Preprint Review Version 1 Preserved in Portico This version is not peer-reviewed

Resistance Exercise and Creatine Supplementation on Fat Mass in Adults ≪ 50 Years of Age: A Systematic Review and Meta-Analysis

Konstantinos Prokopidis
ORCID logo ,
Scott Forbes
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Darren G. Candow
* ,
Flavia Rusterholz
,
Bill Campbell
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Sergej Ostojic
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Version 1 : Received: 16 June 2023 / Approved: 19 June 2023 / Online: 19 June 2023 (09:06:57 CEST)

How to cite: Prokopidis, K.; Forbes, S.; Candow, D.G.; Rusterholz, F.; Campbell, B.; Ostojic, S. Resistance Exercise and Creatine Supplementation on Fat Mass in Adults ≪ 50 Years of Age: A Systematic Review and Meta-Analysis. Preprints 2023, 2023061334. https://doi.org/10.20944/preprints202306.1334.v1 Prokopidis, K.; Forbes, S.; Candow, D.G.; Rusterholz, F.; Campbell, B.; Ostojic, S. Resistance Exercise and Creatine Supplementation on Fat Mass in Adults ≪ 50 Years of Age: A Systematic Review and Meta-Analysis. Preprints 2023, 2023061334. https://doi.org/10.20944/preprints202306.1334.v1

Abstract

Adiposity is associated with adverse health conditions such as obesity, cardiovascular disease and type 2 diabetes. The combination of resistance exercise and creatine supplementation has been shown to decrease body fat % in adults ≥ 50 years of age. However, the effects in adults < 50 years of age is unknown. To address this limitation, we systematically reviewed the literature and performed several meta-analyses comparing studies that included resistance exercise and creatine supplementation to resistance exercise and placebo. Twelve studies were included involving 266 participants. Adults (< 50 years of age) that supplemented with creatine and performed resistance exercise experienced a significant reduction in body fat % (-1.19%, p=0.006) and a non-significant reduction in absolute fat mass (-0.09 kg, p=0.88). Collectively, the combination of resistance exercise and creatine supplementation produces a very small reduction in body fat % in adults < 50 years of age.

Keywords

body composition; ergogenic aids; adipose tissue; strength training

Subject

Biology and Life Sciences, Life Sciences

Copyright: This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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