Development of a Low-Temperature Process for the Formulation of Nanoemulsion-Gel Encapsulating Essential Oil: Investigation on the Wound Healing Effect

Badr Bahloul; Enis Ben Bnina; Assia Hamdi; Luis Castillo; Dhaou Baccar; Nesrine Kalboussi; Aymen Abbassi; Nathalie Mignet; Guido Flamini; José Vega-Baudrit

doi:10.20944/preprints202308.0150.v1

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preprints.org > medicine and pharmacology > dermatology > doi: 10.20944/preprints202308.0150.v1

Preprint Article Version 1 Preserved in Portico This version is not peer-reviewed

Development of a Low-Temperature Process for the Formulation of Nanoemulsion-Gel Encapsulating Essential Oil: Investigation on the Wound Healing Effect

Version 1 : Received: 1 August 2023 / Approved: 1 August 2023 / Online: 2 August 2023 (08:29:35 CEST)

How to cite: Bahloul, B.; Bnina, E.B.; Hamdi, A.; Castillo, L.; Baccar, D.; Kalboussi, N.; Abbassi, A.; Mignet, N.; Flamini, G.; Vega-Baudrit, J. Development of a Low-Temperature Process for the Formulation of Nanoemulsion-Gel Encapsulating Essential Oil: Investigation on the Wound Healing Effect. Preprints 2023, 2023080150. https://doi.org/10.20944/preprints202308.0150.v1 Bahloul, B.; Bnina, E.B.; Hamdi, A.; Castillo, L.; Baccar, D.; Kalboussi, N.; Abbassi, A.; Mignet, N.; Flamini, G.; Vega-Baudrit, J. Development of a Low-Temperature Process for the Formulation of Nanoemulsion-Gel Encapsulating Essential Oil: Investigation on the Wound Healing Effect. Preprints 2023, 2023080150. https://doi.org/10.20944/preprints202308.0150.v1

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MDPI and ACS Style

Bahloul, B.; Bnina, E.B.; Hamdi, A.; Castillo, L.; Baccar, D.; Kalboussi, N.; Abbassi, A.; Mignet, N.; Flamini, G.; Vega-Baudrit, J. Development of a Low-Temperature Process for the Formulation of Nanoemulsion-Gel Encapsulating Essential Oil: Investigation on the Wound Healing Effect. Preprints 2023, 2023080150. https://doi.org/10.20944/preprints202308.0150.v1

APA Style

Bahloul, B., Bnina, E.B., Hamdi, A., Castillo, L., Baccar, D., Kalboussi, N., Abbassi, A., Mignet, N., Flamini, G., & Vega-Baudrit, J. (2023). Development of a Low-Temperature Process for the Formulation of Nanoemulsion-Gel Encapsulating Essential Oil: Investigation on the Wound Healing Effect. Preprints. https://doi.org/10.20944/preprints202308.0150.v1

Chicago/Turabian Style

Bahloul, B., Guido Flamini and José Vega-Baudrit. 2023 "Development of a Low-Temperature Process for the Formulation of Nanoemulsion-Gel Encapsulating Essential Oil: Investigation on the Wound Healing Effect" Preprints. https://doi.org/10.20944/preprints202308.0150.v1

Abstract

This study develops an efficient, low-temperature process for formulating a nanoemulsion-based gel encapsulating Pituranthos tortuosus's essential oil, investigating its wound healing potential. The novel process ensured stable encapsulation of the medicinal plant's oil. The nanoemulsion was characterized using dynamic light scattering and transmission electron microscopy, followed by in vitro and in vivo tests to examine wound healing efficacy. Results revealed the gel's excellent stability, high encapsulation efficiency, and significant wound-healing effects. This research provides a new method for formulating Pituranthos tortuosus's essential oil nanoemulsion-based gel, emphasizing the potential role of plant-based therapies in healthcare advancement, and invites further exploration into the therapeutic applications of essential oil-encapsulating nanoemulsions.

Keywords

nanoemulsion; wound healing effect; essential oil

Subject

Medicine and Pharmacology, Dermatology

Copyright: This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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