Submitted:
25 August 2020
Posted:
27 August 2020
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Preprints on COVID-19 and SARS-CoV-2
Abstract
Seroprevalence studies suggest that the number of PCR-confirmed COVID-19 cases is significantly smaller than the true number of infections. I study logintidual seroprevalence data from 7 sites across the US, from early April 2020 to June 27. I show that not only COVID-19 seroprevalence does not seem to increase over time, there is no clear association between the number of cases reported during a period and the change in seroprevalence during the same time. I conclude that as they are, seroprevalence studies can only be used in the qualitative sense and distinguish between populations with no COVID-19 exposure, to those populations where the virus had already started spreading.
Keywords:
Serology
; Seroprevalence
; Humoral response
; COVID-19
; serosurvey
; epidemiology
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