It seems that no scientific study has been able to find evidence of an afterlife, and the mechanism of consciousness is two of the most challenging questions. Here, I show a hypothesis for consciousness and the probability of an afterlife through three simple thought experiments and theoretical evidence, yet more studies need to precisely understand the mechanism. I found that consciousness might be discussed from three fundamental theories: (1) quantum-level particles of functional neurons in the brain according to quantum mechanics, (2) the brain and its more significant matter than quantum particles behave to general relativity, and (3) a new theory is needed if any other additional mechanism exists. Here, I hypothesize that when a person or animal dies, the selection of a new neuronal system's characteristic of a new life might depend on the characteristics of the finally evolving ultraquantum genome. Here, I suggest that the positive or adverse evolution of the ultraquantum genome depends on the natural evolution of the materialistic brain's cognition, including intelligence. When a brain dies, the ultraquantum particles might emit from the dead brain and simultaneously bond with the suitable early vacant nervous system anywhere in the universe/s, forming a new life with the impact of new nurture.