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Preprint REVIEW | doi:10.20944/preprints202308.0766.v1

Diagnosis Progress and Treatment Update of Kawasaki Disease

Ho-Chang Kuo

Subject: Medicine And Pharmacology, Pediatrics, Perinatology And Child Health Keywords: Kawasaki disease; diagnosis; biomarkers; treatment; eosinophil

Online: 10 August 2023 (05:08:14 CEST)

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Preprint ARTICLE | doi:10.20944/preprints201902.0187.v1

Clinical Characteristics for Differentiating Febrile Children with Suspected Kawasaki Disease Diagnosis

Jia-Huei Yan, Ling-Sai Chang, Yi-Ju Lin, Mindy Ming-Huey Guo, Ying-Hsien Huang, Ho-Chang Kuo

Subject: Medicine And Pharmacology, Pediatrics, Perinatology And Child Health Keywords: clinical characteristics; febrile children; Kawasaki disease

Online: 20 February 2019 (09:10:15 CET)

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Preprint CASE REPORT | doi:10.20944/preprints202304.0453.v1

An Infant Case of Coronary Artery Aneurysms with No Systemic Symptoms after Treatment for Kawasaki Disease

Yumiko Asai, Takanori Suzuki, Midori Yamada

Subject: Medicine And Pharmacology, Pediatrics, Perinatology And Child Health Keywords: Coronary artery abnormalities; Infants; Kawasaki disease

Online: 17 April 2023 (10:45:30 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202401.0857.v1

Etiology Model of Kawasaki Disease and Multisystem Inflammatory Syndromes

Darrell O. Ricke, Nora Smith

Subject: Biology And Life Sciences, Life Sciences Keywords: Kawasaki disease; multisystem inflammatory syndrome; Henoch-Schönlein purpura; MIS-C; MIS-A; MIS-N; MIS-V; Kawasaki Disease Shock Syndrome; vaccines

Online: 11 January 2024 (11:28:02 CET)

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Preprint BRIEF REPORT | doi:10.20944/preprints202211.0436.v1

Multiplex PCR Detects Respiratory Viruses at A Much Higher Rate in Kawasaki Disease

Masayuki Nagasawa, Teruyoshi Shimoyama, Sayuri Hashimoto, Ryuichi Nakagawa, Haruna Yokoyama, Mari Okada, Tomohiro Udagawa, Akihiro Oshiba

Subject: Medicine And Pharmacology, Pediatrics, Perinatology And Child Health Keywords: Kawasaki disease; febrile convulsions; respiratory virus; filmarray; multiplex PCR

Online: 23 November 2022 (07:02:54 CET)

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Preprint REVIEW | doi:10.20944/preprints202005.0160.v1

COVID-19 and Kawasaki Like Disease: The Known-Known, the Unknown-Known and the Unknown-Unknown

Aurélie Morand, Diego Urbina, Alexandre Fabre

Subject: Medicine And Pharmacology, Pediatrics, Perinatology And Child Health Keywords: Sars-Cov2; Covid-19; Children; Kawasaki disease; toxic shock syndrome

Online: 9 May 2020 (09:01:24 CEST)

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In the end of April nearly 100 cases of children aged between 6 month and 9 years with Kawasaki like disease were reported (mostly in Europe) probably linked to COVID-19. With the increasing awareness of this condition the number of cases reported is increasing worldwide. We aim to sum up the known data about this new entity based on published data (in a case report, a series of 8 cases and in newspapers and society statement) and using our knowledge of classical Kawasaki disease. It seems to be a post infectious disease with an onset between 2-4 weeks after the infection, probably in genetically predisposed children aged between 6 month to 17 years. A very rough estimation of incidence based on current data from Bergamo, Italy, and New York State and a lot assumption is between 0.016% (95% CI:0.013-0.02%) - 0.31% (95% CI: 0.2-0.47%) of infected children. Clinical signs overlaps with Kawasaki disease in some children, but another feature is prominent gastrointestinal manifestations. For the 9 detailed patients most had incomplete presentation for Kawasaki disease (with a mean 1.7 (+/-1.2) criteria per patient for the 5 non fever criterion) and only one had a classical form. In some cases, presentation is closer to toxic shock syndrome or isolated myocarditis. Persistent fever seems to be constant and biological exploration are consistent with inflammation (elevated CRP, ferritin and D-Dimers). Management is described as supportive and children seem to improve rapidly, but can require cardiac or respiratory support. In date of 11 may 2020 there is 4 deaths confirmed linked to these new entities (1 in UK and 3 in New York). Paediatricians and general practitioners need to be aware of these possible evolution following COVID-19 infection. However it seems to be rare and children are probably still spared from most morbidities and mortality linked to COVID-19 infection .There are need of published detailed cohorts to better delineate these entities.

Preprint REVIEW | doi:10.20944/preprints202309.1883.v1

Role of Neutrophil Extracellular Traps in Health and Disease Pathophysiology: Recent Advancements and Future Insights

Md. Monirul Islam, Naoshi Takeyama

Subject: Medicine And Pharmacology, Immunology And Allergy Keywords: neutrophil extracellular traps (NETs); innate immunity; sepsis; lung disease; cardiovascular disease; liver disease; kidney disease; diabetes; COVID-19; coagulopathy and thrombotic microangiopathy; cancer; autoimmunity; preeclampsia; Kawasaki disease

Online: 28 September 2023 (04:00:59 CEST)

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Preprint ARTICLE | doi:10.20944/preprints202009.0435.v1

Pediatric Inflammatory Multisystem Syndrome (PIMS) Did Occur in Poland during Months with Low COVID-19 Prevalence. Preliminary Results of a Nationwide Register.

Magdalena Okarska-Napierała, Kamila Ludwikowska, Leszek Szenborn, Natalia Dudek, Anna Mania, Piotr Buda, Janusz Książyk, Katarzyna Mazur-Malewska, Magdalena Figlerowicz, Maciej Szczukocki, Beata Kucińska, Bożena Werner, Lidia Stopyra, Agnieszka Czech, Elżbieta Berdej-Szczot, Aneta Gawlik, Paulina Opalińska, Artur Mazur, Danuta Januszkiewicz-Lewandowska, Cezary Niszczota, Teresa Jackowska, Jacek Wysocki, Paweł Tracewski, Jacek Kusa, Paulina Potocka, Artur Sulik, Katarzyna Ziora, Helena Krakowczyk, Aleksandra Wodniak, Janusz Zaryczański, Alicja Żakiewicz-Cepak, Elżbieta Jarocka-Cyrta, Agnieszka Koczwara, Anna Prusek-Dudkiewicz, Ewa Zbucka-Jachowska, Sabina Langer-Wójcik, Elżbieta Kołodziej, Ernest Kuchar

Subject: Medicine And Pharmacology, Pediatrics, Perinatology And Child Health Keywords: PIMS; MIS-C; SARS-CoV-2; COVID-19; Kawasaki disease; survey

Online: 18 September 2020 (11:29:49 CEST)

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