Abstract: Background: Maternal mortality remains a major global health challenge, disproportionately affecting black and Indigenous women. Hypertensive disorders of pregnancy and postpartum hemorrhage are leading direct causes of maternal death. Artificial intelligence (AI) tools have emerged as potential strategies for predicting these complications, yet concerns persist about their equity and validation across racial groups. Methods: A rapid review was conducted in five databases PubMed, EMBASE, Web of Science, Scopus and LILACS to synthesize recent evidence on the use of AI for preventing maternal mortality due to hypertension and postpartum hemorrhage. Studies published in the last five years that included racial or ethnic data were selected and analyzed narratively. Results: Ten studies met the inclusion criteria, showing high predictive accuracy of AI models (AUROC often >0.95) for severe maternal outcomes. However, few models incorporated racial variables or underwent external validation in racially diverse or low-resource populations. Evidence suggests that unrepresentative datasets may perpetuate or exacerbate existing health inequities. Conclusions: AI demonstrates strong technical performance in predicting maternal complications but limited equity in application. Broader racial representation, external validation, and ethical governance are essential for ensuring that AI-based tools reduce rather than reinforce racial disparities in maternal mortality.

Abstract: Soto Zen Buddhist precepts, contemplative medicine, and nursing are used to examine ethical and spiritual ramifications of being silent in the face of environmental destruction and nuclear hazards. It explores how spiritual integrity can guide personal, professional, and planetary development using a personal narrative based on Soto Zen practice and training in contemplative medicine, as well as a scoping review on spirituality in the Anthropocene. The ongoing threat of nuclear disaster can lead to an instantaneous and irreversible detachment from life, even as climate change takes center stage in international debate. By integrating contemplative frameworks with nursing and interfaith perspectives, the paper positions spirituality as a critical dimension of sustainability and calls for a cultural and spiritual shift toward connection, humility, and reverence as a foundation for planetary health.

Abstract: Objectives: Role clarity is a persistent challenge among Patient Care Technicians (PCTs), contributing to inconsistent task performance and safety risks. In Saudi Arabia, little is known about PCTs’ understanding of their responsibilities. This study assessed baseline knowledge and evaluated the impact of a targeted educational program aimed at improving clarity in roles, safety practices, and communication. Methods: A quasi-experimental pre–post design was used in September 2025 with 35 participants from the Hail Health Cluster. The one-day intervention included lectures, discussions, role-play, and case scenarios. A validated survey assessed four domains: role clarity, core clinical tasks and safety, communication and ethics, and objective knowledge. Paired t-tests were performed using SPSS v29, with effect sizes reported via Cohen’s d. Results: Baseline scores were lowest in objective knowledge (41.4%) and role clarity (62.8%). Post-training, total composite scores improved significantly (+10.88%, p < .001), with the greatest gain in objective knowledge (+19.8%, p < .001). Role clarity showed only a modest, non-significant increase (+3.98%, p = .088). No demographic differences were found. Conclusion: Training enhanced PCT knowledge, but improving role clarity may require longer-term, system-level strategies.

Abstract: Background: The COVID-19 pandemic exacerbated pre-existing inequities in maternity care, particularly among culturally diverse and migrant women. Although data were col-lected during the early pandemic phase, revisiting these experiences offers valuable in-sights for strengthening equity, cultural safety, and system preparedness in maternal healthcare. Methods: A qualitative phenomenological–hermeneutic study was conducted in a tertiary maternity hospital in Spain. Semi-structured interviews were carried out with six women from diverse cultural backgrounds. Data were analysed inductively through thematic analysis, followed by a secondary interpretive review in 2024 to identify endur-ing implications for culturally safe, equitable, and crisis-resilient maternity care. Results: Four main themes emerged: (1) heightened fear and uncertainty surrounding hospital care; (2) emotional distress linked to restrictions on companionship and support; (3) dis-ruption of culturally embedded postpartum practices, resulting in isolation; and (4) health literacy barriers and dependence on informal information sources. Despite these chal-lenges, participants demonstrated notable adaptability and resilience. Conclusions: COVID-19 amplified structural inequities in maternity care for culturally diverse mothers. The findings highlight the need to reinforce cultural safety, health literacy support, lan-guage mediation, family-centred care, and emotional wellbeing. These lessons offer ac-tionable guidance for strengthening resilient, equitable maternal health systems and im-proving preparedness for future public health emergencies.

Abstract:

Background: Digital transformation in healthcare has progressed rapidly in hospitals and primary care, while long-term care facilities have often been left behind. The CareConnect project, funded under the German Model Program for Telecare (§ 125a SGB XI), aimed to implement and evaluate a comprehensive telecare system in two nursing homes in Germany, to improve collaboration across sectors, enhance communication between professionals, and strengthen nurses’ digital competencies. Objective: This implementation study examined the feasibility, acceptability, and early adoption of a multiprofessional telecare system in nursing homes, identifying key facilitators, barriers, and perceived effects on interprofessional collaboration and care delivery. Methods: A participatory implementation design was employed over 15 months (June 2024–August 2025), involving a university hospital, two nursing homes (NHs), and four medical practices in an urban region. The intervention consisted of teleconsultations and interdisciplinary case discussions utilizing a certified video platform, combined with diagnostic devices (e.g., otoscopes, dermatoscopes, ECGs). Implementation data included quantitative usage statistics, researcher observations, and user feedback collected during the rollout phase. Data were analyzed descriptively to assess usage patterns, case characteristics, and implementation experiences. Results: A total of 152 documented telecare contacts were conducted with 69 participating residents. Most interactions occurred with general practitioners (48.7%) and dermatologists (23%). Across all contacts, in 79% of cases, there was no need for an in-person visit or transportation. Physicians rated most cases as suitable for digital management, as indicated by a mean of 4.09 (SD = 1.00) on a 5-point Likert scale. Nurses reported improved communication, time savings, and enhanced technical and diagnostic skills. Key challenges included delayed technical integration, interoperability issues, and varying interpretations of data protection requirements across facilities. Conclusions: The CareConnect pilot demonstrates that telecare can effectively improve access to specialized care and strengthen interprofessional collaboration in nursing homes. A participatory, user-centered approach proved crucial for acceptance and sustainability. Future scale-up requires stable technical infrastructures, clear reimbursement pathways, and harmonized legal frameworks.

Abstract: Background: Compassion is a cornerstone of woman-centred maternity care and a critical determinant of women’s experiences of childbirth. When dignity, empathy, and effective communication are upheld, women perceive childbirth as safe, empowering, and affirming. However, evidence from many settings highlights the persistence of disrespect, neglect, and abuse during facility-based intrapartum care, undermining trust in health services and contributing to poor maternal outcomes. Objectives: This scoping review explored and synthesized evidence on women’s experiences and per-ceptions of care, with a focus on how compassionis are experienced and enacted in healthcare settings. Methods: A systematic search was conducted across EBSCOhost databases, ScienceDirect, CINAHL, PubMed, Web of Science, Medline, and PsycINFO. Fifteen studies met the inclusion criteria. Data was charted and thematically analyzed to identify the role of compassion and related interpersonal factors in shaping wom-en’s intrapartum experiences. Results: The review of fifteen studies identified two main themes and 12 sub-themes related to childbirth experiences. Compassionate care, characterized by respect, empathy, effective communication, and support for autono-my, led to positive childbirth outcomes and encouraged future use of health services. Conversely, care encounters lacking relational elements, including neglect, mistreat-ment, discrimination, and unconsented care, resulted in feelings of humiliation and disempowerment, discouraging women from seeking facility-based care in future. Conclusion: Compassion during intrapartum care is both a fundamental human right and an essential component of quality maternal health services. Addressing persistent mistreatment requires systemic reform, provider training in compassionate, rights-based care, stronger accountability, and the active inclusion of women’s voices in shaping maternity services.

Abstract: Background: Multiple sclerosis (MS) is a chronic autoimmune disease of the central nervous system that causes progressive disability and psychosocial burden. Understanding how MS affects patients’ quality of life (QoL) is essential for developing patient-centered rehabilitation and psychosocial support interventions. Methods: A cross-sectional study was conducted among adults diagnosed with MS residing in Western Greece. Data were collected using the Multiple Sclerosis Quality of Life-54 (MSQOL-54) questionnaire. Demographic and clinical variables (age, gender, disease duration, and functional status) were analyzed using descriptive and inferential statistics. Pearson correlation and multiple regression analyses were performed to identify factors associated with QoL domains. Additionally, a systematic literature review following PRISMA guidelines was integrated to contextualize findings within the broader evidence base on MS-related QoL. Results: The study included 128 participants (72% female, mean age 39.8 ± 9.4 years). Overall QoL scores indicated moderate impairment (mean composite physical score = 53.6; mental health = 57.4). Fatigue, pain, and depressive symptoms were strongly correlated with lower QoL (p < 0.001). Longer disease duration and higher disability (EDSS ≥ 4) predicted poorer physical functioning. Conversely, higher perceived social and family support predicted better psychological adaptation and higher mental health scores (β = 0.42, p < 0.01). The PRISMA review synthesized 45 studies, confirming disability, fatigue, and depression as universal risk factors, while social support and resilience-building interventions emerged as protective elements. Conclusion: MS substantially impacts both physical and psychosocial dimensions of life. The findings emphasize the importance of integrated care models that combine medical treatment with psychosocial and rehabilitation programs focusing on resilience, coping, and social support. Early interventions may mitigate QoL deterioration and promote holistic well-being. Regional disparities in Western Greece highlight the need for tailored, accessible services.

Abstract: Background/Objectives: Assisted suicide and suicide prevention remain subjects of intense societal, political, and professional-ethical debate in Germany. Nurses working in residential and home-based long-term care (LTC) play a pivotal role in responding to requests for assisted suicide and in supporting suicide prevention. While international research has explored diverse ethical perspectives and challenges related to these issues, little is known about how LTC nurses in Germany experience and navigate them. This study examines German LTC nurses’ ethical perspectives on assisted suicide and suicide prevention and explores the associated ethical challenges. Methods: A qualitative design employing both in-person and online focus groups was used. Data were analyzed following Mayring’s qualitative content analysis. Results: Twelve focus groups with a total of 96 nurses working in residential and home-based LTC were conducted between February and September 2025. Findings show that nurses perceive assisted suicide and suicide prevention as ethically complex and emotionally demanding. Three overarching themes emerged: (1) Intuitive and Emotional Reactions, (2) Ethical Perception and Ethical Reflection, and (3) Ethical Challenges. Conclusions: LTC nurses expressed varying ethical perspectives on and attitudes towards assisted suicide and suicide prevention. The ethical challenges identified may contribute to the development of moral distress. To help nurses navigate these ethically demanding situations, strategies at multiple levels are required. These include continuous ethics education, an open ethical culture, role definitions and clear professional guidance, alongside societal support for equitable access to general healthcare and suicide prevention services.

Abstract: Aim: To examine the professional role development of new graduate nurses (NGNs) across three transition stages within a major Australian health service. Background: The shift from student to registered nurse is a critical period marked by emotional strain, role ambiguity, and transition shock. Structured support programs have emerged to ease this transition, yet few are evaluated through longitudinal, theory-informed approaches using validated tools. Design: A longitudinal quantitative study guided by Duchscher’s Stages of Transition Theory and the Transition Shock Model. Methods: A customised 75-item questionnaire, adapted from the Professional Role Transition Risk Assessment Instrument and Professional and Graduate Capability Framework, was distributed across three transition points (March 2020 to March 2021). The survey assessed four domains: Responsibilities, Role Orientation, Relationships, and Knowledge and Confidence. Descriptive statistics, Principal Component Analysis, Chi-square tests, and multinomial logistic regression were used to analyse patterns, trends, and predictors of successful transition. Results: A clear developmental trajectory emerged. Early-stage participants experienced stress, low self-efficacy, and role confusion. By Stage 3, most demonstrated increased clinical confidence, autonomy, and integration into professional healthcare teams. A coordinator-to-graduate ratio of 1:12 facilitated personalised mentorship and supportive practice environments. Statistically significant improvements were observed in critical thinking, leadership perception, emotional resilience, and team communication. Conclusions: This study provides robust empirical support for theoretically grounded and policy-aligned Graduate Nurse Transition Programs. Targeted interventions tailored to each transition phase—such as early mentorship, mid-stage stress support, and end-stage leadership development—can enhance confidence, improve role clarity, and promote long-term workforce capability and sustainability.

Abstract: Background: Malnutrition is highly prevalent among older adults with cognitive impairment, contributing to frailty, reduced immunity, and poorer health outcomes. The majority of people with dementia require eating assistance during mealtime to maintain adequate nutritional intake (Tang, et al., 2025). While the role of professional caregivers in nursing homes is well documented, the contribution of family caregivers in hospital settings remains underexplored. Aim: To explore the distinct mealtime assistance practices provided by family caregivers in hospitals and professional caregivers in nursing homes for cognitively impaired older adults. Methods: A cross-sectional observational study was conducted in New South Wales, Australia, including 82 older adults (≥65 years) with cognitive impairment: 31 hospital patients assisted by family caregivers and 51 nursing home residents assisted by professional caregivers. Nutritional status was assessed using the Mini Nutritional Assessment–Short Form (MNA-SF), feeding difficulties with the Feeding Difficulty Index (FDI), and caregiver practices with observational checklists of encouragement and technical skills. Independent t-tests were performed, with significance set at p< 0.05. Results: Nursing home residents consumed a greater proportion of meals (76% vs. 56%) and displayed fewer feeding difficulties than hospital patients. Professional caregivers demonstrated broader technical skills, such as mouth opening (27.5% vs. 0%, p< 0.001), lip-opening techniques (31.4% vs. 0%, p< 0.001) and choking management (78.4% vs. 25.8%, p=0.004). In contrast, family caregivers provided stronger relational support, including sitting facing the patient (90.3% vs. 31.4%, p< 0.001), using verbal cueing (100% vs. 68.6%, p=0.001), and engaging in conversation (100% vs. 64.7%, p=0.003). Consequently, the mean nutritional status (MNA-SF score) was significantly poorer in the hospital group (6.03 vs. 10.24, p< 0.001). Conclusion: Family and professional caregivers demonstrate complementary strengths in mealtime care. Integrating the relational engagement of family caregivers with the technical expertise of staff through targeted training and policy initiatives may improve nutritional outcomes and reduce malnutrition in cognitively impaired older adults across hospital and nursing home settings.

Abstract:

Background/Objectives: Pressure injuries and falls are frequent hospital adverse events. Identifying high-risk periods during hospitalization is essential for guiding effective prevention. In this study, we aimed to estimate the time from hospital admission to the occurrence of pressure injuries and/or falls and analyze its relationship with the nursing assessment at admission. Methods: A longitudinal observational study was conducted with a systematic sample of 314 adult patients admitted between January and May 2024. Survival analysis was performed to describe the temporal distribution of adverse events and compare their occurrence across nursing assessment variables using the log-rank test. Poisson Generalized Linear Models were applied to explore associated factors. Results: Fifteen pressure injuries and four falls were recorded. Overall, 63% of these adverse events occurred within the first five days of hospitalization. Patients with lower functional capacity (log-rank p<0.001) and high-pressure injury risk (log-rank p<0.001) according to the VALENF Instrument were more likely to acquire new pressure injuries. Similarly, fall risk scores (log-rank p=0.037) obtained with the same instrument were associated with falls. Patients classified as high risk for pressure injuries showed a nine-fold higher likelihood of developing new injuries (Wald χ², p < 0.001), while urgent admission further increased this risk more than six-fold (Wald χ², p = 0.015). Conclusions: This exploratory study highlights the value of early nursing assessment using the VALENF Instrument in identifying high-risk patients and planning timely, individualized preventive care during hospitalization.

Abstract: Background/Objectives: In Japan, the rapid aging of the population has increased the need for strategies to extend healthy life expectancy and prevent care dependency. Social isolation has been identified as a major risk factor for adverse physical and psychological outcomes, but its interaction with psychological resilience factors remains unclear. This study aimed to examine the association between social isolation and the risk of care dependency among community-dwelling older adults, and to investigate whether the sense of coherence (SOC) moderates this relationship. Methods: A cross-sectional survey was conducted in City A, Kagawa Prefecture, in-volving 519 residents aged 65 years or older. Social isolation was assessed using the Japanese version of the Lubben Social Network Scale-6 (LSNS-6), and SOC was measured with a validated three-item scale from the University of Tokyo. The risk of care dependency was evaluated using a 15-item checklist developed by the Tokyo Metropolitan Institute of Gerontology. Nutritional status was measured using the Mini Nutritional Assessment–Short Form. Multiple imputation (m = 50) handled missing data. Standardized linear regression analyses estimated main and interaction effects, followed by robustness checks using robust, gamma, and bootstrap analyses. Results: Lower levels of social connectedness were significantly associated with a higher risk of care dependency. SOC significantly moderated this relationship (β = 0.100, p = .004), indicating that the negative impact of social isolation was more pronounced among individuals with lower SOC. Conclusions: SOC may function as a psychological buffer mitigating the adverse im-pact of social isolation. Enhancing internal coping resources could be a useful strategy for preventive care programs among older adults. This study was not registered.

Abstract: Background: Clinical simulation is pivotal for developing nursing competence, yet the predictors of perceived comprehensiveness among students remain underdescribed in multidisciplinary contexts. Methods: Cross-sectional study of 926 students from eight health programs at a Colombian higher-education institution. A validated questionnaire (benefits, contributions, and academic complement) was used, and the association with perceived comprehensiveness was modelled using multivariable regression. Results: 90.9% rated simulation as comprehensive. The “contributions” domain—especially reinforcement of theoretical knowledge and clinical reasoning—was the strongest predictor (adjusted effect estimate ≈ 4.59, 95% CI 2.41–8.72). Higher agreement was also observed among women, rural residents, single students, and those in advanced semesters. Comparatively lower-scoring items pointed to realism in decision-making and protected time. Conclusions: From a nursing perspective, perceived comprehensiveness depends primarily on the educational value that strengthens clinical reasoning and theory-to-practice integration—core components of competence frameworks (e.g., QSEN, Jeffries). Enhancing fidelity, decision-making scenarios, and protected time may accelerate competence attainment and promote equity among students with limited clinical exposure.

Abstract: Aim: This qualitative study sought to explore the fundamental characteristics of the disease experiences among children living with chronic kidney disease. Methods: A phenomenological research approach was utilized. Results: Through comprehensive interviews with 13 adolescents diagnosed with chronic kidney disease, seven theme clusters were identified, reflecting diverse dimensions of their disease experiences: “appearance and worsening of kidney disease symptoms,” “restrictions in daily living,” “unstable self-control,” “changes in relationships with friends,” “sensitivity about a decrease in achievements due to disease,” “efforts to maintain a normal daily life,” and “psychological, physical, and social strengthening.” The core nature of the disease experience for children with chronic kidney disease was characterized as “overcoming experiences of limitations due to chronic kidney disease and exhibiting resilient growth.” Conclusions: The findings provide important perspectives for comprehensively understanding the disease-related experiences of children with chronic kidney disease. The study highlights the importance of interdisciplinary efforts, objective assessment tools, and robust conceptual frameworks to advance interventions and supportive strategies for these patients.

Abstract: Background: Heat exposure is rapidly becoming one of the most pressing health issues of the 21st century. Much work to date has focused on the impact of high heat conditions on outdoor workers but not focused on indoor workers who may be exposed to high heat conditions, such as restaurant workers. Restaurant workers are frequently exposed to high heat conditions at work due to increasing environmental temperatures and occupational factors. Of particular concern to heat exposed workers are the impact of occupational heat exposure on the kidneys, which has shown to cause acute kidney injury simply from working in the heat. Purpose: The purpose of this scoping review is to identify what studies have been completed investigating the impact of heat exposure on kidney functioning in restaurant workers. Methods: We followed Arksey and O’Malley’s 5-step framework for conducting scoping reviews. Searches were conducted in PubMed, CINAHL, Embase, and Web of Science. Results: Of the 287 studies identified, 246 were screened at the title and abstract level and four full texts were screened. Ultimately, 2 journal articles and 1 conference proceeding were included in this review. All three studies were conducted internationally, with two collecting data primarily in the winter or spring. None of the studies utilized similar protocols for measuring heat strain nor kidney function. Application to Practice: Findings underscore the urgent need for occupational health professionals to implement standardized heat monitoring and hydration protocols in restaurant settings and advocate for policies extending indoor heat protections to food service workers.

Abstract: Objective: To analyze the advances and challenges of the Nursing Policy Dialogue in Uruguay initiated in 2021, based on the experiences of nurses who actively participated in its process and follow-up of the agreements. Methods: Qualitative exploratory study with a hermeneutic-dialectic approach. In-depth interviews were conducted with 12 nurses se-lected through theoretical-purposive sampling. The interviews were transcribed and ana-lyzed using content analysis. Results: Five main categories were constructed: partial achievements under critical scrutiny; need to design policies; challenging collective con-struction; local networks of professional action; representation and emerging leadership. These categories reflect both the advances achieved and the challenges, obstacles, and opportunities that persist in the development of the national Nursing plan. Conclusions: This study identified advances and challenges, including partial achievements, the need for specific public policies, collective construction, and the emergence of territorial leader-ship. The nursing policy dialogue represents the beginning of a path that requires conti-nuity, political will, and institutional commitment to achieve concrete and sustainable policies.

Abstract: Background: Healthcare professionals working with chronic patients for a long time are at risk of compassion fatigue and burnout (BO). Our study aims to compare the levels of BO and the workplace-influencing factors of health care employees working in a dialysis center or satellite unit. Methods: We conducted the present study in two types of dialysis units: a centre and a satellite. The patient’s physical status and comorbidities were quantified by Karnofsky Performance Scale (KPS) and Charlson Comorbidity Index (CCI) and compared between these units. The research was conducted with 39 healthcare employees (30 nurses, 4 doctors and 5 other medical staff). Participants were enrolled using a convenience sampling technique at the dialysis outpatient services in Pécs, Hungary. Personal information forms, the Maslach Burnout Inventory (MBI), the Mini Oldenburg Burnout Inventory (MOLBI), the Dysfunctional Attitude Scale (DAS-SFI), and Beck’s Depression Inventory (BDI) questionnaires were used. Results: There was a significant difference in the patients’ KPS (67.9 vs. 85.7, p < 0.001) and CCI (6.62 vs. 5.55, p = 0.003) treated in center and in satellite unit. Our MBI analysis comparing the dialysis workplaces (center vs. satellite unit) revealed that health care employees report significantly higher and more severe BO working in the dialysis center compared to the satellite unit. Multiple stepwise linear regression analyses showed a strong prediction of the center workplace (p = 0.022) for BO syndrome. There was a positive correlation between MOLBI of the employees and CCI of the patients (p = 0.028, r = 0.426). Conclusions: This study confirmed that the condition of the treated patients plays an important role in the development of the BO syndrome among dialysis health care professionals. There was more severe BO employees working in the center compared to those working in the satellite unit. Our results indicate that measures to prevent BO should be implemented in dialysis units.

Abstract: Background/Objectives: Healthcare-associated infections (HAIs) require specific skills in nursing education, yet their curricular integration often remains fragmented, limiting the consolidation of knowledge and safe clinical practice. This study aimed to explore the perceptions of nursing students from Brazil and Peru regarding the use of clinical simulation as a strategy to develop skills in HAIs prevention and control. Methods: A qualitative approach was employed, involving 12 focus groups (n = 247 students) across four universities. The discussions were conducted following simulation activities based on standardized scenarios structured into four phases: pre-reading, briefing, execution, and debriefing. Data were collected using a semi-structured interview guide and analyzed thematically until thematic sufficiency was achieved. The study adhered to COREQ guidelines. Results: Three main themes emerged: i) clinical simulation as a student-centered teaching-learning strategy, where pre-reading and briefing materials enhanced students’ confidence and clarity in performing tasks, with checklists suggested to avoid omissions; ii) simulation as a facilitator of autonomy and safety in HAI prevention, offering a protected environment for making mistakes and learning, with formative feedback during debriefing increasing risk awareness, although debriefing time was noted as an area for improvement; and iii) meaningful learning and integration with traditional education, as students reported increased engagement, better knowledge retention, and greater perceived transfer of skills to real clinical settings. Conclusions: Clinical simulation demonstrated strong potential to support the development of HAI prevention skills in undergraduate nursing students. Longitudinal implementation with standardized scenarios and further evaluation of educational effectiveness and debriefing strategies is recommended.

Abstract: Introduction: Anxiety is an emotional response characterized by excessive tension, worry, and physiological changes that interfere with academic performance and well-being. In university students, especially those in the health sciences, its prevalence is high due to factors such as academic load, pressure for performance, and job uncertainty. Methods: A cross-sectional descriptive study was conducted using non-probabilistic sampling in 109 nursing students. Results: The STAI-State questionnaire was used to measure anxiety levels, which were differentiated according to gender. The mean anxiety level was 23.75 points (standard deviation = 8.54), with medium-high levels predominating in both sexes, with a higher prevalence in women (31.9%). Most students had low-to-moderate levels of anxiety, although a significant percentage had high levels of anxiety. Conclusion: The high prevalence of anxiety among nursing students reinforces the need for clinical practice preventive and management programs to improve well-being, performance, and professional preparation.

Abstract: Background: Relapsing-remitting multiple sclerosis is a chronic neurological disease that affects the central nervous system, with a significant impact on health-related quality of life. Main: To determine the sociodemographic, clinical, and quality of life characteristics, establish relationships, and identify predictive factors for quality of life. Methods: An observational, analytical, and prospective study was conducted with 35 participants diagnosed with relapsing-remitting multiple sclerosis at the Lucus Augusti University Hospital between January 2023 and March 2025. The MSQOL-54 questionnaire was used to assess quality of life and its dimensions at diagnosis, three months, and six months. Data were analyzed using non-parametric tests with SPSS v24 software. Results: Perceived quality of life demonstrated overall stability (mean score of 62 points), although dimensions such as emotional limitations and social functioning worsened. Factors such as family history, autoimmune diseases, and lifestyle habits were significantly associated with quality of life. Initial quality of life was found to predict its future trajectory. Conclusion: Quality of life among individuals with relapsing-remitting multiple sclerosis remains generally stable, though certain dimensions tend to deteriorate. Early and multidimensional interventions could mitigate the cumulative impact of the disease and improve perceived quality of life, particularly in emotional and social domains.