CASE REPORT
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doi:10.20944/preprints202405.2167.v1
Subject:
Medicine And Pharmacology,
Pathology And Pathobiology
Keywords:
chronic EBV infection; T cell lymphoproliferative disorder; mutational profile
Online: 3 June 2024 (07:58:45 CEST)
ARTICLE
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doi:10.20944/preprints201811.0280.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
HSP47; missense mutation; mutational hotspot; variant analysis; cancer database; chaperone
Online: 12 November 2018 (10:23:29 CET)
ARTICLE
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doi:10.20944/preprints202003.0181.v1
Subject:
Biology And Life Sciences,
Plant Sciences
Keywords:
Ashwagandha; Chloroplast Genome; InDels; Medicinal plants; Mutational hotspots; Phylogenomics; Solanaceae; Substitutions; Withania
Online: 11 March 2020 (10:21:56 CET)
REVIEW
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doi:10.20944/preprints202305.1258.v1
Subject:
Biology And Life Sciences,
Life Sciences
Keywords:
acute myeloid leukemia; genetic classification; mutational profiling; transcriptome analysis; prognostic stratification; clonal evolution
Online: 17 May 2023 (14:36:39 CEST)
ARTICLE
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doi:10.20944/preprints202210.0404.v1
Subject:
Biology And Life Sciences,
Virology
Keywords:
COVID-19; SARS-CoV-2 Omicron; tMRCA; evolutionary rate; mutational profiling; selection pressure
Online: 26 October 2022 (08:15:25 CEST)
REVIEW
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doi:10.20944/preprints202304.0999.v1
Subject:
Public Health And Healthcare,
Public Health And Health Services
Keywords:
Barrett’s esophagus; inflammatory signaling pathways; intestinal metaplasia; mutational load; p53; dysplasia; carcinogenesis; esophageal adenocarcinoma
Online: 26 April 2023 (15:01:48 CEST)
SHORT NOTE
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doi:10.20944/preprints202006.0250.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
Nucleotide composition; mutational change; GC to AT; COVID-19; SARS-CoV-2; Vaccine design
Online: 21 June 2020 (10:16:01 CEST)
REVIEW
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doi:10.20944/preprints202305.1239.v1
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
Hodgkin lymphoma; non-Hodgkin lymphoma; PD1 / PD-L1 checkpoint inhibitors; tumor mutational burden; predictive biomarkers
Online: 17 May 2023 (10:52:16 CEST)
REVIEW
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doi:10.20944/preprints202407.2623.v1
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
Tumor Mutational Burden (TMB); Immune Checkpoint Inhibitors (ICIs); Biomarkers; Cancer Immunotherapy; Cancer Treatment Outcomes; Personalized Medicine
Online: 2 August 2024 (11:50:44 CEST)
REVIEW
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
continuous evolution; protein design; protein engineering; phage; bacterial one-hybrid; plaque assay; mutational analysis; DNA sequencing
Online: 5 November 2019 (02:19:01 CET)
ARTICLE
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doi:10.20944/preprints202309.0511.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
NtcA; EngA; Synechococcus elongatus; nitrogen regulation network; light and dark conditions; PipX toxicity; energy sensing; mutational analysis
Online: 7 September 2023 (11:23:14 CEST)
REVIEW
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doi:10.20944/preprints202410.0644.v1
Subject:
Medicine And Pharmacology,
Urology And Nephrology
Keywords:
malignant melanoma; urological cancers; risk factors; shared genetic mutations; lifestyle changes; personalized treatment; tumor mutational burden; angiogenesis inhibitors; checkpoint inhibitors
Online: 9 October 2024 (10:58:57 CEST)
ARTICLE
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doi:10.20944/preprints202107.0295.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
SARS-CoV-2 spike protein; ACE2 host receptor; nanobodies; molecular dynamics; mutational sensitivity; binding free energy; allosteric interactions; signal transmission
Online: 13 July 2021 (11:18:02 CEST)
HYPOTHESIS
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doi:10.20944/preprints202010.0199.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
CRISPR interference; error-prone polymerase chain reaction; ribosomal proteins; ribosome; viability assay; Bacillus subtilis; Escherichia coli; sequence space; conformational space; mutational map
Online: 9 October 2020 (12:24:14 CEST)
ARTICLE
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doi:10.20944/preprints202410.1043.v1
Subject:
Biology And Life Sciences,
Aging
Keywords:
aging; antagonistic pleiotropy (AP); Blueprint synthesis; dysactivity; ecology; extrinsic mortality; evolution; life history theory; mutational accumulation (MP); nested doll principle; network constraint; patho-pathway
Online: 14 October 2024 (15:24:13 CEST)
REVIEW
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
Neuroendocrine Neoplasms; NOTCH; cancer driven genes; mutational mechanism; germline mutations.; small cell lung carcinoma; pancreatic NET; small bowel NET; medullary thyroid carcinoma; malignant castration-resistant prostatic cells
Online: 23 July 2019 (10:34:50 CEST)
REVIEW
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doi:10.20944/preprints202104.0484.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
RNA world theory; Viral RNA; Genome stability; Viral evolution; Mutational signatures; RNA dependent RNA polymerase, RdRp; RNA recombination; RNA damage; Hypermutation; APOBEC; ADAR; RNA editing; SARS-CoV-2; rubella virus
Online: 19 April 2021 (13:22:01 CEST)
REVIEW
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doi:10.20944/preprints202305.1344.v1
Subject:
Medicine And Pharmacology,
Pathology And Pathobiology
Keywords:
mediastinal gray-zone lymphoma; classical Hodgkin lymphoma; primary mediastinal B-cell lymphoma; diffuse large B-cell lymphoma; NOS; EBV-positive diffuse large B-cell lymphoma; NOS; morphology; phenotype; gene expression profile; mutational landscape
Online: 18 May 2023 (12:25:07 CEST)
ARTICLE
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doi:10.20944/preprints202406.0122.v1
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
Tissue agnostic drug development; Pembrolizumab; Microsatellite instability-high (MSI-H); Tumor mutational burden-high (TMB-H); Dostarlimab-gxly; Larotrectinib; Entrectinib; Neurotrophic tyrosine kinase (NTRK); Dabrafenib and trametinib; V-Raf Murine Sarcoma Viral Oncogene Homolog B V600E (BRAFV600E); Selpercatinib; Rearranged during transfection (RET); Precision oncology.
Online: 3 June 2024 (16:08:38 CEST)