ARTICLE
|
doi:10.20944/preprints202212.0512.v1
Subject:
Chemistry And Materials Science,
Physical Chemistry
Keywords:
Intelligent corrosion inhibitor; Oleate imidazoline; Polyacrylamide; pH-controlled release; L80 carbon steel.
Online: 27 December 2022 (07:49:22 CET)
ARTICLE
|
doi:10.20944/preprints202201.0243.v1
Subject:
Chemistry And Materials Science,
Food Chemistry
Keywords:
aqueous micellar system; trypsin inhibitor; isoflavone extraction; non-ionic surfactant; multifactorial optimization
Online: 17 January 2022 (16:01:53 CET)
REVIEW
|
doi:10.20944/preprints202112.0482.v1
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
non-small-cell lung cancer; immune checkpoint inhibitor; Bayesian meta-analysis; Review
Online: 30 December 2021 (12:13:58 CET)
ARTICLE
|
doi:10.20944/preprints202003.0024.v1
Subject:
Medicine And Pharmacology,
Immunology And Allergy
Keywords:
SARS-CoV-2; nonstructural proteins (NSP); NSP12; NSP7; NSP8; virtual screening; inhibitor
Online: 2 March 2020 (03:11:33 CET)
REVIEW
|
doi:10.20944/preprints201807.0254.v1
Subject:
Biology And Life Sciences,
Cell And Developmental Biology
Keywords:
endocrine disruptor, environmental health sciences, gene-environment, inhibitor of differentiation, neurocognitive disorders
Online: 14 July 2018 (23:30:36 CEST)
REVIEW
|
doi:10.20944/preprints201804.0359.v1
Subject:
Biology And Life Sciences,
Immunology And Microbiology
Keywords:
oncolytic virus; in situ autovaccination; cytokine; immune checkpoint inhibitor; immune co-stimulator
Online: 27 April 2018 (09:18:37 CEST)
ARTICLE
|
doi:10.20944/preprints201801.0177.v1
Subject:
Biology And Life Sciences,
Virology
Keywords:
Ebola; influenza virus; HIV; envelope protein; membrane fusion inhibitor; HR2; pentacyclic triterpenoids
Online: 19 January 2018 (04:02:15 CET)
ARTICLE
|
doi:10.20944/preprints202405.1741.v1
Subject:
Neuroscience And Neurology,
Medicine And Pharmacology
Keywords:
Alzheimer’ s disease; vascular complications; monoclonal antibody therapy; Aducanumab; Lecanemab; epoxide of polyunsaturated fatty acid; soluble epoxide hydrolase inhibitor EC5026; EP4 inhibitor; monocyte/macrophage; amyloid-beta degradation
Online: 27 May 2024 (13:00:54 CEST)
ARTICLE
|
doi:10.20944/preprints202403.1760.v1
Subject:
Medicine And Pharmacology,
Pharmacy
Keywords:
JAK-inhibitor; baricitinib; rheumatoid arthritis; real-word data; persistence; adherence; safety; unmet needs.
Online: 28 March 2024 (10:30:28 CET)
REVIEW
|
doi:10.20944/preprints202402.0835.v2
Subject:
Biology And Life Sciences,
Life Sciences
Keywords:
Hypertension; calcium channel blocker; combination therapy; thiazide diuretics; Renin-angiotensin-aldosterone system inhibitor
Online: 16 February 2024 (07:46:23 CET)
ARTICLE
|
doi:10.20944/preprints202312.0595.v1
Subject:
Medicine And Pharmacology,
Hematology
Keywords:
chronic myeloid leukemia; tyrosine kinase inhibitor; very elderly; safety; efficacy; outcome; dose optimization
Online: 8 December 2023 (10:26:16 CET)
ARTICLE
|
doi:10.20944/preprints202212.0023.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
spinal cord injury; X-linked inhibitor of apoptosis protein; neuroprotection; apoptosis; transgenic mice
Online: 1 December 2022 (09:59:17 CET)
ARTICLE
|
doi:10.20944/preprints202208.0208.v1
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
Plasma PD-L1; liquid biopsy; cfRNA; immune checkpoint inhibitor; predictive immune biomarker; NSCLC
Online: 11 August 2022 (06:10:34 CEST)
ARTICLE
|
doi:10.20944/preprints202111.0257.v1
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
metastatic melanoma; targeted therapy; immune checkpoint inhibitor therapy; survival; statutory health insurance data
Online: 15 November 2021 (11:50:07 CET)
COMMUNICATION
|
doi:10.20944/preprints202103.0113.v1
Subject:
Medicine And Pharmacology,
Immunology And Allergy
Keywords:
blood-based mutation burden (bTMB); cancer immunotherapy; immune checkpoint inhibitor (ICI); biomarker; mutation
Online: 2 March 2021 (21:45:40 CET)
REVIEW
Subject:
Chemistry And Materials Science,
Analytical Chemistry
Keywords:
hyperoxaluria; oxalate; inhibitor; small molecule drug; glycolate oxidase; lactate dehydrogenase; liver selective distribution
Online: 31 December 2020 (08:59:47 CET)
ARTICLE
|
doi:10.20944/preprints202007.0581.v1
Subject:
Biology And Life Sciences,
Biology And Biotechnology
Keywords:
Wheat; RNAi silencing; amylase/trypsin inhibitor (ATI); allergy; Non Celiac Wheat Sensitivity (NCWS)
Online: 24 July 2020 (11:51:53 CEST)
ARTICLE
|
doi:10.20944/preprints201810.0570.v1
Subject:
Medicine And Pharmacology,
Pharmacology And Toxicology
Keywords:
bone resorption; butyric acid; HDAC inhibitor; osteoblasts; osteoprotegerin/RANKL; periodontal/root canal pathogens
Online: 24 October 2018 (11:21:42 CEST)
ARTICLE
|
doi:10.20944/preprints201803.0144.v1
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
sea anemone; drug discovery; cancer; antiangiogenic; endothelial cells; RGD motif; Kunitz type inhibitor
Online: 19 March 2018 (08:15:38 CET)
ARTICLE
|
doi:10.20944/preprints202404.1491.v1
Subject:
Virology,
Biology And Life Sciences
Keywords:
HIV-2; integrase strand transfer inhibitor (INSTIs); HIV; integrase; Lenacapavir; SARs-CoV-2
Online: 23 April 2024 (05:06:50 CEST)
ARTICLE
|
doi:10.20944/preprints202404.0994.v1
Subject:
Medicine And Pharmacology,
Clinical Medicine
Keywords:
plasminogen activator inhibitor-1; obstructive sleep apnea; continuous positive airway pressure; atherogenesis; fibrinolytic capacity
Online: 16 April 2024 (07:41:29 CEST)
ARTICLE
|
doi:10.20944/preprints202311.1678.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
erythropoietin; PHD inhibitor; hypoxia; deglycosylation; proximal tubules; distal tubules; renal erythropoietin-producing interstitial cells
Online: 27 November 2023 (08:44:10 CET)
REVIEW
|
doi:10.20944/preprints202209.0296.v1
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
non-small-cell lung cancer; performance status; cytotoxic chemotherapy; immune checkpoint inhibitor; cancer cachexia
Online: 20 September 2022 (05:53:12 CEST)
REVIEW
|
doi:10.20944/preprints202110.0450.v1
Subject:
Medicine And Pharmacology,
Gastroenterology And Hepatology
Keywords:
Fibrosis; Integrin; TGFβ; Therapeutic target; Drug; Inhibitor; Monoclonal antibody; α8β1; α11β1; Hepatic stellate cell
Online: 29 October 2021 (10:16:13 CEST)
ARTICLE
|
doi:10.20944/preprints202108.0366.v2
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
Lung adenocarcinoma; PD-1 inhibitor; LASSO analysis and SVM-RFE; Immune cell infiltration; TCGA
Online: 25 August 2021 (09:22:41 CEST)
REVIEW
|
doi:10.20944/preprints202101.0393.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
Breast cancer; Angiogenesis; Lymphangiogenesis; Cancer Stem cells, microRNA; EP4 receptor; Immune check-point inhibitor
Online: 19 January 2021 (17:40:53 CET)
COMMUNICATION
|
doi:10.20944/preprints201908.0126.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
protein-protein interaction; protein-peptide interaction; triglycine; substrate binding site; peptide; inhibitor; Proteinase K
Online: 11 August 2019 (08:37:08 CEST)
ARTICLE
|
doi:10.20944/preprints201804.0374.v1
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
STAT3 as a drug target; cyclic STAT3 decoy; oligodeoxynucleotide inhibitor; head and neck cancer
Online: 29 April 2018 (10:10:00 CEST)
CONCEPT PAPER
|
doi:10.20944/preprints201804.0358.v1
Subject:
Medicine And Pharmacology,
Pharmacology And Toxicology
Keywords:
snakebite; antidote; inhibitor; small molecule therapeutics; SMT; secretory phospholipase; sPLA2; Neglected Tropical Disease; NTD
Online: 27 April 2018 (09:00:55 CEST)
ARTICLE
|
doi:10.20944/preprints201802.0026.v1
Subject:
Medicine And Pharmacology,
Ophthalmology
Keywords:
pig eye perfusion model; pigmentary glaucoma; ocular hypertension; ocular hypotension; phagocytosis; rho-kinase inhibitor
Online: 5 February 2018 (03:39:57 CET)
ARTICLE
|
doi:10.20944/preprints201710.0180.v1
Subject:
Biology And Life Sciences,
Immunology And Microbiology
Keywords:
primary Sjögren's syndrome; alpha-1-antitrypsin; inhibitor; 4-hydroxy-2-nonenal; autoantibody isotypes; serum
Online: 30 October 2017 (04:30:59 CET)
REVIEW
|
doi:10.20944/preprints202401.1750.v1
Subject:
Biology And Life Sciences,
Life Sciences
Keywords:
ATR; ATR inhibitor; ceralasertib (AZD6738); DNA damage response; immune system; synthetic lethality; ATR-ATM interplay
Online: 24 January 2024 (10:02:52 CET)
ARTICLE
|
doi:10.20944/preprints202401.0336.v1
Subject:
Medicine And Pharmacology,
Urology And Nephrology
Keywords:
circulating tumor cells (CTCs); enzalutamide; bone metastases; castration-resistant prostate cancer; androgen receptor signaling inhibitor
Online: 4 January 2024 (11:29:18 CET)
ARTICLE
|
doi:10.20944/preprints202311.0210.v1
Subject:
Biology And Life Sciences,
Immunology And Microbiology
Keywords:
Brucella abortus; 3-AT; catalase inhibitor; intracellular growth; immune response; RAW 264.7 cell; ICR mouse
Online: 3 November 2023 (05:07:39 CET)
ARTICLE
|
doi:10.20944/preprints202308.0250.v3
Subject:
Biology And Life Sciences,
Life Sciences
Keywords:
PCa; Synthetic lethality; TLK1 signaling; Homologous recombination repair; TLK1 inhibitor J54; CPT-based PCa therapy
Online: 21 September 2023 (08:46:22 CEST)
ARTICLE
|
doi:10.20944/preprints202309.1118.v1
Subject:
Biology And Life Sciences,
Cell And Developmental Biology
Keywords:
epithelial-to-mesenchymal transition; heat shock transcription factor 1; HSF1 inhibitor; human mammary epithelial cells
Online: 18 September 2023 (08:51:33 CEST)
REVIEW
|
doi:10.20944/preprints202307.1897.v1
Subject:
Biology And Life Sciences,
Biology And Biotechnology
Keywords:
Keywords: recurrent glioblastoma; immunotherapy; CAR-T therapy; immune checkpoint inhibitor; cancer vaccine; oncolytic viral therapy
Online: 27 July 2023 (09:30:30 CEST)
ARTICLE
|
doi:10.20944/preprints202104.0456.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
ethidium; tetraphenylphosphonium; multidrug resistance; outer membrane permeability; efflux inhibitor; phenylalanyl-arginyl-β-naphtylamide, Polymyxin B
Online: 18 April 2021 (10:14:56 CEST)
COMMENTARY
|
doi:10.3390/sci2030070
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
small molecule inhibitor; personalized medicine; precision medicine; oncology; targeted therapy; drug delivery; drug screening; chemotherapy
Online: 8 September 2020 (00:00:00 CEST)
REVIEW
|
doi:10.20944/preprints202004.0181.v1
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
renal cell carcinoma; angiogenesis; immune-checkpoint inhibitor; tumor microenvironment; molecular subtypes; prognostic-biomarkers; predictive factors
Online: 12 April 2020 (04:48:44 CEST)
REVIEW
|
doi:10.20944/preprints202402.1049.v1
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
malignant pleural mesothelioma; immune checkpoint inhibitor; orphan drug; good clinical practice; Pharmaceuticals and Medical Devices Agency
Online: 20 February 2024 (04:03:22 CET)
COMMUNICATION
|
doi:10.20944/preprints202305.0704.v2
Subject:
Chemistry And Materials Science,
Other
Keywords:
protein-protein interaction inhibitor; rule of five; rule of four; QEPPI; molecular generation; virtual chemical library
Online: 30 June 2023 (08:50:24 CEST)
ARTICLE
|
doi:10.20944/preprints202306.1387.v1
Subject:
Biology And Life Sciences,
Food Science And Technology
Keywords:
press cake; soy; extrusion; meat analogue; texture; water-holding capacity; oil-binding capacity; trypsin inhibitor activity
Online: 20 June 2023 (07:20:50 CEST)
ARTICLE
|
doi:10.20944/preprints202305.1403.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
Alzheimer’s Disease; Tauopathy; Cell penetrating peptide; Polyarginine; TAT; Liposomes; Nanoparticles; Tau pathology; Tau aggregation inhibitor; Endocytosis
Online: 19 May 2023 (08:06:10 CEST)
ARTICLE
|
doi:10.20944/preprints202111.0447.v1
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
Immunotherapy; immune-checkpoint inhibitor; response prediction; men and women; pembrolizumab; nivolumab; atezolizumab; ECOG; CRP; chemo-immunotherapy
Online: 24 November 2021 (09:02:46 CET)
REVIEW
|
doi:10.20944/preprints202106.0609.v1
Subject:
Medicine And Pharmacology,
Immunology And Allergy
Keywords:
Chronic myeloid leukaemia; chronic phase; Tyrosine kinase inhibitor; Treatment free remission; deep molecular response; BCR-ABL.
Online: 25 June 2021 (08:13:40 CEST)
REVIEW
|
doi:10.20944/preprints202104.0742.v1
Subject:
Medicine And Pharmacology,
Endocrinology And Metabolism
Keywords:
Diabetes mellitus; Glucose metabolism; Histone deacetylase; HDACs; Histone deacetylase inhibitor; HDACi, Insulin release; Sirtuins, Sirtuin activation
Online: 28 April 2021 (10:23:12 CEST)
ARTICLE
|
doi:10.20944/preprints201905.0374.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
Keywords: Tumor microenvironment (TME), glioblastoma multiforme (GBM), GBM- associated macrophages (GAMs), exosomes, oncomiR-21, STAT3 inhibitor.
Online: 31 May 2019 (08:18:33 CEST)
ARTICLE
|
doi:10.20944/preprints202403.1780.v1
Subject:
Biology And Life Sciences,
Aging
Keywords:
cardiovascular dysfunction; metabolic syndrome; renin-angiotensin system; Kallikrein-kinin system; human telomerase reverse transcriptase; complex I inhibitor
Online: 28 March 2024 (14:24:12 CET)
REVIEW
|
doi:10.20944/preprints202311.0836.v1
Subject:
Medicine And Pharmacology,
Cardiac And Cardiovascular Systems
Keywords:
Acute Decompensated Heart failure; fluid overload; loop diuretics; diuretic resistance; mineralocorticoid; SGLT2 inhibitors; ultrafiltration; Carbonic Anhydrase Inhibitor
Online: 14 November 2023 (07:52:29 CET)
ARTICLE
|
doi:10.20944/preprints202308.1201.v1
Subject:
Medicine And Pharmacology,
Pharmacy
Keywords:
Methicillin-resistant Staphylococcus aureus; poly-amidoamine dendrimers (PAMAM); anti-virulence agent, accessory gene regulator; histidine kinase inhibitor.
Online: 16 August 2023 (20:32:54 CEST)
REVIEW
|
doi:10.20944/preprints202106.0176.v1
Subject:
Medicine And Pharmacology,
Gastroenterology And Hepatology
Keywords:
chronic hepatitis B; covalently closed circular DNA; viral integration; transcription factor; nuclear receptor; transcriptional inhibitor; RNA interference
Online: 7 June 2021 (12:43:06 CEST)
ARTICLE
|
doi:10.20944/preprints202104.0732.v1
Subject:
Medicine And Pharmacology,
Immunology And Allergy
Keywords:
Epidermal Growth Factor Receptor (EGFR); mutations, EGFR tyrosine kinase inhibitor; molecular epidemiology; Non-small-cell lung cancer
Online: 28 April 2021 (07:55:22 CEST)
ARTICLE
|
doi:10.20944/preprints202009.0006.v2
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
COVID-19; SARS-CoV-2; protein design; complementarity; competitive inhibitor; homology-based threading in rational protein design
Online: 4 March 2021 (10:14:39 CET)
REVIEW
|
doi:10.20944/preprints202001.0030.v1
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
histone deacetylase 6 inhibitor; personalized treatment; heat shock protein 90α; leukemia stem cells; imatinib resistance; targeted therapy
Online: 4 January 2020 (06:18:22 CET)
REVIEW
|
doi:10.20944/preprints201806.0163.v2
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
SIRT6, Diabetes, Gluconeogenesis, Cancer, Aging, Heart Disease, Pharmacological SIRT6 Inhibitor, Cardiac Hypertrophy, Tumorigenesis, Neurodegeneration, Neurodegenerative Diseases, AD
Online: 29 August 2018 (13:04:23 CEST)
ARTICLE
|
doi:10.20944/preprints201807.0123.v1
Subject:
Biology And Life Sciences,
Virology
Keywords:
Snake venomics; Viperidae; Protobothrops flavoviridis; Habu pit viper; Bottom-Up; Top-Down; BPP; Tripeptide metalloprotease inhibitor; Cytotoxicity
Online: 6 July 2018 (16:34:48 CEST)
TECHNICAL NOTE
|
doi:10.20944/preprints201706.0085.v1
Subject:
Engineering,
Civil Engineering
Keywords:
finite element modeling; electrochemical chloride extraction (ECE); electrical injection of corrosion inhibitor (EICI); rebar corrosion; repair mortar
Online: 19 June 2017 (13:40:09 CEST)
REVIEW
|
doi:10.20944/preprints202401.1219.v1
Subject:
Chemistry And Materials Science,
Nanotechnology
Keywords:
biofuel; insecticides; pesticides; catalytic reduction of CO2; green economy; sustainability; biodegradation; nanoparticles; corrosion inhibitor; nanofertilizer; heavy metal detection
Online: 16 January 2024 (13:35:19 CET)
ARTICLE
|
doi:10.20944/preprints202308.1173.v1
Subject:
Medicine And Pharmacology,
Neuroscience And Neurology
Keywords:
ACEI – Angiotensin converting enzyme inhibitor; HTN - Hypertension; mRS – Modified ranking scale; NIHSS – National institute of health stroke scale
Online: 16 August 2023 (07:09:24 CEST)
ARTICLE
|
doi:10.20944/preprints201608.0211.v1
Subject:
Biology And Life Sciences,
Cell And Developmental Biology
Keywords:
Metalloproteinase; phenanthroline; metalloproteinase inhibitor; zebrafish; aryl hydrocarbon receptor; poly aromatic hydrocarbon toxicity; angiogenesis; neural crest; in vivo study
Online: 26 August 2016 (11:19:51 CEST)
REVIEW
|
doi:10.20944/preprints202310.0910.v1
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
immune checkpoint inhibitor; resistance mechanism; melanoma; oral mucosal melanoma; immunotherapy; immune checkpoint blockade; anti-PD-1; anti-CTLA-4
Online: 17 October 2023 (03:37:34 CEST)
REVIEW
|
doi:10.20944/preprints202107.0353.v1
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
Lung cancer; Adjuvant treatment; Non-small-cell lung carcinoma (NSCLC); Epidermal growth factor receptor (EGFR); Tyrosine kinase inhibitor (TKI)
Online: 15 July 2021 (10:16:30 CEST)
ARTICLE
|
doi:10.20944/preprints202012.0582.v1
Subject:
Medicine And Pharmacology,
Immunology And Allergy
Keywords:
Liquid-based 3D culture; tumoroid; cisplatin resistance; imatinib (gleevec); tyrosine kinase inhibitor (TKI); organoid; spheroid; metastatic colorectal cancer (mCRC)
Online: 23 December 2020 (10:15:46 CET)
ARTICLE
|
doi:10.20944/preprints201903.0166.v1
Subject:
Chemistry And Materials Science,
Medicinal Chemistry
Keywords:
Structure-based design; glycogen phosphorylase inhibitor; glycogen metabolism; type 2 diabetes; X-ray crystallography; N-acyl-β-D-glucopyranosylamine
Online: 15 March 2019 (14:06:06 CET)
ARTICLE
|
doi:10.20944/preprints201710.0127.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
WNT pathway; porcupine inhibitor ETC-1922159; sensitivity analysis; colorectal cancer; unknown biological hypotheses; combinatorial search space; support vector ranking
Online: 18 October 2017 (05:58:17 CEST)
ARTICLE
|
doi:10.20944/preprints202406.0791.v1
Subject:
Biochemistry And Molecular Biology,
Biology And Life Sciences
Keywords:
p-gp; p-glycoprotein; AU1; BPTF inhibitor; triple negative breast cancer; efflux pump; multidrug resistance; multidrug resistance pump; breast cancer
Online: 12 June 2024 (11:58:34 CEST)
ARTICLE
|
doi:10.20944/preprints201909.0124.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
Heat shock factor (HSF-1) knockdown; heat shock proteins 70 and 27; radiosensitization; Hsp90 inhibitor NVP-AUY922; homologous recombination (HR)
Online: 11 September 2019 (13:37:00 CEST)
REVIEW
|
doi:10.20944/preprints202402.1401.v1
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
Biomarker; HCC (Hepatocellular Carcinoma); LC-SPIK (Liver Cancer specific Serine Protease Inhibitor Kazal); AFP (Alpha-Fetoprotein); NAFLD (nonalcoholic fatty liver disease)
Online: 26 February 2024 (12:01:59 CET)
ARTICLE
|
doi:10.20944/preprints202308.0382.v1
Subject:
Medicine And Pharmacology,
Pathology And Pathobiology
Keywords:
pleural mesothelioma; subtypes; immunohistochemistry; Mesothelin; Claudin-15; Complement Factor B (CFB); Plasminogen Activator Inhibitor 1 (PAI1); p21-activated kinase 4 (PAK4).
Online: 4 August 2023 (12:34:31 CEST)
REVIEW
|
doi:10.20944/preprints202205.0037.v1
Subject:
Medicine And Pharmacology,
Dermatology
Keywords:
Melanoma; Chemo-thermo-immuno-therapy; Melanogenesis; Magnetite nanoparticle; Drug delivery system; Heat shock protein; In situ vaccine therapy; Immune checkpoint inhibitor
Online: 5 May 2022 (12:23:27 CEST)
REVIEW
|
doi:10.20944/preprints201707.0019.v1
Subject:
Chemistry And Materials Science,
Medicinal Chemistry
Keywords:
affective disorders; alzheimer’s disease; l-Deprenyl (Selegiline); donepezil; galantamine; value; inhibitor constant; mechanism-based inhibition; multitarget-directed ligand (MTDL); rasagiline; rivastigmine
Online: 11 July 2017 (05:58:53 CEST)
ARTICLE
|
doi:10.20944/preprints202403.0096.v1
Subject:
Medicine And Pharmacology,
Medicine And Pharmacology
Keywords:
Clofazimine; Arbidol; Toremifene; Fusion Inhibitor; Spike-dependent; SARS-CoV-2, S2 segment; S2 subunit; Nsp13 helicase; Surface Plasmon Resonance; Molecular Docking; CHARMM
Online: 4 March 2024 (10:43:07 CET)
ARTICLE
|
doi:10.20944/preprints202111.0229.v1
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
Total metabolic tumor volume; bone marrow to liver ratio; PET/CT; overall survival; immunotherapy; immune checkpoint inhibitor; standardized uptake value; response prediction
Online: 12 November 2021 (14:59:35 CET)
REVIEW
|
doi:10.20944/preprints201811.0179.v1
Subject:
Biology And Life Sciences,
Food Science And Technology
Keywords:
calorie restriction mimetics; anti-aging; lifespan extension; glucose metabolism modulation; chitosan; acarbose; SGLT2 inhibitor; 2-deoxy-D-glucose; D-allulose; D-glucosamine
Online: 7 November 2018 (15:26:42 CET)
REVIEW
|
doi:10.20944/preprints201703.0148.v1
Subject:
Biology And Life Sciences,
Toxicology
Keywords:
microcystin; saxitoxin; cylindrospermopsin; anatoxin-a; anatoxin-a(S); cyanobacteria; organic anion transporting polypeptide; phosphatase inhibitor; acetylcholinesterase; neurotoxicity; water quality; eutrophication; drinking water
Online: 20 March 2017 (06:17:48 CET)
REVIEW
|
doi:10.20944/preprints202007.0314.v1
Subject:
Biology And Life Sciences,
Endocrinology And Metabolism
Keywords:
hepatic fibrosis; Mac-2 binding protein glycated isomer; apoptosis inhibitor of macrophage; patatin-like phospholipase domain-containing protein 3; α-fetoprotein; PIVKA-II
Online: 14 July 2020 (13:55:16 CEST)
ARTICLE
|
doi:10.20944/preprints202001.0122.v1
Subject:
Physical Sciences,
Biophysics
Keywords:
cervical adenocarcinoma; immune-checkpoint inhibitor; programmed cell death-1(PD-1); programmed cell death-ligand 1(PD-L1); CD8 expression; lymphocyte; survival analysis
Online: 12 January 2020 (15:01:23 CET)
ARTICLE
|
doi:10.20944/preprints201711.0008.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
WNT pathway; porcupine inhibitor ETC-1922159; sensitivity analysis; colorectal cancer; unknown biological hypotheses; combinatorial search space; support vector ranking; DNA repair and genomic stability factor RAD51
Online: 1 November 2017 (05:08:04 CET)
REVIEW
|
doi:10.20944/preprints201809.0281.v1
Subject:
Biology And Life Sciences,
Cell And Developmental Biology
Keywords:
axon guidance; growth cone; cytoskeleton; caspases; apoptosis; signal integration; basal level of caspase activity; death associated inhibitor of apoptosis; axon branching; Netrin; DCC; frazzled; slit; robo; Drosophila
Online: 16 September 2018 (09:43:52 CEST)
ARTICLE
|
doi:10.20944/preprints202405.1856.v1
Subject:
Soil Science,
Environmental And Earth Sciences
Keywords:
soil N turnover; straw application; nitrification inhibitor; 15N labeling; 15N recovery; 15N retention; nitrogen use efficiency; Mollisol
Online: 29 May 2024 (04:15:24 CEST)
ARTICLE
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doi:10.20944/preprints202306.0548.v1
Subject:
Medicine And Pharmacology,
Gastroenterology And Hepatology
Keywords:
non-alcoholic steatohepatitis; hepatocellular carcinoma; farnesyltransferase inhibitor; hypoxia-inducible factor-1α; anti-inflammatory response; nuclear factor-κB; transforming growth factor-β; Warburg effect; reactive oxygen species; interleukin-6
Online: 7 June 2023 (12:05:28 CEST)
REVIEW
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doi:10.20944/preprints202302.0123.v1
Subject:
Biology And Life Sciences,
Cell And Developmental Biology
Keywords:
WNT; NF-κB, Ion Channels; Anthrax toxin recep- tors; Poliovirus receptors; Porcupine inhibitor ETC-1922159; Sensitivity analysis; Colorectal cancer; Unknown biological hypotheses; Combinatorial search space; Support vector ranking
Online: 7 February 2023 (06:16:12 CET)
CASE REPORT
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doi:10.20944/preprints201801.0227.v1
Subject:
Medicine And Pharmacology,
Urology And Nephrology
Keywords:
Lactate dehydrogenase (LDH), Computed Tomography (CT), Glomerular filtration rate (GFR), C reactive protein (CRP), Angiotensin converting enzyme inhibitor (ACEI) Angiotensin receptor blocker (ARB), Kidney Urinary bladder ( KUB), Dimercapto Succinic Acid (DMSA)
Online: 24 January 2018 (11:41:15 CET)
ARTICLE
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doi:10.20944/preprints202304.0791.v1
Subject:
Medicine And Pharmacology,
Gastroenterology And Hepatology
Keywords:
Helicobacter pylori-uninfected gastric cancer; gastric adenocarcinoma of foveolar type; raspberry-shaped gastric lesion; gastric adenocarcinoma of fundic-gland type; gastric adenocarcinoma of fundic-gland mucosa type; hyperplastic polyp; proton pump inhibitor-related lesion; early gastric cancer.
Online: 23 April 2023 (08:12:59 CEST)
ARTICLE
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doi:10.20944/preprints201810.0088.v1
Subject:
Chemistry And Materials Science,
Biomaterials
Keywords:
There are many molecules used as drug carrier. TUD-1 is a newly synthesized mesoporous silica (SM) molecule possess two important features; consists of mesoporous so it is very suitable to be drug carrier in addition to that it has the ability to induce apoptosis in cancer cells. However, the effect of TUD-1 appears to act as cell death inducer, regardless of whether it is necrosis or apoptosis. Unfortunately, recent studies indicate that a proportion of cells undergo necrosis rather than apoptosis, which limits the use of TUD-1 as a secure treatment. On the other hand, lithium considered as necrosis inhibitor element. Hence, current study based on the idea of production a new Li/TUD-1 by incorporated mesoporous silica (TUD-1 type) with lithium in order to produce a new compound that has the ability to activate apoptosis by mesoporous silica (TUD-1 type) and at the same time can inhibit the activity of necrosis by lithium. Herein, lithium was incorporated in TUD-1 mesoporous silica by
Online: 4 October 2018 (15:54:02 CEST)