ARTICLE
|
doi:10.20944/preprints202008.0621.v2
Subject:
Biology And Life Sciences,
Anatomy And Physiology
Keywords:
Clustering; Mutation; Amino acid substitution; Structural proteins; Biochemical properties; Functional sub-domains
Online: 4 March 2021 (10:17:15 CET)
COMMUNICATION
|
doi:10.20944/preprints202103.0113.v1
Subject:
Medicine And Pharmacology,
Immunology And Allergy
Keywords:
blood-based mutation burden (bTMB); cancer immunotherapy; immune checkpoint inhibitor (ICI); biomarker; mutation
Online: 2 March 2021 (21:45:40 CET)
ARTICLE
|
doi:10.20944/preprints202102.0503.v1
Subject:
Computer Science And Mathematics,
Algebra And Number Theory
Keywords:
Machine Learning; Software Testing; Quality Attributes; Deep Learning; Model Mutation testing; DNN; DL
Online: 23 February 2021 (09:22:02 CET)
ARTICLE
|
doi:10.20944/preprints202102.0501.v1
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
age; glioma; mutation; TCGA; transcriptomic analysis
Online: 23 February 2021 (08:16:52 CET)
ARTICLE
|
doi:10.20944/preprints202011.0717.v1
Subject:
Medicine And Pharmacology,
Immunology And Allergy
Keywords:
OYST; molecular characteristics; targetable mutation; patients’ outcome
Online: 30 November 2020 (11:06:47 CET)
REVIEW
Subject:
Medicine And Pharmacology,
Immunology And Allergy
Keywords:
Mutation; Epigenetic; Genetic; Neoplastic transformation; Stem cell; Tumor classification
Online: 30 November 2020 (08:26:34 CET)
ARTICLE
|
doi:10.20944/preprints202011.0524.v1
Subject:
Chemistry And Materials Science,
Analytical Chemistry
Keywords:
zinc finger; protein; MM/GBSA; DNA binding; molecular dynamics; mutation; linkers
Online: 19 November 2020 (21:21:37 CET)
REVIEW
|
doi:10.20944/preprints202002.0261.v2
Subject:
Biology And Life Sciences,
Virology
Keywords:
epidemics; molecular replicators; mutation; quasispecies; recombination; self-assembly; phase transitions
Online: 29 October 2020 (09:30:44 CET)
REVIEW
|
doi:10.20944/preprints202010.0514.v1
Subject:
Medicine And Pharmacology,
Immunology And Allergy
Keywords:
Single-Nucleotide Polymorphisms; Point Mutation; Chemokines; T-cells; Viral Infection; Tumorigenesis; T-cell Surface; Immune Response
Online: 26 October 2020 (11:08:40 CET)
REVIEW
|
doi:10.20944/preprints202010.0510.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
disease-associated mutation; IDR; intrinsically disordered region; LLPS; phase separation; PTM; Ahr; AhRR; SIM1; SIM2; Hif-2α; NPAS4; ARNT2; BMAL1; disorder prediction; LLPS prediction; cancer; HuVarBase; catGranule prediction
Online: 26 October 2020 (10:30:47 CET)
ARTICLE
|
doi:10.20944/preprints202010.0239.v1
Subject:
Physical Sciences,
Acoustics
Keywords:
KRas-4B; mutation; post-translational modification; HVR; anionic plasma membrane; signaling; cholesterol
Online: 12 October 2020 (12:31:28 CEST)
ARTICLE
|
doi:10.20944/preprints202009.0483.v1
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
next-generation sequencing; colorectal cancer; ATM mutation; FBXW7 mutation
Online: 20 September 2020 (15:20:52 CEST)
REVIEW
|
doi:10.20944/preprints202009.0395.v1
Subject:
Biology And Life Sciences,
Virology
Keywords:
Spike protein, V483A, substitution mutation, virus-host cell interaction, high transmission, infectivity.
Online: 17 September 2020 (10:43:02 CEST)
REVIEW
|
doi:10.20944/preprints202009.0279.v1
Subject:
Biology And Life Sciences,
Immunology And Microbiology
Keywords:
selection; mutation; genetic drift; adaptation; ploidy drive; genome instability
Online: 13 September 2020 (11:48:30 CEST)
ARTICLE
|
doi:10.20944/preprints202009.0185.v1
Subject:
Biology And Life Sciences,
Endocrinology And Metabolism
Keywords:
eel luteinizing hormone receptor; constitutively activating mutation; inactivating mutation; cyclic adenosine monophosphate response; cell surface loss of receptor
Online: 8 September 2020 (10:56:48 CEST)
ARTICLE
Subject:
Medicine And Pharmacology,
Urology And Nephrology
Keywords:
Immune cell; DNA CpGs; Bladder cancer; Subtype; mutation; CNV; Immune score; Immune Checkpoints
Online: 5 September 2020 (06:00:06 CEST)
ARTICLE
|
doi:10.20944/preprints202008.0447.v1
Subject:
Biology And Life Sciences,
Virology
Keywords:
spike protein; SARS-CoV-2; mutation; drug repurposing; digitoxin
Online: 20 August 2020 (08:24:41 CEST)
CASE REPORT
|
doi:10.20944/preprints202008.0198.v1
Subject:
Biology And Life Sciences,
Immunology And Microbiology
Keywords:
SARS-CoV-2; coinfection; diabetes, bloodstream infection; Candida glabrata; echinocandin resistance; FKS mutation
Online: 7 August 2020 (12:54:12 CEST)
BRIEF REPORT
|
doi:10.20944/preprints202008.0148.v1
Subject:
Biology And Life Sciences,
Virology
Keywords:
Alignment-free software tool; Coronavirus; COVID-19; D614G mutation; Sarbecovirus; SARS-CoV; SARS-CoV-2; Spike glycoprotein
Online: 6 August 2020 (10:12:00 CEST)
ARTICLE
|
doi:10.20944/preprints202007.0739.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
Lung-molGPA; exon 19 deletion; Leu858Arg; rare mutation; prognostic implication
Online: 31 July 2020 (09:30:53 CEST)
ARTICLE
|
doi:10.20944/preprints202007.0132.v1
Subject:
Biology And Life Sciences,
Biology And Biotechnology
Keywords:
coronavirus; spike protein; database; sequence alignment; mutation; homology model; hydrophobic amino acids
Online: 7 July 2020 (16:49:04 CEST)
ARTICLE
|
doi:10.20944/preprints202007.0049.v1
Subject:
Biology And Life Sciences,
Virology
Keywords:
Sars-CoV-2; proteome; mutation; ORF3a; Nucleoprotein; Nsp2
Online: 5 July 2020 (06:54:01 CEST)
ARTICLE
|
doi:10.20944/preprints202006.0032.v1
Subject:
Medicine And Pharmacology,
Pathology And Pathobiology
Keywords:
SARS-CoV-2; Spike protein; COVID-19; Mutation; hACE2 Receptor; Real-time PCR; Vaccine
Online: 4 June 2020 (08:48:03 CEST)
ARTICLE
|
doi:10.20944/preprints202005.0463.v1
Subject:
Biology And Life Sciences,
Virology
Keywords:
comparative genomics; SARS-CoV-2; microevolution; quasi-species; point mutation; disinfectants as mutagens
Online: 28 May 2020 (16:21:05 CEST)
ARTICLE
|
doi:10.20944/preprints202005.0407.v1
Subject:
Biology And Life Sciences,
Virology
Keywords:
SARS-CoV-2; spike protein; D614G mutation; genotype distribution; furin cleavage site; secondary structure; sequence analysis; homology modeling
Online: 24 May 2020 (20:31:16 CEST)
BRIEF REPORT
Subject:
Biology And Life Sciences,
Virology
Keywords:
COVI-19; SARS-CoV-2; virus; mutation; polymorphism; genome sequence
Online: 21 May 2020 (04:09:53 CEST)
BRIEF REPORT
|
doi:10.20944/preprints202004.0476.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
androgen insensitivity syndrome; androgen receptor; ligand binding domain; pathogenic mutation; bioinformatics
Online: 27 April 2020 (03:59:38 CEST)
ARTICLE
|
doi:10.20944/preprints202004.0450.v1
Online: 24 April 2020 (14:19:02 CEST)
REVIEW
|
doi:10.20944/preprints202004.0333.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
bitter gourd; breeding; genetic diversity; genomics; heterosis; molecular breeding; mutation breeding
Online: 19 April 2020 (06:00:00 CEST)
HYPOTHESIS
|
doi:10.20944/preprints202004.0286.v1
Subject:
Biology And Life Sciences,
Virology
Keywords:
SARS-CoV-2; domain-fold; evolutionary fingerprint; conserved domain; point mutation; recombination
Online: 16 April 2020 (16:13:13 CEST)
BRIEF REPORT
|
doi:10.20944/preprints202004.0154.v1
Subject:
Biology And Life Sciences,
Immunology And Microbiology
Keywords:
SARS-CoV2; spike glycoprotein; mutation
Online: 9 April 2020 (13:15:21 CEST)
REVIEW
|
doi:10.20944/preprints202002.0099.v1
Subject:
Biology And Life Sciences,
Virology
Keywords:
retroviruses; HIV-1; reverse transcriptase; mutation rate; drug resistance, allostery
Online: 7 February 2020 (11:50:11 CET)
ARTICLE
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
Insecta; Chemosensory proteins; Odorant binding proteins; Peptide mutation; Cell evolution; Abiogenesis
Online: 30 January 2020 (03:02:21 CET)
ARTICLE
|
doi:10.20944/preprints202001.0130.v1
Subject:
Biology And Life Sciences,
Biology And Biotechnology
Keywords:
PD-1; PD-L1; Cancer-linked genetic mutation; Electrostatic repulsion; Structural evolution
Online: 12 January 2020 (16:58:35 CET)
REVIEW
|
doi:10.20944/preprints201912.0131.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
single nucleotide polymorphism; docking; molecular dynamics; in-silico studies; protein dynamics; missense; prediction algorithm; mutation
Online: 10 December 2019 (07:56:43 CET)
HYPOTHESIS
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
incurable disease; chronic disease; cancer theory; central nervous system; state memory; mutation; tissue ecosystem; emotion; stress; exercise; baseline biochemical and cellular processes
Online: 24 November 2019 (14:50:49 CET)
ARTICLE
|
doi:10.20944/preprints201910.0373.v1
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
malignant melanoma; BRAF V600E mutation; proteomics; mass spectrometry genetics; heterogeneity; prognosis
Online: 31 October 2019 (10:36:32 CET)
ARTICLE
|
doi:10.20944/preprints201909.0012.v2
Subject:
Biology And Life Sciences,
Insect Science
Keywords:
Ace-1 G119S mutation; insecticide resistance; Anopheles gambiae; Cameroon; malaria
Online: 8 October 2019 (11:49:05 CEST)
ARTICLE
Subject:
Medicine And Pharmacology,
Dermatology
Keywords:
skin melanoma, KIT mutation, Sanger sequencing
Online: 6 August 2019 (12:33:31 CEST)
ARTICLE
|
doi:10.20944/preprints201907.0117.v1
Subject:
Biology And Life Sciences,
Endocrinology And Metabolism
Keywords:
eel luteinizing hormone receptor, constitutively activating mutation, inactivating mutation, cAMP responses.
Online: 8 July 2019 (12:38:11 CEST)
ARTICLE
|
doi:10.20944/preprints201907.0025.v1
Subject:
Biology And Life Sciences,
Cell And Developmental Biology
Keywords:
reelin; CTR; point mutation; secretion; RELN
Online: 1 July 2019 (17:22:14 CEST)
ARTICLE
|
doi:10.20944/preprints201905.0379.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
toxin; antitoxin; mutation
Online: 31 May 2019 (08:36:38 CEST)
REVIEW
|
doi:10.20944/preprints201905.0130.v1
Subject:
Biology And Life Sciences,
Plant Sciences
Keywords:
induced mutagenesis; fast neutron irradiation; mutation mapping; deletagene; next-generation sequencing technologies; reverse genetics
Online: 10 May 2019 (14:38:21 CEST)
ARTICLE
|
doi:10.20944/preprints201812.0205.v1
Subject:
Biology And Life Sciences,
Ecology, Evolution, Behavior And Systematics
Keywords:
Diminished fitness return, mutation rate tuning, Darwinian evolution; neutral evolution; punctuated equilibrium; unified evolutionary theory
Online: 17 December 2018 (16:10:52 CET)
ARTICLE
|
doi:10.20944/preprints201812.0136.v1
Subject:
Environmental And Earth Sciences,
Remote Sensing
Keywords:
Land subsidence; InSAR; Small baseline interferometry; Mann-Kendall mutation test; Fishnet
Online: 11 December 2018 (16:49:47 CET)
ARTICLE
|
doi:10.20944/preprints201811.0280.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
HSP47; missense mutation; mutational hotspot; variant analysis; cancer database; chaperone
Online: 12 November 2018 (10:23:29 CET)
COMMUNICATION
|
doi:10.20944/preprints201808.0108.v1
Subject:
Medicine And Pharmacology,
Ophthalmology
Keywords:
congenital cataract; consanguineous; circadian; mutation
Online: 6 August 2018 (10:04:11 CEST)
REVIEW
|
doi:10.20944/preprints201807.0478.v1
Subject:
Medicine And Pharmacology,
Pathology And Pathobiology
Keywords:
pheochromocytoma; paraganglioma; GAPP; metastasis; prognosis; catecholamine; gene mutation; immunohistochemistry; pathology; diagnosis
Online: 25 July 2018 (11:41:52 CEST)
ARTICLE
|
doi:10.20944/preprints201807.0154.v1
Subject:
Biology And Life Sciences,
Plant Sciences
Keywords:
bread wheat; correlations, gamma, grain nutrients concentrations; mutation, phytic acid; metals bioavailability
Online: 9 July 2018 (15:39:51 CEST)
ARTICLE
|
doi:10.20944/preprints201805.0088.v1
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
p53; proteasome inhibitor; endometrial cancer; ovarian cancer; gain-of-function mutation
Online: 4 May 2018 (09:03:27 CEST)
REVIEW
|
doi:10.20944/preprints201707.0074.v1
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
cancer etiology; carcinogenesis; cancer prevention; stem cells; cancer stem cells; stem cell environment; cells of origin in cancer; somatic mutation theory of cancer
Online: 26 July 2017 (08:42:41 CEST)