Version 1
: Received: 25 May 2023 / Approved: 26 May 2023 / Online: 26 May 2023 (08:55:09 CEST)
Version 2
: Received: 6 June 2023 / Approved: 6 June 2023 / Online: 6 June 2023 (10:53:32 CEST)
How to cite:
Molinari, G. Proton Mechanisms of Neurotransmission and Calcium Signalling for Impulse Initiation, Development and Propagation. Preprints2023, 2023051895. https://doi.org/10.20944/preprints202305.1895.v1
Molinari, G. Proton Mechanisms of Neurotransmission and Calcium Signalling for Impulse Initiation, Development and Propagation. Preprints 2023, 2023051895. https://doi.org/10.20944/preprints202305.1895.v1
Molinari, G. Proton Mechanisms of Neurotransmission and Calcium Signalling for Impulse Initiation, Development and Propagation. Preprints2023, 2023051895. https://doi.org/10.20944/preprints202305.1895.v1
APA Style
Molinari, G. (2023). Proton Mechanisms of Neurotransmission and Calcium Signalling for Impulse Initiation, Development and Propagation. Preprints. https://doi.org/10.20944/preprints202305.1895.v1
Chicago/Turabian Style
Molinari, G. 2023 "Proton Mechanisms of Neurotransmission and Calcium Signalling for Impulse Initiation, Development and Propagation" Preprints. https://doi.org/10.20944/preprints202305.1895.v1
Abstract
Protons are gaining increasing attention as neurotransmitters due to their extraordinary abilities to rapidly transfer electrical charge, mobilize cellular calcium and modulate ion channels. How all this is possible is currently the subject of in-depth studies and discussions concerning not only neurophysiology, but also biological materials for artificial intelligence. In this short review, some biochemical mechanisms are described by which protons, in combination with calcium, can initiate firing in sensory neurons and transmit impulse across synapses. Furthermore, mechanisms are put forward concerning how three neurotransmitters, glutamate, gamma-aminobutyric acid and acetylcholine, are able to generate protons. The results of the numerous experimental works taken into consideration indicate that protons can play a fundamental role both in the generation and in the transmission of the nerve impulse.
Biology and Life Sciences, Neuroscience and Neurology
Copyright:
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
