This paper presents the first experimental study of the physical properties of the millimeter-wave radio response of aqueous media and biological objects to external centimeter-wave electromagnetic radiation. It has been hypothesized that the spectrum of the radio response to external millimeter-wave radiation contains not only frequencies an order of magnitude or more lower than the radiation signal, but also frequencies close to the radiation signal and even frequencies higher than the external signal. This radio response property would suggest that each point in an aquatic environment exposed to electromagnetic waves could be a source of a radio response across an ultra-wide spectrum of electromagnetic frequencies. Experiments have demonstrated the presence of a radio response at frequencies of 61,2 GHz, 94 GHz, and 118 GHz when water is irradiated in the microwave range of 1,16–5,6 GHz at a power flux of 10 mW/cm2. The experimental results prompt a new examination of the comparative effects of 4G and 5G cellular electromagnetic waves on humans.