Preprint Review Version 1 Preserved in Portico This version is not peer-reviewed

Atypical and unique transmission of monkeypox virus during the 2022 outbreak: an overview of the current state of knowledge

Version 1 : Received: 5 August 2022 / Approved: 8 August 2022 / Online: 8 August 2022 (03:57:03 CEST)

A peer-reviewed article of this Preprint also exists.

Riopelle, J.C.; Munster, V.J.; Port, J.R. Atypical and Unique Transmission of Monkeypox Virus during the 2022 Outbreak: An Overview of the Current State of Knowledge. Viruses 2022, 14, 2012. Riopelle, J.C.; Munster, V.J.; Port, J.R. Atypical and Unique Transmission of Monkeypox Virus during the 2022 Outbreak: An Overview of the Current State of Knowledge. Viruses 2022, 14, 2012.

Journal reference: Viruses 2022, 14, 2012
DOI: 10.3390/v14092012

Abstract

An ongoing monkeypox outbreak in non-endemic countries has resulted in the declaration of a Public Health Emergency of International Concern by the World Health Organization (WHO). Though monkeypox has long been endemic in regions of Sub-Saharan Africa, relatively little is known about its ecology, epidemiology, and transmission. Here, we consider the relevant research on both monkeypox and smallpox, a close relative, to make inferences about the current outbreak. Undetected circulation, combined with atypical transmission and case presentation, including mild and asymptomatic disease, have led to the spread of monkeypox in non-endemic regions. Broader availability of diagnostics, enhanced surveillance, and targeted education, combined with a better understanding of the routes of transmission, are critical to identify at-risk populations and design science-based countermeasures to control the current outbreak.

Keywords

monkeypox, transmission, outbreak, atypical presentation

Subject

LIFE SCIENCES, Virology

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