The importance of the infrastructure is associated with the value of the infrastructure, the greater the importance of infrastructure, the greater its value. The concept of the importance of road infrastructure can take on a different value instead of different points of view. For example, roads can be evaluated from an economic, social, political, and military, among others. In 2021, the Lazio Regional Road Authority (ASTRAL) requested assistance from the Research Center for Transport and Logistics (CTL) to develop a composite scoring index (Regional Index, Ri) that would rank the relative importance of ASTRAL–maintained roadway network. The Ri index is expressed numerically between values from 1 to 5 (with 5 representing the highest importance). It includes the following variables: Population density, AADT, road traffic crashes, accessibility to point of interest, maintenance cost, air emissions, and noise pollution. The methodology includes the following steps. First, the variables were selected on the basis of their reliability, measurability, coverage and relevance to the phenomenon to be measured. Then, the data collection and normalization of the variables on a scale of 1 to 5 were carried out. Subsequently, through a multicriteria analysis, the variables were weighted and added. Finally, a sensitivity analysis was performed to evaluate which variables had the most influence on the final output of the formula. The methodology proposed has been implemented on the Region Lazio roadway network in order to obtain the Ri of the road segments.