ARTICLE
|
doi:10.20944/preprints202007.0424.v1
Subject:
Chemistry And Materials Science,
Medicinal Chemistry
Keywords:
4-Phenylbutyric acid; Colon-targeted drug delivery; Colitis; Prodrug; ER stress; Chemical chaperone
Online: 19 July 2020 (19:15:20 CEST)
ARTICLE
|
doi:10.20944/preprints202310.1260.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
Protons; X-rays; oral squamous cell carcinoma; extracellular vesicles; non-targeted effects of radiation
Online: 19 October 2023 (09:59:48 CEST)
ARTICLE
|
doi:10.20944/preprints202307.0262.v1
Subject:
Medicine And Pharmacology,
Pharmacology And Toxicology
Keywords:
DCL ligand; iodine radioisotopes; radiolabeled pharmaceuticals; targeted delivery; prostatic specific membrane antigen; prostate cancer
Online: 5 July 2023 (04:43:46 CEST)
ARTICLE
|
doi:10.20944/preprints202303.0315.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
Type I nitroreductase; NfsB; Crystal structure; Prodrug; Metronidazole; Targeted cellular ablation; Tinidazole; CB1954; Dinitrotoluene
Online: 17 March 2023 (03:22:59 CET)
ARTICLE
|
doi:10.20944/preprints202212.0214.v1
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
Breast; Targeted Radiotherapy; Lung injury; Heart injuries; Health-Related Quality Of Life; Irradiation toxicity.
Online: 13 December 2022 (01:17:52 CET)
COMMUNICATION
|
doi:10.20944/preprints202112.0420.v3
Subject:
Chemistry And Materials Science,
Analytical Chemistry
Keywords:
Non-targeted methods; method validation; food fraud; food authenticity; mass spectrometry; spectroscopy; NGS; NMR
Online: 23 May 2022 (11:10:00 CEST)
ARTICLE
|
doi:10.20944/preprints202104.0724.v1
Subject:
Chemistry And Materials Science,
Biomaterials
Keywords:
TNBC; dasatinib; poly(styrene-co-maleic acid) micelles; nanoformulation; metabolism; EPR; nanomedicine; targeted therapy.
Online: 27 April 2021 (13:56:12 CEST)
ARTICLE
Subject:
Medicine And Pharmacology,
Obstetrics And Gynaecology
Keywords:
HBOC; statewide random sampling; cancer survivorship; targeted intervention; tailored intervention; black participants; family recruitment
Online: 5 September 2019 (16:16:34 CEST)
REVIEW
|
doi:10.20944/preprints201902.0245.v1
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
cyclin-dependent kinases; cyclin-dependent kinase 4 and 6 inhibitors; targeted therapies; breast cancer
Online: 27 February 2019 (04:48:54 CET)
ARTICLE
|
doi:10.20944/preprints201609.0024.v1
Subject:
Medicine And Pharmacology,
Neuroscience And Neurology
Keywords:
neurofibromatosis type 1; congenital pseudarthrosis of the tibia; whole-exome sequencing; targeted sequencing; BCOR
Online: 7 September 2016 (11:19:00 CEST)
ARTICLE
|
doi:10.20944/preprints202309.2064.v1
Subject:
Computer Science And Mathematics,
Security Systems
Keywords:
adversarial attacks; artificial intelligence; machine learning; defense mechanisms; system integrity; model vulnerabilities; advanced attack techniques; Fast Gradient Sign Method (FGSM); Carlini and Wagner Attack (C&W); targeted attacks; non-targeted attacks; blackbox attacks
Online: 29 September 2023 (08:42:10 CEST)
REVIEW
|
doi:10.20944/preprints202403.1011.v1
Subject:
Biology And Life Sciences,
Biology And Biotechnology
Keywords:
retinoblastoma; RB1; E2F; Targeted Therapy; Therapeutic Vulnerabilities; Spliceosome; Cell Cycle; Epigenetic Regulators; Ubiquitin-Proteasome Pathway
Online: 18 March 2024 (10:29:38 CET)
ARTICLE
|
doi:10.20944/preprints202401.0334.v1
Subject:
Public Health And Healthcare,
Other
Keywords:
recurrent ovarian cancer; platinum-sensitive relapse; platinum-resistant relapse; platinum refractory relapse; targeted therapy; chemotherapy
Online: 4 January 2024 (04:18:09 CET)
CASE REPORT
|
doi:10.20944/preprints202306.1950.v1
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
inflammatory breast carcinoma; targeted biological therapy; HER2 overexpression; multidisciplinary treatment; aggressive cancer management; systemic chemotherapy
Online: 28 June 2023 (07:12:56 CEST)
REVIEW
|
doi:10.20944/preprints202210.0450.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
Tumor microenvironment; stromal cells; immune cells; ECM; cancer hallmarks; hypoxia; exosomes; drug resistance; targeted therapy
Online: 28 October 2022 (09:57:34 CEST)
REVIEW
|
doi:10.20944/preprints202208.0220.v1
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
Molecular switches; oncolytic vectors; patient-specific ubiquitous mutations; targeted therapy; multi-region sequencing; molecular biology
Online: 11 August 2022 (11:50:12 CEST)
ARTICLE
|
doi:10.20944/preprints202204.0137.v1
Subject:
Biology And Life Sciences,
Animal Science, Veterinary Science And Zoology
Keywords:
Taihe silky fowl; metabolic components; un-targeted metabolome; breed and feed; biosynthesis of amino acids
Online: 15 April 2022 (05:47:06 CEST)
ARTICLE
|
doi:10.20944/preprints202109.0300.v1
Subject:
Computer Science And Mathematics,
Applied Mathematics
Keywords:
CAR T; Targeted Radionuclide Therapy; TRT; Mathematical Model; Multiple Myeloma; Immunotherapy; Daratumumab; CS1; Combination Therapy
Online: 17 September 2021 (09:32:33 CEST)
ARTICLE
|
doi:10.20944/preprints202106.0638.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
pancreatic ductal adenocarcinoma; targeted therapies; therapeutic resistance; tumor microenvironment; desmoplasia; collagen; collagenase; attenuated Salmonella typhimurium
Online: 28 June 2021 (10:36:31 CEST)
ARTICLE
|
doi:10.20944/preprints202104.0692.v1
Subject:
Biology And Life Sciences,
Virology
Keywords:
RACK1; HIV-1; IRES; Hepatitis C; HCV; AZT; HTA; Host-targeted antiviral; HEK293T; SD29-14
Online: 26 April 2021 (20:35:00 CEST)
COMMENTARY
|
doi:10.3390/sci2030070
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
small molecule inhibitor; personalized medicine; precision medicine; oncology; targeted therapy; drug delivery; drug screening; chemotherapy
Online: 8 September 2020 (00:00:00 CEST)
REVIEW
|
doi:10.20944/preprints202312.2256.v1
Subject:
Medicine And Pharmacology,
Hematology
Keywords:
acute myeloid leukemia; TP53 mutations; TP53-mutated acute myeloid leukemia; novel targeted AML therapies; AML immunotherapies
Online: 29 December 2023 (05:27:17 CET)
REVIEW
|
doi:10.20944/preprints202311.0094.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
Casein Kinase II; Musculoskeletal; Osteoarthritis; Osteoporosis; CX-4945; CIBG-300; Cell Signaling; Drug Development; Targeted therapy
Online: 1 November 2023 (13:18:42 CET)
REVIEW
|
doi:10.20944/preprints202103.0143.v1
Subject:
Medicine And Pharmacology,
Immunology And Allergy
Keywords:
antioxidants; alcohol metabolism; hepatoprotective; anti-ALD; mitochondrial dysfunction; mitochondria-targeted; oxidative stress; and cytochrome P450 2E1
Online: 4 March 2021 (09:13:05 CET)
REVIEW
|
doi:10.20944/preprints201811.0143.v1
Subject:
Medicine And Pharmacology,
Urology And Nephrology
Keywords:
clear cell renal cell carcinoma; tumor evolution; tumor ecology; intratumor heterogeneity; multisite tumor sampling; targeted therapy
Online: 6 November 2018 (13:30:54 CET)
ARTICLE
|
doi:10.20944/preprints201804.0307.v1
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
gastric cancer; ramucirumab; paclitaxel; second line therapy; vascular endothelial growth factor receptor 2; targeted therapy; nutrition
Online: 24 April 2018 (06:01:56 CEST)
ARTICLE
|
doi:10.20944/preprints202312.1002.v1
Subject:
Medicine And Pharmacology,
Pulmonary And Respiratory Medicine
Keywords:
intranasal spray; drug delivery; respiratory transport modeling; respiratory diseases; upper airway physiology; targeted nasal therapy; gentlemistTM technology
Online: 13 December 2023 (13:05:13 CET)
ARTICLE
|
doi:10.20944/preprints202105.0546.v1
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
triple negative breast cancer; Pembrolizumab; Atezolizumab; chemotherapy; anti-PD-L1; biomarkers; targeted therapies; development of novel drugs
Online: 24 May 2021 (09:23:50 CEST)
REVIEW
|
doi:10.20944/preprints202001.0030.v1
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
histone deacetylase 6 inhibitor; personalized treatment; heat shock protein 90α; leukemia stem cells; imatinib resistance; targeted therapy
Online: 4 January 2020 (06:18:22 CET)
ARTICLE
|
doi:10.20944/preprints202306.1455.v1
Subject:
Medicine And Pharmacology,
Pulmonary And Respiratory Medicine
Keywords:
Acute respiratory illness; critical care; recombinant tissue plasminogen activator; nebulization, fibrinolytics, COVID-19 pandemic, inhaled medication, targeted therapy
Online: 20 June 2023 (14:59:12 CEST)
REVIEW
|
doi:10.20944/preprints202301.0053.v1
Subject:
Chemistry And Materials Science,
Nanotechnology
Keywords:
gastrin releasing peptide receptor; GRPR; bombesin receptor subtype 2; BB2; bombesin; targeted therapy; molecular imaging; theranostics; nanotechnology; nanoparticle; nanomedicine
Online: 4 January 2023 (03:19:26 CET)
REVIEW
|
doi:10.20944/preprints202401.1989.v1
Subject:
Biology And Life Sciences,
Life Sciences
Keywords:
cancer; cancer treatment; cancer treatments history; cancer therapy; oncology; immunology; chemotherapy; radiation therapy; ADC; CART; BiTE; targeted therapy; cancer genetics
Online: 30 January 2024 (03:28:49 CET)
REVIEW
|
doi:10.20944/preprints202401.0233.v1
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
Gold nanoparticle; nanomedicine; glioblastoma multiforme; blood-brain barrier; brain tumor treatment; targeted drug delivery; radiation treatment; boron neutron capture therapy
Online: 3 January 2024 (10:03:43 CET)
REVIEW
|
doi:10.20944/preprints202305.0720.v2
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
Prostate cancer; androgen receptor; AR signaling pathway; disease progression; therapeutic re-sistance; personalized treatment; androgen deprivation therapy; AR-targeted therapies
Online: 25 September 2023 (16:46:10 CEST)
REVIEW
|
doi:10.20944/preprints201810.0204.v2
Subject:
Biology And Life Sciences,
Biology And Biotechnology
Keywords:
DNA origami; aptamer; DNA nanotechnology; protein nano array; biosensor; logic gate; enzyme cascade; drug delivery system; targeted therapy; molecular robotics
Online: 22 October 2018 (10:57:21 CEST)
REVIEW
|
doi:10.20944/preprints201807.0052.v1
Subject:
Biology And Life Sciences,
Agricultural Science And Agronomy
Keywords:
Plant stress, abiotic stress, biotic stress, metabolomics, phytometabolomics, sensomics, phytohormonics, LC-MS/MS, NMR, targeted metabolomics, untargeted metabolomics, functional food.
Online: 3 July 2018 (14:18:19 CEST)
REVIEW
|
doi:10.20944/preprints201608.0115.v2
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
oncogenes; oncogene addiction; carcinogenesis; transcription factor; cancer genome; gene fusion; cancer genetics; cancer stem cell; targeted cancer therapy; personalized medicine
Online: 14 September 2016 (08:30:41 CEST)
REVIEW
|
doi:10.20944/preprints202305.2222.v1
Subject:
Biology And Life Sciences,
Neuroscience And Neurology
Keywords:
Psychedelic renaissance; Mental health; Therapeutic potential; Gut microbiome; Psychedelic substances; Personalized medicine; Gut-brain axis; Mood regulation; Microbiome-targeted interventions; Psychopharmacology
Online: 31 May 2023 (10:32:05 CEST)
ARTICLE
|
doi:10.20944/preprints202208.0144.v1
Subject:
Medicine And Pharmacology,
Pharmacology And Toxicology
Keywords:
mucosal immunization; mucosal vaccine; vaccine delivery; administration volume; targeted vaccines; M cell targeting; dendritic cell targeting; C5aR1; C5a1R; CD88; EP54; EP67
Online: 8 August 2022 (10:17:30 CEST)
REVIEW
|
doi:10.20944/preprints202406.0155.v1
Subject:
Biochemistry And Molecular Biology,
Biology And Life Sciences
Keywords:
CAR-T cell therapy; Hematologic malignancies; Cytokine release syndrome; Antigen mutation; γ δ CAR-T cells; Multi-targeted CAR-T cells; Precision medicine
Online: 4 June 2024 (16:12:58 CEST)
ARTICLE
|
doi:10.20944/preprints202201.0380.v1
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
Therapeutic biomarkers; circulating tumor cells; Immunocytochemistry; targeted therapy; Fluorescence in situ hybridization (FISH); Immune Checkpoint Inhibitors; Liquid Biopsy; Hormonal Treatments; Breast Cancer; Lung Cancer
Online: 25 January 2022 (11:31:05 CET)
REVIEW
|
doi:10.20944/preprints202312.1050.v1
Subject:
Medicine And Pharmacology,
Medicine And Pharmacology
Keywords:
smart nanocarriers; light-responsive liposomes; dual-targeted stimuli-responsive liposomes; phototriggered targeting strategies; light-triggering mechanisms; nir-responsive nanocarriers; nano carriers current challenges; future perspectives
Online: 14 December 2023 (05:55:40 CET)
ARTICLE
|
doi:10.20944/preprints202301.0500.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
Alzheimer’s Disease (AD) mitochondria; endoplasmic reticulum (ER); serial block-face scanning electron microscopy (SBFSEM); three-dimensional electron microscopy (3D EM); small molecule mitochondria targeted therapeutics
Online: 27 January 2023 (10:08:59 CET)
ARTICLE
|
doi:10.20944/preprints202212.0542.v2
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
safety analysis; targeted therapy; monoclonal antibody therapy; immune checkpoint inhibibitors; tyrosine kinase inhibitors; breast cancer; gynecological cancer; Helixor; Viscum album L.; PARP inhibitors; CDK 4/6 inhibitors
Online: 30 December 2022 (12:00:35 CET)
REVIEW
|
doi:10.20944/preprints201912.0135.v1
Subject:
Medicine And Pharmacology,
Medicine And Pharmacology
Keywords:
vascular homing peptide; cell penetrating peptide; angiogenesis; vascular heterogeneity; fibrosis; targeted delivery; decorin; transforming growth factor-β (tgf-β), bystander effect, cendr peptide; tissue regeneration; regenerative medicine
Online: 10 December 2019 (15:02:39 CET)
ARTICLE
|
doi:10.20944/preprints202403.0518.v1
Subject:
Computer Science And Mathematics,
Discrete Mathematics And Combinatorics
Keywords:
COVID19; Chern-Simons Topological; QED (Quantum Electrodynamics); Homeopathic medicine; Water Memory; AI-Quantum computing; Quantum-Inspired Evolutionary Algorithm Predictive Toxicology; QSAR Quantum gates; CS Supergravity Quantum Foam; Cheminformatics artificial intelligence; Phase Data Mining; Machine Learning; Euclid Chemical space exploration; (bosonic) Quantum fields Theory (QFT); Angiotensin Receptor Neprilysin targeted DRVYIHPFX mimetic Holomorphic Ligands; Hidden Entanglement Negativity Translations; Uncertainty Quantum Relationships; Quantum fields theory; Quantum information; HyperGeometric Functions; Chemical Block Systems; Black Hole Paradox Generalizations; SphericalHarmonicY-Supersymmetry breaking foundations; WhittakerM Functions; Hypergeometric1F1 Functions; Turing Machine Learning Ruled Calculations; Avogadro Number’ s oriented Quantum Homeopathy Hidden Entanglement Negativities; Quantum foam; non-commutative geometry; small molecule ligand engineering; prot
Online: 11 March 2024 (03:52:07 CET)
REVIEW
|
doi:10.3390/sci2030068
Subject:
Medicine And Pharmacology,
Tropical Medicine
Keywords:
COVID-19; pooling clinical trials; hyperinfection; steroids; treatment; targeted healthcare; population health management; cancer treatment; clinical research; clinical trials; developing vaccines; ranking and rating hospital quality; school closures; interventions for delirium; assessments of COVID-19 death inequities; regulatory safeguards; preventing child abuse and maltreatment; prevalence of health care worker burnout; nursing home ratings; challenging oncology practice; addressing racial; ethnic; social and economic divides; violence against sexual minority adolescents; primary tumors; metastasis; stages of cancer; reforming cancer clinical trials; supporting carers; protection and prevention; benign and malignant tumors; reforming cancer clinical trials; protection of healthcare personnel; comparing excess deaths in NYC; 1918 influenza pandemic; the possibility of full recovery from COVID-19; mental health impact of COVID-19 on young adults; ranking and rating nursing home quali
Online: 21 August 2020 (00:00:00 CEST)