Subject:
Medicine And Pharmacology,
Other
Keywords:
Reproducibility, Mathematical Modeling, Multiscale Modeling, Translational Research, Biomedical Research, Experimental Biology, Clinical Research Article Type: Essay
Online: 23 May 2018 (16:18:52 CEST)
REVIEW
|
doi:10.20944/preprints201804.0009.v1
Subject:
Biology And Life Sciences,
Animal Science, Veterinary Science And Zoology
Keywords:
feline immunodeficiency virus; FIV; human immunodeficiency virus; HIV; animal models, opportunistic disease, lentiviral pathogenesis; molecular biology
Online: 2 April 2018 (07:54:28 CEST)
COMMUNICATION
|
doi:10.20944/preprints202312.0024.v1
Subject:
Biology And Life Sciences,
Life Sciences
Keywords:
Neotropics; Northern Triangle of Central America; phenology; tropical dry forests; urban biology; vector ecology; vector-borne disease.
Online: 1 December 2023 (04:04:46 CET)
ARTICLE
|
doi:10.20944/preprints202310.1264.v1
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
Glioblastoma; Fibronectin; Biomarkers; Cell signaling; In vitro techniques; Survivin; STAT3 transcription factor; PTEN protein; Prognosis; Computational biology
Online: 19 October 2023 (10:33:20 CEST)
ARTICLE
|
doi:10.20944/preprints202104.0475.v1
Subject:
Medicine And Pharmacology,
Immunology And Allergy
Keywords:
drug repurposing; virtual screening; multiscale; multitargeting; polypharmacology; computational biology; drug repositioning; structural bioinformatics; molecular docking; proteomic signature
Online: 19 April 2021 (12:22:05 CEST)
ARTICLE
|
doi:10.20944/preprints202101.0360.v3
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
DNA alphabets, genomes, percentages of n-plets, binary-oppositions, tensor family of matrices, tetra-groupings, quantum biology, algebraic holography.
Online: 23 June 2021 (11:49:51 CEST)
CONCEPT PAPER
|
doi:10.20944/preprints202008.0574.v2
Subject:
Biology And Life Sciences,
Biology And Biotechnology
Keywords:
evolution; evotype; engineering theory; genotype-phenotype maps; directed evolution; selection; synthetic biology; bioengineering; evolvability; self-adaptive systems
Online: 9 December 2020 (10:51:51 CET)
REVIEW
|
doi:10.20944/preprints202011.0302.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
evolutionary cell biology; evo-devo; animal origins; choanoflagellates; history of science; Haeckel; Metchnikoff; Blastaea; origin of multicellularity
Online: 10 November 2020 (11:18:25 CET)
ARTICLE
|
doi:10.20944/preprints201812.0018.v2
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
colorectal cancer; differentially expressed genes; biomarkers; protein-protein interaction; reporter biomolecules; candidate drugs; systems biology; drug repositioning
Online: 29 December 2018 (07:05:05 CET)
ARTICLE
|
doi:10.20944/preprints201811.0183.v2
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
sequencing technologies; NGS; genome research; genome assembly; variant calling; RNA-Seq; transcriptome assembly; bioinformatics; molecular biology; education
Online: 13 November 2018 (10:22:06 CET)
ARTICLE
|
doi:10.20944/preprints201808.0330.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
ancestry of orthogs, ancestry of gene families; gene genealogy; FUCA; LUCA; origins of life; gradualism; evolutionary biology
Online: 18 August 2018 (08:24:09 CEST)
REVIEW
|
doi:10.20944/preprints202401.0419.v1
Subject:
Biology And Life Sciences,
Neuroscience And Neurology
Keywords:
Neurodegeneration; inflammation; cancer; Parkinson's Disease; neuron; cell biology; interleukins; disease progression; genetic and somatic mutations; double hit hypothesis
Online: 4 January 2024 (14:13:35 CET)
ARTICLE
|
doi:10.20944/preprints202312.0422.v1
Subject:
Biology And Life Sciences,
Other
Keywords:
Synthetic Biology; Origin of Life; Maxwell’ s Demons; Turing Patterns; Biological Memory 12 Formation; Synthetic Life Forms
Online: 6 December 2023 (12:27:33 CET)
ARTICLE
|
doi:10.20944/preprints202212.0572.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
formate dehydrogenase; Candida boidinii; protein engineering; X-ray crystallography; structural biology; structural dynamics; Turkish Light Source; Turkish DeLight.
Online: 30 December 2022 (08:03:07 CET)
REVIEW
Subject:
Biology And Life Sciences,
Biology And Biotechnology
Keywords:
natural products; biosynthetic gene clusters; synthetic biology; genome mining strategies; modification strategies; design-build-test-learn (DBTL) cycle
Online: 8 October 2021 (09:10:02 CEST)
ARTICLE
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
CA3-CA1 synapses; NMDA; AMPA; systems biology; multiscale modeling; synaptic plasticity; long term potentiation; long term depression; hippocampus
Online: 8 January 2021 (13:17:31 CET)
REVIEW
|
doi:10.20944/preprints202001.0155.v1
Subject:
Biology And Life Sciences,
Immunology And Microbiology
Keywords:
Tumor microenvironment; tumor stroma; cancer-associated fibroblasts; heterogeneity; biomarkers; cancer; The Cancer Genome Atlas; gene expression; computational biology
Online: 15 January 2020 (12:56:44 CET)
REVIEW
|
doi:10.20944/preprints201904.0206.v1
Subject:
Biology And Life Sciences,
Biophysics
Keywords:
helial-mesenchymal transition; EMT spectrum; hybrid epithelial/mesenchymal phenotypes; CTC clusters; stemness; immune suppression; EMT metrics; systems biology
Online: 18 April 2019 (08:02:27 CEST)
ARTICLE
|
doi:10.20944/preprints201804.0339.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
myocardial infarction; heart attack; gene set enrichment analysis; protein-protein interaction network; bioinformatics; systems biology; in silico study
Online: 26 April 2018 (10:22:31 CEST)
ARTICLE
|
doi:10.20944/preprints202310.1614.v1
Subject:
Engineering,
Industrial And Manufacturing Engineering
Keywords:
central dogma of molecular biology; DNA-based computing; smart manufacturing, biologicalization of manufacturing; image processing; pattern recognition; sensor signals
Online: 25 October 2023 (11:46:25 CEST)
REVIEW
|
doi:10.20944/preprints202305.2170.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
DNA damage; base excision repair; nucleotide excision repair; UV-DDB; chromatin; nucleosome; DNA glycosylases; single molecule; cell biology; biochemistry
Online: 31 May 2023 (05:44:02 CEST)
COMMUNICATION
|
doi:10.20944/preprints202207.0329.v1
Subject:
Engineering,
Bioengineering
Keywords:
in-space biomanufacturing; space synthetic biology; space bioprocess engineering; biological life-support systems; in situ resource utilization; circular economy
Online: 21 July 2022 (11:01:29 CEST)
REVIEW
|
doi:10.20944/preprints202012.0044.v1
Subject:
Biology And Life Sciences,
Anatomy And Physiology
Keywords:
Integrins; Tumor Microenvironment; Drug Resistance; Migration; Metastasis; Solid Tumors; The Cancer Genome Atlas; Gene Expression; Computational Biology; Therapeutic Targeting
Online: 1 December 2020 (18:26:11 CET)
ARTICLE
|
doi:10.20944/preprints202306.1285.v1
Subject:
Biology And Life Sciences,
Ecology, Evolution, Behavior And Systematics
Keywords:
standard lagrangian; calculus of variation; hamiltonian; Lagrangian formalism; population dynamics; Euler-Lagrange equation; mathematical biology; nonlinear dynamical systems; ecological model
Online: 19 June 2023 (04:30:37 CEST)
REVIEW
|
doi:10.20944/preprints202305.2262.v1
Subject:
Biology And Life Sciences,
Agricultural Science And Agronomy
Keywords:
anise; basil; borage; cilantro; chamomile; seed biology; seed production; seed germination; seed dormancy; seed priming; seedling establishment; anatomy and germination
Online: 31 May 2023 (14:25:24 CEST)
ARTICLE
|
doi:10.20944/preprints202208.0107.v1
Subject:
Physical Sciences,
Biophysics
Keywords:
biology; symmetry; asymmetry; periodic ordering; aperiodic ordering; Curie principle; information; Landauer principle; continuous measure of symmetry; Shannon measure of symmetry.
Online: 4 August 2022 (08:54:04 CEST)
REVIEW
|
doi:10.20944/preprints202208.0065.v1
Subject:
Biology And Life Sciences,
Biology And Biotechnology
Keywords:
EPR spectroscopy; double electron electron resonance; FRET; ensemble model; intrinsic disorder; structural biology; site-directed spin labelling; molecular force fields
Online: 2 August 2022 (11:21:32 CEST)
REVIEW
|
doi:10.20944/preprints202107.0359.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
Artificial intelligence; Core set; Climate change; Nitrogen use efficiency; Omic approaches; Plant genetic resources; Stress; Systems biology; Water use efficiency
Online: 15 July 2021 (13:28:14 CEST)
ARTICLE
|
doi:10.20944/preprints202102.0135.v1
Subject:
Computer Science And Mathematics,
Applied Mathematics
Keywords:
algorithmic information theory; universal distribution; Kolmogorov complexity; quantum algorithms; quantum circuit model; quantum Turing machine; genomics; viral genomics; meta-biology
Online: 4 February 2021 (12:04:02 CET)
Subject:
Biology And Life Sciences,
Life Sciences
Keywords:
life; gene; species; molecular biology; evolution; natural selection; pregnancy; origins; common ancestry; maturation; relativity; time; religion; philosophy; free will; material; immaterial
Online: 18 April 2024 (13:40:39 CEST)
Subject:
Social Sciences,
Psychology
Keywords:
spiritual intelligence; biology of knowledge; developmental psychology; logical analysis; neurology; neuroscience; transpersonal psychology; Howard Gardner; theory of multiple intelligences; cognitive sciences
Online: 22 October 2021 (08:16:01 CEST)
TECHNICAL NOTE
|
doi:10.20944/preprints202012.0296.v1
Subject:
Computer Science And Mathematics,
Algebra And Number Theory
Keywords:
Systems Biology; Numerical Solver; Java™; API Library; SBML; SED-ML; OMEX; Constraint-Based Modeling; Stochastic Simulation; Ordinary Differential Equation Systems
Online: 11 December 2020 (19:41:58 CET)
ARTICLE
|
doi:10.20944/preprints201911.0330.v1
Subject:
Biology And Life Sciences,
Virology
Keywords:
complex systems; DNB; phase transitions; plant-virus interaction; Potyvirus; protein-protein interaction networks; response to infection; systems biology; Tobacco etch virus
Online: 27 November 2019 (04:42:28 CET)
COMMUNICATION
|
doi:10.20944/preprints202210.0383.v2
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
structural biology; organelles; Golgi Apparatus (GA); Parkinson’s disease (PD); cryo-ET; alpha-synuclein; neurodegenerative diseases; soft X-ray tomography (SXT); cancer; NDDs
Online: 5 December 2022 (02:27:26 CET)
REVIEW
Subject:
Biology And Life Sciences,
Anatomy And Physiology
Keywords:
epithelial mesenchymal plasticity (EMP); epithelial mesenchymal transition (EMT); mesenchymal epithelial transition (MET); E/M Hybrid; partial EMT; computational biology; mathematical modeling; cancer
Online: 10 February 2021 (15:04:19 CET)
CONCEPT PAPER
|
doi:10.20944/preprints202104.0686.v1
Subject:
Biology And Life Sciences,
Anatomy And Physiology
Keywords:
H2O networks; Aqua biomolecule complexes; Thermodynamic mechanism; “Aquamoleculosome"; Entropic systems biology; Self-organized criticality (SOC); Self-organization triggering factor (SOTF); Bioinformatics of aquamoleculomics.
Online: 26 April 2021 (20:02:20 CEST)
ARTICLE
|
doi:10.20944/preprints202101.0441.v1
Subject:
Computer Science And Mathematics,
Algebra And Number Theory
Keywords:
Quantum Similarity; DNA; Molecular Biology; Meticodes; response variance; object set reference; Bioinformatics; Computational Physics; Computational Models; Mathematics; Probability; Statistics; Comparative Modeling; Biostatics; Biostatistics
Online: 22 January 2021 (11:35:18 CET)
REVIEW
|
doi:10.20944/preprints202209.0487.v2
Subject:
Medicine And Pharmacology,
Cardiac And Cardiovascular Systems
Keywords:
Immunology; innate immunity; immunogenetics; noncoding genome; tRNA biology; evolutionary genetics (list 3-10 specific to the article yet reasonably common within the subject discipline)
Online: 1 November 2022 (09:55:10 CET)
ARTICLE
|
doi:10.20944/preprints202204.0051.v1
Subject:
Social Sciences,
Political Science
Keywords:
Biological and Toxin Weapons Convention; Biological Weapons Convention; BWC; biological weapons; verification; nonproliferation; nonproliferation policy; arms control; disarmament; weapons of mass destruction; WMD; biology
Online: 7 April 2022 (03:51:48 CEST)
ARTICLE
|
doi:10.20944/preprints202103.0568.v1
Subject:
Social Sciences,
Psychology
Keywords:
Voice and sexual orientation; Human sex pheromones; Evolution of sexual orientation; Development of sexual orientation; Puberty; Causes of sexual orientation; Biology of sexual orientation
Online: 23 March 2021 (12:47:18 CET)
REVIEW
|
doi:10.20944/preprints202402.1729.v2
Subject:
Biology And Life Sciences,
Cell And Developmental Biology
Keywords:
epithelial– mesenchymal transition, mesenchymal-epithelial transition, endothelial-mesenchymal transition, epithelial state, mesenchymal state, controversy, developmental biology, fibrosis, cancer, neural stemness, tumorigenicity, pluripotency
Online: 16 April 2024 (15:50:00 CEST)
ARTICLE
Subject:
Biology And Life Sciences,
Immunology And Microbiology
Keywords:
NK cell biology; NK cell subsets; NK activating receptors; cell adhesion molecules; granule polarization; cytotoxicity assay; cis interactions; trogocytosis; NK cell degranulation; NK-Based Immunotherapies
Online: 14 February 2020 (03:13:05 CET)
REVIEW
|
doi:10.20944/preprints202006.0078.v1
Subject:
Biology And Life Sciences,
Immunology And Microbiology
Keywords:
COVID-19; vaccine; vaccine development; vaccine discovery; systems biology; machine learning; platform technologies; adjuvants; smart clinical trials; human genetics; regulatory convergence; real world evidence; vaccines safety
Online: 7 June 2020 (10:11:02 CEST)
REVIEW
|
doi:10.20944/preprints202102.0409.v1
Subject:
Social Sciences,
Education
Keywords:
Professional development for scientists; tenure-track faculty; tenure; professoriate; professional development practicum; professional development experiential learning; Accomplishing Career Transitions; American Society for Cell Biology; Minorities Affairs Committee
Online: 18 February 2021 (10:43:19 CET)
HYPOTHESIS
|
doi:10.20944/preprints202003.0134.v1
Subject:
Social Sciences,
Gender And Sexuality Studies
Keywords:
nature and nurture of sexual orientation; development of sexual orientation; Puberty; Voice and sexual orientation; causes of sexual orientation; MGN and sexual orientation; biology of sexual orientation
Online: 8 March 2020 (05:11:50 CET)
ARTICLE
|
doi:10.20944/preprints202205.0096.v1
Subject:
Biology And Life Sciences,
Plant Sciences
Keywords:
plant 3D imaging; Zea mays L.; vascular system; internodes; nodal plexus; contrast-enhanced magnetic resonance imaging; laser scanning microscopy; lab-on-a-chip; particle image velocimetry; systems biology
Online: 9 May 2022 (03:22:20 CEST)
COMMUNICATION
|
doi:10.20944/preprints202401.0231.v1
Subject:
Public Health And Healthcare,
Other
Keywords:
Explainable AI (XAI); Interdisciplinary Conferences; GLBIO ISCB; Healthcare Informatics; Computational Biology; AI Ethics in Healthcare; Algorithmic Transparency; AI in Medical Decision Making; Patient-Centered AI; Regulatory Aspects of Healthcare AI
Online: 3 January 2024 (10:05:19 CET)
ARTICLE
|
doi:10.20944/preprints201812.0064.v1
Subject:
Biology And Life Sciences,
Other
Keywords:
combinatorial search forest; sensitivity analysis; support vector ranking algorithm; unknown biological hypotheses; Wnt pathway; PORCN-WNT inhibitors; ETC-1922159; Sobol indices; Hilbert Schmidt independence criterion indices (HSIC); F-divergence (Fdiv); systems biology
Online: 5 December 2018 (07:52:17 CET)
ARTICLE
|
doi:10.20944/preprints202404.0851.v1
Subject:
Social Sciences,
Political Science
Keywords:
Biological and Toxin Weapons Convention; Biological Weapons Convention; BWC; BTWC; biological weapons; verification; compliance; confidence-building measures; confidence building measures; CBM; CBMs; nonproliferation; nonproliferation policy; arms control; disarmament; weapons of mass destruction; WMD; biology
Online: 12 April 2024 (14:33:52 CEST)
REVIEW
|
doi:10.20944/preprints202210.0248.v1
Subject:
Biology And Life Sciences,
Aging
Keywords:
Trade-off of survival for reproduction; natural selection of aging; regulatory redundancy; aging’s individual benefit; regulatory molecular biology; Darwin’s dilemma; aging-reproduction trade-off; aging declines force of selection; master gene; holistic regulatory mechanism
Online: 18 October 2022 (04:36:09 CEST)
REVIEW
|
doi:10.20944/preprints202101.0304.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
Vascular Endothelial Growth Factors (VEGFs); VEGF-A; PlGF; VEGF-B; VEGF-C; VEGF-D; angiogenesis; lymphangiogenesis; CCBE1; proteases; ADAMTS3; plasmin; cathepsin D; KLK3; prostate-specific antigen (PSA); thrombin; wound healing; metastasis; proteolytic activation; vascular biology
Online: 18 January 2021 (09:05:58 CET)
HYPOTHESIS
|
doi:10.20944/preprints202104.0760.v1
Subject:
Medicine And Pharmacology,
Immunology And Allergy
Keywords:
Complementary and alternative medicine; Traditional Chinese medicine (TCM); Thermodynamic mechanism; Entropic systems biology; Self-organized criticality (SOC); Self-organization triggering factor (SOTF); Wuxing (five phases), Qi, Meridians (Jingluo); Acupuncture points; Chinese herbs; Aquamoleculomics; Modernization of TCM
Online: 28 April 2021 (17:12:29 CEST)