Version 1
: Received: 3 August 2023 / Approved: 4 August 2023 / Online: 4 August 2023 (11:06:33 CEST)
How to cite:
Sousa, A.I.D.J.; Galvão, C.C.; Pires, P.S.; Salvarani, F.M. Blackleg: A Review of the Agent and Management of the Disease in Brazil. Preprints2023, 2023080411. https://doi.org/10.20944/preprints202308.0411.v1
Sousa, A.I.D.J.; Galvão, C.C.; Pires, P.S.; Salvarani, F.M. Blackleg: A Review of the Agent and Management of the Disease in Brazil. Preprints 2023, 2023080411. https://doi.org/10.20944/preprints202308.0411.v1
Sousa, A.I.D.J.; Galvão, C.C.; Pires, P.S.; Salvarani, F.M. Blackleg: A Review of the Agent and Management of the Disease in Brazil. Preprints2023, 2023080411. https://doi.org/10.20944/preprints202308.0411.v1
APA Style
Sousa, A.I.D.J., Galvão, C.C., Pires, P.S., & Salvarani, F.M. (2023). Blackleg: A Review of the Agent and Management of the Disease in Brazil. Preprints. https://doi.org/10.20944/preprints202308.0411.v1
Chicago/Turabian Style
Sousa, A.I.D.J., Prhiscylla Sadanâ Pires and Felipe Masiero Salvarani. 2023 "Blackleg: A Review of the Agent and Management of the Disease in Brazil" Preprints. https://doi.org/10.20944/preprints202308.0411.v1
Abstract
The genus Clostridium is an important group of pathogenic and nonpathogenic Gram-positive anaerobic bacteria with sporulation capacity and wide distribution in different environments, including the gastrointestinal tract of healthy and diseased animals and humans. Among the pathogenic species of the genus, Clostridium chauvoei stands out as a histotoxic agent. It causes important myonecroses such as blackleg, a disease with high lethality and mortality, especially in young cattle, and is responsible for significant losses to livestock worldwide. The pathogenic-ity of the disease is complex and has not yet been fully elucidated. The hypotheses cover pro-cesses from the initial absorption to the transport and deposition of the agent in the affected tis-sues. The virulence factors of C. chauvoei were divided into somatic and flagellar antigens and soluble antigens/toxins, which are the main antigens involved in vaccines against blackleg in Brazil and worldwide. This review provides important information on the first and current ap-proaches to the agent C. chauvoei and its virulence factors, as well as provides a compilation of data on Brazilian studies related to blackleg.
Biology and Life Sciences, Animal Science, Veterinary Science and Zoology
Copyright:
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
