Submitted:
04 April 2025
Posted:
08 April 2025
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Abstract
Keywords:
1. Introduction
2. Materials and Methods
2.1. Study population
2.2. Data Collection
2.3. Statistical Analysis
3. Results
4. Discussion
5. Conclusions
Acknowledgments:
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Conflicts of Interest
References
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| Groups | Departments |
|---|---|
| Internal Medicine | Cardiology |
| Pulmonology | |
| Gastro enterology | |
| Nephrology | |
| Endocrinology | |
| Hemato-oncology | |
| Infectious diseases | |
| Allergy | |
| Rhematology | |
| Neurology | |
| Rehabilitation | |
| Psychiatry | |
| Geriatrics | |
| Emergency | |
| Surgery | General Surgery |
| Orthopedic Surgery | |
| Neuro-Surgery | |
| Thoracic Surgery | |
| Otorhinolaryngology | |
| Plastic Surgery | |
| Urology | |
| Dental Surgery | |
| Obstetrics and Gynaecology | |
| Ophthalmology |
| Variables | Frequency or mean (±SD) |
Internal medicine | Surgical | Chi-square or T (p-value) |
|---|---|---|---|---|
| Demographics | ||||
| Sex, male, n(%) | ||||
| Age, mean (± SD) | 67.59 (±14.752) | 67.53 (±14.352) | 67.72 (±15.610) | -0.130 (0.897) |
| Height, mean (± SD) | 161.807 (±9.349) | 162.04 (±9.261) | 161.31 (±9.545) | 0.806 (0.421) |
| Weight, mean (± SD) | 60.70 (±12.184) | 59.43 (±11.317) | 63.39 (±13.488) | -3.411 (0.001) |
| BMI, mean (± SD) | 23.14 (±4.01) | 22.61 (±3.816) | 24.27 (±4.199) | -4.353 (< 0.001) |
| Length of stay, mean (± SD) | 27.80 (±35.905) | 24.63 (±28.367) | 34.49 (±47.520) | -2.421 (0.016) |
| Time of falls | ||||
| Day shift (7 a.m. – 3 p.m.) | 154 (31.1) | 108 (32.1) | 46 (28.9) | 2.053 (0.358) |
| Evening shift (3 p.m. – 11 p.m.) | 147 (29.7) | 93 (27.7) | 54 (34.0) | |
| Night shift (11 p.m. – 7 a.m.) | 194 (39.2) | 135 (40.2) | 59 (37.1) | |
| Underlying disease, n (%) | ||||
| Cardiovascular disease | 275 (55.6) | 171 (50.9) | 104 (65.4) | 9.210 (0.002) |
| Neurological disease | 80 (16.2) | 63 (18.8) | 17 (10.7) | 5.172 (0.023) |
| Respiratory disease | 82 (16.6) | 67 (19.9) | 15 (9.4) | 8.620 (0.003) |
| Malignancy, n (%) | ||||
| In treatment | 87 (17.6) | 74 (22.0) | 13 (8.2) | 14.487 (0.001) |
| End of treatment | 34 (6.9) | 23 (6.8) | 11 (6.9) | |
| No treatment | 374 (75.6) | 239 (71.1) | 135 (84.9) | |
| Musculoskelectal disease, n (%) | 89 (18.0) | 48 (14.3) | 41 (25.8) | 9.680(0.002) |
| Digestive/urinary system disease, n (%) | 236 (47.7) | 165 (49.1) | 71 (44.7) | 0.858(0.354) |
| Eye disease (Cataract), n (%) | 33 (6.7) | 16 (4.8) | 17 (10.7) | 6.099 (0.014) |
| Alcohol, n (%) | ||||
| Present | 102 (20.6) | 65 (19.3) | 37 (23.3) | 9.823 (0.007) |
| Past | 77 (15.6) | 64 (19.0) | 13 (8.2) | |
| Not applicable | 316 (63.8) | 207 (61.6) | 109 (68.6) | |
| Smoking, n (%) | ||||
| Present | 121 (24.4) | 79 (23.5) | 42 (26.4) | 9.136 (0.010) |
| Past | 87 (17.6) | 71 (21.1) | 16 (10.1) | |
| Not applicable | 287 (58.0) | 186 (55.4) | 101 (63.5) | |
| Number of medications taken, mean (± SD) | 7.56 (±4.252) | 6.83 (±4.013) | 9.20 (±4.328) | -5.606 (< 0.001) |
| Fall risk medications, n (%) | ||||
| Sleep sedative/psychotropic drug | 43 (8.7) | 28 (8.3) | 15 (9.4) | 0.165 (0.685) |
| Antidepressants | 42 (8.5) | 28 (8.3) | 14 (8.8) | 0.031 (0.860) |
| Anxiolytics | 83 (16.8) | 61 (18.2) | 22 (13.8) | 1.442 (0.230) |
| Antipsychotics | 118 (23.8) | 85 (25.3) | 33 (20.8) | 1.227 (0.268) |
| Narcotic analgesics | 95 (19.2) | 64 (19.0) | 31 (19.5) | 0.014 (0.906) |
| Anticonsulsant | 79 (16.0) | 42 (12.5) | 37 (23.3) | 9.334 (0.002) |
| Diuretic | 75 (15.2) | 60 (17.9) | 15 (9.4) | 5.956 (0.015) |
| Laxative | 123 (24.8) | 81 (24.1) | 42 (26.4) | 0.308 (0.579) |
|
Duration of fall-risk medication use up to the time of the fall occurrence, n(%) | ||||
| Sleep sedative/psychotropic drug | 7.33 (±12.727) | 5.39 (±5.659) | 10.93 (±20.069) | -1.375 (0.088) |
| Antidepressants | 6.88 (±6.444) | 6.46 (±5.997) | 7.71 (±7.426) | -0.588 (0.560) |
| Anxiolytics | 7.14 (±6.964) | 6.08 (±5.838) | 10.09 (±8.922) | -1.961 (0.060) |
| Antipsychotics | 8.51 (±8.731) | 8.27 (±7.921) | 9.12 (±10.653) | -0.473 (0.637) |
| Narcotic analgesics | 5.39 (±5.788) | 6.17 (±6.558) | 3.77 (±3.263) | 2.379 (0.019) |
| Anticonsulsant | 11.38 (±13.058) | 11.33 (±13.935) | 11.43 (±12.178) | -0.033 (0.973) |
| Diuretic | 8.89 (±12.081) | 7.62 (±9.655) | 14.00 (±18.540) | -1.290 (0.215) |
| Laxative | 8.93 (±9.928) | 9.28 (±10.228) | 8.26 (±9.407) | 0.540 (0.590) |
| Mental status (Not included semi-coma), n (%) | ||||
| Alert | 420 (84.8) | 284 (84.5) | 136 (85.5) | 0.086 (0.770) |
| Confuse | 61 (12.3) | 42 (12.5) | 19 (11.9) | 0.030 (0.862) |
| Drowsy | 8 (1.6) | 6 (1.8) | 2 (1.3) | 0.189 (0.664) |
| Stupor | 1 (0.2) | 0 (0.0) | 1 (0.6) | 2.117 (0.146) |
| Activity status, n (%) | ||||
| Independent | 181 (36.6) | 146 (43.5) | 35 (22.0) | 21.388 (< 0.001) |
| Required help | 266 (53.7) | 156 (46.4) | 110 (69.2) | 22.447 (< 0.001) |
| Bed ridden status | 43 (8.7) | 30 (8.9) | 13 (8.2) | 0.077 (0.781) |
| Morse fall scale, mean (± SD) | ||||
| The time of admission | 28.27 (±17.451) | 29.34 (±16.585) | 25.85 (±19.096) | 1.848 (0.066) |
| The time of fall occurrence | 54.49 (±18.147) | 53.85 (±18.229) | 55.85 (±17.954) | -1.144 (0.253) |
| Use of the restraint band, n (%) | ||||
| Yes | 14 (2.8) | 11 (3.3) | 3 (1.9) | |
| No | 481 (97.2) | 325 (96.7) | 156 (98.1) | 0.755 (0.385) |
| Variables | Frequency or mean (±SD) |
Day shift (7 a.m. – 3 p.m.) |
Evening shift (3 p.m. ~ 11 p.m.) |
Night shift (11 p.m. – 7 a.m.) |
Chi-square or T (p-value) |
|---|---|---|---|---|---|
| Demographics | |||||
| Sex, male, n (%) | |||||
| Age, mean (± SD) | 67.59 (±14.752) | 65.58 (±15.029) | 65.79 (±14.908) | 70.56 (±13.976) | 6.597 (0.001) |
| Height, mean (± SD) | 161.807 (±9.349) | 162.00 (±9.260) | 161.52 (±9.079) | 161.87 (±9.658) | 0.107 (0.899) |
| Weight, mean (± SD) | 60.70 (±12.184) | 60.83 (±12.072) | 61.22 (±13.072) | 60.21 (±11.607) | 0.297 (0.743) |
| BMI, mean (± SD) | 23.14 (±4.010) | 23.16 (±4.072) | 23.35 (±4.049) | 22.97 (±3.952) | 0.371 (0.690) |
| Length of stay, mean (± SD) | 27.80 (±35.905) | 33.27 (±49.306) | 27.92 (±28.496) | 23.36 (±26.731) | 3.299 (0.038) |
| Department | |||||
| Internal medicine | 336 (67.9) | 135 (69.6) | 93 (63.3) | 108 (70.1) | 2.053 (0.358) |
| Surgery | 159 (32.1) | 59 (30.4) | 54 (36.7) | 46 (29.9) | |
| Underlying disease | |||||
| Cardiovascular disease | 275 (55.6) | 88 (57.1) | 81 (55.1) | 106 (54.6) | 0.235 (0.889) |
| Neurological disease | 80 (16.2) | 19 (12.3) | 24 (16.3) | 37 (19.1) | 2.878 (0.237) |
| Respiratory disease | 82 (16.6) | 24 (15.6) | 18 (12.2) | 40 (20.6) | 4.398 (0.111) |
| Malignancy | |||||
| In treatment | 87 (17.6) | 37 (19.1) | 24 (16.3) | 26 (16.9) | 4.072 (0.396) |
| End of treatment | 34 (6.9) | 17 (8.8) | 11 (7.5) | 6 (3.9) | |
| No treatment | 374 (75.6) | 140 (72.2) | 112 (76.2) | 122 (79.2) | |
| Musculoskelectal disease | 89 (18.0) | 26 (16.9) | 26 (17.7) | 37 (19.1) | 0.291 (0.865) |
| Digestive/urinary system disease | 236 (47.7) | 76 (49.4) | 65 (44.2) | 95 (49.0) | 1.008 (0.604) |
| Eye disease (Cataract) | 33 (6.7) | 20 (10.3) | 4 (2.7) | 9 (5.8) | 7.982 (0.018) |
| Alcohol | |||||
| Present | 102 (20.6) | 34 (17.5) | 37 (25.2) | 31 (20.1) | 6.711 (0.152) |
| Past | 77 (15.6) | 37 (19.1) | 15 (10.2) | 25 (16.2) | |
| Not applicable | 316 (63.8) | 123 (63.4) | 95 (64.6) | 98 (63.3) | |
| Smoking | |||||
| Present | 121 (24.4) | 36 (18.6) | 44 (29.9) | 41 (26.6) | 7.652 (0.105) |
| Past | 87 (17.6) | 40 (20.6) | 20 (13.6) | 27 (17.5) | |
| Not applicable | 287 (58.0) | 118 (60.8) | 83 (56.5) | 86 (55.8) | |
| Number of medications taken | 7.56 (±4.252) | 7.60 (±4.075) | 7.43 (±4.449) | 7.62 (±4.261) | 0.085 (0.918) |
| Fall risk medications | |||||
| Sleep sedative/psychotropic drug | 43 (8.7) | 12 (7.8) | 12 (8.2) | 19 (9.8) | 0.506 (0.777) |
| Antidepressants | 42 (8.5) | 14 (7.2) | 12 (8.2) | 16 (10.4) | 1.141 (0.565) |
| Anxiolytics | 83 (16.8) | 31 (16.0) | 25 (17.0) | 27 (17.5) | 0.157 (0.925) |
| Antipsychotics | 118 (23.8) | 52 (26.8) | 36 (24.5) | 30 (19.5) | 2.585 (0.275) |
| Narcotic analgesics | 95 (19.2) | 46 (23.7) | 25 (17.0) | 24 (15.6) | 4.300 (0.116) |
| Anticonsulsant | 79 (16.0) | 33 (17.0) | 29 (19.7) | 17 (11.0) | 4.496 (0.106) |
| Diuretic | 75 (15.2) | 24 (12.4) | 22 (15.0) | 29 (18.8) | 2.792 (0.248) |
| Laxative | 123 (24.8) | 46 (23.7) | 50 (34.0) | 27 (17.5) | 11.161 (0.004) |
|
Duration of fall-risk medication use up to the time of the fall occurrence | |||||
| Sleep sedative/psychotropic drug | 7.33 (±12.727) | 4.92 (±5.195) | 14.58 (±21.483) | 4.26 (±5.526) | 1.295 (0.295) |
| Antidepressants | 6.88 (±6.444) | 5.69 (±4.094) | 7.33 (±7.947) | 7.86 (±7.430) | 0.452 (0.640) |
| Anxiolytics | 7.14 (±6.964) | 6.96 (±5.619) | 6.48 (±7.200) | 7.84 (±7.925) | 0.272 (0.762) |
| Antipsychotics | 8.51 (±8.731) | 6.90 (±5.604) | 10.14 (±9.940) | 8.31 (±9.262) | 1.153 (0.319) |
| Narcotic analgesics | 5.39 (±5.788) | 7.25 (±6.271) | 3.44 (±3.969) | 5.48 (±6.124) | 2.764 (0.068) |
| Anticonsulsant | 11.38 (±13.058) | 10.53 (±11.912) | 13.00 (±13.792) | 10.39 (±13.210) | 0.347 (0.708) |
| Diuretic | 8.89 (±12.081) | 5.97 (±4.508) | 8.14 (±8.351) | 13.13 (±18.739) | 2.460 (0.093) |
| Laxative | 8.93 (±9.928) | 8.48 (±8.881) | 8.78 (±10.574) | 9.37 (±9.979) | 0.077 (0.926) |
| Mental status (Not included semi-coma) | |||||
| Alert | 420 (84.8) | 159 (82.0) | 128 (87.1) | 133 (86.4) | 2.102 (.350) |
| Confuse | 61 (12.3) | 30 (15.5) | 14 (9.5) | 17 (11.0) | 3.072 (0.215) |
| Drowsy | 8 (1.6) | 2 (1.0) | 4 (2.7) | 2 (1.3) | 1.644 (0.440) |
| Stupor | 1 (0.2) | 1 (0.5) | 0 (0.0) | 0 (0.0) | 1.555 (0.460) |
| Activity status | |||||
| Independent | 181 (36.6) | 66 (34.0) | 54 (36.7) | 61 (39.6) | 1.159 (0.560) |
| Required help | 266 (53.7) | 106 (54.6) | 79 (53.7) | 81 (52.6) | 0.144 (0.931) |
| Bed ridden status | 43 (8.7) | 20 (10.3) | 13 (8.8) | 10 (6.5) | 1.582 (0.453) |
| Morse fall scale | |||||
| The time of admission | 28.27 (±17.451) | 28.33 (±17.542) | 27.28 (±17.981) | 28.93 (±17.046) | 0.327 (0.721) |
| The time of fall occurrence | 54.49 (±18.147) | 51.27 (±17.524) | 53.32 (±16.808) | 57.91 (±19.089) | 6.286 (0.002) |
| Use of the restraint band | |||||
| Yes | 14 (2.8) | 5 (2.6) | 5 (3.4) | 4 (2.6) | |
| No | 481 (97.2) | 189 (97.4) | 142 (96.6) | 150 (97.4) | 0.250 (0.883) |
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