Version 1
: Received: 14 January 2022 / Approved: 17 January 2022 / Online: 17 January 2022 (12:37:22 CET)
Version 2
: Received: 20 July 2023 / Approved: 21 July 2023 / Online: 21 July 2023 (11:03:46 CEST)
Version 3
: Received: 31 July 2023 / Approved: 1 August 2023 / Online: 2 August 2023 (04:33:33 CEST)
Version 4
: Received: 18 October 2023 / Approved: 19 October 2023 / Online: 19 October 2023 (10:53:58 CEST)
How to cite:
Chesca, A.E.; Medetova, A.; Abdulina, G.; Kouchebekov, B.; Ahmetova, S.; Sandle, T. Laboratory Methods in Liver Pathology Diagnosis. Preprints2022, 2022010226. https://doi.org/10.20944/preprints202201.0226.v3
Chesca, A.E.; Medetova, A.; Abdulina, G.; Kouchebekov, B.; Ahmetova, S.; Sandle, T. Laboratory Methods in Liver Pathology Diagnosis. Preprints 2022, 2022010226. https://doi.org/10.20944/preprints202201.0226.v3
Chesca, A.E., Medetova, A., Abdulina, G., Kouchebekov, B., Ahmetova, S., & Sandle, T. (2023). Laboratory Methods in Liver Pathology Diagnosis. Preprints. https://doi.org/10.20944/preprints202201.0226.v3
Chicago/Turabian Style
Chesca, A.E., Saule Ahmetova and Tim Sandle. 2023 "Laboratory Methods in Liver Pathology Diagnosis" Preprints. https://doi.org/10.20944/preprints202201.0226.v3
Abstract
The study aimed to manage and to analyse the results of the laboratory tests, routinally practice for hepatitis C diagnosis, using blood tests.Comparison of ELISA method results (Enzyme-Linked Immunosorbent Assay) and chemiluminescence methods results. Statistical analysis of this study results, was performed using the laboratory informatic system. The results of the study are substantial and intricate reffering to comparision between two methods concretlly ELISA method (Enzyme-Linked Immunosorbent Assay) and chemiluminescence methods and their results. For this purpose, the results of preliminary EСL screening method of patients at risk for HCV who took part in the study, are presented in specific tables. More than good to mention that the correlations of results were used in order to identify a possible relationships between indicators of ELISA method and ECL index. In addition, correlations antibodies detected in electrochemiluminescence, ECL and Enzyme-Linked Immunosorbent Assay ELISA are pointed out. EСL and ELISA method results, are relevant for screening and for diagnostic confirmation in HCV risk patients. Unfortunately in the present study, were impossible to conclude about false-negative results. Good to know our opinion that RT-PCR technique, it is considered proper for the diagnosis of HCV.
Keywords
blood tests; hepatitis C virus; liver; laboratory techniques; diagnosis
Subject
Medicine and Pharmacology, Gastroenterology and Hepatology
Copyright:
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Commenter: ANTONELLA CHESCA
Commenter's Conflict of Interests: Author