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The Symbiosis of Formal Methods and Artificial Intelligence
Jonathan P. Bowen
Posted: 04 March 2026
Retrieval-Augmented Generation Enhanced GPT-4.1 to Support Clinical Trial Informed Consent Review for Data Reuse
Lameck Mbangula Amugongo
,Lena Schaller
,Maarten van Dijk
,Helene Wendt
,Claudia Neumann
,Andreas Freisinger
,Jaroslaw Deska
Posted: 04 March 2026
The Contribution of Natural Isotopes in Understanding Groundwater Circulation: Case Studies in Carbonate Aquifers of Central Apennines
Alessia Di Giovanni
,Sergio Rusi
Posted: 04 March 2026
Finite Differences of Prime Powers as Cyclotomic Norms: A Structural Bridge from Nicomachus to Euler. Universal Anderson–Faulhaber–Bernoulli Identity: Internal Structure of Perfect Powers and Arithmetic Obstruction via Discrete Calculus
Ibar Federico Anderson
Posted: 04 March 2026
SWEET-RL: Reinforcement Learning for Multi-Turn Collaborative Reasoning with LLM Agents
Arjun K. Sharma
,Priyanka Dasgupta
,Rajesh V. Iyer
Posted: 04 March 2026
Generalized Traub Family for Solving Nonlinear Systems: Fourth-Order Optimal Method and Dynamical Analysis
Alicia Cordero
,Miguel A. Leonardo Sepúlveda
,Juan R. Torregrosa
,Antmel Rodríguez Cabral
,María P. Vassileva
Posted: 04 March 2026
Ontology-Based Validation of Enterprise Architecture Principles
Devid Montecchiari
Posted: 04 March 2026
Amino Acid Dysregulation in the Mother-Fetus Unit: Multi-Compartment Metabolomic Signatures of Gestational Diabetes Mellitus and Fetal Macrosomia
Natalia Frankevich
,Alisa Tokareva
,Anna Derenko
,Vitaliy Chagovets
,Anastasiya Novoselova
,Vladimir Frankevich
,Gennadiy Sukhikh
Posted: 04 March 2026
Experimental Planning for Extraction of Secondary Metabolites from Rauvolfia caffra Sond. Leaves: Biological and Chemical Characterization by Synchronous Fluorescence and Phosphorescence Spectroscopy
Karla Ramos
,Amin Karmali
Posted: 04 March 2026
Gibbs Energy Redistribution Theory (GERT): A Thermodynamically Motivated Expansion History and the Hubble Tension
Veronica Padilha Dutra
Posted: 04 March 2026
A Novel Technique for Hernia Repair Using a UV-Sensitive, Adhesive Biomaterial for Hybrid Mesh Fixation
Piotr Prowans
,Agata Goszczynska
,Gokhan Demirci
,Norbert Czapla
,Piotr Bargiel
,Rabih Samad
,Miroslawa El Fray
Background: Mesh implantation is the standard of care in hernia repair. However, penetrating suture fixation may contribute to chronic pain and tissue irritation. This pilot study evaluates the feasibility of a hybrid fixation technique using a biodegradable UV-curable adhesive biomaterial in inguinal hernia repair.Methods: Ten male patients (20-40 years) with unilateral inguinal hernia underwent open repair and were allocated into two groups (n = 5 each): hybrid fixation approach (part of the mesh was secured conventionally and the remaining portion was stabilized with an experimental adhesive UV-curable biomaterial within 3 minutes) and conventional mesh fixation. Pain (VAS) and patient-reported outcomes (CCS, EuraHS QoL, SF-36) were assessed at day 1, day 8, 6 weeks, 12 months, and 24 months. Ultrasonography and thermography were analysed when available as exploratory assessments.Results: The adhesive-assisted partial self-stabilization reduced operative time compared with conventional fixation (52.0 ± 3.1 vs 60.2 ± 3.7 min). Postoperative pain (VAS) in the hybrid group decreased from 2.6 ± 0.55 on day 1 to 0.8 ± 0.84 on day 8, with complete resolution by 6 weeks. Foreign-body sensation (CCS) decreased from day 1 to 6 weeks in both groups (hybrid: 54.08% to 30.38%, control: 65.32% to 36.57%). No intraoperative complications and no hernia recurrences were observed during the 24-month follow-up. Overall SF-36 scores increased from 77.8 preoperatively to 92.4 at 24 months. Conclusions: In this pilot cohort, hybrid fixation using the UV-curable adhesive was feasible and was associated with shorter operative time, with no intraoperative complications and no recurrences observed during follow-up. Further studies of hybrid mesh fixation on larger cohorts are warranted.
Background: Mesh implantation is the standard of care in hernia repair. However, penetrating suture fixation may contribute to chronic pain and tissue irritation. This pilot study evaluates the feasibility of a hybrid fixation technique using a biodegradable UV-curable adhesive biomaterial in inguinal hernia repair.Methods: Ten male patients (20-40 years) with unilateral inguinal hernia underwent open repair and were allocated into two groups (n = 5 each): hybrid fixation approach (part of the mesh was secured conventionally and the remaining portion was stabilized with an experimental adhesive UV-curable biomaterial within 3 minutes) and conventional mesh fixation. Pain (VAS) and patient-reported outcomes (CCS, EuraHS QoL, SF-36) were assessed at day 1, day 8, 6 weeks, 12 months, and 24 months. Ultrasonography and thermography were analysed when available as exploratory assessments.Results: The adhesive-assisted partial self-stabilization reduced operative time compared with conventional fixation (52.0 ± 3.1 vs 60.2 ± 3.7 min). Postoperative pain (VAS) in the hybrid group decreased from 2.6 ± 0.55 on day 1 to 0.8 ± 0.84 on day 8, with complete resolution by 6 weeks. Foreign-body sensation (CCS) decreased from day 1 to 6 weeks in both groups (hybrid: 54.08% to 30.38%, control: 65.32% to 36.57%). No intraoperative complications and no hernia recurrences were observed during the 24-month follow-up. Overall SF-36 scores increased from 77.8 preoperatively to 92.4 at 24 months. Conclusions: In this pilot cohort, hybrid fixation using the UV-curable adhesive was feasible and was associated with shorter operative time, with no intraoperative complications and no recurrences observed during follow-up. Further studies of hybrid mesh fixation on larger cohorts are warranted.
Posted: 04 March 2026
Multi-Platform LiDAR Comparative Assessment for Above-Ground Biomass and Carbon Estimation in Mediterranean Woody Crops
Mateo Pastrana
,Cristina Velilla
,Nelson Mattie
,Alfonso Gomez
,Sergio Molina
Posted: 04 March 2026
Fast Triangle Detection and Enumeration in Undirected Graphs: The Aegypti Algorithm
Frank Vega
Posted: 04 March 2026
Binary Transformer Detectors for Automatic Modulation Detection Under Realistic Radio Frequency Impairments
AnuraagChandra Singh Thakur
,Masudul Imtiaz
Posted: 04 March 2026
Candidate Gene Discovery for Rust Resistance Through Multi-Locus Genome-Wide Association Study in Groundnut
Hima Bindu Bhadragiri
,Jayashree Kar
,Madhvi Sharma
,H. V. Veerendrakumar
,Digbijaya Swain
,Arabinda Dal
,Sukanta K. Pradhan
,Ragavendran Abbai
,Trinh Xuan Hoat
,Hari K. Sudini
+2 authors
Rust, caused by Puccinia arachidis, is one among the most destructive fungal diseases constraining global groundnut (Arachis hypogaea L.) production. While the development of disease-resistant varieties stands as the most effective approach to preventing substantial yield losses, the genetic mechanisms underlying resistance to rust is not yet well understood, emphasizing the necessity for further detailed research. In this study, 184 accessions from the ICRISAT groundnut mini-core collection were evaluated for rust resistance at Dharwad, India, across multiple seasons, as well as in Vietnam for one season. Whole-genome resequencing-based genome-wide association study (GWAS) identified five highly significant marker trait associations (MTAs) for rust resistance (p = 5.22 × 10-13 to 7.21 × 10-08). Among these, two robust rust-associated kompetitive allele specific PCR (KASP) markers, snpAH00607 at chromosome Ah01 and snpAH00609 at chromosome Ah17, were validated across diverse set of breeding and pre-breeding lines. These markers were linked to candidate genes encoding sterol C4-methyl oxidase 1-2, implicated in brassinosteroid-mediated salicylic acid signalling, and MYB transcription factor known to be associated with defense responses. The identified SNPs, validated markers, and candidate genes will serve as important resources for marker-assisted breeding of rust disease resistant groundnut varieties.
Rust, caused by Puccinia arachidis, is one among the most destructive fungal diseases constraining global groundnut (Arachis hypogaea L.) production. While the development of disease-resistant varieties stands as the most effective approach to preventing substantial yield losses, the genetic mechanisms underlying resistance to rust is not yet well understood, emphasizing the necessity for further detailed research. In this study, 184 accessions from the ICRISAT groundnut mini-core collection were evaluated for rust resistance at Dharwad, India, across multiple seasons, as well as in Vietnam for one season. Whole-genome resequencing-based genome-wide association study (GWAS) identified five highly significant marker trait associations (MTAs) for rust resistance (p = 5.22 × 10-13 to 7.21 × 10-08). Among these, two robust rust-associated kompetitive allele specific PCR (KASP) markers, snpAH00607 at chromosome Ah01 and snpAH00609 at chromosome Ah17, were validated across diverse set of breeding and pre-breeding lines. These markers were linked to candidate genes encoding sterol C4-methyl oxidase 1-2, implicated in brassinosteroid-mediated salicylic acid signalling, and MYB transcription factor known to be associated with defense responses. The identified SNPs, validated markers, and candidate genes will serve as important resources for marker-assisted breeding of rust disease resistant groundnut varieties.
Posted: 04 March 2026
Equity Market Structure and Trading Diversification: Insights from Panel Data, Clustering, and Machine Learning
Angelo Leogrande
,Fabio Anobile
,Alberto Costantiello
,Carlo Drago
,Massimo Arnone
Posted: 04 March 2026
Emergence of a New Human: The Birth of Homo constellatus – Toward a Post-Neurotypical, Cosmically Reintegrated Civilisation
Theodor-Nicolae Carp
Posted: 04 March 2026
Age-Associated Differences in Paddock Locomotor Activity Among Senior Horses: A Pilot Observational Study
Luc Poinsard
,Claire Anson
,Véronique Billat
Posted: 04 March 2026
Investigating the Refactoring Capabilities of Small Open-Weight Language Models
Tamás Márton
,Balázs Szalontai
,Balázs Pintér
,Tibor Gregorics
Posted: 04 March 2026
MultiFixRadSoft: A Comprehensive Tool for Primary Relative Radiometric Scale Realization in Radiation Thermometry
Mehtap Ertürk
,Mevlüt Karabulut
,Ömer Faruk Kadi
,Can Gözönünde
,Patrik Broberg
,Åge Andreas Falnes Olsen
,Humbet Nasibli
Posted: 04 March 2026
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