Simpson, M.; Hendrickson, D.A.; Hyatt, D.R.; Rao, S. Comparison of In Vitro Bacterial Susceptibility to Common and Novel Equine Wound Care Dressings. Animals2024, 14, 776.
Simpson, M.; Hendrickson, D.A.; Hyatt, D.R.; Rao, S. Comparison of In Vitro Bacterial Susceptibility to Common and Novel Equine Wound Care Dressings. Animals 2024, 14, 776.
Simpson, M.; Hendrickson, D.A.; Hyatt, D.R.; Rao, S. Comparison of In Vitro Bacterial Susceptibility to Common and Novel Equine Wound Care Dressings. Animals2024, 14, 776.
Simpson, M.; Hendrickson, D.A.; Hyatt, D.R.; Rao, S. Comparison of In Vitro Bacterial Susceptibility to Common and Novel Equine Wound Care Dressings. Animals 2024, 14, 776.
Abstract
The goal of this study was to determine the relative susceptibility of four common equine wound pathogens to ten different types of antimicrobial agents based on minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC). Additionally, to describe the comparison of bactericidal activity of medical grade Manuka honey, local honey, and commercial, food-grade honey to other commonly used wound dressings. The objective is to provide veterinary practitioners with comparative data on the use of a variety of antimicrobial dressings for inhibiting growth of common wound bacteria. MIC and MBC for Manuka, store, and local honeys were comparable to those of sterile gauze, sugar, and hypertonic saline. Across bacterial species, local honey proved to have more bactericidal activity when compared to Manuka and commercial, food-grade honey. The MIC and MBC for PHMB gauze and foam was consistently at a higher dilution compared to the other antimicrobials. The majority of antimicrobials exhibited stronger inhibitory and bactericidal activity against a Streptococcus zooepidemicus isolate obtained from a wound compared to other bacteria that were ATCC lab acclimated. Additional research for in-vivo applications needs to be done to see whether differences exist in effective wound management.
Biology and Life Sciences, Animal Science, Veterinary Science and Zoology
Copyright:
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