Version 1
: Received: 19 July 2023 / Approved: 20 July 2023 / Online: 24 July 2023 (09:34:35 CEST)
How to cite:
Keele, T.; Hashemzadeh, M.; Movahed, M.R. Laparoscopic Cholecystectomy Has Better Safety in Comparison to Open Surgery for Occurrence of Death and Myocardial Infarction. Preprints2023, 2023071443. https://doi.org/10.20944/preprints202307.1443.v1
Keele, T.; Hashemzadeh, M.; Movahed, M.R. Laparoscopic Cholecystectomy Has Better Safety in Comparison to Open Surgery for Occurrence of Death and Myocardial Infarction. Preprints 2023, 2023071443. https://doi.org/10.20944/preprints202307.1443.v1
Keele, T.; Hashemzadeh, M.; Movahed, M.R. Laparoscopic Cholecystectomy Has Better Safety in Comparison to Open Surgery for Occurrence of Death and Myocardial Infarction. Preprints2023, 2023071443. https://doi.org/10.20944/preprints202307.1443.v1
APA Style
Keele, T., Hashemzadeh, M., & Movahed, M.R. (2023). Laparoscopic Cholecystectomy Has Better Safety in Comparison to Open Surgery for Occurrence of Death and Myocardial Infarction. Preprints. https://doi.org/10.20944/preprints202307.1443.v1
Chicago/Turabian Style
Keele, T., Mehrtash Hashemzadeh and Mohammad Reza Movahed. 2023 "Laparoscopic Cholecystectomy Has Better Safety in Comparison to Open Surgery for Occurrence of Death and Myocardial Infarction" Preprints. https://doi.org/10.20944/preprints202307.1443.v1
Abstract
Background: Laparoscopic cholecystectomy has gained popularity. The goal of this study was to evaluate outcome differences between open vs laparoscopic cholecystectomy. Method: Using a large NIS database and ICD-9 coding for open vs laparoscopic cholecystectomy, we compared inpatient outcomes for these two procedures regarding the occurrence of myocardial infarctions and mortality using uni- and multivariate analysis by studying 5 years of data from 2010 to 2015. Results: Open cholecystectomy was inferior to laparoscopic procedure with a higher occurrence of non-ST-elevation myocardial infarction (Non-STEMI), ST-elevation myocardial infarction (STEMI), and mortality in comparison to laparoscopic cholecystectomy. For example, using 2010 database, the occurrence of STEMI was 0.2 vs 0% (OR 3.1, CI 1.7-5.5, p<0.001), for Non-STEMI 1 vs 0.4% (OR 2.5 CI 2.0-3.0, p<0001) and for mortality 0.4 vs 0.4% (OR 9.2, CI 7.9-10.6, p<0001). After adjustment for age, obesity, diabetes, and hypertension, the occurrence of STEMI, Non-STEMI, and mortality remained higher in the open cholecystectomy cohort (mortality multivariate OR 6.4, CI 5.5-7.4, p<0001). Conclusion: Open cholecystectomy is associated with a higher rate of STEMI, Non-STEMI, and a markedly higher rate of mortality in comparison to the laparoscopic approach. Our study suggests that laparoscopic cholecystectomy should remain the first choice for patients needing gallbladder surgery.
Keywords
Laparoscopic surgery; open cholecystectomy; cardiac complication; laparoscopic intervention; laparoscopy
Subject
Biology and Life Sciences, Life Sciences
Copyright:
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
