Version 1
: Received: 18 January 2024 / Approved: 18 January 2024 / Online: 18 January 2024 (11:08:45 CET)
How to cite:
Kim, K.; Lee, S.; Kwon, S.W.; Lee, Y.; Park, S.; Lee, C.H.; Kim, A.; Huh, G.Y.; Cho, K.; Choi, K.U. Alveolar Soft Part Sarcoma of Nasal Cavity showing Unusual Histologic Feature: A Case Report. Preprints2024, 2024011400. https://doi.org/10.20944/preprints202401.1400.v1
Kim, K.; Lee, S.; Kwon, S.W.; Lee, Y.; Park, S.; Lee, C.H.; Kim, A.; Huh, G.Y.; Cho, K.; Choi, K.U. Alveolar Soft Part Sarcoma of Nasal Cavity showing Unusual Histologic Feature: A Case Report. Preprints 2024, 2024011400. https://doi.org/10.20944/preprints202401.1400.v1
Kim, K.; Lee, S.; Kwon, S.W.; Lee, Y.; Park, S.; Lee, C.H.; Kim, A.; Huh, G.Y.; Cho, K.; Choi, K.U. Alveolar Soft Part Sarcoma of Nasal Cavity showing Unusual Histologic Feature: A Case Report. Preprints2024, 2024011400. https://doi.org/10.20944/preprints202401.1400.v1
APA Style
Kim, K., Lee, S., Kwon, S.W., Lee, Y., Park, S., Lee, C.H., Kim, A., Huh, G.Y., Cho, K., & Choi, K.U. (2024). Alveolar Soft Part Sarcoma of Nasal Cavity showing Unusual Histologic Feature: A Case Report. Preprints. https://doi.org/10.20944/preprints202401.1400.v1
Chicago/Turabian Style
Kim, K., Kyu-Sup Cho and Kyung Un Choi. 2024 "Alveolar Soft Part Sarcoma of Nasal Cavity showing Unusual Histologic Feature: A Case Report" Preprints. https://doi.org/10.20944/preprints202401.1400.v1
Abstract
Alveolar soft part sarcoma (ASPS) is a rare mesenchymal neoplasm. It affects young adults more and occurs more frequently in the extremities. ASPS is exceedingly rare in the nasal cavity. We report a case of ASPS in the nasal cavity of a 17-year-old female. Its most striking features included organoid and pseudoalveolar arrangement of tumor cells, which were large and polygonal, with vesicular nuclei and abundant eosinophilic cytoplasm rich in granules. There were PAS-positive, diastase-resistant crystalline rods within the cytoplasm. Our case displayed inapparent pseudoalveolar growth pattern and frank pleomorphism. The diagnosis of ASPS, which presents uncommon morphologic findings in unusual sites, is challenging. Recognition of ASPS is greatly assisted by attention to its characteristic cytological features, including intracytoplasmic crystals and immunohistochemistry showing absence of skeletal muscle, epithelial, and neuroendocrine markers.
Keywords
alveolar soft part sarcoma; nasal cavity; pathology; TFE3
Subject
Medicine and Pharmacology, Pathology and Pathobiology
Copyright:
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
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