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Preprint ARTICLE | doi:10.20944/preprints202404.1633.v1

Dynamic Convergence: Exploring AI's Impact on Social Science in Malaysia

FATIN IZZATY SYAMIMI SHASTRIE

Subject: Sociology, Social Sciences Keywords: Human; System; Modernity; Transformations; Digital

Online: 24 April 2024 (16:40:44 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202404.1628.v1

Exploring Intrinsic Disorder in Human Synucleins and Associated Proteins

Sriya Reddy Venati, Vladimir N. Uversky

Subject: Life Sciences, Biology And Life Sciences Keywords: α-synuclein; β-synuclein; γ-synuclein; intrinsically disordered protein; liquid-liquid phase separation; Parkinson’s disease; protein-protein interactions

Online: 24 April 2024 (15:35:56 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202404.1626.v1

Photodegradation of a Broad-Spectrum Antibiotic Azithromycin Using H2O2 under UV Irradiation

Nasser Ibrahim Zouli

Subject: Environmental Science, Environmental And Earth Sciences Keywords: azithromycin; UV irradiation; H2O2; photodegradation; Zero order kinetics

Online: 24 April 2024 (15:34:04 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202404.1621.v1

Implementation of an LSTM Neural Network-based Algorithm for Dynamic Obstacle Avoidance

Esmeralda Mulás-Tejeda, Alfonso Gómez-Espinosa, Jesús Arturo Escobedo Cabello, Jose Antonio Cantoral-Ceballos, Alejandra Molina-Leal

Subject: Electrical And Electronic Engineering, Engineering Keywords: Mobile robot; obstacle avoidance; dynamic environment; neural networks; artificial intelligence.

Online: 24 April 2024 (15:32:25 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202404.1625.v1

Triple Negative Breast Cancer Subclassified by Immunohistochemistry: Correlation with Clinical and Pathological Outcomes in Patients Receiving Neoadjuvant Chemotherapy

Bruno de Paula, Susanne Crocamo, Carlos Sousa, Priscila Valverde Fernandes, Fabiana Rezende, Eliana Abdelhay

Subject: Oncology And Oncogenics, Medicine And Pharmacology Keywords: triple negative breast cancer; immunohistochemistry; neoadjuvant chemotherapy

Online: 24 April 2024 (15:29:37 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202309.2119.v2

Ocular Neuromodulation as a Novel Treatment for Retinitis Pigmentosa: Identifying Rod Responders and Predictors of Visual Improvement

Ismail Mohammed Musallam

Subject: Neuroscience And Neurology, Biology And Life Sciences Keywords: Retinitis pimentosa; Ocular neuromodulation; Ophthalmic nerve stimulation; Ascorbic acid; Rod responders; Substance P; Night blindness

Online: 24 April 2024 (15:25:40 CEST)

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Starvation of photoreceptors induced by reduced dysregulated ocular blood flow is proposed as a common pathway for the pathogenesis of retinitis pigmentosa (RP). The current study evaluated the safety and efficacy of ophthalmic nerve stimulation (ONS) as an ocular blood flow neuromodulator, combined with ascorbic acid (AA) as a potent anti-oxidant in the treatment of RP. Additionally, the initial characteristics of rod responders were identified. Forty participants with simple, non-syndromic RP presented with a characteristic triad of RP (the bone spicule pigmentation, attenuation of retinal blood vessels, and waxy optic disc pallor), were en-rolled in a prospective open-label single-armed interventional study. The severity of the disease was clinically graded into six stages. Patients with an established diagnosis of RP; aged ≥ 4 years, with best corrected visual acuity (BCVA) ≥ 20/400 were included. All participants were daily treated with bilateral ONS sessions combined with intravenous administration of AA for two weeks. The primary efficiency endpoint was 6 months’ changes in scotopic vision as measured by a 10-item, 100-point, Low Luminance Questionnaire-10 (LLQ-10). The secondary efficiency points included best corrected visual acuity (BCVA) and contrast sensitivity. Rod responders were defined by ≥ 25 points increment of LLQ-10 score at 6 months after treatment. The results showed that ONS combined with AA treatment significantly improved low luminance vision, BCVA, and contrast sensitivity in patients with RP (p≤ 0.05). At 6-month visit, twenty-four (60%) patients were identified as rod responders and 16 (40%) patients were rod-non-responders. The mean change in LLQ-10 score was (46.35 ±16.81) in rod responders versus (4.9 ± 7.6) in non-responders (p < 0.0001). A clinically significant improvement of BCVA (≥0.2 logMAR) and contrast sensitivity (≥0.3 log unit) were demonstrated in 50% of the right eyes of rod responders. No serious adverse effects were reported and headache in 5 patients (12.5%) was the only en-countered side effect in this study. In conclusion, ocular neuromodulation is a safe therapeutic strategy for RP. It significantly improved night vision, BCVA, and contrast sensitivity. Determinants of rod responders include a shorter duration of night blindness, an earlier stage of the disease, and a relatively thicker ganglion cell layer at baseline. Additionally, two therapeutic scenarios were recognized; an early disease-modifying intervention that restores night vision and reverses the disease process and a late cone rescue intervention that improves/maintains central vision.

Preprint ARTICLE | doi:10.20944/preprints202404.0357.v3

The Path to Data Protection Governance in China Mainland

Bing Chen, Yongji Liu

Subject: Law, Social Sciences Keywords: data protection; personal privacy; cybersecurity; data security

Online: 24 April 2024 (14:20:16 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202404.1608.v1

Mental Health and Substance Use Disorders in Transplant Waitlist, VAD, and Heart Transplant Patients: A TriNetX Database Analysis

Chloe Grzyb, Dongping Du, Balakrishnan Mahesh, Nandini Nair

Subject: Cardiac And Cardiovascular Systems, Medicine And Pharmacology Keywords: substance use; cardiac transplant; VAD; mental health

Online: 24 April 2024 (14:14:51 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202404.1611.v1

Recurrent Incisional Hernia; Cases Operated with the Use of the Existing Integrated Prosthesis

Daniel Ioan Mihalache, Niculae Iordache, Marius Florin Dragoescu

Subject: Clinical Medicine, Medicine And Pharmacology Keywords: incisional hernia, recurrent eventration, existing prosthesis, selection criteria

Online: 24 April 2024 (14:13:08 CEST)

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Preprint COMMUNICATION | doi:10.20944/preprints202404.1453.v2

The G-Protein-Coupled Estrogen Receptor Selective Agonist G-1 Attenuates Cell Viability and Migration in High-Grade Serous Ovarian Cancer Cell Lines

Donia Hanafi, Rob U Onyenwoke, K Sean Kimbro

Subject: Biochemistry And Molecular Biology, Biology And Life Sciences Keywords: GPER receptor; Therapeutic; Fallopian Tubes; Ovarian Cancer

Online: 24 April 2024 (14:11:35 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202404.1607.v1

Mechanism of Surface Hydroxylation Acceleration and Laser-Induced Damage Threshold Reduction during Ion Beam Sputtering of Fused Silica

Mingjin Xu, Weibin Wu, Yongsheng Ke, Xiaohong Liu, Yaoyu Zhong, Xiaopeng Gao

Subject: Mechanical Engineering, Engineering Keywords: ion beam sputtering; laser damage; hydroxyl groups; surface hydroxylation; chemical structure defect

Online: 24 April 2024 (14:10:16 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202404.1606.v1

A Primer on Dominance Analysis

Felix Bittmann

Subject: Probability And Statistics, Computer Science And Mathematics Keywords: dominance analysis; regression; variance decomposition

Online: 24 April 2024 (14:06:37 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202404.1624.v1

Using Cooking Schools to Improve the Pleasure of Food and Cooking in Patients Experiencing Smell Loss

Alexander Wieck Fjaeldstad

Subject: Otolaryngology, Medicine And Pharmacology Keywords: Olfaction; Rehabilitation; Anosmia; Hyposmia

Online: 24 April 2024 (12:09:44 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202404.1623.v1

Effects of Water Quality on Diversity of Freshwater Green Microalgae in Semiurban Areas

Chitralekha Nag Dasgupta, Sanjeeva Nayaka, Atul Kumar Singh

Subject: Aquatic Science, Biology And Life Sciences Keywords: Diversity index; Distribution pattern; Green algae; Taxonomic identification; Water parameter

Online: 24 April 2024 (11:53:06 CEST)

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Preprint COMMUNICATION | doi:10.20944/preprints202404.1622.v1

Refractive Index and Dispersion Measurement with Polarization Change in Total Internal Reflection

Jyung-Ping Chang, Cheng-Mu Tsai, Jun-Hong Weng, Pin Han

Subject: Optics And Photonics, Physical Sciences Keywords: refractive index measurement; total internal reflection; polarization change; material dispersion

Online: 24 April 2024 (11:49:28 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202404.1609.v1

Study on Body Weight-Length Relationship and Relative Fatness of Bigeye Grunt Brachydeuterus auritus in the Coastal Waters off Sierra Leone

Guoqing Zhao, Xin Rao, Shuai Li, Jialiang Yang, Lingzhi Li, Hongliang Huang

Subject: Aquatic Science, Biology And Life Sciences Keywords: bigeye grunt; body-length weight relationship; relative fatness; environment factor; Sierra Leone

Online: 24 April 2024 (11:49:14 CEST)

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Bigeye grunt Brachydeuterus auritus is an important economic species in the waters off Sierra Leone in West Africa, with great ecological value. Based on the survey data of bottom trawl nets from 6 voyages from 2019 to 2021, the body weight-length relationship (WLR), as well as their relative fatness, were studied in depth using the method of body length and its corresponding mean body weight. This study fitted the WLR of bigeye grunt by gender, calculated its fullness, and analyzed the influence of environmental factors. The results showed that month and gender had a significant impact on body length and weight distribution (P<0.01). There was a highly significant negative correlation (P<0.01) between the condition factor (a) and the allometric factor (b) in the WLR, and salinity significantly affects b (P<0.05). The (lga)/b ratio was less affected by environmental factors which may be related to the body size and density of the fish. The difference in b between male and female populations was extremely significant (P<0.01). The relative fatness had significant seasonal variation characteristics, with highly significant effects of sex and body length (P<0.01). With increasing body length, the relative fatness showed two types of changes, continuously increasing and first increasing then decreasing, with salinity and b significantly affecting the type of change (P<0.05) and depth having a highly significant effect (P<0.01). The bigeye grunt off the coast Sierra Leone exhibited significant seasonal growth characteristics, with significant differences in growth characteristics between male and female individuals. This study suggested that salinity may be the main factor affecting its growth and development. In addition, this study hypothesised that the peak breeding season may occur during the dry season, beginning in December and ending before April of the following year. The study provides updated and more comprehensive insights into the biology and ecology of the bigeye grunt offshore Sierra Leone, West Africa, which can provide scientific basis for its resource assessment, development and utilization, and resource management.

Preprint ARTICLE | doi:10.20944/preprints202404.1602.v1

Comparison of Breast Sensibility Following Breast Reconstruction With Two Different Techniques: DIEP Flap and Expander/Implant

Soraya Tadimi Tazi

Subject: Surgery, Medicine And Pharmacology Keywords: Breast sensibility; Breast reconstruction; DIEP abdominal flap; Implant; Semmes-Weinstein monofilaments; Thermal discrimination; Quality of life, BREAST-Q.

Online: 24 April 2024 (11:48:01 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202404.1601.v1

Mitigating Threats in LoRaWAN Air Pollution Monitoring: Blockchain-Integrated Wireless Security for Azores Archipelago

Nick Nguyen, Sean Venezia, Joshua K Davis, Orlando Baiocchi, DC Grant

Subject: Other, Engineering Keywords: LoRaWan; Blockchain; Lightweight Scalable Blockchain; IoT devices; consensus mechanism; transaction processing

Online: 24 April 2024 (11:46:01 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202402.1109.v2

Estimating Wastewater Dilution Using Chemical Markers and Incomplete Flow Measurements: Application to Normalisation of SARS-CoV-2 Measurements

Owen D. Jones, Amy J. Baldwin, William B. Perry, Henry Wilde, Isabelle Durance, Davey L. Jones, Andrew Weightman

Subject: Water Science And Technology, Environmental And Earth Sciences Keywords: SARS-CoV-2; wastewater-based epidemiology; wastewater; dilution; flow normalisation; Bayesian

Online: 24 April 2024 (11:44:50 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202404.1612.v1

BUB1 Inhibition Sensitizes TNBC Cell Lines to Chemotherapy and Radiotherapy

Sushmitha Sriramulu, Shivani Thoidingjam, Farzan Siddiqui, Stephen L Brown, Benjamin Movsas, Eleanor Walker, Shyam Nyati

Subject: Oncology And Oncogenics, Medicine And Pharmacology Keywords: TNBC; BAY1816032; BUB1; PARP; olaparib; cisplatin; paclitaxel; radiation; chemoradiation

Online: 24 April 2024 (11:35:50 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202404.1615.v1

Adherence to Antiretroviral Therapy (ART) Among HIV-1 Patients From Sub-Saharan Africa: A Systematic Review

Cruz Sebastião, Carlos Rafael, Victor Pimentel, Ana Abecasis, Joana Morais

Subject: Public Health And Health Services, Public Health And Healthcare Keywords: HIV-1; Antiretroviral therapy; Treatment adherence; sub-Saharan Africa.

Online: 24 April 2024 (11:35:33 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202404.1610.v1

Inheritance of Mitochondria in Pelargonium Section Ciconium (Sweet) Interspecific Crosses

Floris C. Breman, Joost Korver, Ronald Snijder, Eric Schranz, Freek T. Bakker

Subject: Ecology, Evolution, Behavior And Systematics, Biology And Life Sciences Keywords: Pelargonium; mitochondrion; inheritance; CNI; Ciconium

Online: 24 April 2024 (11:31:28 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202404.1618.v1

Short-Term Clinical Results of Minimally Invasive Direct Coronary Artery Bypass (MIDCAB) Procedure

Eissa Alaj, Vahid Seidiramool, Veaceslav Ciobanu, Farhad Bakhtiary, Nadejda Monsefi

Subject: Cardiac And Cardiovascular Systems, Medicine And Pharmacology Keywords: minimally invasive cardiac surgery; , coronary artery bypass; offpump; endoscopic harvesting of mammary artery

Online: 24 April 2024 (11:06:36 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202404.1616.v1

Design and Analysis of Novel Anti-rocking Bearing

Yuqing Yang, Fanchang Kong, Longgui Bu, Zaigen Mu

Subject: Civil Engineering, Engineering Keywords: Novel anti-rocking bearing; Steel tension rod; Steel spring; Seismic time history analysis

Online: 24 April 2024 (11:05:23 CEST)

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Preprint CONCEPT PAPER | doi:10.20944/preprints202404.1620.v1

Microglial Replacement and COURIER or SPIT for Neuronal Gene Editing

Michael Renteln

Subject: Biology And Biotechnology, Biology And Life Sciences Keywords: microglial replacement; adeno-associated viral (AAV) vectors; COURIER; SPIT; base editing; prime editing

Online: 24 April 2024 (11:05:05 CEST)

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Preprint CASE REPORT | doi:10.20944/preprints202404.1619.v1

Case Report: Eliminating Dairy as a Novel Treatment in Acne Vulgaris

Olnita Martini, Elizabeth Tchernogorova, Ryan Cox, Parker Miller, Mary Tidwell, Nicole Skalka, Alexandra Ortiz-Jimenez, Benjamin Brooks

Subject: Dermatology, Medicine And Pharmacology Keywords: acne vulgaris; dermatology; acne treatment; cystic acne

Online: 24 April 2024 (11:04:26 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202404.1617.v1

Quantum Retarded Field Engine

Asher Yahalom

Subject: Quantum Science And Technology, Physical Sciences Keywords: Retardation; Relativity; Quantum Mechanics

Online: 24 April 2024 (10:12:05 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202404.1604.v1

A Acylhydrazone Compound A5 Promotes Neurogenesis by Up-regulating Neurogenesis-related Genes and Inhibiting Cell-cycle Progression in Neural Stem/Progenitor Cells

Xiaoliang Xiang, Xia Jiang, Hongwei Lin, Meixing Yu, Liming Wu, Rong Zhou

Subject: Neuroscience And Neurology, Medicine And Pharmacology Keywords: acylhydrazone compound; neural stem/progenitor cells; neurogenesis; cell-cycle progression; neurodegenerative diseases

Online: 24 April 2024 (10:07:46 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202404.1597.v1

Deciphering the Interplay: Thieno[2,3-b]pyridine Impact on Glycosphingolipid Expression, Cytotoxicity, Apoptosis, and Metabolomics in Ovarian Tumor Cell Lines

Zdravko Odak, Sandra Marijan, Mila Radan, Lisa I. Pilkington, Monika Čikeš Botić, David Barker, Jóhannes Reynisson, Vedrana Čikeš-Čulić

Subject: Biochemistry And Molecular Biology, Biology And Life Sciences Keywords: ovarian cancer, glycosphingolipids (GSLs), apoptosis, cytotoxicity, metabolomics, thieno[2,3-b]pyridine, cancer stem cells (CSCs)

Online: 24 April 2024 (10:06:01 CEST)

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Preprint TECHNICAL NOTE | doi:10.20944/preprints202404.1595.v1

Get Free Copy: A Multi-Repository Search Platform for Biomedical Publications

Nodir Kosimkhujaev, Kuan-lin Huang

Subject: Other, Biology And Life Sciences Keywords: open science; preprint; web platform

Online: 24 April 2024 (10:03:29 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202404.1598.v1

Analysis of Dynamic Behavior of Multi-layer Soil Grounds Through 1 G Shaking Table Tests and Numerical Analysis

Yong Jin, Sugeun Jeong, Minseo Moon, Daehyeon Kim

Subject: Civil Engineering, Engineering Keywords: ground; seismic; dynamic behavior; response; 1 g shaking table; numerical analysis; multi-layered; amplification

Online: 24 April 2024 (10:02:28 CEST)

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Preprint CONCEPT PAPER | doi:10.20944/preprints202404.1563.v1

FEDSTR: Money-In AI-Out | A Decentralized Marketplace for Federated Learning and LLM Training on the NOSTR Protocol

Konstantinos Nikolakakis, George Chantzialexiou, Dionysis Kalogerias

Subject: Artificial Intelligence And Machine Learning, Computer Science And Mathematics Keywords: distributed; parallel; and cluster computing; social and information networks; federated learning; LLMs; communication protocols

Online: 24 April 2024 (10:00:25 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202404.1555.v1

Unveiling the Nexus: Sulphur Dioxide Exposure, Proximity to Mining, And Respiratory Illnesses in Kankoyo: A Mixed-Methods Investigation

Sipiwe Chihana, Jameson Mbale, Nchimunya Chaamwe

Subject: Public, Environmental And Occupational Health, Public Health And Healthcare Keywords: Sulphur Dioxide Exposure; Mining and Health Impact; Respiratory Illnesses; Community 9 Health Monitoring; Mixed-Methods Research; Air Pollution

Online: 24 April 2024 (09:59:14 CEST)

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The emission of sulphur dioxide (SO2) from mining activities presents a substantial risk to public health, especially in populations located near mine industrial regions. This study investigated the potential correlation between exposure to sulphur dioxide (SO2) and its effects on respiratory health in Kankoyo Township, Zambia. A variety of methodologies were employed in this study, encompassing community participation, expert interviews, spatial analysis, and a retrospective examination of health and SO2 data for Kankoyo spanning 15 years. The results of our research indicated a worrisome correlation between the community and the presence of SO2, which has had a significant impact on their lives. The expert interviews also emphasized the effects of SO2, with respiratory cases accounting for approximately 75% of the reported cases. Additionally, the clinic officer observed that asthma cases have decreased following the implementation of a monitoring station in the community. Furthermore, overall emissions of SO2 have decreased since the upgrade of the smelter operation. A probable association was identified in the retrospective analysis between exposure to SO2 and the occurrence of asthma, respiratory non-pneumonia, and pneumonia infections. The findings of the retrospective research revealed a substantial association between SO2 concentrations and the susceptibility of individuals aged 5 years and older to asthma, respiratory non-pneumonia, and pneumonia infections. The results of the spatial study indicated that Kankoyo exhibited a significant level of SO2 pollution, above the established limitations set by the Zambian Environmental Management Agency (ZEMA) by an alarming margin of 1713%. In response to the challenges identified, this study proposed several measures. These measures encompassed the implementation of a requirement for regulators such as ZEMA and local communities to have access to real-time pollution data from mines, to enhance transparency. Additionally, the deployment of affordable air quality sensors, the resolution of medication shortages, the establishment of specialized respiratory health clinics, the initiation of IT-driven public awareness campaigns, and the expansion of research to investigate additional pollutants and confounding factors were also recommended.

Preprint COMMUNICATION | doi:10.20944/preprints202404.1562.v1

Clip Closure and PuraStat for Prevention of Clinically Significant Delayed Bleeding after Colorectal Endoscopic Submucosal Dissection: A Prospective, Observational Study

Mihai Ciocirlan, Dana Bilous, Andrei Gila, Daniel Corneliu Leucuta, Daniela Elena Mihaila, Adrian Tulin, Anca Gheorghiu, Elena Tianu, Catalina Vladut

Subject: Gastroenterology And Hepatology, Medicine And Pharmacology Keywords: endoscopic submucosal dissection; clip closure; PuraStat; muscle retracting sign; colorectal mixed neuroendocrine carcinoma

Online: 24 April 2024 (09:58:17 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202404.1588.v1

Orthologs of NOX5 and EC-SOD/SOD3: dNox and dSod3 Impact Egg Hardening Process and Egg Laying in Reproductive Function of Drosophila melanogaster

Eva Louise Louise Steinmetz, Annika Scherer, Célestine Calvet, Uli Müller

Subject: Cell And Developmental Biology, Biology And Life Sciences Keywords: NADPH oxidase 5 (NOX5); (extracellular) superoxide dismutase (EC-SOD or SOD3)

Online: 24 April 2024 (09:57:15 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202404.1592.v1

Self-Powered Acceleration Sensor for Distance Prediction via Triboelectrifications

Zhengbing Ding, Dinh Cong Nguyen, Hakjeong Kim, Xing Wang, Kyungwho Choi, Jihae Lee, Dukhyun Choi

Subject: Other, Engineering Keywords: triboelectric nanogenerator; self-powered; acceleration sensor; distance prediction

Online: 24 April 2024 (09:56:36 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202404.1600.v1

GPTs or Grim Position Threats? The Potential Impacts of Large Language Models on Non-Managerial Jobs and Certifications in Cybersecurity

Raza Nowrozy

Subject: Artificial Intelligence And Machine Learning, Computer Science And Mathematics Keywords: cybersecurity; skills; ChatGPT; workforce; large language model; generative AI

Online: 24 April 2024 (09:46:46 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202404.1593.v1

Demographic Characteristics of an Expanding Iberian Wild Goat Population in Southern Pyrenees, Spain

Juan Herrero, Alicia García-Serrano, Carlos Prada, Ricardo García-González

Subject: Animal Science, Veterinary Science And Zoology, Biology And Life Sciences Keywords: escape; reintroduction; recovery; hybridization.

Online: 24 April 2024 (09:44:35 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202404.1559.v1

Jesmanowicz Conjecture and Gaussian Integer Ring

Nianrong Feng, Junyu Cao, Yongzheng Wang

Subject: Algebra And Number Theory, Computer Science And Mathematics Keywords: Jesmanowicz conjecture; Diophantine equation; Gaussian integer ring; 4k+1 type prime number

Online: 24 April 2024 (09:32:50 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202404.1589.v1

Investigation of the Possibility of Using Coal Flotation Waste in the Production of Agglomerate

IRSHEK Ibraev, Orazbike Ibraeva, Нурбек Айткенов, Kamalchan Sakipov K.E.

Subject: Metallurgy And Metallurgical Engineering, Engineering Keywords: flotation waste
dewatering
agglomeration
recycling
pelletizing

Online: 24 April 2024 (08:58:36 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202404.1554.v1

Exogenous Cytokinin 4-PU-30 Modulates the Response of Wheat and Einkorn Seedlings to UV-B Radiation

Elisaveta Kirova, Irina Moskova, Vasilissa Manova, Yana Koycheva, Zoia Tsekova, Denitsa Borisova, Hristo Nikolov, Ventzeslav Dimitrov, Iskren Sergiev, Konstantina Kocheva

Subject: Plant Sciences, Biology And Life Sciences Keywords: antioxidant gene expression; flavonoids; oxidative stress; phenolic compounds; phenylurea-cytokinin; proline; remote sensing; ROS; spectral reflectance

Online: 24 April 2024 (08:58:18 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202404.1565.v1

Circulating Anti-endothelial Cell Antibodies in Patients with Geographic Atrophy Related to Dry Age-Related Macular Degeneration

Katarzyna Żuber-Łaskawiec, Joanna Wilańska, Izabella Karska-Basta, Weronika Pociej-Marciak, Bożena Romanowska-Dixon, Marek Sanak, Agnieszka Kubicka-Trząska

Subject: Ophthalmology, Medicine And Pharmacology Keywords: anti-retinal antibodies; anti-endothelial cell antibodies; age-related macular degeneration; geographic atrophy; indirect immunofluorescence

Online: 24 April 2024 (08:57:21 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202404.1578.v1

First Account of Epibiotic Diatoms Taxa from the Shells of Green Swimming Crabs Callinectes bellicosus (Stimpson 1859) (Decapoda, Portunidae)

Francisco Omar López-Fuerte, David Alfaro Siqueiros Beltrones, Luis Hernández, Sergio Flores-Ramírez

Subject: Aquatic Science, Biology And Life Sciences Keywords: benthic diatoms; coastal lagoon; crustaceans; epibiosis; Mexico

Online: 24 April 2024 (08:31:48 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202404.1582.v1

Merits of Multi-Indicator Precautionary Approach Management in a Male-Only Crab Fishery

Darrell Mullowney, Krista Baker, Julia Pantin, William Coffey, Kyle Lefort, Katie Morrissey

Subject: Aquatic Science, Biology And Life Sciences Keywords: snow crab; Newfoundland and Labrador; fisheries management; Precautionary Approach; male-only fishery

Online: 24 April 2024 (08:31:01 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202404.1599.v1

Techno-Feasibility Assessment of a Floating Breakwater Concept for Supporting Marine Renewables in Deep Waters

Andrew Borg, Charise Cutajar, Tonio Sant, Robert N. Farrugia, Daniel Buhagiar

Subject: Marine Engineering, Engineering Keywords: floating breakwaters; multi-use offshore space; offshore hydro-pneumatic energy storage; offshore renewables

Online: 24 April 2024 (08:30:40 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202404.1574.v1

Enhancing Multimodal Emotion Recognition through Attention Mechanisms in BERT and CNN Architectures

Fazliddin Makhmudov, Alpamis Kultimuratov, Young-Im Cho

Subject: Artificial Intelligence And Machine Learning, Computer Science And Mathematics Keywords: Deep learning; CNN; BERT; Emotion recognition

Online: 24 April 2024 (08:29:13 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202404.1576.v1

Combustion Characteristics, Kinetics and Thermodynamics of Peanut Shell for Its Bioenergy Valorization

Jialiu Lei, Xiaoyu Liu, Biao Xu, Zicong Liu, Yongjun Fu

Subject: Energy And Fuel Technology, Engineering Keywords: combustion characteristics; kinetics and thermodynamics; thermogravimetric analysis; peanut shell

Online: 24 April 2024 (08:28:48 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202404.1596.v1

Analysis Methodology for the Evaluation of Energy Efficiency and Energy Classification of Buildings in the Residential Sector

María Adelaida Pavón Tapia, Diego Carmona Fernández, Dorotea Dimitrova Angelova, Juan Félix González González

Subject: Energy And Fuel Technology, Engineering Keywords: Energy efficiency; energy rating; energy analysis; residential sector; data processing

Online: 24 April 2024 (08:28:34 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202404.1571.v1

The Key Sustainable Strategies Criteria for Effective Human Resource Management Practices

Ahmed Khalid Alrashedi

Subject: Human Resources And Organizations, Business, Economics And Management Keywords: Human Resources; Organizational Culture; Governance; Culture; Ethics

Online: 24 April 2024 (08:28:27 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202404.1573.v1

Chaotic Instability of Oscillations in Microwave Power Amplifierswhen Amplifying a Biharmonic Signal

L.A. Morozova, S.V. Savel'ev

Subject: Applied Physics, Physical Sciences Keywords: chaos; power amplifier; biharmonic signal; sequence of oscillation trains; chaotic modulation

Online: 24 April 2024 (08:28:11 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202404.1590.v1

How to Cristallize a Glass with a Femtosecond Laser

Ruyue QUE, Matthieu Lancry, Maxime Cavillon, Bertrand Poumellec

Subject: Other, Engineering Keywords: laser induced crystallization in glass; crystallization of oxyde glasses; femtosecond laser

Online: 24 April 2024 (08:28:02 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202404.1605.v1

Impact and Mechanism of High Standard Farmland Construction on Farmland Abandonment: A Moderated Mediating Analysis

Yuhan Zhang, Xu Zhang, Wangyue Zhou, Jianfu Li, Zhenlin Weng, Xueping Gao

Subject: Soil Science, Environmental And Earth Sciences Keywords: high-standard farmland construction; farmland abandonment; agricultural socialization services; agricultural labor transfer distance; moderated mediating effect

Online: 24 April 2024 (08:25:21 CEST)

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Preprint REVIEW | doi:10.20944/preprints202404.1584.v1

Silver Fir (Abies alba Mill.): Review of Ecological Insights, Forest Management Strategies, and Climate Change Impact on European Forests

Michal Bledý, Stanislav Vacek, Pavel Brabec, Zdeněk Vacek, Jan Cukor, Jakub Černý, Richard Ševčík, Kateřina Brynychová

Subject: Forestry, Biology And Life Sciences Keywords: Forest management; Silver fir ecology; Climate change impact; Biodiversity; Threats and diseases; Regeneration practices

Online: 24 April 2024 (07:30:44 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202404.1561.v1

Peptide-Purified Anti-N-Methyl-D-Aspartate (NMDA) Receptor Autoantibodies Have Inhibitory Effect on Long-Term Synaptic Plasticity

Charlotte Day, John-Paul Silva, Rebecca Munro, Brice Mullier, Véronique Marie André, Christian Wolff, Gary John Stephens, Angela Bithell

Subject: Neuroscience And Neurology, Medicine And Pharmacology Keywords: NMDA receptor autoantibodies; hippocampal neuron; long-term potentiation; multi-electrode arrays

Online: 24 April 2024 (07:28:24 CEST)

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Recent studies, typically using patient cerebrospinal fluid (CSF), have suggested that different autoantibodies (Aabs) acting on their respective receptors, may underlie neuropsychiatric disorders. The NR1 subunit of the N-methyl-D-aspartate receptor (NMDAR) has been identified as a target of anti-NMDAR Aabs in a number of central nervous system (CNS) diseases including encephalitis and autoimmune epilepsy. However, the role or the nature of Aabs responsible for effects on neuronal excitability and synaptic plasticity is yet to be established fully. Patient-derived anti-NMDAR Aabs have been shown to bind to specific regions within the NR1 subunit; here, peptide immunisation was used to generate Aabs against selected specific NR1 extracellular sequences. ‘Protein A’ purification was used to obtain total IgG and further peptide purification used to obtain a greater percentage of NMDAR-target specific IgG Aabs. Binding and specificity of these anti-NMDAR Aabs was determined using a range of methodologies including enzyme-linked immunosorbent assay, immunocytochemistry and immunoblotting. Functional effects were determined using different in vitro electrophysiology techniques: two-electrode voltage-clamp in Xenopus oocytes and measures of long-term potentiation (LTP) in ex vivo hippocampal brain slices using multi-electrode arrays. We show that anti-NMDAR Aabs generated from peptide immunisation had specificity for NR1 immunisation peptides as well as target-specific binding to the native protein. Anti-NMDAR Aabs had no clear effect on isolated NMDARs in an oocyte expression system. However, we show that peptide-purified anti-NMDAR Aabs prevented the induction of LTP at Schaffer collateral-CA1 synapses in ex vivo brain slices. Our data demonstrate that anti-NMDAR Aabs cause synaptic NMDAR hypofunction at a network level. This work provides a solid basis to address outstanding questions regarding anti-NMDAR Aabs mechanisms of action and, potentially, development of therapies against CNS diseases.

Preprint ARTICLE | doi:10.20944/preprints202404.1542.v1

Attitudes of Healthcare Professionals in an Autonomous Community in Spain towards Paediatric Influenza Vaccination

Jaime Jesús Pérez-Martín, Antonio Iofrío de Arce, Matilde Zornoza-Moreno

Subject: Pediatrics, Perinatology And Child Health, Medicine And Pharmacology Keywords: Influenza vaccines; Healthcare professional; Attitude of Healthcare professional; intramuscular vaccine; Inhaled vaccine

Online: 24 April 2024 (07:26:27 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202404.1543.v1

Water-Light Interaction and its Effect on the Morphophysiology of Cedrela fissilis Vell Seedlings

Juliana Milene Silverio, Silvana de Paula Quintão Scalon, Cleberton Correia Santos, Jessica Aline Linné, Anderson dos Santos Dias, Rodrigo da Silva Bernardes, Thaise Dantas

Subject: Agricultural Science And Agronomy, Biology And Life Sciences Keywords: cedro; abiotic stress; phenotypic plasticity; photosynthetic metabolism

Online: 24 April 2024 (07:24:50 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202404.1560.v1

Calibration and Modelling of the Semmes-Weinstein Monofilament for Diabetic Foot Management

Pedro Castro-Martins, Luis Coelho, R.D.S.G. Campilho

Subject: Bioengineering, Engineering Keywords: Diabetic Foot; Monofilament; Metrological Verification; Buckling Force

Online: 24 April 2024 (07:22:36 CEST)

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Preprint COMMUNICATION | doi:10.20944/preprints202404.1556.v1

Impacts of the Methylated Cyclodextrin KLEPTOSE® CRYSMEB on Inflammatory Responses in Human In Vitro Models

Damien Truffin, Flora Marchand, Mathias Chatelais, Gérald Chêne, Laure Saias, Frauke Herbst, Justin Lipner, Alastair King

Subject: Immunology And Allergy, Medicine And Pharmacology Keywords: Methylated Cyclodextrin; Cyclodextrin; KLEPTOSE® CRYSMEB; anti-inflammatory; immunity; HUVEC; BCS; T cell; Diversity PLUS® Panel; chemokines; polyunsaturated fatty acid; lipoxins; resolvins; maresins; protectins; Peripheral Blood Mononuclear Cell, screening; cytokine

Online: 24 April 2024 (07:09:16 CEST)

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Preprint REVIEW | doi:10.20944/preprints202404.1519.v1

Novel Technologies towards the Implementation and Exploitation of “Green” Wireless Agriculture Sensors

Loukia Vassiliou, Adnan Nadeem, David Chatzichristodoulou, Photos Vryonides, Symeon Nikolaou

Subject: Electrical And Electronic Engineering, Engineering Keywords: precision agriculture; additive manufacturing; humidity sensors; RFID sensors; WPT; UAVs; energy harvesting; beamforming; battery-less wireless sensors

Online: 24 April 2024 (06:37:31 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202404.1572.v1

Predictive Factors Associated with Future Decline in Swallowing Function among Japanese Older People Aged ≥ 75 Years

Komei Iwai, Tetsuji Azuma, Takatoshi Yonenaga, Yasuyuki Sasai, Yoshinari Komatsu, Koichiro Tabata, Taketsugu Nomura, Iwane Sugiura, Yujo Inagawa, Yusuke Matsumoto, Seiji Nakashima, Yoshikazu Abe, Takaaki Tomofuji

Subject: Public Health And Health Services, Public Health And Healthcare Keywords: biting; choking; dry mouth; periodontal pocket depth; swallowing function; longitudinal study

Online: 24 April 2024 (06:36:46 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202404.1525.v1

Comparison of Vegetarian Sausages: Proximal Composition, Instrumental Texture, Descriptive Sensory Profile and Overall Liking with Consumers

Karen Carhuancho-Colca, Reynaldo J. Silva-Paz, Carlos Elías-Peñafiel, Bettit K Salvá-Ruiz, Christian R. Encina-Zelada

Subject: Bioengineering, Engineering Keywords: Overall liking; texture profile analysis; purchase intention; flash profile; vegan; descriptors

Online: 24 April 2024 (06:35:39 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202404.1577.v1

Motion Simulation of Landslides Triggered by Earthquakes Using LS-RAPID Program

ZHOU RONG

Subject: Geophysics And Geology, Environmental And Earth Sciences Keywords: Earthquake-induced landslides; Rapid and long-runout; Flow-like; Computer simulation; Motion process.

Online: 24 April 2024 (05:22:26 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202401.0917.v2

The Effect of Different Seeding and Fertilizer Rates on Agronomic Traits, Yield and Yield Components of Two Fodder Oat(Avena Sativa) Varieties in Highlands of North Shewa, Oromia, Ethiopia

Zinash Amare, Metekia Tamiru, Tesfaye Aredo Alemu, Tamrat Dinkale

Subject: Animal Science, Veterinary Science And Zoology, Biology And Life Sciences Keywords: bate; biomass; bona-bas; dry matter; nitrogen; oat; seed

Online: 24 April 2024 (05:21:06 CEST)

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Preprint BRIEF REPORT | doi:10.20944/preprints202404.1580.v1

Association of Hepatitis B Virus E Antigen With HBV Viral Load in Botswana

Lebogang Othusitse, Bonolo B. Phinius, Kutlo Wateka, Gorata Mpebe, Wonderful T. Choga, Lynnette Bhebhe, Basetsana Phakedi, Doreen Ditshwanelo, Tsholofelo Ratsoma, Kabo Baruti, Mosimanegape Jongman, Kebaneilwe Lebani, Sikhulile Moyo, Motswedi Anderson, Simani Gaseitsiwe

Subject: Virology, Biology And Life Sciences Keywords: Hepatitis B virus; HBeAg; HBV viral load; HIV; Botswana

Online: 24 April 2024 (05:18:12 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202404.1569.v1

A Heuristic Scheduling Algorithm in Cloud-Based Additive Manufacturing; an Approach to Using Critical Chain Buffer Management Technique

Shakib Zohrehvandi, Lucia Knapčíková

Subject: Industrial And Manufacturing Engineering, Engineering Keywords: Heuristic Scheduling Algorithm (HSA); Cloud-Based Additive Manufacturing (CBAM); Critical Chain Buffer Management (CC/BM).

Online: 24 April 2024 (05:17:07 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202404.1591.v1

Digital Risk and Financial Inclusion: Balance between Auxiliary Innovation and Protecting Digital Banking Customers

Faraz Ahmed, Arsalan Hussain, Sajjad Nawaz Khan, Arsalan Haneef Malik, Muhammad Asim, Sadique Ahmad, Mohammed El-Affendi

Subject: Finance, Business, Economics And Management Keywords: Auxiliary Innovation; Digital Banking Customers; Digital Risk; Financial Inclusion

Online: 24 April 2024 (05:15:05 CEST)

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In recent years, the digital economy has played an increasingly important role in enhancing productivity, fostering growth, and facilitating the emergence of digital banking. With the widespread adoption of digital financial services for financial inclusion, the banking sector is experiencing a demand for digital transformation. It is important to note that despite the many advantages of this change, it also disrupts the familiar banking experience that customers have grown to expect, as well as introducing potential risks to maintaining customer protection at previous levels. Many critics have raised concerns regarding customer protection and potential exposure to various risks that may arise from digital financial services, which may result in both financial and non-financial losses. These risks can impact customer retention as dissatisfied customers may switch to alternative service providers. Additionally, reputation can be affected since merely offering digital financial services may not sufficiently safeguard customers. To remain competitive, financial institutions must deliver a secure experience that aligns with customer expectations while considering economic factors and societal needs. This is why it is essential to comprehend the severity of the risk factors that influence the protection of customers in the realm of digitalized banking services and products. In this study, five factors have been identified that influence customer protection when using digital financial services in Pakistan. Based on the analysis conducted using SmartPLS, it appears that all the factors proposed in this study have a significant and positive impact on the protection of customers. In particular, the information provided remains of paramount importance when it comes to determining the level of protection that a customer is entitled to within digital financial services, followed by responsiveness, privacy, authentication, and encryption mechanisms. Due to these findings, the implementation of enhanced information security management principles becomes imperative for the development and progress of the Pakistani digital banking industry.

Preprint ARTICLE | doi:10.20944/preprints202404.1557.v1

Exploring Seizure Dynamics: A Computational Model of Epilepsy

Richard Murdoch Montgomery

Subject: Biophysics, Biology And Life Sciences Keywords: Epilepsy Dynamics
Computational Model

Online: 24 April 2024 (05:12:14 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202404.1583.v1

Some Results on Coefﬁcient Estimate Problems for Four-Leaf-Type Bounded Turning Functions

Chuanjun Wen, Zongtao LI, Dong Guo

Subject: Computational Mathematics, Computer Science And Mathematics Keywords: Hankel determinant; Schwarz functions; bounded turning functions; four-leaf-type domain

Online: 24 April 2024 (04:43:56 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202402.1612.v3

Defining the Minimal Long-Term Follow-Up Data Elements for Newborn Screening

Yvonne Kellar-Guenther, Lauren Barringer, Katherine Raboin, Ginger Nichols, Kathy YF Chou, Kathy Nguyen, Amy R. Burke, Sandy Fawbush, Joyal B. Meyer, Morna Dorsey, Amy Brower, Kee Chan, Mei Lietsch, Jennifer Taylor, Michele Caggana, Marci K. Sontag

Subject: Public Health And Health Services, Public Health And Healthcare Keywords: newborn screening; public health; equity; long-term follow-up data

Online: 24 April 2024 (03:49:20 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202404.1564.v1

A Non-parametric Approach-based Trade-off between Food System Efficiency and Robustness

Muna A. Al-Ansari, Hamad Nabeel, Galal M. Abdella, Tarek El Mekkawy, Adeeb A. Kutty

Subject: Other, Engineering Keywords: Data Envelopment Analysis (DEA); Food Systems Robustness; Food Security; Slacks Based Measure (SBM); Analytic Hierarchy Process (AHP)

Online: 24 April 2024 (03:43:17 CEST)

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Balancing the efficiency and robustness of food systems is a well-known trade-off process. Over-optimization of efficiency may lead to excessive use of resources. On the other hand, under-optimization of efficiency may lead to excessive waste of resources. Using non-parametric methods can help in developing actionable frameworks through which decision-makers and stakeholders can effectively balance and improve food systems' efficiency and robustness. Under this context, this paper presents a new structured approach integrating two well-suited non-parametric methods for analyzing and balancing the interconnection between the efficiency and robustness of food systems. This approach consists of three main steps. First, the slacks-based data envelopment analysis (SBM-DEA) is utilized to analyze the efficiency of five food robustness dimensions. Second, the weighted efficiency of these dimensions is computed and analyzed to provide an insight into their influence on the food system efficiency. Finally, two search methods were developed to identify opportunities for improving efficiency and robustness. The outcomes of these methods have been analyzed and validated to ensure their effectiveness and viability. The operational and mathematical properties of the proposed approach were evaluated using data from thirty-seven food-producing countries. The weights of the robustness dimensions in this study were determined using the analytic hierarchy process (AHP) method. The input matrix of the AHP was constructed using expert judgment and consultations with stakeholders. The results of this study have shown an appropriate level of applicability and effectiveness of the proposed approach. While the first search method provided valuable insights, the second method proved to be more effective in identifying the sources of inefficacy of robustness dimensions. Several conclusions have been drawn and reported with some recommendations for future research works.

Preprint ARTICLE | doi:10.20944/preprints202404.1485.v1

Response of Photosynthetic Capacity to Climate Warming and Its Variation among 11 Provenances of Dahurian Larch (Larix gmelinii)

Ping Rui Tian, Yao Lu Li, Jia Dong Zhang, Jun Zhang, Kuan Chuan Wang, Kui Xian Quan

Subject: Forestry, Biology And Life Sciences Keywords: Boreal forest; Climate change; Photosynthetic capacity; Adaptation

Online: 24 April 2024 (03:41:32 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202404.1490.v1

Driving Reality vs Simulator: Data Distinctions

Natalia Piaseczna, Rafał Doniec, Szymon Sieciński, Klaudia Barańska, Marek Jędrychowski, Marcin Grzegorzek

Subject: Bioengineering, Engineering Keywords: electrooculography; driving simulation; real-world driving; data distinctions; biomedical signal processing

Online: 24 April 2024 (03:33:57 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202404.1419.v1

A Nature-Inspired Approach to Energy-Efficient Relay Selection in LPWAN

Anna Strzoda, Krzysztof Grochla

Subject: Computer Science, Computer Science And Mathematics Keywords: LPWAN; LoRaWAN; 2-hop; Relay-Device; Sensor networks; Nature-inspired algorithms; Metaheuristics

Online: 24 April 2024 (03:30:57 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202404.1516.v1

Disturbance Rejection Control of Grid-Forming Inverter for Line Impedance Parameter Perturbation in Weak Power Grid

Mayue Huang, Hui Li

Subject: Electrical And Electronic Engineering, Engineering Keywords: grid-forming inverter; power decoupling; reduced-order extended state observer; dynamic phasor method; virtual impedance; line impedance parameter perturbation

Online: 24 April 2024 (02:59:16 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202404.1521.v1

Key Aroma Differences in Volatile Compounds of Aged Feng-flavored baijiu Determined using Sensory Descriptive Analysis and GC×GC–TOFMS

Jinmei Ren, Zhi jian Li, Wei Jia

Subject: Food Chemistry, Chemistry And Materials Science Keywords: feng-flavored baijiu; sensory descriptive analysis; GC×; GC– TOFMS; chemometrics; key differential compounds

Online: 24 April 2024 (02:48:52 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202404.1529.v1

Historical Overview of the Evolution of Studies and Classifications of Renal Tumors

Rafik BEN TAYEB, Hinde ELFATEMI

Subject: Primary Health Care, Public Health And Healthcare Keywords: kidney carcinoma history;

Online: 23 April 2024 (18:10:17 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202404.1528.v1

Near Field Propagation of Flat-Top Gaussian Beam: Analysis in ‎Weak Atmospheric Turbulence

Hussein Thary Khamees, Hussein Thamir Saloom

Subject: Electrical And Electronic Engineering, Engineering Keywords: Weak turbulence; Flat Topped Gaussian (FTG); Near field analysis; Huygens Fresnel Integral

Online: 23 April 2024 (18:07:41 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202404.1548.v1

Fabrication of Sodium Alginate/Polyethyleneimine/ Polyvinyl Alcohol Multilayer Composite Electrospun Nanofiber Membrane for Cu2+ Removal

Boshi Xie, Ziao Zhang, Yujie Lu, Lijuan Cui, Chao Xu, Weijian Shi, Shuping Wu

Subject: Materials Science And Technology, Chemistry And Materials Science Keywords: Electrospinning; nanofiber membranes; multilayer composite; sodium alginate; polyethyleneimine; copper ion removal

Online: 23 April 2024 (18:06:23 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202404.1547.v1

Does Point of Care Testing Reduce Antibiotic Prescribing in Patients Presenting with Acute Sore Throat to Primary Care? A Prospective Test of Change

Rob Daniels, Esther Miles, Karen Button

Subject: Epidemiology And Infectious Diseases, Medicine And Pharmacology Keywords: Point-of-Care-Testing; GAS infections; molecular; quality improvement; antimicrobial stewardship

Online: 23 April 2024 (18:05:23 CEST)

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Preprint REVIEW | doi:10.20944/preprints202404.1544.v1

Extreme Tolerance of Extraocular Muscles to Diseases and Aging: Why and How?

Angelina Titova, Sergey Nikolaev, Airat Bilyalov, Nikita Filatov, Sergei Brovkin, Dmitrii Shestakov, Igor Khatkov, Ekaterina Pismennaya, Vyacheslav Bondarev, Margarita Antyuxina, Elena Shagimardanova, Natalia Bodunova, Oleg Gusev

Subject: Biology And Biotechnology, Biology And Life Sciences Keywords: extraocular muscles; muscular dystrophies; muscular aging

Online: 23 April 2024 (18:02:07 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202404.1530.v1

The Seismic Performance of Self-Centering Ribbed Floor Flat Beam Frame Joints

Hongyu Chen, Fei Wang, Likun Li, Qixuan Liu, Xiandong Kang

Subject: Civil Engineering, Engineering Keywords: Prestressed friction joint; low frequency cyclic loading; Energy dissipation performance; Hybrid joint; Low damage

Online: 23 April 2024 (18:00:52 CEST)

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To achieve rapid post-earthquake repair of self-centering ribbed floor flat beam frame structures, a ductile hybrid joint consisting of dog bone weakened energy dissipating steel bars connected to the upper and lower column sections through high-strength threads based on the damage control design concept is proposed. By moving the ductile energy dissipating zone out to the locally weakened section of the energy dissipating steel bars and the locally unbonded prestressed steel bars in the core area, the residual deformation was limited and the seismic performance was improved. Based on the working principle of hybrid joints, low cycle loading tests were conducted on two joint specimens to analyze the influence of lateral prestress on the seismic performance of the hybrid joints. Numerical modeling methods were used to compare the position of the energy-consuming steel bars in the composite layer and the friction performance of joints. The research results indicated that the hybrid joint had stable load-bearing, deformation, and energy dissipation capabilities, with damage primarily concentrated on the energy-consuming steel bars. Even at an inter-story displacement angle of 5.5%, the upper and lower column segments remained elastic. After unloading, the connection seam at the joint was closed, and the self-centering performance was good. When the inter-story displacement angle reached 5.5%, the lateral prestress increased from 150 kN to 250 kN, the ultimate bearing capacity of the joint increased by 16.3%, and the cumulative energy consumption increased by 30.0%. The influence of the friction coefficient of the joint surface on the structural performance was set at a threshold of 0.7. When it was less than the threshold, the ultimate bearing capacity and initial stiffness of the joint increased with an increase in the friction coefficient. After reaching the threshold, the increase in the ultimate bearing capacity of the joint slowed down, and the rate of stiffness degradation gradually accelerated. This joint had excellent seismic performance and can also achieve post-earthquake repair of structures.

Preprint ARTICLE | doi:10.20944/preprints202404.1531.v1

An Evaluation of the Primary Causative Factors Affecting Durability of Flow Diversion Simple Weirs in Muchinga Province in Zambia

Alex Lushikanda KABWE, Masahiro HYODO, Hidehiko OGATA, Yoshihiro Sagawa, Yoshinao ADACHI, Masayuki ISHII

Subject: Other, Engineering Keywords: farmer-led small-scale irrigation; operation and maintenance; catchment characteristics; durability assessment; local material; farmer perception

Online: 23 April 2024 (17:59:45 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202404.1536.v1

The Effectiveness of Nutritional Interventions Implemented Through Lady Health Workers on the Reduction of Stunting in Children under 5 in Pakistan; The Difference‐in‐Difference Analysis

Khizar Ashraf, Tanvir M. Huda, Javeria Ikram, Shabina Ariff, Muhammad Sajid, Gul Nawaz Khan, Muhammad Umer, Imran Ahmed, Michael John Dibley, Sajid Bashir Soofi

Subject: Public Health And Health Services, Public Health And Healthcare Keywords: nutrition; Pakistan; Stunting prevention; Lipid based nutrient supplements; programmatic review

Online: 23 April 2024 (17:51:57 CEST)

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Preprint REVIEW | doi:10.20944/preprints202402.0799.v2

Platelet Biorheology and Mechanobiology in Thrombosis and Hemostasis: Perspectives from Multiscale Computation

Rukiye Tuna, Wenjuan Yi, Esmeralda Crespo Cruz, JP Romero, Yi Ren, Jingjiao Guan, Yan Li, Yuefan Deng, Danny Bluestein, Z. Leonardo Liu, Jawaad Sheriff

Subject: Bioengineering, Engineering Keywords: von Willebrand factor; platelet margination; platelet adhesion; shear-induced platelet aggregation; platelet mechanobiology; biorheology; platelet activation; thrombosis

Online: 23 April 2024 (17:50:04 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202404.1523.v1

Accurate Calculation of Upper Biomass Volume of Single Trees Using Matrixial Representation of LiDAR Data

Fayez Tarsha Kurdi, Elżbieta Lewandowicz, Zahra Gharineiat, Jie Shan

Subject: Remote Sensing, Environmental And Earth Sciences Keywords: LiDAR; tree modeling; upper biomass; tree crown; tree trunk; point cloud

Online: 23 April 2024 (17:23:23 CEST)

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Preprint REVIEW | doi:10.20944/preprints202404.1532.v1

Therapeutic Effects of Plant Anthocyanin Against Alzheimer’s Disease and Modulate Gut Health, Short-Chain Fatty Acids

Al Borhan Bayazid, Beong Ou Lim

Subject: Neuroscience And Neurology, Biology And Life Sciences Keywords: Anthocyanins; Plant Bioactive; Cognition; Neuroprotection; SCFAs; Aβ and Tau

Online: 23 April 2024 (17:21:01 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202404.1522.v1

Heat and Mass Transformation of Casson Hybrid Nano Fluid (MoS2 + ZnO) based on Engine Oil over a Stretched Wall with Chemical Reaction and Thermo-diffusion Effect

Shreedevi Madiwal, Neminath B. Naduvinamani

Subject: Mechanical Engineering, Engineering Keywords: Casson Hybrid nanofluid; Engine oil; Heat and Mass Transformation; Magnetic field; Soret effect; Chemical reaction

Online: 23 April 2024 (17:19:33 CEST)

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This study investigates the potential of a hybrid nanofluid composed of MoS2 and ZnO nanoparticles dispersed in engine oil, aiming to enhance the properties of lubricant's chemical reaction with the Soret effect on stretching sheet under the influence of applied magnetic field. With the growing demand for efficient lubrication systems in various industrial applications, including automotive engines, the development of novel nanofluid-based lubricants presents a promising avenue for improving engine performance and longevity. However, the synergistic effects of hybrid nanoparticles in engine oil remain relatively unexplored. This research addresses this gap by examining the thermal conductivity, viscosity, and wear resistance of the hybrid nanofluid, shedding light on its potential as an advanced lubrication solution. By analyzing the dispersion stability and interaction mechanisms between nanoparticles and base oil, valuable insights are gained into the fundamental aspects governing the entertainment of hybrid nano lubricants. Overall, the objectives of studying hybrid nano lubricant MoS2+ZnO with engine oil aim to advance the development of more efficient and durable lubrication solutions for automotive engines, contributing to improved reliability, fuel efficiency, and environmental sustainability. Governing non-linear partial differential equations are simplified as ordinary differential equations by utilizing similarity variables. MATLAB Bvp4c technique is used to solve the obtained linear ODE equations. The outputs are presented through graphs and tables for various state variables. The comparative survey in all the graphs is presented for the nanofluid (MoS2/Engine oil) with the hybrid nanofluid (MoS2+ZnO/Engine oil). These graphs show the effect of various parameters M, Q, β, Pr, Ec, Sc, Sr, Kp, Kr and (hybrid nano lubricant parameter). The velocity profile diminished against the values of M, Kp, and β. Temperature profile rising with Ec and Q. reciprocally goes down to Pr. The concentration profile incremented with the value of Sr and decremented with the value of Sc, and Kr. With the increasing value of both f′ (η) and θ(η) increases. But in θ(η) hybrid nanofluid slows down with the higher value of .

Preprint ARTICLE | doi:10.20944/preprints202404.1534.v1

THz Wave Power Enhancement Using a Microstrip Line-based Combiner Integrated with Arrayed UTC-PDs

Hussein Ssali, Yoshiki Kamiura, Ryo Doi, Hiroki Agemori, Ming Che, Yuya Mikami, Kazutoshi Kato

Subject: Electrical And Electronic Engineering, Engineering Keywords: Microstrip line; patch antenna; terahertz wave; uni-travelling carrier photodiode; Wilkinson power combiner

Online: 23 April 2024 (17:18:27 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202404.1283.v2

Sustainable Geoinformatic Approaches to Insurance for Small-Scale Farmers in Colombia

Ahmad Abd Rabuh, Richard M. Teeuw, Doyle Ray Oakey, Athanasios V. Argyriou, Max Foxley-Marrable, Alan Wilkins

Subject: Sustainable Science And Technology, Environmental And Earth Sciences Keywords: deep learning; digital data poverty; disaster risk management; earth observation; extreme weather; GIS; machine learning; parametric insurance; small farms; sustainable geoinformatics.

Online: 23 April 2024 (17:17:18 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202404.1527.v1

TLR Agonists Modify NK Cell Activation and Increase Its Cytotoxicity in Acute Lymphoblastic Leukemia

Janet Gallardo-Zapata, Erandi Pérez-Figueroa, Víctor Olivar-López, Aurora Medina-Sanson, Elva Jiménez-Hernández, Enrique Ortega, Carmen Maldonado-Bernal

Subject: Other, Biology And Life Sciences Keywords: Natural-killer-cells; Toll-like receptors; cytotoxicity; acute lymphoblastic leukemia; IFN-γ ; NKG2D; NKp44 7

Online: 23 April 2024 (17:15:36 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202404.1541.v1

Human Papillomavirus Vaccination Status among Fertility Patients

Miriam Tarrash, Emma Brenner, Stephanie R. Brownridge, Arisa Kapedani, Randi H. Goldman, Gary L. Goldberg, Christine Mullin

Subject: Primary Health Care, Public Health And Healthcare Keywords: Human papillomavirus (HPV); vaccination; infertility

Online: 23 April 2024 (17:14:19 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202404.1520.v1

Design and Synthesis of Multifunctional Symmerical Squaraine Dyes for Molecular Photovoltaics by Terminal Alkyl-Chain Modifications

Kota Mori, Yuki Kurokawa, SHYAM S. PANDEY

Subject: Applied Chemistry, Chemistry And Materials Science Keywords: Dye-sensitized solar cells; Squaraine dye; Electrolyte effect; Terminal modification; Multifunctional; Dye sensitizer

Online: 23 April 2024 (17:13:13 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202404.1550.v1

Non-syndromic and Syndromic Defects in Children with Extracranial Germ Cell Tumors (eGCT): Data of 2,610 Children Registered with the German MAKEI 96/MAHO 98 Registry Compared to the General Population

Judit Schultewolter, Anke K. Rißmann, Dietrich Von Schweinitz, Michael Frühwald, Claudia Blattmann, Lars Fischer, Bjoern Soenke Lange, Rüdiger Wessalowski, Birgit Fröhlich, Wolfgang Behnisch, Irene Schmid, Harald Reinhard, Matthias Duerken, Patrick Hundsdoerfer, Martin Heimbrodt, Christian Vokuhl, Stefan Schönberger, Dominik T. Schneider, Guido Seitz, Ulrich Göbel, Rüdiger Von Kries, Heiko M. Reutter, Gabriele Calaminus

Subject: Pediatrics, Perinatology And Child Health, Medicine And Pharmacology Keywords: germ cell tumor; syndrome; non-syndromic defect

Online: 23 April 2024 (16:59:48 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202404.1546.v1

Experimental Evaluation of Mechanical Compression Properties of Aluminum Alloy Lattice Trusses for Anti-ice System Applications

Carlo Giovanni Ferro, Sara Varetti, Paolo Maggiore

Subject: Aerospace Engineering, Engineering Keywords: Additive Manufacturing (AM); Selective Laser Sintering (SLM); Lattice Structures; Design of Experiments (DOE)

Online: 23 April 2024 (16:58:27 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202404.1549.v1

Clinical Outcome of Patients with Escherichia coli Isolated from Catheter Lumens and/or Peripheral Blood Cultures: A Retrospective Analysis

Álvaro Irigoyen-von-Sierakowsi, Marta Díaz-Navarro, Andrés Visedo, María Jesús Pérez-Granda, Pablo Martín-Rabadán, Patricia Munoz, María Guembe

Subject: Epidemiology And Infectious Diseases, Medicine And Pharmacology Keywords: Escherichia coli; bacteremia; catheter; lock therapy; differential time to positivity; biofilm; outcome.

Online: 23 April 2024 (16:57:14 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202404.1545.v1

Effect of a National Health Insurance Coverage Benefit Extension Policy on Long-Term Outcomes of Ventilated Patients with Severe Pneumonia: A Nationwide Cohort Study

Wanho Yoo, Hyojin Jang, Min Ki Lee, Hye-Kyung Park, Mi-Hyun Kim, Yeongdae Kim, Jungmin Son, Jinmi Kim, Kwangha Lee

Subject: Pulmonary And Respiratory Medicine, Medicine And Pharmacology Keywords: health expenditures; health insurance; Pneumonia; mechanical ventilator; mortality

Online: 23 April 2024 (15:28:03 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202404.1539.v1

Effects of Substrate Composition on the Growth Traits of Grafting Seedling in Macadamia Nuts

Qiu Jin Tan, Chun Heng Zhou, Peng Xu, Xi Yuan Huang, Yuan Rong Wei, Zhen Zhen Pan, Wen Lin Wang, Li feng Wang

Subject: Agricultural Science And Agronomy, Biology And Life Sciences Keywords: Macadamia nuts; substrate; surviving rate; growth; grafted seedling

Online: 23 April 2024 (14:56:46 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202404.1537.v1

In Situ Gelling Behavior and Biopharmaceutical Characterization of Nono-Silver Loaded Poloxamer Matrices Designed for Nasal Drug Delivery

Nadezhda Ivanova, Neli Ermenlieva, Lora Simeonova, Neli Vilhelmova-Ilieva, Kameliya Bratoeva, Georgi Stoyanov, Velichka Andonova

Subject: Nanotechnology, Chemistry And Materials Science Keywords: silver nanoparticles; chlorhexidine; Kolliphor P407; thermogelation; phase transition; sol-gel transition; protective nasal spray; respiratory infections; prophylaxis; virucidal activity

Online: 23 April 2024 (14:52:13 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202404.1540.v1

Simple Histogram Equalization Technique Improves Performance of VGG models on Facial Emotion Recognition Datasets

Jaher Hassan Chowdhury, Qian Liu, Sheela Ramanna

Subject: Artificial Intelligence And Machine Learning, Computer Science And Mathematics Keywords: Facial emotion recognition; Convolutional Neural Network; Histogram Equalization; Transfer Learning; VGG architecture

Online: 23 April 2024 (14:50:40 CEST)

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Preprint REVIEW | doi:10.20944/preprints202404.1538.v1

Is the Myasthenia Gravis (MG) the Result of Age and Sex/Gender? A Narrative Review for Identifying Genetic and Epigenetic Biomarkers for a Differential MG Management in Old and Young Women

Carmela Rita Balistreri

Subject: Neuroscience And Neurology, Medicine And Pharmacology Keywords: Myasthenia gravis (MG); age and sex/gender; two different forms; genetic and epigenetic factors

Online: 23 April 2024 (14:48:58 CEST)

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