HYPOTHESIS
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doi:10.20944/preprints202109.0437.v2
Subject:
Biology And Life Sciences,
Aging
Keywords:
Alzheimer's; Cellular senescence; Neurodegeneration; Microglia; Astrocytes; Oligodendrocyte Progenitor Cells; TREM2; Braak staging; Oxidative stress; Phapoptosis; Amyloid-beta; Tau; Neuritic plaques
Online: 7 March 2022 (14:22:25 CET)
ARTICLE
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doi:10.20944/preprints202404.0469.v1
Subject:
Biology And Life Sciences,
Biophysics
Keywords:
Alzheimer’ s disease; amyloid β peptide; human serum albumin; low-molecular-weight ligand; protein-ligand interaction; surface plasmon resonance spectroscopy
Online: 7 April 2024 (10:18:10 CEST)
REVIEW
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doi:10.20944/preprints202110.0222.v1
Subject:
Medicine And Pharmacology,
Pharmacology And Toxicology
Keywords:
Alzheimer's disease; amyloid-beta; animal model; astrocyte; blood-brain barrier; imaging; metabolism; microglia; neuroinflammation, neurotransmitter receptors; positron emission tomography; synaptic density
Online: 15 October 2021 (11:02:57 CEST)
REVIEW
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doi:10.20944/preprints201802.0047.v1
Subject:
Biology And Life Sciences,
Biochemistry And Molecular Biology
Keywords:
Alzheimer disease; Amyloid β-protein; Antibodies; Cross-reactions; Nucleotide aptamers; Oligonucleotide ligands; Systematic evolution of ligands by exponential enrichment; Specificity; Therapeutics
Online: 5 February 2018 (22:37:02 CET)
ARTICLE
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doi:10.20944/preprints202311.0480.v1
Subject:
Medicine And Pharmacology,
Medicine And Pharmacology
Keywords:
Alzheimer's disease (AD); 4-amino-2,3-polymethylenequinolines; butylated hydroxytoluene (BHT); acetylcholinesterase (AChE); butyrylcholinesterase (BChE); antioxidants; ADMET; β-amyloid; molecular docking; quantum-chemical calculations
Online: 7 November 2023 (15:47:06 CET)
ARTICLE
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doi:10.20944/preprints202405.1741.v1
Subject:
Neuroscience And Neurology,
Medicine And Pharmacology
Keywords:
Alzheimer’ s disease; vascular complications; monoclonal antibody therapy; Aducanumab; Lecanemab; epoxide of polyunsaturated fatty acid; soluble epoxide hydrolase inhibitor EC5026; EP4 inhibitor; monocyte/macrophage; amyloid-beta degradation
Online: 27 May 2024 (13:00:54 CEST)
REVIEW
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doi:10.20944/preprints201903.0108.v1
Subject:
Biology And Life Sciences,
Cell And Developmental Biology
Keywords:
Nucleolar sequestration, nucleolus, physiological amyloids, ribosomal intergenic spacer, rIGSRNA, liquid-liquid phase separation, liquid-to-solid phase transition, complex coacervation, biomolecular condensates, beta-amyloid, MDM2, VHL, Cdc14, low complexity RNA, acidosis, heat shock
Online: 8 March 2019 (15:12:29 CET)