Preprint Review Version 2 Preserved in Portico This version is not peer-reviewed

The Past, Present and Future in the Diagnosis of a Neglected Sexually Transmitted Infection: Trichomoniasis

Version 1 : Received: 24 December 2023 / Approved: 25 December 2023 / Online: 27 December 2023 (05:37:47 CET)
Version 2 : Received: 27 January 2024 / Approved: 29 January 2024 / Online: 29 January 2024 (04:49:11 CET)

A peer-reviewed article of this Preprint also exists.

Ibáñez-Escribano, A.; Nogal-Ruiz, J.J. The Past, Present, and Future in the Diagnosis of a Neglected Sexually Transmitted Infection: Trichomoniasis. Pathogens 2024, 13, 126. Ibáñez-Escribano, A.; Nogal-Ruiz, J.J. The Past, Present, and Future in the Diagnosis of a Neglected Sexually Transmitted Infection: Trichomoniasis. Pathogens 2024, 13, 126.

Abstract

More than one million curable sexually transmitted infections occur every day. Trichomonas vaginalis is one of the main responsible for these epidemiological data, however, the diagnosis of this protozoan is still mainly based on microscopic and culture identification. The commerciali-zation of immunological tests and the development of molecular techniques have improved the sensitivity of classical methods. Nevertheless, the fact that trichomoniasis is a neglected parasitic infection, hinders the development of novel techniques and their implementation in routine di-agnosis. This review article shows the different methods developed to identify T. vaginalis in population and the difficulties to diagnose male and asymptomatic patients. The importance of including this parasite in routine gynecological screening, especially in pregnant women, and the importance of considering T. vaginalis as an indicator of high-risk sexual behavior is also discussed.

Keywords

trichomoniasis; STI; wet mount; culture; diagnosis; NAAT; point-of-care

Subject

Biology and Life Sciences, Parasitology

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