ARTICLE
|
doi:10.20944/preprints202304.1063.v1
Subject:
Medicine And Pharmacology,
Urology And Nephrology
Keywords:
empagliflozin; vascular calcification; AMP-activated protein kinase; nuclear factor erythroid-2-related factor; heme oxygenase 1; chronic kidney disease
Online: 27 April 2023 (09:35:25 CEST)
REVIEW
|
doi:10.20944/preprints202107.0353.v1
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
Lung cancer; Adjuvant treatment; Non-small-cell lung carcinoma (NSCLC); Epidermal growth factor receptor (EGFR); Tyrosine kinase inhibitor (TKI)
Online: 15 July 2021 (10:16:30 CEST)
ARTICLE
|
doi:10.20944/preprints202105.0638.v1
Subject:
Medicine And Pharmacology,
Immunology And Allergy
Keywords:
18F-FDG PET/CT; contrast-enhanced CT; melanoma; metastases; tyrosine kinase inhibitors; Immune checkpoint inhibitors; follow-up; therapy monitoring
Online: 26 May 2021 (13:14:06 CEST)
COMMUNICATION
|
doi:10.20944/preprints202104.0275.v1
Subject:
Biology And Life Sciences,
Anatomy And Physiology
Keywords:
fludioxonil; fungicide; mode of action; high osmolarity glycerol (HOG) pathway; Magnaporthe oryzae; signal transduction; histidine kinase; MoHIK1; HIK1; phenylpyrrole
Online: 12 April 2021 (09:38:33 CEST)
ARTICLE
Subject:
Medicine And Pharmacology,
Immunology And Allergy
Keywords:
18F-FDG PET/CT; contrast-enhanced CT; melanoma; metastases; tyrosine kinase inhibitors; Immune checkpoint inhibitors; follow-up; therapy monitoring
Online: 25 January 2021 (15:01:17 CET)
ARTICLE
|
doi:10.20944/preprints202012.0582.v1
Subject:
Medicine And Pharmacology,
Immunology And Allergy
Keywords:
Liquid-based 3D culture; tumoroid; cisplatin resistance; imatinib (gleevec); tyrosine kinase inhibitor (TKI); organoid; spheroid; metastatic colorectal cancer (mCRC)
Online: 23 December 2020 (10:15:46 CET)
ARTICLE
|
doi:10.20944/preprints202306.0068.v1
Subject:
Medicine And Pharmacology,
Other
Keywords:
3D printed scaffolds; carbon nanotube; capped carbon nanotube; protein kinase A; pseudomonas elastase; exotoxin A; alpha-hemolysin; shiga toxin 2a
Online: 5 June 2023 (02:56:10 CEST)
REVIEW
|
doi:10.20944/preprints202112.0282.v1
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
Acalabrutinib; Bruton’s tyrosine kinase; BTK; CLL; Covalent inhibitors; COVID-19; Ibrutinib; Non-covalent inhibitors; Fenebrutinib; MK1026; Pirtobrutinib; Spebrutinib; Tirabrutinib; Zanubrutinib
Online: 16 December 2021 (16:13:54 CET)
ARTICLE
|
doi:10.20944/preprints201911.0399.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
olivo-ponto-cerebellar atrophy (OPCA); Purkinje cells; Calcium/calmodulin dependent protein kinase II (CAMK2); Plastin (Fimbrin); Hirano bodies; Huntington’s disease
Online: 30 November 2019 (14:47:30 CET)
REVIEW
|
doi:10.20944/preprints202312.1057.v1
Subject:
Biology And Life Sciences,
Toxicology
Keywords:
cardiotonic steroids; endogenous cardiotonic steroids; ouabain; blood; blood cells; red blood cells; Na,K-ATPase; Src-kinase; signalling cascades; immunogenic effects
Online: 14 December 2023 (06:14:30 CET)
REVIEW
|
doi:10.20944/preprints202309.1651.v1
Subject:
Biology And Life Sciences,
Endocrinology And Metabolism
Keywords:
cyclic AMP; cyclic PIP; insulin resistance; prostaglandylinositol cyclic phosphate; protein phosphorylation; protein kinase A; protein ser/thr phosphatase; type 2 diabetes
Online: 25 September 2023 (11:05:29 CEST)
ARTICLE
|
doi:10.20944/preprints202308.0382.v1
Subject:
Medicine And Pharmacology,
Pathology And Pathobiology
Keywords:
pleural mesothelioma; subtypes; immunohistochemistry; Mesothelin; Claudin-15; Complement Factor B (CFB); Plasminogen Activator Inhibitor 1 (PAI1); p21-activated kinase 4 (PAK4).
Online: 4 August 2023 (12:34:31 CEST)
REVIEW
|
doi:10.20944/preprints201903.0138.v1
Subject:
Biology And Life Sciences,
Cell And Developmental Biology
Keywords:
extracellular signal-regulated kinase; MAPK/ERK signaling; intracellular signaling; kidney development; ureteric bud branching morphogenesis; nephrogenesis; progenitor cells; self-renewal; differentiation
Online: 13 March 2019 (09:00:32 CET)
REVIEW
|
doi:10.20944/preprints201807.0237.v1
Subject:
Medicine And Pharmacology,
Immunology And Allergy
Keywords:
TRPM7, kinase, inflammation, lymphocytes, calcium signalling, SMAD, TH17, hypersensitivity, regulatory T cells, thrombosis, graft versus host disease, T cells, innate immunity
Online: 13 July 2018 (14:14:56 CEST)
REVIEW
|
doi:10.20944/preprints202305.0606.v1
Subject:
Medicine And Pharmacology,
Anatomy And Physiology
Keywords:
alcoholic fatty liver; adenosine monophosphate activated kinase; sterol regulatory element binding protein 1c; peroxisome proliferator activated receptor , oxidative stress; cytochrome P450 2E1
Online: 9 May 2023 (08:38:13 CEST)
ARTICLE
|
doi:10.20944/preprints202009.0374.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
aldosterone; apoptosis; cardiac myocyte; eplerenone; fibrosis; finerenone; G protein-coupled receptor kinase (GRK)-5; mineralocorticoid receptor; mineralocorticoid receptor antagonist (MRA); signal transduction
Online: 17 September 2020 (05:24:29 CEST)
REVIEW
Subject:
Medicine And Pharmacology,
Neuroscience And Neurology
Keywords:
Parkinson’s disease; precision medicine; personalized medicine; GBA; Glucocerebrosidase; GCase; LRRK2; Leucine-rich repeat kinase-2; Dopamine; PD drug trials; PD risk variants
Online: 14 September 2020 (00:22:59 CEST)
ARTICLE
|
doi:10.20944/preprints201911.0061.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
rett syndrome; intrinsically disordered region; phylogenetic profile analysis; post-transcriptional modification; methyl-cpg-binding protein 2; cyclin-dependent kinase-like 5; forkhead box protein g1
Online: 6 November 2019 (10:58:54 CET)
ARTICLE
|
doi:10.20944/preprints201907.0013.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
Rett Syndrome; intrinsically disordered region; phylogenetic profile analysis; post-transcriptional modification; methyl-CpG-binding protein 2; cyclin-dependent kinase-like 5; forkhead box protein G1
Online: 1 July 2019 (11:59:56 CEST)
REVIEW
|
doi:10.20944/preprints201811.0389.v1
Subject:
Medicine And Pharmacology,
Cardiac And Cardiovascular Systems
Keywords:
adverse remodeling; aldosterone; cardiac myocyte; crosstalk; G protein-coupled receptor (GPCR); GPCR-kinase (GRK); heart failure; inflammation; mineralocorticoid receptor; myocardial infarction; oxidative stress; signal transduction
Online: 16 November 2018 (07:54:04 CET)
ARTICLE
|
doi:10.20944/preprints202212.0542.v2
Subject:
Medicine And Pharmacology,
Oncology And Oncogenics
Keywords:
safety analysis; targeted therapy; monoclonal antibody therapy; immune checkpoint inhibibitors; tyrosine kinase inhibitors; breast cancer; gynecological cancer; Helixor; Viscum album L.; PARP inhibitors; CDK 4/6 inhibitors
Online: 30 December 2022 (12:00:35 CET)
REVIEW
|
doi:10.20944/preprints202309.1260.v1
Subject:
Medicine And Pharmacology,
Pediatrics, Perinatology And Child Health
Keywords:
PANDAS; Pediatric Autoimmune Neuropsychiatric Disorders Associated with Streptococcal Infections; PANDAS syndrome; neuropsychiatric disorder; streptococci; molecular mimicry; CaM kinase; striatal cholinergic interneurons; obsessive-compulsive disorder; streptococcal infection; tic; tics
Online: 19 September 2023 (07:09:19 CEST)
REVIEW
|
doi:10.20944/preprints202309.1526.v1
Subject:
Biology And Life Sciences,
Neuroscience And Neurology
Keywords:
neurodegeneration with brain iron accumulation (NBIA); pantothenate kinaseassociated neurodegeneration (PKAN); pantothenate kinase 2 (PANK2); pantothenate; pantethine; vitamin E; omega 3; -lipoic acid; L-carnitine; thiamine; fibroblasts; induced neurons; precision medicine
Online: 22 September 2023 (09:18:39 CEST)
ARTICLE
|
doi:10.20944/preprints202305.0339.v1
Subject:
Biology And Life Sciences,
Plant Sciences
Keywords:
Banana; fine mapping; quantitative trait locus; Musa acuminata ssp. malaccensis; Fusarium wilt; Fusarium oxysporum f. sp. cubense; Tropical Race 4; Subtropical Race 4; marker assisted selection; resistance gene expression; receptor-like kinase; RNAseq
Online: 5 May 2023 (09:51:49 CEST)
ARTICLE
|
doi:10.20944/preprints202203.0290.v2
Subject:
Biology And Life Sciences,
Biology And Biotechnology
Keywords:
host-virus interactions; tissue-specific model; COVID-19; SARS-CoV-2; antiviral targets; flux balance analysis; flux variability analysis; reaction knockout; host-derived enforcement; metabolic modeling; virus mutations; nucleoside diphosphate kinase; software engineering; Python
Online: 27 July 2022 (10:37:12 CEST)
ARTICLE
|
doi:10.20944/preprints201707.0033.v1
Subject:
Medicine And Pharmacology,
Gastroenterology And Hepatology
Keywords:
hepatic inflammation; high-fat-cholesterol diet; hypertension; mitogen-activated protein kinase; nonalcoholic steatohepatitis; nuclear factor erythroid 2-related factor 2 pathway; nuclear factor-kappa B; spontaneously hypertensive rat; stroke-prone spontaneously hypertensive5/Dmcr; Wistar Kyoto
Online: 14 July 2017 (10:54:38 CEST)