ARTICLE
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
glioma; cancer; carnitine; acylcarnitine; solid-phase microextraction SPME; liquid chromatography-mass spectrometry LC-MS
Online: 2 August 2021 (14:42:36 CEST)
ARTICLE
Subject:
Chemistry And Materials Science,
Analytical Chemistry
Keywords:
Verteporfin; Photosensitizer; Photo Dynamic Therapy; PDT; Photofragments; Photofragmentation channels; Mass Spectrometry; Laser Spectroscopy; Photolysis
Online: 16 October 2020 (14:39:28 CEST)
ARTICLE
|
doi:10.20944/preprints201802.0113.v1
Subject:
Chemistry And Materials Science,
Analytical Chemistry
Keywords:
Bioremediation; gas chromatography; green chemistry; mass spectrometry; microcosm; organotin analysis; static headspace; tributyltin (TBT)
Online: 17 February 2018 (11:39:21 CET)
ARTICLE
|
doi:10.20944/preprints201707.0054.v1
Subject:
Chemistry And Materials Science,
Surfaces, Coatings And Films
Keywords:
Ionic liquids; dicationic; imidazolium; poly(ethylene glycol); tribochemistry; mechanically stimulated gas emission mass-spectrometry
Online: 19 July 2017 (22:59:19 CEST)
ARTICLE
|
doi:10.20944/preprints202401.0973.v1
Subject:
Biology And Life Sciences,
Life Sciences
Keywords:
diabetic kidney disease; effective albumin; reduced albumin; structural alterations; oxidative damages; high resolution mass spectrometry
Online: 12 January 2024 (04:05:34 CET)
ARTICLE
|
doi:10.20944/preprints202312.1493.v1
Subject:
Chemistry And Materials Science,
Analytical Chemistry
Keywords:
mass spectrometry; sphingosine 1-phosphate; dephosphorylation; hydrogen fluoride; multiple reaction monitoring; serum; chronic kidney disease.
Online: 20 December 2023 (09:46:16 CET)
ARTICLE
|
doi:10.20944/preprints202310.0883.v1
Subject:
Public Health And Healthcare,
Public, Environmental And Occupational Health
Keywords:
Antimicrobials; Top Soil Improvers; Reused Waters; High Resolution Mass Spectrometry; Analysis; Hazard Index; Antimicrobial Resistance.
Online: 17 October 2023 (03:34:27 CEST)
ARTICLE
|
doi:10.20944/preprints202310.0532.v1
Subject:
Chemistry And Materials Science,
Analytical Chemistry
Keywords:
solid-phase microextraction; phthalate acid esters; gas chromatography-tandem mass spectrometry; carbon nanotubes hollow microspheres
Online: 10 October 2023 (05:46:35 CEST)
ARTICLE
|
doi:10.20944/preprints202308.1924.v1
Subject:
Environmental And Earth Sciences,
Environmental Science
Keywords:
Bisphenol A (BPA); Bisphenol F (BPF); Bisphenol S (BPS); Liquid-chromatography and tandem mass spectrometry
Online: 29 August 2023 (08:52:24 CEST)
BRIEF REPORT
|
doi:10.20944/preprints202307.0613.v1
Subject:
Biology And Life Sciences,
Virology
Keywords:
COVID19; SARS-CoV-2; Variants of Concern; Diagnosis; LC-MS/MS; Mass-Spectrometry; Spike; Nucleocapsid
Online: 11 July 2023 (03:01:19 CEST)
ARTICLE
|
doi:10.20944/preprints202307.0574.v1
Subject:
Chemistry And Materials Science,
Analytical Chemistry
Keywords:
Filipendula ulmaria; Centrifugal Partition Chromatography; NMR-based dereplication; Liquid Chromatography Mass Spectrometry; Epidermal barrier renewal
Online: 10 July 2023 (08:56:52 CEST)
ARTICLE
|
doi:10.20944/preprints202304.1150.v1
Subject:
Chemistry And Materials Science,
Food Chemistry
Keywords:
promethazine; promethazine sulfoxide; monodesmethyl-promethazine; swine edible tissues; high-performance liquid chromatography-tandem mass spectrometry
Online: 28 April 2023 (08:45:26 CEST)
ARTICLE
|
doi:10.20944/preprints202209.0195.v1
Subject:
Medicine And Pharmacology,
Endocrinology And Metabolism
Keywords:
γ-butyrobetaine; glycemic control; liquid chromatography–mass spectrometry; obesity; trimethylamine N-oxide; type 2 diabetes
Online: 14 September 2022 (08:08:33 CEST)
ARTICLE
Subject:
Medicine And Pharmacology,
Immunology And Allergy
Keywords:
gas chromatography mass spectrometry; metabolomics; acute lymphoblastic leukemia; confocal microscopy; high-throughput drug screens; VAST
Online: 7 June 2021 (08:01:21 CEST)
ARTICLE
|
doi:10.20944/preprints202104.0018.v1
Subject:
Biology And Life Sciences,
Anatomy And Physiology
Keywords:
abiotic stress; acetaldehyde; hexenal; LOX products; mass spectrometry; methanol; proton-transfer reaction; tropical crop species
Online: 1 April 2021 (12:50:17 CEST)
ARTICLE
|
doi:10.20944/preprints202002.0019.v1
Subject:
Biology And Life Sciences,
Endocrinology And Metabolism
Keywords:
metabolomics; LC-MS; mass spectrometry; metabolic profiling; computational; statistical; unsupervised learning; supervised learning; pathway analysis
Online: 3 February 2020 (05:54:14 CET)
ARTICLE
Subject:
Medicine And Pharmacology,
Dietetics And Nutrition
Keywords:
metabolomics; metabolite profiling; prudent diet; western diet; food provisions; diet records; nutritional epidemiology; mass spectrometry
Online: 22 September 2019 (15:20:34 CEST)
ARTICLE
|
doi:10.20944/preprints201808.0349.v1
Subject:
Medicine And Pharmacology,
Pediatrics, Perinatology And Child Health
Keywords:
infant nutrition; breast milk; mammalian milk; formula milk; protein similarity profiling; MALDI-TOF mass spectrometry
Online: 20 August 2018 (10:28:59 CEST)
REVIEW
|
doi:10.20944/preprints202403.1312.v1
Subject:
Medicine And Pharmacology,
Pathology And Pathobiology
Keywords:
Liquid biopsy; clinical oncology; mass spectrometry-based proteomics body fluids; circulating biomarkers; Protein post translational modifications
Online: 26 March 2024 (03:14:14 CET)
ARTICLE
|
doi:10.20944/preprints202402.0886.v1
Subject:
Public Health And Healthcare,
Primary Health Care
Keywords:
tandem mass spectrometry; inborn errors of metabolism; newborn screening; selective screening; scientometrics; bibliometric analysis; visualization; VOSviewer
Online: 16 February 2024 (05:37:53 CET)
ARTICLE
|
doi:10.20944/preprints202305.0349.v1
Subject:
Chemistry And Materials Science,
Physical Chemistry
Keywords:
ionic liquids; imidazolium; hexafluorophosphate; Knudsen effusion mass spectrometry; quantum chemical calculations; thermodynamics; evaporation, decomposition, vapor pressure
Online: 5 May 2023 (10:25:12 CEST)
ARTICLE
|
doi:10.20944/preprints202203.0060.v1
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
carnosine; glioblastoma; fibroblasts; imidazole-containing compounds; cell viability; high per-formance liquid chromatography coupled mass spectrometry
Online: 3 March 2022 (10:31:32 CET)
ARTICLE
|
doi:10.20944/preprints202104.0390.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
redox metabolites; mass-spectrometry method; HILIC chromatography; NADH; NADPH; Glutathione; redox metabolite detection in mammalian cells
Online: 14 April 2021 (16:09:16 CEST)
ARTICLE
|
doi:10.20944/preprints202101.0440.v1
Subject:
Chemistry And Materials Science,
Analytical Chemistry
Keywords:
glycosphingolipids; lipidomics; mass spectrometry; hydrophilic interaction liquid chromatography; human plasma; lipid profile; sample preparation; fragmentation behavior
Online: 22 January 2021 (11:31:39 CET)
ARTICLE
|
doi:10.20944/preprints202002.0088.v1
Subject:
Chemistry And Materials Science,
Analytical Chemistry
Keywords:
structural mass spectrometry; protein structure; chemical cross-linking; disuccinimidyl glutarate; bis(sulfosuccinimidyl) glutarate; bovine serum albumin
Online: 7 February 2020 (02:54:08 CET)
ARTICLE
|
doi:10.20944/preprints202002.0009.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
target identification; drug affinity responsive target stability (DARTS); mass spectrometry imaging (MSI); voacangine; curcumin; natural products
Online: 3 February 2020 (04:36:54 CET)
REVIEW
|
doi:10.20944/preprints202403.0921.v1
Subject:
Chemistry And Materials Science,
Analytical Chemistry
Keywords:
glyphosate; analytical methods; sample preparation; liquid chromatography; gas chromatography; mass spectrometry; cereals; occurrence; accumulation mechanism; regulatory status
Online: 15 March 2024 (12:14:02 CET)
ARTICLE
|
doi:10.20944/preprints202302.0363.v1
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
colorectal cancer; metastasis; tumor heterogeneity; spatial proteomics; mass spectrometry imaging; MALDI imaging; formalin-fixed paraffin-embedded tissues
Online: 21 February 2023 (11:21:41 CET)
ARTICLE
|
doi:10.20944/preprints202206.0244.v1
Subject:
Environmental And Earth Sciences,
Environmental Science
Keywords:
contaminants of emerging concern; bisphenol; microalgae; Phaeodactylum tricornutum; bacteria, extracellular vesicles; electron microscopy; flow cytometry; mass spectrometry
Online: 17 June 2022 (03:57:22 CEST)
ARTICLE
|
doi:10.20944/preprints202008.0623.v1
Subject:
Biology And Life Sciences,
Immunology And Microbiology
Keywords:
Leptospermum scoparium; Cryptomeria japonica; Mānuka; Sugi; Essential oils; Natural products; Secondary metabolites; Antimicrobials; Gas chromatography – Mass spectrometry
Online: 27 August 2020 (14:13:24 CEST)
ARTICLE
|
doi:10.20944/preprints201811.0458.v1
Subject:
Biology And Life Sciences,
Immunology And Microbiology
Keywords:
Bacillus; Bioremediation; Enzymes; Fourier transformed infrared spectroscopy (FTIR); Gas chromatography-mass spectrometry (GC-MS); Physicochemicals; Textile wastewater.
Online: 19 November 2018 (11:19:08 CET)
ARTICLE
|
doi:10.20944/preprints201810.0008.v1
Subject:
Biology And Life Sciences,
Endocrinology And Metabolism
Keywords:
perilipins, milk lipid globules, human breast milk, lipid content, tandem mass spectrometry, ultra-high performance liquid chromatography
Online: 1 October 2018 (12:18:46 CEST)
ARTICLE
|
doi:10.20944/preprints201808.0519.v1
Subject:
Chemistry And Materials Science,
Analytical Chemistry
Keywords:
metabolomics; γ-Hydroxybutyric acid; polyamine profiling analysis, gas chromatography-mass spectrometry; star pattern recognition analysis; multivariate analysis
Online: 30 August 2018 (08:14:55 CEST)
ARTICLE
|
doi:10.20944/preprints202403.1251.v1
Subject:
Biology And Life Sciences,
Food Science And Technology
Keywords:
Nitraria tangutorum Bobrov; Fermentation; Biotransformation; Lactic acid bacteria; High-performance liquid chromatography; mass spectrometry; Phenolic compounds; Anti-diabetic
Online: 21 March 2024 (10:03:25 CET)
ARTICLE
|
doi:10.20944/preprints202102.0494.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
Latent membrane protein 1; Epstein-Barr virus; Herpesvirus; Proteomics; Mass spectrometry; interactions; signaling; extracellular vesicles; exosomes; CD63; Tetraspanin
Online: 22 February 2021 (16:27:27 CET)
ARTICLE
|
doi:10.20944/preprints202008.0282.v1
Subject:
Chemistry And Materials Science,
Analytical Chemistry
Keywords:
cyanobacteria; cyanopeptides; eutrophication; harmful bloom; liquid chromatography tandem mass spectrometry; Global Natural Product Social networking (GNPS); Dereplication strategy.
Online: 12 August 2020 (10:15:46 CEST)
ARTICLE
|
doi:10.20944/preprints202002.0381.v2
Subject:
Medicine And Pharmacology,
Pathology And Pathobiology
Keywords:
SARS-CoV2; corona virus; glycopeptide; N-linked glycans; mass spectrometry; antibody; cryo-EM structure; crystal structures; epitope prediction
Online: 13 April 2020 (11:09:29 CEST)
ARTICLE
|
doi:10.20944/preprints201809.0576.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
almond; thermal/pressure treatment; autoclave; food allergens; high resolution mass spectrometry (HR-MS); immunoreactivity reduction; in vitro digestion
Online: 29 September 2018 (04:23:32 CEST)
COMMUNICATION
|
doi:10.20944/preprints202403.0296.v1
Subject:
Environmental And Earth Sciences,
Other
Keywords:
detection technology of drugs in urban sewage; magnetic solid phase extraction; acoustic ejection mass spectrometry analysis method; fast detection
Online: 6 March 2024 (11:08:13 CET)
ARTICLE
|
doi:10.20944/preprints202401.1773.v1
Subject:
Biology And Life Sciences,
Food Science And Technology
Keywords:
Streptococcus thermophilus; Lactobacillus helveticus; fermented milk; fermentation characteristics; solid-phase microextraction and gas chromatography–mass spectrometry (SPME-GC-MS)
Online: 25 January 2024 (01:49:05 CET)
COMMUNICATION
|
doi:10.20944/preprints202312.2227.v1
Subject:
Chemistry And Materials Science,
Materials Science And Technology
Keywords:
titanium-sponge; structural titanium; pure substance; mass spectrometry with inductively coupled plasma; gamma-spectroscopy with high-purity germanium detectors
Online: 29 December 2023 (02:38:57 CET)
REVIEW
|
doi:10.20944/preprints202306.1651.v1
Subject:
Biology And Life Sciences,
Immunology And Microbiology
Keywords:
Proteomics; ELISA; mass spectrometry; Liquid chromatography; Luminex; Uniprot; Rosseta comment; Mascot; allergy respiratory disease; inflammation type 2; diapedesis; epitopo
Online: 23 June 2023 (09:46:31 CEST)
ARTICLE
|
doi:10.20944/preprints202302.0374.v2
Subject:
Biology And Life Sciences,
Biology And Biotechnology
Keywords:
Carbonaceous chondrite; sample return; amino acid; ultrahigh performance liquid chromatography; Orbitrap-mass spectrometry; organic matter; astrobiology; origin of life
Online: 20 March 2023 (04:36:39 CET)
REVIEW
|
doi:10.20944/preprints202104.0339.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
neurodegeneration, glucose metabolism, enzyme catalysis, protein-protein interaction, hydrogen exchange mass spectrometry, protein cross-linking, protein assembly, molecular modeling
Online: 13 April 2021 (10:19:30 CEST)
ARTICLE
|
doi:10.20944/preprints202405.0131.v1
Subject:
Applied Physics,
Physical Sciences
Keywords:
digital analyser; scintillator; photomultiplier tube (PMT); pulse shape discrimination (PSD); gamma spectrometry; monte Carlo (MC); VR-1 research reactor
Online: 2 May 2024 (10:13:33 CEST)
ARTICLE
|
doi:10.20944/preprints202402.0901.v1
Subject:
Physical Sciences,
Applied Physics
Keywords:
neutron-gamma spectrometry; p-terphenyl scintillator; light output; pulse-shape discrimination (PSD); neutron efficiency; mono-energetic neutrons; digital-signal processing
Online: 16 February 2024 (08:51:51 CET)
ARTICLE
|
doi:10.20944/preprints202401.0367.v1
Subject:
Medicine And Pharmacology,
Epidemiology And Infectious Diseases
Keywords:
Candida albicans; ERG 11; fluconazole resistant; matrix-assisted laser desorption/ionization-time of flight mass spectrometry; MALDI TOF; VITEK 2
Online: 4 January 2024 (07:42:07 CET)
ARTICLE
|
doi:10.20944/preprints202307.1356.v2
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
Bioactive Lipids; Eicosanoids; Fatty Acids; Mass Spectrometry; Lipidomics; Innate Immunity; Type-I Interferon Response; Chronic Myeloid Leukaemia; Cancer Inflammation; Cancer Metabolism
Online: 31 August 2023 (13:17:58 CEST)
COMMUNICATION
|
doi:10.20944/preprints202305.1298.v1
Subject:
Biology And Life Sciences,
Life Sciences
Keywords:
Mass spectrometry; RAS; ACE; ACE2; CPN; bradykinin; hypertension; cardiovascular disease; antihypertensiva; ACE inhibitors; angiotensin receptor blockers; bradykinin; neuropeptide re-porter assay
Online: 18 May 2023 (08:13:10 CEST)
ARTICLE
|
doi:10.20944/preprints201907.0263.v1
Subject:
Chemistry And Materials Science,
Analytical Chemistry
Keywords:
ambient ionization; mass spectrometry; high-throughput sampling; imaging; modular robot; open hardware; lab automation; peer production; open software; low-temperature plasma
Online: 23 July 2019 (15:20:38 CEST)
ARTICLE
|
doi:10.20944/preprints201705.0132.v1
Subject:
Biology And Life Sciences,
Plant Sciences
Keywords:
Pittosporum tobira (Thunb.) Aiton; Essential oils (EOs); Headspace solid-phase microextraction (HS-SPME); Gas chromatography-mass spectrometry (GC-MS); Anticancer activity
Online: 17 May 2017 (13:08:12 CEST)
ARTICLE
|
doi:10.20944/preprints202311.0727.v1
Subject:
Medicine And Pharmacology,
Pediatrics, Perinatology And Child Health
Keywords:
newborn screening; lysosomal storage disease; Pompe disease; Mucopolysaccharidosis type I; Gaucher disease; Fabry disease; second tier test; tandem mass spectrometry; glycosaminoglycans; lysosphingosine.
Online: 10 November 2023 (16:19:05 CET)
ARTICLE
Subject:
Chemistry And Materials Science,
Analytical Chemistry
Keywords:
17α-methyl steroids; long-term metabolites; gas chromatography-mass spectrometry; 17-hydroxymethyl-17-methyl-18-nor; D-ring alteration; doping control; metabolism
Online: 1 March 2021 (13:19:54 CET)
ARTICLE
|
doi:10.20944/preprints202402.0941.v1
Subject:
Medicine And Pharmacology,
Medicine And Pharmacology
Keywords:
Liquid chromatography/tandem mass spectrometry (LC/MS/Inductively coupled plasma mass spectrometer (ICP-MS); Bat feces; Luminous sand; Visual deterioration; Vitamins; Heavy metals
Online: 19 February 2024 (11:31:34 CET)
ARTICLE
|
doi:10.20944/preprints202011.0305.v1
Subject:
Chemistry And Materials Science,
Analytical Chemistry
Keywords:
Leucophyllum frutescens; Total Phenolic Contents (TPC); Total Flavonoid Content (TFC); Total Antioxidant Activity (TAA); DPPH; CUPRAC; FRAP; gas chromatography-mass spectrometry (GC-MS)
Online: 10 November 2020 (12:00:06 CET)
ARTICLE
|
doi:10.20944/preprints202308.1675.v1
Subject:
Chemistry And Materials Science,
Analytical Chemistry
Keywords:
Matrix-assisted laser desorption/ionization time-of-flight mass spectrometry; gold nanoshell; nanogap; surface-assisted laser desorption/ionization; silica core nanoparticle; small-molecule analysis
Online: 24 August 2023 (03:40:39 CEST)
ARTICLE
|
doi:10.20944/preprints202111.0414.v1
Subject:
Biology And Life Sciences,
Anatomy And Physiology
Keywords:
endoplasmic reticulum; lipid droplets; peroxisomes; PEX3; protein targeting; membrane protein insertion; protein translocation; label-free quantitative mass spectrometry; differential protein abundance analysis; Zellweger syndrome
Online: 23 November 2021 (09:23:16 CET)
ARTICLE
Subject:
Chemistry And Materials Science,
Analytical Chemistry
Keywords:
gold nanoparticles; theranostics; in vivo computed tomography imaging; non-small cell lung cancer; in vivo biodistribution; surface passivation; inductively coupled plasma optical emission spectrometry
Online: 30 December 2020 (12:28:43 CET)
ARTICLE
Subject:
Chemistry And Materials Science,
Analytical Chemistry
Keywords:
glycolipidomics; GIPC; glycosyl inositol phospho ceramides; Lipid Data Analyzer; lipidomics; sphingolipids; ultra-high pressure liquid chromatography; high-resolution mass spectrometry; LC-MS; automated annotation
Online: 8 September 2020 (12:34:56 CEST)
Subject:
Chemistry And Materials Science,
Analytical Chemistry
Keywords:
gastrodia tuder halimasch powder; ultra high performance liquid chromatography tan- 34 dem quadrupole electrostatic field orbitrap high resolution mass spectrometry; stoichiometry; fer- 35 mentation processing
Online: 8 September 2023 (12:39:53 CEST)
ARTICLE
|
doi:10.20944/preprints202308.0182.v1
Subject:
Biology And Life Sciences,
Food Science And Technology
Keywords:
Beetroot (Beta vulgaris); Total Correlation Spectroscopy (TOCSY); Gas Chromatog-raphy-Mass Spectrometry (GC-MS); selective TOCSY; Homonuclear single quantum correlation (HSQC); fatty acid methyl esters (FAME)
Online: 2 August 2023 (10:01:22 CEST)
REVIEW
|
doi:10.20944/preprints202305.0503.v1
Subject:
Biology And Life Sciences,
Biophysics
Keywords:
RNP assembly; ribosome assembly; protein-RNA interactions; RNA folding; assembly intermediates; in vitro reconstitutions; mass spectrometry; single-molecule fluorescence microscopy; cryo-electron microscopy; RNA structure probing
Online: 8 May 2023 (10:01:55 CEST)
ARTICLE
|
doi:10.20944/preprints201905.0189.v1
Subject:
Chemistry And Materials Science,
Analytical Chemistry
Keywords:
exhaled breath analysis; field-asymmetric ion mobility spectrometry; FAIMS; Fourier-transform infrared spectroscopy; FTIR; luminescence sensing; infrared sensors; hyphenated techniques; hybrid techniques; acetone; carbon dioxide; oxygen
Online: 15 May 2019 (10:49:38 CEST)
ARTICLE
|
doi:10.20944/preprints202203.0143.v1
Subject:
Biology And Life Sciences,
Cell And Developmental Biology
Keywords:
human pluripotent stem cells; human embryonic stem cells; human induced pluripotent stem cells; cellular metabolism; oxygen; self-renewal; pluripotency; differentiation; volatile organic compounds; Selected ion flow tube-mass spectrometry
Online: 10 March 2022 (10:23:46 CET)
ARTICLE
|
doi:10.20944/preprints202001.0139.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
bacteria; barium monocarboxylates; chemical deposition techniques; free fatty acids (FFAs); Langmuir film technology; matrix-assisted laser desorption/ionization-time of flight mass spectrometry (MALDI-TOF-MS); metabolic fingerprinting; rhizobia
Online: 13 January 2020 (13:25:49 CET)
ARTICLE
|
doi:10.20944/preprints201911.0042.v1
Subject:
Biology And Life Sciences,
Endocrinology And Metabolism
Keywords:
olivo-ponto-cerebellar atrophy (OPCA); amyotrophic lateral sclerosis (ALS); tauopathy; leukodystrophy; mass spectrometry; RT-qPCR; Ceramide Synthase (CERS2/CERS1); Serine Palmitoyltransferase 2 (Sptlc2); neutral Sphingomyelinase (Smpd3); neutral Ceramidase (Asah2); Fatty Acid Elongase (Elovl1/4/5); SCA34; SCA38; acid Sphingomyelinase (ASMase, Smpd1)
Online: 5 November 2019 (03:04:02 CET)