Preprint Review Version 1 Preserved in Portico This version is not peer-reviewed

Diagnosis Progress and Treatment Update of Kawasaki Disease

Version 1 : Received: 8 August 2023 / Approved: 9 August 2023 / Online: 10 August 2023 (05:08:14 CEST)

A peer-reviewed article of this Preprint also exists.

Kuo, H.-C. Diagnosis, Progress, and Treatment Update of Kawasaki Disease. Int. J. Mol. Sci. 2023, 24, 13948. Kuo, H.-C. Diagnosis, Progress, and Treatment Update of Kawasaki Disease. Int. J. Mol. Sci. 2023, 24, 13948.

Abstract

Since first described by Dr. Tomisaku Kawasaki in 1967, the clinical diagnosis of Kawasaki disease (KD) has remained relatively unchanged. However, studies since then have suggested that diagnoses using only that original clinical criteria may lead to underdiagnosis. In this review, updated KD diagnostic methods, diagnostic methods for “atypical” KD, diagnostic pitfalls, and other differential diagnoses are discussed. Peripheral blood eosinophil showed important in distinguishing KD from febrile children. We review herein the current literature regarding new biomarkers, scoring systems, and microRNA panels that may aid in the diagnosis of KD, the importance of eosinophil and treatment updates.

Keywords

Kawasaki disease; diagnosis; biomarkers; treatment; eosinophil

Subject

Medicine and Pharmacology, Pediatrics, Perinatology and Child Health

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