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Bayesian Elastic‑Net Cox Models for Time‑to‑Event Prediction: Application with Breast‑Cancer Cohort
Ersin Yılmaz
,Syed Ejaz Ahmed
,Dursun Aydın
Posted: 06 January 2026
The Philosophy of Marriage in India: A Tripartite Analysis of Contract, Institution, and Moral Bond
Shashank Tiwari
Posted: 06 January 2026
Graphene Oxide Nanoparticles Mediated Protective Effect Against the Ethanol Induced Gut-Liver Axis by Targeting miRNA-203a and miRNA-122
Hiral Aghara
,Teja Naveen Sata
,Prashsti Chadha
,Manali Patel
,Md Ismail
,Deeksha Rajput
,Pooja Gori
,Sriram Kanvah
,Manan Raval
,Senthil Kumar Venugopal
+1 authors
Posted: 06 January 2026
Large Language Models for Continual Relation Extraction
Sefika Efeoglu
,Adrian Paschke
,Sonja Schimmler
Posted: 06 January 2026
Quantum-Enhanced Adaptive Graph Convolutional Networks for Sentiment Representation Learning
Mingrui Rao
,Zihan Long
Posted: 06 January 2026
AEP-M: AI-Enhanced Anonymous E-Payment for Mobile Devices Using ARM Trust Zone and Divisible E-Cash
Vimal Teja Manne
Posted: 06 January 2026
Novel Silicone-Polyol Antifoam Emulsions: Impact on Foam Control and Physiology of Diverse Microbial Cultures
Mikhail Frolov
,Trofim A. Lozhkarev
,Elmira A. Vasilieva
,Leysan A. Vasileva
,Almaz A. Zagidullin
,Lucia Ya. Zakharova
,Galim A. Kungurov
,Natalia V. Trachtmann
,Shamil Z. Validov
The selection of an optimal antifoam is critical for efficient fermentation, as industrial agents often have detrimental side effects like growth inhibition, while some can enhance productivity. This study presents a rational approach to developing and screening novel silicone-polyol antifoam emulsions. A key finding was the discovery of selective antibacterial activity in agent 3L10, which strongly inhibited Gram-positive bacteria (especially Corynebacterium glutamicum) but not Gram-negative strains. This specificity, likely mediated by interaction with the mycolic acid layer of C. glutamicum, highlights the necessity for strain-specific antifoam testing. A comprehensive evaluation protocol—combining chemical design, cytotoxicity screening across diverse microorganisms, determination of minimum effective concentrations (MEC), and validation in model bioreactor fermentations—was established. Through this process, agent 6T80 was identified as a promising candidate. It exhibited low MEC, high emulsion stability, no cytotoxicity, and did not impair growth or recombinant protein production in B. subtilis or P. putida fermentations. The study concludes that agent 6T80 is suitable for further application in processes involving Gram-negative and certain Gram-positive hosts, whereas agent 3L10 serves as a valuable tool for studying surfactant-membrane interactions. The developed methodology enables the targeted selection of highly efficient and biocompatible antifoams for specific biotechnological processes.
The selection of an optimal antifoam is critical for efficient fermentation, as industrial agents often have detrimental side effects like growth inhibition, while some can enhance productivity. This study presents a rational approach to developing and screening novel silicone-polyol antifoam emulsions. A key finding was the discovery of selective antibacterial activity in agent 3L10, which strongly inhibited Gram-positive bacteria (especially Corynebacterium glutamicum) but not Gram-negative strains. This specificity, likely mediated by interaction with the mycolic acid layer of C. glutamicum, highlights the necessity for strain-specific antifoam testing. A comprehensive evaluation protocol—combining chemical design, cytotoxicity screening across diverse microorganisms, determination of minimum effective concentrations (MEC), and validation in model bioreactor fermentations—was established. Through this process, agent 6T80 was identified as a promising candidate. It exhibited low MEC, high emulsion stability, no cytotoxicity, and did not impair growth or recombinant protein production in B. subtilis or P. putida fermentations. The study concludes that agent 6T80 is suitable for further application in processes involving Gram-negative and certain Gram-positive hosts, whereas agent 3L10 serves as a valuable tool for studying surfactant-membrane interactions. The developed methodology enables the targeted selection of highly efficient and biocompatible antifoams for specific biotechnological processes.
Posted: 06 January 2026
Comparative Evaluation of DeepLabCut Convolutional Neural Network Architectures for High-Precision Markerless Tracking in the Mouse Staircase Test
Valentin Fernandez
,Landoline Bonnin
,Christine Fernandez-Maloigne
Posted: 06 January 2026
Workflow for Buried Pipe Detection and Geotechnical Characterization in Conductive Clay–Marl Environments
Pedro Carrasco-García
,Arturo Zevallos
,Javier Carrasco-García
,Juan Ignacio Canelo-Perez
Posted: 06 January 2026
A Novel anti-Cadherin 19 Monoclonal Antibody (Ca19Mab-8) for Flow Cytometry, Western Blotting, and Immunohistochemistry
Guanjie Li
,Hiroyuki Suzuki
,Mika K. Kaneko
,Yukinari Kato
Posted: 06 January 2026
Breast Cancer Patient Attitudes Towards Oncology Drug Costs in Ireland
Matthew Cronin
,Ruth Kieran
,Clara Steele
,Katie Cooke
,Seamus O’Reilly
Posted: 06 January 2026
Genome-Scale Modeling–Guided Metabolic Engineering Enables Heterologous Production of 3,4-amino-4-hydroxybenzoic Acid in Streptomyces thermoviolaceus
Togo Yamada
,Pamella Apriliana
,Prihardi Kahar
,Tomoya Kobayashi
,Yutaro Mori
,Chiaki Ogino
Posted: 06 January 2026
User Perceptions of Virtual Consultations and Artificial Intelligence Assistance: A Mixed Methods Study
Pranavsingh Dhunnoo
,Karen McGuigan
,Vicky O'Rourke
,Bertalan Meskó
,Michael McCann
Posted: 05 January 2026
Zinc Nanoparticle Effects on the Green Leaf Volatiles and Phyllosphere Bacteriome in Capsicum annum Seedlings
García-Casillas Luis Alberto
,Reyes-Maldonado Oscar Kevin
,Sánchez-Fernández Rosa
,Zúñiga Mayo Víctor
,Zamudio-Ojeda Adalberto
,Lomelí-Rosales Diego Alberto
,Cortez-Álvarez César Ricardo
,Rebeca Escutia Gutiérrez
,Guevara-Martínez José Santiago
,Velázquez-Juárez Gilberto
The use of zinc oxide nanoparticles (ZnONPs) in agriculture has increased due to their biostimulant potential; however, their effects on plant chemical communication and associated microbial communities are still poorly understood. This study presents a multi-perspective analysis contrasting the effects of ZnONPs with those of conventional ZnO (Bulk) on Capsicum annuum seedlings grown in a substrate with concentrations of 50 and 500 mg kg⁻¹. The results reveal that, at high doses, the bulk material (B500) generated a higher foliar accumulation of zinc (128.7 mg kg⁻¹) than ZnONPs (NP500, 119.7 mg kg⁻¹), a phenomenon attributed to the agglomeration of nanoparticles in the soil matrix, which limits their root absorption. At the physiological level, a critical divergence was observed: while bulk ZnO stimulated the activity of the enzyme superoxide dismutase (SOD), ZnONPs caused severe inhibition of the same (93% reduction), compromising the enzymatic antioxidant machinery and forcing the plant to rely on non-enzymatic mechanisms, such as an increase in total phenols. The volatilomic profile revealed a specific metabolic disturbance induced by ZnONPs in the green leaf volatiles (GLV) pathway. A significant accumulation of hexanal and suppression of hexanol and hexyl acetate were detected, suggesting that the nanomaterial inhibited alcohol dehydrogenase (ADH). In addition, ZnONPs suppressed the emission of methyl salicylate (MeSA)—a key messenger in acquired systemic resistance—whereas the Bulk treatment increased its abundance to 41.7%. Finally, metagenomic analysis indicated that zinc stress restructured the phyllosphere microbiota, promoting the proliferation of Actinobacteria and eliminating sensitive taxa such as Spirochaetes. Taken together, these findings demonstrate that ZnONPs act as multifactorial stressors that not only alter internal metabolism but also silence chemical communication and remodel plant ecology.
The use of zinc oxide nanoparticles (ZnONPs) in agriculture has increased due to their biostimulant potential; however, their effects on plant chemical communication and associated microbial communities are still poorly understood. This study presents a multi-perspective analysis contrasting the effects of ZnONPs with those of conventional ZnO (Bulk) on Capsicum annuum seedlings grown in a substrate with concentrations of 50 and 500 mg kg⁻¹. The results reveal that, at high doses, the bulk material (B500) generated a higher foliar accumulation of zinc (128.7 mg kg⁻¹) than ZnONPs (NP500, 119.7 mg kg⁻¹), a phenomenon attributed to the agglomeration of nanoparticles in the soil matrix, which limits their root absorption. At the physiological level, a critical divergence was observed: while bulk ZnO stimulated the activity of the enzyme superoxide dismutase (SOD), ZnONPs caused severe inhibition of the same (93% reduction), compromising the enzymatic antioxidant machinery and forcing the plant to rely on non-enzymatic mechanisms, such as an increase in total phenols. The volatilomic profile revealed a specific metabolic disturbance induced by ZnONPs in the green leaf volatiles (GLV) pathway. A significant accumulation of hexanal and suppression of hexanol and hexyl acetate were detected, suggesting that the nanomaterial inhibited alcohol dehydrogenase (ADH). In addition, ZnONPs suppressed the emission of methyl salicylate (MeSA)—a key messenger in acquired systemic resistance—whereas the Bulk treatment increased its abundance to 41.7%. Finally, metagenomic analysis indicated that zinc stress restructured the phyllosphere microbiota, promoting the proliferation of Actinobacteria and eliminating sensitive taxa such as Spirochaetes. Taken together, these findings demonstrate that ZnONPs act as multifactorial stressors that not only alter internal metabolism but also silence chemical communication and remodel plant ecology.
Posted: 05 January 2026
GuardianMind: A Multi-Modal Enhanced Large Language Model for Smart City Emergency Response
Tianrui Zhao
,Linyu Wu
Posted: 05 January 2026
Understanding ESG Ratings: A Systematic Literature Review of Methodologies, Divergences, Impact, Standardization, Disclosure Quality, Technology, and Global Financial Implications (2020–2025)
Hannan Vilchis Zubizarreta
,Delfor Tito Aquino
Purpose: This paper aims to systematically synthesize academic research published between 2020 and 2025 that investigates environmental, social, and governance (ESG) ratings and scores, with a focus on their methodologies, comparative performance, and impact on firm outcomes. Design/methodology/approach: A systematic literature review (SLR) was conducted using the Lens.org scholarly database. A structured title search retrieved 334 open access journal articles published between 2020 and May 2025 containing the terms "ESG Score", "ESG Rating", or "ESG Rater". The PRISMA 2020 protocol guided the selection and screening process. Findings: The literature exhibits growing concern about the divergence among ESG ratings, the methodological opacity of rating providers, and the variable financial implications of ESG scores. Common themes include score disagreements, rating agency biases, and emerging models for standardizing ESG assessments. Originality: This review provides the most up-to-date synthesis of ESG rating literature, focusing exclusively on articles explicitly addressing ESG ratings or scores in their titles. It contributes clarity to the fragmented ESG measurement space by organizing findings around key methodological and evaluative debates.
Purpose: This paper aims to systematically synthesize academic research published between 2020 and 2025 that investigates environmental, social, and governance (ESG) ratings and scores, with a focus on their methodologies, comparative performance, and impact on firm outcomes. Design/methodology/approach: A systematic literature review (SLR) was conducted using the Lens.org scholarly database. A structured title search retrieved 334 open access journal articles published between 2020 and May 2025 containing the terms "ESG Score", "ESG Rating", or "ESG Rater". The PRISMA 2020 protocol guided the selection and screening process. Findings: The literature exhibits growing concern about the divergence among ESG ratings, the methodological opacity of rating providers, and the variable financial implications of ESG scores. Common themes include score disagreements, rating agency biases, and emerging models for standardizing ESG assessments. Originality: This review provides the most up-to-date synthesis of ESG rating literature, focusing exclusively on articles explicitly addressing ESG ratings or scores in their titles. It contributes clarity to the fragmented ESG measurement space by organizing findings around key methodological and evaluative debates.
Posted: 05 January 2026
Phase Transitions in Disordered LC Systems: A Classical Analog of Quantum Transitions
Valeriy Arkhincheev
Posted: 05 January 2026
Reframing ESG for Urban Planning: A Systematic Review of Spatial Governance, Investment Geographies, and Green Gentrification
Hannan Vilchis Zubizarreta
,Delfor Tito Aquino
Posted: 05 January 2026
Advanced Steering Stability Controls for Autonomous Articulated Vehicles Based on Differential Braking
Jesus Felez
Posted: 05 January 2026
Exploring ESG Dimensions in the Urban Context
Hannan Vilchis Zubizarreta
,Delfor Tito Aquino
This article provides a critical and thematically structured literature review of Environmental, Social, and Governance (ESG) urbanism as it intersects with the right to the city, green gentrification, affordable housing, public-private partnerships, and participatory governance. Drawing from over 100 peer-reviewed sources published between 2020 and 2025, the study examines how ESG frameworks are adopted, contested, and operationalized across diverse urban contexts. While ESG has emerged as a dominant paradigm in urban planning and real estate, the review reveals its frequent co-optation by market-driven agendas, which risk reproducing socio-spatial inequalities under the guise of sustainability. At the same time, the literature highlights promising alternatives rooted in environmental justice, multispecies ethics, legal reform, and community-led planning. The review advances the argument that ESG must be reframed not as a universal compliance model, but as a situated, justice-oriented framework capable of responding to the complex ecological and social realities of contemporary urbanization. By foregrounding relational governance, inclusive design, and equitable urban futures, the article contributes to an emerging research agenda that challenges technocratic sustainability and reclaims ESG as a transformative tool for spatial and environmental justice.
This article provides a critical and thematically structured literature review of Environmental, Social, and Governance (ESG) urbanism as it intersects with the right to the city, green gentrification, affordable housing, public-private partnerships, and participatory governance. Drawing from over 100 peer-reviewed sources published between 2020 and 2025, the study examines how ESG frameworks are adopted, contested, and operationalized across diverse urban contexts. While ESG has emerged as a dominant paradigm in urban planning and real estate, the review reveals its frequent co-optation by market-driven agendas, which risk reproducing socio-spatial inequalities under the guise of sustainability. At the same time, the literature highlights promising alternatives rooted in environmental justice, multispecies ethics, legal reform, and community-led planning. The review advances the argument that ESG must be reframed not as a universal compliance model, but as a situated, justice-oriented framework capable of responding to the complex ecological and social realities of contemporary urbanization. By foregrounding relational governance, inclusive design, and equitable urban futures, the article contributes to an emerging research agenda that challenges technocratic sustainability and reclaims ESG as a transformative tool for spatial and environmental justice.
Posted: 05 January 2026
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