REVIEW
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
Mollusc; selective breeding; gene editing; disease resistance; transgenesis; CRISPR/Cas9
Online: 15 October 2020 (16:06:27 CEST)
ARTICLE
|
doi:10.20944/preprints202003.0424.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
primary congenital glaucoma; exome sequencing; GUCA1C; GCAP3; zebrafish; CRISPR/Cas9
Online: 29 March 2020 (06:33:17 CEST)
REVIEW
|
doi:10.20944/preprints202312.1100.v1
Subject:
Biology And Life Sciences,
Plant Sciences
Keywords:
Solanum lycopersicum L.; CRISPR/Cas9; RNA interference; silencing; overexpression; transcription factors
Online: 14 December 2023 (12:20:58 CET)
REVIEW
|
doi:10.20944/preprints202309.0701.v1
Subject:
Biology And Life Sciences,
Neuroscience And Neurology
Keywords:
Brain disorders; Transformative treatments; Disease specificity; Stem cell models; CRISPR; Immunotherapies.
Online: 11 September 2023 (13:40:41 CEST)
ARTICLE
|
doi:10.20944/preprints202307.0376.v1
Subject:
Biology And Life Sciences,
Life Sciences
Keywords:
gene expression; knockdown; CRISPR/Cas13d; shisa -2; mesp ab; somite formation
Online: 6 July 2023 (05:39:07 CEST)
ARTICLE
|
doi:10.20944/preprints202304.1197.v1
Subject:
Biology And Life Sciences,
Biology And Biotechnology
Keywords:
B-cells, hypoxia, miRNA, CRISPR/Cas9, leukemia, gene expression, cell viability
Online: 29 April 2023 (03:34:08 CEST)
ARTICLE
|
doi:10.20944/preprints202105.0142.v1
Subject:
Medicine And Pharmacology,
Immunology And Allergy
Keywords:
Cancer Immunotherapy; Cancer Vaccine; Cancer Antigens; CRISPR-Cas9; Engineered T Cells.
Online: 7 May 2021 (11:10:13 CEST)
ARTICLE
|
doi:10.20944/preprints202011.0723.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
Fanconi anemia; gene editing; FANCA; head and neck cancer; CRISPR/Cas9
Online: 30 November 2020 (11:55:45 CET)
OPINION
|
doi:10.20944/preprints201608.0016.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
parallel DNA; antiparallel DNA; PCR; CRISPR; nucleic acid hybridization; microarray; siRNA
Online: 2 August 2016 (10:42:27 CEST)
REVIEW
|
doi:10.20944/preprints202207.0404.v1
Subject:
Biology And Life Sciences,
Plant Sciences
Keywords:
Abiotic stress; biotic stress; biotechnology; climate change; CRISPR; crop improvement; genome editing
Online: 26 July 2022 (10:44:22 CEST)
ARTICLE
|
doi:10.20944/preprints202105.0333.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
genome editing; CRISPR; protoplast; , targeted mutagenesis; TREX2; construct validation; transi-ent expression
Online: 14 May 2021 (13:44:26 CEST)
REVIEW
|
doi:10.20944/preprints201906.0032.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
nucleic acids analogs, antisense, CRISPR, antibiotic resistance, myotonic dystrophy, cholesterol, hematologic malignancy,
Online: 5 June 2019 (08:11:12 CEST)
REVIEW
|
doi:10.20944/preprints202403.0393.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
DNA; Molecular Choreography; Genetic Information; Epigenetic Modifications; CRISPR-Cas9; DNA Replication; Gene Editing
Online: 8 March 2024 (01:54:59 CET)
ARTICLE
|
doi:10.20944/preprints202312.0701.v1
Subject:
Biology And Life Sciences,
Biology And Biotechnology
Keywords:
Saccharomyces cerevisiae; genome editing; site-directed mutagenesis; CRISPR/Cas9; high-fidelity Cas9 forms
Online: 12 December 2023 (07:43:14 CET)
ARTICLE
|
doi:10.20944/preprints202109.0051.v1
Subject:
Biology And Life Sciences,
Insect Science
Keywords:
Helicoverpa zea; Bollworm; CRISPR; Cry1A; Bt Toxin; Genome Editing; Knockout; Functional Genomics; Resistance
Online: 3 September 2021 (08:19:44 CEST)
ARTICLE
|
doi:10.20944/preprints202104.0474.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
CRISPR/Cas9; knockout; rescue; desiccation tolerance; anhydrobiosis; Polypedilum vanderplanki; HSF1; insect cell; Pv11
Online: 19 April 2021 (12:17:34 CEST)
ARTICLE
|
doi:10.20944/preprints202010.0102.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
lncRNA; LINC00961; SPAAR; scRNASeq; CRISPR/Cas9; cardiovascular physiology; fetal growth restriction; myocardial infarction
Online: 5 October 2020 (17:47:46 CEST)
ARTICLE
|
doi:10.20944/preprints202404.0058.v1
Subject:
Biology And Life Sciences,
Biology And Biotechnology
Keywords:
bioactive carotenoid; diatoxanthin; Phaeodactylum tricornutum; CRISPR/Cas9 gene editing; zeaxanthin epoxidase; commercial production line
Online: 2 April 2024 (12:46:38 CEST)
REVIEW
|
doi:10.20944/preprints202402.0284.v1
Subject:
Biology And Life Sciences,
Biology And Biotechnology
Keywords:
Phage display, phage therapy, infectious diseases, mAbs, cancer, theranostics, Alzhiemer’s disease, CRISPR-Cas9 system.
Online: 5 February 2024 (12:21:04 CET)
ARTICLE
|
doi:10.20944/preprints202312.0628.v1
Subject:
Biology And Life Sciences,
Virology
Keywords:
IFITM; Influenza A virus; Human cells; WI-38; Genome editing; CRISPR/Cas9; RNA-seq
Online: 8 December 2023 (12:42:54 CET)
REVIEW
|
doi:10.20944/preprints202212.0231.v1
Subject:
Biology And Life Sciences,
Biology And Biotechnology
Keywords:
methylerythritol phosphate (MEP) pathway; photosynthesis; isoprenoids; lipids; biofuels; gene editing; CRISPR; riboswitch; riboregulators; nanocompartments
Online: 13 December 2022 (07:22:52 CET)
REVIEW
|
doi:10.20944/preprints202009.0490.v1
Subject:
Biology And Life Sciences,
Cell And Developmental Biology
Keywords:
base editing; prime editing; ABE; SCD; sickle cell disease; sickle cell anemia; CRISPR; Cas9
Online: 21 September 2020 (04:23:21 CEST)
ARTICLE
|
doi:10.20944/preprints201810.0451.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
CTCF; tumour suppressor gene; haploinsufficiency; zinc finger; CRISPR/Cas9; cancer; endometrial cancer; gene editing
Online: 19 October 2018 (11:29:01 CEST)
REVIEW
|
doi:10.20944/preprints202308.0453.v1
Subject:
Medicine And Pharmacology,
Clinical Medicine
Keywords:
gene editing 1; CRISPR 2; gRNA 3; autoimmune disorders 4; nuclease 5; hereditary disorders 6
Online: 4 August 2023 (19:15:10 CEST)
REVIEW
|
doi:10.20944/preprints202306.0686.v1
Subject:
Biology And Life Sciences,
Biology And Biotechnology
Keywords:
phosphate homeostasis; transcription factors; phosphate starvation response factors; SPX; proteomics; post-translational; CRISPR; gene editing
Online: 9 June 2023 (08:20:58 CEST)
REVIEW
|
doi:10.20944/preprints202403.0103.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
DNA; genomics; sequencing; gene regulation; precision medicine; DNA nanotechnology; bioinformatics; CRISPR-Cas9; gene editing; personalized Medicine
Online: 4 March 2024 (09:54:47 CET)
ARTICLE
|
doi:10.20944/preprints202311.1585.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
prime editing; CRISPR/Cas9; gene editing; gene therapy; RYR1-related diseases; neuromuscular diseases; RYR1 gene; mutations
Online: 24 November 2023 (08:51:01 CET)
ARTICLE
|
doi:10.20944/preprints202212.0442.v1
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
P21; CDKN1A; glioblastoma; senescence; cancer senescence; gene overexpression; gene knock-in; CRISPR/Cas9; dCas; dCas-VPR
Online: 23 December 2022 (04:10:22 CET)
ARTICLE
|
doi:10.20944/preprints202106.0169.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
melanoma initiating cells; CD133; drug resistance; apoptosis; caspase activation; CRISPR-Cas9 knockout; AKT; BAD; BCL-2 family
Online: 7 June 2021 (12:11:10 CEST)
REVIEW
|
doi:10.20944/preprints201810.0010.v1
Subject:
Medicine And Pharmacology,
Ophthalmology
Keywords:
Gene therapy, gene editing, CRISPR/Cas9, Cas12a, dual AAV, triple AAV, clinical trials, retina, hereditary retinal dystrophies
Online: 1 October 2018 (13:52:23 CEST)
REVIEW
|
doi:10.20944/preprints202310.2051.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
higher plants; reactive oxygen species; antioxidants; isoprenoids; plastoquinone; carotenoids; tocopherol; ubiquinone; flavonoids; ascorbic acid; glutathione; transgenesis; CRISPR/Cas9
Online: 31 October 2023 (12:21:23 CET)
ARTICLE
|
doi:10.20944/preprints202312.0830.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
CRISPR/Cas9 technique; mRNAs; poly(ADP-ribose) polymerase 1; poly(ADP- ribosyl)ation.; activity of base excision repair enzymes
Online: 12 December 2023 (11:08:39 CET)
REVIEW
|
doi:10.20944/preprints201905.0386.v1
Subject:
Biology And Life Sciences,
Immunology And Microbiology
Keywords:
CRISPR, clonal selection, totipotent, multipotent, T cell receptors, B cell receptors, precommitted, lymphocyte, T cell vaccine, T cell vaccination
Online: 31 May 2019 (11:12:33 CEST)
REVIEW
|
doi:10.20944/preprints202403.0424.v1
Subject:
Biology And Life Sciences,
Biology And Biotechnology
Keywords:
Genomic atlas 2.0; advanced genetic mapping; high-throughput sequencing; long-read sequencing technologies; spatial genomics; CRISPR technologies; integrative genomic mapping
Online: 8 March 2024 (03:57:26 CET)
CONCEPT PAPER
|
doi:10.20944/preprints202009.0723.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
Glycogen Storage Disease Type 1a, Glucose-6-phosphatase Catalytic Subunit (G6PC), Glucose-6-phosphatase (G6Pase), prime editing, mRNA delivery, CRISPR
Online: 30 September 2020 (08:05:17 CEST)
REVIEW
Subject:
Business, Economics And Management,
Economics
Keywords:
new plant engineering techniques (NPETs); new breeding techniques (NBTs); GMO; transgenic; genome editing; gene editing; cisgenic; CRISPR; RNAi; willingness to pay (WTP)
Online: 2 September 2021 (12:46:50 CEST)
HYPOTHESIS
|
doi:10.20944/preprints202010.0199.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
CRISPR interference; error-prone polymerase chain reaction; ribosomal proteins; ribosome; viability assay; Bacillus subtilis; Escherichia coli; sequence space; conformational space; mutational map
Online: 9 October 2020 (12:24:14 CEST)
ARTICLE
|
doi:10.20944/preprints202005.0001.v1
Subject:
Biology And Life Sciences,
Cell And Developmental Biology
Keywords:
CRISPR-Cas9; high-content screening (HCS); fluorescent-activated cell sorting (FACS); Parkinson's disease (PD); patient-derived iPS; single-cell clones; isogenic cell lines; SNCA; alpha-synuclein; A30P
Online: 2 May 2020 (11:20:20 CEST)
REVIEW
|
doi:10.20944/preprints201912.0385.v1
Subject:
Medicine And Pharmacology,
Cardiac And Cardiovascular Systems
Keywords:
dilated cardiomyopathy (DCM); hypertrophic cardiomyopathy (HCM); restrictive cardiomyopathy (RCM); arrhythmogenic right ventricular cardiomyopathy (ARVC); left ventricular non-compaction cardiomyopathy (LVNC); Duchenne muscular dystrophy; dystrophin; genome editing; CRISPR/Cas9; Cpf1 (Cas12a)
Online: 29 December 2019 (13:41:48 CET)