COMMUNICATION
|
doi:10.20944/preprints202401.0934.v1
Subject:
Medicine And Pharmacology,
Pathology And Pathobiology
Keywords:
Breast Cancer; Immunohistochemistry; ER; PR; HER-2; Ki-67; APIS; mRNA Expression Testing
Online: 12 January 2024 (02:38:53 CET)
ARTICLE
|
doi:10.20944/preprints202306.0015.v1
Subject:
Medicine And Pharmacology,
Epidemiology And Infectious Diseases
Keywords:
COVID-19; mRNA-based vaccine; safety; multiple sclerosis; AEFI; observational study; three doses
Online: 1 June 2023 (03:37:57 CEST)
ARTICLE
|
doi:10.20944/preprints202305.2084.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
urinary extracellular vesicles,; exosomes; urine; diabetic kidney disease; reference genes; miRNA; mRNA; sequencing
Online: 30 May 2023 (08:23:23 CEST)
HYPOTHESIS
|
doi:10.20944/preprints202303.0441.v1
Subject:
Medicine And Pharmacology,
Pulmonary And Respiratory Medicine
Keywords:
IgG4 antibodies; mRNA vaccines; immuno-tolerance; auto-immunity; SARS-CoV-2; COVID-19.
Online: 27 March 2023 (03:56:26 CEST)
REVIEW
|
doi:10.20944/preprints202301.0133.v2
Subject:
Biology And Life Sciences,
Immunology And Microbiology
Keywords:
COVID-19 vaccination; mRNA vaccines; Clinical Trials; Safety Assessment; Novel Technologies; Spike protein
Online: 12 January 2023 (03:16:56 CET)
ARTICLE
|
doi:10.20944/preprints202208.0151.v1
Subject:
Medicine And Pharmacology,
Cardiac And Cardiovascular Systems
Keywords:
BNT162b2 mRNA COVID-19 vaccine; COVID-19 vaccine; cardiovascular effects; myocarditis; adolescents; Thailand
Online: 8 August 2022 (10:40:23 CEST)
ARTICLE
|
doi:10.20944/preprints202111.0013.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
Nonsense-mediated mRNA Decay; UPF3B-knockout; RNA-Sequencing; Intellectual disability; Neuro-developmental disorders
Online: 1 November 2021 (12:17:15 CET)
REVIEW
|
doi:10.20944/preprints202107.0402.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
synthetic mRNA; analogue caps; elF4E; mTORC1; autophagy: immunity deregulation; maturation defects; autoimmunity; cancer
Online: 19 July 2021 (10:41:42 CEST)
ARTICLE
|
doi:10.20944/preprints202307.1142.v1
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
cervical cancer; fig latex; ficus carica; RNA-seq; pathway enrichment; high risk HPV; antigen presentation; antigen processing
Online: 18 July 2023 (13:28:03 CEST)
REVIEW
|
doi:10.20944/preprints202304.1239.v1
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
Cervical cancer; Human papillomavirus (HPV); Photodynamic therapy (PDT); Squamous in-traepithelial neoplasia; Bibliometric analysis; Molecular Docking; Fullerene
Online: 30 April 2023 (02:31:30 CEST)
REVIEW
|
doi:10.20944/preprints202104.0602.v2
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
cancer; DNA sequencing; DNA synthesis; enzyme; free-radicals; genome; HPV; oncogenes; retinoblastoma; ribonucleotide reductase; RnR; SMT; TCGA
Online: 6 July 2021 (11:32:47 CEST)
REVIEW
|
doi:10.20944/preprints202002.0007.v1
Subject:
Biology And Life Sciences,
Virology
Keywords:
molecular diagnostics; molecular epidemiology; HIV; HBV; HCV; HPV; Zika virus; Dengue virus; tuberculosis; SARS; MERS; nCov-2019
Online: 3 February 2020 (03:47:27 CET)
CASE REPORT
|
doi:10.20944/preprints202403.1661.v2
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
COVID-19 genetic vaccines; mRNA vaccines; adverse effects; lymphoblastic leukemia; lymphoblastic lymphoma
Online: 1 April 2024 (13:21:50 CEST)
ARTICLE
|
doi:10.20944/preprints202402.1734.v1
Subject:
Medicine And Pharmacology,
Neuroscience And Neurology
Keywords:
Neurodegenerative diseases; Alzheimer’s disease; mRNA vaccine; antibody targeting; chemical targeting; blood-brain barrier; nanobodies.
Online: 29 February 2024 (12:55:04 CET)
REVIEW
|
doi:10.20944/preprints202311.1883.v1
Subject:
Medicine And Pharmacology,
Cardiac And Cardiovascular Systems
Keywords:
COVID-19 vaccines; mRNA vaccine; SARS-CoV-2 spike; myocarditis; ACE2; renin-angiotensin system
Online: 29 November 2023 (12:20:42 CET)
ARTICLE
|
doi:10.20944/preprints202206.0116.v1
Subject:
Medicine And Pharmacology,
Pulmonary And Respiratory Medicine
Keywords:
SARS-CoV2; inactivated vaccine; mRNA vaccine; COVID-19; homologous vaccination; heterolo-gous vaccination; protectivity
Online: 8 June 2022 (05:39:30 CEST)
REVIEW
|
doi:10.20944/preprints202206.0229.v1
Subject:
Biology And Life Sciences,
Immunology And Microbiology
Keywords:
pharynx; oncogenic virus; oropharyngeal cancer; nasopharyngeal cancer; human papillomavirus (HPV); Epstein–Barr virus (EBV); microbiome; infection; inflammation; carcinogenesis
Online: 16 June 2022 (04:27:04 CEST)
ARTICLE
|
doi:10.20944/preprints202311.0182.v1
Subject:
Public Health And Healthcare,
Public Health And Health Services
Keywords:
Abdominal obesity, obesity, BMI, BNT162b2 mRNA vaccine, antibody response, IgG-TrimericS, booster dose, COVID-19
Online: 2 November 2023 (14:42:21 CET)
HYPOTHESIS
|
doi:10.20944/preprints202308.1130.v1
Subject:
Medicine And Pharmacology,
Immunology And Allergy
Keywords:
COVID-19; SARS-CoV-2; ZIKV; mRNA; RNAi; ncRNA; L1; retrotransposons; pluripotent multipotent stem cells
Online: 15 August 2023 (12:42:29 CEST)
REVIEW
|
doi:10.20944/preprints202307.1409.v1
Subject:
Biology And Life Sciences,
Life Sciences
Keywords:
spinal and bulbar muscular atrophy; antisense therapy; oligonucleotide; splice switching; mRNA knockdown; androgen receptor; AR45
Online: 20 July 2023 (09:53:18 CEST)
REVIEW
|
doi:10.20944/preprints202307.1341.v1
Subject:
Biology And Life Sciences,
Biology And Biotechnology
Keywords:
vaccine adaption; product life cycle; nanocarrier; mRNA vaccines; vaccine market; protein structure prediction; digital twin
Online: 20 July 2023 (02:34:07 CEST)
ARTICLE
|
doi:10.20944/preprints202109.0431.v1
Subject:
Medicine And Pharmacology,
Pharmacology And Toxicology
Keywords:
C. roseus; HepG2; silver nanoparticles; AgNPs; mRNA; transcriptomic; gene expression; oxidative stress; apoptosis; cell cycle.
Online: 24 September 2021 (12:44:00 CEST)
REVIEW
|
doi:10.20944/preprints202106.0725.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
mRNA vaccine; viral vector vaccine; Spike protein; antigen presentation; polyethylene glycol; platelet factor 4; thrombosis
Online: 30 June 2021 (09:46:15 CEST)
REVIEW
|
doi:10.20944/preprints202106.0541.v1
Subject:
Biology And Life Sciences,
Anatomy And Physiology
Keywords:
cardiac arrhythmias; atrial fibrillation; PITX2; computational model; electrical remodelling; structural remodelling; calcium handling; mRNA; electrophysiology
Online: 22 June 2021 (12:32:52 CEST)
REVIEW
|
doi:10.20944/preprints202401.0786.v1
Subject:
Medicine And Pharmacology,
Obstetrics And Gynaecology
Keywords:
cervical cancer; high-risk human papillomavirus; cervical intraepithelial neoplasia; Papanicolaou test; p16/Ki-67 dual staining; cytology; HPV testing
Online: 10 January 2024 (11:07:58 CET)
REVIEW
|
doi:10.20944/preprints202310.0947.v1
Subject:
Medicine And Pharmacology,
Pathology And Pathobiology
Keywords:
alternative mRNA splicing; amino acids; inflammation; dyslipidemia; macrophages; NAFLD; NASH; regulatory T cells; vascular endothelial cells
Online: 17 October 2023 (03:30:33 CEST)
ARTICLE
|
doi:10.20944/preprints202310.0305.v1
Subject:
Medicine And Pharmacology,
Other
Keywords:
HIV-1 infection; SARS-CoV-2 infection; Neutralizing antibodies; mRNA Vaccines; T-cell immunity; Immunity waning
Online: 6 October 2023 (05:08:35 CEST)
ARTICLE
|
doi:10.20944/preprints202308.2202.v1
Subject:
Biology And Life Sciences,
Insect Science
Keywords:
Insect transgenesis; Aedes; Drosophila suzukii; tephritids; transformation efficiency; recombination efficiency; piggyBac transposase; helper plasmid; capped mRNA
Online: 1 September 2023 (14:00:54 CEST)
REVIEW
|
doi:10.20944/preprints202001.0203.v1
Subject:
Biology And Life Sciences,
Immunology And Microbiology
Keywords:
immunoglobulin (Ig); nonsense-mediated mRNA decay (NMD); nonsense-associated altered splicing (NAS); B lymphocytes; plasma cells
Online: 18 January 2020 (10:21:18 CET)
ARTICLE
|
doi:10.20944/preprints202403.1035.v1
Subject:
Medicine And Pharmacology,
Immunology And Allergy
Keywords:
HIV-1 1; HIV-2 2; surface proteins 3; Nef proteins 4; mRNA delivery 5; Universal vaccine.
Online: 18 March 2024 (11:24:43 CET)
REVIEW
|
doi:10.20944/preprints202201.0372.v1
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
gene therapy; non-viral vectors; gene delivery; cancer; nucleic acid delivery; nanoparticles; lipids; lipid nanoparticles; mRNA; siRNA
Online: 25 January 2022 (09:01:41 CET)
ARTICLE
|
doi:10.20944/preprints202012.0287.v2
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
ABCB1; bortezomib; CXCR4; gene expression; MAF; MARCKS; multiple myeloma; mRNA; POMP; PSMB5; refractory; RPL5; TXN; XBP1; sensitive
Online: 25 January 2021 (13:17:31 CET)
REVIEW
|
doi:10.20944/preprints202009.0162.v2
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
amyloids; frozen accident; genetic code; hydrogels; liquid-liquid phase separation; mRNA; polyglycine; rRNA; ribosomes; translational fidelity; tRNA
Online: 21 October 2020 (10:48:18 CEST)
REVIEW
|
doi:10.20944/preprints202007.0466.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
Alternative Splicing; RNA-Seq; Machine Learning; Deep Learning; Recommender Systems; Multiple Instance Learning; mRNA Isoforms; Gene Ontology
Online: 20 July 2020 (10:53:23 CEST)
ARTICLE
|
doi:10.20944/preprints202308.1597.v1
Subject:
Biology And Life Sciences,
Biophysics
Keywords:
membraneless organelles; mRNA; HILO microscopy; liquid-liquid phase separation; biomolecular condensates; RNP granules; colocalization; intermolecular interactions; Donnan potential
Online: 22 August 2023 (16:35:13 CEST)
REVIEW
|
doi:10.20944/preprints202302.0429.v1
Subject:
Medicine And Pharmacology,
Dermatology
Keywords:
RNA therapeutics; skin; mRNA therapeutics; siRNA therapeutics; antisense oligonucleotide ther-apeutics; ASO; melanoma; hypertrophic scars; wound healing; dermatology
Online: 27 February 2023 (01:53:06 CET)
REVIEW
|
doi:10.20944/preprints201901.0081.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
gene regulation; translation; mRNA; IRES; ITAF; hnRNP; chaperone; stress; nucleocytoplasmic translocation; ribosome; lncRNA; translation initiation factor; P-bodies
Online: 9 January 2019 (08:49:45 CET)
ARTICLE
|
doi:10.20944/preprints202302.0278.v1
Subject:
Biology And Life Sciences,
Virology
Keywords:
COVID-19; SARS-CoV-2; vaccine; mRNA vaccine; adenoviral vector vaccine; adverse event; local adverse event; systemic adverse event
Online: 16 February 2023 (08:00:51 CET)
ARTICLE
|
doi:10.20944/preprints202401.0101.v1
Subject:
Medicine And Pharmacology,
Immunology And Allergy
Keywords:
COVID-19 Booster Vaccination; Adverse Events; Vaccine Safety; Immunization Strategies; Pharmacovigilance; mRNA Vaccines; Taiwan's Vaccination Program; Real-World Evidence
Online: 3 January 2024 (02:38:46 CET)
REVIEW
|
doi:10.20944/preprints202303.0464.v1
Subject:
Medicine And Pharmacology,
Pharmacology And Toxicology
Keywords:
Therapeutic proteins; Recombinant proteins; Repurposing; Reinventing, Drug-antibody combinations, AI/ML, Efficacy improvement, Immunogenicity; Artificial Intelligence; mRNA; High throughput analysis
Online: 27 March 2023 (14:02:03 CEST)
CONCEPT PAPER
|
doi:10.20944/preprints202009.0723.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
Glycogen Storage Disease Type 1a, Glucose-6-phosphatase Catalytic Subunit (G6PC), Glucose-6-phosphatase (G6Pase), prime editing, mRNA delivery, CRISPR
Online: 30 September 2020 (08:05:17 CEST)
ARTICLE
|
doi:10.20944/preprints202103.0777.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
Exosomal PD-L1 mRNA; extracellular vesicles; Triple Negative Breast Cancer; Immunotherapy; PD-L1 axis; Atezolizumab – nab-paclitaxel; Predictive biomarkers; Liquid biopsy
Online: 31 March 2021 (15:27:45 CEST)
ARTICLE
|
doi:10.20944/preprints202401.1673.v1
Subject:
Medicine And Pharmacology,
Epidemiology And Infectious Diseases
Keywords:
COVID-19; SARS-CoV-2; nucleoside-modified mRNA (modRNA); vaccination; Vaccine-induced Immune Thrombotic Thrombocytopenia (VITT); immunosenescence; inflammaging; older adults; lockdown; Italy
Online: 23 January 2024 (08:28:50 CET)
ARTICLE
|
doi:10.20944/preprints202001.0051.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
deadenylation; DNA damage response; ER-anchored ribonuclease; ER-associated mRNAs; mRNA decay; poly(A) length profile; poly(A)-specific ribonuclease; translation efficiency
Online: 6 January 2020 (02:48:23 CET)
REVIEW
|
doi:10.20944/preprints202307.1198.v1
Subject:
Medicine And Pharmacology,
Cardiac And Cardiovascular Systems
Keywords:
myocarditis; sudden death; chest pain; autopsy; necropsy; COVID-19; COVID-19 vaccines; mRNA; SARS-CoV-2 vaccination; death; excess mortality; spike protein; organ system
Online: 18 July 2023 (09:34:51 CEST)
ARTICLE
|
doi:10.20944/preprints202208.0463.v1
Subject:
Medicine And Pharmacology,
Immunology And Allergy
Keywords:
COVID-19 vaccines; vaccine effectiveness; BNT162b2 vaccine; mRNA-1273 vaccine; ChAdOx1 vaccine; 19 Elecsys Anti-SARS-CoV-2 S assay; reactogenicity; vaccine-associated symptoms
Online: 26 August 2022 (14:14:39 CEST)
REVIEW
|
doi:10.20944/preprints202106.0377.v2
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
aa = amino acids; ACE-2 = receptor angiotensin-converting enzyme 2; cDNA = complementary DNA; mRNA = messenger RNA; orf = open reading frame; RBD = receptor binding protein; S-protein = Spike protein; SARS-CoV-2 = severe respiratory syndrome coronavirus 2; Vaccines.
Online: 22 June 2021 (11:53:34 CEST)
ARTICLE
|
doi:10.20944/preprints201902.0172.v4
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
RNA-dependent amplification of mammalian mRNA; physiologically occurring intracellular PCR, iPCR; RNA-dependent RNA polymerase, RdRp; chimeric RNA; sense-strand RNA; antisense-strand RNA
Online: 12 June 2019 (12:21:59 CEST)
ARTICLE
|
doi:10.20944/preprints202310.1811.v1
Subject:
Medicine And Pharmacology,
Obstetrics And Gynaecology
Keywords:
Cervical cancer; HPV screening; Prevention strategies; Human Papillomavirus; HIV interaction; "Test and Treat" approach; Number Needed to Treat; Positive Predictive Value; Negative Predictive Value; Risk management; Global health challenges
Online: 27 October 2023 (13:21:23 CEST)
REVIEW
|
doi:10.20944/preprints202309.1385.v1
Subject:
Biology And Life Sciences,
Food Science And Technology
Keywords:
Lutein; post-COVID syndrome; mRNA vaccination injury syndrome; inflammatory response; reactive oxygen species; reactive nitrogen species; arrhythmogenic heart phenotype; antioxidant defense; bioavailability; extra virgin olive oil
Online: 20 September 2023 (10:07:58 CEST)
ARTICLE
|
doi:10.20944/preprints202307.1768.v1
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
social and global inequities; access to health programs; cervical cancer screening program; HPV vaccination programs; knowledge, believes, acceptance of vaccines/ screening; participation in screening programs; incidence and mortality rates for cervical cancer; pelvectomies
Online: 26 July 2023 (07:19:17 CEST)
REVIEW
|
doi:10.20944/preprints202312.0185.v1
Subject:
Medicine And Pharmacology,
Immunology And Allergy
Keywords:
ADE, HERV-K102, HERV-K HML-2, immunosenescence, foamy macrophages, virus-anti-virus, pandemic preparedness, mRNA COVID-19 vaccines, alpha-fetoprotein antagonists, virus strategies, anti-viral, trained (innate) immunity
Online: 4 December 2023 (10:53:40 CET)
ARTICLE
|
doi:10.20944/preprints202307.1155.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
miRNA; piRNA; mRNA; CA125; progesterone receptor (PGR); new-generation sequencing (NGS); quantitative RT-PCR; serous ovarian carcinoma; borderline cystadenoma; benign cystadenoma; formalin-fixed paraffin-embedded (FFPE) blocks; blood plasma; cytoreduction
Online: 18 July 2023 (09:58:12 CEST)
REVIEW
|
doi:10.20944/preprints202209.0482.v1
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
Telomerase reverse transcriptase; TERT; TERT promoter; TERTp; human papillomavirus; HPV; Epstein Barr virus (EBV); Kaposi sarcoma-associated herpesvirus; HHV-8; hepatitis B virus; HBV; hepatitis C virus; HCV; human T-cell leukemia virus-1; HTLV-1
Online: 30 September 2022 (10:11:58 CEST)