Preprint Article Version 1 Preserved in Portico This version is not peer-reviewed

Current Practice in the Treatment of Colorectal Liver Metastases by Irreversible Electroporation: A Focus-Group International Questionnaire Survey (LIVERMET-IRE-Q).

Harry V M Spiers
,
Saurabh Jamdar
,
Santhalingam Jegatheeswaran
,
Nicola De Liguori Carino
,
Panagiotis Stathakis
,
Vinotha Nadarajah
,
Krishna V Menon
,
Sanjay Pandanaboyana
ORCID logo ,
Adam E Frampton
,
Tze Min Wah
ORCID logo ,
Shahid Farid
,
Hassan Z Malik
,
Robert Jones
,
Jonathan Evans
,
Ajith K Siriwardena
* ORCID logo
Version 1 : Received: 2 April 2024 / Approved: 3 April 2024 / Online: 3 April 2024 (11:21:28 CEST)

How to cite: Spiers, H.V.M.; Jamdar, S.; Jegatheeswaran, S.; De Liguori Carino, N.; Stathakis, P.; Nadarajah, V.; Menon, K.V.; Pandanaboyana, S.; Frampton, A.E.; Wah, T.M.; Farid, S.; Malik, H.Z.; Jones, R.; Evans, J.; Siriwardena, A.K. Current Practice in the Treatment of Colorectal Liver Metastases by Irreversible Electroporation: A Focus-Group International Questionnaire Survey (LIVERMET-IRE-Q).. Preprints 2024, 2024040292. https://doi.org/10.20944/preprints202404.0292.v1 Spiers, H.V.M.; Jamdar, S.; Jegatheeswaran, S.; De Liguori Carino, N.; Stathakis, P.; Nadarajah, V.; Menon, K.V.; Pandanaboyana, S.; Frampton, A.E.; Wah, T.M.; Farid, S.; Malik, H.Z.; Jones, R.; Evans, J.; Siriwardena, A.K. Current Practice in the Treatment of Colorectal Liver Metastases by Irreversible Electroporation: A Focus-Group International Questionnaire Survey (LIVERMET-IRE-Q).. Preprints 2024, 2024040292. https://doi.org/10.20944/preprints202404.0292.v1

Abstract

Abstract: Background: Irreversible electroporation (IRE) is a form of non-thermal ablation that delivers pulses of high voltage electrical current between electrodes. The role of IRE in the treatment of colorectal hepatic metastases is unestablished. This study is an international ques-tionnaire survey of the use of IRE for colorectal hepatic metastases. Methods: A questionnaire addressing views on the use of IRE for colorectal liver metastases was circulated to clinicians with an interest and/or expertise in this technique. Results: 64 clinicians from 17 different countries replied to the questionnaire. Thirty-six (56%) had experience of treating patients with colorectal liver metastases with IRE. The preferred mode of delivery of IRE was percutaneous treatment under CT guidance. Thirty-three (70% respondents) used IRE exclusively for lesions in proximity to inflow or outflow structures. Twenty (43% respondents) used IRE as their sole ablative treat-ment whilst 19 (40% respondents) used IRE in combination with thermal ablation. The maximum number of lesions that could be treated by IRE was two and preferred size of lesion was

Keywords

colorectal cancer; liver metastases; ablation; irreversible electroporation; survey.

Subject

Medicine and Pharmacology, Surgery

Copyright: This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Download PDF

Comments (0)

We encourage comments and feedback from a broad range of readers. See criteria for comments and our Diversity statement.

Leave a public comment
Send a private comment to the author(s)
* All users must log in before leaving a comment
Views 0
Downloads 0
Comments 0
Metrics 0
Get PDF Cite Share 0
Bookmark BibSonomy Mendeley Reddit Delicious
×
Alerts
Notify me about updates to this article or when a peer-reviewed version is published.
We use cookies on our website to ensure you get the best experience.
Read more about our cookies here.