Preprint Article Version 1 Preserved in Portico This version is not peer-reviewed

Organic and Inorganic Selenium Compounds Affected Lipidomic Profile of Spleen of Lambs Fed with Diets Enriched in Carnosic Acid and Fish Oil

Version 1 : Received: 11 November 2023 / Approved: 13 November 2023 / Online: 13 November 2023 (09:52:53 CET)

A peer-reviewed article of this Preprint also exists.

Białek, M.; Białek, A.; Wojtak, W.; Czauderna, M. Organic and Inorganic Selenium Compounds Affected Lipidomic Profile of Spleen of Lambs Fed with Diets Enriched in Carnosic Acid and Fish Oil. Animals 2024, 14, 133. Białek, M.; Białek, A.; Wojtak, W.; Czauderna, M. Organic and Inorganic Selenium Compounds Affected Lipidomic Profile of Spleen of Lambs Fed with Diets Enriched in Carnosic Acid and Fish Oil. Animals 2024, 14, 133.

Abstract

The purpose of these studies was to investigate effect of selenate (Se6), selenized yeast (SeYe) and carnosic acid (CA) supplementation to the diet containing fish oil (F-O) and rapeseed oil (R-O) on contents of fatty acids (FA), malondialdehyde (MDA), tocopherols (Ts) and total cholesterol (TCh) in lambs’ spleens. 24 male lambs (4 groups per 6 animals) have been fed: the control diet - the basal diet (BD) enriched in F-O and R-O; the CA diet - BD enriched in F-O, R-O and CA; the SeYeCA diet - BD enriched in F-O, R-O, CA and SeYe; the Se6CA diet - BD enriched in F-O, R-O, CA and Se6. Dietary modifications affected profiles of FA in spleens. The SeYeCA and Se6CA diets increased the docosapentaenoic acid preference in Δ4-desaturase, hence the higher content of docosahexaenoic acid was found in spleens of SeYe- or Se6-treated lambs than in spleens of animals receiving the CA and control diets. Experimental diets reduced the level of atherogenic FA in the spleen in comparison with the control diet. The experimental diets supplemented with SeYe or Se6 increased levels of TCh and Ts in spleens in comparison with the CA and control CA diets. The present studies documented that Se6, SeYe and CA influenced the metabolism of FA, Ts and cholesterol in spleens.

Keywords

selenium; carnosic acid; ovine spleen; fatty acids; tocopherols

Subject

Biology and Life Sciences, Animal Science, Veterinary Science and Zoology

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