ARTICLE
|
doi:10.20944/preprints202308.0290.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
RNA-binding protein; human antigen R (HuR); high-throughput virtual screening; small molecule inhibitors; RNA pulldown assay
Online: 3 August 2023 (10:11:15 CEST)
ARTICLE
|
doi:10.20944/preprints202301.0035.v1
Subject:
Medicine And Pharmacology,
Psychiatry And Mental Health
Keywords:
BRFSS; Bereavement; Grief; Mental Health; Physical Health; Population Surveillance; Social de-terminants of health; Multiple Imputation; Screening
Online: 4 January 2023 (01:54:29 CET)
REVIEW
|
doi:10.20944/preprints202209.0201.v1
Subject:
Chemistry And Materials Science,
Medicinal Chemistry
Keywords:
ligand-based pharmacophores; structure-based pharmacophores; virtual screening; drug design; machine learning; molecular dynamics; de novo design
Online: 14 September 2022 (09:10:58 CEST)
ARTICLE
|
doi:10.20944/preprints202104.0475.v1
Subject:
Medicine And Pharmacology,
Immunology And Allergy
Keywords:
drug repurposing; virtual screening; multiscale; multitargeting; polypharmacology; computational biology; drug repositioning; structural bioinformatics; molecular docking; proteomic signature
Online: 19 April 2021 (12:22:05 CEST)
ARTICLE
|
doi:10.20944/preprints202312.1430.v1
Subject:
Medicine And Pharmacology,
Neuroscience And Neurology
Keywords:
Alzheimer’s disease 1; plasma amyloid 2; SIMOA 3; plasma Aβ42/Aβ40 ratio 4; amyloid prediction 5; biomarkers 6; Alzheimer’s disease screening 7
Online: 19 December 2023 (10:19:53 CET)
ARTICLE
|
doi:10.20944/preprints202306.1818.v1
Subject:
Biology And Life Sciences,
Biology And Biotechnology
Keywords:
Alternative Splicing; two-colour (GFP/RFP) Fluorescent Reporter; MAPT; Exon-Skipping; FTDP-17; High Content Screening; siRNA; Nucleic Acids Therapeutics; Drug discovery
Online: 26 June 2023 (13:55:26 CEST)
ARTICLE
|
doi:10.20944/preprints202311.0727.v1
Subject:
Medicine And Pharmacology,
Pediatrics, Perinatology And Child Health
Keywords:
newborn screening; lysosomal storage disease; Pompe disease; Mucopolysaccharidosis type I; Gaucher disease; Fabry disease; second tier test; tandem mass spectrometry; glycosaminoglycans; lysosphingosine.
Online: 10 November 2023 (16:19:05 CET)
ARTICLE
|
doi:10.20944/preprints202006.0091.v1
Subject:
Computer Science And Mathematics,
Computer Science
Keywords:
Breast Cancer Screening; Digital Image Elasto Tomography (DIET); Image Noise Removal, Image Enhancement; Multiple Frame Noise Removal (MFNR)
Online: 7 June 2020 (14:53:34 CEST)
ARTICLE
|
doi:10.20944/preprints202105.0073.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
workplace testing; economic analysis; COVID-19; asymptomatic screening; mass testing; employee population health; return to work practices; SARS-CoV-2; surveillance; workplace mitigation
Online: 6 May 2021 (11:34:57 CEST)
ARTICLE
|
doi:10.20944/preprints202103.0403.v1
Subject:
Biology And Life Sciences,
Immunology And Microbiology
Keywords:
non-canonical branched chain amino acids; scale-down; strain screening; mixed-acid fermentation; pyruvate pulse; norvaline; norleucine; fed-batch cultivation; bioreactor; Enpresso; Enbase
Online: 16 March 2021 (09:11:34 CET)
ARTICLE
|
doi:10.20944/preprints202106.0020.v1
Subject:
Biology And Life Sciences,
Virology
Keywords:
Vesicular Stomatitis; Herpes Simplex; Yellow Fever; Animal Viruses; Plaque Assay; Real-time; Live Cell Imaging, Automated Image Analysis; DNA Fluorescent Dyes, Antiviral Screening
Online: 1 June 2021 (10:40:37 CEST)
ARTICLE
|
doi:10.20944/preprints202311.1911.v1
Subject:
Medicine And Pharmacology,
Pediatrics, Perinatology And Child Health
Keywords:
infrared thermal imaging; toddler’s fracture; bone fracture screening; infrared thermal image processing and analysis; artificial intelligence; emergency medicine; orthopaedics
Online: 29 November 2023 (16:40:58 CET)
ARTICLE
|
doi:10.20944/preprints202210.0100.v1
Subject:
Medicine And Pharmacology,
Cardiac And Cardiovascular Systems
Keywords:
screening after pulmonary embolism; chronic thromboembolic pulmonary disease; chronic thromboembolic pulmonary hypertension; diagnostic work-up of post-pulmonary syndrome
Online: 9 October 2022 (02:09:20 CEST)
REVIEW
|
doi:10.20944/preprints202308.0434.v1
Subject:
Medicine And Pharmacology,
Medicine And Pharmacology
Keywords:
In silico studies; drug discovery; SARS-CoV-2; molecular docking; virtual screening; molecular dynamics simulations; drug candidates; antiviral activity; receptor-ligand complex; drug design
Online: 4 August 2023 (11:11:21 CEST)
REVIEW
Subject:
Biology And Life Sciences,
Virology
Keywords:
Chikungunya virus; alphavirus; antiviral therapy; direct-acting antivirals; host-directed antivirals; in silico screening; in vivo validation; antiviral drug development
Online: 10 June 2021 (09:15:45 CEST)
REVIEW
|
doi:10.20944/preprints202009.0256.v1
Subject:
Chemistry And Materials Science,
Physical Chemistry
Keywords:
attractive and repulsive forces; Debye’s screening length (1/k); Poisson-Boltzmann (PB) equation; food colloids; coagulation; stabilizers; lipids; polymers; electrolytes
Online: 11 September 2020 (10:05:50 CEST)
ARTICLE
|
doi:10.20944/preprints201911.0023.v1
Subject:
Biology And Life Sciences,
Biology And Biotechnology
Keywords:
monoclonal antibodies; Mabs; fusion; false positives; hapten immunoassays; competitive immunoassays; ELISA; antibody validation; antibody quality; microarray; hybridoma technology; linker recognition; high-throughput screening; HTS; heterology concept
Online: 3 November 2019 (17:00:59 CET)
ARTICLE
|
doi:10.20944/preprints202301.0340.v1
Subject:
Biology And Life Sciences,
Food Science And Technology
Keywords:
alternative food; resilient food; distributed production; edible plants; existential risk; food security; global catastrophic risk; leaf concentrate; leaf protein; non-target screening; resilience; sustainable food systems; toxins
Online: 19 January 2023 (01:57:51 CET)
COMMUNICATION
|
doi:10.20944/preprints202404.1556.v1
Subject:
Immunology And Allergy,
Medicine And Pharmacology
Keywords:
Methylated Cyclodextrin; Cyclodextrin; KLEPTOSE® CRYSMEB; anti-inflammatory; immunity; HUVEC; BCS; T cell; Diversity PLUS® Panel; chemokines; polyunsaturated fatty acid; lipoxins; resolvins; maresins; protectins; Peripheral Blood Mononuclear Cell, screening; cytokine
Online: 24 April 2024 (07:09:16 CEST)
ARTICLE
|
doi:10.20944/preprints202005.0001.v1
Subject:
Biology And Life Sciences,
Cell And Developmental Biology
Keywords:
CRISPR-Cas9; high-content screening (HCS); fluorescent-activated cell sorting (FACS); Parkinson's disease (PD); patient-derived iPS; single-cell clones; isogenic cell lines; SNCA; alpha-synuclein; A30P
Online: 2 May 2020 (11:20:20 CEST)
ARTICLE
|
doi:10.20944/preprints202310.1811.v1
Subject:
Medicine And Pharmacology,
Obstetrics And Gynaecology
Keywords:
Cervical cancer; HPV screening; Prevention strategies; Human Papillomavirus; HIV interaction; "Test and Treat" approach; Number Needed to Treat; Positive Predictive Value; Negative Predictive Value; Risk management; Global health challenges
Online: 27 October 2023 (13:21:23 CEST)