REVIEW
|
doi:10.20944/preprints201905.0239.v1
Subject:
Medicine And Pharmacology,
Gastroenterology And Hepatology
Keywords:
oligonucleotide therapeutics; RNA interference; antisense; aptamer; decoy; pancreatic cancer
Online: 20 May 2019 (10:12:46 CEST)
REVIEW
|
doi:10.20944/preprints202106.0683.v1
Subject:
Medicine And Pharmacology,
Immunology And Allergy
Keywords:
Osteoarthritis; rheumatoid arthritis; synovitis; cartilage; bone; antisense; oligonucleotides; therapeutics.
Online: 28 June 2021 (16:01:16 CEST)
REVIEW
|
doi:10.20944/preprints202407.1712.v1
Subject:
Medicine And Pharmacology,
Neuroscience And Neurology
Keywords:
facioscapulohumeral muscular dystrophy (FSHD); DUX4; antisense oligonucleotides; RNAi; CRISPR; DNA aptamers; DNA decoys; targeted therapy; genetic therapy
Online: 22 July 2024 (11:53:34 CEST)
REVIEW
|
doi:10.20944/preprints202308.1964.v1
Subject:
Medicine And Pharmacology,
Neuroscience And Neurology
Keywords:
Antisense Oligonucleotides; Cell Penetrating Peptides; Delivery; DG9 peptide; Phosphorodi-amidate morpholino oligomers (PMO); Pip; R6G
Online: 29 August 2023 (09:48:58 CEST)
BRIEF REPORT
|
doi:10.20944/preprints202403.1465.v1
Subject:
Biology And Life Sciences,
Biology And Biotechnology
Keywords:
CUAD (contact unmodified antisense DNA) biotechnology; oligonucleotide insecticides; ribosomal RNA; DNA containment mechanism; plant protection
Online: 26 March 2024 (01:24:15 CET)
REVIEW
|
doi:10.20944/preprints202405.1955.v1
Subject:
Medicine And Pharmacology,
Medicine And Pharmacology
Keywords:
Antisense oligonucleotide; N-of-1; milasen; atipeksen; valeriasen; rare disease; exon skipping; splice switching; personalized medicine; muscular dystrophy
Online: 29 May 2024 (12:08:10 CEST)
ARTICLE
|
doi:10.20944/preprints202303.0389.v1
Subject:
Computer Science And Mathematics,
Artificial Intelligence And Machine Learning
Keywords:
antisense oligonucleotides; exon skipping; machine learning; ensemble learning; personalized medicine; n-of-1 therapy, splice switching; genetic disease; splicing; RNA
Online: 22 March 2023 (03:24:48 CET)
COMMUNICATION
|
doi:10.20944/preprints202312.0751.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
nucleic acid; antisense oligonucleotide; conjugation; sulfonyl azide; pentafluorophenyl and 4-nitrophenyl active esters; carboxylic acid group modification; pentafluorobenzyl
Online: 12 December 2023 (05:07:02 CET)
REVIEW
|
doi:10.20944/preprints201804.0322.v2
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
antisense oligonucleotides; antisense therapy; DNA insecticides; RNAi; medicine; agriculture; forestry
Online: 31 May 2018 (12:11:59 CEST)
CONCEPT PAPER
|
doi:10.20944/preprints202004.0412.v1
Subject:
Biology And Life Sciences,
Immunology And Microbiology
Keywords:
coronavirus; COVID-19; antisense oligonucleotide; ASO; LNA GapmeR
Online: 23 April 2020 (11:30:39 CEST)
ARTICLE
|
doi:10.20944/preprints202404.1315.v1
Subject:
Medicine And Pharmacology,
Neuroscience And Neurology
Keywords:
spinal muscular atrophy; neuromuscular disease; nusinersen; antisense oligonucleotide; pediatrics
Online: 19 April 2024 (08:05:23 CEST)
REVIEW
|
doi:10.20944/preprints202103.0050.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
antisense; antibiotic resistance; RNase P; RNase H; nucleotide analogs
Online: 2 March 2021 (09:17:47 CET)
ARTICLE
|
doi:10.20944/preprints202005.0432.v1
Subject:
Biology And Life Sciences,
Food Science And Technology
Keywords:
antisense; HIV-1 nef; stop codon readthrough; selenium; thioredoxin reductase
Online: 26 May 2020 (13:16:09 CEST)
ARTICLE
|
doi:10.20944/preprints202407.0557.v1
Subject:
Medicine And Pharmacology,
Internal Medicine
Keywords:
Familial Chylomicronemia Syndrome; severe hypertriglyceridemia; Volanesorsen; antisense oligonucleotide; Platelets; thrombin generation
Online: 8 July 2024 (09:10:30 CEST)
ARTICLE
|
doi:10.20944/preprints202302.0033.v1
Subject:
Medicine And Pharmacology,
Pathology And Pathobiology
Keywords:
Neuromuscular disorder; NCALD; SMA; SMN2; Antisense oligonucleotide; Genetic modifier; Therapy; hiPSCs
Online: 2 February 2023 (07:54:05 CET)
CONCEPT PAPER
|
doi:10.20944/preprints202212.0334.v1
Subject:
Biology And Life Sciences,
Agricultural Science And Agronomy
Keywords:
essential oil plants; antisense oligoilators; secondary metabolites; oligonucleotide insecticides; green agriculture
Online: 19 December 2022 (09:48:52 CET)
ARTICLE
|
doi:10.20944/preprints202201.0173.v1
Subject:
Medicine And Pharmacology,
Neuroscience And Neurology
Keywords:
γ-synuclein; AAV vector; antisense oligonucleotide; cognitive dysfunction; dopamine; motor deficits
Online: 12 January 2022 (14:27:18 CET)
REVIEW
|
doi:10.20944/preprints202112.0273.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
RNA therapeutics; cardiovascular disease; mRNA therapeutics; siRNA therapeutics; antisense oligonucleotide therapeutics
Online: 16 December 2021 (14:07:05 CET)
REVIEW
|
doi:10.20944/preprints201906.0032.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
nucleic acids analogs, antisense, CRISPR, antibiotic resistance, myotonic dystrophy, cholesterol, hematologic malignancy,
Online: 5 June 2019 (08:11:12 CEST)
REVIEW
|
doi:10.20944/preprints202309.1728.v1
Subject:
Medicine And Pharmacology,
Medicine And Pharmacology
Keywords:
Fibrodysplasia ossificans progressiva (FOP); heterotopic ossification; bone morphogenetic proteins (BMPs); ACVR1; antisense therapy
Online: 26 September 2023 (05:27:10 CEST)
BRIEF REPORT
|
doi:10.20944/preprints202309.1527.v1
Subject:
Medicine And Pharmacology,
Neuroscience And Neurology
Keywords:
spinal muscular atrophy; SMN1 gene; SMN2 gene; nuclear gems; antisense oligonucleotides; splicing correction.
Online: 22 September 2023 (09:19:28 CEST)
REVIEW
|
doi:10.20944/preprints202307.1409.v1
Subject:
Biology And Life Sciences,
Life Sciences
Keywords:
spinal and bulbar muscular atrophy; antisense therapy; oligonucleotide; splice switching; mRNA knockdown; androgen receptor; AR45
Online: 20 July 2023 (09:53:18 CEST)
REVIEW
|
doi:10.20944/preprints202405.0274.v1
Subject:
Medicine And Pharmacology,
Neuroscience And Neurology
Keywords:
cell-penetrating peptides (CPP); antisense oligonucleotides (ASO); spinal muscular atrophy (SMA); delivery; phosphorodiamidate morpholino oligomers (PMO); DG9
Online: 6 May 2024 (09:54:35 CEST)
ARTICLE
|
doi:10.20944/preprints202402.0961.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
Somatic embryogenesis; coffee; Coffea arabica L.; transcriptome analysis; PPI network; trehalase antisense; osmotic medium; SE-RD29TAS; SE-WT
Online: 19 February 2024 (14:51:10 CET)
REVIEW
|
doi:10.20944/preprints202302.0429.v1
Subject:
Medicine And Pharmacology,
Dermatology
Keywords:
RNA therapeutics; skin; mRNA therapeutics; siRNA therapeutics; antisense oligonucleotide ther-apeutics; ASO; melanoma; hypertrophic scars; wound healing; dermatology
Online: 27 February 2023 (01:53:06 CET)
ARTICLE
|
doi:10.20944/preprints202303.0167.v1
Subject:
Biology And Life Sciences,
Biology And Biotechnology
Keywords:
antisense oligonucleotides; exon skipping; machine learning; ensemble learning; personalized medicine; n-of-1 therapy; splice switching; genetic disease; splicing; RNA
Online: 9 March 2023 (04:43:55 CET)
REVIEW
|
doi:10.20944/preprints202007.0744.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
long non-coding RNA (lncRNA); RNA polymerase II (RNAPII) transcription; gene regulation; tandem transcriptional interference (tTI); antisense transcription; DNA processing
Online: 31 July 2020 (10:47:08 CEST)
REVIEW
|
doi:10.20944/preprints202402.1738.v1
Subject:
Biology And Life Sciences,
Neuroscience And Neurology
Keywords:
Antisense oligonucleotides (ASOs); motor neuron diseases; spinal muscular atrophy; amyotrophic lateral sclerosis; spinal and bulbar muscular atrophy; innovative therapy; nusinersen; tofersen; clinical trals
Online: 1 March 2024 (03:10:14 CET)
ARTICLE
|
doi:10.20944/preprints201902.0172.v4
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
RNA-dependent amplification of mammalian mRNA; physiologically occurring intracellular PCR, iPCR; RNA-dependent RNA polymerase, RdRp; chimeric RNA; sense-strand RNA; antisense-strand RNA
Online: 12 June 2019 (12:21:59 CEST)
REVIEW
|
doi:10.20944/preprints202406.2068.v1
Subject:
Biology And Life Sciences,
Neuroscience And Neurology
Keywords:
spinal muscular atrophy (SMA); survival of motor neuron 1 (SMN1); SMN2; SMN protein; antisense oligonucleotide (ASO); nusinersen; gene therapy; onasemnogene; risdiplam; small molecule; combination therapy
Online: 29 June 2024 (06:33:01 CEST)