley of Tarija, Bolivia

Katherine L. Turner, Iain J. Davidson-Hunt, Annette Aurélie Desmarais, Ian Hudson

Subject: Social Sciences, Geography, Planning And Development Keywords: biocultural resources; biocultural design; alternative food networks; sustainable rural development; local food systems; Bolivia

Online: 8 September 2016 (10:19:43 CEST)

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Preprint ARTICLE | doi:10.20944/preprints201608.0027.v1

(T,N) and Residual Fuzzy Co-Implication in Dual Heyting Algebra with Applications

Iqbal H. Jebril

Subject: Computer Science And Mathematics, Analysis Keywords: Fuzzy implications; (S,N) implication; residuum t-norm; (T,N) co-implication; residual co-implication

Online: 3 August 2016 (08:29:47 CEST)

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Preprint ARTICLE | doi:10.20944/preprints201712.0076.v1

Design and Manufacturing of Conformal Cooling for Hot Stamping Dies Using Hybrid Process of Laser Metal Deposition (LMD) and Milling

Magdalena Cortina, Jon Iñaki Arrizubieta, Amaia Calleja, Eneko Ukar, Amaia Alberdi

Subject: Engineering, Industrial And Manufacturing Engineering Keywords: additive manufacturing; laser metal deposition; hot stamping; die and mold; conformal cooling; design optimization.

Online: 12 December 2017 (15:24:24 CET)

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Preprint ARTICLE | doi:10.20944/preprints201608.0026.v1

Propose of Mix Design Method for CO₂ Reduction Concrete Using the Regression Analysis

Tae Hyoung Kim

Subject: Engineering, Civil Engineering Keywords: concrete; sustainability; regression analysis mix design; CO2 emission; cost

Online: 3 August 2016 (06:05:26 CEST)

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Preprint ARTICLE | doi:10.20944/preprints201609.0003.v1

Bio-Inspired Manufacturing Multi-Agent System for Control and Coordination of AGV Systems

Branislav Micieta, Lukas Durica, Vladimira Binasova

Subject: Engineering, Industrial And Manufacturing Engineering Keywords: industrial automation; autonomous design; multi-agent systems; industry 4.0; biologically inspired techniques; AGV systems; energy efficiency

Online: 1 September 2016 (10:48:48 CEST)

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Preprint REVIEW | doi:10.20944/preprints202003.0182.v1

Escape Education: A Systematic Review on Escape Rooms in Education

Alice Veldkamp, Liesbeth van de Grint, Marie-Christine Knippels, Wouter van Joolingen

Subject: Social Sciences, Education Keywords: escape room; escape game; game design; team work; collaborative learning; student engagement

Online: 11 March 2020 (10:25:22 CET)

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Preprint ARTICLE | doi:10.20944/preprints202003.0291.v1

Co-infection of Coronavirus Disease 2019 and Influenza: A Report from Iran

Zohre Khodamoradi, Mohsen Moghadami, Mehrzad Lotfi

Subject: Medicine And Pharmacology, Epidemiology And Infectious Diseases Keywords: co-infection; coronavirus disease 2019; COVID-19; influenza

Online: 19 March 2020 (02:00:47 CET)

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Preprint ARTICLE | doi:10.20944/preprints201605.0003.v1

Poly(lactide-co-glycolide)/Hydroxyapatite Porous Scaffold with Microchannels for Bone Regeneration

Ning Zhang, Yang Wang, Wenpeng Xu, Yong Hu, Jianxun Ding

Subject: Chemistry And Materials Science, Polymers And Plastics Keywords: poly(lactide-co-glycolide); hydroxyapatite; porous scaffold; microchannel; cell ingrowth; mass exchange; bone tissue engineering

Online: 27 May 2016 (11:25:30 CEST)

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Preprint ARTICLE | doi:10.20944/preprints201611.0123.v1

Shifting Paradigm of Governance in the Natural Resources Management of Bangladesh: A Centralist to Pluralistic Approach in the Forest Protected Areas Management

A. Z. M. Manzoor Rashid, Donna Craig, Sharif Ahmed Mukul

Subject: Biology And Life Sciences, Forestry Keywords: co-management; livelihoods; conflicts; biodiversity conservation; sustainable development

Online: 24 November 2016 (11:25:34 CET)

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Good governance in natural resource management (NRM) is one of the most challenging issues in developing countries that often inappropriately embedded in national policies and political agendas. It is, in fact, even more important for countries like Bangladesh with exceptionally high pressure and dependence on its natural resources for sustaining rural livelihoods. Globally, nowadays, good governance is considered as one of the key factor for achieving the goal of sustainable development and biodiversity conservation. Bangladesh, of late has responded to that global zeal by involving local communities in the management of country’s declining forest and other natural resources. The colonial legacy of the forestry sector of Bangladesh was planned and, managed as interim projects through donors’ prescriptions. Thus, institutions, management processes and conservation outcomes were problematic. The conventional approach adopted by colonial and post-colonial regimes for forest management also proved to be inefficient due to its top-down management system. The absolute dependency on donor support, and their prescription sometimes worsened the situation both ecologically and socially. Global, regional and local trends supported the need for a different dimension in the governance paradigms. The introduction of a pluralistic approach, known as co-management in protected areas (PAs) is an example of an attempt whereby shared governance mechanism are implemented to attain the desired goals of conservation that will also address the livelihoods and aspirations of communities living in and around PAs of the country. However, in designing future forest and PA regimes the concern of the external aid support and attached conditions remain a reality that needs to be addressed. Adequate attention should be given to our vanishing biodiversity, culture and community livelihoods through devising an appropriate governance mechanism recognizing and supporting local rights, access and participation in the environmental management. It is now time to mainstream the adhoc nature of governance according to our national conservation strategy and policy frameworks in order to achieve the goals and objectives of the Bangladesh NRM sector addressing the human and community right of people in the specific context of forest protected areas management.

Preprint TECHNICAL NOTE | doi:10.20944/preprints201608.0047.v1

Toughness of Railroad Concrete Crossties with Holes and Web Opening

Erosha K. Gamage, Sakdirat Kaewunruen, Alex M. Remennikov, Tetsuya Ishida

Subject: Engineering, Civil Engineering Keywords: Concrete sleeper; crosstie; design standard; holes; web opening; railway infrastructure; static performance

Online: 5 August 2016 (08:06:33 CEST)

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Preprint ARTICLE | doi:10.20944/preprints201712.0011.v1

Restaurant Acoustics – the Science behind Verbal Communication in Eating Establishments

Jens Holger Rindel

Subject: Physical Sciences, Acoustics Keywords: Verbal communication; Lombard effect; Cocktail party effect; Noise; Acoustic capacity; Universal design

Online: 1 December 2017 (18:22:36 CET)

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Preprint ARTICLE | doi:10.20944/preprints201805.0228.v1

Design PV Tracking System According to Efficiency in Function of Orientation

José Ruelas, Benjamin Pusch, Flavio Muños, Juan Delfin, Francisco Javier Ochoa Estrella

Subject: Engineering, Energy And Fuel Technology Keywords: PV solar tracker; design methodology; efficiency function of orientation

Online: 16 May 2018 (09:51:44 CEST)

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Preprint ARTICLE | doi:10.20944/preprints201704.0148.v1

Multi-objective Optimization of Draft Tube in Francis Turbine Using DOE, RBF and NSGA-II

Chol Nam Mun, De Chun Ba, Xiang Ji Yue, Myong Il Kim

Subject: Engineering, Energy And Fuel Technology Keywords: francis turbine; draft tube; optimization design; experiment of design; non–dominated sorting genetic algorithm

Online: 24 April 2017 (10:52:28 CEST)

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Preprint ARTICLE | doi:10.20944/preprints201801.0158.v1

A Systematic Literature Mining of Sponge City: What Has Been Done and The Challenges Standing Ahead

Zongmin Li, Shuyan Xu, Liming Yao

Subject: Engineering, Control And Systems Engineering Keywords: Sponge city; Active, Beautiful, Clean water design; sustainable drainage systems; water-sensitive urban drainage systems; low impact developments; best management practices; literature mining; literature review

Online: 17 January 2018 (12:34:38 CET)

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Preprint ARTICLE | doi:10.20944/preprints202003.0393.v1

Virtual Screening and Molecular Dynamics Simulation Suggest Valproic Acid Co-A could Bind to SARS-CoV2 RNA Depended RNA Polymerase

Neel Sarovar Bhavesh, Anupam Patra

Subject: Biology And Life Sciences, Biophysics Keywords: SARS-CoV2; RNA depended RNA polymerase; Valproic acid Co-A; drug repurposing

Online: 26 March 2020 (15:04:22 CET)

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Preprint REVIEW | doi:10.20944/preprints202104.0572.v1

From Conventional to Virtual Smile Design Systems: A Current Systematic Review

Mohamed Ahmed, Mohamed Tharwat, Abdelrahman Sanad, Karim Abdelhamid, Hager Ali, Raafat Tammam

Subject: Medicine And Pharmacology, Immunology And Allergy Keywords: Digital Smile Design; digital dentistry; dentistry software; dentistry design software

Online: 21 April 2021 (11:46:39 CEST)

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Preprint ARTICLE | doi:10.20944/preprints201708.0014.v1

Co-simulation Framework for on-Chip LIDAR Sensors in a Cyber-physical System

Fernando Castaño, Gerardo Beruvides, Rodolfo E. Haber, Antonio Artuñedo

Subject: Physical Sciences, Mathematical Physics Keywords: sensor-in-the-loop; co-simulation framework; virtual CPS; on-chip LiDAR; obstacle recognition library

Online: 4 August 2017 (14:13:13 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202008.0442.v1

Observed and Potential Environmental Impacts of COVID -19 in Africa

Nyarai Mupatsi

Subject: Environmental And Earth Sciences, Environmental Science Keywords: COVID-19, SARS-Co-V-2, Environment, Africa, Pandemic,Pollution

Online: 20 August 2020 (07:42:57 CEST)

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Preprint ARTICLE | doi:10.20944/preprints201707.0044.v1

A Comprehensive Technological Survey on Dependable Self-Managing CPS: The Decade of Researches on Correctness and Dependability

Peng Zhou, Kunmean HOU, Zhan Zhang, Decheng Zuo, Jian Dong, Jianjin Li, Haiyin Zhou

Subject: Engineering, Control And Systems Engineering Keywords: cyber physical systems; industry 4.0; MDE; hardware and software co-design; lifetime verification & validation; dependability; correctness; flexibility; self-management; self-adapting; self-healing

Online: 17 July 2017 (10:27:33 CEST)

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Preprint ARTICLE | doi:10.20944/preprints201608.0017.v4

Propositions for Confidence Interval in Systematic Sampling on Real Line

Mehmet Niyazi Çankaya

Subject: Computer Science And Mathematics, Mathematics Keywords: biomedical imaging; covariogram; design-based stereology; estimation of volume; systematic sampling

Online: 15 September 2016 (05:18:42 CEST)

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Preprint ARTICLE | doi:10.20944/preprints201612.0143.v1

None Operational Amplifier (OPA) Based: Design of Analogous Bandgap Reference Voltage

Hao-Ping Chan, Yu-Cherng Hung

Subject: Engineering, Electrical And Electronic Engineering Keywords: Band-gap voltage reference; voltage reference; circuit design

Online: 29 December 2016 (15:47:33 CET)

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Preprint REVIEW | doi:10.20944/preprints202010.0053.v1

Building a High Customer Experience Management Organization: Towards Customer-Centricity

Lamin B. Ceesay

Subject: Business, Economics And Management, Accounting And Taxation Keywords: customer experience; customer-centricity; customer experience design; and integrated customer experience strategy

Online: 5 October 2020 (08:14:04 CEST)

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Preprint ARTICLE | doi:10.20944/preprints201612.0114.v1

Optimal Design of Safety Instrumented Systems for Pressure Control of Methanol Separation Columns in the Bisphenol A Manufacturing Process

In-Bok Lee, Insung Woo

Subject: Chemistry And Materials Science, Chemical Engineering Keywords: relief system; safety instrumented system; pressure relief valve; safety integrity level; minimize design capacity

Online: 23 December 2016 (10:12:59 CET)

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Preprint ARTICLE | doi:10.20944/preprints201610.0083.v1

UPEI-400, a Conjugate of Lipoic Acid and Scopoletin, Mediates Neuroprotection in a Rat Model of Ischemia/Reperfusion

Barry J. Connell, Monique C. Saleh, Desikan Rajagopal, Tarek M. Saleh

Subject: Medicine And Pharmacology, Pathology And Pathobiology Keywords: stroke; antioxidant; co-drug; animal model

Online: 20 October 2016 (08:46:38 CEST)

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Background: Previously, our laboratory has provided evidence that pre-administration of the antioxidant, lipoic acid covalently bonded to various naturally occurring antioxidants, enhanced neuroprotective capacity compared to the administration of lipoic acid on its own. The naturally occurring compound scopoletin, a coumarin derivative, has been shown in various in vitro studies to have both antioxidant and anti-inflammatory mechanism of actions. To date, the effect of scopoletin on neuronal cell death in an in vivo model of ischemia or ischemia-reperfusion has not been investigated. Therefore, the present investigation was designed to determine if scopoletin on its own, or a co-drug consisting of lipoic acid and scopoletin covalent bond, named UPEI-400, would be capable of demonstrating a similar neuroprotective efficacy. Methods: Using a rodent model of stroke in male rats (anesthetized with Inactin®; 100 mg/kg, iv), the middle cerebral artery was permanently occluded for 6 hours (pMCAO), or in separate animals, occluded for 30 min followed by 5.5 hrs of reperfusion (ischemia/reperfusion; I/R). Results: Pre-administration of either scopoletin or UPEI-400 significantly decreased infarct volume in the I/R model (p<0.05), but not in the pMCAO model of stroke. However, UPEI-400 was ~1000 times more potent as compared to scopoletin on its own. The optimal dose of UPEI-400 was then injected during the occlusion and at several time points during reperfusion and significant neuroprotection was observed for up to 150 mins following the start of reperfusion (p<0.05). Conclusion: The data suggest that synthetic combination of scopoletin with lipoic acid (UPEI-400) is a more effective neuroprotectant that either compound on their own. Also, since UPEI-400 was only effective in a model of I/R, it is possible that it may act to enhance neuronal antioxidant capacity and/or upregulate anti-inflammatory pathways to prevent the neuronal cell death.

Preprint ARTICLE | doi:10.20944/preprints201607.0037.v1

THE AVERAGE LOWER 2-DOMINATION NUMBER OF WHEELS RELATED GRAPHS AND AN ALGORITHM

TUFAN TURACI

Subject: Computer Science And Mathematics, Computer Vision And Graphics Keywords: graph vulnerability; connectivity; network design and communication; domination number; average lower 2-domination number

Online: 15 July 2016 (09:50:33 CEST)

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The problem of quantifying the vulnerability of graphs has received much attention nowadays, especially in the field of computer or communication networks. In a communication network, the vulnerability measures the resistance of the network to disruption of operation after the failure of certain stations or communication links. If we think of a graph as modeling a network, the average lower 2-domination number of a graph is a measure of the graph vulnerability and it is defined by

γ_{2 a v} (G) = \frac{1}{| V (G) |} \sum_{v \in V (G)} γ_{2 v} (G)

, where the lower 2-domination number, denoted by

γ_{2 v} (G)

, of the graph G relative to v is the minimum cardinality of 2-domination set in G that contains the vertex v. In this paper, the average lower 2-domination number of wheels and some related networks namely gear graph, friendship graph, helm graph and sun flower graph are calculated. Then, we offer an algorithm for computing the 2-domination number and the average lower 2-domination number of any graph G.

Preprint ARTICLE | doi:10.20944/preprints201810.0608.v1

Investigation of Micro Gas Turbine Systems for High Speed Long Loiter Tactical Unmanned Air Systems

James Large, Apostolos Pesyridis

Subject: Engineering, Mechanical Engineering Keywords: Unmanned Air Vehicles; Micro Gas Turbine Performance; Low Pressure Compressor; Preliminary Design

Online: 25 October 2018 (13:09:17 CEST)

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Preprint ARTICLE | doi:10.20944/preprints201912.0237.v1

Development of Continuum Robot Arm and Gripper for Harvesting Cherry Tomatoes

Azamat Yeshmukhametov, Koichi Koganezawa, Zholdas Buribayev, Yedilkhan Amirgaliyev, Yoshio Yamamoto

Subject: Engineering, Mechanical Engineering Keywords: tomato harvesting; gripper; continuum robot; tomato detection; design; agricultural robot

Online: 18 December 2019 (04:34:30 CET)

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Preprint ARTICLE | doi:10.20944/preprints202002.0372.v1

Structural Genomics and Interactomics of 2019 Wuhan Novel Coronavirus, SARS-CoV-2, Indicate Evolutionary Conserved Functional Regions of Viral Proteins

Hongzhu Cui, Ziyang Gao, Ming Liu, Senbao Lu, Winnie Mkandawire, Oleksandr Narykov, Suhas Srinivasan, Mo Sun, Dmitry Korkin

Subject: Biology And Life Sciences, Virology Keywords: structural genomics; protein-protein interactions; structural bioinformaticscomparative modeling; functional annotation; antiviral design; SARS-CoV-2; 2019-nCoV

Online: 25 February 2020 (11:24:10 CET)

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Preprint REVIEW | doi:10.20944/preprints202206.0014.v1

Microbial Degradation of Pharmaceuticals

Swathi Kandhasamy, Sudha Balraj, Suganya Kanagaraj, Sumathi Sundaravadivelu

Subject: Biology And Life Sciences, Immunology And Microbiology Keywords: pharmaceutical toxicants; recalcitrant pollutants; co-metabolic pathways; biostimulation; bioaug-mentation

Online: 1 June 2022 (10:29:47 CEST)

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Preprint ARTICLE | doi:10.20944/preprints201612.0148.v1

Systemic Analysis of Certified Artisan Cheese Production for Improvement—The Case of the Serra da Estrela PDO Cheese

Denis A. Coelho, Tiago E. P. Carrola, Ana F. Couvinhas

Subject: Engineering, Industrial And Manufacturing Engineering Keywords: process improvement; ewe’s cheese; systemic design

Online: 30 December 2016 (07:34:54 CET)

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The research reported on this paper was aimed at improving the overall efficiency of a PDO certified artisanal cheese production process. Being a PDO certified foodstuff by the EU, it is considered to have properties and qualities determined by the geographical environment in which is made, with its production taking place in a specific and determined geographical location, in this case the Serra da Estrela region. In that sense, the authors conducted a mapping according to a systemic perspective of the processes involved in the context of manufacturing and distribution of certified Serra da Estrela cheese. Numerous methods were used throughout the process, such as a systemic design analysis, and techniques derived from ethnographic methods, which led to the collection of data in the field and consequently provided the immersion of the researcher in genuine work situations. Critical points were identified and emphasized in the systemic map with the purpose of encouraging initiatives to address and overcome the gaps and inefficiencies detected. The systemic design analysis triggered the development of design work. Observations following an ethnographic approach identified ergonomic risks in cheese making during the process of cutting excess chips, fostering the emergence of musculoskeletal disorders at the wrist. A tool that fits best to the task at hand was developed. A prototype of the new tool enabled collecting feedback from use in the work context, in order to inform product development. The domains of agricultural production and microbiology, considering the specific microorganisms developed trough the ripening process of the cheese, turned out to be aspects of high importance for the issue under focus, contributing to a broader understanding of the ripening process and its risks, simultaneously improving the efficiency and success of cheese production. If it were not for the systemic analysis, which served as a link between the boundaries of distinct domains such as the risk of microorganism contamination, ergonomics, energy efficiency, legislation and regulation policies, transportation challenges and economic viability, approached throughout the research. Simultaneously creating bridges between them, the various problems might not have been detected in the first place, as they are usually addressed in specialized disciplines, predetermined by the restrictions of each specific area of knowledge. As a consequence of the development of this research, which was based on an analysis that sought to establish possible connections between various disciplines and tried to constantly maintain a holistic perspective, making new connections and observing the issues from a new angle, apart from the already established methodologies. All this allowed to lay out the seeds for the development of a plan to tackle the critical points identified by the systemic analysis reported in this paper.

Preprint ARTICLE | doi:10.20944/preprints201810.0265.v1

Recognizing and Acknowledging Worldview Diversity in the Inclusive Classroom

Janieta Bartz, Thomas Bartz

Subject: Arts And Humanities, Religious Studies Keywords: inclusion; worldview education; universal design for learning; learning in the presence of the other; reflexive inclusion

Online: 12 October 2018 (11:25:02 CEST)

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Preprint ARTICLE | doi:10.20944/preprints201612.0050.v1

Performance Analysis of Data–Driven and Model–Based Control Strategies Applied to a Thermal Unit Model

Cihan Turhan, Silvio Simani, Ivan Zajic, Gulden Gokcen Akkurt

Subject: Engineering, Control And Systems Engineering Keywords: modelling and simulation for control; advanced control design; model–based and data-driven approaches; artificial intelligence; thermal unit nonlinear system

Online: 9 December 2016 (03:17:38 CET)

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Preprint ARTICLE | doi:10.20944/preprints202202.0079.v1

The Importance of a Natural Social Contract and Co-Evolutionary Governance for Sustainability Transitions

Patrick Huntjens, René Kemp

Subject: Social Sciences, Political Science Keywords: Natural Social Contract; Co-evolutionary governance; Transformative governance; Institutional change; Policy mixes; Transformative Social-Ecological Innovation; Transformative Social Innovation; Social Innovation; Sustainability Transition; Societal Transition

Online: 7 February 2022 (11:43:04 CET)

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Working Paper ARTICLE

Cyber Risk at the Edge: Current and future trends on Cyber Risk Analytics and Artificial Intelligence in the Industrial Internet of Things and Industry 4.0 Supply Chains

Petar Radanliev, David De Roure, Kevin Page, Jason R.C. Nurse, Rafael Mantilla Montalvo, Omar Santos, La'Treall Maddox, Peter Burnap

Subject: Engineering, Automotive Engineering Keywords: Industry 4.0; Supply Chain Design; Transformational Design Roadmap; IIoT Supply Chain Model; Decision Support for Information Management

Online: 24 December 2020 (13:37:35 CET)

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Preprint ARTICLE | doi:10.20944/preprints201705.0056.v1

Power and Obstacle Aware 3D Clock Tree Synthesis

Leena Chandrakar, Ravi S., Harish M. Kittur

Subject: Engineering, Electrical And Electronic Engineering Keywords: Clock Tree Synthesis (CTS); Clock Network Design (CND); Integrated-Circuits (ICs); 3D ICs; Through-Silicon-Via (TSV); obstacles; mmm-algorithm; exact-zero skew algorithm; obstacle aware algorithm; power; wire-length; skew; slew; delay

Online: 8 May 2017 (09:36:47 CEST)

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Preprint REVIEW | doi:10.20944/preprints202004.0217.v1

Medical Basis for Increased Susceptibility of COVID-19 among the Navajo and other Indigenous Tribes

Joseph De Soto, Shazia Hakim

Subject: Medicine And Pharmacology, Epidemiology And Infectious Diseases Keywords: COVID-19; Indigenous Tribes; Co-morbidities; Corona Virus; Navaho

Online: 14 April 2020 (08:43:11 CEST)

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Preprint ARTICLE | doi:10.20944/preprints201902.0121.v1

The Techno-Economic Potential of Offshore Wind Energy with Optimized Future Turbine Designs in Europe

Dilara Gulcin Caglayan, Severin Ryberg, Heidi Heinrichs, Jochen Linßen, Detlef Stolten, Martin Robinius

Subject: Engineering, Energy And Fuel Technology Keywords: Offshore wind energy, future turbine design, floating foundation, fixed-bottom foundation, levelized cost of electricity

Online: 13 February 2019 (15:43:22 CET)

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Preprint REVIEW | doi:10.20944/preprints202109.0373.v1

A Review Paper on ELT Articles Conducted on EFL Teachers’ Perceptions, Practices and Challenges towards Communicative Language Teaching

Netsanet Haymanot Belete

Subject: Social Sciences, Language And Linguistics Keywords: review; article; perception; practice; challenge; design; methodology; findings

Online: 22 September 2021 (10:32:03 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202009.0221.v1

Thermal Performance of Single-Storey Air-welled Terraced House in Malaysia: A Field Measurement Approach

Pau Chung Leng, Mohd Hamdan Ahmad, Dilshan Remaz Ossen, Gabriel Hoh Teck Ling, Eeydzah Aminudin, Weng Howe Chan

Subject: Engineering, Energy And Fuel Technology Keywords: air shaft; air well; solar chimney; field measurement; natural ventilation; tropical climate; terrace house; passive cooling design

Online: 10 September 2020 (04:46:23 CEST)

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The provision requirement of 10% openings of the total floor area stated in the Uniform Building by Law 1984 Malaysia has been practiced by designers for building plan submission approval. However, the effectiveness of thermal performance in landed residential buildings, despite the imposition by the by-law, has never been empirically measured and proven. Although terraced houses in Malaysia have dominated 40.9% of the total property transaction in 2019, such mass production with typical designs hardly provides its occupants with thermal comfort due to the static outdoor air condition and lack of external windows, where the conventional ventilation technique does not work well, even for houses with an air well system. Consequently, the occupants need to rely on mechanical cooling, which is a high energy-consuming component contributing to outdoor heat dissipation and therefore urban heat island effect. Thus, encouraging more effective natural ventilation to eliminate excessive heat from the indoor environment is critical. Since most of the research focuses on simulation modelling lacking sufficient empirical validation, this paper drawing on field measurement investigates natural ventilation performance in terraced housing with an air well system. More importantly, the key concern as to what extent the current air well system serving as a ventilator is effective to provide better thermal performance in the single storey terraced house is to be addressed. By adopting an existing single storey air welled terrace house, the existing indoor environmental conditions and thermal performance were monitored and measured using scientific equipment, namely HOBO U12 air temperature and air humidity, the HOBO U12 anemometer and the Delta Ohm HD32.3 Wet Bulb Globe Temperature meter for a six-month duration. The findings show that the air temperature of the air well ranged from 27.48°C to 30.92°C, while the mean relative humidity were from 72.67% to 79.25%. The mean air temperature for a test room (single sided ventilation room) ranged from 28.04°C to 30.92°C with a relative humidity of 70.16% to 76%. These empirical findings are of importance, offering novel policy insights and suggestions to potentially revising the existing building code standard and by laws; since the minimum provision of 10% openings has been revealed to be less effective to provide a desired thermal performance and comfort, mandatory compliance with, and the necessity for, the bylaw requirement should be revisited and further studied.

Preprint ARTICLE | doi:10.20944/preprints202102.0358.v1

DM Noise Estimation and DM EMI Filter Design for Interleaved Boost PFC Converters

Naser Nourani Esfetanaj, Huai Wang, Frede Blaabjerg, Pooya Davari

Subject: Engineering, Electrical And Electronic Engineering Keywords: DM Noise Estimation; Interleaved PFC Converters; Phase-Shifting; EMI filter design.

Online: 17 February 2021 (09:52:05 CET)

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Preprint ESSAY | doi:10.20944/preprints201704.0120.v2

Synthesis and Anti-Tumor Activity of Oleanolic Acid Derivatives

Kuai ZhenYu, Lei Li, Shengwen Zhan, Chunlin Li, Yuwei Zhao, Hongrong Chen, Yanqiu Meng

Subject: Chemistry And Materials Science, Medicinal Chemistry Keywords: oleanolic acid derivatives; synthesis; anti-tumor activity; molecular docking; computer-aided drug design

Online: 24 April 2017 (12:08:36 CEST)

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Preprint CONCEPT PAPER | doi:10.20944/preprints201702.0053.v1

Market Spread an Indicator of Systemic Risk in India

Subhash Karmakar, Gautam Bandyopadhyay

Subject: Business, Economics And Management, Finance Keywords: Systemic risk; Systemically Important Firms(SIFs); Stock Price; Stock Price (Close); Stock Price (Open); Stock Price: Bid; Stock Price: Ask; Stock Price: Spread; Joint Probability of Distress(JPoD); Banking Stability Index (BSI); Co-Risk Model

Online: 15 February 2017 (10:40:33 CET)

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Preprint ARTICLE | doi:10.20944/preprints202104.0690.v1

Facade Style Mixing using Artificial Intelligence for Urban Infill

AHMED KHAIRADEEN ALI, One Jae Lee

Subject: Arts And Humanities, Architecture Keywords: : Artificial Intelligence; Generative Adversarial Network; Machine Learning; Computationl Design; Urban infill; Facade design

Online: 26 April 2021 (20:20:29 CEST)

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Preprint ARTICLE | doi:10.20944/preprints201703.0197.v1

Co-integration and Causality Analysis of Carbon Intensity and Coal Consumption of China

Xing Wang, Zhongqi Fan, Ying Zhang

Subject: Engineering, Energy And Fuel Technology Keywords: carbon intensity; coal consumption; co-integration test; Granger causality; error correction model

Online: 27 March 2017 (10:33:34 CEST)

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Preprint ARTICLE | doi:10.20944/preprints201712.0126.v1

Design and Optimization of a MEMS-Based Piezoresistive Accelerometer for Head Injuries Monitoring: A Computational Analysis

Marco Messina, James Njuguna, Chrysovalantis Palas

Subject: Engineering, Mechanical Engineering Keywords: piezoresistive accelerometer; sensor design; biomechanical device; head injuries monitoring; TBI

Online: 18 December 2017 (15:42:12 CET)

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Preprint ARTICLE | doi:10.20944/preprints202002.0234.v1

Sequence Properties of the MAAP Protein and of the VP1 Capsid Protein of Adeno-Associated Viruses

David G. Karlin

Subject: Biology And Life Sciences, Virology Keywords: adeno-associated virus; protein sequence analysis; overlapping genes; amino acid depletion; cysteine depletion; tyrosine depletion; capsid design; membrane-binding amphipathic helix

Online: 17 February 2020 (02:42:39 CET)

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Preprint ARTICLE | doi:10.20944/preprints201705.0094.v1

Fast Preparation of Porous MnO/C Microspheres as Anode Materials for Lithium-Ion Batteries

Jing Su, Hao Liang, Xian-Nian Gong, Xiao-Yan Lv, Yun-Fei Long, Yan-Xuan Wen

Subject: Chemistry And Materials Science, Nanotechnology Keywords: lithium-ion batteries; anode materials; MnO; co-precipitation; T-shaped microchannel reactor

Online: 11 May 2017 (07:49:10 CEST)

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Preprint ARTICLE | doi:10.20944/preprints201704.0014.v1

An Elaborated Study of CO Sensitivities of Cu, Pt and Pd Activated SnO₂ Sensors: Effect of Precipitation Agents, Dopants and Doping Methods

Venkata Krishna Karthik Tangirala, Heberto Gomez-Pozos, Ventura Rodríguez-Lugo, María De La Luz Olvera

Subject: Chemistry And Materials Science, Nanotechnology Keywords: tin oxide pellets; doping; HRTEM analysis; CO; sensitivity

Online: 4 April 2017 (08:16:13 CEST)

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Preprint ARTICLE | doi:10.20944/preprints201706.0004.v1

Implant Stability of Biological Hydroxyapatites Used in Dentistry

María Piedad Ramírez Fernández, Sergio Alexander Gehrke, Patricia Mazón, Jose Luis Calvo-Guirado, Piedad N. De Aza

Subject: Chemistry And Materials Science, Biomaterials Keywords: hydroxyapatite, xenografts; implant design; implant surface

Online: 1 June 2017 (06:19:41 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202305.1449.v2

Analytical and Numerical Investigation of Fatigue Life in Rectangular Plates with Opposite Semicircular Edge Single Notches

Kristaq Hazizi, Mohammad Ghaleeh

Subject: Engineering, Mechanical Engineering Keywords: pressure vessel:; ASME code; optimum design; working pressure; structural analysis; finite element method; autodesk inventor professional

Online: 30 May 2023 (03:04:41 CEST)

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As the demand for liquefied petroleum gas (LPG) continues to increase worldwide, more LPG facilities are being constructed. However, the design and manufacture of pressure vessels used to store dangerous liquids or pressurised fluids, such as LPG, has been a major cause of hazards, including explosions and leakage. In this study, we aim to address this issue by designing and analysing a vertical pressure vessel with a capacity of 10 m3 of pressurised LPG in accordance with the American Society of Mechanical Engineers (ASME) code. Safety is the primary concern in designing pressure vessels due to the potential risks posed by accidents. Therefore, the main objective of this project is to design a pressure vessel that is safe from failure. The vessel is cylindrical with two elliptical heads, two nozzles, a manway and four leg supports, and we used Autodesk Inventor Professional 2023 for geometric modelling and Inventor Nastran for FEA analysis. To investigate the displacements, deflections and Von-Mises stresses in the pressure vessel, we used the finite element method, and Autodesk Inventor Nastran was employed for the analysis. Our results showed that changes to the structure of the pressure vessel were needed to reduce stress in the structure. Specifically, the displacement showed an inverse relationship with the tank section shell thickness. Moreover, we observed that the factor of safety increased linearly with shell thickness. We carefully considered permissible pressures and determined the required wall thickness to ensure acceptable maximum stresses. Our results indicate that the design is safe from failure, and the highest stresses are experienced by the manway followed by the shell, while the heads, nozzles and legs support experienced the lowest stresses. We also performed a theoretical calculation for the entire model and checked the results to ensure they were within the acceptable limits. In summary, our study highlights the importance of designing pressure vessels in accordance with ASME codes to ensure safety and prevent hazards caused by improper design and manufacturing. By using the finite element method, we identified potential stress points in the pressure vessel and were able to make modifications to improve its safety.

Working Paper REVIEW

Web-Based Tools for Computational Enzyme Design

Sérgio M. Marques, Joan Planas-Iglesias, Jiri Damborsky

Subject: Biology And Life Sciences, Biochemistry And Molecular Biology Keywords: web server; rational design; functionalizing enzymes; enzyme discovery; user-friendly tools

Online: 28 January 2021 (07:51:45 CET)

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Preprint ARTICLE | doi:10.20944/preprints201805.0464.v1

Proposal for a Software Sustainability Design Catalogue

Shola Oyedeji, Birgit Penzenstadler, Ahmed Seffah

Subject: Engineering, Control And Systems Engineering Keywords: sustainability; software sustainability; information and communication technology; software design; sustainability requirement; software sustainability analysis; software sustainability guidelines; karlskrona manifesto

Online: 31 May 2018 (09:44:28 CEST)

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Preprint ARTICLE | doi:10.20944/preprints201709.0005.v2

An Application-Oriented Design Method for Networked Driving Simulation

Kareem Abdelgawad, Jürgen Gausemeier, Ansgar Trächtler, Sandra Gausemeier, Roman Dumitrescu, Jan Berssenbrügge, Jörg Stöcklein, Michael Grafe

Subject: Engineering, Automotive Engineering Keywords: autonomous and cooperative vehicle systems; connected driving simulators; systems engineering; system of systems; system-level design; application-oriented development

Online: 12 September 2017 (15:32:19 CEST)

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Preprint ARTICLE | doi:10.20944/preprints201801.0013.v1

Making Less Vulnerable City: Resilience as a New Paradigm of Smart Planning

Francesca Moraci, Maurizio Francesco Errigo, Celestina Fazia, Gianluca Burgio, Sante Foresta

Subject: Arts And Humanities, Architecture Keywords: resilient urban design; smart planning; climate change; resilient regional laws; pleasant public space

Online: 2 January 2018 (12:03:30 CET)

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Working Paper REVIEW

Sequencing Enabling Design and Learning in Synthetic Biology

Pierre-Aurelien Gilliot, Thomas E. Gorochowski

Subject: Biology And Life Sciences, Biology And Biotechnology Keywords: sequencing; omics; synthetic biology; systems biology; machine learning; biological design

Online: 23 April 2020 (03:47:02 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202009.0375.v1

Unexpected Co-infection with Different Strains of SARS-CoV-2 in Patients with COVID-19

Hayder O. Hashim, Mudher K. Mohammed, Mazin J. Mousa, Hadeer H. Abdulameer, Alaa T.S. Alhassnawi, Safa A. Hassan, Mohammed Baqur S. Al-Shuhaib

Subject: Medicine And Pharmacology, Epidemiology And Infectious Diseases Keywords: co-infection; SARS-CoV-2; pike glycoprotein; stop mutations

Online: 17 September 2020 (05:33:59 CEST)

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There is a rising global concern for the ongoing outbreak of SARS-CoV-2 due to its high transmission rate and unavailability of treatment. Through the binding of its spike glycoprotein with angiotensin type 2 (ACE2), SARS-CoV-2 can efficiently get in the cells of patients and start its pandemic cycle. Herein, the biological diversity of SARS-CoV-2 infection was assessed in Babylon province of Iraq by investigating the possible genetic variations of the spike glycoprotein. A specific coding region of 795 bp within the viral spike (S) gene was amplified from 19 patients who suffered from obvious symptoms of SARS-CoV-2 infection. Sequencing results identified fifteen novel nucleic acid variations with a variety of distributions within the investigated samples. The electropherograms of all the identified variations showed obvious co-infections with at least two different viral strains per sample. Within these co-infections, the majority of samples exhibited three nonsense single nucleotide polymorphism (SNP)s, p.301Cdel, p.380Ydel, and p.436del, which yielded three truncated SARS-CoV-2 spike glycoproteins of 301, 380, and 436 amino acids length, respectively. The network and phylogenetic analyses indicated that for all viral infections were derived from multi-ancestral origins. Results inferred from the specific clade-based tree entailed that some viral strains were derived from European G-clade sequences. In conclusion, our data demonstrated the absence of any single strain infection among all investigated viral samples in the studied area, which may entail a higher risk of SARS-CoV-2 in this country. Through the identified high frequency of truncated spike proteins, we suggest that defective SARS-CoV-2 may depend on helper strains having intact spikes in its infection. Alternatively, another putative ACE2-independent route of viral infection way also suggested. To the best of our knowledge, this is the first report to describe the co-infection of multiple strains of SARS-CoV-2 in patients with COVID-19.

Preprint ARTICLE | doi:10.20944/preprints201808.0283.v1

Dimensional Analysis in Power Predicting of a Real Scale Wind Turbine Based on Wind Tunnel Torque Measurement of Small Scaled Models

Sutrisno Sutrisno, Sigit Iswahyudi, Setyawan Wibowo

Subject: Engineering, Mechanical Engineering Keywords: wind tunnel; enlarge design; Buckingham π theorem; torque-diameter correlation; estimated power; field size; 3-D blade; stall delay

Online: 16 August 2018 (12:47:10 CEST)

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Preprint ARTICLE | doi:10.20944/preprints201706.0106.v1

Effect of a Particulate and a Putty-Like Tricalcium Phosphate-Based Bone Grafting Material on Bone Formation, Volume Stability and Osteogenic Marker Expression after Bilateral Sinus Floor Augmentation in Humans

Christine Knabe, Doaa Adel-Khattab, Esther Kluk, Rainer Struck, Michael Stiller

Subject: Chemistry And Materials Science, Biomaterials Keywords: Tricalcium phosphate putty scaffold; bioactive ceramics; bone formation, osteogenesis, osteogenic markers, hard tissue histology; immunohistochemical analysis; split-mouth design; sinus floor augmentation; bone grafting materials

Online: 22 June 2017 (18:33:01 CEST)

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Preprint REVIEW | doi:10.20944/preprints201710.0066.v1

A Review of a Stand-Alone Hydrogen System Application for Private Houses in Greece and the Use of Phase Change Materials in Their Building Construction

Leonidas C. Raptis, Giouli K. Michalakakou, Evangelos I. Gkanas, Sofoklis S. Makridis

Subject: Engineering, Energy And Fuel Technology Keywords: Stand-alone hydrogen systems; Off-grid systems; Hydrogen; Electrolysis; Electrolyzer; Fuel Cell; Phase Change materials (PCM’s); Bioclimatic design

Online: 10 October 2017 (18:10:13 CEST)

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Preprint ARTICLE | doi:10.20944/preprints201812.0299.v1

Efficiency and Effectiveness of the European Parliament under the Ordinary Legislative Procedure

Ani Matei, Cristina Ciora, Reli Ceche, Adrian Stelian Dumitru

Subject: Business, Economics And Management, Business And Management Keywords: European Parliament , Ordinary Legislative Procedure, Co-decision, Efficiency,Effectiveness

Online: 25 December 2018 (08:44:35 CET)

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Preprint ARTICLE | doi:10.20944/preprints201704.0048.v1

Increased Corticospinal Excitability and Muscular Activity in a Lower Limb Reaction Task under Psychological Pressure

Yoshifumi Tanaka, Tatsunori Shimo

Subject: Social Sciences, Behavior Sciences Keywords: stress; transcranial magnetic stimulation; spinal reflex; reaction time; co-contraction

Online: 10 April 2017 (05:59:46 CEST)

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Preprint ARTICLE | doi:10.20944/preprints201802.0044.v1

Optimization of Pump Hydraulic Performance Based on the Response Surface Method

Shengli Xu, Shaowei Zhong, Haixin Zhao

Subject: Engineering, Mechanical Engineering Keywords: pump hydraulic performance; optimization design; response surface method; parameterization; meridional plane

Online: 5 February 2018 (16:05:10 CET)

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Preprint ARTICLE | doi:10.20944/preprints201811.0062.v1

TEG Design for Waste Heat Recovery at an Aviation Jet Engine Nozzle

Pawel Ziolkowski, Knud Zabrocki, Eckhard Müller

Subject: Engineering, Energy And Fuel Technology Keywords: thermoelectric generator, energy conversion, energy harvesting, aviation, jet engine, specific fuel consumption, module design, fill factor, FEM, simulation

Online: 2 November 2018 (13:35:55 CET)

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Preprint ARTICLE | doi:10.20944/preprints202010.0132.v1

pandapipes: an Open Source Piping Grid Calculation Package for the Application in Coupled Multi-Energy Grid Simulations

Daniel Lohmeier, Dennis Cronbach, Simon Ruben Drauz, Martin Braun, Tanja Manuela Kneiske

Subject: Engineering, Energy And Fuel Technology Keywords: sector coupling; gas grid; district heating grid; grid simulation; network analysis; grid operation; open source; multi-energy grids; energy supply; infrastructure design

Online: 6 October 2020 (14:48:08 CEST)

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Preprint ARTICLE | doi:10.20944/preprints201708.0061.v1

Generalized Storage-yield-reliability Relationships for Sizing and Assessing Shopping Centre Rainwater Harvesting Systems in South Africa

John Ndiritu, Guliwe Mondli , Moodley Yashiren

Subject: Engineering, Civil Engineering Keywords: rainwater harvesting; yield, reliability; plotting positions; generalization; optimized hydrologic design; shopping centres

Online: 17 August 2017 (13:53:21 CEST)

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Preprint REVIEW | doi:10.20944/preprints201705.0003.v3

Introducing Sustainability in Value Models to Support Design Decision Making: A Systematic Review

Marco Bertoni

Subject: Engineering, Industrial And Manufacturing Engineering Keywords: sustainability; value modeling; decision support; value driven design; review

Online: 12 June 2017 (13:51:25 CEST)

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Preprint REVIEW | doi:10.20944/preprints202109.0094.v1

Barriers and Challenges Going From Conventional to Cryogenic Superconducting Propulsion for Hybrid and All-Electric Aircrafts

F. Ferreira da Silva, João F. P. Fernandes, P. J. da Costa Branco

Subject: Engineering, Electrical And Electronic Engineering Keywords: Review; Electrical Machines; Superconducting Machines; Hybrid-Electric Aircraft; Propulsion Design; All-Electric Aircraft; Specific Power

Online: 6 September 2021 (13:04:15 CEST)

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Preprint ARTICLE | doi:10.20944/preprints201810.0652.v1

Effects of Supply Chain Design and Collaboration on Customers’ Satisfaction of Instant Noodles in Ekiti State, Nigeria

Oluleye Seun Ogunmola, Kayode Kingsley Arogundade

Subject: Business, Economics And Management, Business And Management Keywords: supply chain management; logistics; collaboration; cooperation; supply chain design; customer satisfaction; distribution; regression; noodles

Online: 29 October 2018 (04:45:36 CET)

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Preprint OPINION | doi:10.3390/sci2030057

Global Significance of Mangrove Blue Carbon in Climate Change Mitigation (Version 1)

Daniel Alongi

Subject: Environmental And Earth Sciences, Environmental Science Keywords: blue carbon; carbon; carbon stock; carbon sequestration; climate change; CO₂ emissions; mangrove; mitigation

Online: 23 July 2020 (00:00:00 CEST)

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Preprint ARTICLE | doi:10.20944/preprints201703.0185.v1

Design, Fabrication and Analysis of Threshold-Value Judging Mechanism in MEMS Safety and Arming Device

Dakui Wang, Wenzhong Lou, Yue Feng, Fufu Wang

Subject: Engineering, Mechanical Engineering Keywords: MEMS S&A device; threshold-value judging mechanism; fabrication process; tensile test; theoretical, simulationand experimentalanalysis; parametric design method

Online: 24 March 2017 (10:12:13 CET)

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Preprint ARTICLE | doi:10.20944/preprints201710.0190.v1

Mast Cells Interact with Endothelial Cells to Accelerate In Vitro Angiogenesis

Devandir Antonio de Souza Junior, Vivian Marino Mazucato, Ana Carolina Santana, Constance Oliver, Maria Celia Jamur

Subject: Biology And Life Sciences, Cell And Developmental Biology Keywords: mast cells; angiogenesis; endothelial cells; tube formation assay; co-culture; gap junction

Online: 31 October 2017 (03:51:50 CET)

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Preprint ARTICLE | doi:10.20944/preprints201710.0010.v1

Thermoelectric Properties of Bi₂Te₃: CuI and the Effect of Its Doping with Pb Atoms

Mi-Kyung Han, Yingshi Jin, Da-Hee Lee, Sung-Jin Kim

Subject: Chemistry And Materials Science, Inorganic And Nuclear Chemistry Keywords: Bi2Te3; Thermoelectric properties; co-doping; n-type

Online: 2 October 2017 (15:33:35 CEST)

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Preprint ARTICLE | doi:10.20944/preprints201806.0155.v1

Quality Assurance Framework Development Based on Six New ECV Data Products to Enhance User Confidence for Climate Applications

Joanne Nightingale, Folkert Boersma, Jan-Peter Muller, Steven Compernolle, Jean-Christopher Lambert, Simon Blessing, Ralf Giering, Nadine Gobron, Isabelle De Smedt, Pierre Coheur, Maya George, Jörg Schulz, Alex Wood

Subject: Environmental And Earth Sciences, Space And Planetary Science Keywords: essential climate variables; climate data records; earth observation satellites; quality assurance; traceability; user requirements; climate applications; surface albedo; LAI; FAPAR; NO2; HCHO; CO

Online: 11 June 2018 (11:24:59 CEST)

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Preprint ARTICLE | doi:10.20944/preprints201810.0019.v1

Benefit-Cost Analysis of Building Information Modeling (BIM) in a Railway Site

Min Ho Shin, Hye Kyung Lee, Hwan Yong Kim

Subject: Engineering, Architecture, Building And Construction Keywords: Building Information Modeling (BIM); Benefit-Cost Analysis (BCA); Railway construction; Liquidated damage; Infrastructure; Planning and design

Online: 1 October 2018 (16:54:20 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202108.0099.v1

Comparative Study of Structural Reliability Assessment Methods for Fixed Offshore Structures

E. Mat Soom, M.K. Abu Husain, N.I. Mohd Zaki, N.A. Mukhlas, S.Z.A. Syed Ahmad, N.U. Azman, Gholamhossein Najafian

Subject: Engineering, Automotive Engineering Keywords: offshore structures; reliability-based design assessment; global ultimate strength assessment; reserve strength ratio; probability of failure

Online: 3 August 2021 (16:19:56 CEST)

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Preprint ARTICLE | doi:10.20944/preprints201807.0629.v1

Designing an Intuitive Driving Experience in a Digital World

Siav-Kuong KUOCH, Christopher Nowakowski, Katharina Hottelart, Patrice Reilhac, Pierre Escrieut

Subject: Engineering, Automotive Engineering Keywords: user experience, UX, user interface, user interaction, automotive cockpit design, intuitive driving, driving automation, digitalization, personalization, Valeo Mobius, Valeo MyMobius.

Online: 31 July 2018 (16:18:10 CEST)

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