Atrian-Afiani, F.; Berger, B.; Draxl, C.; Sölkner, J.; Mészáros, G. Selective Sweeps in the Austrian Turopolje and Other Commercial Pig Populations. Animals 2023, 13, 3749. https://doi.org/10.3390/ani13243749
Atrian-Afiani, F.; Berger, B.; Draxl, C.; Sölkner, J.; Mészáros, G. Selective Sweeps in the Austrian Turopolje and Other Commercial Pig Populations. Animals 2023, 13, 3749. https://doi.org/10.3390/ani13243749
Atrian-Afiani, F.; Berger, B.; Draxl, C.; Sölkner, J.; Mészáros, G. Selective Sweeps in the Austrian Turopolje and Other Commercial Pig Populations. Animals 2023, 13, 3749. https://doi.org/10.3390/ani13243749
Atrian-Afiani, F.; Berger, B.; Draxl, C.; Sölkner, J.; Mészáros, G. Selective Sweeps in the Austrian Turopolje and Other Commercial Pig Populations. Animals 2023, 13, 3749. https://doi.org/10.3390/ani13243749
Abstract
The goal of our study was to identify signatures of selection in the Turopolje pigs and other commercial pig breeds. We conducted a comprehensive analysis of five datasets, including one local pig breed (Turopolje) and four commercial pig breeds (Large White, Landrace, Pietrain, and Duroc), using strict quality control measures. Our final dataset consisted of 485 individuals and 54,075 single nucleotide polymorphisms (SNPs).To detect selection signatureswithin these pig breeds, we utilized the XP-EHH and XP-nSL methodologies, which allowed us to identify candidate genes that have been subject to positive selection. Our analysis consistently highlighted the PTBP2 and DPYD genes as commonly targeted by selection across all studied breeds. Both of these genes are associated with muscular development in pigs and other species. Furthermore, in the Large White breed a number of genes were detected by the two methods, such as ATP1A1, CASQ2, CD2, IGSF3, MAB21L3, NHLH2, SLC22A15, VANGL1. In Duroc breed a different set of genes was detected, such as ARSB, BHMT, BHMT2, DMGDH, JMY. The function of these genes was related to body weight, production efficiency and meat quality, average daily gain and other similar traits. Overall, our results have identified a number of genomic regionsthat are under selective pressure between local and commercial pig breeds. This information can help to improve our understanding of the mechanisms underlying pig breeding, and ultimately contribute to the development of more efficient and sustainable pig production practices. Our study highlights the power of using multiple genomic methodologies to detect genetic signatures of selection, and provides important insights into the genetic diversity of pig breeds.
Keywords
Selection Signatures; Genomic Analysis; Muscular Development Genes
Subject
Biology and Life Sciences, Animal Science, Veterinary Science and Zoology
Copyright:
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
