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Application of Selected Random Variable Distributions for Forecasting Wind Speed and Electricity Production in Order to Determine the Operation Strategy of Wind Power Plants
Sylwester Borowski
,Klaudiusz Migawa
,Andrzej Neubauer
,Paweł Krzaczek
Posted: 05 December 2025
Conventional NPK Fertilizer Rate Strategies for Improving Shoot Biomass in Pear Nursery Production
Adelina Venig
,Florin Stanica
,Adrian Peticilă
,Cristina Maria Maerescu
The production of pear (Pyrus communis L.) nurseries is essential to providing high-quality planting material for the establishment of a successful orchard. Thus, encouraging early vegetative growth and seedling vigor during the nursery period requires optimal fertilization. Under temperate continental circumstances in northwest Romania, this study assessed the impact of various NPK fertilizer rates on the shoot fresh weight of pear nursery trees. The study was carried out in 2025 using a factorial design with two Romanian cultivars (‘Napoca’ and ‘Monica’) and four fertilization treatments (N0P0K₀, N8P8K8, N16P16K16, and N₂₄P₂₄K₂₄), set up in a randomized block system with five replications. At progressively higher rates of 50, 100, and 150 kg ha⁻¹, a totally water-soluble 16–16–16 fertilizer was applied. At the conclusion of the growing season, the fresh weight of the shoots was measured. The accumulation of shoot biomass was significantly and gradually impacted by fertilization. The fresh weight of the shoots rose by 29%, 45%, and 59% as compared to the unfertilized control (0.42 kg tree⁻¹) under the treatments of N8P8K8, N₁₆P16K16, and N₂₄P₂₄K₂₄. There were no discernible cultivar-dependent variations at any fertilization level, and both cultivars showed almost equal growth responses. These findings show how strongly the growth of pear nursery shoots depends on the availability of NPK and offer helpful advice for maximizing fertilization techniques to enhance the quality of planting materials.
The production of pear (Pyrus communis L.) nurseries is essential to providing high-quality planting material for the establishment of a successful orchard. Thus, encouraging early vegetative growth and seedling vigor during the nursery period requires optimal fertilization. Under temperate continental circumstances in northwest Romania, this study assessed the impact of various NPK fertilizer rates on the shoot fresh weight of pear nursery trees. The study was carried out in 2025 using a factorial design with two Romanian cultivars (‘Napoca’ and ‘Monica’) and four fertilization treatments (N0P0K₀, N8P8K8, N16P16K16, and N₂₄P₂₄K₂₄), set up in a randomized block system with five replications. At progressively higher rates of 50, 100, and 150 kg ha⁻¹, a totally water-soluble 16–16–16 fertilizer was applied. At the conclusion of the growing season, the fresh weight of the shoots was measured. The accumulation of shoot biomass was significantly and gradually impacted by fertilization. The fresh weight of the shoots rose by 29%, 45%, and 59% as compared to the unfertilized control (0.42 kg tree⁻¹) under the treatments of N8P8K8, N₁₆P16K16, and N₂₄P₂₄K₂₄. There were no discernible cultivar-dependent variations at any fertilization level, and both cultivars showed almost equal growth responses. These findings show how strongly the growth of pear nursery shoots depends on the availability of NPK and offer helpful advice for maximizing fertilization techniques to enhance the quality of planting materials.
Posted: 05 December 2025
ExecMesh: Cryptographically Verifiable AI Provenance for Regulatory Compliance
Panagiotis Karmiris
Posted: 05 December 2025
An Architecture-Feature-Enhanced Decision Framework for Deep Learning-Based Prediction of Extreme and Imbalanced Precipitation
WenJiu Yu
,YingNa Sun
,ZhiCheng Yue
,ZhiNan Li
,YuJia Liu
Posted: 05 December 2025
Influence of Flexural Testing Parameters on the Flexural Response of Ultra-High Performance Concrete
Seong-Jin Woo
,In-Beom Park
,Dong-Hyun Kim
,Jun-Mo Yang
Posted: 05 December 2025
Neuromodulatory Fragility Is an Upstream Breakpoint for Alzheimer’s Disease Pathogenesis
Alfie Wearn
,Kate M. Onuska
,Taylor W. Schmitz
,Gary R. Turner
,R. Nathan Spreng
Sporadic Alzheimer’s disease (AD) is associated with numerous risk factors, yet its precise cause remains unclear. Here, we describe a novel framework for AD pathogenesis, whereby diverse risk factors converge on neuromodulatory subcortical systems to confer AD risk or resilience. Neuromodulatory projection neurons are uniquely fragile due to their large size, sparse myelination, and high basal metabolic demands. We propose that the increased prevalence of AD in older adult populations likely reflects a universal weakness within these projection systems, which is increasingly exposed as cellular transport and maintenance mechanisms deteriorate with age. The key insight of this ‘neuromodulatory fragility framework’ is that neuromodulatory system dysfunction is sufficient to explain both tau hyperphosphorylation and b-amyloid (Ab) plaque formation, the two pathological hallmarks of AD. We therefore predict that strengthening or preserving the endogenous functions of these systems in midlife represents the most effective strategy for preventing AD.
Sporadic Alzheimer’s disease (AD) is associated with numerous risk factors, yet its precise cause remains unclear. Here, we describe a novel framework for AD pathogenesis, whereby diverse risk factors converge on neuromodulatory subcortical systems to confer AD risk or resilience. Neuromodulatory projection neurons are uniquely fragile due to their large size, sparse myelination, and high basal metabolic demands. We propose that the increased prevalence of AD in older adult populations likely reflects a universal weakness within these projection systems, which is increasingly exposed as cellular transport and maintenance mechanisms deteriorate with age. The key insight of this ‘neuromodulatory fragility framework’ is that neuromodulatory system dysfunction is sufficient to explain both tau hyperphosphorylation and b-amyloid (Ab) plaque formation, the two pathological hallmarks of AD. We therefore predict that strengthening or preserving the endogenous functions of these systems in midlife represents the most effective strategy for preventing AD.
Posted: 05 December 2025
Temperature Difference and Gradience in PV Arrays: Impact of Array Height and Array Length
Akash Kumar
,Nijanth Kothandapani
,Sai Tatapudi
,Sagar Bhoite
,GovindaSamy TamizhMani
Posted: 05 December 2025
Rapid Mood Improvement and Transient Hypomania After Low-Dose Oral OTC Glutamatergic Augmentation in Post-TBI Bipolar Disorder
Ngo Cheung
Posted: 05 December 2025
Clinical Hurdles for Curcumin and Piperine Nanoparticles for Treatment of Prostate Cancer
Jibira Yakubu
,Oya Tagit
,Amit V. Pandey
Posted: 05 December 2025
Vegetation
Response to Interannual Precipitation Variability in High-Andean Wetlands of
Central Chile Using Sentinel-2, ERA5-Land, and UAV Imagery
Fabián Llanos-Bustos
,Leonardo Durán-Garate
,Waldo Pérez-Martínez
,Jesica Garrido-Leiva
,Benjamín Castro-Cancino
Posted: 05 December 2025
First Comprehensive Characterization and Ultrasound-Assisted Extraction Optimization of an Unexplored Amazonian Berry (Chondrodendron tomentosum): A Novel Source of Anthocyanins and Phenolic Compounds
Disbexy Huaman-Huaman
,Segundo G. Chavez
,Laydy Mena-Chacon
,Hans Minchán-Velayarce
,Ralph Rivera-Botonares
This is the first scientific report on the fruit characteristics of Chondrodendron tomentosum Ruiz & Pav. (Menispermaceae). Biometric and physicochemical parameters were characterized across three fruit ripening stages (green, turning, ripe). Additionally, proximate composition was determined in ripe fruits, and methanol concentration (25–75%), ultrasonic amplitude (30–70%), and time (1–15 min) were optimized using response surface methodology with a Box-Behnken design. During ripening, weight increased by +47.7% (3.89 to 5.74 g; p < 0.0001), TSS by +26.1% (7.00 to 8.83 °Brix), pH decreased by 32.0% (6.28 to 4.27), and acidity increased by 276% (0.25 to 0.94%). The quadratic models demonstrated high predictive accuracy (R² > 96.5%; p < 0.004). Optimal conditions (57% methanol, 70% amplitude, and 15 min) maximized total anthocyanin content (120.71 ± 1.89 mg cyanidin-3-glucoside/L), total phenols (672.46 ± 5.84 mg GAE/100 g), and antioxidant capacity (5857.55 ± 60.20 µmol Trolox/100 g) in ripe fruits. Anthocyanins were undetectable in green fruits, reaching 46.01 mg C3G/L in turning fruits and 120.71 mg/L in ripe fruits (162% higher than turning fruits). Principal component analysis (90.6% variance) revealed synchronized co-accumulation of anthocyanins and phenols, enhanced by vacuolar acidification. These results position ripe C. tomentosum fruits as a raw material for natural colorants, nutraceuticals, and functional foods.
This is the first scientific report on the fruit characteristics of Chondrodendron tomentosum Ruiz & Pav. (Menispermaceae). Biometric and physicochemical parameters were characterized across three fruit ripening stages (green, turning, ripe). Additionally, proximate composition was determined in ripe fruits, and methanol concentration (25–75%), ultrasonic amplitude (30–70%), and time (1–15 min) were optimized using response surface methodology with a Box-Behnken design. During ripening, weight increased by +47.7% (3.89 to 5.74 g; p < 0.0001), TSS by +26.1% (7.00 to 8.83 °Brix), pH decreased by 32.0% (6.28 to 4.27), and acidity increased by 276% (0.25 to 0.94%). The quadratic models demonstrated high predictive accuracy (R² > 96.5%; p < 0.004). Optimal conditions (57% methanol, 70% amplitude, and 15 min) maximized total anthocyanin content (120.71 ± 1.89 mg cyanidin-3-glucoside/L), total phenols (672.46 ± 5.84 mg GAE/100 g), and antioxidant capacity (5857.55 ± 60.20 µmol Trolox/100 g) in ripe fruits. Anthocyanins were undetectable in green fruits, reaching 46.01 mg C3G/L in turning fruits and 120.71 mg/L in ripe fruits (162% higher than turning fruits). Principal component analysis (90.6% variance) revealed synchronized co-accumulation of anthocyanins and phenols, enhanced by vacuolar acidification. These results position ripe C. tomentosum fruits as a raw material for natural colorants, nutraceuticals, and functional foods.
Posted: 05 December 2025
Beyond GDP: Reimagining Economic Value through Complexity, Relational Sociology, and Post-Growth Political Economy
Pitshou Moleka
Posted: 05 December 2025
Key Genomic Regions of Rice Cultivar GuiHeFeng and Its Derivatives Revealed by Genome-Wide Analysis
Yu-Zhi Chen
,Xin-Yu Hao
,Yuexiong Zhang
,Zeng-Feng Ma
,Chi Liu
,Xiao-Long Zhou
,Min-Yi Wei
,Bao-Xiang Qin
,Yong Yan
,Dahui Huang
Posted: 05 December 2025
Combined Effect of Plasma-Activated Water, Edible Coating, and Active Packaging on Shelf-Life of Cherry Tomatoes
Syed Mudabbar Hussain Shah
,Stefania Volpe
,Francesca Colonna
,Vincenzo Valentino
,Francesca De Filippis
,Elena Torrieri
,Silvana Cavella
Posted: 05 December 2025
Fractional Spectral Degeneracy Operators: Non-Local Phenomena and Anomalous Diffusion
Rômulo Damasclin Chaves dos Santos
,Jorge Henrique de Oliveira Sales
Posted: 05 December 2025
Crystal Structures of Novel Phenyl Fulgides
Yingchun Li
,Sameh Abdelwahed
,Nattamai Bhuvanesh
,Joseph Reibenspies
,Zhenhuan Yi
Posted: 05 December 2025
Biotechnological Potential of Native Thermophilic Microorgan-Isms for Creating a Soil Biomeliorant from Poultry Manure
Amiran Khabidovich Zanilov
,Zalim Islamovich Dudarov
,Milana Radievna Aznaeva
,Rustam Kharunovich Taov
,Dinara Gumarbievna Dudarova
Posted: 04 December 2025
Hybrid Offshore Wind and Wave Energy Systems: A Review
Haoyang Song
,Tongshun Yu
,Xin Tong
,Xuewen Zhao
,Zhenyu Zhang
,Zhixin Lun
,Li Wang
,Zeke Wang
Posted: 04 December 2025
Ecotoxicity of Plastic Nanoparticles in Quagga Mussels Dreissena bugensis
Chantale André
,François Gagné
Posted: 04 December 2025
Rethinking Emotion as Part of the Arousal Appraisal Model
Mario Passaro
Posted: 04 December 2025
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