Version 1
: Received: 27 April 2021 / Approved: 28 April 2021 / Online: 28 April 2021 (17:12:29 CEST)
How to cite:
Nie, Z.; Nie, Y. Entropic Systems Biology: A Novel Thermodynamic Theory for the Modernization of Traditional Chinese Medicine. Preprints2021, 2021040760. https://doi.org/10.20944/preprints202104.0760.v1
Nie, Z.; Nie, Y. Entropic Systems Biology: A Novel Thermodynamic Theory for the Modernization of Traditional Chinese Medicine. Preprints 2021, 2021040760. https://doi.org/10.20944/preprints202104.0760.v1
Nie, Z.; Nie, Y. Entropic Systems Biology: A Novel Thermodynamic Theory for the Modernization of Traditional Chinese Medicine. Preprints2021, 2021040760. https://doi.org/10.20944/preprints202104.0760.v1
APA Style
Nie, Z., & Nie, Y. (2021). Entropic Systems Biology: A Novel Thermodynamic Theory for the Modernization of Traditional Chinese Medicine. Preprints. https://doi.org/10.20944/preprints202104.0760.v1
Chicago/Turabian Style
Nie, Z. and Yanming Nie. 2021 "Entropic Systems Biology: A Novel Thermodynamic Theory for the Modernization of Traditional Chinese Medicine" Preprints. https://doi.org/10.20944/preprints202104.0760.v1
Abstract
As a complementary and alternative medicine in the western countries for decades, traditional Chinese medicine (TCM) has been used for more than 2000 years in China. Because of the characteristics of the philosophical style and the unknown mechanism of action, TCM sometimes has been biasedly described as "fraught with pseudoscience". From the scientific basis of the systems biology, here we promoted a novel medical model called the entropic systems medicine which could be applied to scientize TCM in future. In entropic systems medicine, TCM and Western modern biomedicine target the different variables of the entropic system. For instance, while Western modern biomedicine directly targets the phenotypes and its SOCs of macrostates, TCM differently targets the microstates, entropy and entropic force to generate SOTFs gradually causing the differentiated syndromes to be slowly rearranged. The prerequisites to modernize TCM are the entropic systems biology having been well established so that the variables could be precisely monitored and mathematically calculated.
Keywords
Complementary and alternative medicine; Traditional Chinese medicine (TCM); Thermodynamic mechanism; Entropic systems biology; Self-organized criticality (SOC); Self-organization triggering factor (SOTF); Wuxing (five phases), Qi, Meridians (Jingluo); Acupuncture points; Chinese herbs; Aquamoleculomics; Modernization of TCM
Subject
Medicine and Pharmacology, Immunology and Allergy
Copyright:
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
