Yuan, X.; Zhang, J.; Shi, J.; Liu, W.; Kritchenkov, A.S.; Van Vlierberghe, S.; Wang, L.; Liu, W.; Gao, J. Cotton Fabric-Reinforced Hydrogels with Excellent Mechanical and Broad-Spectrum Photothermal Antibacterial Properties. Preprints2024, 2024040743. https://doi.org/10.20944/preprints202404.0743.v1
APA Style
Yuan, X., Zhang, J., Shi, J., Liu, W., Kritchenkov, A.S., Van Vlierberghe, S., Wang, L., Liu, W., & Gao, J. (2024). Cotton Fabric-Reinforced Hydrogels with Excellent Mechanical and Broad-Spectrum Photothermal Antibacterial Properties. Preprints. https://doi.org/10.20944/preprints202404.0743.v1
Chicago/Turabian Style
Yuan, X., Wanjun Liu and Jing Gao. 2024 "Cotton Fabric-Reinforced Hydrogels with Excellent Mechanical and Broad-Spectrum Photothermal Antibacterial Properties" Preprints. https://doi.org/10.20944/preprints202404.0743.v1
Abstract
Hydrogel wound dressings hold great potential in eliminating bacteria and accelerating the healing process. However, it remains a challenge to fabricate hydrogel wound dressings that simultaneously exhibit excellent mechanical and photothermal antibacterial properties. Here we report the development of polydopamine-functionalized graphene oxide/calcium alginate/Polypyrrole cotton fabric-reinforced hydrogels (abbreviated as rGO@PDA/CA/PPy FHs) for tackling bacterial infections. The mechanical properties of hydrogels were greatly enhanced by cotton fabric reinforcement and an interpenetrating structure, while excellent broad-spectrum photothermal antibacterial properties based on the photothermal effect were obtained by incorporating PPy and rGO@PDA. Results indicated that rGO@PDA/CA/PPy FHs exhibited superior tensile strength in both the warp (289±62.1N) and weft directions (142±23.0N) similar to cotton fabric. By incorporating PPy and rGO@PDA, the swelling ratio was significantly decreased from 673.5% to 236.6%, while photothermal conversion performance was significantly enhanced with a temperature elevated to 45.0 ℃. Due to the synergistic photothermal properties of rGO@PDA and PPy, rGO@PDA/CA/PPy FHs exhibited excellent bacteria-eliminating efficiency for S. aureus (0.57%) and E. coli (3.58%) after exposure to NIR for 20 min. We believe that the design of fabric-reinforced hydrogels could serve as a guideline for developing hydrogel wound dressings with improved mechanical properties and broad-spectrum photothermal antibacterial properties for infected wound treatment.
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This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
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