Preprint Article Version 1 This version is not peer-reviewed

Clinical Characteristics for Differentiating Febrile Children with Suspected Kawasaki Disease Diagnosis

Version 1 : Received: 19 February 2019 / Approved: 20 February 2019 / Online: 20 February 2019 (09:10:15 CET)

How to cite: Yan, J.; Chang, L.; Lin, Y.; Guo, M.M.; Huang, Y.; Kuo, H. Clinical Characteristics for Differentiating Febrile Children with Suspected Kawasaki Disease Diagnosis. Preprints 2019, 2019020187 (doi: 10.20944/preprints201902.0187.v1). Yan, J.; Chang, L.; Lin, Y.; Guo, M.M.; Huang, Y.; Kuo, H. Clinical Characteristics for Differentiating Febrile Children with Suspected Kawasaki Disease Diagnosis. Preprints 2019, 2019020187 (doi: 10.20944/preprints201902.0187.v1).

Abstract

Background: Kawasaki disease (KD) is a form of vasculitis that primarily affects children under the age of 5 years old. Patients may be missed diagnosis when initial clinical symptoms do not fulfill the traditional criteria. We aimed to analyze factors that clinicians could use to differentiate febrile children suspected of KD. Method: We retrospectively enrolled a total of 83 febrile children who were initially suspected of KD, but they did not meet the American Heart Association (AHA) criteria for a diagnosis. However, some of these patients were diagnosed with KD during their second visit. We analyzed patients' characteristics, clinical symptoms, and laboratory data. Results: In total, 50 patients were enrolled in the study. Of those, ten patients were diagnosed with KD on their second visit (group 1), while the other 40 patients still did not fit a KD diagnosis (group 2). A patient with a neutrophil to lymphocyte ratio greater than 1.33 combined with a C-reactive protein more than 33 mg/L was more likely to have KD. Conclusion: Among patients suspected of KD that did not initially meet the criteria, clinicians should pay special attention to elevated neutrophil-to-lymphocyte ratios and CRP levels and closely follow up such patients.

Subject Areas

clinical characteristics; febrile children; Kawasaki disease

Comments (0)

We encourage comments and feedback from a broad range of readers. See criteria for comments and our diversity statement.

Leave a public comment
Send a private comment to the author(s)
Views 0
Downloads 0
Comments 0
Metrics 0


×
Alerts
Notify me about updates to this article or when a peer-reviewed version is published.