Submitted:
17 February 2026
Posted:
18 February 2026
You are already at the latest version
Abstract
Childhood obesity is a globally pervasive condition driven not only by lifestyle and environmental factors but also by complex molecular mechanisms. These mechanisms involve genetic predisposition, epigenetic regulation, hormonal signaling pathways, adipose tissue biology, immuno-inflammatory responses, and interactions with environmental endocrine disruptors. This review synthesizes current evidence from scientific articles, systematic reviews, and mechanistic studies to elucidate how molecular processes shape the development, onset, and progression of obesity in children. Understanding these pathways is critical for developing precise prevention strategies and targeted interventions.
Keywords:
childhood obesity
; genetic
; epigenetic
; adipose tissue
; adipocitokynes
; molecular pathways
Copyright: This open access article is published under a Creative Commons CC BY 4.0 license, which permit the free download, distribution, and reuse, provided that the author and preprint are cited in any reuse.
